Compounds > hydroxyurea

hydroxyurea and kanamycin a

hydroxyurea has been researched along with kanamycin a in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19903 (30.00)18.7374
1990's0 (0.00)18.2507
2000's2 (20.00)29.6817
2010's5 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Burr, RG1
Frisby, SA; Oliverio, VT; Zager, RF1
Elizan, TS; Schwartz, J1
Collins, JJ; Dwyer, DJ; Hayete, B; Kohanski, MA; Lawrence, CA1

Reviews

1 review(s) available for hydroxyurea and kanamycin a

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

9 other study(ies) available for hydroxyurea and kanamycin a

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Inhibition of urease by miscellaneous ions and compounds. Implications for the therapy of infection-induced urolithiasis.
    Investigative urology, 1977, Volume: 15, Issue:2

    Topics: Bacterial Infections; Humans; Hydroxamic Acids; Hydroxyurea; In Vitro Techniques; Ions; Kanamycin; Sulfanilamides; Urease; Urinary Calculi

1977
The effects of antibiotics and cancer chemotherapeutic agents on the cellular transport and antitumor activity of methotrexate in L1210 murine leukemia.
    Cancer research, 1973, Volume: 33, Issue:7

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Biological Transport; Bleomycin; Cells, Cultured; Cephalothin; Dose-Response Relationship, Drug; Drug Synergism; Female; Glucocorticoids; Hydroxyurea; Kanamycin; Leukemia L1210; Methotrexate; Mice; Penicillins; Vinblastine; Vinca Alkaloids; Vincristine

1973
Further characterization of suckling mouse cataract agent (SMCA): a slow, persistent infection of the nervous system.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 141, Issue:2

    Topics: Animals; Arboviruses; Bromodeoxyuridine; Cataract; Chick Embryo; Dactinomycin; Filtration; Hot Temperature; Hydrogen-Ion Concentration; Hydroxyurea; Inclusion Bodies, Viral; Kanamycin; Lens, Crystalline; Mice; Micropore Filters; Microscopy, Electron; Nervous System Diseases; Organ Culture Techniques; Particle Size; Penicillin Resistance; Penicillins; Rabbits; Rifampin; Slow Virus Diseases; Streptomycin; Trypsin; Ultraviolet Rays; Virus Replication

1972
A common mechanism of cellular death induced by bactericidal antibiotics.
    Cell, 2007, Sep-07, Volume: 130, Issue:5

    Topics: 2,2'-Dipyridyl; Ampicillin; Anti-Bacterial Agents; Carbon-Sulfur Lyases; Cell Death; Citric Acid Cycle; Colony Count, Microbial; DNA Damage; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Ferrous Compounds; Free Radical Scavengers; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Hydrogen Peroxide; Hydroxyl Radical; Hydroxyurea; Iron Chelating Agents; Kanamycin; Membrane Proteins; Microbial Viability; Mutation; NAD; Norfloxacin; Oxidative Stress; Rec A Recombinases; Staphylococcus aureus; Time Factors

2007