hydroxyurea has been researched along with sirolimus in 19 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 4 (21.05) | 18.2507 |
2000's | 2 (10.53) | 29.6817 |
2010's | 11 (57.89) | 24.3611 |
2020's | 2 (10.53) | 2.80 |
Authors | Studies |
---|---|
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Dumont, FJ; Fischer, P; Sirotina, A | 1 |
Fabbro, D; Ferrari, S; Frost, V; Mercep, L; Meyer, T; Morley, SJ | 1 |
Buchkovich, KJ; Greider, CW | 1 |
Branellec, D; Le Roux, A; Perlman, H; Sata, M; Sedlak, TW; Walsh, K | 1 |
Ansari, AA; Bostik, P; Greenberg, KP; Mayne, AE; Powell, JD; Villinger, F | 1 |
Boehm, A; Herndlhofer, S; Jaeger, U; Knoebl, P; Mayerhofer, M; Sillaber, C; Sperr, WR; Valent, P | 1 |
Jarosz, DF; Lindquist, S | 1 |
Duan, Y; Feng, J; Jiang, L; Zhao, Y | 1 |
Ann, DK; Chen, L; Chen, W; Chen, YR; Hu, S; Kuo, ML; Tang, M; Yang, L; Yen, Y; Zhang, K; Zhang, L; Zhou, B | 1 |
Calzolari, R; Di Marzo, R; Maggio, A; Martorana, A; Pecoraro, A; Rigano, P; Sacco, M; Scazzone, C; Troia, A | 1 |
Fujimuro, M; Ito, A; Nakagawa, K; Nakata, S; Takeda, H; Watanabe, T | 1 |
Borgmann, K; Koalick, D; Ludwig, K; Pai, GM; Pospiech, H; Rubio, I; Wang, ZQ; Zielinski, A | 1 |
Al-Khatti, AA; Alkhunaizi, AM | 1 |
Barré, B; González, A; Hall, MN; Li, J; Liti, G; Long, A; Mustonen, V; Persson, K; Vázquez-García, I; Warringer, J; Yue, JX | 1 |
Cui, W; Hull, L; Li, X; Xiao, M | 1 |
Chaudhury, I; Holz, MK; Knudson, K; Nolan, M | 1 |
Li, J; Liti, G; Mikhalev, E; Stenberg, S; Thompson, D; Warringer, J; Yue, JX | 1 |
1 review(s) available for hydroxyurea and sirolimus
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for hydroxyurea and sirolimus
Article | Year |
---|---|
Evaluation of in vivo antineoplastic effects of rapamycin in patients with chemotherapy-refractory AML.
Topics: Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Pilot Projects; Sirolimus; Treatment Outcome | 2009 |
17 other study(ies) available for hydroxyurea and sirolimus
Article | Year |
---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Increased LFA-1-mediated homotypic cell adhesion is associated with the G1 growth arrest induced by rapamycin in a T cell lymphoma.
Topics: Animals; Antibodies; CD11 Antigens; CD18 Antigens; Cell Adhesion; Cell Cycle; Cell Division; Cell Line; Culture Media, Serum-Free; Flow Cytometry; G1 Phase; Hydroxyurea; Immunosuppressive Agents; Lymphocyte Function-Associated Antigen-1; Lymphoma, T-Cell; Mimosine; Nocodazole; Polyenes; Sirolimus; Tacrolimus; Tumor Cells, Cultured | 1995 |
The phosphodiesterase inhibitor SQ 20006 selectively blocks mitogen activation of p70S6k and transition to S phase of the cell division cycle without affecting the steady state phosphorylation of eIF-4E.
Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Cell Division; Cell Line; Cyclic AMP; Emetine; Enzyme Activation; Eukaryotic Initiation Factor-4E; Humans; Hydroxyurea; Immunosuppressive Agents; Kinetics; Mice; Mitogen-Activated Protein Kinase 1; Mitogens; Nicotinic Acids; Peptide Initiation Factors; Phosphodiesterase Inhibitors; Phosphorylation; Polyenes; Polyribosomes; Protein Biosynthesis; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Reticulocytes; Ribosomal Protein S6 Kinases; S Phase; Sirolimus | 1995 |
Telomerase regulation during entry into the cell cycle in normal human T cells.
Topics: Antibodies; Antigens, CD20; B-Lymphocytes; Blotting, Northern; CD2 Antigens; CD28 Antigens; CDC2-CDC28 Kinases; Cell Cycle; Cell Cycle Proteins; Cells, Cultured; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; Enzyme Inhibitors; Humans; Hydroxyurea; Immunosuppressive Agents; Interleukin-2; Leukocytes; Microtubule-Associated Proteins; Phytohemagglutinins; Polyenes; Polymerase Chain Reaction; Protein Serine-Threonine Kinases; Receptor-CD3 Complex, Antigen, T-Cell; RNA; Sirolimus; T-Lymphocytes; Telomerase; Tumor Suppressor Proteins; Up-Regulation | 1996 |
Bax-mediated cell death by the Gax homeoprotein requires mitogen activation but is independent of cell cycle activity.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cell Cycle; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; G1 Phase; Homeodomain Proteins; Hydroxyurea; Male; Mice; Mitogens; Muscle Proteins; Muscle, Smooth, Vascular; Phenotype; Polyenes; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; S Phase; Serum Albumin, Bovine; Sirolimus; Tumor Suppressor Protein p53 | 1998 |
Relative resistance in the development of T cell anergy in CD4+ T cells from simian immunodeficiency virus disease-resistant sooty mangabeys.
Topics: Adult; Animals; Base Sequence; CD4-Positive T-Lymphocytes; Cells, Cultured; Cercocebus atys; Clonal Anergy; Cyclosporine; Cytokines; Epitopes, T-Lymphocyte; Humans; Hydroxyurea; Immunity, Innate; Kinetics; Lymphocyte Activation; Macaca mulatta; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Muromonab-CD3; Simian Acquired Immunodeficiency Syndrome; Sirolimus | 2001 |
Hsp90 and environmental stress transform the adaptive value of natural genetic variation.
Topics: Adaptation, Physiological; Biological Evolution; Crosses, Genetic; Deoxycholic Acid; Drug Resistance, Fungal; Genetic Variation; HSP90 Heat-Shock Proteins; Hydroxyurea; Intracellular Signaling Peptides and Proteins; Microtubule-Associated Proteins; Mitochondrial Proteins; Open Reading Frames; Polymorphism, Genetic; Protein Serine-Threonine Kinases; Quantitative Trait Loci; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sirolimus; Stress, Physiological; Sulfurtransferases | 2010 |
Genetic interactions between protein phosphatases CaPtc2p and CaPph3p in response to genotoxins and rapamycin in Candida albicans.
Topics: Antifungal Agents; Candida albicans; Cloning, Molecular; DNA Damage; DNA, Fungal; Epistasis, Genetic; Fungal Proteins; Gene Deletion; Hydroxyurea; Methyl Methanesulfonate; Mutagens; Phenotype; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2C; Protein Serine-Threonine Kinases; Signal Transduction; Sirolimus | 2013 |
Reciprocal regulation of autophagy and dNTP pools in human cancer cells.
Topics: Animals; Autophagy; Gene Knockdown Techniques; Humans; Hydroxyurea; Intracellular Space; Mice, Inbred NOD; Mice, SCID; Neoplasms; Nucleotides; Ribonucleoside Diphosphate Reductase; RNA, Small Interfering; Signal Transduction; Sirolimus; Xenograft Model Antitumor Assays | 2014 |
Efficacy of Rapamycin as Inducer of Hb F in Primary Erythroid Cultures from Sickle Cell Disease and β-Thalassemia Patients.
Topics: Adolescent; Adult; Aged; alpha-Globins; Anemia, Sickle Cell; beta-Globins; beta-Thalassemia; Cells, Cultured; Erythroid Precursor Cells; Female; Fetal Hemoglobin; gamma-Globins; Gene Expression Regulation; Genotype; Humans; Hydroxyurea; Male; Middle Aged; Mutation; Sirolimus; Young Adult | 2015 |
The dynamics of histone H2A ubiquitination in HeLa cells exposed to rapamycin, ethanol, hydroxyurea, ER stress, heat shock and DNA damage.
Topics: Acetylation; DNA Damage; Endoplasmic Reticulum Stress; Ethanol; Heat-Shock Response; HeLa Cells; Histones; Humans; Hydrogen Peroxide; Hydroxyurea; Methyl Methanesulfonate; Sirolimus; Subcellular Fractions; Ubiquitinated Proteins; Ubiquitination | 2016 |
TSC loss distorts DNA replication programme and sensitises cells to genotoxic stress.
Topics: Animals; Cell Cycle; Cell Death; Cells, Cultured; Chromosome Aberrations; DNA Damage; DNA Replication; Dose-Response Relationship, Drug; Doxorubicin; Fibroblasts; Genomic Instability; Hydroxyurea; Mice, Knockout; RNA Interference; Sirolimus; Time Factors; TOR Serine-Threonine Kinases; Transfection; Tuberous Sclerosis Complex 1 Protein; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2016 |
Additive effect of sirolimus and hydroxycarbamide on fetal haemoglobin level in kidney transplant patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Female; Fetal Hemoglobin; Humans; Hydroxyurea; Kidney Transplantation; Male; Middle Aged; Sirolimus | 2019 |
Shared Molecular Targets Confer Resistance over Short and Long Evolutionary Timescales.
Topics: Biological Evolution; Cell Cycle Proteins; Drug Resistance, Fungal; Hydroxyurea; Mutation; Phosphatidylinositol 3-Kinases; Quantitative Trait Loci; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Selection, Genetic; Sirolimus | 2019 |
GATA-type transcription factors play a vital role in radiation sensitivity of Cryptococcus neoformans by regulating the gene expression of specific amino acid permeases.
Topics: Amino Acid Transport Systems; Cryptococcus neoformans; Fluconazole; Fungal Proteins; GATA Transcription Factors; Gene Expression Regulation, Fungal; Gene Library; Hydroxyurea; Mutation; Phylogeny; Radiation Tolerance; Sirolimus | 2019 |
Fanconi anemia and mTOR pathways functionally interact during stalled replication fork recovery.
Topics: Aphidicolin; Cell Survival; DNA; DNA Repair; DNA Replication; Fanconi Anemia; Fanconi Anemia Complementation Group D2 Protein; Fibroblasts; Genome, Human; Genomic Instability; Humans; Hydroxyurea; Mitomycin; Primary Cell Culture; Protein Binding; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases | 2021 |
Genome instability footprint under rapamycin and hydroxyurea treatments.
Topics: DNA, Ribosomal; Genomic Instability; Humans; Hydroxyurea; Mutation; Saccharomyces cerevisiae; Sirolimus | 2023 |