hydroxyurea has been researched along with thiazoles in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.57) | 18.7374 |
| 1990's | 6 (21.43) | 18.2507 |
| 2000's | 8 (28.57) | 29.6817 |
| 2010's | 13 (46.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Greco, MN; Hageman, WE; Persico, FJ; Powell, ET; Tighe, JJ | 1 |
| Bonna, RL; Burns, ER; Elliot, GT; Kelly, KF; Wardlaw, TR | 1 |
| Falgueyret, JP; Hutchinson, JH; Riendeau, D | 1 |
| Carlson, RP; Gray, WB; Grimes, D; Hartman, DA; Howell, RE; Jenkins, LP; Kreft, AF; Kubrak, D | 1 |
| Carlson, RP; Glaser, K; Grimes, D; Gunawan, I; Hartman, DA; Howell, R; Kanzelberger, M; Malamas, MS; Nelson, JA; Shah, U | 1 |
| Rainsford, KD; Smith, F; Ying, C | 1 |
| Bloom, K; Irazoqui, JE; Lew, DJ; Theesfeld, CL | 1 |
| Hirasawa, N; Kushihara, M; Ohuchi, K; Takahagi, H; Takasaki, W; Takayanagi, M; Yamashita, M | 1 |
| Harada, K; Inoue, T; Nagakura, N; Oketani, K | 1 |
| Brezak, MC; Bugler, B; Ducommun, B; Galera-Contour, MO; Lemaire, M; Mondesert, O; Prevost, G | 1 |
| Bramanti, S; Fabio, G; Fantini, NN; Greco, I; Lambertenghi-Deliliers, G; Radaelli, F | 1 |
| Beutel, BA; Camp, HS; Frevert, EU; Gu, YG; Keyes, RF; Li, Q; Sham, HL; Wang, R; Wang, X; Weitzberg, M; Xu, X; Zhang, X | 1 |
| Cortes, J; Fava, C; Kantarjian, H; Verma, D | 1 |
| Berger, W; Dornetshuber, R; Heffeter, P; Hoda, MA; Jungwirth, U; Kiss, R; Mijatovic, T | 1 |
| Floride, E; Foller, M; Gu, S; Kucherenko, Y; Lang, F; Laufer, S; Luik, S; Mahmud, H; Wang, K | 1 |
| Borowiec, AS; Capiod, T; Delcourt, P; Dewailly, E; El Boustany, C; Katsogiannou, M; Prevarskaya, N | 1 |
| Hamšíková, E; Humlová, Z; Janatková, I; Klamová, H; Králíková, P; Malíčková, K; Roth, Z; Sterzl, I; Vonka, V | 1 |
| Alfonso, G; Alú, MF; Belli, C; Bianchini, M; Larripa, I | 1 |
| Pardanani, A | 1 |
| Guilhot, F; Roy, L; Tomowiak, C | 1 |
| Bergeron, A; Bergot, E; Bourdin, A; Bouvaist, H; Canuet, M; Girerd, B; Guignabert, C; Günther, S; Humbert, M; Jaïs, X; Macro, M; Montani, D; Natali, D; O'Callaghan, DS; Perros, F; Pison, C; Poubeau, P; Savale, L; Simonneau, G; Sitbon, O; Tubert-Bitter, P; Zalcman, G | 1 |
| Gaur, S; Horne, D; Hu, S; Hu, W; Smith, DL; Su, L; Synold, TW; Wu, J; Yen, Y; Yip, ML; Yuan, YC; Zhou, B | 1 |
| Duek, A; Grisouard, J; Hao-Shen, H; Jeandidier, E; Karow, A; Looser, R; Lundberg, P; Ojeda-Uribe, M; Skoda, RC | 1 |
| Bengió, RM; Bianchini, M; Ferri, CA; Gonzalez, MS; Larripa, IB; Moiraghi, EB; Noriega, MF | 1 |
| Dreimane, A; Ehrencrona, H; Gedde-Dahl, T; Gjertsen, BT; Hjorth-Hansen, H; Höglund, M; Koskenvesa, P; Lotfi, K; Majeed, W; Markevärn, B; Mustjoki, S; Ohm, L; Olsson-Strömberg, U; Porkka, K; Remes, K; Richter, J; Simonsson, B; Söderlund, S; Stenke, L; Suominen, M | 1 |
| Matsumura, I | 1 |
| Endo, A; Lamond, AI; Ly, T | 1 |
| Lavie, M; Rottenstreich, A; Rottenstreich, M | 1 |
1 review(s) available for hydroxyurea and thiazoles
| Article | Year |
|---|---|
[Treatment of chronic myeloid leukemia in chronic phase].
Topics: Allografts; Benzamides; Busulfan; Chromosomes, Human, Pair 22; Chromosomes, Human, Pair 9; Dasatinib; Drug Design; Fusion Proteins, bcr-abl; Hematopoietic Stem Cell Transplantation; Humans; Hydroxyurea; Imatinib Mesylate; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Molecular Targeted Therapy; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Randomized Controlled Trials as Topic; Thiazoles; Translocation, Genetic | 2014 |
1 trial(s) available for hydroxyurea and thiazoles
| Article | Year |
|---|---|
Dasatinib induces fast and deep responses in newly diagnosed chronic myeloid leukaemia patients in chronic phase: clinical results from a randomised phase-2 study (NordCML006).
Topics: Adult; Aged; Antineoplastic Agents; Benzamides; Dasatinib; Drug Administration Schedule; Female; Follow-Up Studies; Fusion Proteins, bcr-abl; Gene Expression; Humans; Hydroxyurea; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Remission Induction; Risk; Survival Analysis; Thiazoles | 2015 |
26 other study(ies) available for hydroxyurea and thiazoles
| Article | Year |
|---|---|
Benzothiazole hydroxy ureas as inhibitors of 5-lipoxygenase: use of the hydroxyurea moiety as a replacement for hydroxamic acid.
Topics: Animals; Benzothiazoles; Calcimycin; Dogs; Humans; Hydroxamic Acids; Hydroxyurea; Leukocytes; Leukotriene B4; Lipoxygenase Inhibitors; Methemoglobin; Mice; Molecular Structure; Peritonitis; SRS-A; Structure-Activity Relationship; Thiazoles | 1992 |
In vitro antiproliferative activity of 2'-(2-hydroxyphenyl)-2'-thiazoline-4'-carboxylic acid and its methyl ester on L1210 and P388 murine neoplasms.
Topics: Animals; Cell Cycle; Cell Division; Depression, Chemical; Hydroxyurea; Imides; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Mice; Thiazoles; Tumor Cells, Cultured | 1988 |
Criteria for the identification of non-redox inhibitors of 5-lipoxygenase.
Topics: Arachidonate 5-Lipoxygenase; Benzeneacetamides; Benzofurans; Enzyme Inhibitors; Humans; Hydroxamic Acids; Hydroxyurea; Indoles; Leukotrienes; Lipid Peroxides; Lipoxygenase Inhibitors; Naphthalenes; Oxidation-Reduction; Thiazoles | 1993 |
Pulmonary pharmacology of WAY-126299A: a dual-acting 5-lipoxygenase inhibitor and leukotriene D4 antagonist.
Topics: Acetamides; Anesthesia; Animals; Benzothiazoles; Bronchoconstriction; Guinea Pigs; Humans; Hydroxyurea; In Vitro Techniques; Leukotriene D4; Lipoxygenase Inhibitors; Lung; Naphthaleneacetic Acids; Quinolines; Respiration, Artificial; Thiazoles | 1995 |
Azole phenoxy hydroxyureas as selective and orally active inhibitors of 5-lipoxygenase.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Bronchoconstriction; Guinea Pigs; Humans; Hydroxyurea; Leukotriene B4; Lipoxygenase Inhibitors; Macrophages; Mice; Molecular Structure; Monocytes; Oxazoles; Rats; Structure-Activity Relationship; Thiazoles | 1996 |
Effects of 5-lipoxygenase inhibitors on interleukin production by human synovial tissues in organ culture: comparison with interleukin-1-synthesis inhibitors.
Topics: Animals; Benzofurans; Enzyme-Linked Immunosorbent Assay; Hip Joint; Humans; Hydroxyurea; Indoles; Interleukin-1; Knee Joint; Lipoxygenase Inhibitors; Naphthalenes; Organ Culture Techniques; Oxindoles; Pyrazoles; Quinolines; Structure-Activity Relationship; Swine; Synovial Membrane; Tarsus, Animal; Thiazoles; Thiophenes | 1996 |
The role of actin in spindle orientation changes during the Saccharomyces cerevisiae cell cycle.
Topics: Actins; Anaphase; Bridged Bicyclo Compounds, Heterocyclic; Calcium-Binding Proteins; CDC28 Protein Kinase, S cerevisiae; Cell Cycle; Cell Cycle Proteins; Cell Polarity; Cyclin B; Dyneins; Fungal Proteins; Genes, Fungal; Hydroxyurea; Microfilament Proteins; Microtubules; Mutation; Nocodazole; Nuclear Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Spindle Apparatus; Temperature; Thiazoles; Thiazolidines; Tropomyosin | 1999 |
Inhibition by troglitazone of the antigen-induced production of leukotrienes in immunoglobulin E-sensitized RBL-2H3 cells.
Topics: Animals; Antigens; Arachidonic Acid; Calcimycin; Cell Degranulation; Cell Line; Chromans; Culture Media, Conditioned; Hydroxyurea; Hypoglycemic Agents; Immunoglobulin E; Leukotriene B4; Leukotriene C4; Leukotriene E4; Leukotrienes; Lipoxygenase Inhibitors; Male; Mast Cells; Neutrophils; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidinediones; Troglitazone | 2000 |
In vitro effects of E3040, a dual inhibitor of 5-lipoxygenase and thromboxane A(2) synthetase, on eicosanoid production.
Topics: Animals; Arachidonate 5-Lipoxygenase; Benzothiazoles; Dinoprostone; Dose-Response Relationship, Drug; Eicosanoids; Humans; Hydroxyurea; Indomethacin; Leukocytes; Leukotriene B4; Lipoxygenase Inhibitors; Male; Mesalamine; Methacrylates; Neutrophils; Peritoneal Cavity; Prostaglandin-Endoperoxide Synthases; Pyridines; Rats; Rats, Inbred F344; Sheep; Sulfasalazine; Thiazoles; Thromboxane B2; Thromboxane-A Synthase | 2001 |
A fission yeast strain expressing human CDC25A phosphatase: a tool for selectivity studies of pharmacological inhibitors of CDC25.
Topics: Benzothiazoles; cdc25 Phosphatases; Cell Cycle Proteins; Cell Proliferation; DNA; DNA Damage; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Enzyme Inhibitors; Fungal Proteins; Genotype; Humans; Hydroxyurea; Infrared Rays; Inhibitory Concentration 50; Mitosis; Models, Genetic; Phosphoric Monoester Hydrolases; Plasmids; Protein Isoforms; ras-GRF1; Schizosaccharomyces; Temperature; Thiazoles; Time Factors; Ultraviolet Rays | 2004 |
Dasatinib-related alveolar pneumonia responsive to corticosteroids.
Topics: Adrenal Cortex Hormones; Dasatinib; Humans; Hydroxyurea; Lung; Male; Middle Aged; Pleural Effusion; Pneumonia; Protein Kinase Inhibitors; Pulmonary Alveoli; Pyrimidines; Remission Induction; Steroids; Thiazoles; Tomography, X-Ray Computed; Treatment Outcome | 2006 |
The synthesis and structure-activity relationship studies of selective acetyl-CoA carboxylase inhibitors containing 4-(thiazol-5-yl)but-3-yn-2-amino motif: polar region modifications.
Topics: Acetyl-CoA Carboxylase; Alkynes; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydroxyurea; Isoxazoles; Molecular Conformation; Recombinant Proteins; Structure-Activity Relationship; Thiazoles | 2007 |
Complexity of BCR-ABL kinase domain mutations during the course of therapy with tyrosine kinase inhibitors in chronic myeloid leukemia.
Topics: Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Benzamides; Dasatinib; Drug Resistance, Neoplasm; Female; Fusion Proteins, bcr-abl; Harringtonines; Homoharringtonine; Humans; Hydroxyurea; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Mutagenesis; Mutation, Missense; Piperazines; Point Mutation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Pyrimidines; Thiazoles; Treatment Failure | 2009 |
The Na+/K+-ATPase is the Achilles heel of multi-drug-resistant cancer cells.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cardenolides; Cell Line, Tumor; Cell Survival; Drug Resistance, Multiple; HeLa Cells; Humans; Hydroxyurea; Ligands; Neoplasms; Sodium-Potassium-Exchanging ATPase; Thiazoles | 2009 |
Participation of leukotriene C(4) in the regulation of suicidal erythrocyte death.
Topics: Blotting, Western; Calcium; Caspase 3; Caspase 8; Cell Culture Techniques; Cell Death; Cell Size; Cells, Cultured; Erythrocyte Membrane; Erythrocytes; Glucose; Humans; Hydroxyurea; Leukotriene C4; Microscopy, Confocal; Phosphatidylserines; Receptors, Leukotriene; Thiazoles | 2009 |
Differential roles of STIM1, STIM2 and Orai1 in the control of cell proliferation and SOCE amplitude in HEK293 cells.
Topics: Calcium Channels; CDC2 Protein Kinase; Cell Adhesion Molecules; Cell Line; Cell Proliferation; Humans; Hydroxyurea; Membrane Proteins; Neoplasm Proteins; Nucleic Acid Synthesis Inhibitors; ORAI1 Protein; Patch-Clamp Techniques; Quinolines; Receptor, Muscarinic M3; RNA, Small Interfering; Stromal Interaction Molecule 1; Stromal Interaction Molecule 2; Thiazoles; Transfection; TRPC Cation Channels | 2010 |
Changes of immunological profiles in patients with chronic myeloid leukemia in the course of treatment.
Topics: Adult; Antineoplastic Agents; Benzamides; C-Reactive Protein; Complement System Proteins; Dasatinib; Female; Humans; Hydroxyurea; Imatinib Mesylate; Immunity, Innate; Immunoglobulins; Immunologic Factors; Interferon-alpha; Interleukin-6; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Longitudinal Studies; Male; Middle Aged; Piperazines; Protein Kinase Inhibitors; Pyrimidines; T-Lymphocytes; Thiazoles; Treatment Outcome | 2010 |
Novel variant Ph translocation t(9;22;11)(q34;q11.2;p15)inv(9)(p13q34) in chronic myeloid leukemia involving a one-step mechanism.
Topics: Aged; Antineoplastic Agents; Benzamides; Chromosome Banding; Chromosome Inversion; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 22; Chromosomes, Human, Pair 9; Dasatinib; Female; Humans; Hydroxyurea; Imatinib Mesylate; In Situ Hybridization, Fluorescence; Interferon-gamma; Karyotyping; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Metaphase; Philadelphia Chromosome; Piperazines; Pyrimidines; Thiazoles; Translocation, Genetic | 2011 |
Systemic mastocytosis in adults: 2011 update on diagnosis, risk stratification, and management.
Topics: Adult; Antineoplastic Agents; Benzamides; Bone Marrow; Cladribine; Dasatinib; Disease-Free Survival; Humans; Hydroxyurea; Imatinib Mesylate; Interferon Type I; Mast Cells; Mastocytosis, Systemic; Piperazines; Point Mutation; Proto-Oncogene Proteins c-kit; Pyrimidines; Recombinant Proteins; Risk; Staurosporine; Thiazoles | 2011 |
Blood consult: high Sokal risk chronic myeloid leukemia and suboptimal response.
Topics: Antineoplastic Agents; Benzamides; Dasatinib; Humans; Hydroxyurea; Imatinib Mesylate; Leukemia, Myeloid, Chronic-Phase; Male; Middle Aged; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Risk Factors; Thiazoles | 2011 |
Pulmonary arterial hypertension in patients treated by dasatinib.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Antineoplastic Agents; Benzamides; Bone Morphogenetic Protein Receptors, Type II; Calcium Channel Blockers; Dasatinib; Drug Utilization; Endothelin Receptor Antagonists; Female; Follow-Up Studies; Hemodynamics; Humans; Hydroxyurea; Hypertension, Pulmonary; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Registries; Thiazoles; Treatment Outcome | 2012 |
A small-molecule blocking ribonucleotide reductase holoenzyme formation inhibits cancer cell growth and overcomes drug resistance.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Benzamides; Blotting, Western; Cell Cycle; Cell Proliferation; Chromatography, High Pressure Liquid; Computer Simulation; Deoxycytidine; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Flow Cytometry; Gemcitabine; Half-Life; Humans; Hydroxyurea; Interleukin-2 Receptor alpha Subunit; Mice; Mice, Inbred NOD; Mice, SCID; Mutagenesis, Site-Directed; Mutation; Neoplasms; Protein Conformation; Ribonucleotide Reductases; Small Molecule Libraries; Structure-Activity Relationship; Surface Plasmon Resonance; Tandem Mass Spectrometry; Thiazoles | 2013 |
Complex subclone structure that responds differentially to therapy in a patient with essential thrombocythemia and chronic myeloid leukemia.
Topics: Clone Cells; Dasatinib; Female; Genes, abl; Humans; Hydroxyurea; Janus Kinase 2; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Middle Aged; Point Mutation; Pyrimidines; Thiazoles; Thrombocythemia, Essential; Translocation, Genetic | 2013 |
Clinical activity of ponatinib in one patient with chronic myeloid leukemia in chronic phase with e19a2 transcript and T315I mutation.
Topics: Antineoplastic Agents; Dasatinib; Drug Resistance, Neoplasm; Female; Fusion Proteins, bcr-abl; Gene Expression; Humans; Hydroxyurea; Imidazoles; Leukemia, Myeloid, Chronic-Phase; Middle Aged; Mutation; Pyridazines; Pyrimidines; RNA, Messenger; Thiazoles; Treatment Outcome | 2015 |
Proteomic analysis of the response to cell cycle arrests in human myeloid leukemia cells.
Topics: Cell Cycle Checkpoints; Cell Line, Tumor; Chromatin Assembly and Disassembly; Culture Media, Serum-Free; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Proteomics; Quinolines; Signal Transduction; Thiazoles | 2015 |
[CHRONIC MYELOID LEUKEMIA IN A YOUNG MALE PRESENTING WITH BILATERAL CALF PAIN DUE TO LEUKOSTASIS].
Topics: Allopurinol; Bone Marrow Examination; Dasatinib; Diagnosis, Differential; Enzyme Inhibitors; Humans; Hydroxyurea; Leg; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukocyte Count; Leukostasis; Male; Myalgia; Ophthalmoscopy; Philadelphia Chromosome; Pyrimidines; Retinal Hemorrhage; Thiazoles; Treatment Outcome; Young Adult | 2015 |