hypochlorous acid has been researched along with 3-chloro-L-tyrosine in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (22.73) | 18.2507 |
| 2000's | 13 (59.09) | 29.6817 |
| 2010's | 4 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kettle, AJ | 2 |
| Hazen, SL; Heinecke, JW | 1 |
| Crowley, JR; Hazen, SL; Heinecke, JW; Mueller, DM | 1 |
| Baker, C; Evans, TW; Gutteridge, JM; Lamb, NJ; Quinlan, GJ | 1 |
| Davies, M; Dean, R; Fu, S; Wang, H | 1 |
| Chapman, AL; Kettle, AJ; Senthilmohan, R; Winterbourn, CC | 1 |
| Anderson, MM; Brennan, ML; Crowley, JR; Hazen, SL; Heinecke, JW; Jacob, JS; Lim, LL; Lusis, AJ; Mehta, AC; Qu, XD; Shi, W; Shih, DM; Wang, X | 1 |
| Pizzo, SV; Wu, SM | 1 |
| Belaaouaj, A; Brennan, ML; Byun, J; Gaut, JP; Heinecke, JW; Henderson, JP; Hotchkiss, RS; Lusis, AJ; Richter, GM; Tran, HD; Yeh, GC | 1 |
| Crowley, JR; Heinecke, JW; Rosen, H | 1 |
| Fisher, MT; Khor, HK; Schöneich, C | 1 |
| Anantharamaiah, GM; Bergt, C; Brunzell, J; Byun, J; Chait, A; Fu, X; Geary, RL; Heinecke, JW; McDonald, TO; O'Brien, K; Oram, JF; Pennathur, S; Singh, P | 1 |
| Choi, DK; Heinecke, JW; Jackson-Lewis, V; Pennathur, S; Perier, C; Przedborski, S; Teismann, P; Tieu, K; Vila, M; Vonsattel, JP; Wu, DC | 1 |
| Spencer, JP; Whiteman, M | 1 |
| Kang, JI; Neidigh, JW | 1 |
| Gugliucci, A | 1 |
| Haroune, N; Mouls, L; Pitt, AR; Silajdzic, E; Spickett, CM | 1 |
| De Groote, D; Paquet, P; Piérard, GE | 1 |
| Curtis, MP; Hicks, AJ; Neidigh, JW | 1 |
| Heinecke, JW; Pennathur, S; Shao, B | 1 |
| Cheng, D; Maghzal, GJ; Stocker, R; Talib, J | 1 |
22 other study(ies) available for hypochlorous acid and 3-chloro-L-tyrosine
| Article | Year |
|---|---|
Neutrophils convert tyrosyl residues in albumin to chlorotyrosine.
Topics: Amino Acid Sequence; Humans; Hypochlorous Acid; In Vitro Techniques; Inflammation; Molecular Sequence Data; Neutrophils; Oligopeptides; Peroxidase; Serum Albumin; Tyrosine | 1996 |
3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima.
Topics: Aorta; Apolipoproteins B; Arteriosclerosis; Biomarkers; Chlorine; Humans; Hypochlorous Acid; Lipoproteins; Lipoproteins, LDL; Oxidation-Reduction; Peroxidase; Phagocytes; Tyrosine | 1997 |
Mass spectrometric quantification of 3-chlorotyrosine in human tissues with attomole sensitivity: a sensitive and specific marker for myeloperoxidase-catalyzed chlorination at sites of inflammation.
Topics: Analysis of Variance; Aorta; Arteriosclerosis; Biomarkers; Calibration; Carbon; Carbon Isotopes; Catalysis; Chlorine; Female; Gas Chromatography-Mass Spectrometry; Humans; Hypochlorous Acid; Inflammation; Lipoproteins, LDL; Male; Peroxidase; Sensitivity and Specificity; Tyrosine | 1997 |
Detection of 3-chlorotyrosine in proteins exposed to neutrophil oxidants.
Topics: Blood Proteins; Chlorides; Chromatography, High Pressure Liquid; Electrochemistry; Fluorescence; Humans; Hydrogen Peroxide; Hypochlorous Acid; Neutrophils; Oxidants; Peroxidase; Tyrosine | 1999 |
Oxidative damage to proteins of bronchoalveolar lavage fluid in patients with acute respiratory distress syndrome: evidence for neutrophil-mediated hydroxylation, nitration, and chlorination.
Topics: Adolescent; Adult; Aged; Biomarkers; Bronchoalveolar Lavage Fluid; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Humans; Hydroxyl Radical; Hydroxylation; Hypochlorous Acid; Linear Models; Male; Middle Aged; Neutrophil Activation; Neutrophils; Nitrates; Oxidants; Oxidative Stress; Proteins; Respiration, Artificial; Respiratory Distress Syndrome; Statistics, Nonparametric; Tyrosine | 1999 |
Reactions of hypochlorous acid with tyrosine and peptidyl-tyrosyl residues give dichlorinated and aldehydic products in addition to 3-chlorotyrosine.
Topics: Animals; Humans; Hypochlorous Acid; Lipoproteins, LDL; Mice; Monophenol Monooxygenase; Oxidation-Reduction; Serum Albumin, Bovine; Tyrosine | 2000 |
Comparison of mono- and dichlorinated tyrosines with carbonyls for detection of hypochlorous acid modified proteins.
Topics: Animals; Antibodies; Antibody Specificity; Bromates; Carbonic Acid; Cattle; Chlorine; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Epitopes; Hypochlorous Acid; Inflammation; Mass Spectrometry; Oxidants; Oxidative Stress; Serum Albumin; Tyrosine | 2000 |
Increased atherosclerosis in myeloperoxidase-deficient mice.
Topics: Animals; Arteriosclerosis; Candida albicans; Humans; Hypochlorous Acid; Mice; Mice, Inbred C57BL; Neutrophils; Oxidation-Reduction; Peroxidase; Phagocytes; Tyrosine | 2001 |
alpha(2)-Macroglobulin from rheumatoid arthritis synovial fluid: functional analysis defines a role for oxidation in inflammation.
Topics: alpha-Macroglobulins; Arthritis, Rheumatoid; Humans; Hypochlorous Acid; Mass Spectrometry; Osteoarthritis; Oxidation-Reduction; Peptide Hydrolases; Synovial Fluid; Tyrosine | 2001 |
Neutrophils employ the myeloperoxidase system to generate antimicrobial brominating and chlorinating oxidants during sepsis.
Topics: Animals; Bromine; Chlorine; Disease Models, Animal; HL-60 Cells; Humans; Hypochlorous Acid; Ions; Klebsiella Infections; Klebsiella pneumoniae; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Oxidants; Peroxidase; Sepsis; Tyrosine | 2001 |
Human neutrophils use the myeloperoxidase-hydrogen peroxide-chloride system to chlorinate but not nitrate bacterial proteins during phagocytosis.
Topics: Bacterial Proteins; Chlorides; Humans; Hydrogen Peroxide; Hypochlorous Acid; Neutrophils; Nitrites; Peroxidase; Phagocytosis; Tyrosine | 2002 |
Potential role of methionine sulfoxide in the inactivation of the chaperone GroEL by hypochlorous acid (HOCl) and peroxynitrite (ONOO-).
Topics: Amino Acid Sequence; Arteriosclerosis; Chaperonin 60; Chromatography; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Humans; Hydrolysis; Hypochlorous Acid; Mass Spectrometry; Methionine; Methionine Sulfoxide Reductases; Molecular Chaperones; Molecular Sequence Data; Oxidants; Oxidoreductases; Oxygen; Peptides; Peroxynitrous Acid; Phagocytes; Protein Binding; Time Factors; Trypsin; Tyrosine | 2004 |
The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport.
Topics: Amino Acid Sequence; Apolipoprotein A-I; Arteries; Arteriosclerosis; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Cholesterol, HDL; Chromatography, Liquid; Humans; Hypochlorous Acid; Mass Spectrometry; Molecular Sequence Data; Peroxidase; Tyrosine | 2004 |
Ablation of the inflammatory enzyme myeloperoxidase mitigates features of Parkinson's disease in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amyotrophic Lateral Sclerosis; Animals; Brain; Corpus Striatum; Dopamine; Drug Evaluation, Preclinical; Enzyme Induction; Humans; Huntington Disease; Hypochlorous Acid; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Neurons; Oxidative Stress; Parkinson Disease; Parkinsonian Disorders; Peroxidase; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tyrosine | 2005 |
Loss of 3-chlorotyrosine by inflammatory oxidants: implications for the use of 3-chlorotyrosine as a bio-marker in vivo.
Topics: Animals; Biomarkers; HL-60 Cells; Humans; Hypochlorous Acid; Inflammation; Macrophage Activation; Macrophages; Mice; Neutrophils; Nitrites; Oxidants; Peroxidase; Peroxynitrous Acid; Reactive Oxygen Species; Tyrosine | 2008 |
Hypochlorous acid damages histone proteins forming 3-chlorotyrosine and 3,5-dichlorotyrosine.
Topics: Amino Acid Sequence; Chlorine; Histones; Hypochlorous Acid; Mass Spectrometry; Molecular Sequence Data; Tyrosine | 2008 |
Hypochlorous acid is a potent inactivator of human plasminogen at concentrations secreted by activated granulocytes.
Topics: Aryldialkylphosphatase; Cysteine; Granulocytes; Humans; Hypochlorous Acid; Lipoproteins, HDL; Plasminogen; Streptokinase; Tyrosine | 2008 |
Development of novel mass spectrometric methods for identifying HOCl-induced modifications to proteins.
Topics: 5-Hydroxytryptophan; Amino Acid Sequence; Animals; Hypochlorous Acid; Mass Spectrometry; Molecular Sequence Data; Muramidase; Oxidation-Reduction; Peptides; Protein Processing, Post-Translational; Proteins; Sequence Analysis, Protein; Tyrosine | 2009 |
Functionally active macrophage-derived myeloperoxidase in the skin of drug-induced toxic epidermal necrolysis.
Topics: Adolescent; Adult; Aged; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Blister; Female; Humans; Hypochlorous Acid; Keratinocytes; Lewis X Antigen; Macrophages; Male; Middle Aged; Peroxidase; Stevens-Johnson Syndrome; Tyrosine | 2010 |
Kinetics of 3-chlorotyrosine formation and loss due to hypochlorous acid and chloramines.
Topics: Biomarkers; Chloramines; Chlorides; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Hypochlorous Acid; Kinetics; Spectrophotometry, Ultraviolet; Tyrosine | 2011 |
Myeloperoxidase targets apolipoprotein A-I, the major high density lipoprotein protein, for site-specific oxidation in human atherosclerotic lesions.
Topics: Apolipoprotein A-I; Atherosclerosis; Halogenation; Humans; Hypochlorous Acid; Lipoproteins, HDL; Nitrogen; Oxidation-Reduction; Oxidative Stress; Peroxidase; Protein Processing, Post-Translational; Tyrosine | 2012 |
Detailed protocol to assess in vivo and ex vivo myeloperoxidase activity in mouse models of vascular inflammation and disease using hydroethidine.
Topics: Animals; Biomarkers; Chromatography, Liquid; Disease Models, Animal; Halogenation; Humans; Hydrogen Peroxide; Hypochlorous Acid; Inflammation; Mice; Oxidation-Reduction; Peroxidase; Phenanthridines; Tandem Mass Spectrometry; Tyrosine; Vascular Diseases | 2016 |