hydroxyurea and warfarin

hydroxyurea has been researched along with warfarin in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.45)18.7374
1990's8 (27.59)18.2507
2000's8 (27.59)29.6817
2010's12 (41.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Kinoshita, S; Matsubuchi, T; Matsumiya, K; Nishimura, K; Oka, T; Takaha, M; Tsujimura, A; Yasui, M; Yasunaga, Y1
Georgieff, KK1
Arbustini, E; Campana, C; Faggiano, P; Lanzani, G; Lombardi, C; Rusconi, C1
Bopp, BA; Kukulka, MJ; Machinist, JM1
Awni, WM; Cavanaugh, JH; Dubé, LM; Granneman, GR; Hussein, Z; Patterson, KJ1
Lau, R1
Langnas, AN1
Miyauchi, Y; Nakajima, N; Ohto, T; Shihara, H1
Fabris, F; Girolami, A; Randi, ML; Rossi, C1
Aslan, V; Entok, E1
Arndt, CA; Jensen, AW; Tefferi, A1
Reilly, JT1
Chordia, MD; Li, F; Macdonald, TL; Woodling, KA1
Chinnakotla, S; Davis, GL; Goldstein, RM; Kim, P; Klintmalm, E; Klintmalm, GB; Landaverde, C; Levy, MF; Saad, R; Stone, MJ; Tomiyama, K; Trotter, JF1
Vishwanath, M; Williams, MW1
Hirano, T; Isoda, K; Ito, K; Naganuma, M; Nishi, S1
Bretzke, S; Essig, S; Koeberle, A; Menche, D; Müller, R; Scherer, O; Schmalzbauer, B; Werz, O1
Ahmed, AK; Skeik, N; Youssef, A1

Reviews

2 review(s) available for hydroxyurea and warfarin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Budd-Chiari syndrome: decisions, decisions.
    Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 1997, Volume: 3, Issue:4

    Topics: Budd-Chiari Syndrome; Diuretics; Drug Therapy, Combination; Humans; Hydroxyurea; Liver Transplantation; Warfarin

1997

Trials

2 trial(s) available for hydroxyurea and warfarin

ArticleYear
Pharmacodynamic and stereoselective pharmacokinetic interactions between zileuton and warfarin in humans.
    Clinical pharmacokinetics, 1995, Volume: 29 Suppl 2

    Topics: Administration, Oral; Adult; Analysis of Variance; Anticoagulants; Blood Coagulation; Blood Specimen Collection; Chromatography, High Pressure Liquid; Double-Blind Method; Drug Interactions; Humans; Hydroxyurea; Lipoxygenase Inhibitors; Male; Prothrombin Time; Reproducibility of Results; Stereoisomerism; Warfarin

1995
Drug interactions with zileuton.
    Lancet (London, England), 1997, May-17, Volume: 349, Issue:9063

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Bronchodilator Agents; Double-Blind Method; Drug Interactions; Humans; Hydroxyurea; Lipoxygenase Inhibitors; Theophylline; Warfarin

1997

Other Studies

25 other study(ies) available for hydroxyurea and warfarin

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
[Clinical experience of urological surgery of the patients with hemostatic disorder or hemolytic disease].
    Hinyokika kiyo. Acta urologica Japonica, 1992, Volume: 38, Issue:11

    Topics: Adult; Aged; Blood Coagulation Factors; Blood Transfusion, Autologous; Child; Child, Preschool; Factor VIII; Female; Fibrinogen; Hemophilia B; Humans; Hydroxyurea; Lithotripsy; Male; Middle Aged; Spherocytosis, Hereditary; Thrombocythemia, Essential; Urologic Diseases; von Willebrand Diseases; Warfarin

1992
Free radical inhibitory effect of some anticancer compounds.
    Science (New York, N.Y.), 1971, Aug-06, Volume: 173, Issue:3996

    Topics: Aldehydes; Alkylating Agents; Animals; Anti-Bacterial Agents; Antimetabolites; Antineoplastic Agents; Ascorbic Acid; Carbamates; Copper; Coumarins; Drug Synergism; Free Radicals; Gonadal Steroid Hormones; Hydroxyurea; Mice; Phenols; Prednisone; Vitamin A

1971
Successful reduction of endomyocardial fibrosis in a patient with idiopathic hypereosinophilic syndrome. A case report.
    Angiology, 1995, Volume: 46, Issue:4

    Topics: Dipyridamole; Drug Therapy, Combination; Echocardiography, Doppler; Endomyocardial Fibrosis; Female; Humans; Hydroxyurea; Hypereosinophilic Syndrome; Magnetic Resonance Imaging; Middle Aged; Prednisone; Warfarin

1995
In vitro plasma protein binding of zileuton and its N-dehydroxylated metabolite.
    Clinical pharmacokinetics, 1995, Volume: 29 Suppl 2

    Topics: Adult; Anti-Allergic Agents; Anti-Inflammatory Agents; Anticoagulants; Blood Proteins; Chromatography, High Pressure Liquid; Drug Interactions; Female; Hematocrit; Humans; Hydroxylation; Hydroxyurea; Ibuprofen; In Vitro Techniques; Isotope Labeling; Lipoxygenase Inhibitors; Male; Naproxen; Prednisolone; Protein Binding; Salicylates; Stereoisomerism; Terfenadine; Theophylline; Warfarin

1995
Zileuton for asthma.
    The Medical letter on drugs and therapeutics, 1997, Feb-28, Volume: 39, Issue:995

    Topics: Adolescent; Adult; Asthma; Child; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Drug Interactions; Humans; Hydroxyurea; Intestinal Absorption; Leukotrienes; Lipoxygenase Inhibitors; Propranolol; Theophylline; Warfarin

1997
[A case of coronary artery bypass surgery using left internal thoracic artery and right gastroepiploic artery for a patient with essential thrombocythemia].
    The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai zasshi, 1998, Volume: 46, Issue:8

    Topics: Aged; Angina Pectoris; Coronary Artery Bypass; Fatal Outcome; Humans; Hydroxyurea; Male; Omentum; Stomach; Thoracic Arteries; Thrombocythemia, Essential; Warfarin

1998
Essential thrombocythemia in young adults: major thrombotic complications and complications during pregnancy--a follow-up study in 68 patients.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2000, Volume: 6, Issue:1

    Topics: Acute Disease; Adult; Age Factors; Arteriosclerosis; Aspirin; Busulfan; Cohort Studies; Disease-Free Survival; Female; Follow-Up Studies; Hemorrhage; Heparin; Humans; Hydroxyurea; Leukemia; Male; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Complications, Hematologic; Pregnancy Outcome; Primary Myelofibrosis; Prospective Studies; Risk Factors; Splenectomy; Thrombocythemia, Essential; Venous Thrombosis; Warfarin

2000
Factor V Leiden mutation and deep venous thrombosis in a patient with hypereosinophilic syndrome.
    Saudi medical journal, 2006, Volume: 27, Issue:9

    Topics: Adult; Anticoagulants; Coumarins; Enzyme Inhibitors; Factor V; Heparin, Low-Molecular-Weight; Humans; Hydroxyurea; Hypereosinophilic Syndrome; Leg; Male; Mutation; Radionuclide Imaging; Venous Thrombosis

2006
Cerebral venous sinus thrombosis associated with essential thrombocytosis in a pediatric patient.
    Journal of pediatric hematology/oncology, 2007, Volume: 29, Issue:3

    Topics: Adolescent; Anticoagulants; Aspirin; Bone Marrow; Follow-Up Studies; Humans; Hydroxyurea; Magnetic Resonance Angiography; Male; Mucositis; Platelet Count; Sensitivity and Specificity; Sinus Thrombosis, Intracranial; Thrombocytosis; Treatment Outcome; Warfarin

2007
Practical approach to treating essential thrombocythaemia: case studies.
    European journal of haematology. Supplementum, 2007, Issue:68

    Topics: Adult; Aspirin; Disease Management; Female; Humans; Hydroxyurea; Interferon-alpha; Leg Ulcer; Male; Middle Aged; Pipobroman; Platelet Count; Pregnancy; Pregnancy Complications, Hematologic; Quinazolines; Thrombocythemia, Essential; Warfarin

2007
Irreversible alkylation of human serum albumin by zileuton metabolite 2-acetylbenzothiophene-S-oxide: a potential model for hepatotoxicity.
    Chemical research in toxicology, 2007, Volume: 20, Issue:12

    Topics: Alkylation; Anti-Asthmatic Agents; Binding, Competitive; Chemical and Drug Induced Liver Injury; Chromatography, Liquid; Half-Life; Humans; Hydroxyurea; Ibuprofen; Models, Biological; Serum Albumin; Tandem Mass Spectrometry; Thiophenes; Warfarin

2007
Long-term follow-up of liver transplantation for Budd-Chiari syndrome with antithrombotic therapy based on the etiology.
    Transplantation, 2011, Aug-15, Volume: 92, Issue:3

    Topics: Adolescent; Adult; Anticoagulants; Aspirin; Budd-Chiari Syndrome; Child; Female; Fibrinolytic Agents; Follow-Up Studies; Graft Survival; Hepatic Artery; Humans; Hydroxyurea; Liver Transplantation; Male; Middle Aged; Platelet Aggregation Inhibitors; Portal Vein; Postoperative Complications; Thrombosis; Warfarin; Young Adult

2011
Intracranial hypertension: was it really idiopathic?
    BMJ case reports, 2011, Apr-19, Volume: 2011

    Topics: Acetazolamide; Adult; Anticoagulants; Anticonvulsants; Diagnosis, Differential; Drug Therapy, Combination; Female; Headache; Humans; Hydroxyurea; Intracranial Hypertension; Pseudotumor Cerebri; Thrombocytopenia; Warfarin

2011
Repeated episodes of ischemic stroke over a short period in a patient with essential thrombocythemia on anticoagulant therapy.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2014, Volume: 23, Issue:1

    Topics: Aged; Anticoagulants; Aphasia; Brain Ischemia; Cerebral Angiography; Cilostazol; Diffusion Magnetic Resonance Imaging; Hemiplegia; Humans; Hydroxyurea; Infarction, Middle Cerebral Artery; International Normalized Ratio; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Male; Perceptual Disorders; Platelet Aggregation Inhibitors; Stroke; Tetrazoles; Thrombocythemia, Essential; Warfarin

2014
Predictive Bioinformatic Assignment of Methyl-Bearing Stereocenters, Total Synthesis, and an Additional Molecular Target of Ajudazol B.
    The Journal of organic chemistry, 2016, Feb-19, Volume: 81, Issue:4

    Topics: Arachidonate 5-Lipoxygenase; Biological Products; Computational Biology; Coumarins; Humans; Hydroxyurea; Stereoisomerism

2016
Medical Management of Extensive Arterial Thromboembolism in a Patient with Essential Thrombocythemia and Warfarin Failure.
    Annals of vascular surgery, 2017, Volume: 42

    Topics: Anticoagulants; Arterial Occlusive Diseases; Blood Coagulation; Blood Coagulation Tests; Computed Tomography Angiography; Drug Substitution; Enoxaparin; Humans; Hydroxyurea; Male; Middle Aged; Thrombocythemia, Essential; Thromboembolism; Treatment Failure; Treatment Outcome; Warfarin

2017