hydroxyurea and mocetinostat

hydroxyurea has been researched along with mocetinostat in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19905 (29.41)18.7374
1990's6 (35.29)18.2507
2000's2 (11.76)29.6817
2010's3 (17.65)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Aghai, E; Froom, P; Quitt, M1
George, LW; Kagonyera, GM; Munn, R1
Kwiatkowska, J; Malec, J; Przybyszewski, WM; Sitarska, E; Szczepańnska, I1
Goldblum, SE; Jay, M; Wu, KM1
Bacon, PE; Cory, JG; Sato, A1
Camerini, R; Caputi, AP; Graziani, P; Squadrito, F; Zingarelli, B1
Alarcón de la Lastra, C; Luque, MI; Martín, MJ; Motilva, V1
Broutman, L; Callaghan, C; Doria, MI; Eiznhamer, D; Keshavarzian, A; Zarif, A1
Kotadia, B; Mangino, JE; Mangino, MJ; Sielczak, M1
Bell, RL; Carter, GW; Harris, RR; Wilcox, D1
Duits, AJ; Hillen, HF; Saleh, AW1
Britti, D; Chatterjee, PK; Cuzzocrea, S; Di Paola, R; Patel, NS; Sautebin, L; Thiemermann, C1
King, SB1
Chen, CM; Jin, CD; Shi, SS; Tu, XK; Wang, CH; Wen, S; Yang, WZ; Yang, YK; Zhang, YL1
Chatterjee, D; Ember, E; Nayak, KA; van Eldik, R1
Barbu, EA; Dominical, VM; Mendelsohn, L; Thein, SL1

Reviews

1 review(s) available for hydroxyurea and mocetinostat

ArticleYear
Nitric oxide production from hydroxyurea.
    Free radical biology & medicine, 2004, Sep-15, Volume: 37, Issue:6

    Topics: Anemia, Sickle Cell; Free Radicals; Hemoglobins; Humans; Hydroxylamine; Hydroxyurea; Iron; Models, Chemical; Nitrates; Nitric Oxide; Nitrites; Oxygen; Peroxidase; Time Factors; Urease

2004

Trials

1 trial(s) available for hydroxyurea and mocetinostat

ArticleYear
Levels of endothelial, neutrophil and platelet-specific factors in sickle cell anemia patients during hydroxyurea therapy.
    Acta haematologica, 1999, Volume: 102, Issue:1

    Topics: Adolescent; Adult; Aged; Anemia, Sickle Cell; Antisickling Agents; Blood Platelets; Endothelium, Vascular; Female; Fibronectins; Humans; Hydroxyurea; Interleukin-8; L-Selectin; Male; Middle Aged; Neutrophils; Peroxidase; Receptors, Interleukin-6; Solubility; Vascular Cell Adhesion Molecule-1; von Willebrand Factor

1999

Other Studies

15 other study(ies) available for hydroxyurea and mocetinostat

ArticleYear
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
The mean leukocyte myeloperoxidase index in hematological patients.
    American journal of clinical pathology, 1989, Volume: 92, Issue:6

    Topics: Hematologic Diseases; Hospitalization; Humans; Hydroxyurea; Leukocytes; Lymphoma; Lymphoma, Non-Hodgkin; Peroxidase; Recurrence; Reference Values

1989
Light and electron microscopic changes in corneas of healthy and immunomodulated calves infected with Moraxella bovis.
    American journal of veterinary research, 1988, Volume: 49, Issue:3

    Topics: Animals; Cattle; Cattle Diseases; Cornea; Dexamethasone; Hydroxyurea; Immunity; Immunosuppression Therapy; Keratoconjunctivitis, Infectious; Leukocyte Count; Leukocytes; Microbial Collagenase; Microscopy, Electron; Microscopy, Electron, Scanning; Moraxella; Neutrophils; Peroxidase; Random Allocation; Tears

1988
Amelioration of hydroxyurea-induced suppression of phagocytosis in human granulocytes by free radical scavengers.
    Scandinavian journal of haematology, 1985, Volume: 34, Issue:1

    Topics: Antioxidants; Ascorbic Acid; Aspirin; Benzoates; Benzoic Acid; Catalase; Depression, Chemical; Free Radicals; Granulocytes; Humans; Hydroxyurea; Isoenzymes; Peroxidase; Peroxidases; Phagocytosis; Superoxide Dismutase; Vitamin E

1985
Lung myeloperoxidase as a measure of pulmonary leukostasis in rabbits.
    Journal of applied physiology (Bethesda, Md. : 1985), 1985, Volume: 59, Issue:6

    Topics: Animals; Cyclophosphamide; Granulocytes; Hydroxyurea; Lung; Lung Diseases; Peroxidase; Rabbits; Respiratory Distress Syndrome; Sonication; Streptococcus pneumoniae; Time Factors

1985
Studies on the differential mechanisms of inhibition of ribonucleotide reductase by specific inhibitors of the non-heme iron subunit.
    Advances in enzyme regulation, 1984, Volume: 22

    Topics: Anaerobiosis; Animals; Catalase; Cell Division; Cells, Cultured; Deferoxamine; Guanazole; Humans; Hydroxyurea; Isoenzymes; Isoquinolines; Leukemia L1210; Peroxidase; Peroxidases; Pyrazoles; Quinolines; Ribonucleoside Diphosphate Reductase; Ribonucleotide Reductases; Triazoles

1984
Effects of zileuton, a new 5-lipoxygenase inhibitor, in experimentally induced colitis in rats.
    Agents and actions, 1993, Volume: 39, Issue:3-4

    Topics: Animals; Colitis; Colon; Eicosanoids; Hydroxyurea; Inflammatory Bowel Diseases; Leukocytes; Lipoxygenase Inhibitors; Male; Peroxidase; Rats; Rats, Wistar; Sulfasalazine; Trinitrobenzenesulfonic Acid

1993
Role of polymorphonuclear leukocytes and oxygen-derived free radicals in chronic gastric lesion induced by acetic acid in rat.
    General pharmacology, 1996, Volume: 27, Issue:3

    Topics: Acetic Acid; Allopurinol; Animals; Antimetabolites; Capillary Permeability; Enzyme Inhibitors; Epithelium; Female; Hydroxyurea; Male; Neutrophils; Peroxidase; Rats; Rats, Wistar; Reactive Oxygen Species; Stomach Ulcer

1996
The effect of a selective 5-lipoxygenase inhibitor, zileuton, on tissue damage in acute colonic inflammation in rats.
    Inflammation, 1996, Volume: 20, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Hydroxyurea; Intestinal Mucosa; Leukocyte Count; Leukotriene B4; Lipoxygenase Inhibitors; Male; Mitomycin; Neutrophils; Peroxidase; Rats; Rats, Sprague-Dawley

1996
Effects of the 5-lipoxygenase inhibitor A-64077 on intestinal hypothermic organ preservation injury.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 281, Issue:2

    Topics: Animals; Cryopreservation; Dinoprostone; Dogs; Hydroxyurea; Ileum; Leukotriene B4; Lipoxygenase Inhibitors; Organ Preservation; Peroxidase

1997
The role of tissue mast cells in polyacrylamide gel-induced inflammation in mice.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1998, Volume: 47, Issue:3

    Topics: Acrylic Resins; Animals; Anti-Inflammatory Agents; Dinoprostone; Hydroxyurea; Inflammation; Leukocyte Count; Leukotriene B4; Lipoxygenase Inhibitors; Mast Cells; Mice; Mice, Inbred BALB C; Neutrophils; Peroxidase

1998
Reduction of renal ischemia-reperfusion injury in 5-lipoxygenase knockout mice and by the 5-lipoxygenase inhibitor zileuton.
    Molecular pharmacology, 2004, Volume: 66, Issue:2

    Topics: Animals; Arachidonate 5-Lipoxygenase; Disease Models, Animal; Hydroxyurea; Inflammation; Intercellular Adhesion Molecule-1; Ischemia; Kidney Diseases; Leukotriene B4; Lipoxygenase Inhibitors; Mice; Mice, Knockout; Neutrophils; Peroxidase; Reperfusion Injury

2004
Zileuton reduces inflammatory reaction and brain damage following permanent cerebral ischemia in rats.
    Inflammation, 2010, Volume: 33, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Brain; Brain Ischemia; Cerebral Infarction; Disease Models, Animal; Encephalitis; Enzyme-Linked Immunosorbent Assay; Hydroxyurea; Immunohistochemistry; Interleukin-1beta; Lipid Peroxidation; Lipoxygenase Inhibitors; Male; Malondialdehyde; Neuroprotective Agents; Neutrophil Infiltration; Nitric Oxide; Nitric Oxide Synthase Type II; Peroxidase; Rats; Rats, Sprague-Dawley; Time Factors; Transcription Factor RelA; Tumor Necrosis Factor-alpha

2010
[Ru(III)(edta)(H(2)O)](-) mediated oxidation of hydroxyurea with H(2)O(2). Kinetic and mechanistic investigation.
    Dalton transactions (Cambridge, England : 2003), 2010, Feb-21, Volume: 39, Issue:7

    Topics: Catalase; Catalysis; Hydrogen Peroxide; Hydroxyurea; Kinetics; Oxidation-Reduction; Peroxidase; Ruthenium

2010
Neutrophils remain detrimentally active in hydroxyurea-treated patients with sickle cell disease.
    PloS one, 2019, Volume: 14, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Sickle Cell; Antisickling Agents; Case-Control Studies; Cell Degranulation; Cells, Cultured; Extracellular Traps; Female; Humans; Hydroxyurea; Male; Middle Aged; Neutrophils; Peroxidase; Primary Cell Culture; Young Adult

2019