hydroxyzine and cimetidine

hydroxyzine has been researched along with cimetidine in 39 studies

Research

Studies (39)

Timeframe	Studies, this research(%)	All Research%
pre-1990	19 (48.72)	18.7374
1990's	7 (17.95)	18.2507
2000's	4 (10.26)	29.6817
2010's	9 (23.08)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Bakker, RA; Leurs, R; Lim, HD; Ling, P; Thurmond, RL; van Rijn, RM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Highet, AS; Titterington, DM	1
Bajorin, DF; Chapman, PB; Cody, BV; Cordon-Cardo, C; Dantes, L; Houghton, AN; Oettgen, HF; Scheinberg, D; Templeton, MA; Wong, GY	1
Balster, RL; Beardsley, PM	1
Bent, S; Braam, U; Fehling, U; Schmutzler, W; Schunack, W	1
Eliakim, R; Karmeli, F; Okon, E; Rachmilewitz, D	1
Kauppinen, K; Männistö, PT; Salo, OP	1
Katz, RM; Mickey, MR; Quaranta, JH; Rachelefsky, GS; Rohr, AS; Siegel, SC; Spector, SL	1
Sutton, JC	1
Youngchaiyud, U	1
Bogdanovic, RP; Brandes, LJ	1
Deutsch, PH	1
Simon, RA	1
Harvey, RP; Schocket, AL	1
Cohen, SH; Kalbfleisch, J; Monroe, EW; Schulz, CI	1
Harvey, RP; Schocket, AL; Wegs, J	1
Kaliner, M; Ottesen, EA; Shelhamer, JH	1
Baker, JP	1
Kaplan, AP	1
Cupa, M; Fournier, JL; Khenifer, L; Le Mapihan, Y; Pierrot, M	1
Greenberger, PA	1
Berman, BA; Ross, RN; Sly, RM	1
Kaliner, M; Shelhamer, JH; Sigler, R; Summers, R	1
Simons, FE; Simons, KJ; Sussman, GL	1
Chen, X; Simons, FE; Simons, KJ	1
Bourget, P; Cattaneo, I; Edouard, D; Narchi, P; Otz, J	1
Chai, JY; Guk, SM; Hong, SJ; Kim, TH; Park, JH; Shin, EH	1
Sea, J; Teichman, JM	1
Dancel, R; Handler, L; Mounsey, A	1
Giusto, LL; Shoskes, DA; Zahner, PM	1

Reviews

3 review(s) available for hydroxyzine and cimetidine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Paediatric painful bladder syndrome/interstitial cystitis: diagnosis and treatment. Drugs, 2009, Volume: 69, Issue:3 Topics: Administration, Intravesical; Amitriptyline; Child; Cimetidine; Cystitis, Interstitial; Diet Therapy; Dimethyl Sulfoxide; Humans; Hydroxyzine; Life Style; Pain; Pentosan Sulfuric Polyester	2009
An evaluation of the pharmacotherapy for interstitial cystitis. Expert opinion on pharmacotherapy, 2018, Volume: 19, Issue:10 Topics: Amitriptyline; Antibodies, Monoclonal; Antidepressive Agents, Tricyclic; Cimetidine; Cystitis, Interstitial; Histamine Antagonists; Humans; Hydroxyzine; Immunosuppressive Agents; Pentosan Sulfuric Polyester	2018

Trials

7 trial(s) available for hydroxyzine and cimetidine

Article	Year
Comparison of the efficacy of four antihistamines in chronic urticaria. Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1988, Volume: 71, Issue:10 Topics: Adolescent; Adult; Chlorpheniramine; Chronic Disease; Cimetidine; Clemastine; Double-Blind Method; Drug Combinations; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Middle Aged; Pruritus; Random Allocation; Urticaria	1988
The effect of H1 and H2 blockade on cutaneous histamine response in man. The Journal of allergy and clinical immunology, 1980, Volume: 65, Issue:2 Topics: Cimetidine; Dose-Response Relationship, Immunologic; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Hydroxyzine; Skin Tests; Urticaria	1980
Combined H1 and H2 antihistamine therapy in chronic urticaria. Archives of dermatology, 1981, Volume: 117, Issue:7 Topics: Adult; Aged; Chronic Disease; Cimetidine; Double-Blind Method; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Guanidines; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Hydroxyzine; Male; Middle Aged; Urticaria	1981
A controlled trial of therapy in chronic urticaria. The Journal of allergy and clinical immunology, 1981, Volume: 68, Issue:4 Topics: Adult; Chlorpheniramine; Chronic Disease; Cimetidine; Clinical Trials as Topic; Cyproheptadine; Drug Therapy, Combination; Female; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Middle Aged; p-Methoxy-N-methylphenethylamine; Terbutaline; Urticaria	1981
Effects of infused histamine: analysis of the effects of H-1 and H-2 histamine receptor antagonists on cardiovascular and pulmonary responses. The Journal of allergy and clinical immunology, 1981, Volume: 68, Issue:5 Topics: Adult; Blood Pressure; Cardiovascular System; Cimetidine; Female; Guanidines; Histamine; Humans; Hydroxyzine; Male; Peak Expiratory Flow Rate; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Respiratory Function Tests; Skin Physiological Phenomena; Temperature	1981
Effect of the H2-antagonist cimetidine on the pharmacokinetics and pharmacodynamics of the H1-antagonists hydroxyzine and cetirizine in patients with chronic urticaria. The Journal of allergy and clinical immunology, 1995, Volume: 95, Issue:3 Topics: Adolescent; Adult; Aged; Cetirizine; Chronic Disease; Cimetidine; Double-Blind Method; Drug Combinations; Drug Interactions; Female; Humans; Hydroxyzine; Male; Middle Aged; Skin Tests; Urticaria	1995
Gastric fluid pH and volume in gynaecologic out-patients. Influences of cimetidine and cimetidine-sodium citrate combination. European journal of anaesthesiology, 1993, Volume: 10, Issue:5 Topics: Adult; Anesthesia, General; Anti-Ulcer Agents; Cimetidine; Citrates; Female; Gastric Acid; Gastric Mucosa; Gynecologic Surgical Procedures; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Hydrogen-Ion Concentration; Hydroxyzine; Laparoscopy; Prospective Studies; Sodium Citrate; Stomach	1993

Other Studies

29 other study(ies) available for hydroxyzine and cimetidine

Article	Year
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist. The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:3 Topics: Cell Line; Histamine Agonists; Humans; Imidazoles; Indoles; Isothiuronium; Ligands; Methylhistamines; Piperazines; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Receptors, Histamine H4	2005
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Treatment of cold urticaria. The British journal of dermatology, 1979, Volume: 101, Issue:1 Topics: Adult; Cimetidine; Cold Temperature; Cyproheptadine; Diphenhydramine; Drug Therapy, Combination; Humans; Hydroxyzine; Male; Terbutaline; Urticaria	1979
Treatment with high dose mouse monoclonal (anti-GD3) antibody R24 in patients with metastatic melanoma. Melanoma research, 1992, Volume: 2, Issue:5-6 Topics: Adult; Animals; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; Antigens, CD; Cimetidine; Complement System Proteins; Female; Gangliosides; Humans; Hydroxyzine; Immunoglobulin G; Lymphocyte Depletion; Male; Melanoma; Mice; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; T-Lymphocytes; Urticaria	1992
The intravenous self-administration of antihistamines by rhesus monkeys. Drug and alcohol dependence, 1992, Volume: 30, Issue:2 Topics: Animals; Benzhydryl Compounds; Chlorpheniramine; Cimetidine; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Hydroxyzine; Macaca mulatta; Male; Motivation; Pyrilamine; Self Administration; Substance-Related Disorders; Tripelennamine	1992
The influence of H1-, H2- and H3-receptors on the spontaneous and ConA induced histamine release from human adenoidal mast cells. Agents and actions, 1991, Volume: 33, Issue:1-2 Topics: Adenoids; Cimetidine; Concanavalin A; Guanidines; Histamine Antagonists; Humans; Hydroxyzine; Imidazoles; Impromidine; Mast Cells; Meclizine; Methylhistamines; Piperidines; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3	1991
Gastric mucosal damage by ethanol is mediated by substance P and prevented by ketotifen, a mast cell stabilizer. Gastroenterology, 1991, Volume: 100, Issue:5 Pt 1 Topics: Animals; Azepines; Cimetidine; Ethanol; Gastric Acid; Gastric Mucosa; Gastrins; Hydroxyzine; In Vitro Techniques; Ketotifen; Leukotriene B4; Male; Mast Cells; Pepsin A; Peptide Fragments; Platelet Activating Factor; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; SRS-A; Substance P; Triazoles	1991
Cimetidine increases the plasma concentration of hydroxyzine. Acta dermato-venereologica, 1986, Volume: 66, Issue:4 Topics: Chronic Disease; Cimetidine; Drug Interactions; Drug Therapy, Combination; Humans; Hydroxyzine; Urticaria	1986
The natural history and response to therapy of chronic urticaria and angioedema. Annals of allergy, 1989, Volume: 62, Issue:5 Topics: Adrenal Cortex Hormones; Adult; Angioedema; Chronic Disease; Cimetidine; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Skin Tests; Urticaria	1989
Repeat chemonucleolysis. Clinical orthopaedics and related research, 1986, Issue:206 Topics: Adolescent; Adult; Anaphylaxis; Chymopapain; Cimetidine; Female; Follow-Up Studies; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Hydroxyzine; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Premedication; Recurrence; Risk; Time Factors	1986
New evidence that the antiestrogen binding site may be a novel growth-promoting histamine receptor (?H3) which mediates the antiestrogenic and antiproliferative effects of tamoxifen. Biochemical and biophysical research communications, 1986, Jan-29, Volume: 134, Issue:2 Topics: Animals; Binding, Competitive; Biological Assay; Cimetidine; Female; Hydroxyzine; Microsomes, Liver; Ovariectomy; Phosphatidylethanolamines; Pyrilamine; Rats; Receptors, Estrogen; Receptors, Histamine; Structure-Activity Relationship; Tamoxifen; Uterus	1986
Dermatographism treated with hydroxyzine and cimetidine and ranitidine. Annals of internal medicine, 1984, Volume: 101, Issue:4 Topics: Adult; Cimetidine; Dermatitis, Atopic; Drug Therapy, Combination; Humans; Hydroxyzine; Male; Pruritus; Ranitidine	1984
Treatment of systemic mastocytosis. The New England journal of medicine, 1980, Jan-24, Volume: 302, Issue:4 Topics: Cimetidine; Cromolyn Sodium; Cyproheptadine; Drug Therapy, Combination; Guanidines; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Middle Aged; Urticaria Pigmentosa	1980
Effects of infused histamine: correlation of plasma histamine levels and symptoms. The Journal of allergy and clinical immunology, 1982, Volume: 69, Issue:3 Topics: Adult; Blood Pressure; Cimetidine; Female; Headache; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Hydroxyzine; Infusions, Parenteral; Male; Pulse; Skin	1982
A new series of oral medications for chronic (cancer) pain relief. Comprehensive therapy, 1984, Volume: 10, Issue:5 Topics: Administration, Oral; Aluminum Hydroxide; Analgesics, Opioid; Antacids; Antiemetics; Cimetidine; Cocaine; Drug Administration Schedule; Drug Combinations; Humans; Hydroxyzine; Long-Term Care; Morphine; Nausea; Neoplasms; Pain; Vomiting	1984
Exercise-induced hives. The Journal of allergy and clinical immunology, 1984, Volume: 73, Issue:5 Pt 2 Topics: Cimetidine; Cold Temperature; Cyproheptadine; Histamine; Humans; Hydroxyzine; Hypotension; Methacholine Chloride; Methacholine Compounds; Physical Exertion; Skin Temperature; Tripelennamine; Urticaria	1984
A specific antihistaminic premedication anti H1 anti H2 for pediatric anesthesia. Acta anaesthesiologica Belgica, 1984, Volume: 35 Suppl Topics: Anaphylaxis; Anesthesia, General; Child; Child, Preschool; Cimetidine; Drug Therapy, Combination; Female; Humans; Hydroxyzine; Male; Preanesthetic Medication; Time Factors	1984
Life-threatening idiopathic anaphylaxis associated with hyperimmunoglobulinemia E. The American journal of medicine, 1984, Volume: 76, Issue:3 Topics: Anaphylaxis; Cimetidine; Coronary Disease; Diphenhydramine; Humans; Hydroxyzine; Hypergammaglobulinemia; Hypotension, Orthostatic; Immunoglobulin E; Intestinal Obstruction; Intestine, Small; Male; Middle Aged; Prednisone; Urticaria	1984
Urticaria. Cutis, 1982, Volume: 30, Issue:6 Topics: Allergens; Cimetidine; Cyproheptadine; Humans; Hydroxyzine; Urticaria	1982
Effect of the H2-receptor antagonist cimetidine, on the pharmacokinetics and pharmacodynamics of the H1-receptor antagonists hydroxyzine and cetirizine in rabbits. Pharmaceutical research, 1994, Volume: 11, Issue:2 Topics: Alanine Transaminase; Analysis of Variance; Animals; Aspartate Aminotransferases; Cetirizine; Chromatography, High Pressure Liquid; Cimetidine; Drug Synergism; Half-Life; Hydroxyzine; Hypersensitivity, Immediate; Injections, Intravenous; L-Lactate Dehydrogenase; Liver; Rabbits	1994
Effects of anti-allergic drugs on intestinal mastocytosis and worm expulsion of rats infected with Neodiplostomum seoulense. The Korean journal of parasitology, 2003, Volume: 41, Issue:2 Topics: Animals; Cimetidine; Cyclosporine; Histamine H1 Antagonists; Histamine H2 Antagonists; Hydroxyzine; Immunosuppressive Agents; Intestinal Diseases, Parasitic; Mastocytosis; Prednisolone; Rats; Rats, Sprague-Dawley; Trematoda; Trematode Infections	2003
Medications for treatment of interstitial cystitis. American family physician, 2015, Jan-15, Volume: 91, Issue:2 Topics: Adult; Amitriptyline; Cimetidine; Cystitis, Interstitial; Evidence-Based Medicine; Female; Humans; Hydroxyzine; Male; Middle Aged	2015