hydroxyurea and mitomycin

hydroxyurea has been researched along with mitomycin in 48 studies

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-199017 (35.42)18.7374
1990's10 (20.83)18.2507
2000's9 (18.75)29.6817
2010's10 (20.83)24.3611
2020's2 (4.17)2.80

Authors

AuthorsStudies
Hansch, C; Khwaja, TA; Selassie, CD1
Dias, CB; Hansch, C; Khwaja, TA; Pentecost, S; Selassie, CD1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Rossman, TG; Wolosin, D1
Apostolidis, T; Daniilidis, J; Fountzilas, G; Kalogera-Fountzila, A; Tourkantonis, A; Vritsios, A1
Anastasakis, C; Daniilidis, J; Delis, V; Fountzilas, G; Haritanti, A; Nicolaou, A; Sideras, T; Sridhar, K; Vritsios, A1
Cortés, F; Mateos, S; Ortiz, T; Piñero, J1
Portnoĭ, AS1
Sakaguchi, K; Sono, A1
Oikawa, A; Tohda, H1
Booker, R; Truman, JW1
Calissano, P; Coccia, EM; Di Luzio, A; Improta, T; Romeo, G; Salvatore, AM1
Bartlett, GL; Howell, LE; Kreider, JW1
Albert, DA; Bluestein, HG1
Filetti, S; Rapoport, B; Seto, P1
Böhmer, RM1
De Salvia, R; Degrassi, F; Fiore, M; Palitti, F; Tanzarella, C2
De Vecchis, L; Lagomarsino Caprino, MC; Mazzei, T; Periti, P; Popoli, P1
Dardick, I; Dubsky, M; Kiss, G; Setterfield, G; Sheinin, R1
Kozuka, H; Miyahara, T; Sakaguchi, M; Yamada, H1
Dubinina, LG1
Broutman, L; Callaghan, C; Doria, MI; Eiznhamer, D; Keshavarzian, A; Zarif, A1
Carnevale, A; Frias, S; Gómez, L; Molina, B; Ostrosky-Wegman, P; Rojas, E1
Conaway, HH; Grigorie, D; Lerner, UH1
Bagby, GC; Bakke, AC; Brown, MG; Grompe, M; Heinrich, MC; Hoatlin, ME; Keeble, WW; Magenis, RE; Olson, SB; Reifsteck, CA; Silvey, KV; Zhi, Y; Zigler, AJ1
Johnstone, P; Kohler, S; Moses, RE; Olson, S; Reifsteck, C; Worland, P1
Aksu, G; Bagci, G; Duranoglu, Y; Lüleci, G; Oztürk, A; Yücel, I1
Eifel, PJ1
Boimel, P; Darby, K; Greger, JG; Katz, RA; Rall, GF; Skalka, AM1
Barber, LJ; Carr, AM; Hartley, JA; Lambert, S; Mason, SJ; McHugh, PJ; Pearce, JA1
Fukuhara, K; Jenssen, D; Johansson, F; Lundin, C; Matsuoka, A; Onfelt, A; Sahlin, M; Sjöberg, BM1
Garriott, ML; Hoffman, WP; Lee, C; Murphy, GP; Phelps, JB1
Bissler, JJ; Dixon, K; Lu, L; Robison, JG1
Adang, LA; Kremer, BE; Macara, IG1
Acuña, H; Coleman, MA; Frias, S; Gómez, L; Hinz, JM; Jones, IM; Martinez, A; Molina, B1
Moore, DH1
Escudero, B; Franco, S; Gesheva, S; Huso, DL; Liu, G; Orsburn, B; Prakash, M1
Cigliano, RA; Mittelsten Scheid, O; Rosa, M; Schlögelhofer, P; Von Harder, M1
Kusakabe, T; Lee, JM; Mon, H; Shiotsuki, T; Sugahara, R1
Beveridge, RD; Boulton, SJ; Collis, SJ; Maslen, S; Myers, KN; Patil, AA; Skehel, JM; Staples, CJ1
Altamirano-Lozano, M; Carnevale, A; Frias, S; Gómez, L; Marchetti, F; Molina, B; Ortiz, R; Ramos, S; Torres, L1
Gu, S; Jin, L; Ma, J; Ni, X; Pan, Q; Wang, J; Xu, M; Zhen, N; Zhu, J1
Chen, Y; Guo, Z; Hua, Y; Shen, B; Shi, R; Tian, B; Truong, K; Wang, L; Xu, H; Xu, X; Zhao, Y; Zheng, L; Zhou, M1
Gao, Y; Hua, Y; Mao, S; Shi, R; Song, S; Tian, B; Wang, L; Wang, Y; Xiao, Y; Xu, H; Xu, X; Zhao, Y1
Chaudhury, I; Holz, MK; Knudson, K; Nolan, M1

Reviews

4 review(s) available for hydroxyurea and mitomycin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Chemotherapy of prostatic cancer].
    Voprosy onkologii, 1985, Volume: 31, Issue:9

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Dacarbazine; Diethylstilbestrol; Doxorubicin; Estramustine; Fluorouracil; Humans; Hydroxyurea; Male; Melphalan; Methotrexate; Mitomycin; Mitomycins; Prednisolone; Procarbazine; Prostatic Neoplasms; Streptozocin; Vincristine

1985
Chemoradiation for carcinoma of the cervix: advances and opportunities.
    Radiation research, 2000, Volume: 154, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Hysterectomy; Lung Neoplasms; Mitomycin; Prospective Studies; Radiation Tolerance; Radiation-Sensitizing Agents; Randomized Controlled Trials as Topic; Survival Rate; Treatment Outcome; Uterine Cervical Neoplasms; Vincristine

2000
Combined chemotherapy and radiation therapy for cervical cancer.
    Journal of the National Comprehensive Cancer Network : JNCCN, 2004, Volume: 2, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials, Phase III as Topic; Combined Modality Therapy; Female; Fluorouracil; Humans; Hydroxyurea; Mitomycin; Nitroimidazoles; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms

2004

Trials

2 trial(s) available for hydroxyurea and mitomycin

ArticleYear
Induction chemotherapy with cisplatinum, 5-fluorouracil, bleomycin, mitomycin C and hydroxyurea for previously untreated locally advanced squamous cell carcinomas of the head and neck.
    Archives of oto-rhino-laryngology, 1989, Volume: 246, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Mitomycin; Mitomycins; Neck Dissection; Neoplasm Staging

1989
Preliminary research on the evaluation of some prognostic factors in a randomized study of adjuvant immunochemotherapy in colorectal adenocarcinoma.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1984, Volume: 3, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Colonic Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Humans; Hydroxyurea; Male; Middle Aged; Mitomycin; Mitomycins; Prognosis; Rectal Neoplasms; Semustine

1984

Other Studies

42 other study(ies) available for hydroxyurea and mitomycin

ArticleYear
Structure-activity relationships of antineoplastic agents in multidrug resistance.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:7

    Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured

1990
Comparative structure-activity relationships of antifolate triazines inhibiting murine tumor cells sensitive and resistant to methotrexate.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:3

    Topics: Animals; Chemical Phenomena; Chemistry, Physical; Chickens; Drug Resistance; Folic Acid Antagonists; Humans; Leukemia L5178; Leukemia, Experimental; Mathematics; Methotrexate; Mice; Structure-Activity Relationship; Triazines

1984
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Differential susceptibility to carcinogen-induced amplification of SV40 and dhfr sequences in SV40-transformed human keratinocytes.
    Molecular carcinogenesis, 1992, Volume: 6, Issue:3

    Topics: Aphidicolin; Carcinogens; Cell Line, Transformed; Cell Transformation, Viral; Cycloheximide; Drug Resistance; Gene Amplification; Genes, Viral; Humans; Hydroxyurea; Keratinocytes; Methotrexate; Mitomycin; Proto-Oncogene Mas; Simian virus 40; Tetrahydrofolate Dehydrogenase; Time Factors; Ultraviolet Rays; X-Rays

1992
[Combined therapy of locally advanced squamous epithelial cancers in the area of the head and neck].
    Laryngologie, Rhinologie, Otologie, 1988, Volume: 67, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Middle Aged; Mitomycin; Mitomycins

1988
G2 effects of DNA-repair inhibitors on chromatid-type aberrations in root-tip cells treated with maleic hydrazide and mitomycin C.
    Mutation research, 1989, Volume: 226, Issue:2

    Topics: Caffeine; Cell Cycle; Chromosome Aberrations; Chromosomes; Cytarabine; DNA Damage; DNA Repair; Floxuridine; Hydroxyurea; In Vitro Techniques; Interphase; Maleic Hydrazide; Mitomycin; Mitomycins; Plants; Pyridazines; Thymidine

1989
The influence of a protein synthesis inhibitor on sister-chromatid exchange in the plant Vicia faba.
    Mutation research, 1986, Volume: 173, Issue:4

    Topics: Chromosome Aberrations; Cycloheximide; DNA Replication; Fabaceae; Hydroxyurea; Mitomycin; Mitomycins; Plant Proteins; Plants, Medicinal; Sister Chromatid Exchange

1986
Proliferation-dependent reduction of sister-chromatid exchange frequency induced by mitomycin C in human lymphoblastoid cells and its suppression by inhibitors of DNA replication.
    Mutation research, 1986, Volume: 163, Issue:2

    Topics: 4-Nitroquinoline-1-oxide; Cell Division; Cycloheximide; Cytarabine; Depression, Chemical; DNA Repair; DNA Replication; Ethyl Methanesulfonate; Humans; Hydroxyurea; Lymphocytes; Mitomycin; Mitomycins; Sister Chromatid Exchange

1986
Adult-specific neurons in the nervous system of the moth, Manduca sexta: selective chemical ablation using hydroxyurea.
    Journal of neurobiology, 1986, Volume: 17, Issue:6

    Topics: Animals; Cell Count; Cell Differentiation; Cell Division; Central Nervous System; Cytarabine; Hydroxyurea; Larva; Lepidoptera; Metamorphosis, Biological; Mitomycin; Mitomycins; Moths; Nerve Degeneration; Neuronal Plasticity; Neurons; Stem Cells

1986
IFN-gamma facilitates NGF-induced neuronal differentiation in PC12 cells.
    Experimental cell research, 1988, Volume: 179, Issue:1

    Topics: Adrenal Gland Neoplasms; Animals; Cell Differentiation; Cell Survival; Colchicine; Cytarabine; Hydroxyurea; Interferon-gamma; Mice; Mitomycin; Mitomycins; Nerve Growth Factors; Neurons; Pheochromocytoma; Rats; Recombinant Proteins; Tumor Cells, Cultured

1988
Characteristics of T cells involved in the expression of delayed hypersensitivity and tumor rejection immunity to 13762A rat mammary adenocarcinoma.
    Cellular immunology, 1985, Volume: 93, Issue:1

    Topics: Adenocarcinoma; Animals; Antigens, Neoplasm; Antigens, Surface; Cyclophosphamide; Female; Hydroxyurea; Hypersensitivity, Delayed; Immunization, Passive; Mammary Neoplasms, Experimental; Mitomycin; Mitomycins; Rats; Rats, Inbred F344; T-Lymphocytes; Vinblastine

1985
DNA synthesis inhibitors block protein synthesis in the human lymphocyte.
    International journal of immunopharmacology, 1984, Volume: 6, Issue:2

    Topics: Blood Proteins; Cytarabine; DNA; Humans; Hydroxyurea; In Vitro Techniques; Leucine; Lymphocytes; Lymphokines; Mitogens; Mitomycin; Mitomycins; Phytohemagglutinins; RNA

1984
On the mechanism of 'escape' from desensitization of the cyclic AMP response to TSH in cultured human thyroid cells.
    Molecular and cellular endocrinology, 1984, Volume: 36, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Cell Division; Cells, Cultured; Cyclic AMP; DNA Replication; Drug Resistance; Humans; Hydroxyurea; Mitomycin; Mitomycins; Thyroid Gland; Thyrotropin; Time Factors

1984
Two-step cell-death kinetics in vitro during cis-platinum, hydroxyurea and mitomycin incubation.
    Cell and tissue kinetics, 1984, Volume: 17, Issue:6

    Topics: Antibiotics, Antineoplastic; Cell Line; Cell Survival; Cisplatin; Flow Cytometry; Humans; Hydroxyurea; Kinetics; Leukemia; Mitomycin; Mitomycins

1984
Enhancement of induced sister chromatid exchange and chromosomal aberrations by inhibitors of DNA repair processes.
    Toxicologic pathology, 1984, Volume: 12, Issue:3

    Topics: Animals; Aphidicolin; Caffeine; Chromosome Aberrations; Cricetinae; Cricetulus; Diterpenes; DNA; DNA Repair; Female; Humans; Hydroxyurea; Mitomycin; Mitomycins; Sister Chromatid Exchange

1984
Potentiation of induced sister chromatid exchanges and chromatid-type aberrations by inhibitors of DNA synthesis and repair in G2.
    Basic life sciences, 1984, Volume: 29 Pt A

    Topics: Aphidicolin; Caffeine; Cells, Cultured; Chromosome Aberrations; Diterpenes; DNA Repair; DNA Replication; Humans; Hydroxyurea; Interphase; Lymphocytes; Mitomycin; Mitomycins; Sister Chromatid Exchange

1984
Relationship between chromatin structure and replication in mouse L-cells.
    Canadian journal of biochemistry, 1980, Volume: 58, Issue:12

    Topics: Animals; Chromatin; Cycloheximide; Cytarabine; DNA Replication; Floxuridine; Hydroxyurea; Isoleucine; L Cells; Methotrexate; Mice; Mitomycin; Mitomycins; Protein Biosynthesis; Structure-Activity Relationship

1980
Antagonizing effect of triphenyltin chloride on cytosine-1-beta-D-arabinofuranoside potentiation of chromosome aberrations induced by mitomycin C.
    Mutation research, 1994, Volume: 323, Issue:3

    Topics: Animals; Caffeine; CHO Cells; Chromosome Aberrations; Cricetinae; Cytarabine; Drug Antagonism; Drug Synergism; G2 Phase; Hydroxyurea; Mitomycin; Mutagenesis; Organotin Compounds

1994
[The effect of inhibitors on induced mutagenesis].
    Genetika, 1993, Volume: 29, Issue:8

    Topics: Aphidicolin; Caffeine; Cell Line; Cytarabine; DNA Replication; G1 Phase; G2 Phase; Hydroxyurea; Mitomycin; Mutagenesis; Seeds

1993
The effect of a selective 5-lipoxygenase inhibitor, zileuton, on tissue damage in acute colonic inflammation in rats.
    Inflammation, 1996, Volume: 20, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Hydroxyurea; Intestinal Mucosa; Leukocyte Count; Leukotriene B4; Lipoxygenase Inhibitors; Male; Mitomycin; Neutrophils; Peroxidase; Rats; Rats, Sprague-Dawley

1996
Effect of hydroxyurea and normal plasma on DNA synthesis in lymphocytes from Fanconi anemia patients.
    Mutation research, 1996, Oct-25, Volume: 357, Issue:1-2

    Topics: Cells, Cultured; Culture Media; Deoxyribonucleotides; DNA; DNA Repair; Enzyme Inhibitors; Fanconi Anemia; Humans; Hydroxyurea; Lymphocytes; Mitomycin; Plasma; Ribonucleotide Reductases

1996
Stimulation of neonatal mouse calvarial bone resorption by the glucocorticoids hydrocortisone and dexamethasone.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1996, Volume: 11, Issue:10

    Topics: Acetazolamide; Acetylglucosaminidase; Animals; Animals, Newborn; Anti-Inflammatory Agents; Bone Resorption; Calcitonin; Calcium; Dexamethasone; Dinoprostone; Diphosphonates; Dose-Response Relationship, Drug; Enzyme Inhibitors; Granulocyte-Macrophage Colony-Stimulating Factor; Hormone Antagonists; Hydrocortisone; Hydroxyurea; Lysosomes; Mice; Mifepristone; Mitomycin; Parathyroid Hormone; Parietal Bone; Phosphates; Progesterone; Proline

1996
DNA cross-linker-induced G2/M arrest in group C Fanconi anemia lymphoblasts reflects normal checkpoint function.
    Blood, 1998, Jan-01, Volume: 91, Issue:1

    Topics: Caffeine; Cell Line, Transformed; Cross-Linking Reagents; DNA; DNA Damage; DNA, Complementary; Fanconi Anemia; G2 Phase; Humans; Hydroxyurea; Lymphocytes; Metaphase; Mitomycin; Transfection

1998
Fanconi anemia group A and D cell lines respond normally to inhibitors of cell cycle regulation.
    Somatic cell and molecular genetics, 1997, Volume: 23, Issue:6

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Caffeine; Cell Cycle; Cells, Cultured; Central Nervous System Stimulants; Chromosome Breakage; Cross-Linking Reagents; DNA Adducts; Enzyme Inhibitors; Fanconi Anemia; Humans; Hydrogen Peroxide; Hydroxyurea; Methyl Methanesulfonate; Mitomycin; Oxidants

1997
The effect of hydroxyurea on rabbit subconjunctival fibroblast culture and use of hydroxyurea in rabbits after glaucoma filtration surgery.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1999, Volume: 213, Issue:5

    Topics: Animals; Cell Adhesion; Cells, Cultured; Conjunctiva; Dose-Response Relationship, Drug; Fibroblasts; Filtering Surgery; Glaucoma; Hydroxyurea; Mitomycin; Nucleic Acid Synthesis Inhibitors; Postoperative Care; Rabbits

1999
Transduction of interphase cells by avian sarcoma virus.
    Journal of virology, 2002, Volume: 76, Issue:11

    Topics: Active Transport, Cell Nucleus; Animals; Aphidicolin; Avian Sarcoma Viruses; Cell Line; Cell Nucleus; Chick Embryo; DNA, Viral; G2 Phase; Genes, Reporter; Genetic Vectors; Green Fluorescent Proteins; HeLa Cells; Humans; Hydroxyurea; Interphase; Luminescent Proteins; Mice; Mice, Inbred C57BL; Mitomycin; Mitosis; Neurons; Nocodazole; Research Design; Transduction, Genetic

2002
Schizosaccharomyces pombe checkpoint response to DNA interstrand cross-links.
    Molecular and cellular biology, 2003, Volume: 23, Issue:13

    Topics: Camptothecin; Cell Survival; Checkpoint Kinase 2; Cisplatin; Cross-Linking Reagents; DNA; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Enzyme Inhibitors; G2 Phase; Hydroxyurea; Mitomycin; Nucleic Acid Synthesis Inhibitors; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Radiation-Sensitizing Agents; Recombination, Genetic; S Phase; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Temperature; Time Factors

2003
Correlation of sister chromatid exchange formation through homologous recombination with ribonucleotide reductase inhibition.
    Mutation research, 2004, Mar-22, Volume: 547, Issue:1-2

    Topics: Alkylating Agents; Animals; CHO Cells; Cricetinae; Cricetulus; Crossing Over, Genetic; DNA Replication; Enzyme Inhibitors; Hydroxyurea; Mitomycin; Protein Subunits; Resveratrol; Ribonucleotide Reductases; Sister Chromatid Exchange; Stilbenes; Structure-Activity Relationship; Time Factors

2004
Relative cytotoxicity values at the lowest effective concentration for 12 positive chemicals in the in vitro micronucleus test utilizing Chinese hamster ovary cells.
    Mutation research, 2004, Jul-11, Volume: 561, Issue:1-2

    Topics: Animals; Benz(a)Anthracenes; Bleomycin; Cell Count; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Cyclophosphamide; Dactinomycin; Dose-Response Relationship, Drug; Etoposide; Female; Griseofulvin; Hazardous Substances; Hydrogen Peroxide; Hydroxyurea; Methyl Methanesulfonate; Mitomycin; Phenol; Vinblastine

2004
DNA lesion-specific co-localization of the Mre11/Rad50/Nbs1 (MRN) complex and replication protein A (RPA) to repair foci.
    The Journal of biological chemistry, 2005, Apr-01, Volume: 280, Issue:13

    Topics: Acid Anhydride Hydrolases; Blotting, Western; Camptothecin; Cations; Cell Cycle Proteins; Cell Nucleus; Comet Assay; DNA; DNA Damage; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; DNA, Single-Stranded; Etoposide; HeLa Cells; Humans; Hydroxyurea; Macromolecular Substances; Microscopy, Fluorescence; Mitomycin; Models, Biological; MRE11 Homologue Protein; Multiprotein Complexes; Nuclear Proteins; Phosphorylation; Protein Binding; Replication Protein A; Time Factors

2005
Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7.
    Cell, 2007, Sep-07, Volume: 130, Issue:5

    Topics: Actins; Active Transport, Cell Nucleus; Adaptor Proteins, Signal Transducing; Animals; Ataxia Telangiectasia Mutated Proteins; Cell Cycle; Cell Cycle Proteins; Cell Nucleus; Cell Proliferation; Cell Shape; Cytoplasm; Cytoskeletal Proteins; DNA Damage; DNA-Binding Proteins; GTP-Binding Proteins; HeLa Cells; Humans; Hydroxyurea; Mice; Mice, Knockout; Mitomycin; Multiprotein Complexes; Mutagens; Nuclear Proteins; Oncogene Proteins; Phenotype; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Serine-Threonine Kinases; RNA Interference; RNA, Small Interfering; Septins; Signal Transduction; Suppressor of Cytokine Signaling Proteins; Time Factors; Transfection; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Ultraviolet Rays

2007
Differential expression of TP53 associated genes in Fanconi anemia cells after mitomycin C and hydroxyurea treatment.
    Mutation research, 2008, Oct-30, Volume: 656, Issue:1-2

    Topics: Cell Line; Chromosome Aberrations; Cross-Linking Reagents; DNA Damage; Fanconi Anemia; Gene Expression Regulation; Genes, p53; Humans; Hydroxyurea; Mitomycin; Nucleic Acid Synthesis Inhibitors

2008
Differential requirement for H2AX and 53BP1 in organismal development and genome maintenance in the absence of poly(ADP)ribosyl polymerase 1.
    Molecular and cellular biology, 2010, Volume: 30, Issue:10

    Topics: Aging; Animals; B-Lymphocytes; Chromosomal Proteins, Non-Histone; DNA; DNA Breaks, Double-Stranded; DNA Repair; DNA-Activated Protein Kinase; DNA-Binding Proteins; Female; Genome; Genomic Instability; Histones; Humans; Hydroxyurea; In Situ Hybridization, Fluorescence; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Knockout; Mitomycin; Nuclear Proteins; Nucleic Acid Synthesis Inhibitors; Phenotype; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Rad51 Recombinase; Radiation, Ionizing; Sister Chromatid Exchange; Tumor Suppressor p53-Binding Protein 1

2010
The Arabidopsis SWR1 chromatin-remodeling complex is important for DNA repair, somatic recombination, and meiosis.
    The Plant cell, 2013, Volume: 25, Issue:6

    Topics: Antineoplastic Agents; Arabidopsis; Arabidopsis Proteins; Chromosomal Proteins, Non-Histone; DNA Damage; DNA Repair; DNA, Bacterial; Fertility; Gametogenesis, Plant; Homologous Recombination; Hydroxyurea; Meiosis; Microfilament Proteins; Mitomycin; Multiprotein Complexes; Mutagenesis, Insertional; Mutation; Protein Subunits; Transcription Factors; Ultraviolet Rays

2013
Differential contribution of the Fanconi anemia-related proteins to repair of several types of DNA damage in cultured silkworm cells.
    FEBS letters, 2014, Nov-03, Volume: 588, Issue:21

    Topics: Animals; Bombyx; Camptothecin; Cells, Cultured; DNA Damage; DNA Helicases; DNA Repair; Fanconi Anemia Complementation Group D2 Protein; Histones; Homologous Recombination; Humans; Hydroxyurea; Mitomycin; Phosphorylation; Ubiquitination

2014
The leukemia-associated Rho guanine nucleotide exchange factor LARG is required for efficient replication stress signaling.
    Cell cycle (Georgetown, Tex.), 2014, Volume: 13, Issue:21

    Topics: Antigens; Ataxia Telangiectasia Mutated Proteins; Cell Survival; Centrosome; Checkpoint Kinase 1; DNA Repair; DNA Replication; HCT116 Cells; HEK293 Cells; HeLa Cells; Humans; Hydroxyurea; Mitomycin; Phosphorylation; Protein Kinases; Rho Guanine Nucleotide Exchange Factors; rhoA GTP-Binding Protein; RNA, Small Interfering; Signal Transduction; Telomere-Binding Proteins

2014
Hydroxyurea induces chromosomal damage in G2 and enhances the clastogenic effect of mitomycin C in Fanconi anemia cells.
    Environmental and molecular mutagenesis, 2015, Volume: 56, Issue:5

    Topics: Cell Line; Chromosome Aberrations; Cytogenetic Analysis; Drug Synergism; Fanconi Anemia; G2 Phase; Healthy Volunteers; Humans; Hydroxyurea; Lymphocytes; Mitomycin; Mutagens; Oxidative Stress

2015
Ginsenoside Rg1 impairs homologous recombination repair by targeting CtBP-interacting protein and sensitizes hepatoblastoma cells to DNA damage.
    Anti-cancer drugs, 2018, Volume: 29, Issue:8

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Carrier Proteins; Cell Growth Processes; Cell Line, Tumor; DNA Damage; Drug Synergism; Endodeoxyribonucleases; Ginsenosides; Hep G2 Cells; Hepatoblastoma; Humans; Hydroxyurea; Liver Neoplasms; Male; Mice; Mice, Nude; Mitomycin; Nuclear Proteins; Phthalazines; Piperazines; Random Allocation; Recombinational DNA Repair; Xenograft Model Antitumor Assays

2018
SUMO-1 modification of FEN1 facilitates its interaction with Rad9-Rad1-Hus1 to counteract DNA replication stress.
    Journal of molecular cell biology, 2018, 10-01, Volume: 10, Issue:5

    Topics: Cell Cycle Proteins; DNA Breaks, Double-Stranded; DNA Replication; Exonucleases; Flap Endonucleases; HeLa Cells; Humans; Hydroxyurea; Mitomycin; Mutation; Phosphorylation; SUMO-1 Protein; Sumoylation; Ultraviolet Rays

2018
Succinylation at a key residue of FEN1 is involved in the DNA damage response to maintain genome stability.
    American journal of physiology. Cell physiology, 2020, 10-01, Volume: 319, Issue:4

    Topics: Camptothecin; Cell Cycle Proteins; DNA Damage; DNA Repair; DNA Replication; Exonucleases; Flap Endonucleases; Genome, Human; Genomic Instability; Humans; Hydroxyurea; Mitomycin; Multiprotein Complexes; Proliferating Cell Nuclear Antigen; Protein Processing, Post-Translational; Succinic Acid; SUMO-1 Protein; Sumoylation; Ultraviolet Rays

2020
Fanconi anemia and mTOR pathways functionally interact during stalled replication fork recovery.
    FEBS letters, 2021, Volume: 595, Issue:5

    Topics: Aphidicolin; Cell Survival; DNA; DNA Repair; DNA Replication; Fanconi Anemia; Fanconi Anemia Complementation Group D2 Protein; Fibroblasts; Genome, Human; Genomic Instability; Humans; Hydroxyurea; Mitomycin; Primary Cell Culture; Protein Binding; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases

2021