Compounds > hydroxyurea

hydroxyurea and tenofovir

hydroxyurea has been researched along with tenofovir in 14 studies

Research

Studies (14)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (21.43)	18.2507
2000's	5 (35.71)	29.6817
2010's	4 (28.57)	24.3611
2020's	2 (14.29)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Merigan, TC; Palmer, S; Shafer, RW	1
Anton, KE; Cherrington, JM; Lamy, PD; Margot, NA; Miller, MD; Mulato, AS; Quan, Y; Salomon, H; Wainberg, MA	1
Crabbs, C; Greenhouse, J; Lewis, MG; Lisziewicz, J; Lori, F; Silvera, P; Tinelli, C; Varga, G; Wagner, W; Xu, J; Yalley-Ogunro, J; Zinn, DE	1
Barditch-Crovo, P; Coakley, DF; Collier, A; Deeks, SG; McGowan, I; Miller, M; Smith, A	1
Kast, RE	1
Perricone, G; Pungolino, E; Vinci, M	1
Adil, N; Asmari, M; Khan, F; Kumari, S; Musharraf, SG; Siddiqui, AJ; Uddin, J	1

Reviews

1 review(s) available for hydroxyurea and tenofovir

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

2 trial(s) available for hydroxyurea and tenofovir

Article	Year
PMPA trials recruiting. AIDS treatment news, 1998, Sep-18, Issue:303 Topics: Adenine; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV Infections; Humans; Hydroxyurea; Organophosphonates; Organophosphorus Compounds; Tenofovir; Viral Load	1998
Hydroxyurea does not enhance the anti-HIV activity of low-dose tenofovir disoproxil fumarate. Journal of acquired immune deficiency syndromes (1999), 2001, Dec-01, Volume: 28, Issue:4 Topics: Adenine; Adult; Anti-HIV Agents; Cohort Studies; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Hydroxyurea; Male; Organophosphonates; Organophosphorus Compounds; Tenofovir	2001

Other Studies

11 other study(ies) available for hydroxyurea and tenofovir

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
Hydroxyurea enhances the activities of didanosine, 9-[2-(phosphonylmethoxy)ethyl]adenine, and 9-[2-(phosphonylmethoxy)propyl]adenine against drug-susceptible and drug-resistant human immunodeficiency virus isolates. Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:8 Topics: Adenine; Anti-HIV Agents; Antineoplastic Agents; Didanosine; DNA, Viral; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; Humans; Hydroxyurea; Inhibitory Concentration 50; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Tenofovir; Thymidine	1999
In vitro selection and characterization of HIV-1 with reduced susceptibility to PMPA. Antiviral therapy, 1999, Volume: 4, Issue:2 Topics: Adenine; Anti-HIV Agents; Drug Resistance; HIV Reverse Transcriptase; HIV-1; Hydroxyurea; Mutation; Organophosphonates; Organophosphorus Compounds; Tenofovir	1999
Control of SIV rebound through structured treatment interruptions during early infection. Science (New York, N.Y.), 2000, Nov-24, Volume: 290, Issue:5496 Topics: Adenine; Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Didanosine; Drug Administration Schedule; Hydroxyurea; Lymphocyte Activation; Macaca mulatta; Organophosphonates; Organophosphorus Compounds; Random Allocation; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Tenofovir; Viral Load; Viremia; Virus Replication	2000
Tenofovir, COX inhibitors and zileuton during cancer immunotherapies: up-regulated TNF-alpha increases antigen driven lymphocyte proliferation. Molecular immunology, 2003, Volume: 40, Issue:5 Topics: Adenine; Adenylyl Cyclases; Anti-HIV Agents; Cell Division; Cyclooxygenase Inhibitors; Humans; Hydroxyurea; Immunotherapy; Lipoxygenase Inhibitors; Lymphocytes; Neoplasms; Organophosphonates; Organophosphorus Compounds; Tenofovir; Tumor Necrosis Factor-alpha; Up-Regulation	2003
Occult hepatitis B infection reactivation after ruxolitinib therapy. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2017, Volume: 49, Issue:6 Topics: Aged; Antiviral Agents; Drug Resistance; Enzyme Inhibitors; Guanine; Hepatitis B, Chronic; Humans; Hydroxyurea; Janus Kinase Inhibitors; Male; Middle Aged; Nitriles; Polycythemia Vera; Primary Myelofibrosis; Pyrazoles; Pyrimidines; Tenofovir; Virus Activation	2017
Metabolomics Study of Serum Samples of β-YAC Transgenic Mice Treated with Tenofovir Disoproxil Fumarate. International journal of molecular sciences, 2022, Dec-12, Volume: 23, Issue:24 Topics: Animals; beta-Thalassemia; Fetal Hemoglobin; Hydroxyurea; Metabolomics; Mice; Mice, Transgenic; Tenofovir	2022