hydroxyurea has been researched along with phenobarbital in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (35.71) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 5 (35.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Madison, RM; Viguera, C; Ward, JM; Weisburger, EK; Weisburger, JH | 1 |
| Rabes, HM | 1 |
| Abakumova, OIu; Kutsenko, NG; Lerman, MI; Podobed, OV | 1 |
| Chang, KS; Shires, TK | 1 |
| Mori, H; Okumura, A; Tanaka, T | 1 |
| Gupta, C; Yaffe, SJ | 1 |
1 review(s) available for hydroxyurea and phenobarbital
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
13 other study(ies) available for hydroxyurea and phenobarbital
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Modification of diethylnitrosamine liver carcinogenesis with phenobarbital but not with immunosuppression.
Topics: Animals; Antilymphocyte Serum; Carcinoma, Hepatocellular; Diethylnitrosamine; Hydroxyurea; Immunosuppression Therapy; Liver Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Phenobarbital; Rats; Time Factors | 1975 |
Kinetics of hepatocellular proliferation as a function of the microvascular structure and functional state of the liver.
Topics: Allyl Compounds; Animals; Cell Compartmentation; Cell Cycle; Cell Division; DNA; Hydroxyurea; Liver; Liver Regeneration; Microcirculation; Phenobarbital; Rats | 1977 |
[Accelerated microsomal DNA synthesis under the influence of xenobiotics and chemical carcinogens].
Topics: Animals; Benzopyrenes; Caffeine; Cell Nucleus; Cycloheximide; DNA; DNA, Mitochondrial; DNA, Neoplasm; Hydroxyurea; Liver Neoplasms, Experimental; Male; Methylnitrosourea; Mice; Mice, Inbred Strains; Microsomes, Liver; Phenobarbital; Puromycin; Stimulation, Chemical | 1979 |
Unscheduled DNA synthesis in rat liver after gastric administration of halothane.
Topics: Animals; Cell Nucleus; DNA; Halothane; Hydroxyurea; Intubation, Gastrointestinal; Liver; Male; Phenobarbital; Rats; Thymidine | 1982 |
Simultaneous measurement of unscheduled and replicating DNA synthesis by means of a new cell culture insert DNA retention method: rapid induction of replicating DNA synthesis in response to genotoxic carcinogens.
Topics: 2-Acetylaminofluorene; Aminobiphenyl Compounds; Animals; Autoradiography; Carcinogens; Cells, Cultured; Diethylnitrosamine; DNA; DNA Replication; Hydroxyurea; Liver; Male; Mutagens; Nafenopin; Phenobarbital; Rats; Scintillation Counting | 1996 |
Phenobarbital-induced alterations in the sexual differentiation of the female rat: reversal by hydroxyurea and cycloheximide.
Topics: Animals; Cycloheximide; Estrous Cycle; Female; Fertility; Hydroxyurea; Phenobarbital; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Sex Differentiation | 1982 |