hydroxyurea and nalidixic acid

hydroxyurea has been researched along with nalidixic acid in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199024 (75.00)18.7374
1990's0 (0.00)18.2507
2000's2 (6.25)29.6817
2010's6 (18.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Davies, J; Schindler, D1
Heinonen, J; Pekola, ML1
Blais, KD; Gomez, RF; Herrero, A; Sinskey, AJ1
Kogoma, T; Lark, KG1
Aldea, M; de la Campa, AG; Dopazo, A; Tormo, A; Vicente, M1
Denizeau, F; Jutras, D; Marion, M1
Cannon, G; Heinhorst, S; Weissbach, A1
Jones, PA; Liu, L; Nyce, J1
Blamire, J; Cohn, G; Lee, HL; McGowan, R1
Braly, P; Simpson, L1
Fogt, SM; Price, AR1
Morgan, C; Rosenkranz, HS; Zweig, M1
Lazdunski, A; Shapiro, BM; Siccardi, AG1
Ingram, LO; Thurston, EL; Van Baalen, C1
Fangman, WL; Hill, WE1
Barber, DS; Winder, FG1
Deering, RA; Kantor, GJ1
Medoff, G; Overholt, S1
Pasternak, J; Samoiloff, MR1
Jyssum, K1
Kumar, HD; Madan, V1
Bresnick, E; Eastman, A; Ireland, CM1
Clarkson, JM; Mitchell, DL1
García, E; López, R; Ronda, C1
Hiroishi, S; Maki, M; Okamoto, H; Yoshida, T1
Bates, D; Blinkova, A; Cambridge, J; Magnan, D; Walker, JR1

Reviews

2 review(s) available for hydroxyurea and nalidixic acid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Inhibitors of macromolecular synthesis in yeast.
    Methods in cell biology, 1975, Volume: 12

    Topics: Acriflavine; Amphotericin B; Anisomycin; Anti-Bacterial Agents; Antineoplastic Agents; Cycloheximide; Dactinomycin; Daunorubicin; Deoxyadenosines; Depression, Chemical; DNA; Ethidium; Fluorouracil; Fungal Proteins; Hydroxyurea; Mitomycins; Nalidixic Acid; Phenazines; Phenylethyl Alcohol; Porfiromycin; Puromycin; RNA; Saccharomyces cerevisiae; Streptonigrin; Sulfanilamides; Triaziquone; Trichothecenes; Uracil

1975

Other Studies

30 other study(ies) available for hydroxyurea and nalidixic acid

ArticleYear
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Inhibitors of DNA synthesis cause excessive DNA synthesis in dnaA mutants of Escherichia coli K12.
    Canadian journal of microbiology, 1978, Volume: 24, Issue:10

    Topics: DNA Replication; DNA, Bacterial; Escherichia coli; Hydroxyurea; Mutation; Nalidixic Acid; Temperature

1978
Effects of inhibitors of protein, RNA and DNA synthesis on heat-injured Salmonella typhimurium LT2.
    Journal of general microbiology, 1976, Volume: 97, Issue:1

    Topics: Bacterial Proteins; Chloramphenicol; DNA Repair; DNA, Bacterial; Hot Temperature; Hydroxyurea; Molecular Weight; Nalidixic Acid; Rifampin; RNA, Bacterial; Salmonella typhimurium

1976
Characterization of the replication of Escherichia coli DNA in the absence of protein synthesis: stable DNA replication.
    Journal of molecular biology, 1975, May-15, Volume: 94, Issue:2

    Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Proteins; Chloramphenicol; Cytarabine; DNA Replication; DNA, Bacterial; Escherichia coli; Hot Temperature; Hydroxyurea; Models, Biological; Mutation; Nalidixic Acid; Protein Biosynthesis; RNA, Bacterial; Thymine

1975
Coupling between DNA replication and cell division mediated by the FtsA protein in Escherichia coli: a pathway independent of the SOS response, the "TER" pathway.
    Journal of bacteriology, 1985, Volume: 164, Issue:2

    Topics: Bacterial Proteins; Cell Division; DNA Replication; DNA, Bacterial; Escherichia coli; Genes, Bacterial; Hydroxyurea; Mutation; Nalidixic Acid; RNA, Bacterial; Temperature

1985
The effects of putative DNA repair inhibitors on DNA adduct levels and unscheduled DNA synthesis in rat hepatocytes exposed to 2-acetylaminofluorene.
    Mutation research, 1989, Volume: 216, Issue:1

    Topics: 2-Acetylaminofluorene; Animals; Aphidicolin; Cells, Cultured; Cytarabine; Dideoxynucleosides; Diterpenes; DNA Damage; DNA Repair; Hydroxyurea; In Vitro Techniques; Liver; Male; Nalidixic Acid; Nucleic Acid Synthesis Inhibitors; Rats; Topoisomerase I Inhibitors

1989
Chloroplast DNA synthesis during the cell cycle in cultured cells of Nicotiana tabacum: inhibition by nalidixic acid and hydroxyurea.
    Archives of biochemistry and biophysics, 1985, Volume: 239, Issue:2

    Topics: Cell Cycle; Cells, Cultured; Chloroplasts; DNA Replication; DNA, Circular; Hydroxyurea; Nalidixic Acid; Nicotiana; Plants; Plants, Toxic; Ribonucleoside Diphosphate Reductase; Topoisomerase II Inhibitors

1985
Variable effects of DNA-synthesis inhibitors upon DNA methylation in mammalian cells.
    Nucleic acids research, 1986, May-27, Volume: 14, Issue:10

    Topics: Animals; Aphidicolin; Base Sequence; Cell Line; Chromatography, High Pressure Liquid; Cricetinae; Cycloheximide; Cytarabine; Dactinomycin; Diterpenes; DNA; DNA Polymerase II; DNA Replication; Fibrosarcoma; Hydroxyurea; Methylation; Nalidixic Acid; Novobiocin

1986
DNA metabolism during infection of Anacystis nidulans by cyanophage AS-1. VI. Effect of hydroxyurea and nalidixic acid on the development of cyanophage AS-1.
    Microbios, 1985, Volume: 43, Issue:176S

    Topics: Chlorophyll; Cyanobacteria; DNA; DNA, Viral; Hydroxyurea; Nalidixic Acid; Protein Biosynthesis; Viruses

1985
Synchronization of Leishmania tarentolae by hydroxyurea.
    The Journal of protozoology, 1970, Volume: 17, Issue:4

    Topics: Agar; Aminopterin; Animals; Cell Division; Culture Media; DNA; Hydroxyurea; Leishmania; Mitochondria; Nalidixic Acid; Nucleosides; Staining and Labeling; Thymidine; Time Factors; Tritium

1970
Effect of nalidixic acid on PBS2 bacteriophage infection of Bacillus subtilis.
    Journal of virology, 1973, Volume: 12, Issue:2

    Topics: Bacillus subtilis; Bacteriophages; Colorimetry; DNA, Bacterial; DNA, Viral; Hydroxyurea; Nalidixic Acid; Thymine; Time Factors; Uracil; Virus Replication

1973
Development of coliphage T5: ultrastructural and biochemical studies.
    Journal of virology, 1972, Volume: 9, Issue:3

    Topics: Bacteriolysis; Carbon Isotopes; Centrifugation, Density Gradient; Coliphages; Colorimetry; Cytidine; Cytoplasm; DNA Replication; DNA, Bacterial; DNA, Viral; Escherichia coli; Floxuridine; Hydroxyurea; Inclusion Bodies, Viral; Lysogeny; Microscopy, Electron; Mutation; Nalidixic Acid; Thymidine; Time Factors; Tritium; Viral Proteins; Virus Replication

1972
Interrelationship between membrane protein composition and deoxyribonucleic acid synthesis in Escherichia coli.
    Biochemistry, 1972, Apr-25, Volume: 11, Issue:9

    Topics: Amino Acids; Azo Compounds; Bacterial Proteins; Carbon Isotopes; Cell Membrane; DNA, Bacterial; Electrophoresis; Escherichia coli; Floxuridine; Genetics, Microbial; Hydroxyurea; Isotope Labeling; Leucine; Mitomycins; Mutation; Nalidixic Acid; Penicillins; Sodium Dodecyl Sulfate; Temperature; Thymine; Tritium; Uracil

1972
Effects of selected inhibitors on growth and cell division in Agmenellum.
    Archiv fur Mikrobiologie, 1972, Volume: 81, Issue:1

    Topics: Bacterial Proteins; Cell Division; Chloramphenicol; DNA, Bacterial; Escherichia coli; Eukaryota; Hydroxyurea; Microscopy, Electron; Microscopy, Phase-Contrast; Mutation; Nalidixic Acid; Penicillin G

1972
Single-strand breaks in deoxyribonucleic acid and viability loss during deoxyribonucleic acid synthesis inhibition in Escherichia coli.
    Journal of bacteriology, 1973, Volume: 116, Issue:3

    Topics: Adenine; Carbon Radioisotopes; Cell Survival; Chromosomes, Bacterial; DNA, Bacterial; DNA, Single-Stranded; Escherichia coli; Hydroxyurea; Molecular Weight; Mutation; Nalidixic Acid; Nucleic Acid Denaturation; Temperature; Thymidine; Tritium

1973
Effects of hydroxyurea, nalidixic acid and zinc limitation on DNA polymerase and ATP-dependent deoxyribonuclease activities of Mycobacterium smegmatis.
    Journal of general microbiology, 1973, Volume: 76, Issue:1

    Topics: Alcohol Oxidoreductases; Bacterial Proteins; Cell-Free System; Culture Media; Deoxyribonucleases; DNA Nucleotidyltransferases; DNA, Bacterial; Glycerol; Hydroxyurea; Iron; Mycobacterium; Nalidixic Acid; Phenanthrolines; Thymine Nucleotides; Tritium; Zinc

1973
Effect of nalidixic acid and hydroxyurea on division ability of Escherichia coli fil+ and lon- strains.
    Journal of bacteriology, 1968, Volume: 95, Issue:2

    Topics: Bacterial Proteins; Carbon Isotopes; Cell Division; DNA Replication; DNA, Bacterial; Escherichia coli; Hydroxyurea; Lactones; Nalidixic Acid; RNA, Bacterial; Thymidine; Tritium; Uracil

1968
Thymineless death in Escherichia coli 15T- and recombinants of 15T- and Escherichia coli K-12.
    Journal of bacteriology, 1970, Volume: 102, Issue:1

    Topics: Chromatography, Paper; Colicins; Coliphages; Culture Media; DNA; Escherichia coli; Filtration; Genetics, Microbial; Hydroxyurea; Microscopy, Electron; Mitomycins; Nalidixic Acid; Recombination, Genetic; Thymine; Transferases; Ultraviolet Rays

1970
The effect of growth inhibitors on postembryonic development in the free-living nematode, Pangrellus silusiae.
    Comparative biochemistry and physiology, 1970, Mar-01, Volume: 33, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Chloramphenicol; Cycloheximide; Dactinomycin; Depression, Chemical; DNA; Enzyme Inhibitors; Ethanol; Hydroxyurea; Leucine; Metabolism; Nalidixic Acid; Nematoda; Nucleic Acids; Protein Biosynthesis; Puromycin; RNA; Thymidine; Time Factors; Tritium; Uridine

1970
Influence of inhibitors of DNA and protein synthesis on the kinetics of DNA uptake in Neisseria meningitidis transformation.
    Acta pathologica et microbiologica Scandinavica, 1969, Volume: 77, Issue:3

    Topics: Arginine; Chloramphenicol; Cold Temperature; Cystine; Dinitrophenols; DNA; DNA Replication; Genetics, Microbial; Glycine; Histidine; Hydroxyurea; Kinetics; Molecular Biology; Nalidixic Acid; Neisseria meningitidis; Proline; Transformation, Genetic

1969
Action of nalidixic acid and hydroxyurea on two blue-green algae.
    Zeitschrift fur allgemeine Mikrobiologie, 1971, Volume: 11, Issue:6

    Topics: Cyanobacteria; Hydroxyurea; Mutagens; Nalidixic Acid

1971
The influence of inhibitors on the repair of benzo[a]pyrene-damaged DNA in hamster tracheal epithelial cells.
    Carcinogenesis, 1984, Volume: 5, Issue:2

    Topics: Animals; Benzamides; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Line; Clone Cells; Cricetinae; Cytarabine; DNA Repair; DNA Replication; Epithelium; Hydroxyurea; Kinetics; Nalidixic Acid; Novobiocin; Trachea

1984
The effect of various inhibitors of DNA synthesis on the repair of DNA photoproducts.
    Biochimica et biophysica acta, 1983, Sep-09, Volume: 740, Issue:4

    Topics: Animals; Aphidicolin; Cell Line; Cricetinae; Cricetulus; Cytarabine; Diterpenes; DNA; DNA Polymerase II; DNA Repair; DNA Replication; Female; Hydroxyurea; Kinetics; Nalidixic Acid; Novobiocin; Ovary; Ultraviolet Rays

1983
Selective replication of diplophage Dp-4 deoxyribonucleic acid in 6-(p-hydroxyphenylazo)-uracil treated Streptococcus pneumoniae.
    FEBS letters, 1980, Feb-25, Volume: 111, Issue:1

    Topics: Bacteriophages; DNA Replication; DNA, Bacterial; DNA, Viral; Floxuridine; Hydroxyphenylazouracil; Hydroxyurea; Kinetics; Nalidixic Acid; Streptococcus pneumoniae; Uracil; Virus Replication

1980
Coordination of DNA replication and cell division in cyanobacteria Microcystis aeruginosa.
    FEMS microbiology letters, 2005, Oct-01, Volume: 251, Issue:1

    Topics: Bacterial Proteins; Cell Division; Chromosomes, Bacterial; Colony Count, Microbial; Cytoskeletal Proteins; DNA Replication; Hydroxyurea; Microcystis; Nalidixic Acid; Nucleic Acid Synthesis Inhibitors; Transcription, Genetic

2005
A replication-inhibited unsegregated nucleoid at mid-cell blocks Z-ring formation and cell division independently of SOS and the SlmA nucleoid occlusion protein in Escherichia coli.
    Journal of bacteriology, 2014, Volume: 196, Issue:1

    Topics: Adenosine Triphosphatases; Bacterial Proteins; Carrier Proteins; Cell Cycle Proteins; Cell Division; Chromosomes, Bacterial; Cytoskeletal Proteins; DNA Replication; Escherichia coli; Escherichia coli Proteins; Hydroxyurea; Membrane Proteins; Nalidixic Acid; SOS Response, Genetics

2014