hymecromone and amentoflavone

hymecromone has been researched along with amentoflavone* in 1 studies

Other Studies

1 other study(ies) available for hymecromone and amentoflavone

Article	Year
Amentoflavone is a potent broad-spectrum inhibitor of human UDP-glucuronosyltransferases. Chemico-biological interactions, 2018, Mar-25, Volume: 284 Amentoflavone (AMF), an abundant natural biflavonoid found in many medicinal plants, displays various beneficial effects including anti-inflammatory, anti-oxidative and anti-cancer. Despite the extensive studies on pharmacological activities, the toxicity or undesirable effects of AMF are rarely reported. In this study, the inhibitory effects of AMF on human UDP-glucuronosyltransferases (UGTs) were carefully investigated. AMF displayed strong inhibition towards most of human UGTs including UGT1A1, 1A3, 1A4, 1A6, 1A7, 1A8, 1A9, 1A10, 2B4 and 2B17, with the IC Topics: Biflavonoids; Chromatography, High Pressure Liquid; Glucuronosyltransferase; Humans; Hymecromone; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Propofol; Recombinant Proteins	2018

Article

Year

Amentoflavone is a potent broad-spectrum inhibitor of human UDP-glucuronosyltransferases.

Chemico-biological interactions, 2018, Mar-25, Volume: 284

Amentoflavone (AMF), an abundant natural biflavonoid found in many medicinal plants, displays various beneficial effects including anti-inflammatory, anti-oxidative and anti-cancer. Despite the extensive studies on pharmacological activities, the toxicity or undesirable effects of AMF are rarely reported. In this study, the inhibitory effects of AMF on human UDP-glucuronosyltransferases (UGTs) were carefully investigated. AMF displayed strong inhibition towards most of human UGTs including UGT1A1, 1A3, 1A4, 1A6, 1A7, 1A8, 1A9, 1A10, 2B4 and 2B17, with the IC

Topics: Biflavonoids; Chromatography, High Pressure Liquid; Glucuronosyltransferase; Humans; Hymecromone; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Propofol; Recombinant Proteins

2018