hydroxyurea has been researched along with mitomycin in 48 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 17 (35.42) | 18.7374 |
1990's | 10 (20.83) | 18.2507 |
2000's | 9 (18.75) | 29.6817 |
2010's | 10 (20.83) | 24.3611 |
2020's | 2 (4.17) | 2.80 |
Authors | Studies |
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Hansch, C; Khwaja, TA; Selassie, CD | 1 |
Dias, CB; Hansch, C; Khwaja, TA; Pentecost, S; Selassie, CD | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Rossman, TG; Wolosin, D | 1 |
Apostolidis, T; Daniilidis, J; Fountzilas, G; Kalogera-Fountzila, A; Tourkantonis, A; Vritsios, A | 1 |
Anastasakis, C; Daniilidis, J; Delis, V; Fountzilas, G; Haritanti, A; Nicolaou, A; Sideras, T; Sridhar, K; Vritsios, A | 1 |
Cortés, F; Mateos, S; Ortiz, T; Piñero, J | 1 |
Portnoĭ, AS | 1 |
Sakaguchi, K; Sono, A | 1 |
Oikawa, A; Tohda, H | 1 |
Booker, R; Truman, JW | 1 |
Calissano, P; Coccia, EM; Di Luzio, A; Improta, T; Romeo, G; Salvatore, AM | 1 |
Bartlett, GL; Howell, LE; Kreider, JW | 1 |
Albert, DA; Bluestein, HG | 1 |
Filetti, S; Rapoport, B; Seto, P | 1 |
Böhmer, RM | 1 |
De Salvia, R; Degrassi, F; Fiore, M; Palitti, F; Tanzarella, C | 2 |
De Vecchis, L; Lagomarsino Caprino, MC; Mazzei, T; Periti, P; Popoli, P | 1 |
Dardick, I; Dubsky, M; Kiss, G; Setterfield, G; Sheinin, R | 1 |
Kozuka, H; Miyahara, T; Sakaguchi, M; Yamada, H | 1 |
Dubinina, LG | 1 |
Broutman, L; Callaghan, C; Doria, MI; Eiznhamer, D; Keshavarzian, A; Zarif, A | 1 |
Carnevale, A; Frias, S; Gómez, L; Molina, B; Ostrosky-Wegman, P; Rojas, E | 1 |
Conaway, HH; Grigorie, D; Lerner, UH | 1 |
Bagby, GC; Bakke, AC; Brown, MG; Grompe, M; Heinrich, MC; Hoatlin, ME; Keeble, WW; Magenis, RE; Olson, SB; Reifsteck, CA; Silvey, KV; Zhi, Y; Zigler, AJ | 1 |
Johnstone, P; Kohler, S; Moses, RE; Olson, S; Reifsteck, C; Worland, P | 1 |
Aksu, G; Bagci, G; Duranoglu, Y; Lüleci, G; Oztürk, A; Yücel, I | 1 |
Eifel, PJ | 1 |
Boimel, P; Darby, K; Greger, JG; Katz, RA; Rall, GF; Skalka, AM | 1 |
Barber, LJ; Carr, AM; Hartley, JA; Lambert, S; Mason, SJ; McHugh, PJ; Pearce, JA | 1 |
Fukuhara, K; Jenssen, D; Johansson, F; Lundin, C; Matsuoka, A; Onfelt, A; Sahlin, M; Sjöberg, BM | 1 |
Garriott, ML; Hoffman, WP; Lee, C; Murphy, GP; Phelps, JB | 1 |
Bissler, JJ; Dixon, K; Lu, L; Robison, JG | 1 |
Adang, LA; Kremer, BE; Macara, IG | 1 |
Acuña, H; Coleman, MA; Frias, S; Gómez, L; Hinz, JM; Jones, IM; Martinez, A; Molina, B | 1 |
Moore, DH | 1 |
Escudero, B; Franco, S; Gesheva, S; Huso, DL; Liu, G; Orsburn, B; Prakash, M | 1 |
Cigliano, RA; Mittelsten Scheid, O; Rosa, M; Schlögelhofer, P; Von Harder, M | 1 |
Kusakabe, T; Lee, JM; Mon, H; Shiotsuki, T; Sugahara, R | 1 |
Beveridge, RD; Boulton, SJ; Collis, SJ; Maslen, S; Myers, KN; Patil, AA; Skehel, JM; Staples, CJ | 1 |
Altamirano-Lozano, M; Carnevale, A; Frias, S; Gómez, L; Marchetti, F; Molina, B; Ortiz, R; Ramos, S; Torres, L | 1 |
Gu, S; Jin, L; Ma, J; Ni, X; Pan, Q; Wang, J; Xu, M; Zhen, N; Zhu, J | 1 |
Chen, Y; Guo, Z; Hua, Y; Shen, B; Shi, R; Tian, B; Truong, K; Wang, L; Xu, H; Xu, X; Zhao, Y; Zheng, L; Zhou, M | 1 |
Gao, Y; Hua, Y; Mao, S; Shi, R; Song, S; Tian, B; Wang, L; Wang, Y; Xiao, Y; Xu, H; Xu, X; Zhao, Y | 1 |
Chaudhury, I; Holz, MK; Knudson, K; Nolan, M | 1 |
4 review(s) available for hydroxyurea and mitomycin
Article | Year |
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DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Chemotherapy of prostatic cancer].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Dacarbazine; Diethylstilbestrol; Doxorubicin; Estramustine; Fluorouracil; Humans; Hydroxyurea; Male; Melphalan; Methotrexate; Mitomycin; Mitomycins; Prednisolone; Procarbazine; Prostatic Neoplasms; Streptozocin; Vincristine | 1985 |
Chemoradiation for carcinoma of the cervix: advances and opportunities.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Hysterectomy; Lung Neoplasms; Mitomycin; Prospective Studies; Radiation Tolerance; Radiation-Sensitizing Agents; Randomized Controlled Trials as Topic; Survival Rate; Treatment Outcome; Uterine Cervical Neoplasms; Vincristine | 2000 |
Combined chemotherapy and radiation therapy for cervical cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials, Phase III as Topic; Combined Modality Therapy; Female; Fluorouracil; Humans; Hydroxyurea; Mitomycin; Nitroimidazoles; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms | 2004 |
2 trial(s) available for hydroxyurea and mitomycin
Article | Year |
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Induction chemotherapy with cisplatinum, 5-fluorouracil, bleomycin, mitomycin C and hydroxyurea for previously untreated locally advanced squamous cell carcinomas of the head and neck.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Mitomycin; Mitomycins; Neck Dissection; Neoplasm Staging | 1989 |
Preliminary research on the evaluation of some prognostic factors in a randomized study of adjuvant immunochemotherapy in colorectal adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Colonic Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Humans; Hydroxyurea; Male; Middle Aged; Mitomycin; Mitomycins; Prognosis; Rectal Neoplasms; Semustine | 1984 |
42 other study(ies) available for hydroxyurea and mitomycin
Article | Year |
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Structure-activity relationships of antineoplastic agents in multidrug resistance.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured | 1990 |
Comparative structure-activity relationships of antifolate triazines inhibiting murine tumor cells sensitive and resistant to methotrexate.
Topics: Animals; Chemical Phenomena; Chemistry, Physical; Chickens; Drug Resistance; Folic Acid Antagonists; Humans; Leukemia L5178; Leukemia, Experimental; Mathematics; Methotrexate; Mice; Structure-Activity Relationship; Triazines | 1984 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Differential susceptibility to carcinogen-induced amplification of SV40 and dhfr sequences in SV40-transformed human keratinocytes.
Topics: Aphidicolin; Carcinogens; Cell Line, Transformed; Cell Transformation, Viral; Cycloheximide; Drug Resistance; Gene Amplification; Genes, Viral; Humans; Hydroxyurea; Keratinocytes; Methotrexate; Mitomycin; Proto-Oncogene Mas; Simian virus 40; Tetrahydrofolate Dehydrogenase; Time Factors; Ultraviolet Rays; X-Rays | 1992 |
[Combined therapy of locally advanced squamous epithelial cancers in the area of the head and neck].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Mitomycin; Mitomycins | 1988 |
G2 effects of DNA-repair inhibitors on chromatid-type aberrations in root-tip cells treated with maleic hydrazide and mitomycin C.
Topics: Caffeine; Cell Cycle; Chromosome Aberrations; Chromosomes; Cytarabine; DNA Damage; DNA Repair; Floxuridine; Hydroxyurea; In Vitro Techniques; Interphase; Maleic Hydrazide; Mitomycin; Mitomycins; Plants; Pyridazines; Thymidine | 1989 |
The influence of a protein synthesis inhibitor on sister-chromatid exchange in the plant Vicia faba.
Topics: Chromosome Aberrations; Cycloheximide; DNA Replication; Fabaceae; Hydroxyurea; Mitomycin; Mitomycins; Plant Proteins; Plants, Medicinal; Sister Chromatid Exchange | 1986 |
Proliferation-dependent reduction of sister-chromatid exchange frequency induced by mitomycin C in human lymphoblastoid cells and its suppression by inhibitors of DNA replication.
Topics: 4-Nitroquinoline-1-oxide; Cell Division; Cycloheximide; Cytarabine; Depression, Chemical; DNA Repair; DNA Replication; Ethyl Methanesulfonate; Humans; Hydroxyurea; Lymphocytes; Mitomycin; Mitomycins; Sister Chromatid Exchange | 1986 |
Adult-specific neurons in the nervous system of the moth, Manduca sexta: selective chemical ablation using hydroxyurea.
Topics: Animals; Cell Count; Cell Differentiation; Cell Division; Central Nervous System; Cytarabine; Hydroxyurea; Larva; Lepidoptera; Metamorphosis, Biological; Mitomycin; Mitomycins; Moths; Nerve Degeneration; Neuronal Plasticity; Neurons; Stem Cells | 1986 |
IFN-gamma facilitates NGF-induced neuronal differentiation in PC12 cells.
Topics: Adrenal Gland Neoplasms; Animals; Cell Differentiation; Cell Survival; Colchicine; Cytarabine; Hydroxyurea; Interferon-gamma; Mice; Mitomycin; Mitomycins; Nerve Growth Factors; Neurons; Pheochromocytoma; Rats; Recombinant Proteins; Tumor Cells, Cultured | 1988 |
Characteristics of T cells involved in the expression of delayed hypersensitivity and tumor rejection immunity to 13762A rat mammary adenocarcinoma.
Topics: Adenocarcinoma; Animals; Antigens, Neoplasm; Antigens, Surface; Cyclophosphamide; Female; Hydroxyurea; Hypersensitivity, Delayed; Immunization, Passive; Mammary Neoplasms, Experimental; Mitomycin; Mitomycins; Rats; Rats, Inbred F344; T-Lymphocytes; Vinblastine | 1985 |
DNA synthesis inhibitors block protein synthesis in the human lymphocyte.
Topics: Blood Proteins; Cytarabine; DNA; Humans; Hydroxyurea; In Vitro Techniques; Leucine; Lymphocytes; Lymphokines; Mitogens; Mitomycin; Mitomycins; Phytohemagglutinins; RNA | 1984 |
On the mechanism of 'escape' from desensitization of the cyclic AMP response to TSH in cultured human thyroid cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Cell Division; Cells, Cultured; Cyclic AMP; DNA Replication; Drug Resistance; Humans; Hydroxyurea; Mitomycin; Mitomycins; Thyroid Gland; Thyrotropin; Time Factors | 1984 |
Two-step cell-death kinetics in vitro during cis-platinum, hydroxyurea and mitomycin incubation.
Topics: Antibiotics, Antineoplastic; Cell Line; Cell Survival; Cisplatin; Flow Cytometry; Humans; Hydroxyurea; Kinetics; Leukemia; Mitomycin; Mitomycins | 1984 |
Enhancement of induced sister chromatid exchange and chromosomal aberrations by inhibitors of DNA repair processes.
Topics: Animals; Aphidicolin; Caffeine; Chromosome Aberrations; Cricetinae; Cricetulus; Diterpenes; DNA; DNA Repair; Female; Humans; Hydroxyurea; Mitomycin; Mitomycins; Sister Chromatid Exchange | 1984 |
Potentiation of induced sister chromatid exchanges and chromatid-type aberrations by inhibitors of DNA synthesis and repair in G2.
Topics: Aphidicolin; Caffeine; Cells, Cultured; Chromosome Aberrations; Diterpenes; DNA Repair; DNA Replication; Humans; Hydroxyurea; Interphase; Lymphocytes; Mitomycin; Mitomycins; Sister Chromatid Exchange | 1984 |
Relationship between chromatin structure and replication in mouse L-cells.
Topics: Animals; Chromatin; Cycloheximide; Cytarabine; DNA Replication; Floxuridine; Hydroxyurea; Isoleucine; L Cells; Methotrexate; Mice; Mitomycin; Mitomycins; Protein Biosynthesis; Structure-Activity Relationship | 1980 |
Antagonizing effect of triphenyltin chloride on cytosine-1-beta-D-arabinofuranoside potentiation of chromosome aberrations induced by mitomycin C.
Topics: Animals; Caffeine; CHO Cells; Chromosome Aberrations; Cricetinae; Cytarabine; Drug Antagonism; Drug Synergism; G2 Phase; Hydroxyurea; Mitomycin; Mutagenesis; Organotin Compounds | 1994 |
[The effect of inhibitors on induced mutagenesis].
Topics: Aphidicolin; Caffeine; Cell Line; Cytarabine; DNA Replication; G1 Phase; G2 Phase; Hydroxyurea; Mitomycin; Mutagenesis; Seeds | 1993 |
The effect of a selective 5-lipoxygenase inhibitor, zileuton, on tissue damage in acute colonic inflammation in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Hydroxyurea; Intestinal Mucosa; Leukocyte Count; Leukotriene B4; Lipoxygenase Inhibitors; Male; Mitomycin; Neutrophils; Peroxidase; Rats; Rats, Sprague-Dawley | 1996 |
Effect of hydroxyurea and normal plasma on DNA synthesis in lymphocytes from Fanconi anemia patients.
Topics: Cells, Cultured; Culture Media; Deoxyribonucleotides; DNA; DNA Repair; Enzyme Inhibitors; Fanconi Anemia; Humans; Hydroxyurea; Lymphocytes; Mitomycin; Plasma; Ribonucleotide Reductases | 1996 |
Stimulation of neonatal mouse calvarial bone resorption by the glucocorticoids hydrocortisone and dexamethasone.
Topics: Acetazolamide; Acetylglucosaminidase; Animals; Animals, Newborn; Anti-Inflammatory Agents; Bone Resorption; Calcitonin; Calcium; Dexamethasone; Dinoprostone; Diphosphonates; Dose-Response Relationship, Drug; Enzyme Inhibitors; Granulocyte-Macrophage Colony-Stimulating Factor; Hormone Antagonists; Hydrocortisone; Hydroxyurea; Lysosomes; Mice; Mifepristone; Mitomycin; Parathyroid Hormone; Parietal Bone; Phosphates; Progesterone; Proline | 1996 |
DNA cross-linker-induced G2/M arrest in group C Fanconi anemia lymphoblasts reflects normal checkpoint function.
Topics: Caffeine; Cell Line, Transformed; Cross-Linking Reagents; DNA; DNA Damage; DNA, Complementary; Fanconi Anemia; G2 Phase; Humans; Hydroxyurea; Lymphocytes; Metaphase; Mitomycin; Transfection | 1998 |
Fanconi anemia group A and D cell lines respond normally to inhibitors of cell cycle regulation.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Caffeine; Cell Cycle; Cells, Cultured; Central Nervous System Stimulants; Chromosome Breakage; Cross-Linking Reagents; DNA Adducts; Enzyme Inhibitors; Fanconi Anemia; Humans; Hydrogen Peroxide; Hydroxyurea; Methyl Methanesulfonate; Mitomycin; Oxidants | 1997 |
The effect of hydroxyurea on rabbit subconjunctival fibroblast culture and use of hydroxyurea in rabbits after glaucoma filtration surgery.
Topics: Animals; Cell Adhesion; Cells, Cultured; Conjunctiva; Dose-Response Relationship, Drug; Fibroblasts; Filtering Surgery; Glaucoma; Hydroxyurea; Mitomycin; Nucleic Acid Synthesis Inhibitors; Postoperative Care; Rabbits | 1999 |
Transduction of interphase cells by avian sarcoma virus.
Topics: Active Transport, Cell Nucleus; Animals; Aphidicolin; Avian Sarcoma Viruses; Cell Line; Cell Nucleus; Chick Embryo; DNA, Viral; G2 Phase; Genes, Reporter; Genetic Vectors; Green Fluorescent Proteins; HeLa Cells; Humans; Hydroxyurea; Interphase; Luminescent Proteins; Mice; Mice, Inbred C57BL; Mitomycin; Mitosis; Neurons; Nocodazole; Research Design; Transduction, Genetic | 2002 |
Schizosaccharomyces pombe checkpoint response to DNA interstrand cross-links.
Topics: Camptothecin; Cell Survival; Checkpoint Kinase 2; Cisplatin; Cross-Linking Reagents; DNA; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Enzyme Inhibitors; G2 Phase; Hydroxyurea; Mitomycin; Nucleic Acid Synthesis Inhibitors; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Radiation-Sensitizing Agents; Recombination, Genetic; S Phase; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Temperature; Time Factors | 2003 |
Correlation of sister chromatid exchange formation through homologous recombination with ribonucleotide reductase inhibition.
Topics: Alkylating Agents; Animals; CHO Cells; Cricetinae; Cricetulus; Crossing Over, Genetic; DNA Replication; Enzyme Inhibitors; Hydroxyurea; Mitomycin; Protein Subunits; Resveratrol; Ribonucleotide Reductases; Sister Chromatid Exchange; Stilbenes; Structure-Activity Relationship; Time Factors | 2004 |
Relative cytotoxicity values at the lowest effective concentration for 12 positive chemicals in the in vitro micronucleus test utilizing Chinese hamster ovary cells.
Topics: Animals; Benz(a)Anthracenes; Bleomycin; Cell Count; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Cyclophosphamide; Dactinomycin; Dose-Response Relationship, Drug; Etoposide; Female; Griseofulvin; Hazardous Substances; Hydrogen Peroxide; Hydroxyurea; Methyl Methanesulfonate; Mitomycin; Phenol; Vinblastine | 2004 |
DNA lesion-specific co-localization of the Mre11/Rad50/Nbs1 (MRN) complex and replication protein A (RPA) to repair foci.
Topics: Acid Anhydride Hydrolases; Blotting, Western; Camptothecin; Cations; Cell Cycle Proteins; Cell Nucleus; Comet Assay; DNA; DNA Damage; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; DNA, Single-Stranded; Etoposide; HeLa Cells; Humans; Hydroxyurea; Macromolecular Substances; Microscopy, Fluorescence; Mitomycin; Models, Biological; MRE11 Homologue Protein; Multiprotein Complexes; Nuclear Proteins; Phosphorylation; Protein Binding; Replication Protein A; Time Factors | 2005 |
Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7.
Topics: Actins; Active Transport, Cell Nucleus; Adaptor Proteins, Signal Transducing; Animals; Ataxia Telangiectasia Mutated Proteins; Cell Cycle; Cell Cycle Proteins; Cell Nucleus; Cell Proliferation; Cell Shape; Cytoplasm; Cytoskeletal Proteins; DNA Damage; DNA-Binding Proteins; GTP-Binding Proteins; HeLa Cells; Humans; Hydroxyurea; Mice; Mice, Knockout; Mitomycin; Multiprotein Complexes; Mutagens; Nuclear Proteins; Oncogene Proteins; Phenotype; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Serine-Threonine Kinases; RNA Interference; RNA, Small Interfering; Septins; Signal Transduction; Suppressor of Cytokine Signaling Proteins; Time Factors; Transfection; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Ultraviolet Rays | 2007 |
Differential expression of TP53 associated genes in Fanconi anemia cells after mitomycin C and hydroxyurea treatment.
Topics: Cell Line; Chromosome Aberrations; Cross-Linking Reagents; DNA Damage; Fanconi Anemia; Gene Expression Regulation; Genes, p53; Humans; Hydroxyurea; Mitomycin; Nucleic Acid Synthesis Inhibitors | 2008 |
Differential requirement for H2AX and 53BP1 in organismal development and genome maintenance in the absence of poly(ADP)ribosyl polymerase 1.
Topics: Aging; Animals; B-Lymphocytes; Chromosomal Proteins, Non-Histone; DNA; DNA Breaks, Double-Stranded; DNA Repair; DNA-Activated Protein Kinase; DNA-Binding Proteins; Female; Genome; Genomic Instability; Histones; Humans; Hydroxyurea; In Situ Hybridization, Fluorescence; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Knockout; Mitomycin; Nuclear Proteins; Nucleic Acid Synthesis Inhibitors; Phenotype; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Rad51 Recombinase; Radiation, Ionizing; Sister Chromatid Exchange; Tumor Suppressor p53-Binding Protein 1 | 2010 |
The Arabidopsis SWR1 chromatin-remodeling complex is important for DNA repair, somatic recombination, and meiosis.
Topics: Antineoplastic Agents; Arabidopsis; Arabidopsis Proteins; Chromosomal Proteins, Non-Histone; DNA Damage; DNA Repair; DNA, Bacterial; Fertility; Gametogenesis, Plant; Homologous Recombination; Hydroxyurea; Meiosis; Microfilament Proteins; Mitomycin; Multiprotein Complexes; Mutagenesis, Insertional; Mutation; Protein Subunits; Transcription Factors; Ultraviolet Rays | 2013 |
Differential contribution of the Fanconi anemia-related proteins to repair of several types of DNA damage in cultured silkworm cells.
Topics: Animals; Bombyx; Camptothecin; Cells, Cultured; DNA Damage; DNA Helicases; DNA Repair; Fanconi Anemia Complementation Group D2 Protein; Histones; Homologous Recombination; Humans; Hydroxyurea; Mitomycin; Phosphorylation; Ubiquitination | 2014 |
The leukemia-associated Rho guanine nucleotide exchange factor LARG is required for efficient replication stress signaling.
Topics: Antigens; Ataxia Telangiectasia Mutated Proteins; Cell Survival; Centrosome; Checkpoint Kinase 1; DNA Repair; DNA Replication; HCT116 Cells; HEK293 Cells; HeLa Cells; Humans; Hydroxyurea; Mitomycin; Phosphorylation; Protein Kinases; Rho Guanine Nucleotide Exchange Factors; rhoA GTP-Binding Protein; RNA, Small Interfering; Signal Transduction; Telomere-Binding Proteins | 2014 |
Hydroxyurea induces chromosomal damage in G2 and enhances the clastogenic effect of mitomycin C in Fanconi anemia cells.
Topics: Cell Line; Chromosome Aberrations; Cytogenetic Analysis; Drug Synergism; Fanconi Anemia; G2 Phase; Healthy Volunteers; Humans; Hydroxyurea; Lymphocytes; Mitomycin; Mutagens; Oxidative Stress | 2015 |
Ginsenoside Rg1 impairs homologous recombination repair by targeting CtBP-interacting protein and sensitizes hepatoblastoma cells to DNA damage.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Carrier Proteins; Cell Growth Processes; Cell Line, Tumor; DNA Damage; Drug Synergism; Endodeoxyribonucleases; Ginsenosides; Hep G2 Cells; Hepatoblastoma; Humans; Hydroxyurea; Liver Neoplasms; Male; Mice; Mice, Nude; Mitomycin; Nuclear Proteins; Phthalazines; Piperazines; Random Allocation; Recombinational DNA Repair; Xenograft Model Antitumor Assays | 2018 |
SUMO-1 modification of FEN1 facilitates its interaction with Rad9-Rad1-Hus1 to counteract DNA replication stress.
Topics: Cell Cycle Proteins; DNA Breaks, Double-Stranded; DNA Replication; Exonucleases; Flap Endonucleases; HeLa Cells; Humans; Hydroxyurea; Mitomycin; Mutation; Phosphorylation; SUMO-1 Protein; Sumoylation; Ultraviolet Rays | 2018 |
Succinylation at a key residue of FEN1 is involved in the DNA damage response to maintain genome stability.
Topics: Camptothecin; Cell Cycle Proteins; DNA Damage; DNA Repair; DNA Replication; Exonucleases; Flap Endonucleases; Genome, Human; Genomic Instability; Humans; Hydroxyurea; Mitomycin; Multiprotein Complexes; Proliferating Cell Nuclear Antigen; Protein Processing, Post-Translational; Succinic Acid; SUMO-1 Protein; Sumoylation; Ultraviolet Rays | 2020 |
Fanconi anemia and mTOR pathways functionally interact during stalled replication fork recovery.
Topics: Aphidicolin; Cell Survival; DNA; DNA Repair; DNA Replication; Fanconi Anemia; Fanconi Anemia Complementation Group D2 Protein; Fibroblasts; Genome, Human; Genomic Instability; Humans; Hydroxyurea; Mitomycin; Primary Cell Culture; Protein Binding; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases | 2021 |