hyoscyamine has been researched along with n-methylscopolamine in 1 studies
| Studies (hyoscyamine) | Trials (hyoscyamine) | Recent Studies (post-2010) (hyoscyamine) | Studies (n-methylscopolamine) | Trials (n-methylscopolamine) | Recent Studies (post-2010) (n-methylscopolamine) |
|---|---|---|---|---|---|
| 99 | 1 | 55 | 1,026 | 12 | 52 |
| Protein | Taxonomy | hyoscyamine (IC50) | n-methylscopolamine (IC50) |
|---|---|---|---|
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.335 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 0.0023 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 0.0023 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 0.0018 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 0.0011 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bermudez, M; Holzgrabe, U; Klöckner, J; Kostenis, E; Mohr, K; Schmitz, J; Schrage, R; Tränkle, C; van der Mey, D; Wolber, G | 1 |
1 other study(ies) available for hyoscyamine and n-methylscopolamine
| Article | Year |
|---|---|
Dualsteric muscarinic antagonists--orthosteric binding pose controls allosteric subtype selectivity.
Topics: Allosteric Regulation; Animals; Atropine Derivatives; Binding Sites; CHO Cells; Cricetulus; Drug Inverse Agonism; Humans; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Muscarinic Agonists; Muscarinic Antagonists; Mutation; Naphthalimides; Phthalimides; Radioligand Assay; Receptor, Muscarinic M2; Scopolamine Derivatives; Stereoisomerism; Structure-Activity Relationship | 2014 |