Page last updated: 2024-08-22

hypochlorous acid and pirenzepine

hypochlorous acid has been researched along with pirenzepine in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fu, JM; Rakhit, S; Tehim, A; Uetrecht, J; Zahid, N1
Gardner, I; MacCrimmon, D; Uetrecht, JP; Zahid, N1
Chin, T; Gardner, I; Leeder, JS; Uetrecht, JP; Zahid, N1
Iverson, S; Uetrecht, JP; Zahid, N1

Other Studies

4 other study(ies) available for hypochlorous acid and pirenzepine

ArticleYear
Structural features associated with reactive metabolite formation in clozapine analogues.
    Chemico-biological interactions, 1997, May-02, Volume: 104, Issue:2-3

    Topics: Agranulocytosis; Antipsychotic Agents; Benzodiazepines; Binding Sites; Chromatography, High Pressure Liquid; Chromatography, Liquid; Clozapine; Dibenzazepines; Glutathione; Granulocytes; Humans; Hydrogen Peroxide; Hypochlorous Acid; Lymphocyte Activation; Mass Spectrometry; Neutrophils; Nitrogen; Olanzapine; Oxidation-Reduction; Peroxidase; Pirenzepine; Structure-Activity Relationship

1997
A comparison of the oxidation of clozapine and olanzapine to reactive metabolites and the toxicity of these metabolites to human leukocytes.
    Molecular pharmacology, 1998, Volume: 53, Issue:6

    Topics: Agranulocytosis; Antipsychotic Agents; Benzodiazepines; Clozapine; HL-60 Cells; Humans; Hypochlorous Acid; Neutrophils; Olanzapine; Oxidation-Reduction; Pirenzepine

1998
A comparison of the covalent binding of clozapine and olanzapine to human neutrophils in vitro and in vivo.
    Molecular pharmacology, 1998, Volume: 53, Issue:6

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; Bone Marrow; Clozapine; Female; Humans; Hypochlorous Acid; Immune Sera; Immunoblotting; Male; Neutrophils; Olanzapine; Peroxidase; Pirenzepine; Rabbits; Rats; Rats, Inbred Lew

1998
Predicting drug-induced agranulocytosis: characterizing neutrophil-generated metabolites of a model compound, DMP 406, and assessing the relevance of an in vitro apoptosis assay for identifying drugs that may cause agranulocytosis.
    Chemico-biological interactions, 2002, Nov-10, Volume: 142, Issue:1-2

    Topics: Agranulocytosis; Antipsychotic Agents; Apoptosis; Benzodiazepines; Chromatography, High Pressure Liquid; Chromatography, Liquid; Clozapine; Cyanides; Horseradish Peroxidase; Humans; Hydrogen Peroxide; Hypochlorous Acid; Mass Spectrometry; Mianserin; Neutrophils; Nuclear Medicine; Olanzapine; Pirenzepine

2002