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hypochlorous acid and acetylcysteine

hypochlorous acid has been researched along with acetylcysteine in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.88)18.7374
1990's6 (35.29)18.2507
2000's7 (41.18)29.6817
2010's3 (17.65)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bast, A; Haenen, GR1
Aruoma, OI; Butler, J; Halliwell, B; Hoey, BM1
Brunet, C; Cazin, JC; Cazin, M; Dine, T; Gressier, B; Lebegue, N; Luyckx, M1
Abernathy, F; Pacht, ER1
Bartling, A; Gillissen, A; Jaworska, M; Rasche, K; Schärling, B; Schultze-Werninghaus, G1
Maes, P; Nève, J; Vanderbist, F1
Lai, WG; Uetrecht, JP; Zahid, N1
Gardner, I; Lai, WG; Uetrecht, JP; Zahid, N1
Bast, A; den Hartog, GJ; Haenen, GR; van der Vijgh, WJ; Vegt, E1
Hosoe, H; Kaise, T; Ohmori, K1
Allegra, L; Bovio, C; Braga, PC; Dal Sasso, M; Fonti, E; Massoni, C1
Carr, AC; Frei, B; Zhu, BZ1
Constable, PD; Eurell, JA; Freeman, DE; Rötting, AK; Wallig, M1
Durante, W; Johnson, FK; Johnson, RA; Liu, XM; Peyton, KJ; Wang, H; Wei, Y1
Chordia, MD; Huang, T; Li, F; Linden, J; Macdonald, TL; Yang, M1
Arab, HH; Maghrabi, IA; Omar, HA; Salama, SA; Snapka, RM1
Guo, X; Han, L; Jia, Y; Li, W; Peng, Y; Zhang, Z; Zhao, Y; Zheng, J1

Other Studies

17 other study(ies) available for hypochlorous acid and acetylcysteine

ArticleYear
Scavenging of hypochlorous acid by lipoic acid.
    Biochemical pharmacology, 1991, Nov-06, Volume: 42, Issue:11

    Topics: Acetylcysteine; alpha 1-Antitrypsin; Enzyme Activation; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Hypochlorous Acid; Kinetics; Oxidation-Reduction; Pancreatic Elastase; Thioctic Acid

1991
The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid.
    Free radical biology & medicine, 1989, Volume: 6, Issue:6

    Topics: Acetylcysteine; alpha 1-Antitrypsin; Antioxidants; Blood Proteins; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Hypochlorous Acid; Kinetics; Pancreatic Elastase; Protease Inhibitors; Superoxides

1989
Scavenging of reactive oxygen species by letosteine, a molecule with two blocked-SH groups. Comparison with free-SH drugs.
    Pharmacy world & science : PWS, 1995, May-26, Volume: 17, Issue:3

    Topics: Acetylcysteine; Antioxidants; Dose-Response Relationship, Drug; Drug Interactions; Expectorants; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrolysis; Hydroxyl Radical; Hypochlorous Acid; Mesna; Reactive Oxygen Species; Respiratory Burst; Superoxides; Thiazoles; Thiazolidines

1995
Prevention of intracellular adenosine triphosphate depletion after sublethal oxidant injury to rat type II alveolar epithelial cells with exogenous glutathione and N-acetylcysteine.
    The American journal of the medical sciences, 1995, Volume: 310, Issue:4

    Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Glutathione; Hydrogen Peroxide; Hypochlorous Acid; Male; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley

1995
Oxidant scavenger function of ambroxol in vitro: a comparison with N-acetylcysteine.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1997, Volume: 196, Issue:6

    Topics: Acetylcysteine; Ambroxol; Antioxidants; Expectorants; Free Radical Scavengers; Glutathione; Hydrogen Peroxide; Hydroxides; Hypochlorous Acid; In Vitro Techniques; Superoxides

1997
In vitro comparative assessment of the antioxidant activity of nacystelyn against three reactive oxygen species.
    Arzneimittel-Forschung, 1996, Volume: 46, Issue:8

    Topics: Acetylcysteine; Antioxidants; Captopril; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Hypochlorous Acid; Kinetics; Lysine; Reactive Oxygen Species

1996
Metabolism of trimethoprim to a reactive iminoquinone methide by activated human neutrophils and hepatic microsomes.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:1

    Topics: Acetylcysteine; Animals; Drug Interactions; Free Radical Scavengers; Humans; Hypochlorous Acid; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Microsomes, Liver; Neutrophils; Oxidation-Reduction; Peroxidase; Quinones; Rats; Rats, Sprague-Dawley; Trimethoprim; Tritium

1999
Bioactivation and covalent binding of hydroxyfluperlapine in human neutrophils: implications for fluperlapine-induced agranulocytosis.
    Drug metabolism and disposition: the biological fate of chemicals, 2000, Volume: 28, Issue:3

    Topics: Acetylcysteine; Agranulocytosis; Binding, Competitive; Clozapine; Dibenzazepines; Glutathione; Hemocyanins; Humans; Hypochlorous Acid; Immune Sera; Immunoblotting; Neutrophil Activation; Neutrophils; Oxidation-Reduction; Peroxidase; Protein Binding

2000
Hypochlorous acid is a potent inhibitor of acetylcholinesterase.
    Toxicology and applied pharmacology, 2002, Jun-15, Volume: 181, Issue:3

    Topics: Acetylcholinesterase; Acetylcysteine; Animals; Atropine; Cholinergic Fibers; Cholinesterase Inhibitors; Electric Stimulation; Expectorants; Guinea Pigs; Hypochlorous Acid; In Vitro Techniques; Kinetics; Male; Muscarinic Antagonists; Muscle Tonus; Muscle, Smooth; Trachea

2002
Effects on the reactive oxygen species of erdosteine and its metabolite in vitro.
    Arzneimittel-Forschung, 2002, Volume: 52, Issue:6

    Topics: Acetylcysteine; Antioxidants; Glutathione; Hydrogen Peroxide; Hypochlorous Acid; Kinetics; Reactive Oxygen Species; Superoxides; Thioglycolates; Thiophenes

2002
Human neutrophil oxidative bursts and their in vitro modulation by different N-acetylcysteine concentrations.
    Arzneimittel-Forschung, 2002, Volume: 52, Issue:9

    Topics: Acetylcysteine; Adult; Candida albicans; Cell-Free System; Dose-Response Relationship, Drug; Escherichia coli; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hypochlorous Acid; Immunity, Cellular; Luminescent Measurements; Luminol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidants; Phagocytosis; Respiratory Burst; Staphylococcus aureus; Xanthine Oxidase

2002
Pyrrolidine dithiocarbamate is a potent antioxidant against hypochlorous acid-induced protein damage.
    FEBS letters, 2002, Dec-04, Volume: 532, Issue:1-2

    Topics: Acetylcysteine; Aldehydes; alpha 1-Antitrypsin; Antioxidants; Chlorine; Cyclohexanones; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ferrocyanides; Glutathione; Hypochlorous Acid; Lipoproteins, LDL; Oxidants; Oxidation-Reduction; Oxidative Stress; Pyrrolidines; Serum Albumin; Thiocarbamates

2002
Effects of acetylcysteine and migration of resident eosinophils in an in vitro model of mucosal injury and restitution in equine right dorsal colon.
    American journal of veterinary research, 2003, Volume: 64, Issue:10

    Topics: Acetylcysteine; Animals; Chemotaxis, Leukocyte; Colon; Eosinophils; Horses; Hypochlorous Acid; In Vitro Techniques; Intestinal Mucosa; Models, Biological; Muscle, Smooth; Wound Healing

2003
Hypochlorous acid-induced heme oxygenase-1 gene expression promotes human endothelial cell survival.
    American journal of physiology. Cell physiology, 2009, Volume: 297, Issue:4

    Topics: Acetylcysteine; Antioxidants; Carbon Monoxide; Cell Survival; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Enzyme Activation; Gene Expression Regulation; Heme Oxygenase-1; Humans; Hypochlorous Acid; Metalloporphyrins; NF-E2-Related Factor 2; Peroxidase; Protoporphyrins; RNA, Messenger

2009
Neutrophil- and myeloperoxidase-mediated metabolism of reduced nimesulide: evidence for bioactivation.
    Chemical research in toxicology, 2010, Nov-15, Volume: 23, Issue:11

    Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, Liquid; Humans; Hydrogen Peroxide; Hypochlorous Acid; Microsomes, Liver; Neutrophils; Oxidation-Reduction; Peroxidase; Sulfonamides; Tandem Mass Spectrometry

2010
Nicotine mediates hypochlorous acid-induced nuclear protein damage in mammalian cells.
    Inflammation, 2014, Volume: 37, Issue:3

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Cell Line; Cell Proliferation; Chromans; Glutathione; Humans; Hypochlorous Acid; Inflammation; Kidney; Lung; Neutrophils; Nicotine; Oxidation-Reduction; Proliferating Cell Nuclear Antigen

2014
Metabolic Activation of Tofacitinib Mediated by Myeloperoxidase
    Chemical research in toxicology, 2019, 12-16, Volume: 32, Issue:12

    Topics: Acetylcysteine; Activation, Metabolic; Animals; Antirheumatic Agents; Hypochlorous Acid; Leukocytes; Leukopenia; Peroxidase; Piperidines; Pyrimidines; Pyrroles; Rats, Sprague-Dawley

2019