hyperoside and taxifolin

hyperoside has been researched along with taxifolin* in 2 studies

Other Studies

2 other study(ies) available for hyperoside and taxifolin

ArticleYear
Flavonoids from Agrimonia pilosa Ledeb: Free Radical Scavenging and DNA Oxidative Damage Protection Activities and Analysis of Bioactivity-Structure Relationship Based on Molecular and Electronic Structures.
    Molecules (Basel, Switzerland), 2017, Feb-26, Volume: 22, Issue:3

    To clarify the substantial basis of the excellent antioxidant capacity of

    Topics: Agrimonia; Catechin; DNA Damage; Flavonoids; Molecular Structure; Oxidative Stress; Plant Extracts; Quercetin; Rutin; Structure-Activity Relationship

2017
Adenosine/guanosine preferring nucleoside ribohydrolase is a distinct, druggable antitrichomonal target.
    Bioorganic & medicinal chemistry letters, 2015, Nov-15, Volume: 25, Issue:22

    Nucleoside salvage pathway enzymes used by Trichomonas vaginalis are distinct from the pathway involved in activation of existing 5-nitroimidazole drugs. They thus represent excellent targets for developing novel, mechanism-based antitrichomonal agents. The purine-specific adenosine/guanosine preferring ribohydrolase (AGNH) was screened against the NIH Clinical Collection to assess its druggability. Eight compounds, including five flavonoids, were identified with IC50 values ⩽10 μM and confirmed in counter screens run in the presence of detergent. The inhibitors are structurally distinct from inhibitors of the pyrimidine-specific uridine ribohydrolase (UNH) thus indicating that AGNH is a distinct, druggable target from UNH.

    Topics: Adenosine; Antitrichomonal Agents; Flavonoids; High-Throughput Screening Assays; N-Glycosyl Hydrolases; Quercetin; Small Molecule Libraries; Stereoisomerism; Trichomonas vaginalis

2015