Compounds > hyoscyamine
Page last updated: 2024-09-04

hyoscyamine and sildenafil

hyoscyamine has been researched along with sildenafil in 1 studies

Compound Research Comparison

Studies
(hyoscyamine)		Trials
(hyoscyamine)		Recent Studies (post-2010)
(hyoscyamine)		Studies
(sildenafil)		Trials
(sildenafil)		Recent Studies (post-2010) (sildenafil)
99155134060

Protein Interaction Comparison

ProteinTaxonomyhyoscyamine (IC50)sildenafil (IC50)
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)20
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)20
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)20
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)20
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)20
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)20
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)20
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)20
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)20
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)20
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)20
Chain B, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)20
Chain A, cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)20
Chain A, cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)20
Chain A, cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)0.0024
Chain A, cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)0.0024
Phosphodiesterase Bos taurus (cattle)9.2
cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)2.881
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit deltaHomo sapiens (human)0.0187
cGMP-specific 3',5'-cyclic phosphodiesteraseRattus norvegicus (Norway rat)0.0012
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8AHomo sapiens (human)2.881
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)0.2626
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9AHomo sapiens (human)4.2
cGMP-specific 3',5'-cyclic phosphodiesteraseCanis lupus familiaris (dog)0.0024
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammaBos taurus (cattle)0.0374
Replicase polyprotein 1abSevere acute respiratory syndrome-related coronavirus8.247
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 28.247
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alphaBos taurus (cattle)0.0545
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A Bos taurus (cattle)0.78
cAMP-specific 3',5'-cyclic phosphodiesterase 4D Rattus norvegicus (Norway rat)4.6
cAMP-specific 3',5'-cyclic phosphodiesterase 4CRattus norvegicus (Norway rat)4.6
cAMP-specific 3',5'-cyclic phosphodiesterase 4BRattus norvegicus (Norway rat)4.6
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alphaHomo sapiens (human)0.0187
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'Bos taurus (cattle)0.0366
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammaHomo sapiens (human)0.0187
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammaBos taurus (cattle)0.0374
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit betaBos taurus (cattle)0.0374
cAMP-specific 3',5'-cyclic phosphodiesterase 4AHomo sapiens (human)7.9333
Adenosine receptor A2aHomo sapiens (human)0.253
Adenosine receptor A1Homo sapiens (human)1.493
Delta-type opioid receptorRattus norvegicus (Norway rat)0.04
Prostaglandin G/H synthase 2Homo sapiens (human)0.003
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit betaHomo sapiens (human)0.0187
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'Homo sapiens (human)0.0418
cAMP-specific 3',5'-cyclic phosphodiesterase 4ARattus norvegicus (Norway rat)4.6
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1AHomo sapiens (human)0.7199
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammaCanis lupus familiaris (dog)0.0182
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BBos taurus (cattle)0.78
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BHomo sapiens (human)1.8841
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BRattus norvegicus (Norway rat)0.3
Synaptic vesicular amine transporterRattus norvegicus (Norway rat)0.01
cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)6.3336
cAMP-specific 3',5'-cyclic phosphodiesterase 4CHomo sapiens (human)8.52
cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)5.7005
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)3.3075
cGMP-inhibited 3',5'-cyclic phosphodiesterase BHomo sapiens (human)4.7337
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7AHomo sapiens (human)4.69
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammaHomo sapiens (human)0.0187
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1CHomo sapiens (human)0.7398
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)4.6677
cGMP-specific 3',5'-cyclic phosphodiesteraseBos taurus (cattle)0.557
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1CRattus norvegicus (Norway rat)0.3
Indoleamine 2,3-dioxygenase 2Mus musculus (house mouse)4.5
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit deltaBos taurus (cattle)0.0374
Phosphodiesterase Rattus norvegicus (Norway rat)0.3
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11AHomo sapiens (human)4.1584
cAMP-specific 3',5'-cyclic phosphodiesterase 7BHomo sapiens (human)3.6006
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10AHomo sapiens (human)4.2432

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1

Other Studies

1 other study(ies) available for hyoscyamine and sildenafil

ArticleYear
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012