hydroxyzine and buspirone

hydroxyzine has been researched along with buspirone in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.00)18.7374
1990's3 (12.00)18.2507
2000's11 (44.00)29.6817
2010's10 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bergström, F; Giordanetto, F; Rehngren, M; Tunek, A; Wan, H1
Ahman, M; Holmén, AG; Wan, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Glen, RC; Lowe, R; Mitchell, JB1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Healy, B1
Bartel, PR; Becker, PJ; Blom, MW; Sommers, DK; Van der Meyden, CH1
Lader, M; Scotto, JC1
Davidson, JR1
Gale, C; Oakley-Browne, M4
Goodman, WK1
Barbui, C; Cipriani, A; Guaiana, G1
Gale, CK; Millichamp, J1

Reviews

9 review(s) available for hydroxyzine and buspirone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Pharmacotherapy of generalized anxiety disorder.
    The Journal of clinical psychiatry, 2001, Volume: 62 Suppl 11

    Topics: Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, Tricyclic; Anxiety Disorders; Benzodiazepines; Buspirone; Comorbidity; Depressive Disorder; Heart Rate; Humans; Hydroxyzine; Serotonin Receptor Agonists; Treatment Outcome

2001
Generalised anxiety disorder.
    Clinical evidence, 2003, Issue:9

    Topics: Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; Benzodiazepines; Buspirone; Carbolines; Cognitive Behavioral Therapy; Humans; Hydroxyzine

2003
Selecting pharmacotherapy for generalized anxiety disorder.
    The Journal of clinical psychiatry, 2004, Volume: 65 Suppl 13

    Topics: Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Buspirone; Histamine H1 Antagonists; Humans; Hydroxyzine; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

2004
Generalised anxiety disorder.
    Clinical evidence, 2004, Issue:11

    Topics: Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; Benzodiazepines; Buspirone; Carbolines; Cognitive Behavioral Therapy; Humans; Hydroxyzine; Kava; Phytotherapy

2004
Generalised anxiety disorder.
    Clinical evidence, 2004, Issue:12

    Topics: Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; Benzodiazepines; Buspirone; Cognitive Behavioral Therapy; Humans; Hydroxyzine; Kava; Phytotherapy

2004
Generalised anxiety disorder.
    Clinical evidence, 2005, Issue:14

    Topics: Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; Benzodiazepines; Buspirone; Carbolines; Cognitive Behavioral Therapy; Humans; Hydroxyzine

2005
Hydroxyzine for generalised anxiety disorder.
    The Cochrane database of systematic reviews, 2010, Dec-08, Issue:12

    Topics: Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; Benzodiazepines; Buspirone; Chlordiazepoxide; Humans; Hydroxyzine; Randomized Controlled Trials as Topic

2010
Generalised anxiety disorder.
    BMJ clinical evidence, 2011, Oct-27, Volume: 2011

    Topics: Anxiety Disorders; Benzodiazepines; Buspirone; Humans; Hydroxyzine; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Sertraline

2011

Trials

2 trial(s) available for hydroxyzine and buspirone

ArticleYear
The comparison of the effects of multi and single doses of buspirone, chlordiazepoxide and hydroxyzine on psychomotor function and EEG.
    Fundamental & clinical pharmacology, 1992, Volume: 6, Issue:1

    Topics: Adult; Buspirone; Chlordiazepoxide; Drug Administration Schedule; Electroencephalography; Humans; Hydroxyzine; Male; Psychomotor Performance

1992
A multicentre double-blind comparison of hydroxyzine, buspirone and placebo in patients with generalized anxiety disorder.
    Psychopharmacology, 1998, Volume: 139, Issue:4

    Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety Disorders; Buspirone; Depression; Double-Blind Method; Female; Humans; Hydroxyzine; Male; Middle Aged; Treatment Outcome

1998

Other Studies

14 other study(ies) available for hydroxyzine and buspirone

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
High-throughput screening of drug-brain tissue binding and in silico prediction for assessment of central nervous system drug delivery.
    Journal of medicinal chemistry, 2007, Sep-20, Volume: 50, Issue:19

    Topics: Animals; Brain; Central Nervous System Agents; Dialysis; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Mice; Models, Statistical; Protein Binding; Quantitative Structure-Activity Relationship; Rats

2007
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Nurses talk about their experiences with drug addiction.
    RN, 1992, Volume: 55, Issue:7

    Topics: Benzodiazepines; Buspirone; Female; Humans; Hydroxyzine; Nurses; Professional Impairment; Pruritus; Substance-Related Disorders; Vaginal Diseases

1992