hydroxyurea has been researched along with isoniazid in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (39.39) | 18.7374 |
| 1990's | 6 (18.18) | 18.2507 |
| 2000's | 5 (15.15) | 29.6817 |
| 2010's | 8 (24.24) | 24.3611 |
| 2020's | 1 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Gao, J; Richardson, DR | 1 |
| Antholine, WE; Chitambar, CR; Green, DA; Richardson, DR; Wong, SJ | 1 |
| Davis, LE; Sacks, PG | 2 |
| Bode, HR; Yaross, MS | 1 |
| Bode, HR; Flick, KM; Smith, GS | 1 |
| Fujisawa, T | 1 |
| Littefield, CL | 1 |
| Bode, HR; Koizumi, O | 1 |
| Bode, HR; Teragawa, CK | 1 |
| Bode, HR; Heimfeld, S | 3 |
| Bode, HR; Littlefield, CL | 1 |
| Heimfeld, S | 1 |
| Littlefield, CL | 1 |
| Hamilton, S; Webster, G | 1 |
| MacWilliams, HK | 1 |
| David, CN; Fujisawa, T | 1 |
| Bode, HR; Shimizu, H | 1 |
| Nishimiya-Fujisawa, C; Sugiyama, T | 1 |
| Buzgariu, W; Catunda-Lemos, AP; Galliot, B; Tcaciuc, N; Wenger, Y | 1 |
| Buzgariu, W; Curchod, ML; Galliot, B; Perruchoud, C | 1 |
1 review(s) available for hydroxyurea and isoniazid
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
32 other study(ies) available for hydroxyurea and isoniazid
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents, IV: The mechanisms involved in inhibiting cell-cycle progression.
Topics: Antineoplastic Agents; Cell Cycle; Cyclins; Deferoxamine; Female; Genes, Retinoblastoma; Humans; Hydroxyurea; Iron; Iron Chelating Agents; Isoniazid; Pyridoxal; Structure-Activity Relationship; Tumor Cells, Cultured | 2001 |
Inhibition of malignant cell growth by 311, a novel iron chelator of the pyridoxal isonicotinoyl hydrazone class: effect on the R2 subunit of ribonucleotide reductase.
Topics: Antineoplastic Agents; Cell Division; Deferoxamine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Humans; Hydroxyurea; Iron Chelating Agents; Isoniazid; Mutation; Protein Subunits; Ribonucleotide Reductases; Time Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2001 |
Production of nerveless Hydra attenuata by hydroxyurea treatments.
Topics: Animals; Cell Count; Hydra; Hydroxyurea; Microscopy, Electron; Neurons; Regeneration | 1979 |
Regulation of interstitial cell differentiation in Hydra attenuata. III. Effects of I-cell and nerve cell densities.
Topics: Animals; Cell Count; Cell Differentiation; Feedback; Hydra; Hydroxyurea; Mitosis; Neurons | 1978 |
Regulation of interstitial cell differentiation in Hydra attenuata. I. Homeostatic control of interstitial cell population size.
Topics: Animals; Cell Differentiation; Cell Division; Colchicine; DNA; Hydra; Hydroxyurea | 1976 |
Homeostatic recovery of interstitial cell populations in Hydra.
Topics: Animals; Cell Cycle; Chimera; Homeostasis; Hydra; Hydroxyurea; Stem Cell Transplantation; Stem Cells | 1992 |
Cell lineages in Hydra: isolation and characterization of an interstitial stem cell restricted to egg production in Hydra oligactis.
Topics: Animals; Female; Hydra; Hydroxyurea; Male; Oogenesis; Ovum; Sex Determination Analysis; Spermatozoa; Stem Cells; Temperature | 1991 |
Plasticity in the nervous system of adult hydra. III. Conversion of neurons to expression of a vasopressin-like immunoreactivity depends on axial location.
Topics: Animals; Cell Count; Cell Differentiation; Hydra; Hydroxyurea; Immunohistochemistry; Mechlorethamine; Nervous System; Neuronal Plasticity; Neurons; Stem Cells; Vasopressins | 1991 |
Spatial and temporal patterns of interstitial cell migration in Hydra vulgaris.
Topics: Animals; Bromodeoxyuridine; Cell Movement; Hydra; Hydroxyurea; Morphogenesis | 1990 |
Growth regulation of the interstitial cell population in hydra. III. Interstitial cell density does not control stem cell proliferation.
Topics: Animals; Cell Count; Cell Differentiation; Cell Division; Clone Cells; Hydra; Hydroxyurea; Models, Biological; Stem Cells | 1986 |
Growth regulation of the interstitial cell population in hydra. IV. Control of nerve cell and nematocyte differentiation by amplification of non-stem interstitial cells.
Topics: Animals; Cell Differentiation; Cell Division; Hydra; Hydroxyurea; Mechlorethamine; Neurons | 1986 |
Germ cells in Hydra oligactis males. II. Evidence for a subpopulation of interstitial stem cells whose differentiation is limited to sperm production.
Topics: Animals; Cell Differentiation; Cell Division; Germ Cells; Hydra; Hydroxyurea; Male; Spermatogenesis; Temperature | 1986 |
Growth regulation of the interstitial cell population in hydra. I. Evidence for global control by nerve cells in the head.
Topics: Animals; Cell Division; Cell Movement; Epithelial Cells; Head; Hydra; Hydroxyurea; Neurons; Stem Cells | 1985 |
Growth regulation of the interstitial cell population in hydra. II. A new mechanism for the homeostatic recovery of reduced interstitial cell populations.
Topics: Animals; Cell Division; Cell Survival; Epithelial Cells; Homeostasis; Hydra; Hydroxyurea; Kinetics; Mathematics | 1985 |
Germ cells in Hydra oligactis males. I. Isolation of a subpopulation of interstitial cells that is developmentally restricted to sperm production.
Topics: Animals; Cell Differentiation; Clone Cells; Germ Cells; Hydra; Hydroxyurea; Male; Spermatogenesis | 1985 |
Budding in hydra: the role of cell multiplication and cell movement in bud initiation.
Topics: Animals; Cell Count; Cell Movement; DNA; Food Deprivation; Hydra; Hydroxyurea; Mitosis; Thymidine; Transplantation, Homologous; Tritium | 1972 |
Hydra transplantation phenomena and the mechanism of Hydra head regeneration. II. Properties of the head activation.
Topics: Animals; Hydra; Hydroxyurea; Kinetics; Models, Biological; Regeneration; Transplantation, Autologous | 1983 |
Commitment during stenotele differentiation in Hydra is localized near the S/G2 boundary in the terminal cell cycle.
Topics: Animals; Cell Differentiation; Hydra; Hydroxyurea; Interphase; Kinetics; Regeneration | 1982 |
Developmental dominance in hydra. I. The basal disk.
Topics: Animals; Hydra; Hydroxyurea; Nervous System; Nervous System Physiological Phenomena; Transplantation, Heterologous; Transplantation, Homologous | 1980 |
Nematocyte differentiation in hydra: commitment to nematocyte type occurs at the beginning of the pathway.
Topics: Animals; Cell Cycle; Cell Differentiation; Female; Hydra; Hydroxyurea; Staining and Labeling; Statistics as Topic; Stem Cells; Time Factors | 1995 |
Genetic analysis of developmental mechanisms in Hydra. XXII. Two types of female germ stem cells are present in a male strain of Hydra magnipapillata.
Topics: Animals; Bromodeoxyuridine; Cell Movement; Epithelium; Female; Germ Cells; Hydra; Hydroxyurea; Male; Sex Characteristics; Sex Differentiation; Stem Cells | 1995 |
Impact of cycling cells and cell cycle regulation on Hydra regeneration.
Topics: Animals; Cell Cycle; Cell Division; Flow Cytometry; Gene Expression Profiling; Gene Expression Regulation; Genes, cdc; Hydra; Hydroxyurea; Nocodazole; Regeneration; S Phase; Stem Cells; Transcriptome | 2018 |
Combining BrdU-Labeling to Detection of Neuronal Markers to Monitor Adult Neurogenesis in Hydra.
Topics: Animals; Bromodeoxyuridine; Fluorescent Antibody Technique; Gene Expression Regulation, Developmental; Hydra; Hydroxyurea; In Situ Hybridization; Neurogenesis; Stem Cells | 2020 |