hydroxyzine has been researched along with diphenhydramine in 48 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (43.75) | 18.7374 |
| 1990's | 12 (25.00) | 18.2507 |
| 2000's | 7 (14.58) | 29.6817 |
| 2010's | 6 (12.50) | 24.3611 |
| 2020's | 2 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Carrupt, PA; Jolliet, P; Morin, C; Morin, D; Pagliara, A; Rihoux, JP; Testa, B; Tillement, JP; Urien, S | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Caron, G; Ermondi, G | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Cohan, R; Leifer, KN; Rhoades, RB; Wittig, HJ | 1 |
| Highet, AS; Titterington, DM | 1 |
| Jancelewicz, Z; Sussman, G | 1 |
| Gabos, C; Gengo, FM; Mechtler, L | 1 |
| Berman, BA | 1 |
| Samuels, LL; Sheffer, AL | 1 |
| Karttunen, P; Nuutinen, J; Saano, V; Silvasti, M; Virta, P | 1 |
| O'Brien, DF | 1 |
| von Maur, K | 1 |
| Gabos, C; Gengo, FM | 1 |
| Donovan, JW; Griffen, D | 1 |
| Gault, FP; Yules, RB | 1 |
| Arnold, K; Gerber, N | 1 |
| Hopkins, E; Hruban, Z; Slesers, A | 1 |
| Davis, H | 1 |
| Cook, TJ; Lantos, RL; MacQueen, DM; Thornby, JI; Virtue, CM; Wittig, HJ | 1 |
| Krager, JM; Safer, DJ | 1 |
| Phillips, FJ | 1 |
| Ibrahim, I; Sulman, FG; Weller, CP | 1 |
| Bellows, JG | 1 |
| Goldberg, HL | 1 |
| Garafalo, J; Kaplan, AP | 1 |
| Borish, L; Findlay, SR; Matloff, SM | 1 |
| Greenberger, PA | 1 |
| Pollack, CV; Romano, TJ | 1 |
| Baker, BA; Cacchione, JG | 1 |
| Andersen, JM | 1 |
| Woosley, RL | 1 |
| Fraser, TG; Reggin, JD; Roberts, JR; Simons, FE; Simons, KJ | 1 |
| Annunziato, L; Taglialatela, M; Timmerman, H | 1 |
| Basavaiah, K; Charan, VS | 1 |
| Ihrke, PJ; Kass, PH; White, SD; Zur, G | 1 |
| BOYAJY, LD; WHITE, RP | 1 |
| DEJONG, RH | 1 |
| Joseph, K; Kaplan, AP; Marsland, AM; Soundararajan, S | 1 |
| Garg, R; Husain, N; Roach, CL; Welch, E; Zabinsky, J | 1 |
| Heard, K; Simon, M | 1 |
| Bloom, J; Gnirke, M; Howland, MA; Klein, SS | 1 |
5 review(s) available for hydroxyzine and diphenhydramine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Perennial allergic rhinitis: clinical efficacy of a new antihistamine.
Topics: Benzhydryl Compounds; Cetirizine; Diphenhydramine; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Humans; Hydroxyzine; Rhinitis, Allergic, Perennial; Terfenadine | 1990 |
Cetirizine: antiallergic therapy beyond traditional H1 antihistamines.
Topics: Cetirizine; Diphenhydramine; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity; Reaction Time | 1990 |
Benzodiazepine and nonbenzodiazepine anxiolytics.
Topics: Adrenergic beta-Antagonists; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Anxiety Disorders; Barbiturates; Benzodiazepines; Biotransformation; Diphenhydramine; Ethanol; gamma-Aminobutyric Acid; Glycerol; Humans; Hydroxyzine; Propylene Glycols; Receptors, Cell Surface; Receptors, GABA-A; Spiro Compounds | 1984 |
Cardiac actions of antihistamines.
Topics: Animals; Astemizole; Cetirizine; Diphenhydramine; Drug Interactions; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Terfenadine; Torsades de Pointes | 1996 |
8 trial(s) available for hydroxyzine and diphenhydramine
| Article | Year |
|---|---|
Suppression of histamine-induced pruritus by three antihistaminic drugs.
Topics: Adolescent; Adult; Clinical Trials as Topic; Cyproheptadine; Differential Threshold; Diphenhydramine; Dose-Response Relationship, Drug; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Lactose; Placebos; Pruritus | 1975 |
Controlled trial of H1 antagonists in the treatment of chronic idiopathic urticaria.
Topics: Adult; Aged; Astemizole; Chronic Disease; Diphenhydramine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Middle Aged; Skin Tests; Urticaria | 1991 |
Quantitative effects of cetirizine and diphenhydramine on mental performance measured using an automobile driving simulator.
Topics: Automobile Driving; Cetirizine; Diphenhydramine; Histamine H1 Antagonists; Humans; Hydroxyzine; Psychomotor Performance; Reaction Time; Sleep Stages | 1990 |
Antihistamine selection in patients with allergic rhinitis.
Topics: Chlorpheniramine; Clinical Trials as Topic; Diphenhydramine; Histamine H1 Antagonists; Humans; Hydroxyzine; Patient Participation; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Sleep Stages; Trimeprazine; Tripelennamine | 1985 |
Antihistamines, drowsiness, and psychomotor impairment: central nervous system effect of cetirizine.
Topics: Automobile Driving; Brain; Cetirizine; Clinical Trials as Topic; Diphenhydramine; Double-Blind Method; Histamine H1 Antagonists; Humans; Hydroxyzine; Psychomotor Performance; Random Allocation; Reaction Time; Research Design; Sleep Stages | 1987 |
Degree and duration of skin test suppression and side effects with antihistamines. A double blind controlled study with five antihistamines.
Topics: Adult; Allergens; Chlorpheniramine; Diphenhydramine; Dust; Histamine H1 Antagonists; Humans; Hydroxyzine; Immunosuppression Therapy; Pollen; Promethazine; Skin Tests; Tripelennamine; Yeasts | 1973 |
Outpatient management of acute urticaria: the role of prednisone.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Analysis of Variance; Anti-Inflammatory Agents; Antipruritics; Diphenhydramine; Double-Blind Method; Drug Therapy, Combination; Emergency Service, Hospital; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Middle Aged; Prednisone; Prospective Studies; Urticaria | 1995 |
Adverse central nervous system effects of older antihistamines in children.
Topics: Child; Cross-Over Studies; Diphenhydramine; Double-Blind Method; Event-Related Potentials, P300; Fatigue; Female; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Rhinitis; Skin; Skin Tests | 1996 |
35 other study(ies) available for hydroxyzine and diphenhydramine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Molecular properties and pharmacokinetic behavior of cetirizine, a zwitterionic H1-receptor antagonist.
Topics: Alkanes; Animals; Biological Transport; Blood Proteins; Brain; Cetirizine; Histamine H1 Antagonists; Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydroxyzine; Isomerism; Models, Molecular; Molecular Conformation; Octanols; Rats; Water | 1998 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Treatment of cold urticaria.
Topics: Adult; Cimetidine; Cold Temperature; Cyproheptadine; Diphenhydramine; Drug Therapy, Combination; Humans; Hydroxyzine; Male; Terbutaline; Urticaria | 1979 |
The effects of vadocaine, dextromethorphan, diphenhydramine and hydroxyzine on the ciliary beat frequency in rats in vitro.
Topics: Animals; Cilia; Dextromethorphan; Diphenhydramine; Hydroxyzine; Male; Mucociliary Clearance; Piperidines; Rats; Rats, Inbred Strains; Time Factors; Trachea | 1990 |
Anxiety treatment.
Topics: Anxiety Disorders; Diphenhydramine; Humans; Hydroxyzine | 1990 |
Significant envenomation from a preserved rattlesnake head (in a patient with a history of immediate hypersensitivity to antivenin).
Topics: Administration, Oral; Adult; Animals; Antivenins; Crotalid Venoms; Diphenhydramine; Epinephrine; Humans; Hydroxyzine; Hypersensitivity, Immediate; Injections, Intravenous; Injections, Subcutaneous; Male; Prednisone; Serum Sickness; Snakes | 1986 |
Effect of drugs on after-nystagmus induced by lateral vestibular nucleus stimulation.
Topics: Animals; Cats; Chlorpromazine; Cyclizine; Dimenhydrinate; Diphenhydramine; Electric Stimulation; Hydroxyzine; Lidocaine; Meclizine; Nystagmus, Pathologic; Pentobarbital; Phenothiazines; Piperazines; Prochlorperazine; Promethazine; Tripelennamine; Vestibular Nuclei | 1967 |
The effect of diphenyl-piperazine compounds and other agents on diphenylhydantoin, zoxazolamine and hexobarbital metabolism.
Topics: Animals; Benzopyrenes; Cyclizine; DDT; Diphenhydramine; Endoplasmic Reticulum; Hexobarbital; Humans; Hydroxyzine; Liver; Male; Meclizine; Methylcholanthrene; Mice; Microscopy, Electron; Phenethylamines; Phenobarbital; Phenytoin; Piperazines; Trifluoperazine; Zoxazolamine | 1968 |
Drug-induced and naturally occurring myeloid bodies.
Topics: Amino Alcohols; Aminoglutethimide; Animals; Anticholesteremic Agents; Benzyl Compounds; Biphenyl Compounds; Chloroquine; Clofibrate; Cyclizine; Diphenhydramine; Endoplasmic Reticulum; Ethers; Haloperidol; Histamine H1 Antagonists; Hydroxyzine; Imidazoles; Inclusion Bodies; Kidney; Liver; Lysosomes; Male; Meclizine; Mice; Microscopy, Electron; Piperazines; Pyrrolidines; Rats; Triparanol; Trophoblasts | 1972 |
Sedation of young children for electric response audiometry (ERA). Summary of a symposium.
Topics: Age Factors; Anesthesia, Inhalation; Audiometry; Barbiturates; Cerebral Cortex; Child; Child, Preschool; Chloral Hydrate; Chlorpromazine; Congresses as Topic; Diazepam; Diphenhydramine; Evoked Potentials; Haloperidol; Halothane; Humans; Hydroxybutyrates; Hydroxyzine; Hypnotics and Sedatives; Infant; Ketamine; Methaqualone; Nitrous Oxide; Promazine; Promethazine; Sleep | 1973 |
Type and prevalence of medication used in the treatment of hyperactive children.
Topics: Child; Child Behavior Disorders; Chlorpromazine; Dextroamphetamine; Diphenhydramine; Education, Special; Humans; Hydroxyzine; Hyperkinesis; Income; Maryland; Methylphenidate; School Nursing; Socioeconomic Factors; Statistics as Topic; Surveys and Questionnaires; Thioridazine | 1974 |
Premedication in dentistry.
Topics: Chloral Hydrate; Diphenhydramine; Hydroxyzine; Meperidine; Meprobamate; Preanesthetic Medication; Promethazine; Secobarbital | 1970 |
Analgesic profile of tranquillizers in multiple screening tests in mice.
Topics: Acetaminophen; Aminopyrine; Analgesics; Animals; Aspirin; Chlorpromazine; Codeine; Diazepam; Diphenhydramine; Electric Stimulation; Haloperidol; Hot Temperature; Hydroxyzine; Imipramine; Isocarboxazid; Male; Meprobamate; Mice; Morphine; Perphenazine; Phenobarbital; Phenothiazines; Promazine; Promethazine; Reserpine; Tetrabenazine; Thiopental; Time Factors; Tranquilizing Agents | 1968 |
Method for cataract extraction in Parkinsonism.
Topics: Cataract Extraction; Diphenhydramine; Humans; Hydroxyzine; Male; Middle Aged; Parkinson Disease | 1965 |
Histamine release and therapy of severe dermatographism.
Topics: Adolescent; Animals; Cyproheptadine; Diphenhydramine; Female; Histamine; Histamine Release; Humans; Hydroxyzine; Immunization, Passive; Pruritus; Rats; Urticaria | 1981 |
Radiographic contrast media-induced noncardiogenic pulmonary edema: case report and review of the literature.
Topics: Cardiac Catheterization; Contrast Media; Diphenhydramine; Furosemide; Humans; Hydroxyzine; Male; Methylprednisolone; Middle Aged; Positive-Pressure Respiration; Prednisone; Pulmonary Edema | 1984 |
Life-threatening idiopathic anaphylaxis associated with hyperimmunoglobulinemia E.
Topics: Anaphylaxis; Cimetidine; Coronary Disease; Diphenhydramine; Humans; Hydroxyzine; Hypergammaglobulinemia; Hypotension, Orthostatic; Immunoglobulin E; Intestinal Obstruction; Intestine, Small; Male; Middle Aged; Prednisone; Urticaria | 1984 |
Dermatologic cross-sensitivity between diltiazem and amlodipine.
Topics: Amlodipine; Diltiazem; Diphenhydramine; Drug Eruptions; Humans; Hydroxyzine; Male; Methylprednisolone; Middle Aged; Pruritus | 1994 |
Suspected vein irritation from i.v. pentamidine isethionate.
Topics: Adult; Anti-Allergic Agents; Antifungal Agents; Antipruritics; Diphenhydramine; Drug Eruptions; Female; Humans; Hydroxyzine; Pentamidine | 1996 |
Cardiotoxic potential and CNS effects of first-generation antihistamines.
Topics: Animals; Central Nervous System; Diphenhydramine; Electrophysiology; Heart; Histamine H1 Antagonists; Humans; Hydroxyzine; Potassium Channel Blockers; Potassium Channels; Receptors, Histamine H1; Structure-Activity Relationship | 2000 |
Titrimetric and spectrophotometric assay of some antihistamines through the determination of the chloride of their hydrochlorides.
Topics: Cetirizine; Chemistry, Pharmaceutical; Chlorides; Diphenhydramine; Histamine H1 Antagonists; Hydroxyzine; Spectrophotometry; Tablets; Titrimetry | 2002 |
Antihistamines in the management of canine atopic dermatitis: a retrospective study of 171 dogs (1992-1998).
Topics: Allergens; Animals; Chlorpheniramine; Clemastine; Dermatitis, Atopic; Diphenhydramine; Dog Diseases; Dogs; Female; Histamine H1 Antagonists; Hydroxyzine; Male; Records; Retrospective Studies; Treatment Outcome | 2002 |
Neuropharmacological comparison of atropine, scopolamine, banactyzine, diphenhydramine and hydroxyzine.
Topics: Atropine; Behavior; Diphenhydramine; Electroencephalography; Humans; Hydroxyzine; Neuropharmacology; Parasympatholytics; Scopolamine | 1960 |
ARTERIAL CARBON DIOXIDE AND OXYGEN TENSIONS DURING SPINAL BLOCK.
Topics: Anesthesia, Conduction; Anesthesia, Obstetrical; Anesthesia, Spinal; Blood Gas Analysis; Carbon Dioxide; Cesarean Section; Diphenhydramine; Drug Therapy; Female; Gangrene; Geriatrics; Halothane; Heart Diseases; Humans; Hydroxyzine; Levallorphan; Lidocaine; Lung Diseases; Metaraminol; Methoxamine; Obesity; Oxygen; Oxygen Inhalation Therapy; Pregnancy; Respiration; Surgical Procedures, Operative | 1965 |
Effects of calcineurin inhibitors on an in vitro assay for chronic urticaria.
Topics: Basophils; Calcineurin Inhibitors; Cells, Cultured; Chronic Disease; Complement C5a; Cyclosporine; Diphenhydramine; Dose-Response Relationship, Immunologic; Histamine H1 Antagonists; Histamine Release; Humans; Hydroxyzine; Immunoglobulin G; Immunosuppressive Agents; Leukocytes; Methotrexate; Recurrence; Tacrolimus; Urticaria | 2005 |
Moderate sedation for echocardiography of preschoolers.
Topics: Anesthesia, General; Child, Preschool; Chloral Hydrate; Conscious Sedation; Cost-Benefit Analysis; Diphenhydramine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Echocardiography; Female; Humans; Hydroxyzine; Hypnotics and Sedatives; Male; Midazolam; Retrospective Studies | 2010 |
Are antimuscarinic effects common in hydroxyzine overdose? A cohort analysis of antimuscarinic effects in hydroxyzine and diphenhydramine-poisoned patients.
Topics: Child; Cohort Studies; Diphenhydramine; Humans; Hydroxyzine; Muscarinic Antagonists; Poison Control Centers; Poisons; United States | 2023 |
Comment on: Are antimuscarinic effects common in hydroxyzine overdose? A cohort analysis of antimuscarinic effects in hydroxyzine and diphenhydramine poisoned patient.
Topics: Cohort Studies; Diphenhydramine; Histamine H1 Antagonists; Humans; Hydroxyzine; Muscarinic Antagonists | 2023 |