Page last updated: 2024-08-22

hypochlorous acid and hypothiocyanite ion

hypochlorous acid has been researched along with hypothiocyanite ion in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (8.33)29.6817
2010's18 (75.00)24.3611
2020's4 (16.67)2.80

Authors

AuthorsStudies
Ashby, MT; Xulu, BA1
Barrett, TJ; Brown, BE; Davies, MJ; Hawkins, CL; Ismael, FO; Sheipouri, D1
Davies, MJ; Hawkins, CL; Lloyd, MM; van Reyk, DM1
Davies, MJ; Hawkins, CL; Pattison, DI; Stanley, NR1
Cook, NL; Davies, MJ; Hool, LC; Schöneich, C; Sharov, VS; Viola, HM1
Davies, MJ; Hawkins, CL; Pattison, DI1
Cao, Z; Cheng, G; Li, H; Thannickal, VJ; Zhang, G1
Cook, NL; Davies, MJ; Pattison, DI1
Davies, MJ; Pattison, DI; Schiesser, CH; Storkey, C; White, JM1
Brown, BE; Davies, MJ; Hadfield, KA; Hawkins, CL; Hou, L; Pattison, DI; Rye, KA1
Chandler, JD; Day, BJ; Hondal, RJ; Nichols, DP; Nick, JA1
Davies, MJ; Kwan, J; Suryo Rahmanto, A; Talib, J; Witting, PK1
Davies, MJ; Grima, MA; Hadfield, KA; Hawkins, CL; Lloyd, MM; Rayner, BS1
Hawkins, CL; Love, DT; Rayner, BS1
Brown, BE; Croft, KD; Davies, MJ; Hawkins, CL; Ismael, FO; Proudfoot, JM; van Reyk, DM1
Davies, MJ; Talib, J1
Hampton, MB; Kettle, AJ; Winterbourn, CC1
Dahl, JU; Groitl, B; Jakob, U; Schroeder, JW1
Abdo, AI; Hawkins, CL; Rayner, BS; van Reyk, DM1
Hawkins, CL; Rayner, BS; Reyes, L1
Brazhe, NA; Guo, C; Hawkins, CL; Love, DT; Nikelshparg, EI; Sosnovtseva, O1
Leichert, LI; Ulfig, A1
Davies, JC; Farrant, KV; Spiga, L; Williams, HD1
Hampton, MB; Hua, H; Kaldor, CD; Kettle, AJ; Parker, HA; Shearer, HL1

Reviews

4 review(s) available for hypochlorous acid and hypothiocyanite ion

ArticleYear
Reactions and reactivity of myeloperoxidase-derived oxidants: differential biological effects of hypochlorous and hypothiocyanous acids.
    Free radical research, 2012, Volume: 46, Issue:8

    Topics: Humans; Hydrogen Peroxide; Hypochlorous Acid; Kinetics; Oxidants; Oxidation-Reduction; Oxidative Stress; Peroxidase; Phagocytes; Sulfhydryl Compounds; Thiocyanates

2012
Comparative reactivity of myeloperoxidase-derived oxidants with mammalian cells.
    Free radical biology & medicine, 2014, Volume: 71

    Topics: Animals; Bromates; Calcium; Endothelial Cells; Epithelial Cells; Erythrocytes; Humans; Hydrogen Peroxide; Hypochlorous Acid; Inflammation; Intracellular Signaling Peptides and Proteins; Oxidants; Oxidative Stress; Peroxidase; Signal Transduction; Thiocyanates

2014
Reactive Oxygen Species and Neutrophil Function.
    Annual review of biochemistry, 2016, Jun-02, Volume: 85

    Topics: Cell Membrane; Cells, Cultured; Chloramines; Gene Expression; Humans; Hydrogen Peroxide; Hypochlorous Acid; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; Neutrophils; Oxidation-Reduction; Peroxidase; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Thiocyanates; Zymosan

2016
The effects of neutrophil-generated hypochlorous acid and other hypohalous acids on host and pathogens.
    Cellular and molecular life sciences : CMLS, 2021, Volume: 78, Issue:2

    Topics: Animals; Bacteria; Bacterial Infections; Bacterial Physiological Phenomena; Bromates; Extracellular Traps; Host-Pathogen Interactions; Humans; Hypochlorous Acid; Inflammation; Neutrophils; Phagocytosis; Thiocyanates

2021

Other Studies

20 other study(ies) available for hypochlorous acid and hypothiocyanite ion

ArticleYear
Small molecular, macromolecular, and cellular chloramines react with thiocyanate to give the human defense factor hypothiocyanite.
    Biochemistry, 2010, Mar-09, Volume: 49, Issue:9

    Topics: Anti-Infective Agents; Chloramines; Chlorine; Disinfection; Escherichia coli; Humans; Hypochlorous Acid; Macromolecular Substances; Oxidation-Reduction; Spectrophotometry, Ultraviolet; Taurine; Thiocyanates; Trinitrobenzenesulfonic Acid; Ubiquitin

2010
Role of Myeloperoxidase Oxidants in the Modulation of Cellular Lysosomal Enzyme Function: A Contributing Factor to Macrophage Dysfunction in Atherosclerosis?
    PloS one, 2016, Volume: 11, Issue:12

    Topics: Animals; Atherosclerosis; Cathepsins; Cell Line; Humans; Hypochlorous Acid; Lipase; Lipoproteins, LDL; Lysosomal Membrane Proteins; Lysosomes; Macrophages; Mice; Peroxidase; Thiocyanates

2016
Hypothiocyanous acid is a more potent inducer of apoptosis and protein thiol depletion in murine macrophage cells than hypochlorous acid or hypobromous acid.
    The Biochemical journal, 2008, Sep-01, Volume: 414, Issue:2

    Topics: Animals; Apoptosis; Bromates; Caspases; Cell Line; Cytochromes c; Glutathione; Glutathione Disulfide; Hypochlorous Acid; Macrophages; Mice; Necrosis; Oxidation-Reduction; Sulfhydryl Compounds; Thiocyanates

2008
Tryptophan residues are targets in hypothiocyanous acid-mediated protein oxidation.
    The Biochemical journal, 2008, Dec-15, Volume: 416, Issue:3

    Topics: Amino Acid Sequence; Antioxidants; Ascorbic Acid; Fluorescent Dyes; Glutathione; Humans; Hypochlorous Acid; Molecular Sequence Data; Molecular Structure; Myoglobin; Oxidation-Reduction; Peptide Fragments; Peptide Mapping; Protein Denaturation; Serum Albumin; Sulfhydryl Compounds; Thiocyanates; Tryptophan

2008
Myeloperoxidase-derived oxidants inhibit sarco/endoplasmic reticulum Ca2+-ATPase activity and perturb Ca2+ homeostasis in human coronary artery endothelial cells.
    Free radical biology & medicine, 2012, Mar-01, Volume: 52, Issue:5

    Topics: Calcium; Calcium Signaling; Cells, Cultured; Chloramines; Coronary Vessels; Endoplasmic Reticulum; Endothelial Cells; Humans; Hypochlorous Acid; Oxidants; Oxidation-Reduction; Peroxidase; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sulfhydryl Compounds; Thiocyanates

2012
Vascular peroxidase 1 catalyzes the formation of hypohalous acids: characterization of its substrate specificity and enzymatic properties.
    Free radical biology & medicine, 2012, Nov-15, Volume: 53, Issue:10

    Topics: Biocatalysis; Bromates; Heme; Humans; Hydrogen Peroxide; Hypochlorous Acid; Kinetics; Oxidation-Reduction; Peroxidase; Peroxidases; Substrate Specificity; Taurine; Thiocyanates

2012
Myeloperoxidase-derived oxidants rapidly oxidize and disrupt zinc-cysteine/histidine clusters in proteins.
    Free radical biology & medicine, 2012, Dec-01, Volume: 53, Issue:11

    Topics: Alcohol Dehydrogenase; Binding Sites; Bromates; Catalytic Domain; Coordination Complexes; Cysteine; Histidine; Hypochlorous Acid; Kinetics; Oxidants; Oxidation-Reduction; Peroxidase; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thiocyanates

2012
Preventing protein oxidation with sugars: scavenging of hypohalous acids by 5-selenopyranose and 4-selenofuranose derivatives.
    Chemical research in toxicology, 2012, Nov-19, Volume: 25, Issue:11

    Topics: Free Radical Scavengers; Hypochlorous Acid; Molecular Structure; Monosaccharides; Organoselenium Compounds; Oxidation-Reduction; Peroxidase; Thiocyanates

2012
Myeloperoxidase-derived oxidants modify apolipoprotein A-I and generate dysfunctional high-density lipoproteins: comparison of hypothiocyanous acid (HOSCN) with hypochlorous acid (HOCl).
    The Biochemical journal, 2013, Jan-15, Volume: 449, Issue:2

    Topics: Amino Acid Sequence; Apolipoprotein A-I; Biological Transport; Cell Line; Cells, Cultured; Cholesterol; E-Selectin; Endothelium, Vascular; Female; Flow Cytometry; Humans; Hypochlorous Acid; Intercellular Adhesion Molecule-1; Lipoproteins, HDL; Macrophages; Male; Molecular Sequence Data; Oxidants; Oxidation-Reduction; Peptides; Peroxidase; Thiocyanates; Vascular Cell Adhesion Molecule-1

2013
Selective metabolism of hypothiocyanous acid by mammalian thioredoxin reductase promotes lung innate immunity and antioxidant defense.
    The Journal of biological chemistry, 2013, Jun-21, Volume: 288, Issue:25

    Topics: Amino Acid Substitution; Animals; Antioxidants; Auranofin; Bacterial Proteins; Bronchioles; Cell Survival; Cells, Cultured; Cysteine; Epithelial Cells; Humans; Hypochlorous Acid; Immunity, Innate; Kinetics; Lung; Mice; Microbial Viability; Rats; Selenocysteine; Substrate Specificity; Thiocyanates; Thioredoxin-Disulfide Reductase

2013
The smoking-associated oxidant hypothiocyanous acid induces endothelial nitric oxide synthase dysfunction.
    The Biochemical journal, 2014, Jan-01, Volume: 457, Issue:1

    Topics: Animals; Cells, Cultured; Enzyme Activation; Humans; Hypochlorous Acid; Male; Nitric Oxide Synthase Type III; Oxidants; Peroxidase; Protein Multimerization; Rats; Rats, Wistar; Smoking; Thiocyanates

2014
Comparative reactivity of the myeloperoxidase-derived oxidants hypochlorous acid and hypothiocyanous acid with human coronary artery endothelial cells.
    Free radical biology & medicine, 2013, Volume: 65

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Apoptosis Inducing Factor; Atherosclerosis; Caspase 3; Caspase 7; Caspase Inhibitors; Cell Line; Cell Survival; Coronary Vessels; Cytochromes c; Endodeoxyribonucleases; Endothelial Cells; Glutathione; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating); Humans; Hydrogen Peroxide; Hypochlorous Acid; Mitochondrial Membranes; Necrosis; Oxidation-Reduction; Permeability; Peroxidase; Sulfhydryl Compounds; Thiocyanates

2013
Comparative reactivity of the myeloperoxidase-derived oxidants HOCl and HOSCN with low-density lipoprotein (LDL): Implications for foam cell formation in atherosclerosis.
    Archives of biochemistry and biophysics, 2015, May-01, Volume: 573

    Topics: Animals; Apolipoprotein B-100; Atherosclerosis; Cell Line; Cholesterol; Cholesterol Esters; Foam Cells; Humans; Hypochlorous Acid; Lipoproteins, LDL; Macrophages; Mice; Oxidants; Oxidation-Reduction; Peroxidase; Thiocyanates

2015
Exposure of aconitase to smoking-related oxidants results in iron loss and increased iron response protein-1 activity: potential mechanisms for iron accumulation in human arterial cells.
    Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2016, Volume: 21, Issue:3

    Topics: Aconitate Hydratase; Cells, Cultured; Coronary Vessels; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Hypochlorous Acid; Iron; Iron Deficiencies; Iron-Regulatory Proteins; Oxidants; Smoking; Structure-Activity Relationship; Thiocyanates

2016
Pseudomonas aeruginosa defense systems against microbicidal oxidants.
    Molecular microbiology, 2017, Volume: 106, Issue:3

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Bromates; Hypochlorous Acid; Oxidants; Pseudomonas aeruginosa; Thiocyanates

2017
Low-density lipoprotein modified by myeloperoxidase oxidants induces endothelial dysfunction.
    Redox biology, 2017, Volume: 13

    Topics: Animals; Aorta; Cells, Cultured; Endothelial Cells; Hypochlorous Acid; Lipoproteins, LDL; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Peroxidase; Rats; Rats, Sprague-Dawley; Thiocyanates; Vasodilation

2017
Characterization of the cellular effects of myeloperoxidase-derived oxidants on H9c2 cardiac myoblasts.
    Archives of biochemistry and biophysics, 2019, 04-15, Volume: 665

    Topics: Animals; Cell Line; Glutathione; Hypochlorous Acid; Myoblasts, Cardiac; Oxidants; Oxidative Stress; Peroxidase; Rats; Signal Transduction; Thiocyanates

2019
The role of the myeloperoxidase-derived oxidant hypothiocyanous acid (HOSCN) in the induction of mitochondrial dysfunction in macrophages.
    Redox biology, 2020, Volume: 36

    Topics: Cell Line; Hypochlorous Acid; Macrophages; Mitochondria; Oxidants; Oxidation-Reduction; Peroxidase; Thiocyanates

2020
Response of Pseudomonas aeruginosa to the Innate Immune System-Derived Oxidants Hypochlorous Acid and Hypothiocyanous Acid.
    Journal of bacteriology, 2020, 12-18, Volume: 203, Issue:2

    Topics: Bacterial Proteins; DNA Transposable Elements; DNA-Binding Proteins; Down-Regulation; Drug Resistance, Microbial; Genes, Regulator; Hypochlorous Acid; Mutation; Oxidants; Plasmids; Polymerase Chain Reaction; Pseudomonas aeruginosa; RNA, Bacterial; RNA, Transfer; Thiocyanates; Trans-Activators; Transcription Factors; Up-Regulation

2020
Resistance of Streptococcus pneumoniae to Hypothiocyanous Acid Generated by Host Peroxidases.
    Infection and immunity, 2022, 03-17, Volume: 90, Issue:3

    Topics: Humans; Hydrogen Peroxide; Hypochlorous Acid; Lactoperoxidase; Peroxidase; Peroxidases; Proteins; Streptococcus pneumoniae; Thiocyanates

2022