hydroxyzine and caffeine

hydroxyzine has been researched along with caffeine in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19906 (40.00)18.7374
1990's0 (0.00)18.2507
2000's3 (20.00)29.6817
2010's6 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Ahman, M; Holmén, AG; Wan, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Glen, RC; Lowe, R; Mitchell, JB1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
León Díaz, C1
Borges, J; Zavaleta, C1
Senault, B1
Dikstein, S; Grotto, M; Sulman, FG1
Cirelli, C; Greenspan, RJ; Shaw, PJ; Tononi, G1
FORNEY, RB; HUGHES, FW; KHAN, AU1

Reviews

1 review(s) available for hydroxyzine and caffeine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for hydroxyzine and caffeine

ArticleYear
[Evaluation of a new analgesic combination in the control of pain in different odontological processes].
    Anales espanoles de odontoestomatologia, 1976, Volume: 35, Issue:5

    Topics: Acetaminophen; Adolescent; Adult; Analgesics; Caffeine; Clinical Trials as Topic; Dextropropoxyphene; Drug Combinations; Drug Evaluation; Female; Humans; Hydroxyzine; Male; Middle Aged; Tablets; Toothache

1976
Study of a new analgesic compound in the treatment of tension headache.
    The Journal of international medical research, 1976, Volume: 4, Issue:1

    Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Caffeine; Clinical Trials as Topic; Dextropropoxyphene; Drug Combinations; Drug Evaluation; Female; Headache; Humans; Hydroxyzine; Male; Middle Aged

1976

Other Studies

12 other study(ies) available for hydroxyzine and caffeine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
[Intraspecific aggressive behavior induced by apomorphine in the rat].
    Psychopharmacologia, 1970, Volume: 18, Issue:3

    Topics: Acepromazine; Age Factors; Aggression; Amitriptyline; Animals; Apomorphine; Atropine; Behavior, Animal; Caffeine; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Diazepam; Drug Antagonism; Electroshock; Environment; Haloperidol; Humans; Hydroxyzine; Imipramine; Male; Meprobamate; Morphine; Rats; Reserpine; Sex Factors; Sound; Species Specificity; Thiazines; Thioridazine

1970
Additive and augmentative synergism between analgesic drugs.
    Archives internationales de pharmacodynamie et de therapie, 1965, Volume: 155, Issue:2

    Topics: Acetaminophen; Analgesics; Animals; Aspirin; Caffeine; Codeine; Dextropropoxyphene; Drug Synergism; Hydroxyzine; Meprobamate; Mice; Phenacetin

1965
Correlates of sleep and waking in Drosophila melanogaster.
    Science (New York, N.Y.), 2000, Mar-10, Volume: 287, Issue:5459

    Topics: Animals; Arylamine N-Acetyltransferase; Behavior, Animal; Biogenic Monoamines; Caffeine; Carrier Proteins; Circadian Rhythm; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Drosophila melanogaster; Drosophila Proteins; Fatty Acid Synthases; Female; Gene Dosage; Gene Expression Profiling; Genes, Insect; Homeostasis; HSC70 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Hydroxyzine; Mutation; Rest; Sleep; Transcription, Genetic; Wakefulness

2000
PLASMA FREE FATTY ACIDS IN RATS AFTER SHOCK AS MODIFIED BY CENTRALLY ACTIVE DRUGS.
    Archives internationales de pharmacodynamie et de therapie, 1964, Oct-01, Volume: 151

    Topics: Amphetamine; Amphetamines; Blood; Caffeine; Chlordiazepoxide; Chlorpromazine; Electroshock; Ethanol; Fatty Acids; Fatty Acids, Nonesterified; Hydroxyzine; Meprobamate; Pentobarbital; Pharmacology; Rats; Research; Reserpine; Stress, Physiological; Tranquilizing Agents

1964