hydroxyurea has been researched along with methotrexate in 300 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 217 (72.33) | 18.7374 |
| 1990's | 35 (11.67) | 18.2507 |
| 2000's | 28 (9.33) | 29.6817 |
| 2010's | 16 (5.33) | 24.3611 |
| 2020's | 4 (1.33) | 2.80 |
| Authors | Studies |
|---|---|
| Hansch, C; Khwaja, TA; Selassie, CD | 1 |
| Dias, CB; Hansch, C; Khwaja, TA; Pentecost, S; Selassie, CD | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Calvert, AH; Hill, BT; Hughes, KB; Price, LA; Shaw, HJ | 1 |
| DeWys, WD | 1 |
| Borsos, T; Ohanian, SH; Segerling, M | 1 |
| Carter, SK; Goldsmith, MA | 1 |
| Groth, O; Lindgren, S | 1 |
| Barranco, S; Costanzi, JJ; Gagliano, RG; Griffiths, C; Loukas, D | 1 |
| Kaidbey, KH | 1 |
| McMeekin, TO; Moschella, SL | 1 |
| Perlin, E | 1 |
| Busch, S; Endres, P; Rubin, R; Schönen, M; Schulz, V | 1 |
| Bar-Eli, M; Callily, R; Cohen, H; Wahba, A | 1 |
| Zackheim, HS | 1 |
| Carter, SK; Wasserman, TH | 1 |
| Forsdyke, DR; Scott, FW | 1 |
| Brunk, CF; Yaffe, D | 1 |
| Schempp, W; Sigwarth, I; Vogel, W | 1 |
| Azizkhan, JC; Goode, D; Speeg, KV; Stromberg, K | 1 |
| Enomoto, T; Tanuma, S; Yamada, M | 1 |
| Carr, DT; Hansen, HH; Sealy, R; Selawry, OS; Simon, R; Tucker, RD; van Wyk, CE | 1 |
| Hammond, CB; Schmidt, HJ; Suciu, TN; Surwit, EA | 1 |
| Löffler, H; Pralle, H | 1 |
| Fleischer, J | 1 |
| Henderson, JF; Lowe, JK | 1 |
| Brattain, MG; Coleman, MS; Crist, WM; Sarrif, A; Vinson, PC; Vogler, LB | 1 |
| Comaish, JS; Hodge, L | 1 |
| Häyry, P; Soots, A | 1 |
| Buckner, CD; Sanders, JE; Stewart, P; Thomas, ED | 1 |
| Berkman, EM; Caplan, SN | 1 |
| Tam, DW; Urbach, F; Van Scott, EJ | 1 |
| Harmon, JD; Johnson, CM | 1 |
| Necas, E; Neuwirt, J; Ponka, P | 1 |
| Watson, W | 1 |
| Hoffbrand, AV; Wickremasinghe, RG | 2 |
| McDonald, CJ | 4 |
| Groth, O | 1 |
| Broggini, M; Colombo, T; Donelli, MG; Garattini, S | 1 |
| Klem, EB | 1 |
| Kleckow, M; Mattern, J; Vogt-Moykopf, I; Volm, M; Wayss, K | 1 |
| Wohlrab, W; Zaumseil, RP | 1 |
| Block, NL; Camuzzi, F; Claflin, A; Politano, VA; Stover, B; Troner, M | 1 |
| Marsh, JC | 1 |
| Siminovitch, L | 1 |
| Canellos, GP | 1 |
| Abel, EA; Farber, EM; Pearlman, D | 1 |
| Rees, RB | 1 |
| Freeman-Narrod, M | 1 |
| DeSesso, JM; Jordan, RL | 1 |
| Loeffel, ED | 1 |
| Hoffbrand, AV; Hooton, JW | 1 |
| el Ashkar, A; Pazdernik, TL; Uyeki, EM | 1 |
| Moschella, SL | 1 |
| Bergstresser, PR; Schreiber, SH; Weinstein, GD | 1 |
| Neĉas, E; Neuwirt, J | 1 |
| Ruszczak, Z | 2 |
| Rollier, R | 1 |
| Brincker, H | 1 |
| Burchenal, JH; Clarkson, BD; Cunningham, IB; Dowling, MD; Gee, TS | 1 |
| Burchenal, J; D'angio, G; Exelby, P; Fang, S; Lieberman, P; Murphy, ML; Wollner, N | 1 |
| Anderson, PC; Woofter, JC | 1 |
| Haghbin, M | 1 |
| Baker, H | 1 |
| Kaufmann, M; Mattern, J; Volm, M; Wayss, K | 1 |
| Chusid, MJ; Dale, DC | 1 |
| Phillips, FS; Sternberg, SS | 1 |
| Burchenal, JH; D'Angio, GJ; Exelby, PR; Lieberman, PH; Murphy, ML; Wollner, N | 1 |
| Burchenal, JH; D'Angio, G; Exelby, P; Lieberman, PH; Murphy, ML; Wollner, N | 1 |
| Averette, HE; Ford, JH; Girtanner, RE; Hoskins, WJ; Ramos, R; Weinstein, GD | 1 |
| DeLapp, NW; Karasek, MA | 1 |
| Rossman, TG; Wolosin, D | 1 |
| Haraf, DJ; McEvilly, JM; Mick, R; Panje, WR; Vokes, EE; Weichselbaum, RR | 1 |
| Buffoli, A; Frata, P; La Face, B; Morrica, B | 1 |
| Chan, TK; Chiu, E; Liang, R; Todd, D | 1 |
| Davidson, K; Forseth, B; Scott, J; Von Hoff, DD; Waddelow, T; Wahl, G | 1 |
| Golos, B; Malec, J | 1 |
| Asano, S; Inoue, T; Ogura, H; Ozawa, K; Tani, K; Tojo, A | 1 |
| Azizkhan, JC; Eastman, HB; Schmitt, MC; Swick, AG | 1 |
| Arbiser, JL; Arbiser, ZK; Majzoub, JA | 1 |
| Antoniw, P; Bagshawe, KD; Boden, JA; Boxer, GM; Patridge, TA; Pedley, RB; Sharma, K; Southall, PJ | 1 |
| Wolverton, SE | 1 |
| Greene, JA; Kavlock, RJ; Kimmel, GL; Morrissey, RE; Owens, E; Rogers, JM; Sadler, TW; Stack, HF; Waters, MD; Welsch, F | 1 |
| Snapka, RM; Wani, MA | 1 |
| Hancock, MC; Hudson, DL; Smith, HS; Stark, GR; Watt, FM; Wright, JA | 1 |
| Ardiet, JM; Clavel, M; Gignoux, B | 1 |
| Abele, R; Cavalli, F; Grossenbacher, R; Honegger, HP; Mermillod, B; Wolfensberger, M | 1 |
| Abele, R; Cavalli, F; Gervasi, A; Grossenbacher, R; Honegger, HP; Kaplan, E; Lehmann, W; Mermillod, B; Wolfensberger, M | 1 |
| Cox, GS; Park, KH | 1 |
| Gutkowska, J; Konopka, L; Pakulska, J; Pawelski, S | 1 |
| Barnhill, RL; Wiles, JC | 1 |
| Blessing, JA; Curry, SL; DiSaia, PJ; Soper, JT; Twiggs, LB | 1 |
| Clifford, P; Grant, HR | 1 |
| Akiyama, Y; Kiriyama, Y; Kitoh, T; Kubota, M; Mikawa, H; Takimoto, T; Tanizawa, A | 1 |
| Brouns, MC; Fitchen, JH; Riscoe, MK | 1 |
| Malec, J; Przybyszewski, WM | 1 |
| Bolis, G; Bonazzi, C; Landoni, F; Mangili, G; Mangioni, C; Vergadoro, F; Zanaboni, F | 1 |
| Portnoĭ, AS | 1 |
| FitzGerald, GB; Wick, MM | 1 |
| FitzGerald, GB; Ratliff, J; Wick, MM | 1 |
| Wawra, E | 1 |
| Levin, VA | 1 |
| Choo, YC; Ma, HK; Wong, LC | 1 |
| Burhans, WC; Heintz, NH; Selegue, JE | 1 |
| Hahn, P; Kapp, LN; Painter, RB | 1 |
| Shapiro, JR; Shapiro, WR | 1 |
| Champion, RH | 2 |
| Feder, J; Hill, AB; Johnston, RN; Schimke, RT; Sherwood, SW | 1 |
| Bedford, JS; Fox, MH; Read, RA | 1 |
| Hoy, CA; Kovacs, M; Rice, GC; Schimke, RT | 1 |
| Al-Ansari, HM; Farkas, WR; Walden, TL | 1 |
| Schimke, RT; Schumacher, RI; Sherwood, SW | 1 |
| Hayashi, M; Honma, Y; Hozumi, M; Okabe-Kado, J | 1 |
| Bezwoda, WR; Derman, DP; Nissenbaum, M | 1 |
| Bagshawe, KD; Boden, J; Boxer, GM; Britton, DW; Green, A; Partridge, T; Pedley, B; Sharma, S; Southall, P | 1 |
| Boerrigter, GH; Braakhuis, BJ; Heinerman, EC; Snow, GB | 1 |
| Hahn, P; Kapp, LN; Morgan, WF; Painter, RB | 1 |
| Maynard, K; Parsons, PG | 1 |
| Birgens, HS; Geisler, C; Hansen, NE; Hasselbalch, H | 1 |
| Nicander, B; Reichard, P | 1 |
| Bodycote, J; Fero, ML; Hahn, PJ; Kapp, LN; Morgan, WF; Painter, RB; Pantelias, GE | 1 |
| Hill, A; Johnston, RN; Schimke, RT | 1 |
| Moore, JV | 1 |
| Hill, AB; Schimke, RT | 1 |
| Buchanan, GR; Carpentieri, U; Schad, GA; Walterspiel, JN | 1 |
| Sullivan, RD | 1 |
| Pavone-Macaluso, M | 1 |
| Oberfield, RA | 1 |
| Broder, LE; Rall, DP | 1 |
| Bertino, JR; DeConti, RC; Mosher, MB | 1 |
| Devik, F; Hagen, S | 1 |
| Frisby, SA; Oliverio, VT; Zager, RF | 1 |
| Bajetta, E; Bonadonna, G; Tancini, G | 1 |
| Simmonds, WP | 1 |
| Almeyda, J; Levantine, A | 1 |
| Fekete, B; Gergely, P; Petrányi, G; Szabó, G; Szegedi, G | 2 |
| Israel, L | 1 |
| Dantzig, PI | 1 |
| Stephens, FO | 1 |
| Sugiura, K | 1 |
| Watne, AL | 1 |
| Falkson, G; Geddes, EW | 1 |
| Yu, KY | 1 |
| Andreassi, L; Ottolenghi, F | 2 |
| Fox, M; Nias, AH | 1 |
| Smithers, DW | 1 |
| Adamson, DJ; Bowdon, BJ; Vail, MH; Wheeler, GP | 1 |
| Hunter, GA; Simmons, IJ; Thomas, BM | 1 |
| Selawry, OS | 1 |
| Braverman, IM; Cohen, I; O'Keefe, E | 1 |
| Hansen, HH; Krezoski, SK; Muggia, FM | 1 |
| Gelfant, S; Smith, C | 1 |
| Hellmann, K; Murkin, GE | 1 |
| Bailey, I; Kiryabwire, Y; Magrath, IT; Mugerwa, J; Olweny, C | 1 |
| Gallo, RC; Levine, P; Smith, RG; Ting, RC; Whang-Peng, J | 1 |
| Jungi, WF | 1 |
| Burchenal, JH; Clarkson, BD; Haghbin, M; Miké, V; Murphy, ML; Tan, CC | 1 |
| Burchenal, JH; Clarkson, BD; Cunningham, B; Dowling, MD; Gee, TS; Haghbin, M; Tan, CT | 1 |
| Conroy, JF | 1 |
| Newbold, PC | 1 |
| Carter, SK | 1 |
| Baden, HP; Pugliese, MM | 1 |
| Herzberg, JJ | 1 |
| Adamson, RH; Hahn, MA | 1 |
| Comaish, JS; Dahl, MG | 1 |
| Sauer, GC | 1 |
| Comings, DE; Okada, TA | 1 |
| Balconi, G; Bossi, A; Donelli, MG; Filippeschi, S; Franchi, G; Garattini, S; Morasca, L | 1 |
| Cooper, EH | 1 |
| Blackett, NM; Constable, TB; Millar, JL | 1 |
| Benckhuijsen, C | 1 |
| Dano, K; Nissen, NI | 1 |
| Leavell, UW; Yarbro, JW | 1 |
| Byfield, P; Sercarz, EE | 1 |
| Caccialanza, P; Finzi, AF | 1 |
| Stutzman, L | 1 |
| Burns, BC; Rutledge, F; Smith, JP; Soffar, S | 1 |
| Bonder, RH; Van Scott, EJ | 2 |
| Groth, DP; Horwitz, S; Vogler, WR | 1 |
| Byfield, P; Sercarz, E | 1 |
| Brockman, RW; Lloyd, HH; Mellett, LB; Montgomery, JA; Schabel, FM; Skipper, HE; Wilkoff, LJ | 1 |
| Eker, P | 1 |
| Kaung, DT; Swartzendruber, AA | 1 |
| Hills, WJ; Rufino, C; Stehlin, JS | 1 |
| Asselin, B; Bataini, JP; Brugère, J; Garcia-Giralt, E; Jaulerry, M; Jouve, M; Palangie, T; Pouillart, P | 1 |
| Glick, JH; Taylor, SG; Zehngebot, LM | 1 |
| Barzan, L; Comoretto, R; Galligioni, E; Grigoletto, E; Magri, MD; Tirelli, U; Trovò, MG; Tumolo, S; Veronesi, A | 1 |
| Alberto, P; Lehmann, W; Medenica, R | 1 |
| Barnard, DE; Clayton, LA; Currie, JL; Hammond, CB; Weed, JC | 1 |
| Jacobs, C; Mead, GM | 1 |
| Camacho, F; Cinberg, J; Kaplan, BH; Lerner, H; Vogl, SE | 1 |
| Comerford, M; Halprin, KM; Taylor, JR | 1 |
| Spiers, AS | 1 |
| Gonzalez, MF; Sartiano, GP; Valdivieso, JG | 1 |
| Deering, RA; Michrina, CA | 1 |
| Burry, RW | 1 |
| Alberto, P; Barrelet, L; Berchtold, W; Jungi, F; Martz, G; Obrecht, P; Sonntag, R | 1 |
| Bond, AN; Harris, G; Wickramasinghe, SN | 1 |
| Butt, TR; Sreevalsan, T | 1 |
| Beverley, S; Brown, P; Cassin, R; Federspiel, N; Gasser, C; Hill, A; Johnston, R; Mariani, B; Mosse, E; Schimke, RT | 1 |
| Farber, EM; Nall, L | 1 |
| Barsoum, J; Roninson, I; Snapka, R; Varshavsky, A | 1 |
| Scott, JM; Weir, DG | 1 |
| Dardick, I; Dubsky, M; Kiss, G; Setterfield, G; Sheinin, R | 1 |
| Bellamy, AS; Hill, BT | 1 |
| Snapka, RM; Varshavsky, A | 1 |
| Chertkov, IL; Drize, NI | 1 |
| Klenow, S | 1 |
| Halprin, KM; Levine, V; Taylor, JR; Woodyard, C | 1 |
| Chłopkiewicz, B; Koziorowska, JH | 1 |
| Brown, PC; Schimke, RT; Tlsty, TD | 1 |
| Cream, JJ; Pole, DS | 1 |
| Lewis, WH; Parfett, CL; Wright, JA | 1 |
| Clarkson, BD; Gee, TS; Mertelsmann, R; Miké, V; Passe, S | 1 |
| Danno, K; Horio, T | 1 |
| de Bast, C; De Coninck, A; Oleffe, J; Van Opdenbosch, L | 1 |
| Schmidt, JD | 1 |
| DeSesso, JM | 1 |
| Moran, RE; Straus, MJ | 1 |
| Adler, GK; Arbiser, JL; Arbiser, ZK; Majzoub, JA; Martinez, C; Rosen, LB | 1 |
| Vokes, EE | 1 |
| Aisner, J; Belani, CP; Conley, B; Gray, W; Hiponia, D; Jacobs, M | 1 |
| Huang, A; Wright, JA | 1 |
| Kietlińska, Z; Sablińska, B; Zieliński, J | 1 |
| Lindelöf, B; Sigurgeirsson, B | 1 |
| Ahlgren, JD; Anderson, N; Kemeny, N; Lokich, JJ | 1 |
| Harrison, PE; Menter, A; Morris, LF; Phillips, CM; Sander, HM | 1 |
| Ahluwalia, GS; Gao, WY; Johns, DG; Mitsuya, H | 1 |
| Dräger, AM; Huijgens, PC; Schuurhuis, GJ; Teule, GJ; van Leeuwen-Stok, AE; Visser-Platier, AW | 1 |
| Bjerring, P; Heickendorff, L; Zachariae, H | 1 |
| Collins, MK; López-Rivas, A; Oliver, FJ | 1 |
| Grillot, DA; Nuñez, G; Simonian, PL | 1 |
| Fan, H; Huang, A; Taylor, WR; Wright, JA | 1 |
| Azuma, E; Higashigawa, M; Hirayama, M; Hori, H; Ido, M; Kawasaki, H; Sakurai, M | 1 |
| Armstrong, MJ; Bradt, CI; Galloway, SM; Greenwood, SK; Hill, RB; Hilliard, CA; Johnson, TE | 1 |
| Bagshawe, KD; Bower, M; Foskett, M; Holden, L; Newlands, ES; Rustin, GJ; Short, D | 1 |
| Batlle, M; Feliu, E; Fernández-Avilés, F; Gómez Espuch, J; Granada, I; Millá, F; Navarro, JT; Ribera, JM | 1 |
| Hahn, PJ; Nevaldine, BH; Rizwana, R | 1 |
| Akutsu, M; Bai, L; Furukawa, Y; Ichikawa, A; Kano, Y; Kon, K; Suzuki, K; Tsunoda, S | 1 |
| Collins, MK; Gutierrez del Arroyo, A; Palacios, C; Silva, A | 1 |
| Back, DJ; Hoggard, PG; Johnson, MA; Kewn, S; Sales, SD | 1 |
| Akutsu, M; Furukawa, Y; Honma, Y; Kano, Y; Mano, H; Sato, Y; Tsunoda, S | 1 |
| Ebinuma, H; Ishii, H; Nakamoto, N; Nakamura, M; Saito, H; Saito, Y; Takagi, T; Wakabayashi, K | 1 |
| Collins, MK; Leverrier, Y; Low, W; Madsen, C; Olmos-Centenera, G | 1 |
| Battmer, K; Dammann, E; Eder, M; Ganser, A; Hambach, L; Heil, G; Hertenstein, B; Stucki, A | 1 |
| Ait Arkoub, Z; Arnulf, B; Chebbi, F; Fillet, AM; Lefrere, F; Varet, B | 1 |
| Fagny, C; Robberecht, P; Svoboda, M; Vandevelde, M | 1 |
| Belgi, G; Friedmann, PS | 1 |
| Becker, CM; Chitambar, CR; Drexler, HG; Efferth, T; Gebhart, E; Humeny, A; Miyachi, H; Sauerbrey, A; Steinbach, D; Zintl, F | 1 |
| Kormeili, T; Lowe, NJ; Patnaik, R; Rizk, D; Yamauchi, PS | 1 |
| Abdelaal, MA; Gangi, MT; George, BO; Kinsara, AJ | 1 |
| Kimura, S; Kuroda, J; Maekawa, T; Nogawa, M; Ottmann, OG; Sato, K; Segawa, H; Yuasa, T | 1 |
| Armand, JP; Domenge, C; Faivre, S; Gatineau, M; Janot, F; Julieron, M; Luboinski, B; Marti, A; Raymond, E; Rixe, O; Temam, S | 1 |
| Konopka, L; Pawelski, S | 1 |
| Menon, K; Siu, K; Strober, BE | 1 |
| An, RF; Wu, TX; Xue, Y; Zhang, J | 1 |
| Byars, T; Cox, CE; Hartung, C; Judson, MA; Silvestri, J | 1 |
| Balkrishnan, R; Camacho, F; Crane, MM; Feldman, SR; Fleischer, AB; Higgins, KB; Pearce, DJ; Stealey, KH | 1 |
| Mahajan, VK; Ranjan, N; Shanker, V; Sharma, NL; Tegta, GR | 1 |
| Arfi, S; Bachir, D; Fifi-Mah, A; Galacteros, F; Godeau, B; Habibi, A; Lahary, A; Michel, M | 1 |
| Belfort, P; Braga, A; Consonni, M; Delmanto, LR; Maestá, I; Michelin, OC; Rudge, MV | 1 |
| Deng, L; Wu, T; Yan, X; Zhang, J | 1 |
| Mathews, CK | 1 |
| Hazra, SC; Khan, SI; Khondker, L; Mahbub, MS | 1 |
| Deng, L; Lawrie, TA; Wu, T; Zhang, J | 1 |
| Foley, P; Kelly, JB; Strober, BE | 1 |
| Chan, KK; Chu, MM; Ma, Y; Ngan, HY; Tse, KY | 1 |
| Chang, CL; Chen, JH; Chen, TM; Lai, MT; Lee, FP; Lin, KC; Wu, CC; Wu, SY; Yen, YC; Yuan, KS | 1 |
| Lim, YL; Toh, JJ; Yew, YW | 1 |
| Fischer, AS; Kersh, AE; Rosenbach, M; Shields, BE; Torre, EA; Xu, X | 1 |
| Errani, C; Mavrogenis, AF; Takahama, T; Tanaka, Y; Tsukamoto, S | 1 |
| Guan, Z; Li, S; Liang, Y; Niu, B; Wang, J; Wang, X; Yang, A; Yu, J; Zhu, Z | 1 |
| Kato, M; Kikuchi, K; Sakamoto, K; Sako, M; Shioda, Y; Takimoto, T | 1 |
56 review(s) available for hydroxyurea and methotrexate
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Current concepts of chemotherapy combined with other modalities for head and neck cancer.
Topics: Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Hydroxyurea; Immunotherapy; Laryngeal Neoplasms; Leucovorin; Methotrexate; Neoplasm Metastasis; Neoplasms; Radiotherapy; Vinblastine | 1975 |
The integration of chemotherapy into a combined modality approached to cancer therapy. V. Squamous cell cancer of the head and neck.
Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Administration Schedule; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Laryngeal Neoplasms; Leucovorin; Lip Neoplasms; Lymphatic Metastasis; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Tongue Neoplasms | 1975 |
Iatrogenic complications of dermatologic therapy. Primum non nocere.
Topics: Adrenal Cortex Hormones; Azathioprine; Cryosurgery; Cyclophosphamide; Electrosurgery; Erythromycin; Hexachlorocyclohexane; Humans; Hydroxyurea; Iatrogenic Disease; Methotrexate; Podophyllin; Radiotherapy; Skin Diseases; Tetracycline; Ultraviolet Therapy | 1979 |
Psoriasis: current concepts in management.
Topics: Administration, Topical; Adrenal Cortex Hormones; Age Factors; Anthralin; Ficusin; Glycogen; Hair; Humans; Hydroxyurea; Methotrexate; Mitosis; Mucous Membrane; Nails; Psoriasis; Skin; Tars; Tretinoin; Ultraviolet Therapy | 1977 |
The effects of cancer chemotherapeutic agents on normal hematopoietic precursor cells: a review.
Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Asparaginase; Benzamides; Busulfan; Carmustine; Cisplatin; Cyclophosphamide; Cytarabine; Drug Evaluation, Preclinical; Erythrocytes; Fluorouracil; Hematopoietic Stem Cells; Humans; Hydroxyurea; Lomustine; Methotrexate; Nitrogen Mustard Compounds; Spleen; Vinca Alkaloids | 1976 |
On the nature of hereditable variation in cultured somatic cells.
Topics: Amanitins; Azaguanine; Bromodeoxyuridine; Cell Line; Cells, Cultured; Chromosomes; Colchicine; Cycloheximide; Diploidy; Drug Resistance; Genes; Genes, Lethal; Genes, Recessive; Genetic Variation; Hybrid Cells; Hydroxyurea; Immunoglobulins; Lectins; Methotrexate; Mutation; Ouabain; Phenotype; Polyploidy; Temperature | 1976 |
Chronic granulocytic leukemia.
Topics: Alkaline Phosphatase; Blood Transfusion; Busulfan; Chromosomes, Human, 21-22 and Y; Humans; Hydroxyurea; Immunotherapy; Leukemia, Myeloid; Leukocytes; Methotrexate; Prednisone; Splenectomy; Vincristine; Vitamin B 12 | 1976 |
An appraisal of current systemic chemotherapy for psoriasis.
Topics: Alkylating Agents; Antimetabolites, Antineoplastic; Antineoplastic Agents; Azauridine; Cell Division; Female; Humans; Hydroxyurea; Kinetics; Methotrexate; Methoxsalen; Mycophenolic Acid; Psoriasis; Ultraviolet Therapy | 1976 |
Psoriasis: a review. II.
Topics: Adrenal Cortex Hormones; Anthralin; Azathioprine; Azauridine; Fluorouracil; Humans; Hydroxyurea; Lomustine; Mechlorethamine; Methotrexate; Psoriasis; Tars; Tretinoin; Ultraviolet Therapy | 1975 |
Chemotherapy of psoriasis.
Topics: Azauridine; Central Nervous System; Digestive System; Hematopoietic System; Humans; Hydroxyurea; Liver; Methotrexate; Mycophenolic Acid; Psoriasis | 1975 |
Guidelines for management of patients with psoriasis. Workshop of the Research Unit of the Royal College of Physicians of London; Department of Dermatology, University of Glasgow; British Association of Dermatologists.
Topics: Adrenal Cortex Hormones; Azathioprine; Cyclosporins; Humans; Hydroxyurea; Methotrexate; Phototherapy; Psoriasis; Retinoids; Skin | 1991 |
Combination of chemotherapy with radiotherapy: review of previous studies and new perspectives.
Topics: Antineoplastic Agents; Bleomycin; Cisplatin; Combined Modality Therapy; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Methotrexate; Radiation-Sensitizing Agents | 1985 |
Purine metabolism as a target for leukemia chemotherapy.
Topics: Antineoplastic Agents; Drugs, Investigational; Humans; Hydroxyurea; Leukemia; Mercaptopurine; Methotrexate; Pentostatin; Purines; Thioguanine | 1989 |
[Chemotherapy of prostatic cancer].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Dacarbazine; Diethylstilbestrol; Doxorubicin; Estramustine; Fluorouracil; Humans; Hydroxyurea; Male; Melphalan; Methotrexate; Mitomycin; Mitomycins; Prednisolone; Procarbazine; Prostatic Neoplasms; Streptozocin; Vincristine | 1985 |
Chemotherapy of primary brain tumors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Brain Stem; Child; Eflornithine; Ependymoma; Fluorouracil; Glioblastoma; Humans; Hydroxyurea; Lomustine; Medulloblastoma; Methotrexate; Mitoguazone; Mitolactol; Neoplasm Recurrence, Local; Ornithine; Prednisone; Risk; Thioguanine; Vincristine | 1985 |
Principles of brain tumor chemotherapy.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Carbon Radioisotopes; Carmustine; Cell Line; Cisplatin; Dose-Response Relationship, Drug; Drug Resistance; Fluorouracil; Glioma; Humans; Hydroxyurea; Infusions, Intra-Arterial; Karyotyping; Kinetics; Mannitol; Methotrexate; Podophyllotoxin; Procarbazine; Rats; Tumor Stem Cell Assay | 1986 |
Psoriasis.
Topics: Etretinate; Humans; Hydroxyurea; Methotrexate; Psoriasis; PUVA Therapy; Skin; Steroids; Ultraviolet Therapy | 1986 |
Chemotherapy of brain tumors.
Topics: Adult; Antineoplastic Agents; Azaguanine; Bleomycin; Brain Neoplasms; Child; Cyclophosphamide; Drug Synergism; Fluorouracil; Glioblastoma; Glioma; Humans; Hydroxyurea; Medulloblastoma; Methotrexate; Nitrogen Mustard Compounds; Nitrosourea Compounds; Plicamycin; Procarbazine; Streptonigrin; Vinblastine; Vincristine | 1972 |
Drug reactions. XXIV. Cutaneous reactions to cytostatic agents.
Topics: Alopecia; Aminopterin; Antineoplastic Agents; Asparaginase; Azathioprine; Bleomycin; Busulfan; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug Eruptions; Erythema; Fluorouracil; Gynecomastia; Humans; Hydroxyurea; Methotrexate; Photosensitivity Disorders; Pigmentation Disorders; Radiation Injuries; Stomatitis; Vinblastine | 1974 |
Immunosuppressive and cytotoxic drugs in dermatology.
Topics: Animals; Antineoplastic Agents; Azathioprine; Azauridine; Bleomycin; Chlorambucil; Cyclophosphamide; Cytarabine; Dactinomycin; Humans; Hydroxyurea; Immunosuppressive Agents; Mercaptopurine; Methotrexate; Procarbazine; Skin Diseases; Skin Neoplasms; Vinblastine; Vincristine | 1974 |
Solid tumor chemotherapy: What have we to offer.
Topics: Adult; Antineoplastic Agents; Child; Cyclophosphamide; Dactinomycin; Floxuridine; Fluorouracil; Humans; Hydroxyurea; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Palliative Care; Thiotepa; Time Factors; Vincristine | 1970 |
[Some developments in psoriasis research abroad].
Topics: Aza Compounds; Female; Humans; Hydroxyurea; Male; Mechlorethamine; Methotrexate; Psoriasis; Uridine | 1974 |
Synchronization of mammalian cells with respect to the mitotic cycle.
Topics: Animals; Antineoplastic Agents; Autoradiography; Calcium; Carbon Isotopes; Cattle; Cell Count; Cell Differentiation; Cell Line; Cells; Cells, Cultured; Centrifugation, Density Gradient; Clone Cells; Cold Temperature; Cricetinae; Culture Techniques; DNA; Female; Floxuridine; Guinea Pigs; HeLa Cells; Humans; Hydroxyurea; Iodine Isotopes; Kinetics; L Cells; Liver; Methods; Methotrexate; Mice; Mitosis; Ovary; RNA; Statistics as Topic; Thymidine; Time Factors; Tritium | 1971 |
Monochemotherapy of bronchogenic carcinoma withs special reference to cell type.
Topics: Adenocarcinoma; Alkylating Agents; Antineoplastic Agents; Carcinoma, Bronchogenic; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Floxuridine; Humans; Hydroxyurea; Lung Neoplasms; Mechlorethamine; Methotrexate; Mitomycins; Nitrosourea Compounds; Plicamycin; Porfiromycin; Procarbazine; Streptonigrin; Thiotepa; Vinblastine | 1973 |
Antimetabolites and psoriasis.
Topics: Adrenal Cortex Hormones; Animals; Antimetabolites; Arsenic; Humans; Hydroxyurea; Methotrexate; Mice; Neoplasms; Nucleic Acids; Protein Biosynthesis; Psoriasis; Time Factors; Ultraviolet Rays | 1972 |
Single and combination nonhormonal chemotherapy in breast cancer.
Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Cyclophosphamide; Drug Synergism; Female; Fluorouracil; Humans; Hydroxyurea; Melphalan; Menopause; Methotrexate; Mice; Vinblastine; Vincristine | 1972 |
Psoriasis.
Topics: Administration, Topical; Adolescent; Adrenal Cortex Hormones; Adult; Antimetabolites; Child; Female; Humans; Hydroxyurea; Hyperplasia; Injections, Intramuscular; Injections, Intravenous; Keratosis; Male; Methotrexate; Psoriasis; Psychophysiologic Disorders; Tars; Ultraviolet Therapy | 1973 |
[Immunosuppressive drugs in the treatment of diseases belonging to the psoriasis group].
Topics: Administration, Oral; Adrenal Cortex Hormones; Autoantibodies; Humans; Hydroxyurea; Immunosuppressive Agents; Injections, Intramuscular; Injections, Intravenous; Liver; Male; Methotrexate; Psoriasis; Skin; Spermatogenesis | 1974 |
Psoriasis.
Topics: Administration, Topical; Anti-Inflammatory Agents; Antimetabolites; Aza Compounds; Glucocorticoids; Humans; Hydroxyurea; Methotrexate; Psoriasis; Salicylates; Tars; Uridine | 1974 |
Chemotherapy and the life cycle of leukaemic cells. A comparison between the growth characteristics of human acute leukaemia and the murine leukaemia L 1210.
Topics: Anilides; Animals; Cell Division; Cyclophosphamide; Cytarabine; DNA, Neoplasm; Fluorouracil; Humans; Hydroxyurea; In Vitro Techniques; Leukemia; Leukemia L1210; Leukemia, Lymphoid; Mechlorethamine; Mercaptopurine; Methotrexate; Mice; Mitosis; Nitroso Compounds; Prednisone; Thymidine; Time Factors; Tritium; Vinblastine; Vincristine | 1969 |
[New principles of treatment in acute leukemia].
Topics: Adolescent; Adult; Antineoplastic Agents; Central Nervous System Diseases; Child; Cyclophosphamide; Cytarabine; Female; Guanidines; Humans; Hydroxyurea; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukopenia; Male; Mercaptopurine; Methotrexate; Middle Aged; Nitroso Compounds; Prednisone; Thrombocytopenia; Urea; Uric Acid; Vincristine | 1970 |
[Cytostatic drugs in the therapy of psoriasis].
Topics: Alkylating Agents; Aminopterin; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Humans; Hydroxyurea; Methotrexate; Podophyllin; Psoriasis; Purines; Pyrimidines; Skin; Vinblastine; Vincristine | 1971 |
Chemotherapy for squamous cell carcinoma of the head and neck: a progress report.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Mechlorethamine; Mercaptopurine; Methotrexate; Procarbazine; Vinblastine | 1980 |
Changing role of chemotherapy in treatment of head and neck cancer.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Methotrexate; Recurrence | 1982 |
Chronic granulocytic leukemia.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Busulfan; Chromosomes, Human, 21-22 and Y; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Hydroxyurea; Leukapheresis; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Palliative Care; Prednisolone; Prednisone; Thioguanine; Vincristine | 1984 |
Gene amplification and drug resistance in cultured animal cells.
Topics: Animals; Biological Transport; Cell Cycle; Cell Separation; Cells, Cultured; Cricetinae; DNA; DNA Replication; Drug Resistance; Female; Flow Cytometry; Gene Amplification; Hydroxyurea; Mammals; Methotrexate; Tetrahydrofolate Dehydrogenase; Ultraviolet Rays | 1984 |
Psoriasis. A review of recent advances in treatment.
Topics: Administration, Topical; Anthralin; Anti-Inflammatory Agents; Coal Tar; Glucocorticoids; Humans; Hydroxyurea; Hyperthermia, Induced; Methotrexate; Phototherapy; Psoriasis; PUVA Therapy; Renal Dialysis; Retinoids | 1984 |
Acquisition and loss of amplified genes: dramatic effects of hormones, tumor promoters and cytotoxic drugs.
Topics: Animals; Antineoplastic Agents; Base Sequence; Carcinogens; DNA; DNA Replication; Drug Resistance; Gene Amplification; Hormones; Humans; Hydroxyurea; Insulin; Methotrexate; Mice; Mitogens; Tetradecanoylphorbol Acetate; Tetrahydrofolate Dehydrogenase | 1983 |
Drug-induced megaloblastic change.
Topics: Cyclophosphamide; Cytarabine; DNA; Erythrocytes, Abnormal; Floxuridine; Fluorouracil; Folic Acid Antagonists; Humans; Hydroxyurea; Megaloblasts; Methotrexate; Phenytoin; Pyrimethamine; Ribonucleotides; Thymidine Monophosphate; Thymidylate Synthase; Triamterene; Trimethoprim | 1980 |
Psoriasis and its treatment.
Topics: Administration, Topical; Adrenal Cortex Hormones; Anthralin; Humans; Hydroxyurea; Methotrexate; Middle Aged; Psoriasis; PUVA Therapy; Razoxane | 1981 |
Somatic cell genetics: a review of drug resistance, lectin resistance and gene transfer in mammalian cells in culture.
Topics: Amanitins; Animals; Cell Line; Chromosomes; Cloning, Molecular; Colchicine; DNA, Recombinant; Drug Resistance; Genes; Humans; Hybrid Cells; Hydroxyurea; Lectins; Methotrexate; Mutation; Ouabain; Purines; Pyrimidines; Transformation, Genetic | 1980 |
International Commission for Protection against Environmental Mutagens and Carcinogens. ICPEMC publication no. 6: do treatments available for psoriasis patients carry a genetic or carcinogenic risk?
Topics: Anthralin; Azathioprine; Carcinogens; Coal Tar; Humans; Hydroxyurea; Methotrexate; Mutagenicity Tests; Mutagens; Mutation; Probability; Psoriasis; PUVA Therapy; Risk; Salmonella typhimurium | 1981 |
Fluorouracil modulation in head and neck cancer.
Topics: Allopurinol; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Immunologic Factors; Interferons; Leucovorin; Methotrexate | 1993 |
Combined modalities in the treatment of head and neck cancers.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Clinical Trials as Topic; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Hydroxyurea; Methotrexate; Paclitaxel; Platinum Compounds | 1995 |
Recent advances in the treatment of advanced colorectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Colorectal Neoplasms; Drug Administration Schedule; Drug Interactions; Floxuridine; Fluorouracil; Hepatic Artery; Humans; Hydroxyurea; Infusions, Intra-Arterial; Leucovorin; Methotrexate; Neoplasm Staging; Phosphonoacetic Acid; Prospective Studies; Randomized Controlled Trials as Topic | 1993 |
Donor cell-derived acute myeloid leukemia developing 14 months after matched unrelated bone marrow transplantation for chronic myeloid leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Bone Marrow Transplantation; Combined Modality Therapy; Cyclosporine; Cystitis; Cytarabine; Cytomegalovirus Infections; DNA, Neoplasm; Female; Foscarnet; Ganciclovir; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Histocompatibility; Humans; Hydroxyurea; Immunosuppressive Agents; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Methotrexate; Mitoxantrone; Neoplasms, Second Primary; Prednisolone; Prostaglandins; Remission Induction; Topotecan; Transplantation Conditioning; Transplantation, Homologous; Vidarabine; Whole-Body Irradiation | 2001 |
Traditional therapies: glucocorticoids, azathioprine, methotrexate, hydroxyurea.
Topics: Azathioprine; Dermatologic Agents; Glucocorticoids; Humans; Hydroxyurea; Immunosuppressive Agents; Methotrexate; Skin Diseases | 2002 |
Current systemic therapies for psoriasis: where are we now?
Topics: Acitretin; Antineoplastic Agents; Cyclosporine; Dermatologic Agents; Drug Therapy, Combination; Humans; Hydroxyurea; Keratolytic Agents; Methotrexate; Psoriasis; Remission Induction | 2003 |
Idiopathic hypereosinophilic syndrome: a report of four cases in Arabs, and a review of the literature.
Topics: Adult; Anti-Inflammatory Agents; Arabs; Female; Humans; Hydroxyurea; Hypereosinophilic Syndrome; Interferon-alpha; Male; Methotrexate; Middle Aged; Prednisolone | 2001 |
Conventional systemic agents for psoriasis. A systematic review.
Topics: Acitretin; Clinical Trials as Topic; Cyclosporine; Drug Therapy, Combination; Evidence-Based Medicine; Humans; Hydroxyurea; Immunosuppressive Agents; Methotrexate; Practice Guidelines as Topic; Psoriasis; Thioguanine; Treatment Outcome | 2006 |
Combination chemotherapy for high-risk gestational trophoblastic tumour.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Hydroxyurea; Leucovorin; Methotrexate; Pregnancy; Trophoblastic Tumor, Placental Site; Vincristine | 2006 |
Combination chemotherapy for high-risk gestational trophoblastic tumour.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Hydroxyurea; Melphalan; Methotrexate; Pregnancy; Trophoblastic Tumor, Placental Site; Vincristine | 2009 |
Combination chemotherapy for primary treatment of high-risk gestational trophoblastic tumour.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dactinomycin; Doxorubicin; Early Termination of Clinical Trials; Female; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Hydroxyurea; Leucovorin; Melphalan; Methotrexate; Pregnancy; Trophoblastic Tumor, Placental Site; Vincristine | 2013 |
Current and future oral systemic therapies for psoriasis.
Topics: Acitretin; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites; Cyclosporine; Fumarates; Humans; Hydroxyurea; Immunosuppressive Agents; Isoxazoles; Keratolytic Agents; Leflunomide; Methotrexate; Mycophenolic Acid; Piperidines; Protein Kinase Inhibitors; Psoriasis; Pyrimidines; Pyrroles; Sulfasalazine; Thalidomide; Thioguanine | 2015 |
Clinical outcomes of medical treatments for progressive desmoid tumors following active surveillance: a systematic review.
Topics: Doxorubicin; Fibromatosis, Aggressive; Humans; Hydroxyurea; Imatinib Mesylate; Methotrexate; Sorafenib; Vinorelbine; Watchful Waiting | 2023 |
18 trial(s) available for hydroxyurea and methotrexate
| Article | Year |
|---|---|
[Polychemotherapy of inoperable bronchogenic carcinoma: preliminary results (author's transl)].
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Bronchogenic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Humans; Hydroxyurea; Methotrexate; Quality of Life; Vincristine | 1979 |
Treatment of psoriasis with 6-aminonicotinamide.
Topics: Acid-Base Equilibrium; Administration, Oral; Administration, Topical; Adult; Aged; Amines; Biopsy; Clinical Trials as Topic; Female; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Niacinamide; Nicotinic Acids; Psoriasis; Skin; Solvents | 1975 |
Combination chemotherapy of advanced lung cancer: a randomized trial.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Leukopenia; Lomustine; Lung Neoplasms; Male; Mechlorethamine; Methotrexate; Middle Aged; Procarbazine; Thrombocytopenia; Vincristine | 1976 |
Favorable long-term survival following induction chemotherapy with cisplatin, fluorouracil, and leucovorin and concomitant chemoradiotherapy for locally advanced head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Leucovorin; Male; Methotrexate; Middle Aged; Radiography; Time Factors; Treatment Outcome | 1992 |
[Chemo-radiotherapy in advanced head and neck tumors. Personal experience].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cobalt Radioisotopes; Combined Modality Therapy; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hydroxyurea; Methotrexate; Middle Aged; Radioisotope Teletherapy; Radiotherapy Dosage; Time Factors | 1992 |
A randomized study of methotrexate, bleomycin, hydroxyurea with versus without cisplatin in patients with previously untreated and recurrent squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Dose-Response Relationship, Drug; Female; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Random Allocation | 1987 |
CBVPM/AVBP versus HCOMLA chemotherapy in non-Hodgkin lymphoma patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Humans; Hydroxyurea; Leucovorin; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Prednisone; Vincristine | 1987 |
A prospective randomized comparison of methotrexate, dactinomycin, and chlorambucil versus methotrexate, dactinomycin, cyclophosphamide, doxorubicin, melphalan, hydroxyurea, and vincristine in "poor prognosis" metastatic gestational trophoblastic disease:
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; Hydroxyurea; Leucovorin; Methotrexate; Multicenter Studies as Topic; Pregnancy; Prospective Studies; Random Allocation; Trophoblastic Neoplasms; Uterine Neoplasms; Vincristine | 1989 |
Treatment of metastatic and recurrent cervix cancer with chemotherapy: a randomised trial comparing hydroxyurea with cisdiamminedichloro-platinum plus methotrexate.
Topics: Actuarial Analysis; Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Female; Humans; Hydroxyurea; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Random Allocation; South Africa; Uterine Cervical Neoplasms | 1986 |
A clinical trial of hydroxyurea for psoriasis.
Topics: Adult; Aged; Drug Eruptions; Drug Hypersensitivity; Female; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Psoriasis | 1972 |
Hydroxyurea. A new treatment for psoriasis.
Topics: Adult; Aged; Biopsy; Blood Cell Count; Clinical Trials as Topic; Female; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Placebos; Psoriasis | 1970 |
Combined radiotherapy and chemotherapy of lymphomas and other cancers.
Topics: Clinical Trials as Topic; Cyclophosphamide; Dactinomycin; Fluorouracil; Follow-Up Studies; Hematopoietic System; Hodgkin Disease; Humans; Hydroxyurea; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Methotrexate; Placebos; Vincristine | 1971 |
Chemotherapy for squamous cell carcinoma of the head and neck: a progress report.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Mechlorethamine; Mercaptopurine; Methotrexate; Procarbazine; Vinblastine | 1980 |
Continuous intravenous infusion combination chemotherapy for head and neck squamous cell carcinoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hydroxyurea; Infusions, Parenteral; Male; Methotrexate; Middle Aged; Neoplasm Staging; Vinblastine | 1984 |
Chemotherapy of small cell carcinoma of the lung: comparison of a cyclic alternative combination with simultaneous combinations of four and seven agents.
Topics: Antineoplastic Agents; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Procarbazine; Vincristine | 1981 |
The effect of thalidomide on corticosteroid-dependent pulmonary sarcoidosis.
Topics: Adrenal Cortex Hormones; Black or African American; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Pilot Projects; Prednisone; Prospective Studies; Quality of Life; Sarcoidosis, Pulmonary; Surveys and Questionnaires; Thalidomide; Time Factors; Treatment Outcome; White People | 2006 |
Methotrexate versus hydroxycarbamide (hydroxyurea) as a weekly dose to treat moderate-to-severe chronic plaque psoriasis: a comparative study.
Topics: Administration, Oral; Adolescent; Adult; Aged; Dermatologic Agents; Drug Administration Schedule; Female; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Psoriasis; Severity of Illness Index; Skin; Treatment Outcome | 2007 |
Comparative efficacy of hydroxyurea and methotrexate in treating psoriasis.
Topics: Adolescent; Adult; Bangladesh; Dermatologic Agents; Female; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Psoriasis; Severity of Illness Index; Treatment Outcome; Young Adult | 2013 |
227 other study(ies) available for hydroxyurea and methotrexate
| Article | Year |
|---|---|
Structure-activity relationships of antineoplastic agents in multidrug resistance.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured | 1990 |
Comparative structure-activity relationships of antifolate triazines inhibiting murine tumor cells sensitive and resistant to methotrexate.
Topics: Animals; Chemical Phenomena; Chemistry, Physical; Chickens; Drug Resistance; Folic Acid Antagonists; Humans; Leukemia L5178; Leukemia, Experimental; Mathematics; Methotrexate; Mice; Structure-Activity Relationship; Triazines | 1984 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Kinetically-based multiple drug treatment for advanced head and neck cancer.
Topics: Antineoplastic Agents; Bleomycin; Doxorubicin; Drug Synergism; Drug Therapy, Combination; Ear Neoplasms; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Hydroxyurea; Laryngeal Neoplasms; Maxillary Neoplasms; Mercaptopurine; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Neoplasms; Tongue Neoplasms; Tonsillar Neoplasms; Vincristine | 1975 |
Enhancing effect by metabolic inhibitors on the killing of tumor cells by antibody and complement.
Topics: Animals; Antibodies, Neoplasm; Antigen-Antibody Reactions; Antineoplastic Agents; Azacitidine; Carcinoma, Hepatocellular; Cells, Cultured; Complement System Proteins; Cyclophosphamide; Cytarabine; Dactinomycin; Doxorubicin; Fluorouracil; Guinea Pigs; Hydroxyurea; Liver Neoplasms; Mercaptopurine; Methotrexate; Mitomycins; Neoplasms, Experimental; Puromycin; Vincristine | 1975 |
Generalized pustular psoriasis. A report on thirteen patients.
Topics: Adrenal Cortex Hormones; Adult; Aged; Anti-Bacterial Agents; Female; Follow-Up Studies; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Prognosis; Psoriasis; Streptococcal Infections | 1976 |
Intravenous bleomycin infusion as a potential syncronizing agent in human disseminated malignancies: a preliminary report.
Topics: Adult; Bleomycin; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Hydroxyurea; Infusions, Parenteral; Lung Neoplasms; Male; Methotrexate; Neoplasms; Urinary Bladder Neoplasms | 1976 |
Hair growth inhibition as a method of screening drugs for local antimitotic activity.
Topics: Animals; Antineoplastic Agents; Bleomycin; Colchicine; Cyclophosphamide; Cytarabine; Drug Evaluation, Preclinical; Fluorouracil; Guinea Pigs; Hair; Hydroxyurea; Injections, Intradermal; Mechlorethamine; Methotrexate; Mitosis; Thiotepa; Vincristine | 1977 |
Chemotherapy for oral malignant disease.
Topics: Antineoplastic Agents; Bleomycin; Drug Therapy, Combination; Fluorouracil; Humans; Hydroxyurea; Injections, Intra-Arterial; Methotrexate; Mouth Neoplasms; Prognosis; Vinblastine | 1979 |
Neutrophil chemotaxis in psoriasis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Chemotaxis, Leukocyte; Child; Cyclic AMP; Cyclic GMP; Epidermis; Ethylenediamines; Female; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Neutrophils; Phosphodiesterase Inhibitors; Psoriasis; Skin; Theophylline | 1979 |
The chemotherapy of urologic cancer.
Topics: Adenocarcinoma; Adult; Aged; Alkylating Agents; Antineoplastic Agents; Doxorubicin; Drug Therapy, Combination; Estradiol; Female; Floxuridine; Fluorouracil; Humans; Hydroxyurea; Kidney Neoplasms; Male; Methotrexate; Middle Aged; Mitomycins; Plicamycin; Prostatic Neoplasms; Testicular Neoplasms; Thiotepa; Urinary Bladder Neoplasms; Urogenital Neoplasms; Vincristine | 1975 |
Isotope-dilution studies of the effects of 5-fluorodeoxyuridine and hydroxyurea on the incorporation of deoxycytidine and thymidine by cultured thymus cells.
Topics: Animals; Cells, Cultured; Cytidine; Deoxyadenosines; Deoxycytidine; Deoxyribonucleosides; DNA Replication; Floxuridine; Hydroxyurea; Methotrexate; Rats; Thymidine; Thymus Gland | 1976 |
The reversible inhibition of myoblast fusion by ethidium bromide (EB).
Topics: Cell Fusion; Cells, Cultured; Chloramphenicol; Cytarabine; DNA; Dose-Response Relationship, Drug; Ethidium; Floxuridine; Hydroxyurea; Methotrexate; Protein Biosynthesis; Rifampin; RNA; Thymidine | 1976 |
Comparison of thymidine, fluorodeoxyuridine, hydroxyurea, and methotrexate blocking at the G1/S phase transition of the cell cycle, studied by replication patterns.
Topics: Amniotic Fluid; Cell Cycle; Cells, Cultured; Chromosomes, Human; DNA Replication; Floxuridine; History, 16th Century; Humans; Hydroxyurea; Interphase; Methotrexate; Skin; Thymidine | 1978 |
Stimulation of human chorionic gonadotropin by JAr line choriocarcinoma after inhibition of DNA synthesis.
Topics: Cell Line; Choriocarcinoma; Chorionic Gonadotropin; Cycloheximide; Cytarabine; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Floxuridine; Humans; Hydroxyurea; Methotrexate; Neoplasm Proteins; Neoplasms, Experimental; Pregnancy; Uterine Neoplasms | 1979 |
Effect of thymidine on poly(ADP-ribosyl)ation in vivo.
Topics: Cell Nucleus; DNA Replication; DNA, Neoplasm; HeLa Cells; Humans; Hydroxyurea; Kinetics; Methotrexate; Niacinamide; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Thymidine | 1979 |
A new combination chemotherapy for resistant trophoblastic disease.
Topics: Adult; Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Drug Resistance; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Leucovorin; Melphalan; Methotrexate; Pregnancy; Trophoblastic Neoplasms; Uterine Neoplasms; Vincristine | 1979 |
[Experience in acceleration and blastic crisis in chronic myelocytic leukemia].
Topics: Adult; Blood Cells; Cell Count; Female; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Splenectomy; Thioguanine | 1978 |
[Splenectomy and polychemotherapy in chronic myelosis].
Topics: Busulfan; Cytarabine; Daunorubicin; Humans; Hydroxyurea; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Mitobronitol; Prognosis; Splenectomy; Vincristine | 1979 |
Enhancement by caffeine of the growth inhibitory effects of antimetabolites in lymphoma L5178Y cells.
Topics: Antimetabolites; Caffeine; Cell Division; Cells, Cultured; Deoxyadenosines; Drug Synergism; Hydroxyurea; In Vitro Techniques; Lymphoma; Methotrexate; Methylthioinosine; Mycophenolic Acid; Neoplasms, Experimental; Time Factors | 1977 |
Philadelphia-chromosome-positive pre-B-cell leukemia presenting as blast crisis of chronic myelogenous leukemia.
Topics: B-Lymphocytes; Cell Transformation, Neoplastic; Child; Chromosomes, Human, 21-22 and Y; Humans; Hydroxyurea; Leukemia; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Phenotype; Prednisone; Time Factors; Vincristine | 1979 |
Prolongation of rat cardiac allograft survival by donor pretreatment. Impact of dose and timing of drug administration.
Topics: Animals; Busulfan; Cyclophosphamide; Graft Survival; Heart; Heart Transplantation; Hydroxyurea; Lethal Dose 50; Methotrexate; Procarbazine; Rats; Time Factors; Tissue Donors; Transplantation, Homologous | 1979 |
Successful treatment of juvenile chronic granulocytic leukemia with marrow transplantation.
Topics: Bone Marrow Transplantation; Busulfan; Child, Preschool; Cyclophosphamide; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Transplantation, Homologous | 1979 |
Engraftment of RH-positive marrow in a recipient with RH antibody.
Topics: Acute Disease; Adult; Blood Group Incompatibility; Bone Marrow Cells; Bone Marrow Transplantation; Cell Survival; Cyclophosphamide; Cytarabine; Graft Survival; Humans; Hydroxyurea; Injections, Spinal; Isoantibodies; Leukemia, Lymphoid; Male; Methotrexate; Patient Isolators; Rh-Hr Blood-Group System | 1977 |
Bowen's disease and squamous cell carcinoma. Occurrence in a patient with psoriasis after topical, systemic, and PUVA therapy.
Topics: Adult; Carcinoma, Squamous Cell; Coal Tar; Cocarcinogenesis; Glucocorticoids; Humans; Hydroxyurea; Male; Methotrexate; Methoxsalen; Penile Neoplasms; Photochemotherapy; Psoriasis; Skin Neoplasms; Vitamin A | 1979 |
Head and neck neoplasms: outpatient chemotherapy.
Topics: Ambulatory Care; Head and Neck Neoplasms; Humans; Hydroxyurea; Methotrexate | 1979 |
Effect of some cytostatics on the haemopoietic stem cells (CFUs) in blood.
Topics: Animals; Antineoplastic Agents; Blood Cell Count; Colchicine; Colony-Forming Units Assay; Cytarabine; Female; Hematopoietic Stem Cells; Hematopoietic System; Hydroxyurea; Methotrexate; Mice; Vinblastine; Vincristine | 1979 |
Psoriasis: topical and systemic therapy.
Topics: Administration, Topical; Adrenal Cortex Hormones; Anthralin; Coal Tar; Humans; Hydroxyurea; Keratolytic Agents; Methotrexate; Photochemotherapy; Psoriasis | 1979 |
Defective DNA synthesis in megaloblastic anaemia. Studies employing velocity sedimentation in alkaline sucrose gradients.
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Autoradiography; Centrifugation, Density Gradient; DNA Replication; Folic Acid Deficiency; Humans; Hydroxyurea; In Vitro Techniques; Lymphocytes; Methotrexate; Vitamin B 12 Deficiency | 1979 |
When to try antineoplastic agents in psoriasis.
Topics: Antineoplastic Agents; Azauridine; Humans; Hydroxyurea; Kidney Function Tests; Liver Function Tests; Methotrexate; Mycophenolic Acid; Psoriasis | 1977 |
[Cytostatic therapy of psoriasis].
Topics: Antineoplastic Agents; Azauridine; Humans; Hydroxyurea; Methotrexate; Psoriasis | 1979 |
Differential distribution of antitumor agents in primary and secondary tumors.
Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Carcinoma 256, Walker; Cyclophosphamide; Daunorubicin; Doxorubicin; Female; Hydroxyurea; Lung Neoplasms; Lymphatic Metastasis; Male; Mercaptopurine; Methotrexate; Methylnitrosourea; Mice; Neoplasm Metastasis; Neoplasms, Experimental; Rats; Sarcoma, Experimental | 1977 |
Effects of antipsoriasis drugs and metabolic inhibitors on the growth of epidermal cells in culture.
Topics: Animals; Anthralin; Antimetabolites; Azauridine; Cell Division; Cells, Cultured; Cycloheximide; Cytarabine; Dactinomycin; Daunorubicin; Guinea Pigs; Hydroxyurea; Methotrexate; Mycophenolic Acid; Psoriasis; Puromycin; Skin | 1978 |
[Resistance testing and chemotherapy results of bronchial tumours (author's transl)].
Topics: Bronchial Neoplasms; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Resistance; Fluorouracil; Humans; Hydroxyurea; Methotrexate; Prognosis; Remission, Spontaneous; Vincristine | 1978 |
[Effectiveness of cytostatic agents on the psoriatic epidermal cell (author's transl)].
Topics: Antineoplastic Agents; Female; Humans; Hydroxyurea; Male; Methotrexate; Psoriasis | 1978 |
Further experience with chemotherapy in the Dunning prostatic adenocarcinoma.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Asparaginase; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Hybridization, Genetic; Hydroxyurea; Lomustine; Male; Methotrexate; Neoplasms, Experimental; Platinum; Prostatic Neoplasms; Rats | 1978 |
Psoriasis: clinical aspects and management.
Topics: Administration, Topical; Age Factors; Azauridine; Fluorouracil; Humans; Hydroxyurea; Mechlorethamine; Methotrexate; Methoxsalen; Nitrosourea Compounds; Psoriasis; Thiotepa; Triamcinolone Acetonide | 1976 |
Choline antagonism of methotrexate liver toxicity in the rat.
Topics: Animals; Chemical and Drug Induced Liver Injury; Choline; Hydroxyurea; Liver; Liver Diseases; Male; Methotrexate; Methylation; Rats; Triglycerides | 1977 |
Drug-induced limb dysplasias in fetal rabbits.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Acetazolamide; Animals; Ectoderm; Extremities; Female; Hydroxyurea; Limb Deformities, Congenital; Litter Size; Maternal-Fetal Exchange; Mesoderm; Methotrexate; Pregnancy; Rabbits | 1977 |
The true heartbreaks of psoriasis.
Topics: Humans; Hydroxyurea; Methotrexate; Psoriasis; Ultraviolet Therapy | 1977 |
DNA synthesis in isolated lymphocyte nuclei. Effects of megaloblastic anaemia due to folate or vitamin B-12 deficiency or antimetabolite drugs.
Topics: Adenosine Triphosphate; Adult; Aged; Anemia, Macrocytic; Anemia, Megaloblastic; Cell Nucleus; Cytarabine; DNA; DNA Replication; DNA-Directed DNA Polymerase; Ethylmaleimide; Female; Fluorouracil; Folic Acid Deficiency; Humans; Hydroxyurea; Kinetics; Lectins; Lymphocyte Activation; Lymphocytes; Male; Methotrexate; Middle Aged; Thymine Nucleotides; Vitamin B 12 Deficiency | 1977 |
Toxicity of antitumor agents on hemopoietic colony forming cells.
Topics: Animals; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Cyclophosphamide; Cytarabine; Female; Femur; Hematopoietic Stem Cells; Hydroxyurea; Mercaptopurine; Methotrexate; Mice; Mice, Inbred Strains; Spleen | 1976 |
Chemotherapy of psoriasis: ten years of experience.
Topics: Azauridine; Humans; Hydroxyurea; Methotrexate; Psoriasis; Retrospective Studies | 1976 |
Systemic chemotherapy for psoriasis: a national survey.
Topics: Adult; Azauridine; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Drug Utilization; Female; Humans; Hydroxyurea; Liver; Methotrexate; Neoplasms; Psoriasis; Thrombophlebitis | 1976 |
Proliferation rate of haemopoietic stem cells after damage by several cytostatic agents.
Topics: Animals; Cell Division; Colchicine; Cytarabine; Dose-Response Relationship, Radiation; Female; Hematopoietic Stem Cells; Hydroxyurea; Methotrexate; Mice | 1976 |
[Immunosuppressive agents in the treatment of psoriasis].
Topics: Azauridine; Cyclophosphamide; Drug Evaluation; Humans; Hydroxyurea; Immunosuppressive Agents; Methotrexate; Psoriasis | 1976 |
[Our therapeutic experiences with psoriasis in Morocco].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Child; Drug Therapy, Combination; Female; Fluocinonide; Heliotherapy; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Morocco; Placebos; Podophyllin; Psoriasis; Psychophysiologic Disorders; Seasons; Sleep; Tars | 1976 |
Treatment of therapy-resistant acute myeloid leukaemia with 7 and 8 cytostatics.
Topics: Adolescent; Adult; Aged; Candidiasis; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Resistance; Drug Therapy, Combination; Esophagitis, Peptic; Female; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Leukocyte Count; Leukopenia; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisolone; Stomach Ulcer; Thioguanine; Vincristine | 1975 |
Treatment of acute leukemia in adults.
Topics: Adolescent; Adult; Aged; Asparaginase; Carmustine; Child; Cytarabine; Daunorubicin; Female; Humans; Hydroxyurea; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Remission, Spontaneous; Thioguanine; Vincristine | 1975 |
Non-Hodgkin's lymphoma in children: results of treatment with LSA2-L2 protocol.
Topics: Adolescent; Antineoplastic Agents; Asparaginase; Bone Neoplasms; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Lymph Nodes; Lymphoma; Male; Mediastinal Neoplasms; Methotrexate; Nasopharyngeal Neoplasms; Ovarian Neoplasms; Skin Neoplasms; Stomach Neoplasms; Thioguanine; Vincristine | 1975 |
Megaloblastic anemia in the management of severe psoriasis.
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Female; Humans; Hydroxyurea; Methotrexate; Middle Aged; Psoriasis | 1975 |
Chemotherapy of acute lymphoblastic leukemia in children.
Topics: Adolescent; Antineoplastic Agents; Asparaginase; Central Nervous System Diseases; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Infant; Injections, Spinal; Leukemia, Lymphoid; Male; Methotrexate; Nitrosourea Compounds; Prednisone; Remission, Spontaneous; Thioguanine; Vincristine | 1976 |
[Possibilities and limits of pre-therapeutic neoplasm sensitivity cytostatics tests under short-term conditions].
Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Cricetinae; Cyclophosphamide; Dactinomycin; Daunorubicin; Disease Models, Animal; DNA, Neoplasm; Doxorubicin; Drug Evaluation, Preclinical; Female; Fluorouracil; Humans; Hydroxyurea; Male; Methotrexate; Mice; Procarbazine; Rats; RNA, Neoplasm; Time Factors; Triaziquone; Vincristine | 1975 |
Eosinophilic leukemia. Remission with vincristine and hydroxyurea.
Topics: Adult; Drug Administration Schedule; Drug Therapy, Combination; Eosinophils; Humans; Hydroxyurea; Leukemia; Male; Methotrexate; Prednisone; Remission, Spontaneous; Vincristine | 1975 |
The lethal actions of antitumor agents in proliferating cell systems in vivo.
Topics: Animals; Antineoplastic Agents; Cell Survival; Cytarabine; DNA; DNA Replication; Epithelial Cells; Epithelium; Hydroxyurea; Intestinal Mucosa; Intestine, Small; Lysosomes; Methotrexate; Mice; Mitosis; Necrosis; Poly I-C; RNA; Vacuoles | 1975 |
Non-Hodgkin's lymphoma in children.
Topics: Adolescent; Asparaginase; Bone Marrow; Brain Neoplasms; Carmustine; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Hydroxyurea; Lymphoma; Male; Methotrexate; Neoplasm Metastasis; Nitrogen Mustard Compounds; Peripheral Nervous System Neoplasms; Prednisone; Prognosis; Thioguanine; Vincristine | 1975 |
Non-Hodgkin's lymphoma in children. A comparative study of two modalities of therapy.
Topics: Adolescent; Antineoplastic Agents; Asparaginase; Carmustine; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Lymphoma; Male; Mercaptopurine; Methotrexate; Neoplasm Metastasis; Prednisone; Thioguanine; Vinblastine; Vincristine | 1976 |
Cell kinetics and programmed chemotherapy for gynecologic cancer. I. Squamous-cell carcinoma.
Topics: Carcinoma, Squamous Cell; Cell Division; DNA, Neoplasm; Female; Genital Neoplasms, Female; Humans; Hydroxyurea; Kinetics; Methotrexate; Uterine Cervical Neoplasms; Vaginal Neoplasms; Vincristine; Vulvar Neoplasms | 1976 |
Importance of pyrimidine nucleotide salvage pathways for DNA synthesis in skin.
Topics: Animals; Animals, Newborn; Azauridine; Cytidine; DNA; Hydroxyurea; Liver; Methotrexate; Mice; Orotic Acid; Pyrimidine Nucleotides; Rabbits; RNA; Skin; Thymidine; Time Factors; Uridine | 1976 |
Differential susceptibility to carcinogen-induced amplification of SV40 and dhfr sequences in SV40-transformed human keratinocytes.
Topics: Aphidicolin; Carcinogens; Cell Line, Transformed; Cell Transformation, Viral; Cycloheximide; Drug Resistance; Gene Amplification; Genes, Viral; Humans; Hydroxyurea; Keratinocytes; Methotrexate; Mitomycin; Proto-Oncogene Mas; Simian virus 40; Tetrahydrofolate Dehydrogenase; Time Factors; Ultraviolet Rays; X-Rays | 1992 |
Non-aggressive therapy for chronic myeloid leukaemia in blastic transformation.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Child; Cytarabine; Daunorubicin; Doxorubicin; Female; Humans; Hydroxyurea; Leukemia; Leukemia, Myeloid, Chronic-Phase; Male; Methotrexate; Middle Aged; Remission Induction; Thioguanine; Vincristine | 1992 |
Hydroxyurea accelerates loss of extrachromosomally amplified genes from tumor cells.
Topics: Aspartate Carbamoyltransferase; Aspartic Acid; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Carcinoma, Squamous Cell; Cell Division; Chromosome Deletion; Dihydroorotase; DNA Replication; Drug Resistance; Gene Amplification; Humans; Hydroxyurea; Methotrexate; Multienzyme Complexes; Phosphonoacetic Acid; Plasmids; Tumor Cells, Cultured; Vinblastine | 1991 |
Comparison of the effect of hydroxyurea and methotrexate on DNA fragmentation at various reaction conditions.
Topics: DNA; DNA Damage; Hydroxyurea; Methotrexate | 1991 |
Several new approaches to improvement of alpha interferon therapy in chronic myelogenous leukaemia.
Topics: Animals; Combined Modality Therapy; Genetic Therapy; Humans; Hydroxyurea; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Methotrexate; Mice; RNA, Messenger; RNA, Neoplasm | 1991 |
Stimulation of dihydrofolate reductase promoter activity by antimetabolic drugs.
Topics: Animals; Aphidicolin; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Floxuridine; Gene Expression; Hydroxyurea; In Vitro Techniques; Methotrexate; Promoter Regions, Genetic; Tetrahydrofolate Dehydrogenase; Transcription, Genetic; Transfection | 1991 |
Regulation of gene expression in choriocarcinoma by methotrexate and hydroxyurea.
Topics: Choriocarcinoma; Chorionic Gonadotropin; DNA; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Genes, myc; Humans; Hydroxyurea; Methotrexate; Proteins; RNA, Messenger; Tumor Cells, Cultured | 1991 |
Selective uptake of toxic nucleoside (125IUdR) by resistant cancer.
Topics: Adenocarcinoma; Animals; Cell Line; Choriocarcinoma; Colon; Colonic Neoplasms; Cytarabine; Drug Resistance; Female; Fluorouracil; Humans; Hydroxyurea; Idoxuridine; Iodine Radioisotopes; Male; Methotrexate; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Uterine Neoplasms | 1991 |
Systemic drug therapy for psoriasis. The most critical issues.
Topics: Cyclosporins; Humans; Hydroxyurea; Methotrexate; Psoriasis | 1991 |
Activity profiles of developmental toxicity: design considerations and pilot implementation.
Topics: Animals; Biological Assay; Caffeine; Cyclophosphamide; Data Collection; Databases, Factual; Embryonic and Fetal Development; Ethylenethiourea; Humans; Hydroxyurea; Methotrexate; Mutagenicity Tests; Toxicology | 1991 |
Drug-induced loss of unstably amplified genes.
Topics: Camptothecin; Dose-Response Relationship, Drug; Drug Resistance; Eflornithine; Gene Amplification; Guanazole; Hydroxyurea; Methotrexate; Proflavine; Tetrahydrofolate Dehydrogenase | 1990 |
DNA amplification is rare in normal human cells.
Topics: Breast; Cells, Cultured; Diploidy; DNA; Drug Resistance; Epithelial Cells; Epithelium; Female; Fibroblasts; Gene Amplification; Humans; Hydroxyurea; Immunoblotting; Infant, Newborn; Keratinocytes; Male; Methotrexate | 1990 |
Induction chemotherapy with methotrexate, bleomycin and hydroxyurea with or without cisplatin in advanced squamous cell carcinoma of the head and neck: a study of the Swiss Group for Clinical Cancer Research (SAKK).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Evaluation; Female; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged | 1985 |
Modulation of glycoprotein hormone alpha-subunit levels, alkaline phosphatase activity, and DNA replication by antimetabolites in HeLa cultures.
Topics: Alkaline Phosphatase; Antimetabolites; Butyrates; Butyric Acid; Cytarabine; DNA Replication; DNA, Neoplasm; Glycoprotein Hormones, alpha Subunit; HeLa Cells; Humans; Hydroxyurea; Kinetics; Methotrexate | 1989 |
Malignant melanoma associated with multiple therapies for psoriasis.
Topics: Adrenal Cortex Hormones; Adult; Coal Tar; Humans; Hydroxyurea; Male; Melanoma; Methotrexate; Photochemotherapy; Phototherapy; Psoriasis; Skin Neoplasms | 1989 |
Postcricoid carcinoma: a retrospective study of 13 patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Doxorubicin; Female; Fluorouracil; Humans; Hydroxyurea; Laryngeal Neoplasms; Male; Mercaptopurine; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Retrospective Studies; Vincristine | 1985 |
Ara-CTP metabolism following hydroxyurea or methotrexate treatment in human leukemia cell lines.
Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; Deoxycytidine; Deoxycytosine Nucleotides; Drug Synergism; Humans; Hydroxyurea; Leukemia; Leukemia, Promyelocytic, Acute; Methotrexate; Thymine Nucleotides; Tumor Cells, Cultured | 1989 |
Hydroxyurea, methotrexate and adriblastine can mediate non-enzymatic reduction of nitroblue tetrazolium with NADH which is inhibited by superoxide dismutase.
Topics: Antibiotics, Antineoplastic; Doxorubicin; Free Radicals; Hydroxyurea; Methotrexate; NAD; Nitroblue Tetrazolium; Oxidation-Reduction; Superoxide Dismutase; Superoxides; Tetrazolium Salts | 1987 |
EMA/CO regimen in high-risk gestational trophoblastic tumor (GTT).
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dactinomycin; Doxorubicin; Etoposide; Female; Humans; Hydroxyurea; Methotrexate; Middle Aged; Pregnancy; Pregnancy Complications, Neoplastic; Trophoblastic Neoplasms; Uterine Neoplasms; Vincristine | 1988 |
Comparison of the inhibitory effects of hydroxyurea, 5-fluorodeoxyuridine, 3,4-dihydroxybenzylamine, and methotrexate on human squamous cell carcinoma.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line; Deoxyuracil Nucleotides; Depression, Chemical; DNA Replication; Dopamine; Floxuridine; Humans; Hydroxyurea; Leukemia L1210; Melanoma, Experimental; Methotrexate; Neoplasm Proteins; Thymidylate Synthase | 1987 |
Inhibition of thymidylate synthase in intact L1210 cells by ara-C, daunomycin, hydroxyurea and 3,4-dihydroxybenzylamine.
Topics: Animals; Cytarabine; Daunorubicin; Deoxyuridine; DNA; Dopamine; Floxuridine; Hydroxyurea; Kinetics; Leukemia L1210; Methotrexate; Thymidylate Synthase | 1987 |
Microinjected deoxynucleotides for the study of chemical inhibition of DNA synthesis.
Topics: Animals; Aphidicolin; Autoradiography; Cell Nucleus; Cells, Cultured; Cytarabine; Deoxyribonucleotides; Diterpenes; DNA Replication; Floxuridine; Hydroxyurea; Kinetics; Methotrexate; Trifluridine; Tritium | 1988 |
Modified Bagshawe's regimen in high-risk gestational trophoblastic disease.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Hematopoietic System; Humans; Hydroxyurea; Leucovorin; Methotrexate; Middle Aged; Neoplasm Metastasis; Pregnancy; Risk; Time Factors; Trophoblastic Neoplasms; Uterine Neoplasms; Vincristine | 1986 |
Replication intermediates formed during initiation of DNA synthesis in methotrexate-resistant CHOC 400 cells are enriched for sequences derived from a specific, amplified restriction fragment.
Topics: Animals; Base Sequence; Cell Cycle; Cell Line; Cricetinae; Cricetulus; Cytarabine; DNA; DNA Replication; DNA Restriction Enzymes; Drug Resistance; Female; Gene Amplification; Genes; Hydroxyurea; Kinetics; Methotrexate; Ovary; Tetrahydrofolate Dehydrogenase | 1986 |
Establishment and characterization of two human cell lines with amplified dihydrofolate reductase genes.
Topics: Cell Line; Cell Transformation, Viral; Colchicine; DNA Replication; Drug Resistance; Fibroblasts; Gene Amplification; Humans; Hydroxyurea; Methotrexate; Nucleic Acid Hybridization; Simian virus 40; Tetrahydrofolate Dehydrogenase | 1987 |
Transient inhibition of DNA synthesis results in increased dihydrofolate reductase synthesis and subsequent increased DNA content per cell.
Topics: Animals; Aphidicolin; Cell Cycle; Cell Line; Diterpenes; DNA; DNA Replication; Drug Resistance; Gene Amplification; Hydroxyurea; Interphase; Kinetics; Methotrexate; Tetrahydrofolate Dehydrogenase | 1986 |
Comparison of synchronized Chinese hamster ovary cells obtained by mitotic shake-off, hydroxyurea, aphidicolin, or methotrexate.
Topics: Animals; Aphidicolin; Cell Cycle; Cell Line; Cell Survival; Cricetinae; Cricetulus; Diterpenes; Female; Flow Cytometry; Hydroxyurea; Methotrexate; Mitosis; Ovary | 1987 |
Over-replication of DNA in S phase Chinese hamster ovary cells after DNA synthesis inhibition.
Topics: Animals; Aphidicolin; Base Sequence; Bromodeoxyuridine; Cell Line; Cell Survival; Cricetinae; Cricetulus; Diterpenes; DNA; DNA Replication; Drug Resistance; Female; Flow Cytometry; Gene Amplification; Hydroxyurea; Interphase; Methotrexate; Ovary; Ultraviolet Rays | 1987 |
Elevation of blood levels of zinc protoporphyrin by radiomimetic drugs and Friend leukemia virus.
Topics: Animals; Antineoplastic Agents; Bone Marrow Transplantation; Cyclophosphamide; Cytarabine; Erythropoiesis; Folic Acid Deficiency; Friend murine leukemia virus; Hydroxyurea; Leukemia, Experimental; Male; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Porphyrins; Protoporphyrins; Radiation Dosage; Radiation Effects; Whole-Body Irradiation | 1987 |
Effect of cycloheximide on development of methotrexate resistance of Chinese hamster ovary cells treated with inhibitors of DNA synthesis.
Topics: Animals; Cell Cycle; Cell Line; Cell Survival; Chromosome Aberrations; Cricetinae; Cycloheximide; DNA Replication; Drug Resistance; Female; Hydroxyurea; Methotrexate; Ovary | 1988 |
Enhancement by hemin of the sensitivity of K562 human leukemic cells to 1-beta-D-arabinofuranosylcytosine.
Topics: Aminolevulinic Acid; Butyrates; Cell Differentiation; Cell Line; Cytarabine; Daunorubicin; Deoxyguanosine; Doxorubicin; Drug Synergism; Erythropoiesis; Heme; Hemin; Humans; Hydroxyurea; Leukemia, Myeloid; Methotrexate; Thymidine; Vincristine | 1986 |
A cytotoxic DNA precursor is taken up selectively by human cancer xenografts.
Topics: Animals; Choriocarcinoma; Colon; DNA; Female; Fluorouracil; Humans; Hydroxyurea; Idoxuridine; Methotrexate; Mice; Mice, Nude; Neoplasm Transplantation; Nucleic Acid Precursors; Pregnancy; Uterine Neoplasms | 1987 |
Chemosensitivity of human head and neck cancer xenografts in the clonogenic assay and in nude mice.
Topics: Animals; Cisplatin; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; In Vitro Techniques; Methotrexate; Mice; Mice, Nude; Neoplasm Transplantation; Rats; Tumor Stem Cell Assay | 1986 |
Chromosomal changes without DNA overproduction in hydroxyurea-treated mammalian cells: implications for gene amplification.
Topics: Animals; Cell Cycle; Cell Line; Cell Survival; Chromosome Aberrations; Chromosomes; Colchicine; Cricetinae; Cricetulus; DNA Replication; Gene Amplification; Hydroxyurea; Methotrexate | 1986 |
Cross-sensitivity of methylating agents, hydroxyurea, and methotrexate in human tumor cells of the Mer- phenotype.
Topics: Adenoviridae; Alkylating Agents; Cell Line; Cell Survival; Dacarbazine; Drug Resistance; Humans; Hydroxyurea; Methotrexate; Methyltransferases; Neoplasms; O(6)-Methylguanine-DNA Methyltransferase; Phenotype; Virus Replication | 1986 |
Hypercalcaemia in the accelerated phase of chronic myelogenous leukaemia: no relationship to the phenotype of the blast cells.
Topics: Adult; Bone Marrow Examination; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Hydroxyurea; Hypercalcemia; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Phenotype; Primary Myelofibrosis | 1985 |
Evidence for the involvement of substrate cycles in the regulation of deoxyribonucleoside triphosphate pools in 3T6 cells.
Topics: Animals; Aphidicolin; Cells, Cultured; Cytidine; Cytidine Diphosphate; Deoxyribonucleotides; Diterpenes; DNA Polymerase II; DNA Replication; Hydroxyurea; Kinetics; Methotrexate; Mice; Radioisotope Dilution Technique; Thymidine; Tritium | 1985 |
A cytogenetic investigation of DNA rereplication after hydroxyurea treatment: implications for gene amplification.
Topics: Animals; Bromodeoxyuridine; Cell Line; Cricetinae; Cricetulus; DNA Replication; Drug Resistance; Female; Gene Amplification; Hydroxyurea; Karyotyping; Metaphase; Methotrexate; Ovary | 1986 |
Fifth Gordon Hamilton-Fairley memorial lecture. Methotrexate resistance and gene amplification: an experimental model for the generation of cellular heterogeneity.
Topics: Animals; Cells, Cultured; Chromosome Aberrations; DNA; DNA Replication; Drug Resistance; Gene Amplification; Humans; Hydroxyurea; Methotrexate; Mice; Neoplasms; Tetrahydrofolate Dehydrogenase | 1985 |
Clonogenic response of cells of murine intestinal crypts to 12 cytotoxic drugs.
Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Survival; Clone Cells; Dose-Response Relationship, Drug; Fluorouracil; Hydroxyurea; Intestinal Mucosa; Male; Methotrexate; Mice; Mice, Inbred Strains; Vincristine | 1985 |
Increased gene amplification in L5178Y mouse lymphoma cells with hydroxyurea-induced chromosomal aberrations.
Topics: Animals; Cell Survival; Cells, Cultured; Chromosome Aberrations; DNA; DNA Replication; Drug Resistance; Flow Cytometry; Gene Amplification; Hydroxyurea; Lymphoma; Methotrexate; Mice; Sister Chromatid Exchange; Tetrahydrofolate Dehydrogenase | 1985 |
Erythropoietin-induced congenital erythrocytosis: treatment with myelosuppressive agents and hookworm infestation.
Topics: Bloodletting; Erythropoietin; Female; Hookworm Infections; Humans; Hydroxyurea; Infant; Methotrexate; Polycythemia | 1985 |
Chemotherapy in head and neck cancer.
Topics: Administration, Oral; Antineoplastic Agents; Arteries; Carcinoma, Squamous Cell; Head; Head and Neck Neoplasms; Humans; Hydroxyurea; Infusions, Parenteral; Injections, Intravenous; Methotrexate; Neoplasm Metastasis; Neoplasms; Palliative Care; Remission, Spontaneous; Time Factors | 1971 |
Chemotherapy of vesical and prostatic tumours.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Cobalt Isotopes; Cystitis; Daunorubicin; Ethoglucid; Fluorouracil; Humans; Hydroxyurea; Male; Methotrexate; Mitomycins; Nitrogen Mustard Compounds; Papilloma; Prostatic Neoplasms; Thiotepa; Urinary Bladder Neoplasms | 1971 |
The role of chemotherapy in the treatment of carcinoma of the oral cavity.
Topics: Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Carotid Arteries; Catheterization; Humans; Hydroxyurea; Infusions, Parenteral; Methods; Methotrexate; Mouth Neoplasms | 1972 |
Chemotherapy of cancer of the head and neck.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Catheterization; Cyclophosphamide; Glutamates; Head and Neck Neoplasms; Humans; Hydroxyurea; Infusions, Parenteral; Injections, Intravenous; Leucovorin; Methotrexate; Mouth Neoplasms; Pteridines; Remission, Spontaneous | 1973 |
Effects of X-rays and cytotoxic agents on the cell population of the crypts of the small intestine in mice. Cell proliferation kinetics after single administrations and effects of variations in multiple dose schedules.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Cell Count; Cyclophosphamide; Female; Hydroxyurea; Intestinal Mucosa; Intestine, Small; Male; Mechlorethamine; Methotrexate; Mice; Mitosis; Radiation Genetics; Time Factors | 1973 |
The effects of antibiotics and cancer chemotherapeutic agents on the cellular transport and antitumor activity of methotrexate in L1210 murine leukemia.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Biological Transport; Bleomycin; Cells, Cultured; Cephalothin; Dose-Response Relationship, Drug; Drug Synergism; Female; Glucocorticoids; Hydroxyurea; Kanamycin; Leukemia L1210; Methotrexate; Mice; Penicillins; Vinblastine; Vinca Alkaloids; Vincristine | 1973 |
Chemotherapy of lung cancer: the experience of the National Cancer Institute of Milan.
Topics: Adenocarcinoma; Bleomycin; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Doxorubicin; Fluorouracil; Humans; Hydroxyurea; Italy; Lung Neoplasms; Methotrexate; Procarbazine; Remission, Spontaneous | 1973 |
Chemotherapy in recurrent heat and neck cancer.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Hydroxyurea; Injections, Intra-Arterial; Injections, Intramuscular; Methotrexate; Neoplasm Recurrence, Local; Neoplasms; Vinblastine; Vincristine | 1974 |
Effect of cytostatic agents on the adhesion of human amniotic ell lines.
Topics: Amnion; Antineoplastic Agents; Cell Adhesion; Cell Line; Cells, Cultured; Chromium Radioisotopes; Daunorubicin; Erythritol; Ethylamines; Humans; Hydrogen-Ion Concentration; Hydroxyurea; In Vitro Techniques; Mannomustine; Mesylates; Methotrexate; Mitolactol; Staining and Labeling; Surface-Active Agents; Vinblastine | 1973 |
[Palliative chemotherapy of bronchial cancers. Current status of the problem].
Topics: Antineoplastic Agents; Bleomycin; Bronchial Neoplasms; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Therapy, Combination; Emetine; Fluorouracil; Humans; Hydroxyurea; Methotrexate; Mitomycins; Mustard Compounds; Palliative Care; Procarbazine; Thiotepa; Vinblastine | 1973 |
Cutaneous uses of the antiproliferative drugs.
Topics: Administration, Topical; Antimetabolites; Azauridine; Bleomycin; Chemical and Drug Induced Liver Injury; Enzyme Inhibitors; Humans; Hydroxyurea; Immunotherapy; Melanoma; Methotrexate; Mitosis; Mycosis Fungoides; Organ Specificity; Psoriasis; Skin Neoplasms | 1974 |
Combined chemotherapy, radiotherapy, and surgery in the treatment of advanced but localized solid malignant tumours.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cystadenocarcinoma; Drug Therapy, Combination; Esophageal Neoplasms; Female; Head and Neck Neoplasms; Humans; Hydroxyurea; Infusions, Parenteral; Injections, Intravenous; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasm Metastasis; Neoplasm Recurrence, Local; Skin Neoplasms; Tongue Neoplasms; Vincristine | 1974 |
Chemotherapy of induced skin tumors in mice.
Topics: Alkylating Agents; Animals; Antimetabolites; Antineoplastic Agents; Benz(a)Anthracenes; Busulfan; Carcinoma, Squamous Cell; Chlorambucil; Cortisone; Cyclophosphamide; Dactinomycin; Estradiol; Female; Fluorouracil; Hydroxyurea; Mercaptopurine; Methotrexate; Mice; Mitomycins; Neoplasms, Experimental; Nitrogen Mustard Compounds; Nitroso Compounds; Papilloma; Skin Neoplasms; Testosterone; Triethylenemelamine | 1968 |
Malignant hepatoma in the Bantu.
Topics: Adenoma, Bile Duct; Africa, Eastern; Alanine Transaminase; Antineoplastic Agents; Aspartate Aminotransferases; Black People; Blood Proteins; Carcinoma, Hepatocellular; Clinical Enzyme Tests; Cyclophosphamide; Cytarabine; Dactinomycin; Fluorouracil; gamma-Globulins; Humans; Hydroxyurea; Liver Neoplasms; Male; Mercaptopurine; Methotrexate; Mitomycins; Nitrogen Mustard Compounds; Prednisone; Prognosis; South Africa; Vincristine | 1970 |
[Limitations and risks of therapy of psoriasis with amethopterin and hydroxyurea].
Topics: Adult; Aged; Blood Coagulation Disorders; Chemical and Drug Induced Liver Injury; Chromosome Aberrations; Chromosome Disorders; Drug Eruptions; Female; Gastrointestinal Diseases; Hematopoietic System; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Psoriasis; Pyelonephritis | 1971 |
Chemotherapy for metastatic teratomas of the testis.
Topics: Adult; Antineoplastic Agents; Dactinomycin; Dysgerminoma; Follow-Up Studies; Humans; Hydroxyurea; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Nitrofurazone; Plicamycin; Remission, Spontaneous; Teratoma; Testicular Neoplasms; Vinblastine | 1972 |
Comparison of the effects of several inhibitors of the synthesis of nucleic acids upon the viability and progression through the cell cycle of cultured H. Ep. no. 2 cells.
Topics: Antimetabolites; Azaguanine; Carcinoma; Cell Division; Cell Line; Cell Survival; Cytarabine; DNA Replication; Dose-Response Relationship, Drug; Floxuridine; Fluorouracil; Humans; Hydroxyurea; Laryngeal Neoplasms; Mercaptopurine; Methotrexate; Mitosis; Ribonucleosides; Thioguanine; Time Factors; Tritium | 1972 |
Metabolic and ultrastructural studies in a patient with pustular psoriasis (von Zumbusch).
Topics: Adrenal Cortex Hormones; Blood Protein Disorders; Capillaries; Colchicine; Epithelial Cells; Estrogens, Conjugated (USP); Female; Humans; Hydroxyurea; Hypocalcemia; Iodoquinol; Leukocytes; Methotrexate; Microcirculation; Microscopy, Electron; Middle Aged; Psoriasis; Serum Albumin; Skin; Tetracycline | 1972 |
Cell kinetic studies in patients with small cell carcinoma of the lung.
Topics: Autoradiography; Biopsy; Bone Marrow; Carcinoma, Small Cell; Cell Division; Cyclohexanes; Cyclophosphamide; DNA Replication; Humans; Hydroxyurea; Lung Neoplasms; Lymph Nodes; Methotrexate; Nitrosourea Compounds; Remission, Spontaneous; Thymidine; Time Factors; Tritium | 1974 |
Effects of methotrexate and hydroxyurea on psoriatic epidermis. Preferential cytotoxic effects on psoriatic epidermis.
Topics: Administration, Oral; Administration, Topical; Biopsy; Dose-Response Relationship, Drug; Humans; Hydroxyurea; Methotrexate; Prednisone; Psoriasis; Skin; Triamcinolone Acetonide | 1974 |
Synergism of ICRF 159 and radiotherapy in treatment of experimental tumors.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Evaluation Studies as Topic; Fluorouracil; Hydroxyurea; Male; Methotrexate; Mice; Piperazines; Propane; Radiotherapy Dosage; Sarcoma, Experimental | 1974 |
Intracerebral Burkitt's lymphoma: pathology, clinical features and treatment.
Topics: Adolescent; Allopurinol; Brain Neoplasms; Burkitt Lymphoma; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Female; Humans; Hydroxyurea; Male; Methotrexate; Neoplasm Metastasis; Papilledema; Prednisolone; Vincristine | 1974 |
Selective toxicity of rifamycin derivatives for leukaemic human leucocytes.
Topics: Antibiotics, Antineoplastic; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Cell Differentiation; Cells, Cultured; DNA Nucleotidyltransferases; DNA, Neoplasm; Humans; Hydroxyurea; Kinetics; Leukemia; Leukocytes; Lymphocytes; Mercaptopurine; Methotrexate; Rifampin; RNA, Neoplasm; Thymidine; Tritium; Uridine | 1972 |
Optimism in leukemia treatment.
Topics: Acute Disease; Adult; Child; Cyclophosphamide; Cytarabine; Humans; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisolone; Thioguanine; Vincristine | 1973 |
In-vitro sensitivity to cytostatics in chronic myeloid leukaemia.
Topics: Antibiotics, Antineoplastic; Busulfan; Cells, Cultured; Cytotoxicity Tests, Immunologic; Daunorubicin; Drug Hypersensitivity; Humans; Hydroxyurea; Leukemia, Myeloid; Leukocytes; Mannitol; Mannomustine; Methotrexate | 1973 |
[Therapy of acute leukemias].
Topics: Adrenal Cortex Hormones; Asparaginase; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Humans; Hydroxyurea; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Thioguanine; Vincristine | 1973 |
Intensive chemotherapy in children with acute lymphoblastic leukemia (L-2 protocol).
Topics: Administration, Oral; Adolescent; Age Factors; Antineoplastic Agents; Asparaginase; Carmustine; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Follow-Up Studies; Humans; Hydroxyurea; Infant; Infections; Injections, Intravenous; Leukemia, Lymphoid; Male; Meningitis; Methotrexate; Prednisone; Remission, Spontaneous; Thioguanine; Vincristine | 1974 |
Comparative results obtained in the treatment of acute leukemia.
Topics: Antineoplastic Agents; Asparaginase; Carmustine; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Meningitis; Methotrexate; Prednisone; Thioguanine; Vincristine | 1973 |
Cancer chemotherapy: mechanisms of action.
Topics: Alkaloids; Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Binding Sites; Cytarabine; Drug Synergism; Enzyme Therapy; Folic Acid Antagonists; Humans; Hydroxyurea; Leucovorin; Mechlorethamine; Mercaptopurine; Methotrexate; Mitomycins; Neoplasms; Nucleic Acids; Purines; Pyrimidines; Steroids; Thioguanine; Vinblastine; Vincristine | 1973 |
[Proceedings: Immunosuppression and treatment of psoriasis using cytostatic agents].
Topics: Aged; Antineoplastic Agents; Azathioprine; Bibliographies as Topic; Chemical and Drug Induced Liver Injury; Humans; Hydroxyurea; Immunosuppression Therapy; Male; Methotrexate; Psoriasis | 1973 |
Pharmacology of 3,5-diamino-1,24-triazole (guanazole). 1. Antitumor activity of guanazole.
Topics: Amines; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Cyclophosphamide; Cytarabine; Depression, Chemical; Female; Hydroxyurea; In Vitro Techniques; Leukemia L1210; Leukemia, Experimental; Lymphoma, Large B-Cell, Diffuse; Male; Mast-Cell Sarcoma; Methotrexate; Mice; Neoplasms, Experimental; Nitrosourea Compounds; Plasmacytoma; Structure-Activity Relationship; Triazoles | 1972 |
Long-term effects of hydroxyurea in psoriases.
Topics: Adult; Aged; Biopsy; Erythrocytes, Abnormal; Female; Hemoglobinometry; Humans; Hydroxyurea; Leukocyte Count; Liver; Liver Cirrhosis; Liver Function Tests; Male; Methotrexate; Middle Aged; Psoriasis; Time Factors | 1972 |
Combined methotrexate and hydroxyurea therapy for psoriasis.
Topics: Administration, Oral; Adult; Arthritis; Drug Hypersensitivity; Female; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Psoriasis | 1973 |
Generalized pustular psoriasis.
Topics: Adrenal Cortex Hormones; Humans; Hydroxyurea; Methotrexate; Psoriasis | 1973 |
DNA replication and the nuclear membrane.
Topics: Animals; Autoradiography; Cell Count; Cell Division; Cell Membrane; Cell Nucleus; Cells, Cultured; Cricetinae; DNA; DNA Replication; Female; Fibroblasts; Hydroxyurea; Isotope Labeling; Methotrexate; Microscopy, Electron; Mitosis; Rodentia; Thymidine; Time Factors; Tritium | 1973 |
Chemotherapy of a spontaneous mammary carcinoma in mice: relation between in vitro-in vivo activity and blood and tumor concentrations of serveral antitumor drugs.
Topics: Animals; Antineoplastic Agents; Cells, Cultured; Daunorubicin; Epithelial Cells; Epithelium; Female; Hydroxyurea; In Vitro Techniques; Mammary Neoplasms, Experimental; Mercaptopurine; Methotrexate; Mice; Spectrometry, Fluorescence; Time Factors | 1973 |
The effects of chemotherapy on the morphology of solid tumours.
Topics: Antineoplastic Agents; Cell Division; Cell Nucleus; Cells; Cytarabine; Hydroxyurea; Intestinal Mucosa; Intestine, Small; Methotrexate; Microscopy, Electron; Mitosis; Neoplasms; Phagocytosis; Time Factors; Vinca Alkaloids | 1974 |
Delayed response to erythropoietin in polycythaemic animals treated with cytotoxic agents.
Topics: Animals; Blood Transfusion; Busulfan; Cell Differentiation; Cyclophosphamide; Erythrocytes; Erythropoiesis; Erythropoietin; Female; Hydroxyurea; Injections, Intramuscular; Injections, Intraperitoneal; Injections, Intravenous; Iron Radioisotopes; Iron-Dextran Complex; Methotrexate; Radiation Effects; Rats; Time Factors | 1974 |
Quick-response capacity in mice recently immunized to sheep erythrocytes: dependence on a transient cell population.
Topics: Animals; Antibody Formation; Antibody-Producing Cells; Cell Division; Erythrocytes; Female; Guinea Pigs; Hemolytic Plaque Technique; Hydroxyurea; Immune Sera; Immunization; Immunization, Secondary; Injections, Intraperitoneal; Leucovorin; Male; Methotrexate; Mice; Sheep; Spleen; Time Factors | 1971 |
Systemic chemotherapy for carcinoma of the cervix.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Cyclophosphamide; Female; Fluorouracil; Humans; Hydroxyurea; Mechlorethamine; Melphalan; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Progestins; Thiotepa; Urea; Uterine Cervical Neoplasms | 1967 |
[Treatment of psoriasis with hydroxyurea].
Topics: Adult; Aged; Female; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Psoriasis | 1972 |
Use of mouse vaginal and rectal epithelium to screen antimitotic effects of systemically administered drugs.
Topics: Animals; Antineoplastic Agents; Cytarabine; Epithelial Cells; Epithelium; Female; Fluorouracil; Hydroxyurea; Mechlorethamine; Methotrexate; Mice; Mitosis; Podophyllin; Rectum; Vagina; Vinblastine | 1971 |
Drugs in the treatment of leukemia.
Topics: Asparaginase; Busulfan; Chlorambucil; Cyclophosphamide; Cytarabine; Humans; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Pipobroman; Prednisolone; Vincristine | 1968 |
Studies on the effects of hydroxyurea and other anticancer drugs upon pyrimidine metabolism.
Topics: Amidohydrolases; Animals; Antineoplastic Agents; Ascites; Carbon Isotopes; Cyclophosphamide; Cytarabine; Deoxyuridine; DNA; Fluorouracil; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Leukocytes; Methotrexate; Mice; Neoplasms, Experimental; Orotic Acid; Pyrimidines; Transferases; Triazines | 1969 |
The X-Y-Z scheme of immunocyte maturation. VII. Cell division and the establishment of short-term IgM memory.
Topics: Animals; Antigen-Antibody Reactions; Antigens; Cell Division; Erythrocytes; Female; Hemolysis; Hydroxyurea; Immune Tolerance; Immunoglobulin M; Injections, Intraperitoneal; Leucovorin; Male; Methods; Methotrexate; Mice; Spleen; Time Factors | 1969 |
Implications of biochemical, cytokinetic, pharmacologic, and toxicologic relationships in the design of optimal therapeutic schedules.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Disease Models, Animal; DNA, Neoplasm; Fluorouracil; Half-Life; Hydroxyurea; In Vitro Techniques; Kinetics; Leukemia L1210; Mercaptopurine; Methotrexate; Mice; Mitosis; Nitrosourea Compounds; Thiosemicarbazones | 1970 |
Intravaginal and intrarectal screening of antimitotic drugs for topical effectiveness.
Topics: Animals; Antineoplastic Agents; Colchicine; Cytarabine; Daunorubicin; Evaluation Studies as Topic; Female; Fluorouracil; Hydroxyurea; Intestinal Mucosa; Mechlorethamine; Methods; Methotrexate; Mice; Mitosis; Mucous Membrane; Nitrosourea Compounds; Podophyllin; Rectum; Vagina; Vinblastine; Vincristine | 1971 |
Studies on thymidine kinase, thymidylate kinase, and deoxycytidylate deaminase of Chang liver cells.
Topics: Aminohydrolases; Carbon Isotopes; Culture Techniques; Cytosine Nucleotides; Dactinomycin; DNA; Feedback; Growth; Humans; Hydroxyurea; Liver; Methotrexate; Mitomycins; Nucleosides; Nucleotides; Phosphotransferases; Puromycin; Thymidine; Thymidine Kinase; Time Factors | 1968 |
Effect of chemotherapeutic agents on chromosomes of patients with lung cancer.
Topics: Adult; Antineoplastic Agents; Carcinoma, Bronchogenic; Chromosome Aberrations; Chromosomes; Cyclophosphamide; Humans; Hydroxyurea; Lung Neoplasms; Methotrexate; Streptonigrin | 1969 |
Disseminated melanoma. Biologic behavior and treatment.
Topics: Antineoplastic Agents; Chlorambucil; Cyclophosphamide; Dactinomycin; Fluorouracil; Humans; Hydrazines; Hydroxyurea; Lymph Node Excision; Lymphatic Metastasis; Melanoma; Melphalan; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Perfusion; Vincristine | 1967 |
[Chemotherapy of advanced head and neck cancer with a combination of bleomycin, vincristine, methotrexate and hydroxyuree or cis-dichloro-diamino-platinium. Analysis of local and general parameters of prognosis (author's transl)].
Topics: Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Hydroxyurea; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Vincristine | 1980 |
Sequential combination chemotherapy of advanced head and neck carcinoma: re-evaluation of a highly effective regimen.
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Doxorubicin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Leucovorin; Male; Mercaptopurine; Methotrexate; Middle Aged; Vincristine | 1981 |
Combined chemotherapy of head and neck squamous cell carcinomas with methotrexate, bleomycin, and hydroxyurea.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Hydroxyurea; Methotrexate; Middle Aged | 1981 |
Chemotherapy with the modified Bagshawe protocol for poor prognosis metastatic trophoblastic disease.
Topics: Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Leucovorin; Methotrexate; Neoplasm Metastasis; Pregnancy; Prognosis; Trophoblastic Neoplasms; Uterine Neoplasms; Vincristine | 1982 |
Hydroxyurea fails to improve the results of MBD chemotherapy in cancer of the head and neck, but reduces toxicity.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Drug Evaluation; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Hydroxyurea; Leukopenia; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Thrombocytopenia | 1983 |
Control of epidermal cell proliferation in vitro.
Topics: Adenosine; Animals; Cell Movement; Cells, Cultured; Culture Media; Cyclic AMP; Epinephrine; Glycoproteins; Histamine; Hot Temperature; Hydroxyurea; Methotrexate; Mitosis; Prostaglandins; Skin; Swine; Tetradecanoylphorbol Acetate; Vitronectin | 1984 |
Inhibitors of DNA precursor metabolism in Dictyostelium discoideum.
Topics: Aminopterin; Antimetabolites; Dictyostelium; DNA; Floxuridine; Folic Acid; Hydroxyurea; Methotrexate; Time Factors; Trimethoprim | 1982 |
Antimitotic drugs that enhance neuronal survival in olfactory bulb cell cultures.
Topics: Animals; Bromodeoxyuridine; Cells, Cultured; Cytarabine; Depression, Chemical; Floxuridine; Hydroxyurea; Methotrexate; Mitosis; Olfactory Bulb; Potassium; Rats; Rats, Inbred Strains; Thymidine | 1983 |
DNA chain elongation rates in marrow cells from vitamin B12-deficient patients and methotrexate-treated mice.
Topics: Anemia, Megaloblastic; Animals; Bone Marrow; Chromatography; DNA; Durapatite; Female; Humans; Hydroxyapatites; Hydroxyurea; Lymphocyte Activation; Male; Methotrexate; Mice; Mice, Inbred BALB C; Vitamin B 12 Deficiency | 1982 |
Interferon and sodium butyrate inhibit the stimulation of poly(ADP-ribose) synthetase in mouse cells stimulated to divide.
Topics: Animals; Butyrates; Butyric Acid; Cell Cycle; Cells, Cultured; DNA Replication; Floxuridine; Humans; Hydroxyurea; Interferon Type I; Kinetics; Methotrexate; Mice; NAD+ Nucleosidase; Poly(ADP-ribose) Polymerases | 1983 |
Relationship between chromatin structure and replication in mouse L-cells.
Topics: Animals; Chromatin; Cycloheximide; Cytarabine; DNA Replication; Floxuridine; Hydroxyurea; Isoleucine; L Cells; Methotrexate; Mice; Mitomycin; Mitomycins; Protein Biosynthesis; Structure-Activity Relationship | 1980 |
Murine L5178Y cells resulting in altered drug sensitivities from fractionated radiation exposure in vitro.
Topics: Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Etoposide; Fluorouracil; Hydroxyurea; Leukemia L5178; Leukemia, Experimental; Methotrexate; Mice; Vincristine | 1984 |
Loss of unstably amplified dihydrofolate reductase genes from mouse cells is greatly accelerated by hydroxyurea.
Topics: Animals; Cell Division; Cells, Cultured; Drug Resistance; Gene Amplification; Genes; Hydroxyurea; Kinetics; Methotrexate; Mice; Tetrahydrofolate Dehydrogenase | 1983 |
[Possibility of an artefact in determining hematopoietic stem cell proliferation by CFUs suicide methods].
Topics: Animals; Cell Cycle; Colony-Forming Units Assay; Cytarabine; Female; Hydroxyurea; Methotrexate; Mice; Tritium | 1983 |
Inhibition of DNA synthesis does not influence the H1 histone synthesis in Tetrahymena pyriformis.
Topics: Animals; DNA Replication; Histones; Hydroxyurea; Kinetics; Methotrexate; Tetrahymena pyriformis; Uridine | 1982 |
Effects of methotrexate in vitro on epidermal cell proliferation.
Topics: Animals; Cell Division; Cell Movement; Cells, Cultured; Culture Media; Dose-Response Relationship, Drug; Fetal Blood; Hot Temperature; Hydroxyurea; Methotrexate; Mitotic Index; Skin; Swine; Thymidine; Time Factors | 1983 |
Transforming activities of methotrexate, hydroxyurea and 5-fluorouracil in different cell systems.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Dose-Response Relationship, Drug; Ectromelia virus; Fluorouracil; Hydroxyurea; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Inbred DBA | 1983 |
Enhancement of methotrexate resistance and dihydrofolate reductase gene amplification by treatment of mouse 3T6 cells with hydroxyurea.
Topics: Animals; Cell Line; DNA Replication; Drug Resistance; Gene Amplification; Hydroxyurea; Methotrexate; Mice; Tetrahydrofolate Dehydrogenase | 1983 |
The effect of methotrexate and hydroxyurea on neutrophil chemotaxis.
Topics: Cell Movement; Chemotaxis, Leukocyte; Humans; Hydroxyurea; Leucovorin; Methotrexate; Neutrophils | 1980 |
Acute nonlymphoblastic leukemia: prognostic factors in adults with long-term follow-up.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bacterial Vaccines; Carmustine; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydroxyurea; Leukemia; Male; Methotrexate; Middle Aged; Platelet Count; Prognosis; Pseudomonas; Statistics as Topic; Thioguanine; Vincristine | 1982 |
Formation of UV-induced apoptosis relates to the cell cycle.
Topics: Animals; Cell Count; Cell Cycle; Cell Division; Cell Survival; Colchicine; Fluorouracil; Guinea Pigs; Hydroxyurea; Methotrexate; Skin; Sunburn; Ultraviolet Rays | 1982 |
[Persistent psoriasis: failure of PUVA and peritoneal dialysis-response to methotrexate and hydroxyurea].
Topics: Aged; Female; Humans; Hydroxyurea; Methotrexate; Peritoneal Dialysis; Photochemotherapy; Psoriasis; PUVA Therapy | 1982 |
Chemotherapy of hormone-resistant stage D prostatic cancer.
Topics: Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Estramustine; Fluorouracil; Humans; Hydroxyurea; Lomustine; Male; Melphalan; Methotrexate; Prednimustine; Prostatic Neoplasms | 1980 |
Comparative ultrastructural alterations in rabbit limb-buds after a teratogenic dose of either hydroxyurea or methotrexate.
Topics: Animals; Female; Germ Layers; Hydroxyurea; Methotrexate; Microscopy, Electron; Pregnancy; Rabbits; Teratogens; Time Factors | 1981 |
Synchronization of L1210 leukemia with hydroxyurea infusion and the effect of subsequent pulse dose chemotherapy.
Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Line; Cytarabine; Doxorubicin; Drug Evaluation, Preclinical; Drug Therapy, Combination; Hydroxyurea; Interphase; Leukemia L1210; Male; Methotrexate; Mice; Neoplasm Transplantation; Time Factors; Transplantation, Homologous | 1980 |
Conversion of partially single-stranded replicating DNA to double-stranded DNA is delayed in megaloblastic anaemia.
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Chromatography, Affinity; DNA Replication; DNA, Single-Stranded; Humans; Hydroxyurea; Kinetics; Lymphocytes; Methotrexate | 1980 |
Regulation of the ectopically expressed human glycoprotein alpha-subunit gene in the human hepatoma cell line NPLC.
Topics: Carcinoma, Hepatocellular; Cell Line; Colforsin; Dexamethasone; Gene Expression Regulation, Neoplastic; Glycoprotein Hormones, alpha Subunit; Humans; Hydroxyurea; Kinetics; Liver Neoplasms; Methotrexate; Protein Kinase C; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transcriptional Activation; Tumor Cells, Cultured | 1994 |
Fibroblast growth factor mediated alterations in drug resistance, and evidence of gene amplification.
Topics: Animals; Antineoplastic Agents; Aspartate Carbamoyltransferase; Aspartic Acid; Blotting, Southern; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Cell Line; Dihydroorotase; DNA; Drug Resistance; Fibroblast Growth Factor 2; Fibroblast Growth Factor 4; Fibroblast Growth Factors; Fibroblasts; Gene Amplification; Hydroxyurea; Methotrexate; Mice; Multienzyme Complexes; Phosphonoacetic Acid; Proto-Oncogene Proteins; Ribonucleotide Reductases; Suramin; Tetrahydrofolate Dehydrogenase; Transfection | 1994 |
Chemotherapy combined with surgery in the treatment of gestational trophoblastic disease (GTD).
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Choriocarcinoma; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Resistance; Etoposide; Female; Humans; Hydatidiform Mole; Hydroxyurea; Hysterectomy; Lung Neoplasms; Methotrexate; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Pregnancy; Salvage Therapy; Thoracotomy; Treatment Outcome; Trophoblastic Neoplasms; Uterine Hemorrhage; Uterine Neoplasms; Vincristine | 1993 |
PUVA and cancer: a case-control study.
Topics: Adult; Aged; Arsenic; Carcinoma, Squamous Cell; Case-Control Studies; Coal Tar; Combined Modality Therapy; Female; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; PUVA Therapy; Radiotherapy; Skin Neoplasms; Ultraviolet Therapy; X-Rays | 1993 |
The annual cost of psoriasis.
Topics: Adult; Cyclosporine; Etretinate; Female; Health Care Costs; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Phototherapy; Psoriasis; PUVA Therapy; Retrospective Studies; Ultraviolet Therapy | 1993 |
2',3'-Didehydro-3'-deoxythymidine: regulation of its metabolic activation by modulators of thymidine-5'-triphosphate biosynthesis.
Topics: Amides; Biotransformation; Biphenyl Compounds; Cell Line; Deoxyguanosine; Floxuridine; HIV; HIV Reverse Transcriptase; HIV-1; Humans; Hydroxyurea; Kinetics; Methotrexate; Models, Biological; Phosphorylation; Pyrazoles; Reverse Transcriptase Inhibitors; Ribonucleosides; Ribose; RNA-Directed DNA Polymerase; Stavudine; Thymidine Kinase; Thymine Nucleotides; Tumor Cells, Cultured | 1996 |
Effect of modulation of the transferrin receptor on gallium-67 uptake and cytotoxicity in lymphoma cell lines.
Topics: Antineoplastic Agents; Biological Transport; Cell Cycle; Cell Division; Cell Line; Cell Survival; Cytarabine; Flow Cytometry; Gallium Radioisotopes; Gene Expression; Humans; Hydroxyurea; Lymphoma; Methotrexate; Receptors, Transferrin; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1996 |
Plasma endothelin in psoriasis: possible relations to therapy and toxicity.
Topics: Acitretin; Cyclosporine; Endothelins; Humans; Hydroxyurea; Keratolytic Agents; Methotrexate; Psoriasis; Ranitidine | 1996 |
Overexpression of a heterologous thymidine kinase delays apoptosis induced by factor deprivation and inhibitors of deoxynucleotide metabolism.
Topics: Animals; Apoptosis; B-Lymphocytes; Cell Line; Cell Survival; Culture Media, Conditioned; Deoxyribonucleotides; Floxuridine; Herpesvirus 1, Human; Hydroxyurea; Interleukin-3; Kinetics; Methotrexate; Mice; Nucleic Acid Synthesis Inhibitors; Recombinant Proteins; Thymidine Kinase; Transfection | 1997 |
Bcl-2 and Bcl-XL can differentially block chemotherapy-induced cell death.
Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-X Protein; Clone Cells; Drug Resistance, Neoplasm; Etoposide; Fluorouracil; Gamma Rays; Genes, bcl-2; Humans; Hydroxyurea; Methotrexate; Mice; Proto-Oncogene Proteins c-bcl-2; Recombinant Fusion Proteins; S Phase; Teniposide; Transfection; Vincristine | 1997 |
Ribonucleotide reductase R2 gene expression and changes in drug sensitivity and genome stability.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Antisense Elements (Genetics); Aspartic Acid; Drug Resistance, Neoplasm; Gene Amplification; Gene Expression Regulation, Enzymologic; Genes, p53; Genetic Vectors; Hydroxyurea; L Cells; Methotrexate; Mice; Phosphonoacetic Acid; Retroviridae; Ribonucleotide Reductases; Tumor Cells, Cultured; Tumor Stem Cell Assay; Tumor Suppressor Protein p53 | 1997 |
Salvage therapy for relapsed or refractory childhood acute lymphocytic leukemia by alternative administration a lymphoid- and myeloid-directed chemotherapeutic regimen consisting of dual modulation of ara-C, hydroxyurea, and etoposide.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Child; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dexamethasone; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Fever; Gastrointestinal Diseases; Humans; Hydrocortisone; Hydroxyurea; Leucovorin; Male; Methotrexate; Mitoxantrone; Pilot Projects; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Salvage Therapy; Treatment Outcome | 1997 |
Fewer chromosome aberrations and earlier apoptosis induced by DNA synthesis inhibitors, a topoisomerase II inhibitor or alkylating agents in human cells with normal compared with mutant p53.
Topics: Alkylating Agents; Antineoplastic Agents; Aphidicolin; Apoptosis; B-Lymphocytes; Cell Division; Cell Line; Chromosome Aberrations; Cytarabine; DNA Replication; Etoposide; Humans; Hydroxyurea; Methotrexate; Mutagenesis; Nucleic Acid Synthesis Inhibitors; Radiation, Ionizing; Topoisomerase II Inhibitors; Tumor Suppressor Protein p53 | 1998 |
Chemotherapy for gestational trophoblastic tumours hastens menopause by 3 years.
Topics: Adult; Antineoplastic Agents; Choriocarcinoma; Dactinomycin; Etoposide; Female; Follow-Up Studies; Humans; Hydroxyurea; Leucovorin; Menopause, Premature; Mercaptopurine; Methotrexate; Middle Aged; Pregnancy; Retrospective Studies; Risk Factors; Trophoblastic Neoplasms | 1998 |
Acute promyelocytic leukemia in a patient with idiopathic myelofibrosis.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Hydroxyurea; Idarubicin; Leukemia, Promyelocytic, Acute; Mercaptopurine; Methotrexate; Mitoxantrone; Primary Myelofibrosis; Remission Induction | 1999 |
Differential sensitivity of double minute chromosomes to hydroxyurea treatment in cultured methotrexate-resistant mouse cells.
Topics: Animals; Cell Survival; Chromosomes; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Electrophoresis, Gel, Pulsed-Field; Gene Dosage; Hydroxyurea; Methotrexate; Mice; Mutation; Nucleic Acid Synthesis Inhibitors; Tetrahydrofolate Dehydrogenase; Tumor Cells, Cultured | 1999 |
In vitro cytotoxic effects of fludarabine (2-F-ara-A) in combination with commonly used antileukemic agents by isobologram analysis.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Cell Survival; Cyclophosphamide; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Drug Screening Assays, Antitumor; Drug Synergism; Etoposide; Humans; Hydroxyurea; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Methotrexate; Neoplastic Stem Cells; Tumor Cells, Cultured; Vidarabine; Vidarabine Phosphate; Vincristine | 2000 |
The role of p53 in death of IL-3-dependent cells in response to cytotoxic drugs.
Topics: Animals; Antineoplastic Agents; Apoptosis; Bleomycin; Bone Marrow Cells; Cells, Cultured; Cisplatin; Colony-Forming Units Assay; DNA Damage; DNA Replication; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Floxuridine; Genes, p53; Hematopoietic Stem Cells; Hydroxyurea; Interleukin-3; Methotrexate; Mice; Mice, Inbred C57BL; Mice, Knockout; Radiation Tolerance; Tumor Suppressor Protein p53 | 2000 |
The intracellular activation of lamivudine (3TC) and determination of 2'-deoxycytidine-5'-triphosphate (dCTP) pools in the presence and absence of various drugs in HepG2 cells.
Topics: Anti-HIV Agents; Cell Survival; Cytidine Triphosphate; Deoxycytosine Nucleotides; Dideoxynucleotides; Drug Interactions; Humans; Hydroxyurea; Lamivudine; Methotrexate; Phosphorylation; Tumor Cells, Cultured; Vidarabine | 2000 |
In vitro cytotoxic effects of a tyrosine kinase inhibitor STI571 in combination with commonly used antileukemic agents.
Topics: Antineoplastic Agents; Apoptosis; Benzamides; Cytarabine; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Inhibitors; Fusion Proteins, bcr-abl; Harringtonines; Homoharringtonine; Humans; Hydroxyurea; Imatinib Mesylate; Interferon-alpha; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Methotrexate; Microbial Sensitivity Tests; Neoplasm Proteins; Neoplasms; Piperazines; Pyrimidines; Tumor Cells, Cultured; Vincristine | 2001 |
Reduction of telomerase activity in human liver cancer cells by a histone deacetylase inhibitor.
Topics: Antineoplastic Agents; Butyrates; Cell Cycle; Cell Differentiation; Cell Division; Colchicine; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Hydroxyurea; Liver Neoplasms; Methotrexate; RNA; RNA, Messenger; Telomerase; Tumor Cells, Cultured | 2001 |
Role of Bax in apoptosis of IL-3-dependent cells.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Bone Marrow Cells; Caspases; Cell Line; Cell Membrane; Cell Separation; Cisplatin; Colony-Forming Units Assay; Dimerization; Enzyme Activation; Enzyme Inhibitors; Floxuridine; Gene Expression; Gene Expression Regulation; Hydroxyurea; Interleukin-3; MAP Kinase Signaling System; Methotrexate; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Weight; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Signal Transduction | 2001 |
Multiple herpes simplex virus infections with various resistance patterns in a matched unrelated donor transplant recipient.
Topics: Acyclovir; Antineoplastic Agents, Alkylating; Antiviral Agents; Bone Marrow Transplantation; Cidofovir; Combined Modality Therapy; Cyclosporine; Cytarabine; Cytomegalovirus Infections; Cytosine; Drug Resistance, Viral; Fatal Outcome; Foscarnet; Graft vs Host Disease; Herpes Genitalis; Herpes Simplex; Humans; Hydroxyurea; Immunocompromised Host; Immunosuppressive Agents; Interferons; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Methotrexate; Middle Aged; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Transplantation Conditioning; Whole-Body Irradiation | 2001 |
Ribonucleotide reductase and thymidine phosphorylation: two potential targets of azodicarbonamide.
Topics: Animals; Antineoplastic Agents; Azo Compounds; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Drug Interactions; Hydroxyurea; Immunosuppressive Agents; Methotrexate; Phosphorylation; Ribonucleotide Reductases; Thymidine; Thymine Nucleotides; Tumor Cells, Cultured | 2002 |
Analysis of single nucleotide polymorphism C3435T of the multidrug resistance gene MDR1 in acute lymphoblastic leukemia.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Case-Control Studies; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Genes, MDR; Humans; Hydroxyurea; Male; Mercaptopurine; Methotrexate; Polymorphism, Single Nucleotide; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tumor Cells, Cultured; Vincristine | 2003 |
Antiproliferative efficacy of the third-generation bisphosphonate, zoledronic acid, combined with other anticancer drugs in leukemic cell lines.
Topics: Antineoplastic Agents; Benzamides; Cell Death; Cell Division; Cell Line, Tumor; Cytarabine; Daunorubicin; Diphosphonates; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Hydroxyurea; Imatinib Mesylate; Imidazoles; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Methotrexate; Piperazines; Pyrimidines; Vincristine; Zoledronic Acid | 2004 |
Preoperative sequential chemotherapy in locally advanced squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cohort Studies; Disease-Free Survival; Feasibility Studies; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Remission Induction | 2005 |
Results of three polychemotherapy programs in non-Hodgkin's lymphomas.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Female; Humans; Hydroxyurea; Leucovorin; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Neoplasm Staging; Prednisone; Treatment Outcome; Vincristine | 1989 |
Adverse events from systemic therapies for psoriasis are common in clinical practice.
Topics: Adult; Aged; Biological Products; Cyclosporine; Dermatologic Agents; Female; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Psoriasis; PUVA Therapy; Retinoids; Retrospective Studies | 2006 |
Characteristics and outcome of connective tissue diseases in patients with sickle-cell disease: report of 30 cases.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Arthritis, Rheumatoid; Blood Transfusion; Drug Therapy, Combination; Female; France; Glucocorticoids; Humans; Hydroxyurea; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Male; Methotrexate; Retrospective Studies; Risk Assessment; Severity of Illness Index; Survival Rate; Treatment Outcome | 2008 |
Maternal and perinatal outcomes of first pregnancy after chemotherapy for gestational trophoblastic neoplasia in Brazilian women.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brazil; Cisplatin; Cohort Studies; Cyclophosphamide; Dactinomycin; Doxorubicin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Hydroxyurea; Methotrexate; Pregnancy; Pregnancy Outcome; Retrospective Studies; Risk Factors; Vincristine | 2009 |
DNA synthesis as a therapeutic target: the first 65 years.
Topics: Aminopterin; Antimetabolites, Antineoplastic; DNA Replication; Fluorouracil; Folic Acid; Folic Acid Antagonists; History, 20th Century; Humans; Hydroxyurea; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetrahydrofolate Dehydrogenase | 2012 |
Cyclophosphamide, hydroxyurea, actinomycin D, methotrexate, and vincristine in the treatment of gestational trophoblastic neoplasia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dactinomycin; Female; Gestational Trophoblastic Disease; Humans; Hydroxyurea; Methotrexate; Neoplasm Recurrence, Local; Neutropenia; Pregnancy; Retrospective Studies; Salvage Therapy; Stomatitis; Survival Rate; Treatment Outcome; Vincristine; Vomiting | 2015 |
Survival prognostic factors for metachronous second primary head and neck squamous cell carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Chemoradiotherapy; Cisplatin; Deoxycytidine; Docetaxel; Female; Fluorouracil; Gemcitabine; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Neoplasm Staging; Neoplasms, Second Primary; Paclitaxel; Prognosis; Squamous Cell Carcinoma of Head and Neck; Survival Analysis; Taxoids; Treatment Outcome; Young Adult | 2017 |
Characteristics and Management of Autoimmune Bullous Disease in Psoriasis Patients.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Aged, 80 and over; Autoimmune Diseases; Cyclosporine; Disease Management; Enzyme Inhibitors; Female; Glucocorticoids; Humans; Hydroxyurea; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Mycophenolic Acid; Pemphigoid, Bullous; Pemphigus; Psoriasis; Retrospective Studies; Ultraviolet Therapy | 2019 |
Angiokeratoma-like purpuric palmar nodules following chemotherapy.
Topics: Angiokeratoma; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Diagnosis, Differential; Female; Hand Dermatoses; Humans; Hydroxyurea; Leukemia; Methotrexate; Middle Aged; Purpura; Skin Neoplasms | 2021 |
Unraveling the Mechanisms of Clinical Drugs-Induced Neural Tube Defects Based on Network Pharmacology and Molecular Docking Analysis.
Topics: Animals; Anticonvulsants; Antineoplastic Agents; Class I Phosphatidylinositol 3-Kinases; ErbB Receptors; Female; Fluorouracil; Hydroxyurea; Methotrexate; Mice; Molecular Docking Simulation; Network Pharmacology; Neural Tube Defects; Phosphatidylinositol 3-Kinases; Pregnancy; Tretinoin; Valproic Acid | 2022 |
Pilot study to estimate the safety and effectiveness of hydroxyurea and methotrexate recurrent langerhans cell histiocytosis (LCH-HU-pilot).
Topics: Histiocytosis, Langerhans-Cell; Humans; Hydroxyurea; Methotrexate; Pilot Projects; Recurrence | 2022 |