hydroxyurea and tretinoin

hydroxyurea has been researched along with tretinoin in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19906 (17.65)18.7374
1990's8 (23.53)18.2507
2000's9 (26.47)29.6817
2010's9 (26.47)24.3611
2020's2 (5.88)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Comaish, JS; Hodge, L1
Baker, H1
Hoffbrand, AV; Porfiri, E; Wickremasinghe, RG1
Andersen, J; Bennett, JM; Boros, L; Cassileth, P; Kramer, ZB; Oken, M; Wiernik, PH1
Guernsey, DL; Yen, A1
Delaisse, JM; Eeckhout, Y; Vaes, G1
Fishbaugh, J; Freeman, L; Yen, A1
Ishikura, H; Izumi, Y; Mochizuki, T; Okazaki, T; Sawada, H; Tashima, M; Uchino, H1
Adey, WR; Bournias-Vardiabasis, N; Haggren, W; Nguyen, P; Phillips, JL1
Chen, MC; Gau, JP; Hwang, WL; Young, JH1
Alvarez-Fernández, L; Dosil, M; Gómez-Márquez, J1
Cambier, N; Chomienne, C; Fenaux, P; Guerci, A; Menot, ML; Wattel, E1
Cabrera, R; Díez, JL; Fernández, MN; Llamas, P; Lozano, IF; Queipo de Llano, MP1
Ohnishi, K1
Dolan, ME; Haraf, DJ; Hsieh, YC; Humerickhouse, R; Kies, MS; List, M; Mittal, BB; Pelzer, H; Stenson, K; Sulzen, L; Vokes, EE; Weichselbaum, RR; Witt, ME1
Kamada, T; Kawabata, H; Makino, T; Suzuki, S; Takatsuka, Y; Takeuchi, S; Utsunomiya, A1
Feng, R; Jiang, ZJ; Liu, XL; Meng, FY; Yin, F; Zheng, WY; Zhou, SY1
Fisher, D; Méchali, M1
Cedrone, M; Chierichini, A; Diverio, D; Foà, R; Lo Coco, F; Mariani, G; Pasquini, L; Pelosi, E; Peschle, C; Riccioni, R; Rossini, A; Saulle, E; Testa, U; Vitale, A1
Burnett, AK; Goldstone, AH; Hills, RK; McMullin, MF; Milligan, D; Prentice, AG; Wheatley, K1
Coleman, MD; Hill, EJ; Prince, M; Woehrling, EK1
Iland, HJ; Seymour, JF; Wei, A1
DeSimone, J; Ibanez, V; Jagadeeswaran, R; Kouznetsova, T; Lavelle, D; Rivers, A; Ruiz, MA; Vaitkus, K1
Balleari, E; Bernal, T; Beyne-Rauzy, O; Bordessoule, D; Calabuig, M; Cametti, G; Campelo, MD; Cheze, S; Cony-Makhoul, P; Dreyfus, F; Fenaux, P; Fensterl, J; Ferrero, D; Gaidano, G; Germing, U; Gioia, D; Götze, K; Guerci-Bresler, A; Hamel, JF; Kaivers, J; Kelaidi, C; Komrokji, R; Kotsianidis, I; Müller-Thomas, C; Pane, F; Park, S; Ramos, F; Roboz, GJ; Rose, C; Sanna, A; Santini, V; Sanz, GF; Sapena, R; Sekeres, MA; Stamatoullas, A; Steensma, DP; Thépot, S; Toma, A; Vey, N; Wattel, E1
Bruserud, Ø; Fredly, HK; Gjertsen, BT; Grønningsæter, IS; Hatfield, KJ1
Guan, Z; Li, S; Liang, Y; Niu, B; Wang, J; Wang, X; Yang, A; Yu, J; Zhu, Z1
Borghetto, V; Costanzo, E; Di Bella, G; Di Bella, L; Moscato, I1

Reviews

5 review(s) available for hydroxyurea and tretinoin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Psoriasis: current concepts in management.
    Drugs, 1977, Volume: 13, Issue:4

    Topics: Administration, Topical; Adrenal Cortex Hormones; Age Factors; Anthralin; Ficusin; Glycogen; Hair; Humans; Hydroxyurea; Methotrexate; Mitosis; Mucous Membrane; Nails; Psoriasis; Skin; Tars; Tretinoin; Ultraviolet Therapy

1977
Psoriasis: a review. II.
    Dermatologica, 1975, Volume: 150, Issue:3

    Topics: Adrenal Cortex Hormones; Anthralin; Azathioprine; Azauridine; Fluorouracil; Humans; Hydroxyurea; Lomustine; Mechlorethamine; Methotrexate; Psoriasis; Tars; Tretinoin; Ultraviolet Therapy

1975
[Oral antitumor drugs for hematological malignancies].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:3

    Topics: Administration, Oral; Antineoplastic Agents; Cytarabine; Etoposide; Hematologic Neoplasms; Humans; Hydroxyurea; Leukemia-Lymphoma, Adult T-Cell; Piperazines; Prodrugs; Tretinoin

1999
Have all-trans retinoic acid and arsenic trioxide replaced all-trans retinoic acid and anthracyclines in APL as standard of care.
    Best practice & research. Clinical haematology, 2014, Volume: 27, Issue:1

    Topics: Adult; Age Factors; Aged; Anthracyclines; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Blood Coagulation Factors; Clinical Trials as Topic; Combined Modality Therapy; Cytarabine; Etoposide; Humans; Hydroxyurea; Idarubicin; Leukemia, Promyelocytic, Acute; Maintenance Chemotherapy; Middle Aged; Mitoxantrone; Multicenter Studies as Topic; Oxides; Platelet Transfusion; Practice Guidelines as Topic; Remission Induction; Risk Assessment; Thioguanine; Treatment Outcome; Tretinoin

2014

Trials

4 trial(s) available for hydroxyurea and tretinoin

ArticleYear
13-cis-retinoic acid in the treatment of elderly patients with acute myeloid leukemia. A phase II pilot study of the Eastern Cooperative Oncology Group.
    Cancer, 1991, Mar-15, Volume: 67, Issue:6

    Topics: Aged; Aged, 80 and over; Drug Evaluation; Humans; Hydroxyurea; Leukemia, Myeloid; Leukocyte Count; Pilot Projects; Survival Rate; Tretinoin

1991
All-trans retinoic acid in adult chronic myelomonocytic leukemia: results of a pilot study.
    Leukemia, 1996, Volume: 10, Issue:7

    Topics: Aged; Antineoplastic Agents; Bone Marrow; Colony-Forming Units Assay; Female; Hematopoietic Stem Cells; Humans; Hydroxyurea; Leukemia, Myelomonocytic, Chronic; Leukocytosis; Male; Middle Aged; Pilot Projects; Platelet Count; Syndrome; Tretinoin; Tumor Cells, Cultured

1996
Concomitant chemoradiotherapy as primary therapy for locoregionally advanced head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease Progression; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Interferon alpha-2; Interferon-alpha; Male; Quality of Life; Radiotherapy; Radiotherapy Dosage; Recombinant Proteins; Survival Rate; Tretinoin

2000
A comparison of low-dose cytarabine and hydroxyurea with or without all-trans retinoic acid for acute myeloid leukemia and high-risk myelodysplastic syndrome in patients not considered fit for intensive treatment.
    Cancer, 2007, Mar-15, Volume: 109, Issue:6

    Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Middle Aged; Myelodysplastic Syndromes; Risk; Survival; Treatment Outcome; Tretinoin

2007

Other Studies

25 other study(ies) available for hydroxyurea and tretinoin

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Retinoic acid-induced granulocytic differentiation of HL60 human promyelocytic leukemia cells is preceded by downregulation of autonomous generation of inositol lipid-derived second messengers.
    Blood, 1991, Aug-15, Volume: 78, Issue:4

    Topics: Aluminum; Calcium Radioisotopes; Cell Differentiation; Cell Division; Diglycerides; Fluorine; Granulocytes; Humans; Hydrolysis; Hydroxyurea; Immunophenotyping; Inositol; Inositol Phosphates; Kinetics; Leukemia, Promyelocytic, Acute; Lipid Metabolism; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoric Diester Hydrolases; Second Messenger Systems; Tretinoin; Tumor Cells, Cultured

1991
Retinoic-acid-induced modulation of c-myc not dependent on its continued presence: possible role in pre-commitment for HL-60 cells.
    International journal of cancer, 1988, Oct-15, Volume: 42, Issue:4

    Topics: Cell Differentiation; Humans; Hydroxyurea; Leukemia, Promyelocytic, Acute; Proto-Oncogenes; RNA; Tretinoin; Tumor Cells, Cultured

1988
Bone-resorbing agents affect the production and distribution of procollagenase as well as the activity of collagenase in bone tissue.
    Endocrinology, 1988, Volume: 123, Issue:1

    Topics: Acetazolamide; Animals; Bone and Bones; Bone Resorption; Calcitonin; Calcitriol; Cells, Cultured; Collagenases; Cycloheximide; Dinoprostone; Enzyme Precursors; Fetus; Heparin; Hydroxyurea; Interleukin-1; Kinetics; Mice; Microbial Collagenase; Organophosphonates; Osteoclasts; Parathyroid Hormone; Prostaglandins E; Recombinant Proteins; Tretinoin; Triamcinolone; Tumor Necrosis Factor-alpha

1988
Hydroxyurea indices precommitment during retinoic induced HL-60 terminal myeloid differentiation: possible involvement of gene amplification.
    Leukemia research, 1987, Volume: 11, Issue:1

    Topics: Cell Differentiation; Cell Division; Cell Line; DNA; DNA Replication; Humans; Hydroxyurea; Interphase; Leukemia, Myeloid, Acute; Tretinoin

1987
Effect of antimetabolites and thymidine blockage on the induction of differentiation of HL-60 cells by retinoic acid or 1 alpha,25-dihydroxyvitamin D3.
    Experimental hematology, 1985, Volume: 13, Issue:10

    Topics: Antibiotics, Antineoplastic; Aphidicolin; Calcitriol; Cell Differentiation; Cell Division; Cell Line; Cytarabine; Diterpenes; DNA Replication; Humans; Hydroxyurea; Kinetics; Leukemia, Myeloid, Acute; Tretinoin

1985
Exposure of Drosophila melanogaster embryonic cell cultures to 60-Hz sinusoidal magnetic fields: assessment of potential teratogenic effects.
    Teratology, 1995, Volume: 51, Issue:4

    Topics: Animals; Cadmium; Cells, Cultured; Drosophila melanogaster; Electromagnetic Fields; Ganglia, Invertebrate; Hydroxyurea; Muscle Fibers, Skeletal; Teratogens; Tretinoin

1995
Treatment of acute promyelocytic leukemia with all-trans retinoic acid: successful control of hyperleukocytosis and leukostasis syndrome with leukaphereses and hydroxyurea.
    American journal of hematology, 1993, Volume: 43, Issue:4

    Topics: Administration, Oral; Adult; Female; Humans; Hydroxyurea; Leukapheresis; Leukemia, Promyelocytic, Acute; Leukocytosis; Stereoisomerism; Syndrome; Tretinoin

1993
Differentiation-linked expression of prothymosin alpha gene in human myeloid leukemic cells.
    Experimental cell research, 1993, Volume: 204, Issue:1

    Topics: Cell Differentiation; Down-Regulation; Humans; Hydroxyurea; Leukemia, Myeloid; Protein Precursors; RNA, Messenger; Tetradecanoylphorbol Acetate; Thymosin; Tretinoin; Tumor Cells, Cultured; Up-Regulation

1993
[Complete atrioventricular block associated with "retinoic acid syndrome": a previously undescribed association].
    Sangre, 1996, Volume: 41, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Heart Block; Humans; Hydroxyurea; Male; Tretinoin

1996
Successful treatment for leg ulcers due to hydroxyurea in a patient with chronic myelogenous leukaemia.
    Haematologia, 2002, Volume: 31, Issue:4

    Topics: Antineoplastic Agents; Debridement; Drug Combinations; Humans; Hydroxyurea; Leg Ulcer; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Ointments; Tretinoin; Vitamin E

2002
[All-trans retinoic acid for thromboembolic events in patients with M3 leukemia: a case report].
    Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 2003, Volume: 23, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Fatal Outcome; Humans; Hydroxyurea; Leukemia, Promyelocytic, Acute; Male; Thromboembolism; Tretinoin

2003
Vertebrate HoxB gene expression requires DNA replication.
    The EMBO journal, 2003, Jul-15, Volume: 22, Issue:14

    Topics: Animals; Cell Cycle; Cell Differentiation; DNA Replication; Embryo, Nonmammalian; Gene Expression Regulation, Developmental; Genes, Homeobox; Homeodomain Proteins; Hydroxyurea; Mice; Nucleic Acid Synthesis Inhibitors; Ovum; S Phase; Transcriptional Activation; Tretinoin; Tumor Cells, Cultured; Xenopus

2003
TRAIL decoy receptors mediate resistance of acute myeloid leukemia cells to TRAIL.
    Haematologica, 2005, Volume: 90, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 8; Cell Differentiation; Cell Membrane; Cytarabine; Drug Resistance, Neoplasm; Etoposide; Female; GPI-Linked Proteins; Granulocytes; HL-60 Cells; Humans; Hydroxyurea; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Monocytes; Oncogene Proteins, Fusion; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Member 10c; Recombinant Fusion Proteins; Tretinoin; Tumor Cells, Cultured; Tumor Necrosis Factor Decoy Receptors; Tumor Stem Cell Assay; U937 Cells

2005
Differentiating human NT2/D1 neurospheres as a versatile in vitro 3D model system for developmental neurotoxicity testing.
    Toxicology, 2008, Jul-30, Volume: 249, Issue:2-3

    Topics: Acrylamides; Blotting, Western; Cell Differentiation; Cell Line, Tumor; Cell Survival; Densitometry; Gene Expression; Humans; Hydroxyurea; Image Processing, Computer-Assisted; Immunohistochemistry; Lithium Chloride; Microscopy, Confocal; Models, Neurological; Nervous System Diseases; Neurons; Reverse Transcriptase Polymerase Chain Reaction; Teratogens; Tretinoin; Valproic Acid

2008
RN-1, a potent and selective lysine-specific demethylase 1 inhibitor, increases γ-globin expression, F reticulocytes, and F cells in a sickle cell disease mouse model.
    Experimental hematology, 2015, Volume: 43, Issue:7

    Topics: Anemia, Sickle Cell; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Inhibitors; Erythroid Precursor Cells; Erythropoiesis; Fetal Hemoglobin; gamma-Globins; Gene Expression Regulation; Hematopoietic Stem Cells; Histone Demethylases; Histones; Humans; Hydroxyurea; Methylation; Mice; Mice, Transgenic; Papio; Protein Processing, Post-Translational; Reticulocytes; Transgenes; Tranylcypromine; Tretinoin; U937 Cells

2015
Outcome of Lower-Risk Patients With Myelodysplastic Syndromes Without 5q Deletion After Failure of Erythropoiesis-Stimulating Agents.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, May-10, Volume: 35, Issue:14

    Topics: Aged; Aged, 80 and over; Anemia; Antilymphocyte Serum; Antineoplastic Agents; Arsenic; Azacitidine; Chromosome Deletion; Chromosomes, Human, Pair 5; Cyclosporine; Cytarabine; Decitabine; Disease Progression; Enzyme Inhibitors; Erythrocyte Transfusion; Female; Hematinics; Humans; Hydroxyurea; Immunologic Factors; Lenalidomide; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Recurrence; Retreatment; Retrospective Studies; Risk Factors; Survival Rate; Thalidomide; Treatment Failure; Tretinoin; Valproic Acid

2017
Systemic Metabolomic Profiling of Acute Myeloid Leukemia Patients before and During Disease-Stabilizing Treatment Based on All-Trans Retinoic Acid, Valproic Acid, and Low-Dose Chemotherapy.
    Cells, 2019, 10-10, Volume: 8, Issue:10

    Topics: Aged; Aged, 80 and over; Amino Acids; Cytarabine; Drug Therapy; Female; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Lipid Metabolism; Male; Mercaptopurine; Metabolomics; Middle Aged; Treatment Outcome; Tretinoin; Valproic Acid

2019
Unraveling the Mechanisms of Clinical Drugs-Induced Neural Tube Defects Based on Network Pharmacology and Molecular Docking Analysis.
    Neurochemical research, 2022, Volume: 47, Issue:12

    Topics: Animals; Anticonvulsants; Antineoplastic Agents; Class I Phosphatidylinositol 3-Kinases; ErbB Receptors; Female; Fluorouracil; Hydroxyurea; Methotrexate; Mice; Molecular Docking Simulation; Network Pharmacology; Neural Tube Defects; Phosphatidylinositol 3-Kinases; Pregnancy; Tretinoin; Valproic Acid

2022
A retrospective observational study on cases of osteosarcomas treated with a multitherapy: The rationale and effectiveness.
    Neuro endocrinology letters, 2022, Sep-16, Volume: 43, Issue:3

    Topics: Antioxidants; Bone Neoplasms; Butyric Acid; Humans; Hydroxyurea; Melatonin; Osteosarcoma; Tretinoin

2022