Page last updated: 2024-09-03

hypocrellin a and phenol

hypocrellin a has been researched along with phenol in 162 studies

Compound Research Comparison

Studies
(hypocrellin a)
Trials
(hypocrellin a)
Recent Studies (post-2010)
(hypocrellin a)
Studies
(phenol)
Trials
(phenol)
Recent Studies (post-2010) (phenol)
1720726,5711012,591

Protein Interaction Comparison

ProteinTaxonomyhypocrellin a (IC50)phenol (IC50)
Carbonic anhydrase 1Homo sapiens (human)4.63
Carbonic anhydrase 2Homo sapiens (human)4.63
Carbonic anhydrase 6Homo sapiens (human)4.63
Carbonic anhydrase 3Bos taurus (cattle)4.63

Research

Studies (162)

TimeframeStudies, this research(%)All Research%
pre-199011 (6.79)18.7374
1990's40 (24.69)18.2507
2000's36 (22.22)29.6817
2010's55 (33.95)24.3611
2020's20 (12.35)2.80

Authors

AuthorsStudies
Jiang, LJ; Wang, ZJ; Xia, WL; Zhang, MH1
Nenghui, W; Zhiyi, Z1
Cao, EH; Cheng, LS; Xin, SM1
Fu, NW1
Misra, BR; Misra, HP; Zang, LY1
Chen, YJ; Pang, SZ; Qin, JF; Sun, JS; Yue, JC; Zhang, L1
Kishi, T; Tahara, S; Takahashi, S; Tanaka, C; Taniguchi, N; Tsuda, M1
Cheng, L; Du, J; Qin, J; Zhang, X1
Cheng, L; Du, J1
Misra, HP; Zang, LY; Zhang, ZY1
Lown, JW; Zhenjun, D1
Diwu, ZJ; Jiang, LJ; Zhang, MH1
Cheng, LS; Du, JA; Qin, JF; Zhang, XZ1
Jiang, LJ; Liang, L; Zhu, NJ1
Cheng, LS; Qin, JF; Sun, JS1
Tao, NB; Wang, DH; Xu, GR; Zang, LY; Zhang, ZY1
Chu, YX; Fu, NW1
An, JY; Ma, JS; Wang, CQ; Yan, F1
Bao, JN; Wang, JB1
Cheng, LS; Fu, SM; Wang, JZ1
An, JY; Jiang, LJ; Ma, JN; Zhang, MH1
Cao, EH; Cheng, LS1
Cheng, LS; Liu, XA1
Cheng, LS; Zheng, JH1
Cheng, LS; Wang, JZ1
Carpenter, SL; Fehr, MJ; Petrich, JW; Wannemuehler, Y1
Diwu, Z; Lown, JW; Meyer, T; Zimmermann, J1
Diwu, Z1
Begg, DA; Brown, K; Chlumecky, V; Diwu, ZJ; Huang, L; Liu, J; Lown, JW; Miller, GG; Moore, RB; Tulip, J1
Chen, J; Harris, L; Hudson, JB; Towers, GH; Yip, L; Zhou, J1
Li, JF; Wang, JZ; Zhang, XZ1
An, JY; Hu, YZ; Jiang, LJ1
Fotakis, C; Katsamouris, A; Liu, WQ; Papazoglou, TG1
Diwu, Z; Lown, JW1
Diwu, Z; Lown, JW; Zhang, C1
Brown, K; Diwu, Z; Estey, EP; Liu, J; Lown, JW; McPhee, MS; Miller, GG; Moore, RB; Tulip, J1
Misra, HP; Shi, X; Zang, LY1
Brown, K; Diwu, ZJ; Haugland, RP; Liu, J; Lown, JW; McPhee, MS; Miller, GG; Moore, RB; Tulip, J1
Koumantakis, E; Liu, WQ; Makrigiannakis, A; Papazoglou, TG; Relakis, C; Unsöld, E1
Guo, XQ; Li, F; Li, WY; Xu, JG; Zhu, QZ1
Abe, H; Hirayama, J; Horiuchi, M; Ikebuchi, K; Ikuta, K; Kamo, N; Kwon, KW; Ohnishi, Y; Sekiguchi, S; Shinagawa, M1
Xu, Y; Zhang, Z; Zhao, H1
Cao, EH; Li, JF; Ma, WJ; Zhang, J; Zhang, TC1
Chaloupka, R; Kocisova, E; Petrich, JW; Sureau, F1
Carpenter, S; English, DS; Park, J; Petrich, JW; Wannemuehler, Y1
Chaloupka, R; Obsil, T; Plásek, J; Sureau, F1
Das, K; Miskovsky, P; Petrich, JW; Smirnov, AV; Wen, J1
Chinsky, L; García-Ramos, JV; Jancura, D; Kocisová, E; Miskovský, P; Sánchez-Cortés, S1
An, JY; Gu, Y; He, YY; Huang, CG; Huang, JS; Huang, YC; Jiang, LJ; Wang, ZJ1
An, JY; He, YY; Jiang, LJ1
Chumanov, G; Datta, A; Petrich, JW; Smirnov, AV; Wen, J1
He, YY; Jiang, LJ1
Chen, S; Shen, J; Shen, T; Song, A; Wu, T; Zhang, M1
Hájiková, M; Lacková, A; Mirossay, A; Mirossay, L; Mojzis, J; Tóthová, J1
Chen, S; Shen, J; Shen, T; Song, A; Wu, T; Xu, S; Zhang, M1
Ali, SM; Chee, SK; Olivo, M; Yuen, GY5
Liu, W; Liu, WZ; Xie, JL; Zhang, HY1
Mirossay, A; Mirossay, L; Miskovský, P; Mojzis, J; Onderková, H; Tóthová, J1
Deininger, MH; Meyermann, R; Morgalla, MH; Schluesener, HJ; Weinschenk, T1
Ali, SM; Olivo, M1
Dong, YQ; Gu, YH; Jiang, LJ; Liu, J; Ma, L; Wu, S; Xia, AD; Zhao, JQ; Zhao, YW1
Chen, S; Shen, T; Xu, S; Zhang, M2
Ji, WZ; Li, C; Ma, L; Tai, H; Wang, ZH; Zhang, Y1
Gong, G; Huang, S; Li, M; Yu, F; Zeng, Z1
Chen, S; Shen, T; Wang, Z; Xu, S; Zhang, M; Zhang, X1
Bunschoten, A; Sakharov, DV; van Weelden, H; Wirtz, KW1
Chen, S; Lee, HY; Shen, T; Zhang, MH1
Dang, L; Qu, X; Seale, JP4
Jacob, MR; Khan, IA; Khan, SI; Li, Z; Ma, G; Pasco, DS; Tekwani, BL; Walker, LA1
Ji, HF; Shen, L; Zhang, HY1
Chin, W; Olivo, M1
Chen, J; Jiao, Q; Li, Z1
Liu, J; Wang, X; Xia, S; Zhang, B; Zhou, J1
Chen, J; Qiao, R; Wang, X; Xia, S; Zeng, Z; Zhang, B; Zhang, Y; Zhou, J1
Feng, YY; Gu, XT; Lu, TH; Wang, XS; Wei, SH; Wu, XH; Zhang, BW; Zhou, JH1
Chio-Srichan, S; Dumas, P; Jamme, F; Kascakova, S; Réfrégiers, M; Rouam, V1
Kozlowski, MC; Morgan, BJ; O'Brien, EM1
Cai, YJ; Liang, XH; Liao, XR; Meng, Q; Wang, L; Wu, K; Zhang, DB1
Feng, Y; Gu, X; Shen, J; Song, K; Wei, S; Wu, X; Zhou, J; Zhou, L1
Cai, Y; Ding, Y; Li, X; Liang, X; Liao, X; Sun, J1
Carroll, PJ; Kozlowski, MC; Li, J; O'Brien, EM1
Carroll, PJ; Kozlowski, MC; Morgan, BJ; Mulrooney, CA; O'Brien, EM1
Feng, YY; Liu, JH; Shen, J; Wei, SH; Yu, BY; Zhang, J; Zhou, JH; Zhou, L1
Feng, YY; Liu, JH; Ma, F; Shen, J; Wei, SH; Yu, BY; Zhou, JH; Zhou, L1
Bennaceur-Griscelli, A; Chio-Srichan, S; Dumas, P; Oudrhiri, N; Refregiers, M; Turhan, AG1
Feng, YY; Ning, YW; Shen, J; Wei, SH; Yu, BY; Zhou, JH; Zhou, L1
Du, W; Han, Y; Liang, J; Liang, Z; Sun, C1
Feng, Y; Shen, J; Wang, W; Wei, S; Yu, B; Zhou, J; Zhou, L1
Huang, CZ; Zhao, X1
Cai, Y; Rao, S; Su, Y; Sun, J; Yang, Y1
Cai, Y; Ding, Y; Liang, X; Liao, X; Sun, J; Zhang, D1
Jiang, HJ; Shen, J; Tang, J; Wang, W; Zhou, JH; Zhou, L1
Cai, Y; Hao, Z; Hu, M; Liao, X; Liu, J1
Lam, HA; Maidment, N; Nienhuis, R; Siegel, JM; Wu, MF1
Gao, Y; Jin, H; Li, H; Li, S; Li, Y; Ou, Z; Wang, X; Yang, G1
Chen, Z; Kong, M; Yin, Z; Zhang, J1
Han, L; Ma, F; Shen, J; Tang, J; Wang, F; Wei, S; Yang, C; Zhou, J; Zhou, L1
Du, W; Han, Y; Liang, Z; Sun, C; Yu, J1
Cui, Y; Fei, J; Gao, L; Li, H; Li, J; Zhao, J1
Huang, HY; Liu, ZM; Ma, F; Yang, C; Zhou, JH; Zhou, L1
Ge, X; Shen, J; Wei, S; Yu, B; Zhou, J; Zhou, L1
Chen, W; Du, W; Han, Y; Liang, J; Liang, Z; Sun, C; Wang, Y; Yu, J; Zou, X1
Ge, X; Han, L; Huang, H; Ma, F; Yang, C; Yang, X; Zhou, J; Zhou, L1
Ge, X; Han, L; Huang, H; Ma, F; Yang, C; Yang, X; Zhou, J1
Bottiroli, G; Bottone, MG; Croce, AC; Malatesta, M; Pellicciari, C; Santin, G; Scovassi, AI1
Ge, X; Li, F; Liu, J; Shen, J; Wei, S; Zhou, J; Zhou, L1
Gu, Z; Hu, Z; Jin, S; Liu, X; Ren, W; Tian, G; Yan, L; Yin, W; Zhang, X; Zhao, Y; Zhou, L1
Ge, X; Liu, J; Shen, J; Wei, S; Xie, W; Zhou, J; Zhou, L1
Ge, X; Jiang, H; Li, F; Shen, J; Wei, S; Zhou, J; Zhou, L1
Du, W; Han, Y; Liang, J; Liang, Z; Yu, J1
He, D; Liu, Q; Na, N; Ouyang, J; Yang, C; Zhao, Y1
Ge, X; Shen, J; Wei, S; Zhou, J; Zhou, L1
Fan, L; Gao, J; Hou, CL; Liu, XY; Shen, XY2
Cai, Y; Deng, H; Gao, R; Liao, X4
Chen, SL; Lin, X; Luo, ZM; Qi, SS; Yan, SZ; Zhao, N1
Cheng, Z; Deng, K; Deng, X; Hou, Z; Jin, D; Li, C; Lian, H; Lin, J1
Feng, Y; Hu, S; Liu, L; Liu, Y; Ren, Y; Xiu, J; Zhang, X1
Cai, Y; Chen, J; Deng, H; Gao, R; Liao, X1
Ma, YJ; Sun, CX; Wang, JW3
Lei, XY; Ma, YJ; Wang, JW; Zhang, MY1
Hua, HY; Ip, M; Leung, AW; Wang, XN; Xu, CS; Yung, PT1
Chao, Z; Dai, Z; Ju, H; Liu, Y; Ren, K; Yang, Y; Ye, D; Zhang, X; Zhang, Y1
Cai, Y; Deng, H; Gao, R; Guan, Z; Liao, X; Xu, Z; Zhao, Y; Zheng, X2
Cao, Y; Li, W; Wang, J; Wang, L; Wang, Y; Xu, G; Xu, J1
Chen, SL; Guo, BJ; Li, D; Lin, X; Yan, SZ; Zhao, N1
Ding, Y; Ge, J; Jia, Q; Lee, CS; Liu, W; Nan, F; Wang, P; Wu, J; Zhang, W; Zheng, X1
Ma, YJ; Wang, JW; Zheng, LP1
Chen, SL; Guo, LY; Li, Q; Tao, X; Wang, TS; Yan, SZ; Yang, Q; Yu, SQ1
Liu, W; Wang, P; Wu, J; Zhang, C; Zheng, X1
Guo, G; Niu, T; Shi, Y; Tian, Y; Tong, Y; Wang, G2
Deng, Y; Meng, L; Song, S; Sun, X; Wang, K; Wu, Q1
Ding, Y; Ge, J; Lee, CS; Liu, W; Ren, H; Wang, P; Wu, J; Zhang, W; Zheng, X1
Cai, Y; Deng, H; Fan, TP; Liang, W; Zheng, X1
Dong, H; Duan, W; Guo, L; Liu, W; Wang, X; Yao, X; Yu, S1
Chen, S; Dou, M; Guo, B; Yan, S; Yu, Y; Yue, Y; Zhao, N1
Li, XP; Ma, YJ; Wang, JW; Wang, Y1
Guo, YH; Li, XP; Wang, JW; Zhou, LL1
Cao, J; Liu, X; Qi, X; Shen, S; Wu, L; Zhao, K1
Lee, CS; Liu, W; Wang, P; Wu, J; Zhang, C; Zhang, W; Zheng, X1
Cai, G; Cheng, J; Huang, X; Lv, S; Wang, L; Xie, M; Yang, L; Yao, Y; Zhao, C; Zhao, H; Zhu, W1
Da, X; Gao, C; Jian, Y; Wang, X; Wang, Z; Yao, Y; Zhang, C; Zhou, Q1
Ji, HY; Li, XP; Shen, WH; Wang, JW; Wang, WJ1
Liao, B; Tian, X; Wen, Y; Wu, Z; Yan, X1
Li, XP; Ma, YJ; Shen, WH; Wang, JW; Wu, JY; Zhou, LL1
Cong, RP; Huang, QY; Li, XP; Shen, WH; Wang, JW; Zheng, LP; Zhou, LL2

Reviews

5 review(s) available for hypocrellin a and phenol

ArticleYear
[Advances in research on photosensitizers].
    Sheng li ke xue jin zhan [Progress in physiology], 1992, Volume: 23, Issue:1

    Topics: Animals; Antineoplastic Agents; Hematoporphyrin Derivative; Humans; Indoles; Isoindoles; Perylene; Phenol; Quinones; Radiation-Sensitizing Agents

1992
Hypocrellins and their use in photosensitization.
    Photochemistry and photobiology, 1990, Volume: 52, Issue:3

    Topics: Animals; Cell Survival; China; Medicine, Chinese Traditional; Perylene; Phenol; Photochemotherapy; Quinones; Radiation-Sensitizing Agents

1990
Novel therapeutic and diagnostic applications of hypocrellins and hypericins.
    Photochemistry and photobiology, 1995, Volume: 61, Issue:6

    Topics: Animals; Anthracenes; Antidepressive Agents; Antiviral Agents; Drugs, Chinese Herbal; Humans; Perylene; Phenol; Quinones; Radiation-Sensitizing Agents

1995
Release of regulators of angiogenesis following Hypocrellin-A and -B photodynamic therapy of human brain tumor cells.
    Biochemical and biophysical research communications, 2002, Nov-08, Volume: 298, Issue:4

    Topics: Angiogenesis Inducing Agents; Blotting, Western; Brain Neoplasms; Electrophoresis, Polyacrylamide Gel; Humans; Mass Spectrometry; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Quinones; Tumor Cells, Cultured

2002
Perylenequinones in photodynamic therapy: cellular versus vascular response.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2006, Volume: 25, Issue:1-2

    Topics: Animals; Anthracenes; Apoptosis; Blood Vessels; Humans; Neoplasms; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Quinones

2006

Other Studies

157 other study(ies) available for hypocrellin a and phenol

ArticleYear
Study on the nanosecond transient absorption spectra of hypocrellin A.
    Science in China. Series B, Chemistry, life sciences & earth sciences, 1992, Volume: 35, Issue:12

    Topics: Drugs, Chinese Herbal; Perylene; Phenol; Quinones; Radiation-Sensitizing Agents; Spectrometry, Fluorescence

1992
Relationship between photosensitizing activities and chemical structure of hypocrellin A and B.
    Journal of photochemistry and photobiology. B, Biology, 1992, Jul-15, Volume: 14, Issue:3

    Topics: Cyclic N-Oxides; Drugs, Chinese Herbal; Electron Spin Resonance Spectroscopy; Free Radicals; Light; Oxygen; Perylene; Phenol; Quinones; Radiation-Sensitizing Agents; Spin Labels; Structure-Activity Relationship

1992
DNA damage induced by hypocrellin-A photosensitization.
    International journal of radiation biology, 1992, Volume: 61, Issue:2

    Topics: Animals; Cell Division; DNA Damage; DNA, Single-Stranded; Drugs, Chinese Herbal; Perylene; Phenol; Photolysis; Quinones; Radiation-Sensitizing Agents

1992
Generation of free radicals during photosensitization of hypocrellin A and their effects on cardiac membranes.
    Photochemistry and photobiology, 1992, Volume: 56, Issue:4

    Topics: Animals; Antioxidants; Drugs, Chinese Herbal; Free Radicals; Intracellular Membranes; Light; Lipid Peroxidation; Microsomes; Myocardium; Perylene; Phenol; Quinones; Radiation-Sensitizing Agents; Swine

1992
[Hypocrellin B-sensitized photodamage on Na(+)-K+ ATPase and sodium permeability of human erythrocytes].
    Shi yan sheng wu xue bao, 1991, Volume: 24, Issue:3

    Topics: Erythrocytes; Humans; Lipid Peroxidation; Perylene; Phenol; Quinones; Radiation-Sensitizing Agents; Sodium; Sodium-Potassium-Exchanging ATPase

1991
New perylenequinones from Shiraia bambusicola.
    Planta medica, 1991, Volume: 57, Issue:4

    Topics: Ascomycota; Drugs, Chinese Herbal; Molecular Structure; Perylene; Phenol; Quinones

1991
[Hypocrellin A induced photodamage to the fluidity of human erythrocyte membranes and membranes of some phospholipid liposomes].
    Shi yan sheng wu xue bao, 1991, Volume: 24, Issue:4

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Drugs, Chinese Herbal; Erythrocyte Membrane; Humans; Liposomes; Membrane Fluidity; Perylene; Phenol; Phosphatidylethanolamines; Quinones; Radiation-Sensitizing Agents

1991
[The effect of hypocrellin A on the lipid bilayer of erythrocyte membrane].
    Shi yan sheng wu xue bao, 1991, Volume: 24, Issue:2

    Topics: Energy Transfer; Erythrocyte Membrane; Fluorescent Dyes; Humans; Lipid Bilayers; Membrane Fluidity; Perylene; Phenol; Quinones; Radiation-Sensitizing Agents

1991
EPR studies of trapped singlet oxygen (1O2) generated during photoirradiation of hypocrellin A.
    Photochemistry and photobiology, 1990, Volume: 52, Issue:4

    Topics: Electron Spin Resonance Spectroscopy; Oxygen; Perylene; Phenol; Photochemistry; Quinones; Singlet Oxygen

1990
Electronic spectra of hypocrellin A, B and their derivatives.
    Science in China. Series B, Chemistry, life sciences & earth sciences, 1990, Volume: 33, Issue:1

    Topics: Benz(a)Anthracenes; Perylene; Phenol; Quinones; Radiation-Sensitizing Agents; Spectrometry, Fluorescence

1990
[Hypocrellin A-sensitized photodamage on erythrocyte membrane protein and phospholipid].
    Shi yan sheng wu xue bao, 1990, Volume: 23, Issue:1

    Topics: Benz(a)Anthracenes; Erythrocyte Membrane; Humans; Light; Lipid Peroxidation; Membrane Proteins; Perylene; Phenol; Phospholipids; Quinones; Radiation-Sensitizing Agents; Spectrin

1990
The crystallographic structure of the photooxidized product of hypocrellin A and the study of the photodynamic action mechanism.
    Science in China. Series B, Chemistry, life sciences & earth sciences, 1990, Volume: 33, Issue:6

    Topics: Benz(a)Anthracenes; Crystallization; Molecular Structure; Perylene; Phenol; Quinones; Radiation-Sensitizing Agents

1990
[The study on hypocrellin A-sensitized photoinactivation of enzymes of human erythrocyte membranes].
    Shi yan sheng wu xue bao, 1989, Volume: 22, Issue:4

    Topics: Acetylcholinesterase; Adenosine Triphosphatases; Erythrocyte Membrane; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Perylene; Phenol; Quinones; Radiation-Sensitizing Agents

1989
Characteristics of the primary reaction of hypocrellin A photosensitization.
    Science in China. Series B, Chemistry, life sciences & earth sciences, 1989, Volume: 32, Issue:9

    Topics: Electron Spin Resonance Spectroscopy; Free Radicals; Light; Oxygen; Perylene; Phenol; Quinones; Radiation-Sensitizing Agents

1989
[Photodynamic action of hypocrellin A on hepatoma cell mitochondria and microsomes].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1989, Volume: 10, Issue:4

    Topics: Adenosine Triphosphatases; Animals; Female; Glucose-6-Phosphatase; Liver Neoplasms, Experimental; Mice; Microsomes, Liver; Mitochondria, Liver; Mitochondrial Swelling; Perylene; Phenol; Photochemotherapy; Quinones; Radiation-Sensitizing Agents

1989
Hypocrellin-A sensitized photooxidation of bilirubin.
    Photochemistry and photobiology, 1989, Volume: 50, Issue:6

    Topics: Bilirubin; Light; Oxidation-Reduction; Perylene; Phenol; Quinones; Radiation-Sensitizing Agents; Spectrophotometry

1989
[Clinical analysis and observation of hypocrellin photochemotherapy in the treatment of lichen amyloidosis: report of 37 cases].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1985, Volume: 7, Issue:5

    Topics: Adult; Aged; Amyloidosis; Female; Humans; Lichen Planus; Male; Middle Aged; Perylene; Phenol; Photochemotherapy; Quinones

1985
Effect of hypocrellin A sensitization on the lateral mobility of cell membrane proteins.
    Journal of photochemistry and photobiology. B, Biology, 1988, Volume: 2, Issue:3

    Topics: Animals; Fluorescence; L Cells; Membrane Proteins; Mice; Perylene; Phenol; Photochemotherapy; Quinones

1988
Photochemistry of hypocrellin A (IV)--Hypocrellin A-sensitized photooxidation of diphenylamine.
    Scientia Sinica. Series B, Chemical, biological, agricultural, medical & earth sciences, 1988, Volume: 31, Issue:4

    Topics: Acetonitriles; Aniline Compounds; Diphenylamine; Drug Interactions; Light; Methanol; Perylene; Phenol; Photochemistry; Quinones; Radiation-Sensitizing Agents

1988
[DNA single-strand breakage and its rejoining in HeLa cells caused by hypocrellin A photosensitization].
    Shi yan sheng wu xue bao, 1988, Volume: 21, Issue:1

    Topics: DNA Damage; DNA Repair; DNA, Single-Stranded; HeLa Cells; Hematoporphyrin Photoradiation; Humans; Perylene; Phenol; Photochemotherapy; Quinones; Radiation-Sensitizing Agents

1988
[Effect of lipid peroxidation on hypocrellin A-photosensitized cross-linking of membrane protein].
    Shi yan sheng wu xue bao, 1987, Volume: 20, Issue:3

    Topics: Butylated Hydroxytoluene; Erythrocyte Membrane; Humans; Malondialdehyde; Membrane Lipids; Membrane Proteins; Perylene; Phenol; Photochemistry; Quinones; Radiation-Sensitizing Agents; Vitamin E

1987
[Hypocrellin A-sensitized cross-linking of erythrocyte membrane proteins].
    Shi yan sheng wu xue bao, 1986, Volume: 19, Issue:4

    Topics: Amino Acids; Cross-Linking Reagents; Erythrocytes; Humans; Membrane Proteins; Perylene; Phenol; Photochemistry; Quinones; Radiation-Sensitizing Agents

1986
[Photodamage in human erythrocyte membranes, induced by new photosensitizer hypocrellin A].
    Shi yan sheng wu xue bao, 1985, Volume: 18, Issue:1

    Topics: Erythrocyte Membrane; Hematoporphyrin Photoradiation; Humans; Membrane Lipids; Membrane Proteins; Perylene; Phenol; Photochemotherapy; Quinones; Radiation-Sensitizing Agents

1985
Roles of oxygen and photoinduced acidification in the light-dependent antiviral activity of hypocrellin A.
    Biochemistry, 1995, Dec-05, Volume: 34, Issue:48

    Topics: Anthracenes; Antiviral Agents; HIV; Hydrogen-Ion Concentration; Light; Oxygen; Perylene; Phenol; Photochemistry; Quinones

1995
Design, synthesis and investigation of mechanisms of action of novel protein kinase C inhibitors: perylenequinonoid pigments.
    Biochemical pharmacology, 1994, Jan-20, Volume: 47, Issue:2

    Topics: Antibiotics, Antineoplastic; Calcium; Drug Design; Electron Spin Resonance Spectroscopy; Free Radicals; Light; Naphthalenes; Perylene; Phenol; Photochemistry; Pigments, Biological; Polycyclic Compounds; Protein Kinase C; Quinones; Structure-Activity Relationship

1994
Uptake kinetics and intracellular localization of hypocrellin photosensitizers for photodynamic therapy: a confocal microscopy study.
    Photochemistry and photobiology, 1995, Volume: 61, Issue:6

    Topics: Animals; Intracellular Fluid; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Microscopy, Fluorescence; Neoplasm Transplantation; Neoplasms, Experimental; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Quinones; Tumor Cells, Cultured

1995
Hypocrellin, from Hypocrella bambuase, is phototoxic to human immunodeficiency virus.
    Photochemistry and photobiology, 1994, Volume: 60, Issue:3

    Topics: 3T3 Cells; Animals; Anthracenes; Antiviral Agents; Cell Line; Cytomegalovirus; Darkness; HIV-1; Humans; Hypocreales; Light; Mice; Perylene; Phenol; Quinones; Radiation-Sensitizing Agents

1994
[An experimental study on photosensitization of cultured human cells with hypocrellin A].
    Shi yan sheng wu xue bao, 1994, Volume: 27, Issue:2

    Topics: Cell Division; Cells, Cultured; DNA, Neoplasm; Drugs, Chinese Herbal; Embryo, Mammalian; Fibroblasts; HeLa Cells; Humans; Perylene; Phenol; Photosensitizing Agents; Quinones

1994
Studies on the chelation of hypocrellin A with aluminium ion and the photodynamic action of the resulting complex.
    Journal of photochemistry and photobiology. B, Biology, 1994, Volume: 22, Issue:3

    Topics: Aluminum; Chelating Agents; Drugs, Chinese Herbal; Electron Spin Resonance Spectroscopy; Kinetics; Light; Molecular Structure; Perylene; Phenol; Photochemotherapy; Quinones; Radiation-Sensitizing Agents; Spectrophotometry, Infrared; Superoxides; Time Factors

1994
Laser-induced fluorescence detection of cardiovascular atherosclerotic deposits via their natural emission and hypocrellin (HA) probing.
    Journal of photochemistry and photobiology. B, Biology, 1994, Volume: 22, Issue:2

    Topics: Aorta, Abdominal; Arteriosclerosis; Autopsy; Coronary Artery Bypass; Femoral Artery; Humans; Lasers; Muscle, Smooth, Vascular; Perylene; Phenol; Quinones; Radiation-Sensitizing Agents; Spectrometry, Fluorescence

1994
Photosensitization with anticancer agents. 16. The photo-oxidation of hypocrellin A. A mechanism study using 18O labelling.
    Journal of photochemistry and photobiology. B, Biology, 1993, Volume: 18, Issue:2-3

    Topics: Antineoplastic Agents; Indicators and Reagents; Isotope Labeling; Kinetics; Light; Molecular Structure; Oxidation-Reduction; Oxygen Isotopes; Perylene; Phenol; Photosensitizing Agents; Quinones; Solvents; Spectrophotometry

1993
Photosensitization with anticancer agents. 18. Perylenequinonoid pigments as potential photodynamic therapeutic agents: preparation and photodynamic properties of amino-substituted hypocrellin derivatives.
    Anti-cancer drug design, 1993, Volume: 8, Issue:2

    Topics: Amination; Antineoplastic Agents; Perylene; Phenol; Photochemistry; Photosensitizing Agents; Quinones; Reactive Oxygen Species; Spectrum Analysis

1993
Hypocrellins as photosensitizers for photodynamic therapy: a screening evaluation and pharmacokinetic study.
    Cancer chemotherapy and pharmacology, 1996, Volume: 37, Issue:4

    Topics: Animals; Mice; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Quinones; Tumor Cells, Cultured

1996
EPR-spin trapping kinetic studies of superoxide radicals produced by photosensitized hypocrellin A. A photodynamic therapeutic agent.
    Biochemistry and molecular biology international, 1996, Volume: 38, Issue:4

    Topics: Electron Spin Resonance Spectroscopy; Half-Life; Kinetics; Perylene; Phenol; Photochemistry; Photochemotherapy; Photosensitizing Agents; Quinones; Spin Trapping; Superoxides

1996
Photosensitization by anticancer agents 21: new perylene- and aminonaphthoquinones.
    Free radical biology & medicine, 1996, Volume: 20, Issue:4

    Topics: Animals; Mice; Molecular Structure; Neoplasms, Experimental; Perylene; Phenol; Photochemotherapy; Quinones; Tumor Cells, Cultured

1996
Laser-induced fluorescence detection of malignancies in the female genital tract via their natural emission and hypocrellin (HA) probing.
    Journal of photochemistry and photobiology. B, Biology, 1997, Volume: 37, Issue:1-2

    Topics: Algorithms; Female; Genital Neoplasms, Female; Humans; Lasers; Perylene; Phenol; Photosensitizing Agents; Quinones; Spectrometry, Fluorescence

1997
Application of a novel fluorescence probe in the determination of nucleic acids.
    The Analyst, 1997, Volume: 122, Issue:9

    Topics: DNA; Fluorescent Dyes; Humans; Perylene; Phenol; Photosensitizing Agents; Quinones; RNA; Spectrometry, Fluorescence

1997
Photoinactivation of virus infectivity by hypocrellin A.
    Photochemistry and photobiology, 1997, Volume: 66, Issue:5

    Topics: Animals; Antiviral Agents; Cell Line; Dogs; HIV-1; Humans; Oxygen; Parvovirus, Canine; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Quinones; Singlet Oxygen; Vesicular stomatitis Indiana virus; Viral Proteins; Virulence

1997
Raman spectroscopic study of microcosmic and photosensitive damage on the liposomes of the mixed phospholipids sensitized by hypocrellin and its derivatives.
    Journal of photochemistry and photobiology. B, Biology, 1998, Volume: 43, Issue:1

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Argon; Hydrocarbons; Ions; Liposomes; Perylene; Phenol; Phosphates; Phosphatidylcholines; Phosphatidylethanolamines; Photosensitizing Agents; Quinones; Spectrum Analysis, Raman

1998
Photodynamic effects of hypocrellin A on three human malignant cell lines by inducing apoptotic cell death.
    Journal of photochemistry and photobiology. B, Biology, 1998, May-15, Volume: 43, Issue:2

    Topics: Apoptosis; DNA Fragmentation; HeLa Cells; Humans; Light; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Quinones; Tumor Cells, Cultured

1998
Hypocrellin A photosensitization involves an intracellular pH decrease in 3T3 cells.
    Photochemistry and photobiology, 1998, Volume: 68, Issue:1

    Topics: 3T3 Cells; Animals; Benzopyrans; Fluorescent Dyes; Hydrogen-Ion Concentration; Intracellular Fluid; Lasers; Mice; Naphthols; Perylene; Phenol; Photobiology; Photosensitizing Agents; Quinones; Rhodamines

1998
The role of oxygen in the antiviral activity of hypericin and hypocrellin.
    Photochemistry and photobiology, 1998, Volume: 68, Issue:4

    Topics: Adenosine Triphosphate; Animals; Anthracenes; Antiviral Agents; Horses; Infectious Anemia Virus, Equine; Light; Luminescent Measurements; Microbial Sensitivity Tests; Oxygen; Perylene; Phenol; Photochemistry; Quinones; Singlet Oxygen

1998
The effect of hypericin and hypocrellin-A on lipid membranes and membrane potential of 3T3 fibroblasts.
    Biochimica et biophysica acta, 1999, Apr-14, Volume: 1418, Issue:1

    Topics: 3T3 Cells; Animals; Anthracenes; Dimyristoylphosphatidylcholine; Lipid Bilayers; Membrane Fluidity; Membrane Potentials; Mice; Perylene; Phenol; Photochemistry; Photosensitizing Agents; Proteolipids; Quinones; Sodium-Potassium-Exchanging ATPase; Spectrometry, Fluorescence

1999
Photophysics of hypericin and hypocrellin A in complex with subcellular components: interactions with human serum albumin.
    Photochemistry and photobiology, 1999, Volume: 69, Issue:6

    Topics: Anthracenes; Energy Transfer; Fluorescence Polarization; Humans; In Vitro Techniques; Macromolecular Substances; Perylene; Phenol; Photochemistry; Quinones; Serum Albumin, Bovine

1999
Interaction of antiviral and antitumor photoactive drug hypocrellin A with human serum albumin.
    Journal of biomolecular structure & dynamics, 1999, Volume: 17, Issue:1

    Topics: Antineoplastic Agents; Antiviral Agents; Calorimetry; Drugs, Chinese Herbal; Humans; Molecular Structure; Perylene; Phenol; Photosensitizing Agents; Protein Binding; Quinones; Serum Albumin; Spectrum Analysis, Raman

1999
Pharmacokinetics, tissue distribution and photodynamic therapy efficacy of liposomal-delivered hypocrellin A, a potential photosensitizer for tumor therapy.
    Photochemistry and photobiology, 1999, Volume: 70, Issue:5

    Topics: Animals; Liposomes; Male; Mice; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Quinones; Sarcoma 180; Tissue Distribution

1999
Glycoconjugated hypocrellin: synthesis of [(beta-D-glucosyl)ethylthiyl]hypocrellins and photosensitized generation of singlet oxygen.
    Biochimica et biophysica acta, 1999, Oct-18, Volume: 1472, Issue:1-2

    Topics: Glycoconjugates; Oxygen; Perylene; Phenol; Photochemistry; Quinones; Singlet Oxygen; Spectrum Analysis

1999
Multidimensional reaction coordinate for the excited-state H-atom transfer in perylene quinones: importance of the 7-membered ring in hypocrellins A and B.
    Photochemistry and photobiology, 2000, Volume: 71, Issue:2

    Topics: Kinetics; Molecular Structure; Perylene; Phenol; Photochemistry; Photosensitizing Agents; Quinones; Solvents; Spectrophotometry

2000
Synthesis and EPR investigations of new aminated hypocrellin derivatives.
    Free radical biology & medicine, 2000, Jun-01, Volume: 28, Issue:11

    Topics: Amines; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Liposomes; Oxygen; Perylene; Phenol; Photochemistry; Photochemotherapy; Photosensitizing Agents; Quinones; Singlet Oxygen; Spectrophotometry; Superoxides

2000
Photodynamic action of amino substituted hypocrellins: EPR studies on the photogenerations of active oxygen and free radical species.
    Journal of photochemistry and photobiology. B, Biology, 2000, Volume: 57, Issue:1

    Topics: Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Lasers; Molecular Conformation; Molecular Structure; Perylene; Phenol; Photosensitizing Agents; Quinones; Spectrophotometry; Structure-Activity Relationship

2000
Hypocrellin and hypericin-induced phototoxicity of HL-60 cells: apoptosis or necrosis?
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2000, Volume: 7, Issue:6

    Topics: Anthracenes; Antineoplastic Agents; Apoptosis; Drugs, Chinese Herbal; HL-60 Cells; Humans; Necrosis; Perylene; Phenol; Photosensitizing Agents; Quinones

2000
New potential photodynamic therapeutic anti-cancer agents: synthesis and characterization of demethoxy amino-substituted hypocrellins.
    Anti-cancer drug design, 2000, Volume: 15, Issue:4

    Topics: Antineoplastic Agents; Cell Survival; Electron Spin Resonance Spectroscopy; HeLa Cells; Humans; Nuclear Magnetic Resonance, Biomolecular; Perylene; Phenol; Photochemistry; Photosensitizing Agents; Quinones; Reactive Oxygen Species; Superoxides

2000
Photodynamic-induced apoptosis of human nasopharyngeal carcinoma cells using Hypocrellins.
    International journal of oncology, 2001, Volume: 19, Issue:3

    Topics: Annexin A5; Apoptosis; Blotting, Western; Caspase 3; Caspase Inhibitors; Caspases; Cell Differentiation; DNA, Neoplasm; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; Humans; Nasopharyngeal Neoplasms; Perylene; Phenol; Phosphatidylserines; Photochemotherapy; Photosensitizing Agents; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Quinones; Tumor Cells, Cultured

2001
Photosensitization of hypomycin B--a novel perylenequinonoid pigment with only one intramolecular hydrogen bond.
    Photochemistry and photobiology, 2001, Volume: 74, Issue:2

    Topics: Humans; Hydrogen Bonding; In Vitro Techniques; Oxygen; Perylene; Phenol; Photochemistry; Photochemotherapy; Photosensitizing Agents; Quinones; Singlet Oxygen; Spectrometry, Fluorescence; Spectrophotometry; Superoxides

2001
Hypericin and hypocrellin induced apoptosis in human mucosal carcinoma cells.
    Journal of photochemistry and photobiology. B, Biology, 2001, Dec-01, Volume: 65, Issue:1

    Topics: Anthracenes; Antineoplastic Agents; Apoptosis; Caspase 3; Caspases; Cell Line; Cell Membrane; Cell Size; Cell Survival; DNA, Neoplasm; Enzyme Activation; Humans; Mucous Membrane; Nasopharyngeal Neoplasms; Perylene; Phenol; Phosphatidylserines; Photosensitizing Agents; Poly(ADP-ribose) Polymerases; Quinones; Tumor Cells, Cultured

2001
Photodynamic therapy induced Fas-mediated apoptosis in human carcinoma cells.
    International journal of molecular medicine, 2002, Volume: 9, Issue:3

    Topics: Apoptosis; Carcinoma; Caspase 3; Caspases; Cytochrome c Group; Fas Ligand Protein; fas Receptor; Humans; Membrane Glycoproteins; Membrane Potentials; Mitochondria; Nasopharyngeal Neoplasms; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Quinones; Tumor Cells, Cultured

2002
Hypocrellins and Hypericin induced apoptosis in human tumor cells: a possible role of hydrogen peroxide.
    International journal of molecular medicine, 2002, Volume: 9, Issue:5

    Topics: Anthracenes; Apoptosis; Caspase 3; Caspases; Cytochrome c Group; DNA Fragmentation; Enzyme Activation; Flow Cytometry; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Membrane Potentials; Microscopy, Electron; Mitochondria; Perylene; Phenol; Photosensitizing Agents; Poly(ADP-ribose) Polymerases; Quinones; Reactive Oxygen Species; Tumor Cells, Cultured

2002
Potentiation of hypericin and hypocrellin-induced phototoxicity by omeprazole.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 1999, Volume: 6, Issue:5

    Topics: Anthracenes; Antineoplastic Agents; Antiviral Agents; Cell Survival; Drug Synergism; HL-60 Cells; Humans; Omeprazole; Perylene; Phenol; Photosensitizing Agents; Quinones

1999
Efficacy of hypocrellin pharmacokinetics in phototherapy.
    International journal of oncology, 2002, Volume: 21, Issue:6

    Topics: Apoptosis; Apoptotic Protease-Activating Factor 1; Bambusa; bcl-2-Associated X Protein; Blotting, Western; Cytochrome c Group; Drugs, Chinese Herbal; Humans; Immunoenzyme Techniques; Lysosomes; Microscopy, Confocal; Mitochondria; Neoplasms; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Quinones; Subcellular Fractions; Tumor Cells, Cultured

2002
Two-photon excitation studies of hypocrellins for photodynamic therapy.
    Journal of photochemistry and photobiology. B, Biology, 2002, Volume: 68, Issue:2-3

    Topics: Models, Molecular; Molecular Conformation; Perylene; Phenol; Photochemotherapy; Photons; Photosensitizing Agents; Quinones; Spectrometry, Fluorescence; Spectrophotometry

2002
First synthesis of methylated hypocrellin and its fluorescent excited state: a cautionary tale.
    The Journal of organic chemistry, 2003, Mar-07, Volume: 68, Issue:5

    Topics: Mass Spectrometry; Methane; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Perylene; Phenol; Quinones; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet

2003
Photodynamic inhibitory effects of three perylenequinones on human colorectal carcinoma cell line and primate embryonic stem cell line.
    World journal of gastroenterology, 2003, Volume: 9, Issue:3

    Topics: Animals; Carcinoma; Cell Line; Colorectal Neoplasms; Embryo, Mammalian; Humans; Macaca mulatta; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Quinones; Stem Cells

2003
[Study on the detaining effect of hypocrelin a in the cancer cell using microspectrum].
    Guang pu xue yu guang pu fen xi = Guang pu, 2001, Volume: 21, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Lymphoma; Mice; Perylene; Phenol; Photosensitizing Agents; Quinones; Spectrum Analysis; Tumor Cells, Cultured

2001
Synthesis and characterization of three novel amphiphilic aminated hypocrellins as photodynamic therapeutic agents.
    Photochemistry and photobiology, 2003, Volume: 78, Issue:4

    Topics: Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Quinones; Reactive Oxygen Species; Spectrometry, Fluorescence

2003
Photodynamic treatment and H2O2-induced oxidative stress result in different patterns of cellular protein oxidation.
    European journal of biochemistry, 2003, Volume: 270, Issue:24

    Topics: Animals; Apoptosis; Blotting, Western; Electrophoresis, Gel, Two-Dimensional; Fibroblasts; Humans; Hydrogen Peroxide; Light; Microscopy, Confocal; Microscopy, Fluorescence; Oxidative Stress; Oxygen; Perylene; Phenol; Photochemotherapy; Quinones; Rats; Reactive Oxygen Species; Tyrosine

2003
Studies on the synthesis of two hydrophilic hypocrellin derivatives with enhanced absorption in the red spectral region and on their photogeneration of O2*- and O2(1(delta)g).
    Journal of photochemistry and photobiology. B, Biology, 2003, Oct-15, Volume: 71, Issue:1-3

    Topics: Perylene; Phenol; Photochemistry; Quinones; Spectrum Analysis

2003
Inhibitory effect of hypocrellin A on protein kinase C in liver and skeletal muscle of obese Zucker rats.
    The American journal of Chinese medicine, 2003, Volume: 31, Issue:6

    Topics: Animals; Antineoplastic Agents; Diabetes Mellitus; Drugs, Chinese Herbal; Enzyme Activation; Insulin Resistance; Liver; Muscle, Skeletal; Obesity; Perylene; Phenol; Protein Kinase C; Quinones; Rats; Rats, Zucker

2003
Hypocrellin derivative with improvements of red absorption and active oxygen species generation.
    Bioorganic & medicinal chemistry letters, 2004, Mar-22, Volume: 14, Issue:6

    Topics: Dihematoporphyrin Ether; Electron Spin Resonance Spectroscopy; Nuclear Magnetic Resonance, Biomolecular; Perylene; Phenol; Photosensitizing Agents; Quinones; Reactive Oxygen Species

2004
Reduction of high glucose and phorbol-myristate-acetate-induced endothelial cell permeability by protein kinase C inhibitors LY379196 and hypocrellin A.
    Biochemical pharmacology, 2004, Mar-01, Volume: 67, Issue:5

    Topics: Biological Transport; Cell Membrane Permeability; Cells, Cultured; Drug Interactions; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression; Glucose; Humans; Isoenzymes; Mesylates; Perylene; Phenol; Protein Kinase C; Pyrroles; Quinones; Tetradecanoylphorbol Acetate

2004
Antimicrobial and antileishmanial activities of hypocrellins A and B.
    Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:11

    Topics: Animals; Anti-Infective Agents; Antiprotozoal Agents; Bacteria; Fungi; Leishmania donovani; Microbial Sensitivity Tests; Opportunistic Infections; Perylene; Phenol; Quinones

2004
High glucose-induced human umbilical vein endothelial cell hyperpermeability is dependent on protein kinase C activation and independent of the Ca2+-nitric oxide signalling pathway.
    Clinical and experimental pharmacology & physiology, 2005, Volume: 32, Issue:9

    Topics: Calcium Signaling; Capillary Permeability; Cells, Cultured; Endothelial Cells; Enzyme Activation; Glucose; Histamine; Humans; Mesylates; Nitric Oxide; omega-N-Methylarginine; Permeability; Perylene; Phenol; Protein Kinase C; Pyrroles; Quinones

2005
Anion of hypericin is crucial to understanding the photosensitive features of the pigment.
    Bioorganic & medicinal chemistry letters, 2006, Mar-01, Volume: 16, Issue:5

    Topics: Anions; Anthracenes; Electrons; Molecular Structure; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Pigments, Biological; Quinones; Singlet Oxygen

2006
[Studies on liquid fermentation of anamorph of Shiraia bambusicola].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2005, Volume: 28, Issue:12

    Topics: Analysis of Variance; Ascomycota; Culture Media; Fermentation; Hydrogen-Ion Concentration; Hyphae; Nitrogen; Perylene; Phenol; Quinones; Temperature

2005
Effect of chelation to lanthanum ions on the photodynamic properties of hypocrellin A.
    The journal of physical chemistry. B, 2005, Oct-20, Volume: 109, Issue:41

    Topics: Aerobiosis; Anaerobiosis; Ascomycota; Chelating Agents; Chemical Phenomena; Chemistry, Physical; DNA; Electron Spin Resonance Spectroscopy; Ethidium; Hydroxylation; Lanthanum; Luminescence; Oxygen; Perylene; Phenol; Photochemistry; Photolysis; Photosensitizing Agents; Quinones; Spectrophotometry, Ultraviolet; Superoxides

2005
Photodynamic properties of hypocrellin A, complexes with rare Earth trivalent ions: role of the excited state energies of the metal ions.
    The journal of physical chemistry. B, 2007, Mar-15, Volume: 111, Issue:10

    Topics: Benzoquinones; Cations; DNA; Hydroxyl Radical; Metals, Rare Earth; Nucleic Acid Denaturation; Perylene; Phenol; Photochemistry; Photochemotherapy; Photosensitizing Agents; Quinones; Reactive Oxygen Species; Spectrum Analysis; Static Electricity; Superoxides; Water

2007
[Study on interaction between hypocrellin A and hemoglobin or myoglobin using synchronous fluorescence spectra].
    Guang pu xue yu guang pu fen xi = Guang pu, 2006, Volume: 26, Issue:12

    Topics: Hemoglobins; Molecular Structure; Myoglobin; Perylene; Phenol; Quinones; Spectrometry, Fluorescence

2006
Apoptosis induced by photosensitizers (Perylquinone derivatives) in human carcinoma cells: a possible relevance to photodynamic therapy.
    Asian journal of surgery, 2002, Volume: 25, Issue:1

    Topics: Apoptosis; Carcinoma; Cell Culture Techniques; Cell Line, Tumor; Colon; Humans; Mucous Membrane; Nasopharyngeal Neoplasms; Perylene; Phenol; Photosensitizing Agents; Quinones; Urinary Bladder

2002
Effects of hypocrellin A on expression of vascular endothelial growth factor and endothelin-1 in human umbilical endothelial cells.
    The American journal of Chinese medicine, 2007, Volume: 35, Issue:4

    Topics: Cells, Cultured; Drugs, Chinese Herbal; Endothelin-1; Endothelium, Vascular; Enzyme Activation; Glucose; Humans; Hypocreales; Mannitol; Perylene; Phenol; Protein Kinase C; Quinones; RNA, Messenger; Umbilical Cord; Vascular Endothelial Growth Factor A

2007
Photosensitizer effects on cancerous cells: a combined study using synchrotron infrared and fluorescence microscopies.
    Biochimica et biophysica acta, 2008, Volume: 1780, Issue:5

    Topics: Cell Nucleus; Cytoplasm; HeLa Cells; Humans; Infrared Rays; Intracellular Space; Light; Microscopy; Microscopy, Fluorescence; Molecular Structure; Neoplasms; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Principal Component Analysis; Quinones; Spectrophotometry, Infrared; Synchrotrons

2008
Dynamic stereochemistry transfer in a transannular aldol reaction: total synthesis of hypocrellin A.
    Angewandte Chemie (International ed. in English), 2008, Volume: 47, Issue:36

    Topics: Antineoplastic Agents; Molecular Conformation; Perylene; Phenol; Photosensitizing Agents; Quinones; Stereoisomerism

2008
Isolation and identification of a new hypocrellin A-producing strain Shiraia sp. SUPER-H168.
    Microbiological research, 2009, Volume: 164, Issue:1

    Topics: Ascomycota; Bambusa; China; DNA, Fungal; DNA, Ribosomal; Fermentation; Molecular Sequence Data; Perylene; Phenol; Phylogeny; Quinones; RNA, Ribosomal, 18S

2009
Spectroscopic studies on the interaction of hypocrellin A and hemoglobin.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2009, Volume: 72, Issue:1

    Topics: Electron Spin Resonance Spectroscopy; Hemoglobins; Kinetics; Light; Perylene; Phenol; Quinones; Solutions; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Spectrum Analysis

2009
High-yield hypocrellin A production in solid-state fermentation by Shiraia sp. SUPER-H168.
    Applied biochemistry and biotechnology, 2010, Volume: 160, Issue:8

    Topics: Antiviral Agents; Ascomycota; Bioreactors; Carbon; Cell Culture Techniques; Crops, Agricultural; Drugs, Chinese Herbal; Fermentation; Glucose; Hydrogen-Ion Concentration; Industrial Microbiology; Molecular Structure; Nitrates; Nitrogen; Particle Size; Perylene; Phenol; Quinones; Temperature

2010
Synthesis of the cores of hypocrellin and shiraiachrome: diastereoselective 1,8-diketone aldol cyclization.
    The Journal of organic chemistry, 2010, Jan-01, Volume: 75, Issue:1

    Topics: Aldehydes; Catalysis; Cyclization; Ketones; Molecular Structure; Perylene; Phenol; Quinones; Stereoisomerism

2010
Perylenequinone natural products: total synthesis of hypocrellin A.
    The Journal of organic chemistry, 2010, Jan-01, Volume: 75, Issue:1

    Topics: Biological Products; Catalysis; Cyclization; Molecular Structure; Perylene; Phenol; Quinones; Stereoisomerism

2010
A new sol-gel silica nanovehicle preparation for photodynamic therapy in vitro.
    International journal of pharmaceutics, 2010, Feb-15, Volume: 386, Issue:1-2

    Topics: Apoptosis; Biological Transport; Cell Survival; Chemical Precipitation; Chemistry, Pharmaceutical; Drug Carriers; Drug Compounding; Drug Stability; Gels; HeLa Cells; Humans; Hydrogen Bonding; Membrane Potential, Mitochondrial; Microscopy, Electron, Transmission; Mitochondria; Nanoparticles; Particle Size; Perylene; Pharmaceutical Vehicles; Phenol; Photochemotherapy; Photosensitizing Agents; Propylamines; Quinones; Reactive Oxygen Species; Reproducibility of Results; Silanes; Singlet Oxygen; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Technology, Pharmaceutical; Time Factors

2010
Mitochondria-targeting photosensitizer-encapsulated amorphous nanocage as a bimodal reagent for drug delivery and biodiagnose in vitro.
    Biomedical microdevices, 2010, Volume: 12, Issue:4

    Topics: Biological Transport; Drug Carriers; HeLa Cells; Humans; Hydrogen Bonding; Indicators and Reagents; Intracellular Space; Microscopy, Electron, Transmission; Mitochondria; Models, Molecular; Molecular Conformation; Perylene; Phenol; Photobleaching; Photochemotherapy; Photosensitizing Agents; Quinones; Silanes; Silicon Dioxide; Singlet Oxygen; Spectroscopy, Fourier Transform Infrared

2010
Toxicity and phototoxicity of Hypocrellin A on malignant human cell lines, evidence of a synergistic action of photodynamic therapy with Imatinib mesylate.
    Journal of photochemistry and photobiology. B, Biology, 2010, May-03, Volume: 99, Issue:2

    Topics: Antineoplastic Agents; Benzamides; Cell Line, Tumor; Drug Synergism; Drug Therapy, Combination; HeLa Cells; Humans; Imatinib Mesylate; K562 Cells; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Piperazines; Pyrimidines; Quinones

2010
A nanoencapsulated hypocrellin A prepared by an improved microemulsion method for photodynamic treatment.
    Journal of materials science. Materials in medicine, 2010, Volume: 21, Issue:7

    Topics: Antineoplastic Agents; Drug Carriers; Female; HeLa Cells; Humans; Nanoparticles; Nanotechnology; Perylene; Phenol; Photochemotherapy; Quinones; Silicon Dioxide; Singlet Oxygen

2010
[Cluster analysis on hypocrellin A content in anamorphs of Shiraia bambusicola].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2010, Volume: 35, Issue:8

    Topics: Ascomycota; Cluster Analysis; Mycelium; Perylene; Phenol; Pigmentation; Quinones; Spectrophotometry, Ultraviolet

2010
Delivering a hydrophobic anticancer drug for photodynamic therapy by amorphous formulation.
    Bioorganic & medicinal chemistry letters, 2010, Nov-01, Volume: 20, Issue:21

    Topics: Benzimidazoles; Cell Death; Chemistry, Pharmaceutical; Coloring Agents; DNA, Mitochondrial; Dose-Response Relationship, Drug; Drug Delivery Systems; Fluorescent Dyes; HeLa Cells; Humans; Micelles; Mitochondria; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Polysorbates; Quinones; Spectrometry, Fluorescence; Surface-Active Agents; Tetrazolium Salts; Thiazoles; X-Ray Diffraction

2010
A molecular logic gate for the highly selective recognition of pyrophosphate with a hypocrellin A-Zn(II) complex.
    The Analyst, 2010, Volume: 135, Issue:11

    Topics: Diphosphates; Fluorescence; Organometallic Compounds; Perylene; Phenol; Quinones; Zinc

2010
Photodynamic antimicrobial activity of hypocrellin A.
    Journal of photochemistry and photobiology. B, Biology, 2011, Apr-04, Volume: 103, Issue:1

    Topics: Anti-Infective Agents; Bacteria; Free Radical Scavengers; Light; Microbial Viability; Perylene; Phenol; Quinones; Reactive Oxygen Species

2011
Induction of hypocrellin production by Triton X-100 under submerged fermentation with Shiraia sp. SUPER-H168.
    New biotechnology, 2011, Volume: 28, Issue:6

    Topics: Ascomycota; Detergents; Octoxynol; Perylene; Phenol; Quinones

2011
Graphene oxide noncovalent photosensitizer and its anticancer activity in vitro.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2011, Oct-17, Volume: 17, Issue:43

    Topics: Antineoplastic Agents; Drug Delivery Systems; Graphite; HeLa Cells; Humans; Light; Molecular Structure; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Quinones; Singlet Oxygen; Water

2011
Development of an HPLC method to analyze and prepare elsinochrome C and hypocrellin A in the submerged fermentation broth of Shiria sp. SUPER-H168.
    Biomedical chromatography : BMC, 2012, Volume: 26, Issue:6

    Topics: Ascomycota; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Fermentation; Limit of Detection; Linear Models; Perylene; Phenol; Polycyclic Compounds; Quinones; Reproducibility of Results

2012
Cerebrospinal fluid hypocretin (orexin) levels are elevated by play but are not raised by exercise and its associated heart rate, blood pressure, respiration or body temperature changes.
    Archives italiennes de biologie, 2011, Nov-07, Volume: 149, Issue:4

    Topics: Analysis of Variance; Animals; Blood Pressure; Body Temperature; Dogs; Exercise Test; Male; Perylene; Phenol; Physical Conditioning, Animal; Play and Playthings; Quinones; Radioimmunoassay; Respiration

2011
Synthesis and photophysical properties of a supramolecular host-guest assembly constructed by fullerenes and tryptamine modified hypocrellin.
    The journal of physical chemistry. B, 2012, Feb-23, Volume: 116, Issue:7

    Topics: Coordination Complexes; Electrochemical Techniques; Fullerenes; Perylene; Phenol; Quinones; Spectroscopy, Near-Infrared; Tryptamines

2012
[Simultaneous determination of hypocrellin A, hypocrellin B, and hypocrellin C by HPLC].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2012, Volume: 37, Issue:1

    Topics: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Hypocreales; Perylene; Phenol; Quinones

2012
Synthesis of vanadyl-hypocrellin A complex and its photodynamic properties research.
    Bioorganic & medicinal chemistry letters, 2012, Aug-01, Volume: 22, Issue:15

    Topics: Apoptosis; DNA Damage; HeLa Cells; Humans; Light; Perylene; Phenol; Photosensitizing Agents; Quinones; Solubility; Vanadates; Water

2012
Antibacterial activity of hypocrellin A against Staphylococcus aureus.
    World journal of microbiology & biotechnology, 2012, Volume: 28, Issue:11

    Topics: Anti-Bacterial Agents; Cell Membrane Permeability; Culture Media; Enzyme Inhibitors; Microscopy, Electron, Scanning; Oxidoreductases; Perylene; Phenol; Quinones; Staphylococcus aureus

2012
Hypocrellin-loaded gold nanocages with high two-photon efficiency for photothermal/photodynamic cancer therapy in vitro.
    ACS nano, 2012, Sep-25, Volume: 6, Issue:9

    Topics: Antineoplastic Agents; Apoptosis; Diffusion; Gold; HeLa Cells; Humans; Metal Nanoparticles; Nanocapsules; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Quinones

2012
Study on the conformation changes of Lysozyme induced by Hypocrellin A: the mechanism investigation.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2012, Volume: 97

    Topics: Animals; Chickens; Circular Dichroism; Energy Transfer; Muramidase; Perylene; Phenol; Protein Structure, Secondary; Quinones; Solutions; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Thermogravimetry; Time Factors

2012
External heavy-atomic construction of photosensitizer nanoparticles for enhanced in vitro photodynamic therapy of cancer.
    The journal of physical chemistry. B, 2012, Oct-25, Volume: 116, Issue:42

    Topics: Antineoplastic Agents; Cell Death; Cell Survival; Drug Delivery Systems; Gold; HeLa Cells; Humans; Nanoparticles; Neoplasms; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Platinum; Quinones; Silicon Dioxide; Singlet Oxygen; Structure-Activity Relationship; Tumor Cells, Cultured

2012
Effects of microbial elicitor on production of hypocrellin by Shiraia bambusicola.
    Folia microbiologica, 2013, Volume: 58, Issue:4

    Topics: Anti-Infective Agents; Ascomycota; Biotechnology; Culture Media; DNA, Fungal; DNA, Ribosomal Spacer; Fermentation; Molecular Sequence Data; Perylene; Phenol; Quinones; Sequence Analysis, DNA; Trametes

2013
Complexation of Hypocrellin A with Al3+ in water solution and the photodynamic therapy study.
    Bioorganic & medicinal chemistry letters, 2013, Mar-15, Volume: 23, Issue:6

    Topics: Aluminum; Antineoplastic Agents; Cell Shape; Coordination Complexes; DNA; Female; HeLa Cells; Humans; Ions; Light; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Quinones; Singlet Oxygen; Uterine Cervical Neoplasms; Water

2013
Interactions of CT-DNA with Hypocrellin A and its Al(3+)-Hypocrellin A complex.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2013, May-15, Volume: 109

    Topics: Aluminum; Animals; Cattle; Circular Dichroism; Coordination Complexes; DNA; Drugs, Chinese Herbal; Nucleic Acid Conformation; Perylene; Phenol; Photosensitizing Agents; Quinones; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet

2013
Regulated forms of cell death are induced by the photodynamic action of the fluorogenic substrate, Hypocrellin B-acetate.
    Journal of photochemistry and photobiology. B, Biology, 2013, Aug-05, Volume: 125

    Topics: Apoptosis; Autophagy; Fluorescent Dyes; HeLa Cells; Humans; Light; Necrosis; Perylene; Phenol; Photosensitizing Agents; Quinones

2013
Internal heavy atom effect of Au(III) and Pt(IV) on hypocrellin A for enhanced in vitro photodynamic therapy of cancer.
    Bioorganic & medicinal chemistry letters, 2013, Oct-01, Volume: 23, Issue:19

    Topics: Cell Survival; Coordination Complexes; Gold; HeLa Cells; Humans; Metals, Heavy; Microscopy, Fluorescence; Models, Biological; Molecular Structure; Neoplasms; Perylene; Phenol; Photosensitizing Agents; Platinum; Quinones; Solubility; Spectroscopy, Fourier Transform Infrared

2013
A new near infrared photosensitizing nanoplatform containing blue-emitting up-conversion nanoparticles and hypocrellin A for photodynamic therapy of cancer cells.
    Nanoscale, 2013, Dec-07, Volume: 5, Issue:23

    Topics: Cell Line, Tumor; Cell Survival; Contrast Media; Fluorides; Gadolinium; HeLa Cells; Humans; Infrared Rays; Magnetic Resonance Imaging; Metal Nanoparticles; Neoplasms; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Polysorbates; Quinones; Radiography; Singlet Oxygen; Yttrium

2013
Spectroscopic studies on the interaction of Ga3+-hypocrellin A with myoglobin.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2014, Volume: 121

    Topics: Absorption; Circular Dichroism; Energy Transfer; Gallium; Kinetics; Myoglobin; Perylene; Phenol; Protein Structure, Secondary; Quinones; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Temperature; Time Factors

2014
Combination of chemotherapy and photodynamic therapy using graphene oxide as drug delivery system.
    Journal of photochemistry and photobiology. B, Biology, 2014, Jun-05, Volume: 135

    Topics: Antineoplastic Agents; Biological Transport; Camptothecin; Cell Line, Tumor; Drug Carriers; Graphite; Humans; Irinotecan; Oxides; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Quinones; Singlet Oxygen

2014
Nitric oxide mediates hypocrellin accumulation induced by fungal elicitor in submerged cultures of Shiraia bambusicola.
    Biotechnology letters, 2015, Volume: 37, Issue:1

    Topics: Ascomycota; Cell Culture Techniques; Fungal Proteins; Nitric Oxide; Perylene; Phenol; Quinones; Salicylic Acid

2015
Dual-modal imaging and photodynamic therapy using upconversion nanoparticles for tumor cells.
    The Analyst, 2014, Dec-21, Volume: 139, Issue:24

    Topics: Contrast Media; Fluorides; Gadolinium; HEK293 Cells; HeLa Cells; Humans; Magnetic Resonance Imaging; Microscopy, Confocal; Nanoparticles; Neoplasms; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Quinones; Silicon Dioxide; Yttrium

2014
Multicolor imaging and the anticancer effect of a bifunctional silica nanosystem based on the complex of graphene quantum dots and hypocrellin A.
    Chemical communications (Cambridge, England), 2015, Volume: 51, Issue:2

    Topics: Antineoplastic Agents; Graphite; HeLa Cells; Humans; Nanoparticles; Neoplasms; Optical Imaging; Perylene; Phenol; Photochemotherapy; Quantum Dots; Quinones; Silicon Dioxide

2015
High-efficiency biosynthesis of hypocrellin A in Shiraia sp. using gamma-ray mutagenesis.
    Applied microbiology and biotechnology, 2016, Volume: 100, Issue:11

    Topics: Ascomycota; Dose-Response Relationship, Radiation; Gamma Rays; Industrial Microbiology; Mutagenesis; Perylene; Phenol; Quinones; Sasa; Seeds

2016
Reference genes selection and relative expression analysis from Shiraia sp. SUPER-H168 productive of hypocrellin.
    Gene, 2016, Apr-10, Volume: 580, Issue:1

    Topics: Antiviral Agents; Ascomycota; Electron Transport Complex IV; Gene Expression Profiling; Glyceraldehyde-3-Phosphate Dehydrogenases; Mixed Function Oxygenases; Perylene; Phenol; Polyketide Synthases; Protein O-Methyltransferase; Quinones; Real-Time Polymerase Chain Reaction; RNA, Ribosomal, 18S; Tubulin

2016
De Novo Transcriptome Assembly in Shiraia bambusicola to Investigate Putative Genes Involved in the Biosynthesis of Hypocrellin A.
    International journal of molecular sciences, 2016, Feb-27, Volume: 17, Issue:3

    Topics: Ascomycota; Genes, Fungal; Perylene; Phenol; Quinones; Transcriptome

2016
808 nm Light-triggered and hyaluronic acid-targeted dual-photosensitizers nanoplatform by fully utilizing Nd(3+)-sensitized upconversion emission with enhanced anti-tumor efficacy.
    Biomaterials, 2016, Volume: 101

    Topics: Animals; Apoptosis; Drug Delivery Systems; Female; Fluorides; HeLa Cells; Humans; Hyaluronic Acid; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neodymium; Neoplasms; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Quinones; Reactive Oxygen Species; Titanium; Ultraviolet Rays; Yttrium

2016
Four-photon-excited fluorescence resonance energy transfer in an aqueous system from ZnSe:Mn/ZnS quantum dots to hypocrellin A.
    Optics express, 2016, Aug-22, Volume: 24, Issue:17

    Topics: Fluorescence Resonance Energy Transfer; Perylene; Phenol; Photons; Quantum Dots; Quinones; Selenium Compounds; Sulfides; Zinc Compounds

2016
Adaptive Responses to Oxidative Stress in the Filamentous Fungal Shiraia bambusicola.
    Molecules (Basel, Switzerland), 2016, Aug-24, Volume: 21, Issue:9

    Topics: Adaptation, Physiological; Ascomycota; Biomass; Hydrogen Peroxide; Oxidative Stress; Perylene; Phenol; Quinones

2016
Characterization of a major facilitator superfamily transporter in Shiraia bambusicola.
    Research in microbiology, 2017, Volume: 168, Issue:7

    Topics: Ascomycota; CRISPR-Cas Systems; Membrane Transport Proteins; Mutation; Perylene; Phenol; Quinones; Reactive Oxygen Species; Sasa

2017
Enhanced production of hypocrellin A by ultrasound stimulation in submerged cultures of Shiraia bambusicola.
    Ultrasonics sonochemistry, 2017, Volume: 38

    Topics: Ascomycota; Cell Membrane; Culture Techniques; Immersion; Perylene; Phenol; Quinones; Ultrasonic Waves

2017
Transcriptomic responses involved in enhanced production of hypocrellin A by addition of Triton X-100 in submerged cultures of Shiraia bambusicola.
    Journal of industrial microbiology & biotechnology, 2017, Volume: 44, Issue:10

    Topics: Ascomycota; Fermentation; Gene Expression Profiling; Mycelium; Octoxynol; Perylene; Phenol; Quinones; Surface-Active Agents; Transcriptome

2017
Genome editing in Shiraia bambusicola using CRISPR-Cas9 system.
    Journal of biotechnology, 2017, Oct-10, Volume: 259

    Topics: Ascomycota; CRISPR-Cas Systems; Fungal Proteins; Gene Editing; Perylene; Phenol; Polyketide Synthases; Quinones; Sasa; Virulence Factors

2017
Sonodynamic bactericidal efficacy of hypocrellin A and B against methicillin-resistant Staphylococcus aureus.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2017, Volume: 23 Suppl 5, Issue:4

    Topics: Methicillin-Resistant Staphylococcus aureus; Perylene; Phenol; Quinones

2017
Photo-tearable tape close-wrapped upconversion nanocapsules for near-infrared modulated efficient siRNA delivery and therapy.
    Biomaterials, 2018, Volume: 163

    Topics: Animals; Cell Cycle Proteins; Cell Survival; Drug Liberation; Female; Genetic Therapy; HeLa Cells; Humans; Lanthanoid Series Elements; Mice, Nude; Nanocapsules; Particle Size; Perylene; Phenol; Photochemical Processes; Photosensitizing Agents; Polo-Like Kinase 1; Polyethylene Glycols; Porosity; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Quinones; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Silicon Dioxide; Ultraviolet Rays

2018
Improved hypocrellin A production in Shiraia bambusicola by light-dark shift.
    Journal of photochemistry and photobiology. B, Biology, 2018, Volume: 182

    Topics: Ascomycota; Gene Expression Regulation, Fungal; Industrial Microbiology; Light; Mycelium; Perylene; Phenol; Photoperiod; Quinones; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction

2018
Enhanced hypocrellin production of Shiraia sp. SUPER-H168 by overexpression of alpha-amylase gene.
    PloS one, 2018, Volume: 13, Issue:5

    Topics: alpha-Amylases; Ascomycota; Biosynthetic Pathways; Cloning, Molecular; DNA, Fungal; Fermentation; Fungal Proteins; Genes, Fungal; Glucose; Perylene; Phenol; Photosensitizing Agents; Quinones; Up-Regulation

2018
Influences of light on growth, reproduction and hypocrellin production by Shiraia sp. SUPER-H168.
    Archives of microbiology, 2018, Volume: 200, Issue:8

    Topics: Ascomycota; Biofilms; Hyphae; Light; Microscopy, Electron, Transmission; Perylene; Phenol; Quinones

2018
Characterisation of a monooxygenase in Shiraia bambusicola.
    Microbiology (Reading, England), 2018, Volume: 164, Issue:9

    Topics: Ascomycota; Cloning, Molecular; Clustered Regularly Interspaced Short Palindromic Repeats; CRISPR-Associated Protein 9; Decarboxylation; Gene Deletion; Gene Expression; Gene Expression Profiling; Genetic Complementation Test; Hydroxylation; Mixed Function Oxygenases; Perylene; Phenol; Pichia; Quinones; Salicylates

2018
Enhanced Production of Hypocrellin A in Submerged Cultures of Shiraia bambusicola by Red Light.
    Photochemistry and photobiology, 2019, Volume: 95, Issue:3

    Topics: Ascomycota; Biosynthetic Pathways; Cell Membrane Permeability; Genes, Fungal; Light; Molecular Sequence Annotation; Mycelium; Perylene; Phenol; Photosensitizing Agents; Quinones; Transcriptome

2019
Molecular evidence for better efficacy of hypocrellin A and oleanolic acid combination in suppression of HCC growth.
    European journal of pharmacology, 2019, Jan-05, Volume: 842

    Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Movement; Cell Proliferation; Cell Survival; Drug Synergism; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Oleanolic Acid; Perylene; Phenol; Quinones; Transcription Factors

2019
Gentic overexpression increases production of hypocrellin A in Shiraia bambusicola S4201.
    Journal of microbiology (Seoul, Korea), 2019, Volume: 57, Issue:2

    Topics: Ascomycota; Biosynthetic Pathways; Gene Expression Regulation, Fungal; Gene Fusion; Genes, Fungal; Genetic Vectors; Methyltransferases; Mixed Function Oxygenases; Perylene; Phenol; Quinones; Transformation, Genetic

2019
Biodegradable Natural Product-Based Nanoparticles for Near-Infrared Fluorescence Imaging-Guided Sonodynamic Therapy.
    ACS applied materials & interfaces, 2019, May-22, Volume: 11, Issue:20

    Topics: Animals; HeLa Cells; Humans; Mice, Nude; Nanoparticles; Neoplasms, Experimental; Optical Imaging; Perylene; Phenol; Quinones; Theranostic Nanomedicine; Ultrasonic Therapy; Xenograft Model Antitumor Assays

2019
Inducing perylenequinone production from a bambusicolous fungus Shiraia sp. S9 through co-culture with a fruiting body-associated bacterium Pseudomonas fulva SB1.
    Microbial cell factories, 2019, Jul-05, Volume: 18, Issue:1

    Topics: Ascomycota; Coculture Techniques; Fruiting Bodies, Fungal; Fungal Proteins; Microbial Interactions; Perylene; Phenol; Polyketide Synthases; Pseudomonas; Quinones; Spores, Fungal

2019
Evaluation of hypocrellin A-loaded lipase sensitive polymer micelles for intervening methicillin-resistant Staphylococcus Aureus antibiotic-resistant bacterial infection.
    Materials science & engineering. C, Materials for biological applications, 2020, Volume: 106

    Topics: Animals; Anti-Bacterial Agents; Drug Carriers; Female; Lipase; Methicillin-Resistant Staphylococcus aureus; Mice; Micelles; Microbial Sensitivity Tests; Perylene; Phenol; Photochemotherapy; Polymers; Quinones

2020
Natural-Origin Hypocrellin-HSA Assembly for Highly Efficient NIR Light-Responsive Phototheranostics against Hypoxic Tumors.
    ACS applied materials & interfaces, 2019, Dec-04, Volume: 11, Issue:48

    Topics: Animals; Cell Line, Tumor; Female; Humans; Hyperthermia, Induced; Infrared Rays; Mice; Mice, Nude; Nanoparticles; Neoplasms; Perylene; Phenol; Photochemotherapy; Quinones; Serum Albumin; Theranostic Nanomedicine

2019
Global identification of alternative splicing in Shiraia bambusicola and analysis of its regulation in hypocrellin biosynthesis.
    Applied microbiology and biotechnology, 2020, Volume: 104, Issue:1

    Topics: Alternative Splicing; Antifungal Agents; Ascomycota; Biosynthetic Pathways; Fermentation; Gene Expression Regulation, Fungal; Hydrogen Peroxide; Multigene Family; Perylene; Phenol; Quinones; Secondary Metabolism; Stress, Physiological

2020
Inhibition of ROS-NF-κB-dependent autophagy enhances Hypocrellin A united LED red light-induced apoptosis in squamous carcinoma A431 cells.
    Cellular signalling, 2020, Volume: 69

    Topics: Antineoplastic Agents; Apoptosis; Autophagy; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Humans; NF-kappa B; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Quinones; Reactive Oxygen Species; Skin Neoplasms

2020
Antifungal activity of hypocrellin compounds and their synergistic effects with antimicrobial agents against Candida albicans.
    Microbial biotechnology, 2021, Volume: 14, Issue:2

    Topics: Anti-Infective Agents; Antifungal Agents; Candida albicans; Microbial Sensitivity Tests; Perylene; Phenol; Quinones

2021
Near-Infrared Hypocrellin Derivatives for Synergistic Photodynamic and Photothermal Therapy.
    Chemistry, an Asian journal, 2020, Nov-02, Volume: 15, Issue:21

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Female; Infrared Rays; Mammary Neoplasms, Experimental; Mice; Optical Imaging; Perylene; Phenol; Photosensitizing Agents; Photothermal Therapy; Quinones; Theranostic Nanomedicine

2020
Modular engineering of Shiraia bambusicola for hypocrellin production through an efficient CRISPR system.
    International journal of biological macromolecules, 2020, Dec-15, Volume: 165, Issue:Pt A

    Topics: Ascomycota; CRISPR-Cas Systems; Gene Editing; Perylene; Phenol; Quinones

2020
Purification of hypocrellins from Shiraia bambusicola by coordinated high-speed countercurrent chromatography using cupric chloride as a complexing agent.
    Journal of separation science, 2021, Volume: 44, Issue:7

    Topics: Ascomycota; Copper; Countercurrent Distribution; Molecular Structure; Perylene; Phenol; Quinones

2021
Nitric oxide regulates perylenequinones biosynthesis in Shiraia bambusicola S4201 induced by hydrogen peroxide.
    Scientific reports, 2021, 01-27, Volume: 11, Issue:1

    Topics: Ascomycota; Hydrogen Peroxide; Nitric Oxide; Perylene; Phenol; Quinones

2021
Antifibrotic effects of Hypocrellin A combined with LED red light irradiation on keloid fibroblasts by counteracting the TGF-β/Smad/autophagy/apoptosis signalling pathway.
    Photodiagnosis and photodynamic therapy, 2021, Volume: 34

    Topics: Apoptosis; Autophagy; Cell Proliferation; Cells, Cultured; Fibroblasts; Humans; Keloid; Light; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Quinones

2021
Nitric oxide donor sodium nitroprusside-induced transcriptional changes and hypocrellin biosynthesis of Shiraia sp. S9.
    Microbial cell factories, 2021, Apr-28, Volume: 20, Issue:1

    Topics: Ascomycota; Biosynthetic Pathways; Mycelium; Nitric Oxide Donors; Nitroprusside; Perylene; Phenol; Quinones; Reactive Oxygen Species; Transcription, Genetic

2021
The signaling role of extracellular ATP in co-culture of Shiraia sp. S9 and Pseudomonas fulva SB1 for enhancing hypocrellin A production.
    Microbial cell factories, 2021, Jul-23, Volume: 20, Issue:1

    Topics: Adenosine Triphosphate; Ascomycota; Cytosol; Perylene; Phenol; Pseudomonas; Quinones; Reactive Oxygen Species; Signal Transduction

2021
Ultrasound responsive self-assembled micelles loaded with hypocrellin for cancer sonodynamic therapy.
    International journal of pharmaceutics, 2021, Oct-25, Volume: 608

    Topics: Cell Line, Tumor; Humans; Micelles; Nanoparticles; Neoplasms; Perylene; Phenol; Quinones; Reactive Oxygen Species

2021
A novel hypocrellin-based assembly for sonodynamic therapy against glioblastoma.
    Journal of materials chemistry. B, 2021, 12-22, Volume: 10, Issue:1

    Topics: Antineoplastic Agents; Biocompatible Materials; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Glioblastoma; Humans; Materials Testing; Molecular Structure; Particle Size; Perylene; Phenol; Quinones; Ultrasonic Therapy; Ultrasonic Waves

2021
Hypocrellin A exerts antitumor effects by inhibiting the FGFR1 signaling pathway in non-small cell lung cancer.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2022, Volume: 97

    Topics: Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Humans; Lung Neoplasms; Mice; Molecular Docking Simulation; Perylene; Phenol; Quinones; Receptor, Fibroblast Growth Factor, Type 1; Signal Transduction; Xenograft Model Antitumor Assays

2022
Biocompatible hypocrellin A-Fe(III) nanoparticles exhibiting efficient photo-activated CDT
    Dalton transactions (Cambridge, England : 2003), 2022, Feb-22, Volume: 51, Issue:8

    Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; Iron; Metal Nanoparticles; Perylene; Phenol; Photochemical Processes; Quinones; Theranostic Nanomedicine

2022
Effects of Blue Light on Hypocrellin A Production in Shiraia Mycelium Cultures.
    Photochemistry and photobiology, 2022, Volume: 98, Issue:6

    Topics: Ascomycota; Light; Mycelium; Perylene; Phenol; Quinones

2022
Temperature-responsive regulation of the fermentation of hypocrellin A by Shiraia bambusicola (GDMCC 60438).
    Microbial cell factories, 2022, Jul-05, Volume: 21, Issue:1

    Topics: Ascomycota; Fermentation; Perylene; Phenol; Quinones; Temperature

2022
Structure characterization of an exopolysaccharide from a Shiraia-associated bacterium and its strong eliciting activity on the fungal hypocrellin production.
    International journal of biological macromolecules, 2023, Jan-31, Volume: 226

    Topics: Ascomycota; Humans; Perylene; Phenol; Photochemotherapy; Quinones

2023
Bamboo polysaccharides elicit hypocrellin A biosynthesis of a bambusicolous fungus Shiraia sp. S9.
    World journal of microbiology & biotechnology, 2023, Oct-13, Volume: 39, Issue:12

    Topics: Fungi; Hydrogen Peroxide; Perylene; Phenol; Polysaccharides; Quinones

2023
Lipopolysaccharides from a Shiraia fruiting body-associated bacterium elicit host fungal hypocrellin A biosynthesis through nitric oxide generation.
    Carbohydrate polymers, 2024, Jan-15, Volume: 324

    Topics: Ascomycota; Gene Expression Profiling; Lipopolysaccharides; Nitric Oxide; Perylene; Phenol

2024