hydroxyzine and histamine

hydroxyzine has been researched along with histamine in 74 studies

Research

Studies (74)

Timeframe	Studies, this research(%)	All Research%
pre-1990	41 (55.41)	18.7374
1990's	21 (28.38)	18.2507
2000's	7 (9.46)	29.6817
2010's	4 (5.41)	24.3611
2020's	1 (1.35)	2.80

Authors

Authors	Studies
Bakker, RA; Leurs, R; Lim, HD; Ling, P; Thurmond, RL; van Rijn, RM	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Ahmed, AR; Arnold, AJ; Jones, HE; Simpson, JG	1
Barlier, J; Borgo, J; Chastel, A; Fossard, JM; Kim, KM; Laxenaire, MC; Medot, A	1
Cohan, R; Leifer, KN; Rhoades, RB; Wittig, HJ	1
Braunstein, G; Fajac, I; Frossard, N; Malaquin, F; Melac, M	1
Ghys, L; Mühlethaler, K; Rihoux, JP; Wüthrich, B	1
Cappugi, P; Lotti, T; Tsampau, D	1
Hill, S; Lever, LR; Marks, R; Rosenberg, R; Thompson, D	1
De Vos, C; Ghosh, SK; McIlroy, I; Patel, KR	1
Advenier, C; Candenas, ML; De Vos, C; Naline, E	1
Humphreys, F; Hunter, JA	1
Brummer-Korvenkontio, H; Coulie, P; Lappalainen, P; Palosuo, T; Reunala, T	1
Despontin, K; Ghys, L; Lachapelle, JM; Rihoux, JP; Rivest, J	1
Candito, M; Grimaud, D; Lapalus, P; Occelli, G; Philip, F; Raucoules, M	1
Juhlin, L; Rihoux, JP	1
Dy, M; Piquet-Pellorce, C; Schneider, E	1
Coulie, P; Ghys, L; Rihoux, JP	1
McMillan, JL; Simons, FE; Simons, KJ	1
Rafferty, P	1
De Vos, C; Dubertret, L; Michel, L	1
Grimaud, D; Occelli, G; Raucoules, M	1
Grilliat, JP	1
Antoine, JL; Ghys, L; Rihoux, JP; Van Neste, D	1
Freidhoff, L; Kagey-Sobotka, A; Lichtenstein, LM; Naclerio, RM; Norman, PS; Proud, D	1
Herakleous, M; Kontou-Fili, K; Paleologos, G	1
Chen, XY; Minuk, GY; Simons, FE; Simons, KJ; Watson, WT	1
Rihoux, JP; Van Neste, DJ	1
Berkebile, C; Bradley, D; Kettelhut, BV; Metcalfe, DD	1
Barbet, JL; Halliwell, RE	1
Brik, A; Dauphinee, B; Gong, H; Lee, E; Tashkin, DP	1
Fadel, R; Henocq, E; Herpin-Richard, N; Rihoux, JP	1
Dabronzo, J; Gengo, FM; Love, S; Miller, JK; Yurchak, A	1
Wasserman, SI	1
Kutvirt, SG; Potter, JW; Van Epps, DE	1
Maddox, DE; Reed, CE	1
Brik, A; Gong, H; Tashkin, DP	1
Doyle, W; Fireman, P; Skoner, D; Tanner, E	1
Benveniste, J; Burtin, C; De Vos, C; Dubertret, L; Michel, L; Rihoux, JP	1
Bloom, M; Dupont, P; Pechadre, JC; Rihoux, JP; Trolese, JF; Vernay, D	1
Rihoux, JP; Van Neste, D	1
Baltes, E; De Vos, C; Gobert, J; Maleux, MR	1
Botha, JJ; Groenewoud, G; Luus, HG; Müller, FO; van Dyk, M	1
Gendreau-Reid, L; Simons, FE; Simons, KJ	1
Ashbaugh, P; Mansfield, LE; Rauls, DO; Ting, S	1
Leyden, JJ; Soschin, D	1
Brandes, LJ; Kroeger, EA	1
Boroş, I; Cîrstea, M; Suhaciu, G	1
Kaniike, K; Kurogochi, Y	1
Atkins, P; Green, GR; Zweiman, B	1
Gerber, JG; Nies, AS	1
Harvey, RP; Schocket, AL; Wegs, J	1
Kaliner, M; Ottesen, EA; Shelhamer, JH	1
Garafalo, J; Kaplan, AP	1
Bowman, S; Casale, TB; Kaliner, M	1
Kaplan, AP	1
Polderman, J; Rihoux, JP	1
Kaliner, M; Shelhamer, JH; Sigler, R; Summers, R	1
Bock, SA; Davis, RS; Remigio, LK; Schocket, AL	1
Chan, KH; Swarts, JD; Tan, L	1
Manolidis, LS; Manolidis, SS; Theoharides, TC; Vliagoftis, H	1
Fraser, TG; Reggin, JD; Roberts, JR; Simons, FE; Simons, KJ	1
Kennedy, BP; Mahata, SK; O'Connor, DT; Ziegler, MG	1
Braun, M; Lowitt, MH	1
KRSTIC, M; MIHAJLOVIC, L; VARAGIC, V	1
Elzainy, AA; Gu, X; Simons, FE; Simons, KJ	1
Barbanoj, MJ; García-Gea, C; Izquierdo, I; Jané, F; Morte, A; Pérez, I	1
Antonijoan, RM; Barbanoj, MJ; García-Gea, C; Martínez-Colomer, J; Valiente, R	1
dos Santos, RV; Lima, HC; Magerl, M; Mlynek, A	1
Bäumer, W; Kietzmann, M; Olivry, T; Paps, J; Petersen, LJ; Sander, K; Stahl, J; Stark, H	1
Ibrahim Soliman, I; latif Aziz, R; Zaki Rizkalla, CM	1
Conen, S; Ramaekers, JG; Sambeth, A; Theunissen, EL; Vermeeren, A	1
Egger, JIM; Janssen, PKC; van Haeringen, A; Verhoeven, WMA	1

Reviews

4 review(s) available for hydroxyzine and histamine

Article	Year
[Changes in plasma histamine and catecholamines levels after injection of chymopapain in chemonucleolysis]. Annales francaises d'anesthesie et de reanimation, 1991, Volume: 10, Issue:6 Topics: Adult; Basophil Degranulation Test; Catecholamines; Chymopapain; Drug Hypersensitivity; Female; Histamine; Humans; Hydroxyzine; Intervertebral Disc Chemolysis; Male; Middle Aged; Premedication; Prospective Studies; Radioallergosorbent Test; Skin Tests; Tranexamic Acid	1991
Antihistamines in the treatment of clinical asthma. The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:4 Pt 2 Topics: Animals; Asthma; Benzhydryl Compounds; Cetirizine; Dose-Response Relationship, Drug; Forced Expiratory Volume; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity, Delayed; Peak Expiratory Flow Rate; Phthalazines; Terfenadine	1990
Middle ear mucosal inflammation: an in vivo model. The Laryngoscope, 1994, Volume: 104, Issue:8 Pt 1 Topics: Animals; Capillary Permeability; Chinchilla; Contrast Media; Dexamethasone; Dose-Response Relationship, Drug; Ear, Middle; Extravasation of Diagnostic and Therapeutic Materials; Gadolinium; Gadolinium DTPA; Histamine; Humans; Hydroxyzine; Inflammation; Magnetic Resonance Imaging; Mucous Membrane; Organometallic Compounds; Otitis Media; Pentetic Acid; Ranitidine; Vasoconstrictor Agents; Vasomotor System	1994
Pruritus. Advances in dermatology, 2001, Volume: 17 Topics: Acupuncture; Administration, Topical; Anti-Inflammatory Agents; Antipruritics; Combined Modality Therapy; Glucocorticoids; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Ondansetron; Pruritus; PUVA Therapy	2001

Trials

33 trial(s) available for hydroxyzine and histamine

Article	Year
Suppression of histamine-induced pruritus by hydroxyzine and various neuroleptics. Journal of the American Academy of Dermatology, 1979, Volume: 1, Issue:6 Topics: Adult; Antipsychotic Agents; Clinical Trials as Topic; Double-Blind Method; Histamine; Humans; Hydroxyzine; Placebos; Pruritus	1979
Suppression of histamine-induced pruritus by three antihistaminic drugs. The Journal of allergy and clinical immunology, 1975, Volume: 55, Issue:3 Topics: Adolescent; Adult; Clinical Trials as Topic; Cyproheptadine; Differential Threshold; Diphenhydramine; Dose-Response Relationship, Drug; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Lactose; Placebos; Pruritus	1975
Inhibition of histamine-induced nasal obstruction by cetirizine in allergic rhinitis. British journal of clinical pharmacology, 1992, Volume: 33, Issue:4 Topics: Adult; Airway Resistance; Cetirizine; Female; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Nasal Mucosa; Nasal Obstruction; Rhinitis, Allergic, Seasonal	1992
The skin as a target organ for the investigation of antiallergic drugs: comparison between cetirizine and terfenadine. Dermatology (Basel, Switzerland), 1992, Volume: 184, Issue:2 Topics: Adolescent; Adult; Antigens; Cetirizine; Dermatitis; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity, Immediate; Male; Middle Aged; Skin Tests; Terfenadine	1992
Effects of cetirizine, loratadine and terfenadine on histamine weal and flare reactions. Skin pharmacology : the official journal of the Skin Pharmacology Society, 1992, Volume: 5, Issue:1 Topics: Administration, Oral; Adult; Cetirizine; Cyproheptadine; Double-Blind Method; Erythema; Female; Histamine; Histamine Antagonists; Humans; Hydroxyzine; Loratadine; Male; Middle Aged; Random Allocation; Skin; Terfenadine	1992
Effect of cetirizine on histamine- and leukotriene D4-induced bronchoconstriction in patients with atopic asthma. The Journal of allergy and clinical immunology, 1991, Volume: 87, Issue:5 Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Cetirizine; Double-Blind Method; Drug Interactions; Female; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Middle Aged; SRS-A; Time Factors	1991
The effects of astemizole, cetirizine and loratadine on the time course of weal and flare reactions to histamine, codeine and antigen. The British journal of dermatology, 1991, Volume: 125, Issue:4 Topics: Adult; Animals; Antigens; Astemizole; Cetirizine; Codeine; Cyproheptadine; Dermatitis, Contact; Dust; Female; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Male; Middle Aged; Mites; Skin; Time Factors	1991
Cutaneous reactivity to mosquito bites: effect of cetirizine and development of anti-mosquito antibodies. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1991, Volume: 21, Issue:5 Topics: Adolescent; Adult; Aedes; Animals; Antigens; Cetirizine; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity, Immediate; Immunoglobulin G; Insect Bites and Stings; Male; Middle Aged; Molecular Weight; Skin	1991
Pharmacological modulation by cetirizine and ebastine of the cutaneous reactivity to histamine. Dermatologica, 1991, Volume: 183, Issue:3 Topics: Administration, Cutaneous; Administration, Oral; Adult; Butyrophenones; Capsules; Cetirizine; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity; Male; Multivariate Analysis; Piperidines; Placebos; Skin; Skin Tests; Time Factors	1991
Compared peripheral H1 inhibiting effects of cetirizine 2 HCl and loratadine. Annals of allergy, 1990, Volume: 65, Issue:2 Topics: Adult; Cetirizine; Cyproheptadine; Double-Blind Method; Drug Hypersensitivity; Female; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity, Immediate; Hypnotics and Sedatives; Loratadine; Male; Middle Aged; Placebos; Randomized Controlled Trials as Topic	1990
A double-blind, single-dose, crossover comparison of cetirizine, terfenadine, loratadine, astemizole, and chlorpheniramine versus placebo: suppressive effects on histamine-induced wheals and flares during 24 hours in normal subjects. The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:4 Pt 1 Topics: Adult; Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Chlorpheniramine; Cyproheptadine; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Male; Placebos; Skin Tests; Terfenadine; Time Factors; Urticaria	1990
Cetirizine effects on the cutaneous allergic reaction in humans. Annals of allergy, 1990, Volume: 65, Issue:6 Topics: Adult; Allergens; Cetirizine; Dermatitis, Atopic; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Skin; Skin Physiological Phenomena	1990
Pharmacological modulation by cetirizine and atropine of the histamine- and methacholine-induced wheals and flares in human skin. Skin pharmacology : the official journal of the Skin Pharmacology Society, 1989, Volume: 2, Issue:2 Topics: Adult; Atropine; Cetirizine; Dermatitis; Double-Blind Method; Female; Galvanic Skin Response; Histamine; Humans; Hydroxyzine; Injections, Intradermal; Male; Methacholine Compounds; Skin; Skin Physiological Phenomena; Sweat	1989
The effect of cetirizine on early allergic response. The Laryngoscope, 1989, Volume: 99, Issue:6 Pt 1 Topics: Albumins; Antigens; Cetirizine; Clinical Trials as Topic; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Nasal Mucosa; Peptide Hydrolases; Prostaglandin D2; Rhinitis, Allergic, Seasonal; Sneezing	1989
Suppression of histamine-induced skin reactions by loratadine and cetirizine diHCl. European journal of clinical pharmacology, 1989, Volume: 36, Issue:6 Topics: Adult; Cetirizine; Cyproheptadine; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Middle Aged; Random Allocation; Skin	1989
Quantitative time course study of the skin response to histamine and the effect of H1 blockers. A 3-week crossover double-blind comparative trial of cetirizine and terfenadine. Dermatologica, 1989, Volume: 179, Issue:3 Topics: Adult; Benzhydryl Compounds; Blood Flow Velocity; Cetirizine; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Intradermal Tests; Lasers; Randomized Controlled Trials as Topic; Regional Blood Flow; Skin; Terfenadine	1989
A double-blind, placebo-controlled, crossover trial of ketotifen versus hydroxyzine in the treatment of pediatric mastocytosis. The Journal of allergy and clinical immunology, 1989, Volume: 83, Issue:5 Topics: Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Female; Histamine; Humans; Hydroxyzine; Infant; Ketotifen; Male; Mastocytosis	1989
Effect of cetirizine, a new histamine H1 antagonist, on airway dynamics and responsiveness to inhaled histamine in mild asthma. The Journal of allergy and clinical immunology, 1987, Volume: 80, Issue:1 Topics: Administration, Inhalation; Adult; Asthma; Bronchi; Bronchial Spasm; Cetirizine; Dose-Response Relationship, Drug; Female; Forced Expiratory Volume; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Middle Aged	1987
Inhibitory effect of cetirizine 2HCl on eosinophil migration in vivo. Clinical allergy, 1987, Volume: 17, Issue:4 Topics: Adult; Cell Movement; Cetirizine; Eosinophils; Female; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; p-Methoxy-N-methylphenethylamine; Pollen; Rhinitis, Allergic, Seasonal; Skin Tests	1987
The relative antihistaminic and psychomotor effects of hydroxyzine and cetirizine. Clinical pharmacology and therapeutics, 1987, Volume: 42, Issue:3 Topics: Adult; Cetirizine; Clinical Trials as Topic; Double-Blind Method; Flicker Fusion; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Kinetics; Male; Motor Activity; Random Allocation; Skin; Sleep Stages	1987
Cetirizine inhibition of histamine-induced bronchospasm. Annals of allergy, 1987, Volume: 59, Issue:6 Pt 2 Topics: Adult; Analysis of Variance; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Bronchodilator Agents; Cetirizine; Dose-Response Relationship, Drug; Female; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Male	1987
Inhibitory effect of oral cetirizine on in vivo antigen-induced histamine and PAF-acether release and eosinophil recruitment in human skin. The Journal of allergy and clinical immunology, 1988, Volume: 82, Issue:1 Topics: Administration, Oral; Adolescent; Adult; Cetirizine; Eosinophils; Female; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity, Immediate; Male; Platelet Activating Factor; Skin	1988
Comparison of the central and peripheral effects of cetirizine and terfenadine. European journal of clinical pharmacology, 1988, Volume: 35, Issue:3 Topics: Adult; Benzhydryl Compounds; Cetirizine; Electroencephalography; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Terfenadine; Time Factors; Urticaria	1988
Inhibition of the cutaneous response to histamine by H1-blocking agents. Quantitative evaluation of microvascular changes in the skin after histamine challenge and a comparison of the effects of a single intake of cetirizine and terfenadine. Skin pharmacology : the official journal of the Skin Pharmacology Society, 1988, Volume: 1, Issue:3 Topics: Adult; Benzhydryl Compounds; Cetirizine; Dermatitis; Double-Blind Method; Erythema; Female; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Injections, Intradermal; Lasers; Male; Microcirculation; Random Allocation; Regional Blood Flow; Rheology; Skin; Terfenadine	1988
Attenuation of cutaneous reactivity to histamine by cetirizine and dexchlorpheniramine. European journal of clinical pharmacology, 1988, Volume: 35, Issue:3 Topics: Adult; Cetirizine; Chlorpheniramine; Delayed-Action Preparations; Double-Blind Method; Fatigue; Female; Histamine; Humans; Hydroxyzine; Urticaria	1988
Comparison of the suppressive effect of astemizole, terfenadine, and hydroxyzine on histamine-induced wheals and flares in humans. The Journal of allergy and clinical immunology, 1986, Volume: 77, Issue:2 Topics: Adult; Astemizole; Benzhydryl Compounds; Benzimidazoles; Dose-Response Relationship, Immunologic; Double-Blind Method; Female; Histamine; Humans; Hydroxyzine; Hypersensitivity, Immediate; Immunosuppressive Agents; Male; Skin Tests; Terfenadine	1986
A controlled trial of therapy in chronic urticaria. The Journal of allergy and clinical immunology, 1981, Volume: 68, Issue:4 Topics: Adult; Chlorpheniramine; Chronic Disease; Cimetidine; Clinical Trials as Topic; Cyproheptadine; Drug Therapy, Combination; Female; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Middle Aged; p-Methoxy-N-methylphenethylamine; Terbutaline; Urticaria	1981
Effects of infused histamine: analysis of the effects of H-1 and H-2 histamine receptor antagonists on cardiovascular and pulmonary responses. The Journal of allergy and clinical immunology, 1981, Volume: 68, Issue:5 Topics: Adult; Blood Pressure; Cardiovascular System; Cimetidine; Female; Guanidines; Histamine; Humans; Hydroxyzine; Male; Peak Expiratory Flow Rate; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Respiratory Function Tests; Skin Physiological Phenomena; Temperature	1981
Treatment of secretory otitis media with local instillation of hydroxyzine. International archives of allergy and immunology, 1994, Volume: 103, Issue:1 Topics: Child; Child, Preschool; Female; Histamine; Humans; Hydroxyzine; Injections; Male; Mast Cells; Otitis Media with Effusion; Prednisolone; Single-Blind Method; Tympanic Membrane	1994
Adverse central nervous system effects of older antihistamines in children. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 1996, Volume: 7, Issue:1 Topics: Child; Cross-Over Studies; Diphenhydramine; Double-Blind Method; Event-Related Potentials, P300; Fatigue; Female; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Rhinitis; Skin; Skin Tests	1996
Central and peripheral evaluation of rupatadine, a new antihistamine/platelet-activating factor antagonist, at different doses in healthy volunteers. Neuropsychobiology, 2004, Volume: 50, Issue:4 Topics: Adult; Analysis of Variance; Attention; Cross-Over Studies; Cyproheptadine; Decision Making; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Female; Flicker Fusion; Follow-Up Studies; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Motor Activity; Neuropsychological Tests; Pain Measurement; Platelet Activating Factor; Psychomotor Performance; Reaction Time; Self-Assessment; Skin Tests; Statistics, Nonparametric; Time Factors	2004
Comparison of peripheral and central effects of single and repeated oral dose administrations of bilastine, a new H1 antihistamine: a dose-range study in healthy volunteers with hydroxyzine and placebo as control treatments. Journal of clinical psychopharmacology, 2008, Volume: 28, Issue:6 Topics: Administration, Oral; Adult; Affect; Attention; Benzimidazoles; Cross-Over Studies; Dermatitis, Contact; Dose-Response Relationship, Drug; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Injections, Intradermal; Intradermal Tests; Male; Perception; Piperidines; Psychomotor Performance; Reaction Time; Reference Values; Young Adult	2008
Suppression of histamine- and allergen-induced skin reactions: comparison of first- and second-generation antihistamines. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2009, Volume: 102, Issue:6 Topics: Adult; Allergens; Animals; Dermatophagoides pteronyssinus; Dibenzazepines; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Hydroxyzine; Imidazoles; Loratadine; Male; Middle Aged; Rhinitis, Allergic, Perennial; Skin Tests; Terfenadine; Treatment Outcome; Urticaria	2009

Other Studies

37 other study(ies) available for hydroxyzine and histamine

Article	Year
Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist. The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:3 Topics: Cell Line; Histamine Agonists; Humans; Imidazoles; Indoles; Isothiuronium; Ligands; Methylhistamines; Piperazines; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Receptors, Histamine H4	2005
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
[Prevention of complications of histamine liberation occurring after administration of anesthetic agents and adjuvants]. Annales de l'anesthesiologie francaise, 1977, Volume: 18, Issue:7-8 Topics: Adjuvants, Anesthesia; Aminocaproic Acid; Anaphylaxis; Anesthesia, General; Anesthetics; Drug Hypersensitivity; Histamine; Histamine Antagonists; Histamine Release; Humans; Hydroxyzine; Hypersensitivity, Immediate; Preanesthetic Medication; Risk	1977
Substance P provokes cutaneous erythema and edema through a histamine-independent pathway. International journal of dermatology, 1992, Volume: 31, Issue:3 Topics: Adult; Capsaicin; Edema; Erythema; Female; Histamine; Humans; Hydroxyzine; Male; Middle Aged; p-Methoxy-N-methylphenethylamine; Substance P	1992
The effect of cetirizine on the human isolated bronchus: interaction with salbutamol. The Journal of allergy and clinical immunology, 1991, Volume: 88, Issue:1 Topics: Acetylcholine; Albuterol; Bronchi; Bronchoconstriction; Cetirizine; Dose-Response Relationship, Drug; Drug Synergism; Epithelium; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; In Vitro Techniques; Pyrilamine	1991
Effect of cetirizine on cutaneous reactions to PAF, kallikrein and serum in patients with chronic urticaria. Acta dermato-venereologica, 1990, Volume: 70, Issue:2 Topics: Adult; Blood Transfusion, Autologous; Cetirizine; Chronic Disease; Female; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity, Delayed; Injections, Intradermal; Kallikreins; Male; Middle Aged; Platelet Activating Factor; Urticaria	1990
New role for histamine in interleukin-3-induced proliferation of hematopoietic stem cells. Journal of cellular physiology, 1990, Volume: 143, Issue:2 Topics: Animals; Bone Marrow Cells; Cell Division; Cetirizine; Colony-Forming Units Assay; Dimaprit; Hematopoiesis; Hematopoietic Stem Cells; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Hydroxyzine; Imidazoles; In Vitro Techniques; Interleukin-3; Methylhistidines; Mice; Mice, Inbred C57BL; Thiourea	1990
[Peroperative blood histamine and mastocytosis]. Annales francaises d'anesthesie et de reanimation, 1991, Volume: 10, Issue:1 Topics: Adult; Histamine; Humans; Hydroxyzine; Intraoperative Period; Male; Mastocytosis	1991
[Role of the autonomic nervous system in the modulation of anaphylaxis]. Annales francaises d'anesthesie et de reanimation, 1985, Volume: 4, Issue:2 Topics: Anaphylaxis; Autonomic Nervous System; Histamine; Histamine Release; Humans; Hydroxyzine; Isoproterenol; Phenylephrine	1985
The pharmacokinetics and pharmacodynamics of hydroxyzine in patients with primary biliary cirrhosis. Journal of clinical pharmacology, 1989, Volume: 29, Issue:9 Topics: Adult; Aged; Cetirizine; Chromatography, High Pressure Liquid; Female; Half-Life; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Liver Cirrhosis, Biliary; Male; Middle Aged; Skin Tests	1989
Duration of inhibition of immediate skin test reactivity by hydroxyzine hydrochloride in dogs. Journal of the American Veterinary Medical Association, 1989, Jun-01, Volume: 194, Issue:11 Topics: Allergens; Animals; Dog Diseases; Dogs; Histamine; Hydroxyzine; Hypersensitivity, Immediate; Intradermal Tests; Siphonaptera; Time Factors	1989
Histamine and the preclinical pharmacology of cetirizine. Annals of allergy, 1987, Volume: 59, Issue:6 Pt 2 Topics: Animals; Cetirizine; Dogs; Guinea Pigs; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Mast Cells; Mice; Rats	1987
In vitro effects of cetirizine and histamine on human neutrophil function. Annals of allergy, 1987, Volume: 59, Issue:6 Pt 2 Topics: Cetirizine; Chemotaxis, Leukocyte; Complement C3; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity, Immediate; In Vitro Techniques; Neutrophils; Receptors, Complement; Superoxides	1987
Clinical pharmacodynamics of antihistamines. Annals of allergy, 1987, Volume: 59, Issue:6 Pt 2 Topics: Animals; Asthma; Brain; Bronchial Provocation Tests; Cetirizine; Drug Evaluation; Electroencephalography; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Rhinitis, Allergic, Seasonal; Skin Tests	1987
A primate model for the evaluation of antihistamines. Annals of allergy, 1987, Volume: 59, Issue:6 Pt 2 Topics: Administration, Oral; Airway Resistance; Animals; Bronchial Provocation Tests; Cetirizine; Chlorpheniramine; Drug Evaluation; Histamine; Histamine H1 Antagonists; Hydroxyzine; Macaca mulatta; Manometry; Nose; Rhinitis, Allergic, Seasonal; Skin Tests; Software	1987
Inhibition of histamine and allergen skin wheal by cetirizine in four animal species. Annals of allergy, 1987, Volume: 59, Issue:4 Topics: Allergens; Animals; Benzhydryl Compounds; Cetirizine; Clemastine; Dogs; Female; Guinea Pigs; Histamine; Histamine Antagonists; Hydroxyzine; Hypersensitivity, Immediate; Male; Mice; Mice, Inbred Strains; Pyrilamine; Rats; Rats, Inbred Strains; Skin; Species Specificity; Terfenadine	1987
Ethanol-induced urticaria: a case report. Annals of allergy, 1988, Volume: 60, Issue:6 Topics: Adult; Cytoplasmic Granules; Double-Blind Method; Ethanol; Histamine; Humans; Hydroxyzine; Male; Mast Cells; Skin; Skin Tests; Urticaria	1988
Sorbic acid-induced erythema and edema. Journal of the American Academy of Dermatology, 1986, Volume: 14, Issue:2 Pt 1 Topics: Administration, Topical; Anti-Inflammatory Agents; Aspirin; Betamethasone Valerate; Capsaicin; Cosmetics; Dermatitis, Atopic; Dose-Response Relationship, Drug; Edema; Erythema; Fatty Acids, Unsaturated; Histamine; Humans; Hydrocortisone; Hydroxyzine; Lidocaine; Mast Cells; Pharmaceutic Aids; Preservatives, Pharmaceutical; Sorbic Acid	1986
Evidence that tamoxifen is a histamine antagonist. Biochemical and biophysical research communications, 1985, Sep-16, Volume: 131, Issue:2 Topics: Acetylcholine; Animals; Dogs; Female; Histamine; Histamine Antagonists; Hydroxyzine; Male; Muscle Contraction; Phosphatidylethanolamines; Potassium; Pyrilamine; Serotonin; Tamoxifen; Trachea	1985
Influence of the drugs on the immuno-allergic reactivity. IV. The action of tranquillizers on passive anaphylaxis in guinea-pig. Revue roumaine de morphologie et de physiologie, 1974, Volume: 20, Issue:1 Topics: Anaphylaxis; Animals; Chlordiazepoxide; Drug Evaluation, Preclinical; Guinea Pigs; Histamine; Histamine H1 Antagonists; Hydroxyzine; Imipramine; Meprobamate; Promethazine; Tranquilizing Agents	1974
[Effect of psychotropic drugs on the K + -dependent phosphatase activity in guinea pig brain microsomes]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1972, Volume: 68, Issue:1 Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Chlordiazepoxide; Chlorpromazine; Desipramine; Diazepam; Guinea Pigs; Histamine; Hydroxyzine; Imipramine; Meprobamate; Microsomes; Morphine; Nialamide; Phenelzine; Phenobarbital; Phenoxybenzamine; Phosphoric Monoester Hydrolases; Pilocarpine; Potassium; Procaine; Reserpine; Tranquilizing Agents	1972
Histologic studies of human skin test responses to ragweed, compound 48-80, and histamine. The Journal of allergy and clinical immunology, 1973, Volume: 51, Issue:5 Topics: Adult; Biopsy; Eosinophils; Histamine; Humans; Hydroxyzine; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Pollen; Rhinitis, Allergic, Seasonal; Skin; Skin Tests	1973
The role of prostaglandins in histamine-induced gastric vasodilation in the dog. The Journal of pharmacology and experimental therapeutics, 1980, Volume: 213, Issue:1 Topics: Acetazolamide; Animals; Anti-Inflammatory Agents; Arachidonic Acids; Dimaprit; Dogs; Drug Interactions; Female; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Hydroxyzine; Male; Pharmaceutical Vehicles; Prostaglandins; Pyridines; Receptors, Histamine H1; Receptors, Histamine H2; Stomach; Thiourea; Time Factors; Vasodilation	1980
Effects of infused histamine: correlation of plasma histamine levels and symptoms. The Journal of allergy and clinical immunology, 1982, Volume: 69, Issue:3 Topics: Adult; Blood Pressure; Cimetidine; Female; Headache; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Hydroxyzine; Infusions, Parenteral; Male; Pulse; Skin	1982
Histamine release and therapy of severe dermatographism. The Journal of allergy and clinical immunology, 1981, Volume: 68, Issue:2 Topics: Adolescent; Animals; Cyproheptadine; Diphenhydramine; Female; Histamine; Histamine Release; Humans; Hydroxyzine; Immunization, Passive; Pruritus; Rats; Urticaria	1981
Induction of human cutaneous mast cell degranulation by opiates and endogenous opioid peptides: evidence for opiate and nonopiate receptor participation. The Journal of allergy and clinical immunology, 1984, Volume: 73, Issue:6 Topics: Codeine; Cytoplasmic Granules; Endorphins; Histamine; Humans; Hydroxyzine; Intradermal Tests; Mast Cells; Meperidine; Morphine; Naloxone; Narcotics; Receptors, Opioid; Skin	1984
Exercise-induced hives. The Journal of allergy and clinical immunology, 1984, Volume: 73, Issue:5 Pt 2 Topics: Cimetidine; Cold Temperature; Cyproheptadine; Histamine; Humans; Hydroxyzine; Hypotension; Methacholine Chloride; Methacholine Compounds; Physical Exertion; Skin Temperature; Tripelennamine; Urticaria	1984
The effect of clemastine and hydroxyzine on cutaneous histamine response in man. The Journal of international medical research, 1982, Volume: 10, Issue:5 Topics: Adult; Clemastine; Dermatitis, Atopic; Female; Histamine; Humans; Hydroxyzine; Male; Middle Aged; Pyrrolidines	1982
Evaluation of a patient with both aquagenic and cholinergic urticaria. The Journal of allergy and clinical immunology, 1981, Volume: 68, Issue:6 Topics: Anxiety; Child; Cholinergic Fibers; Female; Heart Rate; Histamine; Hot Temperature; Humans; Hydroxyzine; Physical Exertion; Pruritus; Skin Tests; Temperature; Urticaria; Water	1981
Mechanism of cardiovascular actions of the chromogranin A fragment catestatin in vivo. Peptides, 1998, Volume: 19, Issue:7 Topics: Adrenergic Antagonists; Amino Acid Sequence; Animals; Blood Pressure; Chromogranin A; Chromogranins; Electric Stimulation; Epinephrine; Histamine; Histamine H1 Antagonists; Hydroxyzine; Male; Molecular Sequence Data; Neuropeptide Y; Norepinephrine; Peptide Fragments; Phenoxybenzamine; Propranolol; Protein Structure, Secondary; Rats; Rats, Sprague-Dawley	1998
THE EFFECT OF PSYCHOPHARMACOLOGICAL AGENTS ON THE HYPERTENSIVE RESPONSE TO ESERINE IN THE RAT. International journal of neuropharmacology, 1964, Volume: 3 Topics: Acetylcholine; Blood Pressure; Blood Pressure Determination; Carotid Sinus; Chlordiazepoxide; Histamine; Hydroxyzine; Imipramine; Lysergic Acid Diethylamide; Meprobamate; Norepinephrine; Pharmacology; Physostigmine; Promethazine; Reflex; Research; Thioridazine; Tranquilizing Agents	1964
Hydroxyzine from topical phospholipid liposomal formulations: evaluation of peripheral antihistaminic activity and systemic absorption in a rabbit model. AAPS pharmSci, 2003, Nov-05, Volume: 5, Issue:4 Topics: Animals; Chemistry, Pharmaceutical; Disease Models, Animal; Drug Delivery Systems; Histamine; Histamine H1 Antagonists; Hydroxyzine; Hypersensitivity; Liposomes; Phospholipids; Rabbits; Random Allocation	2003
Lack of preventing effect of systemically and topically administered histamine H(1) or H(4) receptor antagonists in a dog model of acute atopic dermatitis. Experimental dermatology, 2011, Volume: 20, Issue:7 Topics: Aging; Animals; Antigens, Dermatophagoides; Cetirizine; Dermatitis, Atopic; Dermatophagoides farinae; Disease Models, Animal; Dogs; Erythema; Female; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Hydroxyzine; Indoles; Male; Permeability; Piperazines; Skin; Skin Absorption; Triamcinolone	2011
Microencapsulation of hydroxyzine HCl by thermal phase separation: in vitro release enhancement and in vivo pharmacodynamic evaluation. Pharmaceutical development and technology, 2013, Volume: 18, Issue:1 Topics: Administration, Cutaneous; Administration, Oral; Animals; Capsules; Cellulose; Cyclohexanes; Delayed-Action Preparations; Drug Compounding; Excipients; Histamine; Histamine H1 Antagonists; Hydroxyzine; Polyenes; Polymers; Rabbits; Skin Absorption; Starch; Time Factors; Viscosity	2013
Central nervous system-impairing effects of hydroxyzine as a function of histamine availability. Journal of clinical psychopharmacology, 2013, Volume: 33, Issue:2 Topics: Central Nervous System; Evoked Potentials; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Time Factors	2013
Adult male patient with severe intellectual disability caused by a homozygous mutation in the HNMT gene. BMJ case reports, 2020, Dec-12, Volume: 13, Issue:12 Topics: Aggression; Brain; Histamine; Histamine N-Methyltransferase; Homozygote; Humans; Hydroxyzine; Intellectual Disability; Male; Mutation; Sleep; Treatment Outcome; Young Adult	2020