hydroxyurea and thiotepa

hydroxyurea has been researched along with thiotepa in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199012 (54.55)18.7374
1990's3 (13.64)18.2507
2000's4 (18.18)29.6817
2010's3 (13.64)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hansch, C; Khwaja, TA; Selassie, CD1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Kaidbey, KH1
Carter, SK; Wasserman, TH1
Rees, RB1
Armitage, JO; Bierman, PJ; Glenn, LD; Kessinger, A; Reed, EC; Vaughan, WP1
Chebotarev, AN; Golovina, ME; Smirnova, TD1
Pavone-Macaluso, M1
Israel, L1
Watne, AL1
Selawry, OS1
Covey, TH; Watne, AL1
Burns, BC; Rutledge, F; Smith, JP; Soffar, S1
Lo, TM; McCann, JJ; Webster, DA1
Hansson, K; Hartley-Asp, B1
Edwards, B; Kessinger, A; Reed, EC; Vaughan, WP1
Abraham, A; Cluster, A; Delgado, D; Hulbert, ML; Jacobsohn, D; Kukadiya, D; Murray, L; Shenoy, S1

Reviews

3 review(s) available for hydroxyurea and thiotepa

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Solid tumor chemotherapy: What have we to offer.
    American journal of surgery, 1970, Volume: 119, Issue:3

    Topics: Adult; Antineoplastic Agents; Child; Cyclophosphamide; Dactinomycin; Floxuridine; Fluorouracil; Humans; Hydroxyurea; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Palliative Care; Thiotepa; Time Factors; Vincristine

1970
Monochemotherapy of bronchogenic carcinoma withs special reference to cell type.
    Cancer chemotherapy reports. Part 3, 1973, Volume: 4, Issue:2

    Topics: Adenocarcinoma; Alkylating Agents; Antineoplastic Agents; Carcinoma, Bronchogenic; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Floxuridine; Humans; Hydroxyurea; Lung Neoplasms; Mechlorethamine; Methotrexate; Mitomycins; Nitrosourea Compounds; Plicamycin; Porfiromycin; Procarbazine; Streptonigrin; Thiotepa; Vinblastine

1973

Trials

1 trial(s) available for hydroxyurea and thiotepa

ArticleYear
Unrelated Umbilical Cord Blood Transplantation for Sickle Cell Disease Following Reduced-Intensity Conditioning: Results of a Phase I Trial.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2017, Volume: 23, Issue:9

    Topics: Alemtuzumab; Anemia, Sickle Cell; Calcineurin Inhibitors; Child; Child, Preschool; Cord Blood Stem Cell Transplantation; Female; Follow-Up Studies; Graft vs Host Disease; Humans; Hydroxyurea; Male; Melphalan; Mycophenolic Acid; Survival Analysis; Thiotepa; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Unrelated Donors; Vidarabine

2017

Other Studies

18 other study(ies) available for hydroxyurea and thiotepa

ArticleYear
Structure-activity relationships of antineoplastic agents in multidrug resistance.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:7

    Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured

1990
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Hair growth inhibition as a method of screening drugs for local antimitotic activity.
    The Journal of investigative dermatology, 1977, Volume: 68, Issue:2

    Topics: Animals; Antineoplastic Agents; Bleomycin; Colchicine; Cyclophosphamide; Cytarabine; Drug Evaluation, Preclinical; Fluorouracil; Guinea Pigs; Hair; Hydroxyurea; Injections, Intradermal; Mechlorethamine; Methotrexate; Mitosis; Thiotepa; Vincristine

1977
The chemotherapy of urologic cancer.
    Cancer, 1975, Volume: 36, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Alkylating Agents; Antineoplastic Agents; Doxorubicin; Drug Therapy, Combination; Estradiol; Female; Floxuridine; Fluorouracil; Humans; Hydroxyurea; Kidney Neoplasms; Male; Methotrexate; Middle Aged; Mitomycins; Plicamycin; Prostatic Neoplasms; Testicular Neoplasms; Thiotepa; Urinary Bladder Neoplasms; Urogenital Neoplasms; Vincristine

1975
Psoriasis: clinical aspects and management.
    Cutis, 1976, Volume: 18, Issue:2

    Topics: Administration, Topical; Age Factors; Azauridine; Fluorouracil; Humans; Hydroxyurea; Mechlorethamine; Methotrexate; Methoxsalen; Nitrosourea Compounds; Psoriasis; Thiotepa; Triamcinolone Acetonide

1976
High-dose hydroxyurea in autologous bone marrow transplantation: a promising "new" agent.
    Seminars in oncology, 1992, Volume: 19, Issue:3 Suppl 9

    Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms; Carmustine; Chemotherapy, Adjuvant; Cyclophosphamide; Drug Administration Schedule; Etoposide; Humans; Hydroxyurea; Lymphoma, Non-Hodgkin; Middle Aged; Remission Induction; Survival Rate; Thiotepa

1992
[Simultaneous estimation of sister chromatid exchange and evaluation of cell cycle delay].
    Biulleten' eksperimental'noi biologii i meditsiny, 1988, Volume: 105, Issue:5

    Topics: Animals; Caffeine; Cell Cycle; Cells, Cultured; Cricetinae; Cricetulus; Cytarabine; Hydroxyurea; Mitosis; Sister Chromatid Exchange; Thiotepa

1988
Chemotherapy of vesical and prostatic tumours.
    British journal of urology, 1971, Volume: 43, Issue:6

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Cobalt Isotopes; Cystitis; Daunorubicin; Ethoglucid; Fluorouracil; Humans; Hydroxyurea; Male; Methotrexate; Mitomycins; Nitrogen Mustard Compounds; Papilloma; Prostatic Neoplasms; Thiotepa; Urinary Bladder Neoplasms

1971
[Palliative chemotherapy of bronchial cancers. Current status of the problem].
    Le Poumon et le coeur, 1973, Volume: 29, Issue:6

    Topics: Antineoplastic Agents; Bleomycin; Bronchial Neoplasms; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Therapy, Combination; Emetine; Fluorouracil; Humans; Hydroxyurea; Methotrexate; Mitomycins; Mustard Compounds; Palliative Care; Procarbazine; Thiotepa; Vinblastine

1973
Hormones, chemotherapy, and the breast cancer patient.
    Oncology, 1972, Volume: 26, Issue:2

    Topics: Administration, Oral; Adrenalectomy; Adult; Aged; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Hydroxyurea; Injections, Intravenous; Menstruation; Middle Aged; Mitomycins; Neoplasm Recurrence, Local; Thiotepa

1972
Systemic chemotherapy for carcinoma of the cervix.
    American journal of obstetrics and gynecology, 1967, Mar-15, Volume: 97, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Cyclophosphamide; Female; Fluorouracil; Humans; Hydroxyurea; Mechlorethamine; Melphalan; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Progestins; Thiotepa; Urea; Uterine Cervical Neoplasms

1967
Cross-linking of DNA by alkylating agents and effects on DNA function in the chick embryo.
    Cancer research, 1971, Volume: 31, Issue:11

    Topics: Animals; Chick Embryo; Depression, Chemical; DNA; Hydroxyurea; Leucine; Mechlorethamine; Mitomycins; Nucleic Acid Denaturation; Protein Biosynthesis; RNA; Thiotepa; Thymidine; Tritium; Uridine

1971
Potentiation by hydroxyurea in G2-prophase of thiotepa- and bleomycin-induced chromosomal aberrations in Chinese hamster cells.
    Hereditas, 1981, Volume: 94, Issue:1

    Topics: Animals; Bleomycin; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; Drug Synergism; Hydroxyurea; Lung; Prophase; Thiotepa

1981
High-dose cyclophosphamide, thiotepa and hydroxyurea with autologous hematopoietic stem cell rescue: an effective consolidation chemotherapy regimen for early metastatic breast cancer.
    Bone marrow transplantation, 1994, Volume: 13, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Hematopoietic Stem Cell Transplantation; Humans; Hydroxyurea; Middle Aged; Neoplasm Metastasis; Thiotepa; Transplantation, Autologous

1994