hydroxyurea and zidovudine

hydroxyurea has been researched along with zidovudine in 56 studies

Research

Studies (56)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (1.79)	18.7374
1990's	23 (41.07)	18.2507
2000's	20 (35.71)	29.6817
2010's	10 (17.86)	24.3611
2020's	2 (3.57)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Lombardo, F; Obach, RS; Waters, NJ	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Clement, B; Indorf, P; Kubitza, C; Kunze, T; Scheidig, AJ	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Eckstein, F; Karlsson, A; Reichard, P	1
Chokekuchai, S; Gao, WY; Johns, DG; Mitsuya, H	1
Gao, WY; Johns, DG; Mitsuya, H	1
Grange, JM; Hamedi-Sangsari, F; Malley, SD; Vila, JR	1
Cara, A; Gallo, RC; Lisziewicz, J; Lori, F; Malykh, A; Sun, D; Weinstein, JN	1
Auclair, C; Carteau, S; Goulaouic, H; Mouscadet, JF; Subra, F	1
Darnowski, JW; Ottaviani, E; Tosi, P; Tura, S; Visani, G	1
Bianchi, V; Borella, S; Calderazzo, F; Chieco Bianchi, L; Ferraro, P; Reichard, P	1
Bianchi, LC; Bianchi, V; Borella, S; Calderazzo, F; D'Agaro, P; Giacca, M; Rampazzo, C; Reichard, P	1
Giacchino, R; Lori, F; Maserati, R; Regazzi, MB; Villani, P	1
Cox, S; Palmer, S	1
Comar, M; De Paoli, P; Giacca, M; Simonelli, C; Tirelli, U; Zanussi, S	1
Chiang, Y; Drake, RR; Govindarajan, R; Hume, SD; Krisa, S; McMasters, R; Munshi, NC; Rechtin, TM; Saylors, RL	1
Gao, WY; Johns, DG	1
Foli, A; Gallo, RC; Lisziewicz, J; Lori, F; Maserati, R; Minoli, L; Wainberg, MA	1
Julias, JG; Pathak, VK	1
Back, DJ; Barry, MG; Henry-Mowatt, JS; Hoggard, PG; Kewn, S; Sales, SD; Veal, GJ	1
Boucher, CA; De Vos, NM; Nottet, HS; Orendi, JM; Snippe, H; Verhoef, J; Visser, MR	1
Alexander, CS; Harrigan, PR; Mo, T; Montaner, JS; Raboud, JM; Rae, S; Rouleau, D; Zala, C	1
Davis, C; Heredia, A; Redfield, R	1
Busch, M; Hecht, FM; Kahn, J; Levy, JA; Martinez-Marino, B; Ong, JC; Stranford, SA	1
Mendelow, BV; Sanne, I; Smego, RA	1
Chaisson, RE; Keruly, JC; Moore, RD	1
Foli, A; Lisziewicz, J; Lori, F; Maserati, R; Minoli, L; Tinelli, C	1
Mascolini, M	1
Falkenberg, J; Gilden, D; Torres, G	1
Hanna, L	1
Torres, G	1
Boelaert, JR; Piette, J; Sperber, K	1
Adams, EM; Bennett, K; Collier, AC; Gilbert, PB; Goodwin, D; Havlir, DV; Hirsch, MS; Holohan, MK; Richman, DD; Schnittman, S; Tebas, P; Wheat, LJ	1
Bisset, LR; Böni, J; Hofmann-Lehmann, R; Lüthy, R; Lutz, H; Schüpbach, J	1
Flexner, C; Gandhi, R	1
Gajary, LC; Mansky, LM; Pearl, DK	1
Almond, LM; Back, DJ; De Vries, C; Gould, J; Hoggard, PG; Kewn, S; Khoo, SH; Lou, Y; Maherbe, A; Sales, SD; Wood, R	1
Andron, L; Asmuth, DM; Grady, JJ; Green, S; McKinsey, DS; Pollard, RB; Rossero, R	1
Barber, GN; Cabral, L; Dittmer, DP; Ghosh, SK; Harrington, WJ; Kurokawa, M; Mian, AM; Ramos, JC; Toomey, NL; Whitby, D	1
Lovett, ST; Sutera, VA	1
Jin, Y; Li, M; Qi, S; Yao, W; Zhang, S; Zhao, J	1
Assaraf, YG; Berman, B; Levin, M; Stark, M	1

Reviews

3 review(s) available for hydroxyurea and zidovudine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Selective depletion of DNA precursors: an evolving strategy for potentiation of dideoxynucleoside activity against human immunodeficiency virus. Biochemical pharmacology, 1998, May-15, Volume: 55, Issue:10 Topics: Anti-HIV Agents; Clinical Trials as Topic; Dideoxynucleosides; Drug Synergism; Drug Therapy, Combination; Enzyme Inhibitors; HIV-1; Humans; Hydroxyurea; Ribonucleotide Reductases; Zidovudine	1998
Systematic review of combination antiretroviral therapy with didanosine plus hydroxyurea: a partial solution to Africa's HIV/AIDS problem? International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2001, Volume: 5, Issue:1 Topics: Africa; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Hydroxyurea; MEDLINE; Treatment Outcome; Viral Load; Zidovudine	2001

Trials

7 trial(s) available for hydroxyurea and zidovudine

Article	Year
Pharmacokinetics of hydroxyurea in patients infected with human immunodeficiency virus type I. Journal of clinical pharmacology, 1996, Volume: 36, Issue:2 Topics: Adult; Antiviral Agents; Dose-Response Relationship, Drug; Drug Therapy, Combination; Evaluation Studies as Topic; Female; HIV Infections; HIV-1; Humans; Hydroxyurea; Male; Prospective Studies; Zidovudine	1996
No therapeutic advantage from didanosine (ddI) and hydroxyurea versus ddI alone in patients with HIV infection. AIDS (London, England), 1997, Volume: 11, Issue:10 Topics: CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Hydroxyurea; RNA, Viral; Treatment Outcome; Viremia; Zidovudine	1997
Human immunodeficiency virus-infected persons with mutations conferring resistance to zidovudine show reduced virologic responses to hydroxyurea and stavudine-lamivudine. The Journal of infectious diseases, 2000, Volume: 181, Issue:2 Topics: Anti-HIV Agents; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Hydroxyurea; Lamivudine; Logistic Models; Mutation; Nucleic Acid Synthesis Inhibitors; Reverse Transcriptase Inhibitors; Stavudine; Viral Load; Zidovudine	2000
Hydroxyurea and didanosine is a more potent combination than hydroxyurea and zidovudine. Antiviral therapy, 1997, Volume: 2, Issue:1 Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Female; HIV Infections; Humans; Hydroxyurea; Male; Middle Aged; Zidovudine	1997
Effects of treatment intensification with hydroxyurea in HIV-infected patients with virologic suppression. AIDS (London, England), 2001, Jul-27, Volume: 15, Issue:11 Topics: Adolescent; Adult; Anti-HIV Agents; Case-Control Studies; CD4 Lymphocyte Count; Drug Therapy, Combination; Enzyme Inhibitors; Female; HIV Infections; Humans; Hydroxyurea; Indinavir; Lamivudine; Male; Nucleic Acid Synthesis Inhibitors; Pancreatitis; Prospective Studies; Survival Analysis; Treatment Failure; Viral Load; Zidovudine	2001
Time-dependent changes in HIV nucleoside analogue phosphorylation and the effect of hydroxyurea. AIDS (London, England), 2002, Dec-06, Volume: 16, Issue:18 Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Drug Interactions; Drug Resistance, Viral; Female; HIV Infections; Humans; Hydroxyurea; Lamivudine; Leukocytes, Mononuclear; Male; Middle Aged; Nevirapine; Nucleosides; Phosphorylation; Reverse Transcriptase Inhibitors; Zidovudine	2002
Hydroxyurea in combination with didanosine and stavudine in antiretroviral-experienced HIV-infected subjects with a review of the literature. International journal of STD & AIDS, 2003, Volume: 14, Issue:5 Topics: Adult; Anti-HIV Agents; Antineoplastic Agents; Antiretroviral Therapy, Highly Active; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Hydroxyurea; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Viral Load; Zidovudine	2003

Other Studies

46 other study(ies) available for hydroxyurea and zidovudine

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
Drug Metabolism by the Mitochondrial Amidoxime Reducing Component (mARC): Rapid Assay and Identification of New Substrates. Journal of medicinal chemistry, 2020, 06-25, Volume: 63, Issue:12 Topics: Biological Assay; Humans; Inactivation, Metabolic; Metabolic Clearance Rate; Mitochondria; Mitochondrial Proteins; Oxidation-Reduction; Oxidoreductases; Oximes; Substrate Specificity	2020
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
Hydroxyurea increases the phosphorylation of 3'-fluorothymidine and 3'-azidothymidine in CEM cells. European journal of biochemistry, 1989, Dec-22, Volume: 186, Issue:3 Topics: Antiviral Agents; Cell Division; Cell Line; Deoxyribonucleotides; Dideoxynucleosides; Humans; Hydroxyurea; Kinetics; Phosphorylation; Tumor Cells, Cultured; Zidovudine	1989
Disparate actions of hydroxyurea in potentiation of purine and pyrimidine 2',3'-dideoxynucleoside activities against replication of human immunodeficiency virus. Proceedings of the National Academy of Sciences of the United States of America, 1995, Aug-29, Volume: 92, Issue:18 Topics: Adenosine Kinase; Cells, Cultured; Didanosine; DNA Replication; Drug Synergism; HIV-1; Humans; Hydroxyurea; Phosphorylation; Proviruses; Uridine Kinase; Virus Replication; Zalcitabine; Zidovudine	1995
Anti-human immunodeficiency virus type 1 activity of hydroxyurea in combination with 2',3'-dideoxynucleosides. Molecular pharmacology, 1994, Volume: 46, Issue:4 Topics: Antiviral Agents; Cells, Cultured; Didanosine; Dideoxynucleosides; Drug Synergism; HIV-1; Humans; Hydroxyurea; Virus Replication; Zalcitabine; Zidovudine	1994
Synergistic anti-human immunodeficiency virus type 1 effect of hydroxamate compounds with 2',3'-dideoxyinosine in infected resting human lymphocytes. Proceedings of the National Academy of Sciences of the United States of America, 1994, Nov-08, Volume: 91, Issue:23 Topics: Antiviral Agents; Asparagine; Aspartic Acid; Cell Survival; Cells, Cultured; Didanosine; Drug Synergism; HIV Infections; Humans; Hydroxyurea; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Virus Replication; Zalcitabine; Zidovudine	1994
Hydroxyurea as an inhibitor of human immunodeficiency virus-type 1 replication. Science (New York, N.Y.), 1994, Nov-04, Volume: 266, Issue:5186 Topics: Acquired Immunodeficiency Syndrome; Cell Survival; Didanosine; DNA Replication; DNA, Viral; Dose-Response Relationship, Drug; Drug Synergism; HIV Core Protein p24; HIV-1; Humans; Hydroxyurea; Leukocytes, Mononuclear; Lymphocyte Activation; Macrophage Activation; Macrophages; Virus Replication; Zidovudine	1994
Potentiation of 2',3'-dideoxycytidine (ddC) by hydroxyurea and thymidine on the Moloney murine leukemia virus (MoMLV) early replicative steps. Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie, 1994, Volume: 317, Issue:5 Topics: 3T3 Cells; Animals; Drug Synergism; Hydroxyurea; Mice; Moloney murine leukemia virus; Thymidine; Transcription, Genetic; Virus Replication; Zalcitabine; Zidovudine	1994
Hydroxyurea enhances 3'-azido-3'-deoxythymidine (AZT) cytotoxicity in human chronic myeloid leukemia models. European journal of haematology, 1994, Volume: 52, Issue:5 Topics: Bone Marrow; Bone Marrow Cells; Cells, Cultured; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Drug Synergism; Humans; Hydroxyurea; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Tumor Cells, Cultured; Zidovudine	1994
Inhibition of ribonucleotide reductase by 2'-substituted deoxycytidine analogs: possible application in AIDS treatment. Proceedings of the National Academy of Sciences of the United States of America, 1994, Aug-30, Volume: 91, Issue:18 Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cells, Cultured; Cytidine; Deoxycytidine; Gemcitabine; Humans; Hydroxyurea; In Vitro Techniques; Prodrugs; Ribonucleotide Reductases; Zidovudine	1994
Synergistic antiviral action of ribonucleotide reductase inhibitors and 3'-azido-3'-deoxythymidine on HIV type 1 infection in vitro. AIDS research and human retroviruses, 1996, May-20, Volume: 12, Issue:8 Topics: Antiviral Agents; Cell Cycle; Cytidine; Drug Synergism; Enzyme Inhibitors; HIV Core Protein p24; HIV-1; Humans; Hydroxyurea; Leukocytes, Mononuclear; Phosphorylation; Reverse Transcriptase Inhibitors; Ribonucleotide Reductases; Thymine Nucleotides; Tumor Cells, Cultured; Virus Replication; Zidovudine	1996
Increased activation of the combination of 3'-azido-3'-deoxythymidine and 2'-deoxy-3'-thiacytidine in the presence of hydroxyurea. Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:2 Topics: Anti-HIV Agents; Cell Line; Deoxycytosine Nucleotides; Drug Synergism; Hydroxyurea; Lamivudine; Phosphorylation; Thymine Nucleotides; Zidovudine	1997
Metabolism and activities of 3'-azido-2',3'-dideoxythymidine and 2',3'-didehydro-2',3'-dideoxythymidine in herpesvirus thymidine kinase transduced T-lymphocytes. Antiviral research, 1997, Volume: 35, Issue:3 Topics: Acyclovir; Cell Line; Dose-Response Relationship, Drug; Ganciclovir; Genetic Therapy; Growth Inhibitors; Herpesvirus 1, Human; HIV-1; Humans; Hydroxyurea; Nucleosides; Stavudine; Substrate Specificity; T-Lymphocytes; Thymidine Kinase; Zalcitabine; Zidovudine	1997
Therapeutic advantage of hydroxyurea and didanosine combination therapy in patients previously treated with zidovudine. AIDS (London, England), 1998, Jun-18, Volume: 12, Issue:9 Topics: Anti-HIV Agents; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Hydroxyurea; Retrospective Studies; Reverse Transcriptase Inhibitors; Zidovudine	1998
Deoxyribonucleoside triphosphate pool imbalances in vivo are associated with an increased retroviral mutation rate. Journal of virology, 1998, Volume: 72, Issue:10 Topics: Cell Line; Deoxyribonucleotides; Genetic Vectors; Hydroxyurea; Mutation; Retroviridae; Thymidine; Zidovudine	1998
Intracellular activation of 2',3'-dideoxyinosine and drug interactions in vitro. AIDS research and human retroviruses, 1999, Jun-10, Volume: 15, Issue:9 Topics: Anti-HIV Agents; Deoxyadenine Nucleotides; Didanosine; Dideoxynucleotides; Drug Interactions; Guanosine; Humans; Hydroxyurea; Inosine; Intracellular Fluid; Lamivudine; Pentoxifylline; Stavudine; U937 Cells; Zidovudine	1999
Hydroxyurea interferes with antigen-dependent T-cell activation in vitro. European journal of clinical investigation, 2000, Volume: 30, Issue:2 Topics: Candida albicans; HIV-1; Humans; Hydroxyurea; Lamivudine; Lymphocyte Activation; Phytohemagglutinins; Reverse Transcriptase Inhibitors; T-Lymphocytes; Zidovudine	2000
Synergistic inhibition of HIV-1 in activated and resting peripheral blood mononuclear cells, monocyte-derived macrophages, and selected drug-resistant isolates with nucleoside analogues combined with a natural product, resveratrol. Journal of acquired immune deficiency syndromes (1999), 2000, Nov-01, Volume: 25, Issue:3 Topics: Cell Division; Didanosine; Dose-Response Relationship, Drug; Drug Resistance; Drug Synergism; HIV-1; Humans; Hydroxyurea; Leukocytes, Mononuclear; Macrophages; Nucleosides; Resveratrol; Stilbenes; Virus Replication; Zalcitabine; Zidovudine	2000
Reduction in CD8+ cell noncytotoxic anti-HIV activity in individuals receiving highly active antiretroviral therapy during primary infection. Proceedings of the National Academy of Sciences of the United States of America, 2001, Jan-16, Volume: 98, Issue:2 Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Depression, Chemical; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Hydroxyurea; Immunity, Cellular; Indinavir; Lamivudine; Lymphocyte Count; Male; Middle Aged; Nelfinavir; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Treatment Refusal; Viral Load; Viremia; Zidovudine	2001
Incidence of pancreatitis in HIV-infected patients receiving nucleoside reverse transcriptase inhibitor drugs. AIDS (London, England), 2001, Mar-30, Volume: 15, Issue:5 Topics: Adult; Amylases; Anti-HIV Agents; Didanosine; Female; HIV Infections; HIV-1; Humans; Hydroxyurea; Incidence; Lipase; Longitudinal Studies; Male; Pancreatitis; Reverse Transcriptase Inhibitors; Stavudine; United States; Zidovudine	2001
A Lisbon traviata. Are clinicians ready to sing addio to monotherapy and libiamo to combinations? Journal of the International Association of Physicians in AIDS Care, 1995, Volume: 1, Issue:8 Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; HIV; HIV Infections; Humans; Hydroxyurea; Indinavir; Interleukin-2; Lamivudine; Mutation; Pyridines; RNA, Viral; Zalcitabine; Zidovudine	1995
Update on clinical trials of combination therapies for HIV infection. NIAID AIDS agenda, 1995 Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Child; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Hydroxyurea; Lamivudine; RNA-Directed DNA Polymerase; Stavudine; Zalcitabine; Zidovudine	1995
Dethroning AZT. GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1997, Volume: 11, Issue:2 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Hydroxyurea; Lamivudine; Oxazines; Stavudine; Viral Load; Zidovudine	1997
Drug research shows easier dosing, new combinations are making gains. AIDS alert, 1998, Volume: 13, Issue:4 Topics: Anti-HIV Agents; Clinical Trials as Topic; Drug Combinations; Drug Therapy; Drug Therapy, Combination; Enzyme Inhibitors; HIV Infections; HIV Protease Inhibitors; Humans; Hydroxyurea; Salvage Therapy; Stavudine; United States; Zidovudine	1998
A new approach to initial antiretroviral therapy: protease-sparing combination regimens. BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation, 1998 Topics: Alkynes; Anti-HIV Agents; Antineoplastic Agents; Benzoxazines; Clinical Trials as Topic; Cyclopropanes; Dideoxynucleosides; Drug Resistance, Microbial; Drug Therapy, Combination; Drugs, Investigational; HIV Infections; HIV Protease Inhibitors; Humans; Hydroxyurea; Lamivudine; Lipodystrophy; Oxazines; Reverse Transcriptase Inhibitors; Time Factors; Zidovudine	1998
Hydroxyurea, a potential new anti-HIV agent. GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:1 Topics: Didanosine; DNA Replication; Drug Therapy, Combination; HIV; HIV Infections; Humans; Hydroxyurea; Leukocytes, Mononuclear; Virus Replication; Zalcitabine; Zidovudine	1995
The additive in vitro anti-HIV-1 effect of chloroquine, when combined with zidovudine and hydroxyurea. Biochemical pharmacology, 2001, Jun-15, Volume: 61, Issue:12 Topics: Anti-HIV Agents; Chloroquine; Drug Synergism; HIV-1; Humans; Hydroxyurea; Microbial Sensitivity Tests; Zidovudine	2001
Combined effect of zidovudine (ZDV), lamivudine (3TC) and abacavir (ABC) antiretroviral therapy in suppressing in vitro FIV replication. Antiviral research, 2002, Volume: 53, Issue:1 Topics: Animals; Anti-HIV Agents; Cats; Cell Line; Dideoxynucleosides; Drug Synergism; Drug Therapy, Combination; Feline Acquired Immunodeficiency Syndrome; Humans; Hydroxyurea; Immunodeficiency Virus, Feline; Kidney; Lamivudine; Reverse Transcriptase Inhibitors; Virus Replication; Zidovudine	2002
When will once (-a day) be enough? The Hopkins HIV report : a bimonthly newsletter for healthcare providers, 2000, Volume: 12, Issue:3 Topics: Acquired Immunodeficiency Syndrome; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Deoxycytidine; Didanosine; Emtricitabine; Humans; Hydroxyurea; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Zidovudine	2000
Combination of drugs and drug-resistant reverse transcriptase results in a multiplicative increase of human immunodeficiency virus type 1 mutant frequencies. Journal of virology, 2002, Volume: 76, Issue:18 Topics: Animals; Anti-HIV Agents; COS Cells; Dose-Response Relationship, Drug; Drug Resistance, Viral; Genetic Vectors; HeLa Cells; HIV Reverse Transcriptase; HIV-1; Humans; Hydroxyurea; Lamivudine; Mutation; Reverse Transcriptase Inhibitors; Thymidine; Virus Replication; Zidovudine	2002
Azidothymidine inhibits NF-kappaB and induces Epstein-Barr virus gene expression in Burkitt lymphoma. Blood, 2005, Jul-01, Volume: 106, Issue:1 Topics: Apoptosis; Burkitt Lymphoma; Epstein-Barr Virus Infections; Gene Expression Profiling; Gene Expression Regulation, Viral; Genome, Viral; Herpesvirus 4, Human; Humans; Hydroxyurea; NF-kappa B; Phosphorylation; Reverse Transcriptase Inhibitors; Transcription Factor RelA; Tumor Cells, Cultured; Zidovudine	2005
The role of replication initiation control in promoting survival of replication fork damage. Molecular microbiology, 2006, Volume: 60, Issue:1 Topics: Bacterial Outer Membrane Proteins; Bacterial Proteins; DNA Damage; DNA Replication; DNA-Binding Proteins; DNA, Bacterial; Escherichia coli K12; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Hydroxyurea; Mutation; Replication Origin; Site-Specific DNA-Methyltransferase (Adenine-Specific); Ultraviolet Rays; Zidovudine	2006
Amphiphilic lipid derivatives of 3'-hydroxyurea-deoxythymidine: preparation, properties, molecular self-assembly, simulation and in vitro anticancer activity. Colloids and surfaces. B, Biointerfaces, 2014, Nov-01, Volume: 123 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Humans; Hydroxyurea; In Vitro Techniques; Nanostructures; Thymidine; Zidovudine	2014
Surmounting Cytarabine-resistance in acute myeloblastic leukemia cells and specimens with a synergistic combination of hydroxyurea and azidothymidine. Cell death & disease, 2019, 05-17, Volume: 10, Issue:6 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cytarabine; Deoxycytidine Kinase; DNA Damage; Drug Resistance, Neoplasm; Drug Synergism; Histones; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Ubiquitination; Zidovudine	2019