hydroxyurea and isoniazid

hydroxyurea has been researched along with isoniazid in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199013 (39.39)18.7374
1990's6 (18.18)18.2507
2000's5 (15.15)29.6817
2010's8 (24.24)24.3611
2020's1 (3.03)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Gao, J; Richardson, DR1
Antholine, WE; Chitambar, CR; Green, DA; Richardson, DR; Wong, SJ1
Davis, LE; Sacks, PG2
Bode, HR; Yaross, MS1
Bode, HR; Flick, KM; Smith, GS1
Fujisawa, T1
Littefield, CL1
Bode, HR; Koizumi, O1
Bode, HR; Teragawa, CK1
Bode, HR; Heimfeld, S3
Bode, HR; Littlefield, CL1
Heimfeld, S1
Littlefield, CL1
Hamilton, S; Webster, G1
MacWilliams, HK1
David, CN; Fujisawa, T1
Bode, HR; Shimizu, H1
Nishimiya-Fujisawa, C; Sugiyama, T1
Buzgariu, W; Catunda-Lemos, AP; Galliot, B; Tcaciuc, N; Wenger, Y1
Buzgariu, W; Curchod, ML; Galliot, B; Perruchoud, C1

Reviews

1 review(s) available for hydroxyurea and isoniazid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

32 other study(ies) available for hydroxyurea and isoniazid

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents, IV: The mechanisms involved in inhibiting cell-cycle progression.
    Blood, 2001, Aug-01, Volume: 98, Issue:3

    Topics: Antineoplastic Agents; Cell Cycle; Cyclins; Deferoxamine; Female; Genes, Retinoblastoma; Humans; Hydroxyurea; Iron; Iron Chelating Agents; Isoniazid; Pyridoxal; Structure-Activity Relationship; Tumor Cells, Cultured

2001
Inhibition of malignant cell growth by 311, a novel iron chelator of the pyridoxal isonicotinoyl hydrazone class: effect on the R2 subunit of ribonucleotide reductase.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:11

    Topics: Antineoplastic Agents; Cell Division; Deferoxamine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Humans; Hydroxyurea; Iron Chelating Agents; Isoniazid; Mutation; Protein Subunits; Ribonucleotide Reductases; Time Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2001
Production of nerveless Hydra attenuata by hydroxyurea treatments.
    Journal of cell science, 1979, Volume: 37

    Topics: Animals; Cell Count; Hydra; Hydroxyurea; Microscopy, Electron; Neurons; Regeneration

1979
Regulation of interstitial cell differentiation in Hydra attenuata. III. Effects of I-cell and nerve cell densities.
    Journal of cell science, 1978, Volume: 34

    Topics: Animals; Cell Count; Cell Differentiation; Feedback; Hydra; Hydroxyurea; Mitosis; Neurons

1978
Regulation of interstitial cell differentiation in Hydra attenuata. I. Homeostatic control of interstitial cell population size.
    Journal of cell science, 1976, Volume: 20, Issue:1

    Topics: Animals; Cell Differentiation; Cell Division; Colchicine; DNA; Hydra; Hydroxyurea

1976
Homeostatic recovery of interstitial cell populations in Hydra.
    Developmental biology, 1992, Volume: 150, Issue:1

    Topics: Animals; Cell Cycle; Chimera; Homeostasis; Hydra; Hydroxyurea; Stem Cell Transplantation; Stem Cells

1992
Cell lineages in Hydra: isolation and characterization of an interstitial stem cell restricted to egg production in Hydra oligactis.
    Developmental biology, 1991, Volume: 143, Issue:2

    Topics: Animals; Female; Hydra; Hydroxyurea; Male; Oogenesis; Ovum; Sex Determination Analysis; Spermatozoa; Stem Cells; Temperature

1991
Plasticity in the nervous system of adult hydra. III. Conversion of neurons to expression of a vasopressin-like immunoreactivity depends on axial location.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1991, Volume: 11, Issue:7

    Topics: Animals; Cell Count; Cell Differentiation; Hydra; Hydroxyurea; Immunohistochemistry; Mechlorethamine; Nervous System; Neuronal Plasticity; Neurons; Stem Cells; Vasopressins

1991
Spatial and temporal patterns of interstitial cell migration in Hydra vulgaris.
    Developmental biology, 1990, Volume: 138, Issue:1

    Topics: Animals; Bromodeoxyuridine; Cell Movement; Hydra; Hydroxyurea; Morphogenesis

1990
Growth regulation of the interstitial cell population in hydra. III. Interstitial cell density does not control stem cell proliferation.
    Developmental biology, 1986, Volume: 116, Issue:1

    Topics: Animals; Cell Count; Cell Differentiation; Cell Division; Clone Cells; Hydra; Hydroxyurea; Models, Biological; Stem Cells

1986
Growth regulation of the interstitial cell population in hydra. IV. Control of nerve cell and nematocyte differentiation by amplification of non-stem interstitial cells.
    Developmental biology, 1986, Volume: 116, Issue:1

    Topics: Animals; Cell Differentiation; Cell Division; Hydra; Hydroxyurea; Mechlorethamine; Neurons

1986
Germ cells in Hydra oligactis males. II. Evidence for a subpopulation of interstitial stem cells whose differentiation is limited to sperm production.
    Developmental biology, 1986, Volume: 116, Issue:2

    Topics: Animals; Cell Differentiation; Cell Division; Germ Cells; Hydra; Hydroxyurea; Male; Spermatogenesis; Temperature

1986
Growth regulation of the interstitial cell population in hydra. I. Evidence for global control by nerve cells in the head.
    Developmental biology, 1985, Volume: 110, Issue:2

    Topics: Animals; Cell Division; Cell Movement; Epithelial Cells; Head; Hydra; Hydroxyurea; Neurons; Stem Cells

1985
Growth regulation of the interstitial cell population in hydra. II. A new mechanism for the homeostatic recovery of reduced interstitial cell populations.
    Developmental biology, 1985, Volume: 111, Issue:2

    Topics: Animals; Cell Division; Cell Survival; Epithelial Cells; Homeostasis; Hydra; Hydroxyurea; Kinetics; Mathematics

1985
Germ cells in Hydra oligactis males. I. Isolation of a subpopulation of interstitial cells that is developmentally restricted to sperm production.
    Developmental biology, 1985, Volume: 112, Issue:1

    Topics: Animals; Cell Differentiation; Clone Cells; Germ Cells; Hydra; Hydroxyurea; Male; Spermatogenesis

1985
Budding in hydra: the role of cell multiplication and cell movement in bud initiation.
    Journal of embryology and experimental morphology, 1972, Volume: 27, Issue:2

    Topics: Animals; Cell Count; Cell Movement; DNA; Food Deprivation; Hydra; Hydroxyurea; Mitosis; Thymidine; Transplantation, Homologous; Tritium

1972
Hydra transplantation phenomena and the mechanism of Hydra head regeneration. II. Properties of the head activation.
    Developmental biology, 1983, Volume: 96, Issue:1

    Topics: Animals; Hydra; Hydroxyurea; Kinetics; Models, Biological; Regeneration; Transplantation, Autologous

1983
Commitment during stenotele differentiation in Hydra is localized near the S/G2 boundary in the terminal cell cycle.
    Developmental biology, 1982, Volume: 93, Issue:1

    Topics: Animals; Cell Differentiation; Hydra; Hydroxyurea; Interphase; Kinetics; Regeneration

1982
Developmental dominance in hydra. I. The basal disk.
    Developmental biology, 1980, Volume: 80, Issue:2

    Topics: Animals; Hydra; Hydroxyurea; Nervous System; Nervous System Physiological Phenomena; Transplantation, Heterologous; Transplantation, Homologous

1980
Nematocyte differentiation in hydra: commitment to nematocyte type occurs at the beginning of the pathway.
    Developmental biology, 1995, Volume: 169, Issue:1

    Topics: Animals; Cell Cycle; Cell Differentiation; Female; Hydra; Hydroxyurea; Staining and Labeling; Statistics as Topic; Stem Cells; Time Factors

1995
Genetic analysis of developmental mechanisms in Hydra. XXII. Two types of female germ stem cells are present in a male strain of Hydra magnipapillata.
    Developmental biology, 1995, Volume: 172, Issue:1

    Topics: Animals; Bromodeoxyuridine; Cell Movement; Epithelium; Female; Germ Cells; Hydra; Hydroxyurea; Male; Sex Characteristics; Sex Differentiation; Stem Cells

1995
Impact of cycling cells and cell cycle regulation on Hydra regeneration.
    Developmental biology, 2018, 01-15, Volume: 433, Issue:2

    Topics: Animals; Cell Cycle; Cell Division; Flow Cytometry; Gene Expression Profiling; Gene Expression Regulation; Genes, cdc; Hydra; Hydroxyurea; Nocodazole; Regeneration; S Phase; Stem Cells; Transcriptome

2018
Combining BrdU-Labeling to Detection of Neuronal Markers to Monitor Adult Neurogenesis in Hydra.
    Methods in molecular biology (Clifton, N.J.), 2020, Volume: 2047

    Topics: Animals; Bromodeoxyuridine; Fluorescent Antibody Technique; Gene Expression Regulation, Developmental; Hydra; Hydroxyurea; In Situ Hybridization; Neurogenesis; Stem Cells

2020