Page last updated: 2024-08-24

hypusine and deoxyhypusine

hypusine has been researched along with deoxyhypusine in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19905 (26.32)18.7374
1990's7 (36.84)18.2507
2000's1 (5.26)29.6817
2010's6 (31.58)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Folk, JE; Hershey, JW; Park, MH; Smit-McBride, Z; Wolff, EC1
Abbruzzese, A; Beninati, S; Folk, JE1
Chen, KY; Dou, QP1
Chen, KY; Davis, RH; Seyfzadeh, M; Yang, YC1
Abbruzzese, A; Folk, JE; Park, MH1
Park, MH2
Gallop, PM; Paz, MA; Torrelio, BM1
Folk, JE; Liberato, DJ; Park, MH; Yergey, AL1
Beppu, T; Samejima, K; Shirahata, A1
Bergeron, RJ; McCosar, BH; Müller, R; Smith, RE; Weimar, WR; Yao, H; Zimmerman, CO2
Atemnkeng, V; Blavid, R; Frommholz, D; Kaiser, AE; Kusch, P; Marciniak, J; Marcus, K; Scheer, H; Tu, JM; Zhao, KH1
Deck, JA; Folk, JE; Fraser, CS; Lee, SB; Park, JH; Park, MH; Pegg, AE; Sokabe, M1
Dias, CA; Fraser, CS; Lee, SB; Park, JH; Park, MH; Sokabe, M; Valentini, SR1
Agostinelli, E; Kaiser, A; Khomutov, AR; Simonian, A1
Alhonen, L; Hyvönen, MT; Keinänen, TA; Khomutov, AR; Khomutov, M; Kochetkov, SN; Petit, M; Vepsäläinen, J; Weisell, J1
Böttger, LH; Han, Z; Hauber, J; Hilgenfeld, R; Klinke, S; Sakai, N; Trautwein, AX1
Carter, PJ; Deshayes, K; Dixit, VM; He, M; Song, A; Zhai, Q1

Other Studies

19 other study(ies) available for hypusine and deoxyhypusine

ArticleYear
Comparison of the activities of variant forms of eIF-4D. The requirement for hypusine or deoxyhypusine.
    The Journal of biological chemistry, 1991, May-05, Volume: 266, Issue:13

    Topics: Animals; Cadaverine; Cells, Cultured; Chromatography, Ion Exchange; Cricetinae; Eflornithine; Escherichia coli; Eukaryotic Translation Initiation Factor 5A; Humans; Lysine; Molecular Structure; Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; Periodic Acid; Puromycin; RNA-Binding Proteins; Spermidine; Substrate Specificity

1991
High-performance liquid chromatographic method for determination of hypusine and deoxyhypusine.
    Analytical biochemistry, 1990, Volume: 184, Issue:1

    Topics: Animals; Cattle; Cells, Cultured; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Lysine; Male; Microchemistry; Rats; Rats, Inbred Strains; Regression Analysis; Reproducibility of Results; Spectrometry, Fluorescence

1990
Characterization and reconstitution of a cell free system for NAD(+)-dependent deoxyhypusine formation on the 18 kDa eIF-4D precursor.
    Biochimica et biophysica acta, 1990, Nov-09, Volume: 1036, Issue:2

    Topics: Animals; Cell Line; Cell-Free System; Eukaryotic Translation Initiation Factor 5A; Lysine; Mice; Molecular Weight; NAD; Neuroblastoma; Peptide Initiation Factors; Protein Precursors; RNA-Binding Proteins

1990
Deoxyhypusine/hypusine formation on a 21,000-dalton cellular protein in a Neurospora crassa mutant in vivo and in vitro.
    Biochimica et biophysica acta, 1990, Feb-26, Volume: 1033, Issue:2

    Topics: Electrophoresis, Polyacrylamide Gel; Fungal Proteins; Isoelectric Focusing; Lysine; Mutation; Neurospora; Neurospora crassa; Polyamines

1990
Indirect assays for deoxyhypusine hydroxylase using dual-label ratio changes and oxidative release of radioactivity.
    Analytical biochemistry, 1986, May-01, Volume: 154, Issue:2

    Topics: Carbon Radioisotopes; Isotope Labeling; Lysine; Mixed Function Oxygenases; Oxidation-Reduction; Time Factors; Tritium

1986
Regulation of biosynthesis of hypusine in Chinese hamster ovary cells. Evidence for eIF-4D precursor polypeptides.
    The Journal of biological chemistry, 1987, Sep-15, Volume: 262, Issue:26

    Topics: Animals; Cell Line; Cricetinae; Cricetulus; Cycloheximide; Eflornithine; Female; Fibroblasts; Gene Expression Regulation; Lysine; Ovary; Protein Biosynthesis; Protein Processing, Post-Translational; Spermidine

1987
The identification of an eukaryotic initiation factor 4D precursor in spermidine-depleted Chinese hamster ovary cells.
    The Journal of biological chemistry, 1988, Jun-05, Volume: 263, Issue:16

    Topics: Animals; Cell Line; Cricetinae; Cricetulus; Eukaryotic Translation Initiation Factor 5A; Female; Isoelectric Point; Lysine; Ovary; Peptide Initiation Factors; Peptide Mapping; Protein Precursors; Protein Processing, Post-Translational; RNA-Binding Proteins; Spermidine

1988
Hydralazine inhibition of the post-translational hydroxylation of deoxyhypusine, a polyamine-derived amino acid.
    Biochemical pharmacology, 1984, Mar-01, Volume: 33, Issue:5

    Topics: Animals; Cell Line; Cricetinae; Cricetulus; DNA Replication; Female; Hydralazine; Hydroxylation; Lysine; Ovary; Protein Biosynthesis; Putrescine

1984
The biosynthesis of hypusine (N epsilon-(4-amino-2-hydroxybutyl)lysine). Alignment of the butylamine segment and source of the secondary amino nitrogen.
    The Journal of biological chemistry, 1984, Oct-10, Volume: 259, Issue:19

    Topics: Animals; Butylamines; Cell Line; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Female; Isotope Labeling; Lysine; Mass Spectrometry; Putrescine; Spermidine

1984
Determination of covalently bound hypusine and deoxyhypusine to protein using submilligram of protein samples by HPLC.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:1

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Chromatography, High Pressure Liquid; Lysine; Protein Binding; Rats; Reference Standards; Tumor Cells, Cultured

1996
Synthesis of reagents for the construction of hypusine and deoxyhypusine peptides and their application as peptidic antigens.
    Journal of medicinal chemistry, 1998, Sep-24, Volume: 41, Issue:20

    Topics: Animals; Antibodies, Monoclonal; CHO Cells; Cricetinae; Cross Reactions; Enzyme-Linked Immunosorbent Assay; Eukaryotic Translation Initiation Factor 5A; Haptens; Hemocyanins; Humans; Lysine; Maleimides; Mice; Mice, Inbred BALB C; Oligopeptides; Ovalbumin; Peptide Initiation Factors; RNA-Binding Proteins; Stereoisomerism

1998
Effect of polyamine analogues on hypusine content in JURKAT T-cells.
    Journal of medicinal chemistry, 1998, Sep-24, Volume: 41, Issue:20

    Topics: Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Biological Transport; Cell Division; Chromatography, High Pressure Liquid; Dansyl Compounds; Enzyme Inhibitors; Humans; Jurkat Cells; Leukemia L1210; Lysine; Ornithine Decarboxylase Inhibitors; Spermidine; Spermine; Tumor Cells, Cultured

1998
Completing the hypusine pathway in Plasmodium.
    The FEBS journal, 2009, Volume: 276, Issue:20

    Topics: Amino Acid Sequence; Animals; Blotting, Western; Gas Chromatography-Mass Spectrometry; Lysine; Mixed Function Oxygenases; Molecular Sequence Data; Molecular Structure; Plasmodium; Polymerase Chain Reaction; Protozoan Proteins; Sequence Homology, Amino Acid

2009
Inactivation of eukaryotic initiation factor 5A (eIF5A) by specific acetylation of its hypusine residue by spermidine/spermine acetyltransferase 1 (SSAT1).
    The Biochemical journal, 2011, Jan-01, Volume: 433, Issue:1

    Topics: Acetylation; Acetyltransferases; Animals; Cattle; Cell Line, Tumor; Eukaryotic Translation Initiation Factor 5A; Humans; Lysine; Peptide Initiation Factors; Protein Binding; RNA-Binding Proteins

2011
Production of active recombinant eIF5A: reconstitution in E.coli of eukaryotic hypusine modification of eIF5A by its coexpression with modifying enzymes.
    Protein engineering, design & selection : PEDS, 2011, Volume: 24, Issue:3

    Topics: Animals; Cattle; Cloning, Molecular; Escherichia coli; Eukaryotic Translation Initiation Factor 5A; Gene Expression; Genetic Vectors; Humans; Lysine; Mixed Function Oxygenases; Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; Recombinant Proteins; RNA-Binding Proteins; Temperature; Time Factors

2011
A rapid and robust assay for the determination of the amino acid hypusine as a possible biomarker for a high-throughput screening of antimalarials and for the diagnosis and therapy of different diseases.
    Amino acids, 2012, Volume: 42, Issue:5

    Topics: Animals; Antimalarials; Catalytic Domain; Chromatography, High Pressure Liquid; Eukaryotic Initiation Factor-5; Humans; Lysine; Malaria; Mice; Mixed Function Oxygenases; Oxidoreductases Acting on CH-NH Group Donors; Plasmodium; Protein Hydrolysates

2012
Enantiomers of 3-methylspermidine selectively modulate deoxyhypusine synthesis and reveal important determinants for spermidine transport.
    ACS chemical biology, 2015, Jun-19, Volume: 10, Issue:6

    Topics: Biological Transport; Cell Line, Tumor; Eflornithine; Eukaryotic Translation Initiation Factor 5A; Gene Expression; Humans; Lysine; Male; Ornithine Decarboxylase Inhibitors; Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; Protein Processing, Post-Translational; RNA-Binding Proteins; Spermidine; Stereoisomerism; Substrate Specificity

2015
Crystal Structure of the Peroxo-diiron(III) Intermediate of Deoxyhypusine Hydroxylase, an Oxygenase Involved in Hypusination.
    Structure (London, England : 1993), 2015, May-05, Volume: 23, Issue:5

    Topics: Catalytic Domain; Crystallography, X-Ray; Enzyme Stability; Eukaryotic Translation Initiation Factor 5A; Glycerol; Humans; Lysine; Mixed Function Oxygenases; Models, Molecular; Molecular Docking Simulation; Peptide Initiation Factors; RNA-Binding Proteins; Substrate Specificity

2015
Structural Analysis and Optimization of Context-Independent Anti-Hypusine Antibodies.
    Journal of molecular biology, 2016, Feb-13, Volume: 428, Issue:3

    Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antibody Affinity; Crystallography, X-Ray; Eukaryotic Translation Initiation Factor 5A; Humans; Lysine; Models, Molecular; Molecular Sequence Data; Peptide Initiation Factors; Protein Processing, Post-Translational; Rabbits; RNA-Binding Proteins

2016