hydroxyzine and perphenazine

hydroxyzine has been researched along with perphenazine in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199014 (53.85)18.7374
1990's0 (0.00)18.2507
2000's4 (15.38)29.6817
2010's7 (26.92)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Ahman, M; Holmén, AG; Wan, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Balogh, I; Kim, HY; Koczok, K; Korade, Z; Liu, W; Mirnics, K; Porter, NA; Tallman, KA; Xu, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jadhav, A; Kerns, E; Nguyen, K; Shah, P; Sun, H; Xu, X; Yan, Z; Yu, KR1
Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR1
Kabir, M; Kerns, E; Neyra, J; Nguyen, K; Nguyễn, ÐT; Shah, P; Siramshetty, VB; Southall, N; Williams, J; Xu, X; Yu, KR1
Ueda, I; Wada, T1
Downing, RW1
Apogi, E; Ascione, J; Cetin, M; Cottle, B; Fazio, A; Zilite, M1
Matsumiya, T1
Elliott, RC2
Ibrahim, I; Sulman, FG; Weller, CP1
Elliott, RC; Quilliam, JP2
DOBKIN, AB; ISRAEL, JS1
HIRASHIMA, T1
HUANG, TF1
PIUCK, CL1
GORDON, EM; NELSON, HB1

Reviews

1 review(s) available for hydroxyzine and perphenazine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for hydroxyzine and perphenazine

ArticleYear
Clinical evaluation of perphenazine triflupromazine and hydroxyzine for postoperative sedation in children.
    Current therapeutic research, clinical and experimental, 1966, Volume: 8, Issue:1

    Topics: Child; Child, Preschool; Clinical Trials as Topic; Female; Humans; Hydroxyzine; Hypnotics and Sedatives; Infant; Male; Perphenazine; Placebos; Postoperative Care; Tonsillectomy; Triflupromazine

1966

Other Studies

24 other study(ies) available for hydroxyzine and perphenazine

ArticleYear
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
The Effect of Small Molecules on Sterol Homeostasis: Measuring 7-Dehydrocholesterol in Dhcr7-Deficient Neuro2a Cells and Human Fibroblasts.
    Journal of medicinal chemistry, 2016, Feb-11, Volume: 59, Issue:3

    Topics: Animals; Cell Line; Dehydrocholesterols; Dose-Response Relationship, Drug; Fibroblasts; Homeostasis; Humans; Mice; Molecular Conformation; Neurons; Oxidoreductases Acting on CH-CH Group Donors; Small Molecule Libraries; Sterols; Structure-Activity Relationship

2016
Highly predictive and interpretable models for PAMPA permeability.
    Bioorganic & medicinal chemistry, 2017, 02-01, Volume: 25, Issue:3

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Humans; Models, Biological; Organic Chemicals; Regression Analysis; Support Vector Machine

2017
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
    Bioorganic & medicinal chemistry, 2019, 07-15, Volume: 27, Issue:14

    Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility

2019
Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.
    Scientific reports, 2020, 11-26, Volume: 10, Issue:1

    Topics: Animals; Computer Simulation; Databases, Factual; Drug Discovery; High-Throughput Screening Assays; Liver; Machine Learning; Male; Microsomes, Liver; National Center for Advancing Translational Sciences (U.S.); Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Retrospective Studies; United States

2020
Determination of inorganic phosphate by the molybdovanadate method in the presence of ATP and some interfering organic bases.
    Analytical biochemistry, 1970, Volume: 37, Issue:1

    Topics: Adenosine Triphosphate; Alcohols; Anesthetics, Local; Chlorpromazine; Diazepam; Haloperidol; Hydroxyzine; Lidocaine; Methods; Molybdenum; Perphenazine; Phenothiazines; Phosphates; Procaine; Prochlorperazine; Spectrophotometry; Tranquilizing Agents; Trichloroacetic Acid; Vanadium

1970
Mixed anxiety-depression. Fact or myth?
    Archives of general psychiatry, 1974, Volume: 30, Issue:3

    Topics: Adult; Amitriptyline; Anxiety Disorders; Barbiturates; Chlordiazepoxide; Depression; Doxepin; Female; Humans; Hydroxyzine; Interview, Psychological; Male; Middle Aged; Perphenazine; Personality Inventory; Prognosis

1974
[Effects of centrally acting drugs on spinal reflex potentials].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1972, Volume: 68, Issue:2

    Topics: Alkaloids; Aminobutyrates; Animals; Cats; Chlorpromazine; Depression, Chemical; Diazepam; Haloperidol; Hydroxyzine; Imipramine; Indoles; Male; Methotrimeprazine; Monoamine Oxidase Inhibitors; Perphenazine; Prochlorperazine; Pyridines; Reflex; Reflex, Monosynaptic; Spinal Cord; Thiothixene; Tranquilizing Agents

1972
The action of central depressant drugs on the spontaneous discharge of action potentials in the superior cervical sympathetic trunk of the cat.
    Neuropharmacology, 1970, Volume: 9, Issue:2

    Topics: Action Potentials; Animals; Benactyzine; Cats; Cervical Plexus; Chlorpromazine; Ganglia, Autonomic; Hydroxyzine; Pentobarbital; Perphenazine; Procaine; Sympathetic Nervous System; Tranquilizing Agents

1970
Analgesic profile of tranquillizers in multiple screening tests in mice.
    Archives internationales de pharmacodynamie et de therapie, 1968, Volume: 176, Issue:1

    Topics: Acetaminophen; Aminopyrine; Analgesics; Animals; Aspirin; Chlorpromazine; Codeine; Diazepam; Diphenhydramine; Electric Stimulation; Haloperidol; Hot Temperature; Hydroxyzine; Imipramine; Isocarboxazid; Male; Meprobamate; Mice; Morphine; Perphenazine; Phenobarbital; Phenothiazines; Promazine; Promethazine; Reserpine; Tetrabenazine; Thiopental; Time Factors; Tranquilizing Agents

1968
Centrally-active drugs and the discharge rate of spontaneously occurring action potentials in the superior cervical trunk of the cat.
    British journal of pharmacology, 1968, Volume: 34, Issue:3

    Topics: Action Potentials; Animals; Cats; Ganglia, Autonomic; Hydroxyzine; Perphenazine; Phenobarbital

1968
Centrally active drugs and the medullary vasopressor response of the cat; a method of distinguishing between drug actions on the central and peripheral parts of the sympathetic nervous system.
    International journal of neuropharmacology, 1969, Volume: 8, Issue:2

    Topics: Adrenalectomy; Animals; Atropine; Benactyzine; Blood Pressure; Carbamates; Cats; Chlorpromazine; Dextrans; Electric Stimulation; Femoral Artery; Hydroxyzine; Medulla Oblongata; Methods; Perphenazine; Piperidines; Pressoreceptors; Prochlorperazine; Promazine; Sympathetic Nervous System; Temperature; Tranquilizing Agents

1969
The effect of SA 97, perphenazine, and hydroxyzine on epinephrine-induced cardiac arrhythmias during methoxyflurane anaesthesia in dogs.
    Canadian Anaesthetists' Society journal, 1962, Volume: 9

    Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Animals; Anti-Allergic Agents; Arrhythmias, Cardiac; Dogs; Epinephrine; Ethers; Histamine H1 Antagonists; Hydroxyzine; Methoxyflurane; Pain Management; Perphenazine

1962
[Pharmacological studies on the central nervous system by means of experimental perfusion of the cerebral ventricles and subarachnoid space. II. Changes in the respiration, blood pressure and the amount of fluid caused by injection of perfusion solutions
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1962, Mar-20, Volume: 58

    Topics: Blood Pressure; Brain; Cerebral Ventricles; Chlorpromazine; Hydroxyzine; Perfusion; Perphenazine; Respiration; Subarachnoid Space

1962
Studies on prevention and abolition of fibrillation of the cat's heart by drugs.
    Archives internationales de pharmacodynamie et de therapie, 1963, Jan-01, Volume: 141

    Topics: Animals; Arrhythmias, Cardiac; Atrial Fibrillation; Brugada Syndrome; Cardiac Conduction System Disease; Cats; Chlorpromazine; Epinephrine; Felis; Heart Conduction System; Hydroxyzine; Meclizine; Niacinamide; Perphenazine; Prednisolone; Quinidine; Reserpine; Succinates

1963
CLINICAL IMPRESSIONS OF HYDROXYZINE AND OTHER TRANQUILIZERS IN A CHILD GUIDANCE CLINIC.
    Diseases of the nervous system, 1963, Volume: 24

    Topics: Adolescent; Child; Child Behavior Disorders; Child Guidance Clinics; Chlordiazepoxide; Chlorpromazine; Humans; Hydroxyzine; Meprobamate; Perphenazine; Thioridazine; Tranquilizing Agents; Trifluoperazine

1963
SOME ACTIONS OF CENTRALLY ACTIVE AND OTHER DRUGS ON THE TRANSMISSION OF SINGLE NERVE IMPULSES THROUGH THE ISOLATED SUPERIOR CERVICAL GANGLION PREPARATION OF THE RABBIT.
    British journal of pharmacology and chemotherapy, 1964, Volume: 23

    Topics: Action Potentials; Animals; Barbiturates; Benactyzine; Chlorpromazine; Chlorprothixene; Ganglia, Autonomic; Ganglionic Blockers; Hexamethonium Compounds; Hydroxyzine; Hypnotics and Sedatives; Meprobamate; Neural Conduction; Paraldehyde; Perphenazine; Pharmacology; Piperidines; Procaine; Prochlorperazine; Promazine; Promethazine; Rabbits; Research; Superior Cervical Ganglion

1964
A DOUBLE BLIND STUDY OF THE EFFECT OF TRANQUILIZERS DURING LABOR.
    American journal of obstetrics and gynecology, 1965, Jun-01, Volume: 92

    Topics: Anesthesia; Anesthesia, Obstetrical; Biomedical Research; Double-Blind Method; Drug Therapy; Female; Humans; Hydroxyzine; Labor, Obstetric; Meperidine; Obstetrics; Perphenazine; Pregnancy; Scopolamine

1965