hydroxyurea and uracil

hydroxyurea has been researched along with uracil in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199024 (82.76)18.7374
1990's1 (3.45)18.2507
2000's3 (10.34)29.6817
2010's1 (3.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Davies, J; Schindler, D1
Blocker, R; Roth, JS1
Ariga, H; Shimojo, H1
Betz, H1
Grodzinsky, DM; Gudkov, IN1
Fogt, SM; Price, AR1
Lazdunski, A; Shapiro, BM; Siccardi, AG1
Krijzer, FN; Moors, J; Wanka, F1
Hotta, Y; Stern, H1
Sinha, NK; Snustad, DP1
Slater, ML1
Deering, RA; Kantor, GJ1
Hobbs, MD; Warner, HR1
Rosenkranz, HS1
Carr, HS; Hjorth, R; Rosenkranz, HS1
Carr, HS; Ellner, CJ; Mednis, A; Rosenkranz, HS; Winshell, EB1
Kumar, HD; Singh, MK1
Feinendegen, LE1
Carr, HS; Morgan, C; Rose, HM; Rosenkranz, HS1
Kallio, T; Kukko, E1
Böhmer, FD; Graetz, H; Grosse, R; Langen, P; Lehmann, W1
García, E; López, R; Ronda, C1
Cánovas, JL; Cuadrado, A; Navarrete, MH1
Brockstein, BE; Haraf, DJ; Humerickhouse, R; Vokes, EE1
Aoki, K; Chiba, S; Hirai, H; Honda, H; Horikoshi, M; Itikawa, M; Kurokawa, M; Machida, U; Masuda, S; Mitani, K; Ogawa, S; Seo, S; Sunaga, S; Yazaki, Y1
Aabo, K; Hansen, F; Jakobsen, A; Pfeiffer, P; Sandberg, E1
LEVY, JA; ROSENKRANZ, HS1
Horikoshi, M; Matsubara, K; Sano, N; Umehara, T1

Reviews

2 review(s) available for hydroxyurea and uracil

ArticleYear
Inhibitors of macromolecular synthesis in yeast.
    Methods in cell biology, 1975, Volume: 12

    Topics: Acriflavine; Amphotericin B; Anisomycin; Anti-Bacterial Agents; Antineoplastic Agents; Cycloheximide; Dactinomycin; Daunorubicin; Deoxyadenosines; Depression, Chemical; DNA; Ethidium; Fluorouracil; Fungal Proteins; Hydroxyurea; Mitomycins; Nalidixic Acid; Phenazines; Phenylethyl Alcohol; Porfiromycin; Puromycin; RNA; Saccharomyces cerevisiae; Streptonigrin; Sulfanilamides; Triaziquone; Trichothecenes; Uracil

1975
Oral 5-FU alternatives for the treatment of head and neck cancer.
    Oncology (Williston Park, N.Y.), 1998, Volume: 12, Issue:10 Suppl 7

    Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Etoposide; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Neoplasm Recurrence, Local; Tegafur; Uracil

1998

Trials

1 trial(s) available for hydroxyurea and uracil

ArticleYear
Dual modulation of UFT with leucovorin and hydroxyurea in metastatic colorectal cancer.
    Acta oncologica (Stockholm, Sweden), 2001, Volume: 40, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Disease-Free Survival; Drug Interactions; Female; Humans; Hydroxyurea; Leucovorin; Male; Middle Aged; Neoplasm Metastasis; Tegafur; Uracil

2001

Other Studies

26 other study(ies) available for hydroxyurea and uracil

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
The reduction of uridine 5'-diphosphate and uridine 5'-triphosphate in some transplantable rat hepatomas.
    Cancer research, 1977, Volume: 37, Issue:6

    Topics: Animals; Carcinoma, Hepatocellular; Deoxyribonucleosides; Deoxyribonucleotides; Hydrolysis; Hydroxyurea; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Oxidation-Reduction; Rats; Ribonucleotide Reductases; Uracil; Uracil Nucleotides; Uridine; Uridine Diphosphate Glucose; Uridine Monophosphate

1977
Incorporation of uracil into the growing strand of adenovirus 12 DNA.
    Biochemical and biophysical research communications, 1979, Mar-30, Volume: 87, Issue:2

    Topics: Adenoviruses, Human; Deoxycytidine; DNA Repair; DNA Replication; DNA, Viral; Hydroxyurea; Molecular Weight; Uracil; Uridine; Virus Replication

1979
Inhibition of protein synthesis stimulates intracellular protein degradation in growing yeast cells.
    Biochemical and biophysical research communications, 1976, Sep-07, Volume: 72, Issue:1

    Topics: Amino Acids; Cell Division; Cycloheximide; Fungal Proteins; Hydroxyquinolines; Hydroxyurea; Kinetics; Mutation; Protein Biosynthesis; Saccharomyces cerevisiae; Species Specificity; Temperature; Uracil

1976
Induction by gamma-radiation of DNA synthesis in radicle cells of germinating seeds of Pisum sativum l.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1976, Volume: 29, Issue:5

    Topics: Acriflavine; Caffeine; Cobalt Radioisotopes; DNA Repair; DNA Replication; Gamma Rays; Hydroxyurea; Radiation Genetics; Seeds; Uracil

1976
Effect of nalidixic acid on PBS2 bacteriophage infection of Bacillus subtilis.
    Journal of virology, 1973, Volume: 12, Issue:2

    Topics: Bacillus subtilis; Bacteriophages; Colorimetry; DNA, Bacterial; DNA, Viral; Hydroxyurea; Nalidixic Acid; Thymine; Time Factors; Uracil; Virus Replication

1973
Interrelationship between membrane protein composition and deoxyribonucleic acid synthesis in Escherichia coli.
    Biochemistry, 1972, Apr-25, Volume: 11, Issue:9

    Topics: Amino Acids; Azo Compounds; Bacterial Proteins; Carbon Isotopes; Cell Membrane; DNA, Bacterial; Electrophoresis; Escherichia coli; Floxuridine; Genetics, Microbial; Hydroxyurea; Isotope Labeling; Leucine; Mitomycins; Mutation; Nalidixic Acid; Penicillins; Sodium Dodecyl Sulfate; Temperature; Thymine; Tritium; Uracil

1972
Dissociation of nuclear DNA replication from concomitant protein synthesis in synchronous cultures of Chlorella.
    Biochimica et biophysica acta, 1972, Apr-26, Volume: 269, Issue:1

    Topics: Carbon Isotopes; Centrifugation, Density Gradient; Chlorella; Chlorophyta; Chromatography; Cycloheximide; Darkness; DNA; DNA Replication; Hydroxyurea; Light; Methylation; Protein Biosynthesis; Radiation Effects; RNA; Serum Albumin; Silicon Dioxide; Time Factors; Uracil

1972
DNA metabolism during pachytene in relation to crossing over.
    Genetics, 1974, Volume: 78, Issue:1

    Topics: Centrifugation, Density Gradient; Chromatin; Crossing Over, Genetic; DNA; DNA Repair; Hydroxyurea; Meiosis; Organoids; Plants; Thymidine; Tritium; Uracil

1974
Mechanism of inhibition of deoxyribonucleic acid synthesis in Escherichia coli by hydroxyurea.
    Journal of bacteriology, 1972, Volume: 112, Issue:3

    Topics: Bacterial Proteins; Carbon Isotopes; Cell Survival; Cell-Free System; Centrifugation, Density Gradient; Chromatography; Cytosine Nucleotides; Deoxyribonucleotides; DNA Repair; DNA Replication; DNA, Bacterial; Escherichia coli; Hydroxyurea; Nucleotides; Oxidoreductases; Pyrimidine Nucleotides; Ribonucleotides; RNA, Bacterial; Thymidine; Toluene; Tritium; Uracil

1972
Recovery of yeast from transient inhibition of DNA synthesis.
    Nature, 1974, Feb-01, Volume: 247, Issue:5439

    Topics: Anti-Bacterial Agents; Benzyl Compounds; Carbon Radioisotopes; Cell Division; Cell Nucleus; Depression, Chemical; DNA; Fungal Proteins; Hydroxyurea; Kinetics; Pyrrolidines; Saccharomyces cerevisiae; Uracil

1974
Effect of nalidixic acid and hydroxyurea on division ability of Escherichia coli fil+ and lon- strains.
    Journal of bacteriology, 1968, Volume: 95, Issue:2

    Topics: Bacterial Proteins; Carbon Isotopes; Cell Division; DNA Replication; DNA, Bacterial; Escherichia coli; Hydroxyurea; Lactones; Nalidixic Acid; RNA, Bacterial; Thymidine; Tritium; Uracil

1968
Effect of hydroxyurea on replication of bacteriophage T4 in Escherichia coli.
    Journal of virology, 1969, Volume: 3, Issue:3

    Topics: Carbon Isotopes; Coliphages; DNA, Bacterial; DNA, Viral; Escherichia coli; Hydroxyurea; Nucleotides; Thymidine; Uracil; Virus Replication

1969
Some biological effects of carbamoyloxyurea, an oxidation product of hydroxyurea.
    Journal of bacteriology, 1970, Volume: 102, Issue:1

    Topics: Anti-Bacterial Agents; Azides; Bacterial Proteins; Carbon Isotopes; Chloramphenicol; DNA, Bacterial; Escherichia coli; Genetics, Microbial; Hydroxyurea; Lysine; Mutation; RNA, Bacterial; Sodium; Thymidine; Tritium; Uracil; Uridine

1970
Studies with hydroxyurea. The biologic and metabolic properties of formamidoxime.
    Biochimica et biophysica acta, 1971, Feb-25, Volume: 232, Issue:1

    Topics: Amides; Arsenic; Ascitic Fluid; Azides; Chemical Phenomena; Chemistry, Physical; Chloramphenicol; DNA; DNA Nucleotidyltransferases; DNA, Bacterial; Drug Stability; Drug Synergism; Escherichia coli; Formamides; Hydroxyurea; Mutation; Oximes; Puromycin; Ribosomes; RNA, Bacterial; Tritium; Uracil

1971
Studies with hydroxyurea. VII. Hydroxyurea and the synthesis of functional proteins.
    Journal of bacteriology, 1967, Volume: 94, Issue:4

    Topics: Alkaline Phosphatase; Bacterial Proteins; Carbon Isotopes; Chloramphenicol; DNA, Bacterial; Electrophoresis; Escherichia coli; Hydroxyurea; Immunodiffusion; Lysine; Precipitin Tests; RNA, Bacterial; RNA, Messenger; Thymidine; Transformation, Genetic; Tritium; Uracil; Uridine

1967
Action of hydroxyurea on Anabaena variabilis. II. Effects of pre- and post-treatment with chloramphenicol and base analogues.
    Archiv fur Mikrobiologie, 1969, Volume: 67, Issue:1

    Topics: Adenine; Amines; Azaguanine; Chloramphenicol; Cyanobacteria; Depression, Chemical; DNA; Drug Antagonism; Hydroxyurea; Protein Biosynthesis; Uracil

1969
[Cellular aspects of radiation sensitization].
    Strahlentherapie, 1972, Volume: 143, Issue:3

    Topics: Acetamides; Anti-Bacterial Agents; Cells; DNA; DNA Repair; Hydroxyurea; Maleimides; Mitosis; Oxygen; Oxygen Consumption; Periodicity; Radiation Effects; Radiation-Sensitizing Agents; Radiotherapy; Uracil

1972
Electron microscopy of chloramphenicol-treated Escherichia coli.
    Journal of bacteriology, 1967, Volume: 93, Issue:6

    Topics: Azides; Cell Division; Chloramphenicol; Escherichia coli; Hydroxyurea; Microscopy, Electron; Uracil

1967
Accumulation of pyrophosphate correlates with the increased level of nucleoside triphosphates in Escherichia coli.
    Biochemistry international, 1984, Volume: 8, Issue:1

    Topics: Adenosine Triphosphate; Chromatography, High Pressure Liquid; Diphosphates; Escherichia coli; Fluorouracil; Hydroxyurea; Luminescent Measurements; Mercaptopurine; Mutation; Ribonucleotides; Species Specificity; Uracil

1984
Is ribonucleotide reductase in Ehrlich ascites mammary tumour cells the target of a growth inhibitor purified from bovine mammary gland?
    Biomedica biochimica acta, 1984, Volume: 43, Issue:12

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cattle; Cells, Cultured; Cytidine; Deoxycytidine; Deoxyuridine; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; Female; Growth Inhibitors; Hydroxyurea; Insulin; Mammary Glands, Animal; Mice; Nucleosides; Ribonucleotide Reductases; Uracil; Uridine

1984
Selective replication of diplophage Dp-4 deoxyribonucleic acid in 6-(p-hydroxyphenylazo)-uracil treated Streptococcus pneumoniae.
    FEBS letters, 1980, Feb-25, Volume: 111, Issue:1

    Topics: Bacteriophages; DNA Replication; DNA, Bacterial; DNA, Viral; Floxuridine; Hydroxyphenylazouracil; Hydroxyurea; Kinetics; Nalidixic Acid; Streptococcus pneumoniae; Uracil; Virus Replication

1980
Partial elimination of G1 and G2 periods in higher plant cells by increasing the S period.
    Experimental cell research, 1983, Oct-15, Volume: 148, Issue:2

    Topics: Cell Cycle; Cells, Cultured; DNA Replication; Hydroxyurea; Interphase; Kinetics; Plant Physiological Phenomena; Uracil

1983
[Essential thrombocythemia in transformation from myelodysplastic syndrome to acute myeloid leukemia with inv(3) after treatment for gastric cancer].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2000, Volume: 41, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosome Inversion; Chromosomes, Human, Pair 3; Fatal Outcome; Gastrectomy; Humans; Hydroxyurea; Karyotyping; Leukemia, Myeloid, Acute; Male; Myelodysplastic Syndromes; Neoplasms, Second Primary; Stomach Neoplasms; Tegafur; Thrombocythemia, Essential; Uracil

2000
HYDROXYUREA: A SPECIFIC INHIBITOR OF DEOXYRIBONUCLEIC ACID SYNTHESIS.
    Biochimica et biophysica acta, 1965, Jan-11, Volume: 95

    Topics: Antineoplastic Agents; Carbon Isotopes; DNA; DNA Replication; DNA, Bacterial; Escherichia coli; Hydroxyurea; Metabolism; Pharmacology; Radiometry; Research; Thymidine; Tritium; Uracil

1965
Global analysis of functional surfaces of core histones with comprehensive point mutants.
    Genes to cells : devoted to molecular & cellular mechanisms, 2007, Volume: 12, Issue:1

    Topics: Amino Acid Sequence; Histones; Hydroxyurea; Methyl Methanesulfonate; Models, Molecular; Molecular Sequence Data; Mutagens; Nucleosomes; Phenotype; Point Mutation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Uracil

2007