hydroxyurea and mercaptopurine

hydroxyurea has been researched along with mercaptopurine in 83 studies

Research

Studies (83)

Timeframe	Studies, this research(%)	All Research%
pre-1990	54 (65.06)	18.7374
1990's	8 (9.64)	18.2507
2000's	10 (12.05)	29.6817
2010's	9 (10.84)	24.3611
2020's	2 (2.41)	2.80

Authors

Authors	Studies
Hansch, C; Khwaja, TA; Selassie, CD	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Calvert, AH; Hill, BT; Hughes, KB; Price, LA; Shaw, HJ	1
Borsos, T; Ohanian, SH; Segerling, M	1
Alberto, P; Cavalli, F; Martz, G; Tschopp, L	1
Fleischer, J	1
Brattain, MG; Coleman, MS; Crist, WM; Sarrif, A; Vinson, PC; Vogler, LB	1
Buckner, CD; Sanders, JE; Stewart, P; Thomas, ED	1
Brunner, KW; Carey, RW; Cuttner, J; DelDuca, V; Glidewell, OJ; Hoagland, HC; Holland, JF; Kung, FH; Silver, RT; Spurr, CL; Wiernik, PH	1
Broggini, M; Colombo, T; Donelli, MG; Garattini, S	1
el Ashkar, A; Pazdernik, TL; Uyeki, EM	1
Brincker, H	1
Burchenal, JH; D'Angio, G; Exelby, P; Lieberman, PH; Murphy, ML; Wollner, N	1
Kim, DN; Kwak, YS; Lee, KT	1
Hashimoto, S; Shibata, A	1
Clifford, P; Grant, HR	1
Brouns, MC; Fitchen, JH; Riscoe, MK	1
De Gaetano, G; Sonnino, A	1
Berger, M; Chamberlain, M; Choucair, A; Da Silva, V; Davis, RL; Levin, VA; Liu, HC; Murovic, J; Phuphanich, S; Seager, M	1
Edwards, MS; Fulton, D; Levin, V; Prados, M; Rodriguez, LA; Silver, P	1
Bernasconi, C; Brusamolino, E; Castelli, G; Inverardi, D; Lazzarino, M; Merante, S; Morra, E	1
Duhamel, G; Gorin, NC; Laporte, JP; Lemoine, F; Najman, A	1
Greenwald, ES	1
Dantzig, PI	1
Sugiura, K	1
Falkson, G; Geddes, EW	1
Adamson, DJ; Bowdon, BJ; Vail, MH; Wheeler, GP	1
Lea, MA; Morris, HP; Musella, A; Sasovetz, D	1
Gallo, RC; Levine, P; Smith, RG; Ting, RC; Whang-Peng, J	1
Huguley, CM	1
Jungi, WF	1
Alberto, P; Brunner, KW; Martz, G; Nagel, G; Obrecht, JP; Senn, HJ	1
Conroy, JF	1
Sokal, JE	1
Balconi, G; Bossi, A; Donelli, MG; Filippeschi, S; Franchi, G; Garattini, S; Morasca, L	1
Lüscher, EF	1
Benckhuijsen, C	1
Dano, K; Nissen, NI	1
von Kreybig, T	1
Johnson, RE; Wilson, JF	1
Schreiner, L; von Kreybig, T	1
Brockman, RW; Lloyd, HH; Mellett, LB; Montgomery, JA; Schabel, FM; Skipper, HE; Wilkoff, LJ	1
Kallio, T; Kukko, E	1
Glick, JH; Taylor, SG; Zehngebot, LM	1
Barzan, L; Comoretto, R; Galligioni, E; Grigoletto, E; Magri, MD; Tirelli, U; Trovò, MG; Tumolo, S; Veronesi, A	1
Fleischer, J; Franke, WG	1
Grätz, R; Kröger, H	1
Annino, L; Mandelli, F; Mariani, G; Solinas, S	1
Cavalli, F; Coleman, M; Glidewell, O; Holland, JF; Kostinas, JE; Pajak, TF; Rai, KR; Silver, RT	1
Berthier, R; Hollard, D; Leger, J; Michallet, M; Sotto, JJ	1
Krykowski, E; Mazurowa, A; Olszańska-Skorek, T; Polkowska-Kulesza, E; Płuzańska, A; Robak, T	1
McDonald, CJ	1
Fauci, AS; Flaum, MA; Gralnick, HR; Schooley, RT	2
Andrac, L; Angeli-Besson, C; Jacquet, P; Koeppel, MC; Sayag, J	1
Amabile, M; Arpinati, M; Farabegoli, P; Martinelli, G; Testoni, N; Tura, S; Visani, G; Zaccaria, A; Zinzani, PL; Zuffa, E	1
Behar, C; Bertrand, Y; Dhooge, C; Lutz, P; Machinaud-Lacroix, F; Marguerite, F; Mazingue, F; Otten, J; Philippe, N; Plouvier, E; Rialland, X; Rubie, C; Souillet, G; Vilmer, E; Zix-Kieffer, I	1
Bagshawe, KD; Bower, M; Foskett, M; Holden, L; Newlands, ES; Rustin, GJ; Short, D	1
Bocci, G; Danesi, R; Del Tacca, M; Di Paolo, A; Fogli, S; Innocenti, F	1
Batlle, M; Feliu, E; Fernández-Avilés, F; Gómez Espuch, J; Granada, I; Millá, F; Navarro, JT; Ribera, JM	1
Guo, Y; Li, J; Pan, J; Shen, Y; Wu, Y; Xue, Y	1
Armata, J; Balcerska, A; Bogusławska-Jaworska, J; Boruczkowski, D; Bubała, H; Chybicka, A; Cwiklińska, M; Hicke, A; Kaczmarek-Kanold, M; Kałwak, K; Kolecki, P; Kowalczyk, J; Krauze, A; Matysiak, M; Płoszyńska, A; Rokicka-Milewska, R; Sikorska-Fic, B; Sońta-Jakimczyk, D; Staszak-Kowalska, R; Tomaszewska, R; Turkiewicz, D; Wachowiak, J; Wiśniewska-Slusarz, H; Wysocki, M	1
Hochhaus, A; Lahaye, T; Müller, MC	1
Becker, CM; Chitambar, CR; Drexler, HG; Efferth, T; Gebhart, E; Humeny, A; Miyachi, H; Sauerbrey, A; Steinbach, D; Zintl, F	1
BEATTY, EC; BRUBAKER, C; HAMMOND, D; HARTMANN, JR; ORIGENES, ML; SHORE, N; WILLIAMS, KO	1
Hara, S; Ishitsuka, K; Iwao, Y; Shirahashi, A; Shishime, M; Suzumiya, J; Takamatsu, Y; Takatsuka, Y; Tamura, K; Utsunomiya, A	1
Chahoud, I; Paumgartten, FJ	1
Bruserud, Ø; Fredly, H; Gjertsen, BT; Stapnes Bjørnsen, C	1
Bruserud, Ø; Fredly, HK; Gjertsen, BT; Grønningsæter, IS; Hatfield, KJ	1
Charoenprasert, K; Chinthammitr, Y; Kasyanan, H; Panoi, N; Phinyo, P; Pongudom, S; Purattanamal, J; Surawong, A; Wongyai, K	1

Reviews

11 review(s) available for hydroxyurea and mercaptopurine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Purine metabolism as a target for leukemia chemotherapy. Blood reviews, 1989, Volume: 3, Issue:3 Topics: Antineoplastic Agents; Drugs, Investigational; Humans; Hydroxyurea; Leukemia; Mercaptopurine; Methotrexate; Pentostatin; Purines; Thioguanine	1989
Cancer chemotherapy. II. New York state journal of medicine, 1972, Nov-01, Volume: 72, Issue:21 Topics: Animals; Antineoplastic Agents; Asparaginase; Azathioprine; Bleomycin; Cytarabine; Dactinomycin; Daunorubicin; Dimethylamines; Doxorubicin; Floxuridine; Fluorouracil; Humans; Hydroxyurea; Imidazoles; Mercaptopurine; Mitomycins; Mitotane; Neoplasms; Nitrosourea Compounds; Pipobroman; Procarbazine; Streptonigrin; Streptozocin; Thioguanine; Triazenes; Triazines; Vinblastine; Vincristine	1972
Immunosuppressive and cytotoxic drugs in dermatology. Archives of dermatology, 1974, Volume: 110, Issue:3 Topics: Animals; Antineoplastic Agents; Azathioprine; Azauridine; Bleomycin; Chlorambucil; Cyclophosphamide; Cytarabine; Dactinomycin; Humans; Hydroxyurea; Immunosuppressive Agents; Mercaptopurine; Methotrexate; Procarbazine; Skin Diseases; Skin Neoplasms; Vinblastine; Vincristine	1974
Current concepts in the treatment of chronic myelocytic leukemia. Annual review of medicine, 1973, Volume: 24 Topics: Antineoplastic Agents; Blood Platelet Disorders; Bromine; Busulfan; Dose-Response Relationship, Drug; Galactitol; Humans; Hydroxyurea; Immunotherapy; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mannitol; Mercaptopurine; Splenectomy; Uracil Mustard	1973
[Biochemical aspects of the therapy of advanced malignant tumors]. Wiener klinische Wochenschrift, 1966, Jul-01, Volume: 78, Issue:26 Topics: Adrenal Cortex Hormones; Alkaloids; Androgens; Anti-Bacterial Agents; Cyclophosphamide; DNA; DNA, Neoplasm; Estrogens; Fluorouracil; Folic Acid Antagonists; Humans; Hydroxyurea; Mercaptopurine; Neoplasms; Nucleic Acids; Protein Biosynthesis; Ribosomes; RNA, Messenger; RNA, Neoplasm; Vinblastine	1966
Chemotherapy and the life cycle of leukaemic cells. A comparison between the growth characteristics of human acute leukaemia and the murine leukaemia L 1210. Folia medica Neerlandica, 1969, Dec-02, Volume: 12, Issue:2 Topics: Anilides; Animals; Cell Division; Cyclophosphamide; Cytarabine; DNA, Neoplasm; Fluorouracil; Humans; Hydroxyurea; In Vitro Techniques; Leukemia; Leukemia L1210; Leukemia, Lymphoid; Mechlorethamine; Mercaptopurine; Methotrexate; Mice; Mitosis; Nitroso Compounds; Prednisone; Thymidine; Time Factors; Tritium; Vinblastine; Vincristine	1969
[New principles of treatment in acute leukemia]. Ugeskrift for laeger, 1970, Apr-30, Volume: 132, Issue:18 Topics: Adolescent; Adult; Antineoplastic Agents; Central Nervous System Diseases; Child; Cyclophosphamide; Cytarabine; Female; Guanidines; Humans; Hydroxyurea; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukopenia; Male; Mercaptopurine; Methotrexate; Middle Aged; Nitroso Compounds; Prednisone; Thrombocytopenia; Urea; Uric Acid; Vincristine	1970
[Carcinogenesis and teratogenesis. Comparative studies from the viewpoint of teratology]. Arzneimittel-Forschung, 1970, Volume: 20, Issue:5 Topics: Abnormalities, Drug-Induced; Alkylating Agents; Animals; Antineoplastic Agents; Carcinogens; Cyclophosphamide; Embryo, Mammalian; Female; Fetus; Fluorouracil; Gestational Age; Hydroxamic Acids; Hydroxyurea; Mannomustine; Mechlorethamine; Mercaptopurine; Nitroso Compounds; Pregnancy; Rats; Urethane	1970
Chemotherapy for squamous cell carcinoma of the head and neck: a progress report. American journal of otolaryngology, 1980, Volume: 1, Issue:4 Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Mechlorethamine; Mercaptopurine; Methotrexate; Procarbazine; Vinblastine	1980
The uses of systemic chemotherapeutic agents in psoriasis. Pharmacology & therapeutics, 1981, Volume: 14, Issue:1 Topics: Administration, Topical; Anthralin; Azathioprine; Azauridine; Chemical Phenomena; Chemistry; Humans; Hydroxyurea; Mercaptopurine; Mustard Compounds; Mycophenolic Acid; Psoriasis	1981

Trials

5 trial(s) available for hydroxyurea and mercaptopurine

Article	Year
[Combination chemotherapy in acute blast crisis of chronic myeloid leukaemia (author's transl)]. Deutsche medizinische Wochenschrift (1946), 1977, Aug-12, Volume: 102, Issue:32 Topics: Adolescent; Adult; Aged; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisone; Prospective Studies; Remission, Spontaneous; Switzerland; Vincristine	1977
A comparative trial of daunorubicin, cytosine arabinoside, and thioguanine, and a combination of the three agents for the treatment of acute myelocytic leukemia. Medical and pediatric oncology, 1979, Volume: 6, Issue:3 Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Bone Marrow; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Remission, Spontaneous; Thioguanine	1979
Hydroxyurea and 6-mercaptopurine in the treatment of chronic granulocytic leukemia. American journal of clinical oncology, 1986, Volume: 9, Issue:1 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Female; Humans; Hydroxyurea; Leukemia, Myeloid; Leukocyte Count; Male; Mercaptopurine; Middle Aged	1986
Chemotherapy for squamous cell carcinoma of the head and neck: a progress report. American journal of otolaryngology, 1980, Volume: 1, Issue:4 Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Mechlorethamine; Mercaptopurine; Methotrexate; Procarbazine; Vinblastine	1980
Efficacy and Safety of Metronomic Chemotherapy Versus Palliative Hydroxyurea in Unfit Acute Myeloid Leukemia Patients: A Multicenter, Open-Label Randomized Controlled Trial. Asian Pacific journal of cancer prevention : APJCP, 2020, Jan-01, Volume: 21, Issue:1 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Etoposide; Female; Follow-Up Studies; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisolone; Prognosis; Survival Rate	2020

Other Studies

68 other study(ies) available for hydroxyurea and mercaptopurine

Article	Year
Structure-activity relationships of antineoplastic agents in multidrug resistance. Journal of medicinal chemistry, 1990, Volume: 33, Issue:7 Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured	1990
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
Kinetically-based multiple drug treatment for advanced head and neck cancer. British medical journal, 1975, Jul-05, Volume: 3, Issue:5974 Topics: Antineoplastic Agents; Bleomycin; Doxorubicin; Drug Synergism; Drug Therapy, Combination; Ear Neoplasms; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Hydroxyurea; Laryngeal Neoplasms; Maxillary Neoplasms; Mercaptopurine; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Neoplasms; Tongue Neoplasms; Tonsillar Neoplasms; Vincristine	1975
Enhancing effect by metabolic inhibitors on the killing of tumor cells by antibody and complement. Cancer research, 1975, Volume: 35, Issue:11 Pt 1 Topics: Animals; Antibodies, Neoplasm; Antigen-Antibody Reactions; Antineoplastic Agents; Azacitidine; Carcinoma, Hepatocellular; Cells, Cultured; Complement System Proteins; Cyclophosphamide; Cytarabine; Dactinomycin; Doxorubicin; Fluorouracil; Guinea Pigs; Hydroxyurea; Liver Neoplasms; Mercaptopurine; Methotrexate; Mitomycins; Neoplasms, Experimental; Puromycin; Vincristine	1975
[Splenectomy and polychemotherapy in chronic myelosis]. Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1979, Jun-15, Volume: 34, Issue:12 Topics: Busulfan; Cytarabine; Daunorubicin; Humans; Hydroxyurea; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Mitobronitol; Prognosis; Splenectomy; Vincristine	1979
Philadelphia-chromosome-positive pre-B-cell leukemia presenting as blast crisis of chronic myelogenous leukemia. Blood, 1979, Volume: 54, Issue:5 Topics: B-Lymphocytes; Cell Transformation, Neoplastic; Child; Chromosomes, Human, 21-22 and Y; Humans; Hydroxyurea; Leukemia; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Phenotype; Prednisone; Time Factors; Vincristine	1979
Successful treatment of juvenile chronic granulocytic leukemia with marrow transplantation. Pediatrics, 1979, Volume: 63, Issue:1 Topics: Bone Marrow Transplantation; Busulfan; Child, Preschool; Cyclophosphamide; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Transplantation, Homologous	1979
Differential distribution of antitumor agents in primary and secondary tumors. Cancer treatment reports, 1977, Volume: 61, Issue:7 Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Carcinoma 256, Walker; Cyclophosphamide; Daunorubicin; Doxorubicin; Female; Hydroxyurea; Lung Neoplasms; Lymphatic Metastasis; Male; Mercaptopurine; Methotrexate; Methylnitrosourea; Mice; Neoplasm Metastasis; Neoplasms, Experimental; Rats; Sarcoma, Experimental	1977
Toxicity of antitumor agents on hemopoietic colony forming cells. The Journal of pharmacology and experimental therapeutics, 1976, Volume: 198, Issue:1 Topics: Animals; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Cyclophosphamide; Cytarabine; Female; Femur; Hematopoietic Stem Cells; Hydroxyurea; Mercaptopurine; Methotrexate; Mice; Mice, Inbred Strains; Spleen	1976
Treatment of therapy-resistant acute myeloid leukaemia with 7 and 8 cytostatics. Scandinavian journal of haematology, 1975, Volume: 14, Issue:1 Topics: Adolescent; Adult; Aged; Candidiasis; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Resistance; Drug Therapy, Combination; Esophagitis, Peptic; Female; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Leukocyte Count; Leukopenia; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisolone; Stomach Ulcer; Thioguanine; Vincristine	1975
Non-Hodgkin's lymphoma in children. A comparative study of two modalities of therapy. Cancer, 1976, Volume: 37, Issue:1 Topics: Adolescent; Antineoplastic Agents; Asparaginase; Carmustine; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Lymphoma; Male; Mercaptopurine; Methotrexate; Neoplasm Metastasis; Prednisone; Thioguanine; Vinblastine; Vincristine	1976
Study of drugs affecting cholesterol-induced atherosclerosis in rabbits. Advances in experimental medicine and biology, 1976, Volume: 67, Issue:00 Topics: Animals; Arteriosclerosis; Aspirin; Chloroquine; Cholesterol, Dietary; Clomipramine; Hydroxyurea; Male; Mercaptopurine; Pharmacology; Pyridinolcarbamate; Rabbits; Sodium Dodecyl Sulfate	1976
[Therapy of chronic myelogenous leukemia]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1992, Jul-10, Volume: 81, Issue:7 Topics: Alkylating Agents; Animals; Bone Marrow Transplantation; Combined Modality Therapy; Humans; Hydroxyurea; Interferons; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mercaptopurine; Philadelphia Chromosome	1992
Postcricoid carcinoma: a retrospective study of 13 patients. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 1985, Volume: 11, Issue:1 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Doxorubicin; Female; Fluorouracil; Humans; Hydroxyurea; Laryngeal Neoplasms; Male; Mercaptopurine; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Retrospective Studies; Vincristine	1985
[Long-time treatment with full-dosage ranitidine in a case of myelodyserythropoiesis (blastic leukosis) treated with prednisone and antiblastic agents]. La Clinica terapeutica, 1988, Sep-30, Volume: 126, Issue:6 Topics: Aged; Anemia, Refractory, with Excess of Blasts; Drug Evaluation; Humans; Hydroxyurea; Male; Mercaptopurine; Prednisone; Ranitidine	1988
Phase II study of combined carmustine, 5-fluorouracil, hydroxyurea, and 6-mercaptopurine (BFHM) for the treatment of malignant gliomas. Cancer treatment reports, 1986, Volume: 70, Issue:11 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Drug Evaluation; Fluorouracil; Glioblastoma; Glioma; Humans; Hydroxyurea; Mercaptopurine; Middle Aged; Neurologic Examination; Statistics as Topic; Tomography, X-Ray Computed	1986
Treatment of recurrent brain stem gliomas and other central nervous system tumors with 5-fluorouracil, CCNU, hydroxyurea, and 6-mercaptopurine. Neurosurgery, 1988, Volume: 22, Issue:4 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Brain Stem; Child; Child, Preschool; Ependymoma; Female; Fluorouracil; Glioma; Humans; Hydroxyurea; Lomustine; Male; Mercaptopurine; Neoplasm Recurrence, Local; Spinal Cord Neoplasms	1988
Vindesine-prednisone in the treatment of blast crisis of chronic myeloid leukemia. Cancer treatment reports, 1985, Volume: 69, Issue:2 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Drug Administration Schedule; Female; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Mercaptopurine; Middle Aged; Prednisone; Time Factors; Vinblastine; Vindesine	1985
Chemotherapy of induced skin tumors in mice. Gan, 1968, Volume: 59, Issue:5 Topics: Alkylating Agents; Animals; Antimetabolites; Antineoplastic Agents; Benz(a)Anthracenes; Busulfan; Carcinoma, Squamous Cell; Chlorambucil; Cortisone; Cyclophosphamide; Dactinomycin; Estradiol; Female; Fluorouracil; Hydroxyurea; Mercaptopurine; Methotrexate; Mice; Mitomycins; Neoplasms, Experimental; Nitrogen Mustard Compounds; Nitroso Compounds; Papilloma; Skin Neoplasms; Testosterone; Triethylenemelamine	1968
Malignant hepatoma in the Bantu. Cancer, 1970, Volume: 25, Issue:6 Topics: Adenoma, Bile Duct; Africa, Eastern; Alanine Transaminase; Antineoplastic Agents; Aspartate Aminotransferases; Black People; Blood Proteins; Carcinoma, Hepatocellular; Clinical Enzyme Tests; Cyclophosphamide; Cytarabine; Dactinomycin; Fluorouracil; gamma-Globulins; Humans; Hydroxyurea; Liver Neoplasms; Male; Mercaptopurine; Methotrexate; Mitomycins; Nitrogen Mustard Compounds; Prednisone; Prognosis; South Africa; Vincristine	1970
Comparison of the effects of several inhibitors of the synthesis of nucleic acids upon the viability and progression through the cell cycle of cultured H. Ep. no. 2 cells. Cancer research, 1972, Volume: 32, Issue:12 Topics: Antimetabolites; Azaguanine; Carcinoma; Cell Division; Cell Line; Cell Survival; Cytarabine; DNA Replication; Dose-Response Relationship, Drug; Floxuridine; Fluorouracil; Humans; Hydroxyurea; Laryngeal Neoplasms; Mercaptopurine; Methotrexate; Mitosis; Ribonucleosides; Thioguanine; Time Factors; Tritium	1972
Effects of hydroxyurea and 6-mercaptopurine on growth and some aspects of carbohydrate metabolism in regenerating and neoplastic liver. Cancer research, 1970, Volume: 30, Issue:7 Topics: Animals; Body Weight; Carcinoma, Hepatocellular; DNA; DNA, Neoplasm; Glucokinase; Glucose; Hepatectomy; Hexokinase; Hydroxyurea; Liver Glycogen; Liver Neoplasms; Liver Regeneration; Male; Mercaptopurine; Neoplasms, Experimental; Organ Size; Phosphofructokinase-1; Rats; Thymidine; Time Factors; Tritium	1970
Selective toxicity of rifamycin derivatives for leukaemic human leucocytes. Nature: New biology, 1972, Apr-12, Volume: 236, Issue:67 Topics: Antibiotics, Antineoplastic; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Cell Differentiation; Cells, Cultured; DNA Nucleotidyltransferases; DNA, Neoplasm; Humans; Hydroxyurea; Kinetics; Leukemia; Leukocytes; Lymphocytes; Mercaptopurine; Methotrexate; Rifampin; RNA, Neoplasm; Thymidine; Tritium; Uridine	1972
Chronic myelocytic and chronic lymphocytic leukemia. Cancer, 1972, Volume: 30, Issue:6 Topics: Age Factors; Antilymphocyte Serum; Antineoplastic Agents; Blood Cell Count; Busulfan; Chlorambucil; Humans; Hydroxyurea; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Prednisone; Prognosis; Remission, Spontaneous	1972
Optimism in leukemia treatment. Canadian Medical Association journal, 1973, Apr-07, Volume: 108, Issue:7 Topics: Acute Disease; Adult; Child; Cyclophosphamide; Cytarabine; Humans; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisolone; Thioguanine; Vincristine	1973
[Therapy of acute leukemias]. Schweizerische medizinische Wochenschrift, 1973, Sep-22, Volume: 103, Issue:38 Topics: Adrenal Cortex Hormones; Asparaginase; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Humans; Hydroxyurea; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Thioguanine; Vincristine	1973
[Therapy of acute leukemia. Results of the Swiss study group for clinical cancer research (SAKK)]. Schweizerische medizinische Wochenschrift, 1974, Jan-26, Volume: 104, Issue:4 Topics: Age Factors; Bone Marrow Examination; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Mercaptopurine; Nitrosourea Compounds; Prednisone; Remission, Spontaneous; Thioguanine; Vincristine	1974
Cancer chemotherapy: mechanisms of action. Seminars in drug treatment, 1973,Summer, Volume: 3, Issue:1 Topics: Alkaloids; Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Binding Sites; Cytarabine; Drug Synergism; Enzyme Therapy; Folic Acid Antagonists; Humans; Hydroxyurea; Leucovorin; Mechlorethamine; Mercaptopurine; Methotrexate; Mitomycins; Neoplasms; Nucleic Acids; Purines; Pyrimidines; Steroids; Thioguanine; Vinblastine; Vincristine	1973
Chemotherapy of a spontaneous mammary carcinoma in mice: relation between in vitro-in vivo activity and blood and tumor concentrations of serveral antitumor drugs. Cancer chemotherapy reports, 1973, Volume: 57, Issue:2 Topics: Animals; Antineoplastic Agents; Cells, Cultured; Daunorubicin; Epithelial Cells; Epithelium; Female; Hydroxyurea; In Vitro Techniques; Mammary Neoplasms, Experimental; Mercaptopurine; Methotrexate; Mice; Spectrometry, Fluorescence; Time Factors	1973
Drugs in the treatment of leukemia. British medical journal, 1968, Nov-02, Volume: 4, Issue:5626 Topics: Asparaginase; Busulfan; Chlorambucil; Cyclophosphamide; Cytarabine; Humans; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Pipobroman; Prednisolone; Vincristine	1968
Splenic irradiation following chemotherapy in chronic myelogenous leukemia. Radiology, 1971, Volume: 101, Issue:3 Topics: Adolescent; Adult; Aged; Blood Cell Count; Blood Platelets; Bone Marrow Diseases; Busulfan; Child; Cobalt Isotopes; Female; Hemoglobins; Humans; Hydroxyurea; Leukemia, Myeloid; Leukocyte Count; Male; Mercaptopurine; Middle Aged; Radiotherapy; Remission, Spontaneous; Spleen; Time Factors	1971
[Effect of cytostatics on the facial development of rats]. Archiv fur klinische und experimentelle Ohren- Nasen- und Kehlkopfheilkunde, 1969, Dec-22, Volume: 194, Issue:2 Topics: Abnormalities, Drug-Induced; Abnormalities, Severe Teratoid; Animals; Antineoplastic Agents; Cyclophosphamide; Face; Female; Gestational Age; Hydroxamic Acids; Hydroxyurea; Jaw Abnormalities; Limbic System; Mercaptopurine; Nitroso Compounds; Nose; Pregnancy; Rats	1969
Implications of biochemical, cytokinetic, pharmacologic, and toxicologic relationships in the design of optimal therapeutic schedules. Cancer chemotherapy reports, 1970, Volume: 54, Issue:6 Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Disease Models, Animal; DNA, Neoplasm; Fluorouracil; Half-Life; Hydroxyurea; In Vitro Techniques; Kinetics; Leukemia L1210; Mercaptopurine; Methotrexate; Mice; Mitosis; Nitrosourea Compounds; Thiosemicarbazones	1970
Accumulation of pyrophosphate correlates with the increased level of nucleoside triphosphates in Escherichia coli. Biochemistry international, 1984, Volume: 8, Issue:1 Topics: Adenosine Triphosphate; Chromatography, High Pressure Liquid; Diphosphates; Escherichia coli; Fluorouracil; Hydroxyurea; Luminescent Measurements; Mercaptopurine; Mutation; Ribonucleotides; Species Specificity; Uracil	1984
Sequential combination chemotherapy of advanced head and neck carcinoma: re-evaluation of a highly effective regimen. Strahlentherapie, 1981, Volume: 157, Issue:4 Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Doxorubicin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Leucovorin; Male; Mercaptopurine; Methotrexate; Middle Aged; Vincristine	1981
[Diagnosis and therapy of chronic monocytic leukemia]. Folia haematologica (Leipzig, Germany : 1928), 1981, Volume: 108, Issue:2 Topics: Aged; Chromosome Aberrations; Colloids; Diagnosis, Differential; Female; Humans; Hydroxyurea; Indium; Leukemia, Myeloid; Male; Mercaptopurine; Monocytes; Phagocytosis; Podophyllotoxin	1981
[Effect of L-tryptophan, nicotinamide, L-methionine and 1-methylnicotinamide on the embryotoxic effect of various substances]. Arzneimittel-Forschung, 1983, Volume: 33, Issue:7 Topics: 6-Aminonicotinamide; Animals; Cyclophosphamide; Drug Interactions; Embryo, Mammalian; Female; Hydroxyurea; Mercaptopurine; Methionine; Mice; Niacinamide; Pregnancy; Tryptophan	1983
Characterization and treatment of the non-lymphoblastic crisis of chronic myelogenous leukemia. Tumori, 1983, Dec-31, Volume: 69, Issue:6 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Child; Female; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Mercaptopurine; Middle Aged; Neoplasm Staging; Prednisone; Time Factors	1983
Combination chemotherapy for terminal-phase chronic granulocytic leukemia: cancer and leukemia group B studies. Blood, 1980, Volume: 55, Issue:1 Topics: Daunorubicin; Dexamethasone; Drug Therapy, Combination; Gastrointestinal Diseases; Hemorrhage; Humans; Hydroxyurea; Infections; Leukemia, Myeloid; Mercaptopurine; Prednisone; Remission, Spontaneous; Terminal Care	1980
High rate of long-term survivals in AML treated by chemotherapy and androgenotherapy: a pilot study. Cancer, 1980, Apr-01, Volume: 45, Issue:7 Topics: Adolescent; Adult; Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisone; Stanozolol; Vincristine; Virilism	1980
[Results of complex treatment of adults with myeloblastic leukemia]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 1980, Aug-04, Volume: 35, Issue:31 Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisone; Vincristine	1980
A clinicopathologic correlation of the idiopathic hypereosinophilic syndrome. I. Hematologic manifestations. Blood, 1981, Volume: 58, Issue:5 Topics: Bone Marrow; Busulfan; Cyclophosphamide; Dose-Response Relationship, Drug; Eosinophilia; Eosinophils; Erythrocytes; Female; Humans; Hydroxyurea; Male; Mercaptopurine; Prednisone; Syndrome	1981
A clinicopathologic correlation of the idiopathic hypereosinophilic syndrome. II. Clinical manifestations. Blood, 1981, Volume: 58, Issue:5 Topics: Adolescent; Adult; Aged; Child; Cyclophosphamide; Eosinophilia; Heart Diseases; Humans; Hydroxyurea; Mercaptopurine; Middle Aged; Mortality; Prednisone; Splenomegaly; Syndrome	1981
Multiple squamous-cell carcinomas of the scalp and chronic myeloid leukemia. Dermatology (Basel, Switzerland), 1995, Volume: 191, Issue:4 Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma, Squamous Cell; Humans; Hydroxyurea; Immunocompromised Host; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Mercaptopurine; Neoplasms, Multiple Primary; Scalp; Skin Neoplasms; Sunlight	1995
FLANG (fludarabine + cytosine arabinoside + novantrone + G-CSF) induces partial remission in lymphoid blast transformation of Ph+chronic myelogenous leukaemia. Leukemia & lymphoma, 1996, Volume: 22, Issue:1-2 Topics: Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Bone Marrow; Bone Marrow Transplantation; Chromosome Aberrations; Combined Modality Therapy; Cytarabine; Disease Progression; Granulocyte Colony-Stimulating Factor; Humans; Hydroxyurea; Immunologic Factors; Interferon-alpha; Karyotyping; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Mercaptopurine; Middle Aged; Mitoxantrone; Remission Induction; Vidarabine	1996
Juvenile myelomonocytic leukemia: analyses of treatment results in the EORTC Children's Leukemia Cooperative Group (CLCG). Bone marrow transplantation, 1996, Volume: 18, Issue:6 Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Etoposide; Female; Follow-Up Studies; Humans; Hydroxyurea; Immunologic Factors; Infant; Interferons; Isotretinoin; Leukemia, Myelomonocytic, Acute; Life Tables; Male; Mercaptopurine; Remission Induction; Retrospective Studies; Splenectomy; Transplantation Conditioning; Treatment Outcome; Whole-Body Irradiation	1996
Chemotherapy for gestational trophoblastic tumours hastens menopause by 3 years. European journal of cancer (Oxford, England : 1990), 1998, Volume: 34, Issue:8 Topics: Adult; Antineoplastic Agents; Choriocarcinoma; Dactinomycin; Etoposide; Female; Follow-Up Studies; Humans; Hydroxyurea; Leucovorin; Menopause, Premature; Mercaptopurine; Methotrexate; Middle Aged; Pregnancy; Retrospective Studies; Risk Factors; Trophoblastic Neoplasms	1998
Metabolism of 6-mercaptopurine in the erythrocytes, liver, and kidney of rats during multiple-dose regimens. Cancer chemotherapy and pharmacology, 1999, Volume: 43, Issue:2 Topics: Animals; Antimetabolites; Antimetabolites, Antineoplastic; Area Under Curve; Biotransformation; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Erythrocytes; Female; Hydroxyurea; Kidney; Liver; Mercaptopurine; Rats; Rats, Wistar; Regression Analysis; Ribavirin	1999
Acute promyelocytic leukemia in a patient with idiopathic myelofibrosis. Leukemia, 1999, Volume: 13, Issue:3 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Hydroxyurea; Idarubicin; Leukemia, Promyelocytic, Acute; Mercaptopurine; Methotrexate; Mitoxantrone; Primary Myelofibrosis; Remission Induction	1999
Pentasomy 8q resulting from duplication of isochromosome 8q in chronic myelomonocytic leukemia. Leukemia & lymphoma, 2002, Volume: 43, Issue:1 Topics: Aneuploidy; Chromosomes, Human, Pair 8; Cytogenetic Analysis; Fatal Outcome; Gene Duplication; Humans; Hydroxyurea; Isochromosomes; Leukemia, Myelomonocytic, Chronic; Male; Mercaptopurine; Middle Aged	2002
[Results of treatment of children with chronic myelogenous leukaemia (CML) obtained by the Polish Paediatric Leukaemia/Lymphoma Study Group]. Medycyna wieku rozwojowego, 2000, Volume: 4, Issue:1 Suppl 2 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Combined Modality Therapy; Disease-Free Survival; Etoposide; Female; Humans; Hydroxyurea; Infant; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Mercaptopurine; Poland; Remission Induction; Retrospective Studies; Stem Cell Transplantation; Transplantation, Homologous; Treatment Outcome	2000
[Resistance to tumor specific therapy with imatinib by clonal selection of mutated cells]. Deutsche medizinische Wochenschrift (1946), 2002, Oct-18, Volume: 127, Issue:42 Topics: Amino Acid Substitution; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Clone Cells; Drug Resistance, Neoplasm; Female; Fusion Proteins, bcr-abl; Histidine; Humans; Hydroxyurea; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mercaptopurine; Middle Aged; Oncogene Proteins, Fusion; Piperazines; Point Mutation; Pyrimidines; Selection, Genetic; Tyrosine	2002
Analysis of single nucleotide polymorphism C3435T of the multidrug resistance gene MDR1 in acute lymphoblastic leukemia. International journal of oncology, 2003, Volume: 23, Issue:2 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Case-Control Studies; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Genes, MDR; Humans; Hydroxyurea; Male; Mercaptopurine; Methotrexate; Polymorphism, Single Nucleotide; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tumor Cells, Cultured; Vincristine	2003
TRIAL OF HYDROXYUREA (NSC-32065) IN CANCER IN CHILDREN. Cancer chemotherapy reports, 1964, Volume: 37 Topics: Antineoplastic Agents; Busulfan; Child; Cyclophosphamide; Dactinomycin; Humans; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mercaptopurine; Neoplasms; Neuroblastoma; Sarcoma; Urea	1964
Bone marrow necrosis in a patient with acute promyelocytic leukemia during re-induction therapy with arsenic trioxide. European journal of haematology, 2004, Volume: 72, Issue:4 Topics: Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Bone Marrow; Bone Marrow Diseases; Fever; Humans; Hydroxyurea; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Middle Aged; Necrosis; Oxides; Pancytopenia; Remission Induction	2004
Dose-response relationships of rat fetal skeleton variations: Relevance for risk assessment. Environmental research, 2009, Volume: 109, Issue:7 Topics: Animals; Antineoplastic Agents; Bone and Bones; Dose-Response Relationship, Drug; Female; Floxuridine; Hydroxyurea; Maternal Exposure; Mercaptopurine; Pregnancy; Rats; Rats, Wistar	2009
Combination of the histone deacetylase inhibitor valproic acid with oral hydroxyurea or 6-mercaptopurin can be safe and effective in patients with advanced acute myeloid leukaemia--a report of five cases. Hematology (Amsterdam, Netherlands), 2010, Volume: 15, Issue:5 Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Female; Histone Deacetylase Inhibitors; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Mercaptopurine; Middle Aged; Treatment Outcome; Valproic Acid	2010
Systemic Metabolomic Profiling of Acute Myeloid Leukemia Patients before and During Disease-Stabilizing Treatment Based on All-Trans Retinoic Acid, Valproic Acid, and Low-Dose Chemotherapy. Cells, 2019, 10-10, Volume: 8, Issue:10 Topics: Aged; Aged, 80 and over; Amino Acids; Cytarabine; Drug Therapy; Female; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Lipid Metabolism; Male; Mercaptopurine; Metabolomics; Middle Aged; Treatment Outcome; Tretinoin; Valproic Acid	2019