hyperoside has been researched along with cobaltous-chloride* in 1 studies
1 other study(ies) available for hyperoside and cobaltous-chloride
Article | Year |
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[Protective effects and mechanism of hyperin on CoCl2-induced PC12 cells].
To investigate the neuroprotective effects and mechanism of hyperin on CoCl2-induced hypoxic/ischemic PC12 cells.. CoCl2 was used to treat rat pheochromocytoma cell line (PC12) to investigate the protective effects of different concentrations of hyperin.. Hyperin could significantly inhibit CoCl2-induced cytotoxicity and apoptosis on PC12 cells in a dose-dependent manner, by inhibiting reactive oxygen species (ROS) production, increasing mitochondrial membrane potential (MMP), and inactivating caspase-3 and poly ADP-ribose polymerase (PARP).. Hyperin could inhibit CoCl2-induced cytotoxicity and apoptosis on PC12 cells, show neuroprotective effects on hypoxic/ischemic neural injuries. Topics: Animals; Apoptosis; Cell Survival; Cells; Cobalt; Hypericum; PC12 Cells; Plant Extracts; Protective Agents; Quercetin; Rats | 2011 |