hypericin has been researched along with quercetin in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.50) | 18.7374 |
| 1990's | 6 (15.00) | 18.2507 |
| 2000's | 17 (42.50) | 29.6817 |
| 2010's | 15 (37.50) | 24.3611 |
| 2020's | 1 (2.50) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Butterweck, V; Nahrstedt, A | 1 |
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Oliveri, V | 1 |
| Jobert, M; Schulz, H | 1 |
| Brockmöller, J; Kerb, R; Ploch, M; Roots, I; Staffeldt, B | 1 |
| Thiede, HM; Walper, A | 1 |
| Bladt, S; Wagner, H | 1 |
| Dimpfel, W; Sauer, S; Schellenberg, R | 1 |
| Cott, JM; Fugh-Berman, A | 1 |
| Obach, RS | 1 |
| Chatterjee, S; Nöldner, M | 1 |
| Coutts, RT; Gu, LD; Ling, L; Pang, PK; Shan, JJ; Sloley, BD; Urichuk, LJ | 1 |
| Mirossay, A; Mirossay, L; Mojzis, J; Onderková, H; Sarisský, M | 1 |
| Butterweck, V; Liefländer-Wulf, U; Nahrstedt, A; Winterhoff, H | 1 |
| HAGEDORN, P; NEU, R | 1 |
| Butterweck, V; Simbrey, K; Winterhoff, H | 1 |
| Borrelli, F; Capasso, F; Capasso, R; Izzo, AA; Mascolo, N | 1 |
| Bagdonaite, E; Kazlauskas, S | 1 |
| Agrimonti, C; Andreotti, E; Bianchi, A; Conforti, F; Menichini, F; Poli, F; Sacchetti, G; Statti, GA; Tundis, R | 1 |
| Bässler, D; Schulz, HU; Schürer, M; Weiser, D | 2 |
| Liu, CS; Wang, DM; Yang, DP | 1 |
| Cao, J; Chan, E; Chen, X; Duan, W; Hu, ZP; Huang, M; Wen, JY; Yang, XX; Yu, XQ; Zhou, SF | 1 |
| Contartese, G; Couladis, M; Galati, EM; Lanuzza, F; Miceli, N; Sdrafkakis, V; Taviano, MF; Tzakou, O | 1 |
| Shang, LX; Shao, CL; Wu, YX; Zhang, L; Zhang, QH | 1 |
| Cirak, C; Ivanauskas, L; Janulis, V; Radusiene, J | 2 |
| Bartolini, A; Bergonzi, MC; Bilia, AR; Galeotti, N; Ghelardini, C; Vivoli, E | 1 |
| Gilani, AH; Khan, AU | 1 |
| Kisselev, P; Roots, I; Schunck, WH; Schwarz, D | 1 |
| Hovhannisyan, AA; Martirosyan, AS; Tiratsuyan, SG; Vardapetyan, HR | 1 |
| Wang, Q; Xu, FF | 1 |
| Arakawa, NS; Cardoso, RD; Casagrande, R; Fattori, V; Hohmann, MS; Lopes, NP; Tomaz, JC; Verri, WA | 1 |
| Abdel-Aziz, H; Brügger, D; Butterweck, V; Verjee, S | 1 |
| Török, T; Varga, E | 1 |
| Kontaxis, NI; Lamari, FN; Margianni, E; Petrou, C; Zeliou, K | 1 |
| Dresler, S; Kováčik, J; Sowa, I; Strzemski, M; Wójciak-Kosior, M | 1 |
| Boonen, G; Bussmann, H; Drewe, J; Franken, S; Häberlein, H; Keksel, N; Unger, M | 1 |
| Saçıcı, E; Yesilada, E | 1 |
2 review(s) available for hypericin and quercetin
| Article | Year |
|---|---|
Lessons learned from herbal medicinal products: the example of St. John's Wort (perpendicular).
Topics: Anthracenes; Antidepressive Agents; Bridged Bicyclo Compounds; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Hypericum; Molecular Structure; Perylene; Phloroglucinol; Plant Preparations; Plants, Medicinal; Terpenes | 2010 |
Toward the discovery and development of effective modulators of α-synuclein amyloid aggregation.
Topics: alpha-Synuclein; Amyloidogenic Proteins; Drug Discovery; Humans; Protein Aggregation, Pathological; Structure-Activity Relationship | 2019 |
5 trial(s) available for hypericin and quercetin
| Article | Year |
|---|---|
Effects of hypericum extract on the sleep EEG in older volunteers.
Topics: Anthracenes; Antidepressive Agents; Cross-Over Studies; Double-Blind Method; Electroencephalography; Female; Humans; Hypericum; Middle Aged; Perylene; Plant Extracts; Plants, Medicinal; Quercetin; Sleep; Xanthenes | 1994 |
Pharmacokinetics of hypericin and pseudohypericin after oral intake of the hypericum perforatum extract LI 160 in healthy volunteers.
Topics: Administration, Oral; Adult; Anthracenes; Antidepressive Agents; Chromatography, High Pressure Liquid; Double-Blind Method; Humans; Hypericum; Male; Perylene; Plant Extracts; Plants, Medicinal; Quercetin; Reference Values; Regression Analysis; Xanthenes | 1994 |
Pharmacodynamic effects of two different hypericum extracts in healthy volunteers measured by quantitative EEG.
Topics: Adult; Anthracenes; Bridged Bicyclo Compounds; Cerebral Cortex; Electroencephalography; Female; Humans; Hypericum; Male; Perylene; Phloroglucinol; Plant Extracts; Plants, Medicinal; Quercetin; Terpenes; Xanthenes | 1998 |
Investigation of the bioavailability of hypericin, pseudohypericin, hyperforin and the flavonoids quercetin and isorhamnetin following single and multiple oral dosing of a hypericum extract containing tablet.
Topics: Adolescent; Adult; Anthracenes; Antidepressive Agents; Area Under Curve; Biological Availability; Bridged Bicyclo Compounds; Flavonols; Humans; Hypericum; Male; Middle Aged; Perylene; Phloroglucinol; Plant Extracts; Quercetin; Tablets; Terpenes | 2005 |
Investigation of pharmacokinetic data of hypericin, pseudohypericin, hyperforin and the flavonoids quercetin and isorhamnetin revealed from single and multiple oral dose studies with a hypericum extract containing tablet in healthy male volunteers.
Topics: Adolescent; Adult; Anthracenes; Bridged Bicyclo Compounds; Flavonols; Humans; Hypericum; Male; Middle Aged; Perylene; Phloroglucinol; Plant Extracts; Quercetin; Tablets; Terpenes | 2005 |
33 other study(ies) available for hypericin and quercetin
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
Inhibition of MAO and COMT by hypericum extracts and hypericin.
Topics: Animals; Anthracenes; Antidepressive Agents; Catechol O-Methyltransferase Inhibitors; Hypericum; In Vitro Techniques; Monoamine Oxidase Inhibitors; Perylene; Plant Extracts; Plants, Medicinal; Quercetin; Swine; Xanthenes | 1994 |
Pharmaceutical quality of hypericum extracts.
Topics: Anthracenes; Antidepressive Agents; Hypericum; Molecular Structure; Perylene; Plant Extracts; Plants, Medicinal; Quercetin; Xanthenes | 1994 |
Is St. John's wort (Hypericum perforatum) an effective antidepressant?
Topics: Animals; Anthracenes; Antidepressive Agents; Depressive Disorder; Humans; Hypericum; Nonprescription Drugs; Perylene; Phytotherapy; Plant Extracts; Plants, Medicinal; Protein Kinase C; Quercetin; Rats; Xanthenes | 1998 |
Inhibition of human cytochrome P450 enzymes by constituents of St. John's Wort, an herbal preparation used in the treatment of depression.
Topics: Anthracenes; Antidepressive Agents; Bridged Bicyclo Compounds; Chlorogenic Acid; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Humans; Hypericum; Perylene; Phloroglucinol; Plant Extracts; Plants, Medicinal; Quercetin; Terpenes | 2000 |
Effects of two different extracts of St. John's wort and some of their constituents on cytochrome P450 activities in rat liver microsomes.
Topics: Animals; Anthracenes; Antidepressive Agents; Bridged Bicyclo Compounds; Cytochrome P-450 Enzyme System; Ethanol; Excitatory Amino Acid Antagonists; Female; Hypericum; Liver; Male; Methanol; Microsomes; Perylene; Phenobarbital; Phloroglucinol; Plant Extracts; Quercetin; Rats; Rats, Sprague-Dawley; Sex Factors; Solvents; Terpenes | 2001 |
Chemical and pharmacological evaluation of Hypericum perforatum extracts.
Topics: Animals; Anthracenes; Antioxidants; Bridged Bicyclo Compounds; Free Radical Scavengers; Hippocampus; Hypericum; Male; Perylene; Phloroglucinol; Quercetin; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Terpenes | 2000 |
The effect of quercetin on light-induced cytotoxicity of hypericin.
Topics: Anthracenes; Cell Survival; Drug Interactions; HL-60 Cells; Humans; Light; Perylene; Photochemistry; Quercetin; Radiation-Sensitizing Agents; Reactive Oxygen Species | 2001 |
Plasma levels of hypericin in presence of procyanidin B2 and hyperoside: a pharmacokinetic study in rats.
Topics: Administration, Oral; Animals; Anthracenes; Antidepressive Agents; Biflavonoids; Biological Availability; Catechin; Chromatography, High Pressure Liquid; Drug Synergism; Male; Perylene; Phytotherapy; Plant Extracts; Proanthocyanidins; Quercetin; Rats; Rats, Sprague-Dawley; Solubility | 2003 |
[Analytic studies on flavones. IV. Determination of hypericin and hyperoside in alcoholic extracts of plants].
Topics: Anthracenes; Flavones; Perylene; Plants; Quercetin | 1954 |
Extracts of St. John's wort and various constituents affect beta-adrenergic binding in rat frontal cortex.
Topics: Animals; Anthracenes; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bridged Bicyclo Compounds; Cell Membrane; Fluoxetine; Frontal Lobe; Hypericum; Imipramine; Male; Perylene; Phloroglucinol; Plant Extracts; Quercetin; Radioligand Assay; Rats; Receptors, Adrenergic, beta; Terpenes | 2004 |
Inhibitory effect of the antidepressant St. John's wort (hypericum perforatum) on rat bladder contractility in vitro.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Anthracenes; Antidepressive Agents; Atropine; Bridged Bicyclo Compounds; Capsaicin; Depression; Electric Stimulation; Female; Haloperidol; Hypericum; Kaempferols; Male; Methysergide; Muscle Contraction; Muscle, Smooth; Naloxone; Perylene; Phentolamine; Phloroglucinol; Piperidines; Plant Extracts; Propranolol; Pyrazoles; Quercetin; Rats; Rats, Wistar; Rimonabant; Rutin; Terpenes; Tetrodotoxin; Urinary Bladder; Urinary Incontinence; Verapamil | 2004 |
[Quantitative analysis of active substances in St. John's wort (Hypericum perforatum L.) by the high performance liquid chromatography method].
Topics: Anthracenes; Antidepressive Agents; Chromatography, High Pressure Liquid; Flavonoids; Humans; Hypericum; Perylene; Quercetin; Rutin; Time Factors | 2004 |
Comparative chemical composition and variability of biological activity of methanolic extracts from Hypericum perforatum L.
Topics: Anthracenes; Chromatography, High Pressure Liquid; Hypericum; Methanol; Microbial Sensitivity Tests; Perylene; Plant Extracts; Quercetin; Rutin; Solvents | 2005 |
[Evaluation of preparing process of extract of hypericum perforatum using HPLC fingerprint analysis].
Topics: Anthracenes; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavonoids; Hypericum; Perylene; Plant Components, Aerial; Plants, Medicinal; Quality Control; Quercetin; Rutin; Technology, Pharmaceutical | 2006 |
A mechanistic study on altered pharmacokinetics of irinotecan by St. John's wort.
Topics: Animals; Anthracenes; Antineoplastic Agents, Phytogenic; Bridged Bicyclo Compounds; Camptothecin; Cell Line, Tumor; Cell Proliferation; Glucuronides; Hypericum; Irinotecan; Male; Microsomes, Liver; Perylene; Phloroglucinol; Plant Extracts; Quercetin; Rats; Rats, Sprague-Dawley; Terpenes | 2007 |
Antiinflammatory and antioxidant activity of Hypericum rumeliacum Boiss. subsp. apollinis (Boiss. & Heldr.) Robson & Strid methanol extract.
Topics: Animals; Anthracenes; Anti-Inflammatory Agents; Antioxidants; Chlorogenic Acid; Chondrus; Chromatography, High Pressure Liquid; Edema; Flavonoids; Hindlimb; Hypericum; Male; Methanol; Perylene; Phenols; Plant Components, Aerial; Plant Extracts; Polyphenols; Quercetin; Rats; Rats, Wistar; Rutin | 2008 |
[Studies on the chemical constituents of flowers of Prunus mume].
Topics: Anthracenes; Benzoic Acid; Flavonols; Flowers; Molecular Structure; Perylene; Plants, Medicinal; Prunus; Quercetin | 2008 |
Chemical constituents of Hypericum adenotrichum Spach, an endemic Turkish species.
Topics: Anthracenes; Bridged Bicyclo Compounds; Chromatography, High Pressure Liquid; Hypericum; Kaempferols; Perylene; Phloroglucinol; Quercetin; Terpenes; Turkey | 2009 |
A prolonged protein kinase C-mediated, opioid-related antinociceptive effect of st John's Wort in mice.
Topics: Acetic Acid; Analgesics; Analgesics, Opioid; Animals; Anthracenes; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Compounding; Hypericum; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Pain Threshold; Perylene; Phorbol Esters; Phytotherapy; Protein Kinase C; Quercetin; Somatostatin; Spectrometry, Mass, Electrospray Ionization; Statistics, Nonparametric; Time Factors | 2010 |
Secondary metabolites of Hypericum confertum and their possible chemotaxonomic significance.
Topics: Anthracenes; Apigenin; Biflavonoids; Bridged Bicyclo Compounds; Chlorogenic Acid; Hypericum; Perylene; Phloroglucinol; Plant Components, Aerial; Quercetin; Rutin; Terpenes | 2010 |
Pharmacological studies on Hypericum perforatum fractions and constituents.
Topics: Animals; Anthracenes; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Female; Guinea Pigs; Hypericum; In Vitro Techniques; Male; Perylene; Phloroglucinol; Phosphodiesterase Inhibitors; Plant Extracts; Quercetin; Rabbits; Terpenes; Verapamil | 2011 |
Inhibition of 17β-estradiol activation by CYP1A1: genotype- and regioselective inhibition by St. John's Wort and several natural polyphenols.
Topics: Amino Acid Substitution; Anthracenes; Anti-Inflammatory Agents, Non-Steroidal; Biocatalysis; Cytochrome P-450 CYP1A1; Dose-Response Relationship, Drug; Estradiol; Flavonoids; Flavonols; Genotype; Humans; Hydroxylation; Hypericum; Perylene; Phenols; Plant Extracts; Polyphenols; Quercetin; Recombinant Proteins; Resveratrol; Stereoisomerism; Stilbenes; Substrate Specificity | 2011 |
Biphasic dose-response of antioxidants in hypericin-induced photohemolysis.
Topics: Algorithms; Anthracenes; Antioxidants; Ascorbic Acid; Calcium Channels; Dose-Response Relationship, Drug; Erythrocytes; Hemolysis; Humans; Male; Peroxidases; Perylene; Photosensitizing Agents; Protein Kinase C; Quercetin; Reactive Oxygen Species; Superoxide Dismutase; Time Factors | 2011 |
[Chemical constituents of ethyl acetate fraction from Hypericum hengshanense].
Topics: Acetates; Anthracenes; Hypericum; Kaempferols; Magnetic Resonance Spectroscopy; Perylene; Plant Components, Aerial; Plants, Medicinal; Quercetin; Rutin | 2013 |
Hypericum perforatum Reduces Paracetamol-Induced Hepatotoxicity and Lethality in Mice by Modulating Inflammation and Oxidative Stress.
Topics: Acetaminophen; Alanine Transaminase; Animals; Anthracenes; Anti-Inflammatory Agents; Antioxidants; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Glutathione; Hypericum; Inflammation; Male; Mice; Oxidative Stress; Perylene; Phloroglucinol; Plant Extracts; Plants, Medicinal; Quercetin; Rutin; Terpenes; Tumor Necrosis Factor-alpha | 2015 |
Permeation Characteristics of Hypericin across Caco-2 Monolayers in the Absence or Presence of Quercitrin - A Mass Balance Study.
Topics: Anthracenes; Biological Transport; Caco-2 Cells; Cell Membrane; Cell Survival; Humans; Hypericum; Molecular Structure; Molecular Weight; Perylene; Quercetin; Solubility | 2015 |
[Pharmacognosy study of Verbascum species].
Topics: Anthracenes; Chromatography, Thin Layer; Flavonoids; Flowers; Hemolysis; Perylene; Pharmacognosy; Plants, Medicinal; Quercetin; Rutin; Saponins; Verbascum | 2015 |
Optimized and Validated HPLC Analysis of St. John's Wort Extract and Final Products by Simultaneous Determination of Major Ingredients.
Topics: Anthracenes; Chlorogenic Acid; Chromatography, High Pressure Liquid; Drug Stability; Hypericum; Linear Models; Perylene; Plant Extracts; Quercetin; Reproducibility of Results; Rutin; Sensitivity and Specificity | 2017 |
Methodological aspects of biologically active compounds quantification in the genus Hypericum.
Topics: Anthracenes; Catechin; Chlorogenic Acid; Chromatography, High Pressure Liquid; Hypericum; Perylene; Phloroglucinol; Plant Extracts; Plant Leaves; Plant Stems; Quercetin; Rutin; Terpenes | 2018 |
St John's wort extract influences membrane fluidity and composition of phosphatidylcholine and phosphatidylethanolamine in rat C6 glioblastoma cells.
Topics: Animals; Anthracenes; Cell Line, Tumor; Cell Membrane; Glioblastoma; Hydrocortisone; Hypericum; Membrane Fluidity; Perylene; Phloroglucinol; Phosphatidylethanolamines; Plant Extracts; Quercetin; Rats; Receptors, Adrenergic, beta-1; Signal Transduction; Terpenes | 2019 |
Development of new and validated HPTLC methods for the qualitative and quantitative analysis of hyperforin, hypericin and hyperoside contents in Hypericum species.
Topics: Anthracenes; Chromatography, Thin Layer; Hypericum; Perylene; Phloroglucinol; Plant Extracts; Quercetin; Terpenes | 2022 |