Page last updated: 2024-09-03

hypocrellin a and hypericin

hypocrellin a has been researched along with hypericin in 13 studies

Compound Research Comparison

Studies
(hypocrellin a)
Trials
(hypocrellin a)
Recent Studies (post-2010)
(hypocrellin a)
Studies
(hypericin)
Trials
(hypericin)
Recent Studies (post-2010) (hypericin)
17207298231380

Protein Interaction Comparison

ProteinTaxonomyhypocrellin a (IC50)hypericin (IC50)
Cytochrome P450 3A4Homo sapiens (human)8.7
Corticotropin-releasing factor receptor 1Homo sapiens (human)0.3
Cystathionine beta-synthaseHomo sapiens (human)3.1
Alpha-synucleinHomo sapiens (human)7.5
Glutathione reductaseSaccharomyces cerevisiae S288C3.67
Integrase Human immunodeficiency virus 110
Cysteine protease ATG4BHomo sapiens (human)8.9

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (53.85)18.2507
2000's5 (38.46)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Carpenter, SL; Fehr, MJ; Petrich, JW; Wannemuehler, Y1
Diwu, Z1
Chen, J; Harris, L; Hudson, JB; Towers, GH; Yip, L; Zhou, J1
Carpenter, S; English, DS; Park, J; Petrich, JW; Wannemuehler, Y1
Chaloupka, R; Obsil, T; Plásek, J; Sureau, F1
Das, K; Miskovsky, P; Petrich, JW; Smirnov, AV; Wen, J1
Hájiková, M; Lacková, A; Mirossay, A; Mirossay, L; Mojzis, J; Tóthová, J1
Ali, SM; Chee, SK; Olivo, M; Yuen, GY2
Mirossay, A; Mirossay, L; Miskovský, P; Mojzis, J; Onderková, H; Tóthová, J1
Ji, HF; Shen, L; Zhang, HY1
Chin, W; Olivo, M1

Reviews

2 review(s) available for hypocrellin a and hypericin

ArticleYear
Novel therapeutic and diagnostic applications of hypocrellins and hypericins.
    Photochemistry and photobiology, 1995, Volume: 61, Issue:6

    Topics: Animals; Anthracenes; Antidepressive Agents; Antiviral Agents; Drugs, Chinese Herbal; Humans; Perylene; Phenol; Quinones; Radiation-Sensitizing Agents

1995
Perylenequinones in photodynamic therapy: cellular versus vascular response.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2006, Volume: 25, Issue:1-2

    Topics: Animals; Anthracenes; Apoptosis; Blood Vessels; Humans; Neoplasms; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Quinones

2006

Other Studies

11 other study(ies) available for hypocrellin a and hypericin

ArticleYear
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Roles of oxygen and photoinduced acidification in the light-dependent antiviral activity of hypocrellin A.
    Biochemistry, 1995, Dec-05, Volume: 34, Issue:48

    Topics: Anthracenes; Antiviral Agents; HIV; Hydrogen-Ion Concentration; Light; Oxygen; Perylene; Phenol; Photochemistry; Quinones

1995
Hypocrellin, from Hypocrella bambuase, is phototoxic to human immunodeficiency virus.
    Photochemistry and photobiology, 1994, Volume: 60, Issue:3

    Topics: 3T3 Cells; Animals; Anthracenes; Antiviral Agents; Cell Line; Cytomegalovirus; Darkness; HIV-1; Humans; Hypocreales; Light; Mice; Perylene; Phenol; Quinones; Radiation-Sensitizing Agents

1994
The role of oxygen in the antiviral activity of hypericin and hypocrellin.
    Photochemistry and photobiology, 1998, Volume: 68, Issue:4

    Topics: Adenosine Triphosphate; Animals; Anthracenes; Antiviral Agents; Horses; Infectious Anemia Virus, Equine; Light; Luminescent Measurements; Microbial Sensitivity Tests; Oxygen; Perylene; Phenol; Photochemistry; Quinones; Singlet Oxygen

1998
The effect of hypericin and hypocrellin-A on lipid membranes and membrane potential of 3T3 fibroblasts.
    Biochimica et biophysica acta, 1999, Apr-14, Volume: 1418, Issue:1

    Topics: 3T3 Cells; Animals; Anthracenes; Dimyristoylphosphatidylcholine; Lipid Bilayers; Membrane Fluidity; Membrane Potentials; Mice; Perylene; Phenol; Photochemistry; Photosensitizing Agents; Proteolipids; Quinones; Sodium-Potassium-Exchanging ATPase; Spectrometry, Fluorescence

1999
Photophysics of hypericin and hypocrellin A in complex with subcellular components: interactions with human serum albumin.
    Photochemistry and photobiology, 1999, Volume: 69, Issue:6

    Topics: Anthracenes; Energy Transfer; Fluorescence Polarization; Humans; In Vitro Techniques; Macromolecular Substances; Perylene; Phenol; Photochemistry; Quinones; Serum Albumin, Bovine

1999
Hypocrellin and hypericin-induced phototoxicity of HL-60 cells: apoptosis or necrosis?
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2000, Volume: 7, Issue:6

    Topics: Anthracenes; Antineoplastic Agents; Apoptosis; Drugs, Chinese Herbal; HL-60 Cells; Humans; Necrosis; Perylene; Phenol; Photosensitizing Agents; Quinones

2000
Hypericin and hypocrellin induced apoptosis in human mucosal carcinoma cells.
    Journal of photochemistry and photobiology. B, Biology, 2001, Dec-01, Volume: 65, Issue:1

    Topics: Anthracenes; Antineoplastic Agents; Apoptosis; Caspase 3; Caspases; Cell Line; Cell Membrane; Cell Size; Cell Survival; DNA, Neoplasm; Enzyme Activation; Humans; Mucous Membrane; Nasopharyngeal Neoplasms; Perylene; Phenol; Phosphatidylserines; Photosensitizing Agents; Poly(ADP-ribose) Polymerases; Quinones; Tumor Cells, Cultured

2001
Hypocrellins and Hypericin induced apoptosis in human tumor cells: a possible role of hydrogen peroxide.
    International journal of molecular medicine, 2002, Volume: 9, Issue:5

    Topics: Anthracenes; Apoptosis; Caspase 3; Caspases; Cytochrome c Group; DNA Fragmentation; Enzyme Activation; Flow Cytometry; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Membrane Potentials; Microscopy, Electron; Mitochondria; Perylene; Phenol; Photosensitizing Agents; Poly(ADP-ribose) Polymerases; Quinones; Reactive Oxygen Species; Tumor Cells, Cultured

2002
Potentiation of hypericin and hypocrellin-induced phototoxicity by omeprazole.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 1999, Volume: 6, Issue:5

    Topics: Anthracenes; Antineoplastic Agents; Antiviral Agents; Cell Survival; Drug Synergism; HL-60 Cells; Humans; Omeprazole; Perylene; Phenol; Photosensitizing Agents; Quinones

1999
Anion of hypericin is crucial to understanding the photosensitive features of the pigment.
    Bioorganic & medicinal chemistry letters, 2006, Mar-01, Volume: 16, Issue:5

    Topics: Anions; Anthracenes; Electrons; Molecular Structure; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Pigments, Biological; Quinones; Singlet Oxygen

2006