hydroxyurea and isomethyleugenol

hydroxyurea has been researched along with isomethyleugenol in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199028 (75.68)18.7374
1990's1 (2.70)18.2507
2000's2 (5.41)29.6817
2010's6 (16.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Freeman-Narrod, M1
Debov, SS; Mushkambarov, NN; Votrin, II1
Hudson, JL; Liebling, MR; Richardson, BC1
DeSimone, J; Hall, L; Heller, P; Lavelle, D; Zwiers, D1
Frahm, J; Hoshino, J; Kröger, H1
Charache, S; Dover, GJ1
Alvarez, E; Elliott, BE; Houghton, AN; Kerbel, RS1
Bare, RM; McDowell, AE; Miller, MS; Waalkes, MP; Wilson, MJ1
Pfeifer, GP; Steigerwald, SD1
Cano, C; Herrera-Estrella, L; Ruiz-Herrera, J1
Ley, TJ; Nienhuis, AW1
Kerbel, RS; Liteplo, RG1
Jones, PA; Liu, L; Nyce, J1
Krauss, G; Probst, H; Ullrich, A1
Krijzer, FN; Moors, J; Wanka, F1
Potten, CS1
Isensee, G; Zinner, G1
Grunicke, H; Puschendorf, B1
Adams, RL1
Adams, RL; Burdon, RH1
DeSimone, J; Hall, L; Heller, P; Zwiers, D1
Kolata, G1
Jost, JP; Seldran, M; Wilks, A1
Beardsley, GP; Letvin, NL; Linch, DC; McIntyre, KW; Nathan, DG1
Adamson, JW1
Beardsley, GP; Dover, G; Miller, B; Nathan, DG; Orkin, SH; Platt, OS1
Norry, TW; Schrader, TJ; Th'ng, JP; Walker, IG1
Vasil'ev, VK1
Kornacka, L; Malec, J; Sawecka, J1
Baldacci, G; Collura, A; Francesconi, S; Géli, V; Ishikawa, F; Kanoh, J; Schramke, V1
Dutt, S; Graves, K; Juszczynski, P; Manis, JP; Shipp, MA; Xu, R; Yan, Q1
Ciccia, A; Elledge, SJ; Hajdu, I; Lewis, SM1
Chen, S; Wang, W; Xu, M; Zhu, B1
Biruš, M; Sakić, D; Vrček, IV; Vrček, V; Zipse, H1
Ansbro, MR; Boudoures, AL; Cole, AM; Karl, AL; Mecoli, JP; Rossodivita, AA; Steenkiste, EM; Thompson, JS; Vines, EM1
DeSimone, J; Ibanez, V; Jagadeeswaran, R; Kouznetsova, T; Lavelle, D; Rivers, A; Ruiz, MA; Vaitkus, K1
Hromas, R; Kim, HS; Kim, SK; Lee, SH1

Reviews

1 review(s) available for hydroxyurea and isomethyleugenol

ArticleYear
Induction of hemoglobin F synthesis in patients with beta thalassemia.
    Annual review of medicine, 1985, Volume: 36

    Topics: Animals; Azacitidine; DNA; Erythroblasts; Female; Fetal Hemoglobin; Gene Expression Regulation; Globins; Humans; Hydroxyurea; Methylation; Papio; Thalassemia

1985

Trials

1 trial(s) available for hydroxyurea and isomethyleugenol

ArticleYear
Hydroxyurea enhances fetal hemoglobin production in sickle cell anemia.
    The Journal of clinical investigation, 1984, Volume: 74, Issue:2

    Topics: Adolescent; Adult; Anemia, Sickle Cell; Bone Marrow; Clinical Trials as Topic; DNA; Female; Fetal Hemoglobin; Granulocytes; Hematopoietic Stem Cells; Humans; Hydroxyurea; Leukocyte Count; Methylation

1984

Other Studies

35 other study(ies) available for hydroxyurea and isomethyleugenol

ArticleYear
Choline antagonism of methotrexate liver toxicity in the rat.
    Medical and pediatric oncology, 1977, Volume: 3, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Choline; Hydroxyurea; Liver; Liver Diseases; Male; Methotrexate; Methylation; Rats; Triglycerides

1977
[Methylation of preformed DNA in rat liver cell nuclei and mitochondria].
    Doklady Akademii nauk SSSR, 1976, Volume: 229, Issue:5

    Topics: Animals; Cell Nucleus; Depression, Chemical; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Mitochondrial; Hydroxyurea; Liver; Liver Regeneration; Methylation; Mitochondria, Liver; Rats

1976
CD4+ cells treated with DNA methylation inhibitors induce autologous B cell differentiation.
    Clinical immunology and immunopathology, 1990, Volume: 55, Issue:3

    Topics: Acecainide; Antibody Formation; Antigen-Presenting Cells; Antigens, CD; Antigens, Differentiation; Azacitidine; B-Lymphocytes; CD4-Positive T-Lymphocytes; Cell Differentiation; DNA; Histocompatibility Antigens; Humans; Hydroxyurea; Integrin beta1; Leukocyte Common Antigens; Methylation; Procainamide

1990
On the mechanism of Hb F elevations in the baboon by erythropoietic stress and pharmacologic manipulation.
    Blood, 1986, Volume: 67, Issue:4

    Topics: Anemia, Hemolytic; Animals; Azacitidine; Cytarabine; DNA; Erythropoiesis; Fetal Hemoglobin; Hemorrhage; Hydroxyurea; Leukocyte Count; Methylation; Nucleic Acid Hybridization; Papio; Reticulocytes

1986
Suppression of nuclear ADP-ribosyltransferase activity in Ehrlich ascites tumor cells by 5-azacytidine and its analogs.
    Biochemical and biophysical research communications, 1987, Jan-30, Volume: 142, Issue:2

    Topics: Animals; Azacitidine; Carcinoma, Ehrlich Tumor; Cell Nucleus; Cytosine; DNA; Female; Hydroxyurea; Methylation; Mice; Mice, Inbred Strains; Poly(ADP-ribose) Polymerase Inhibitors

1987
Increasing fetal hemoglobin production in sickle cell disease: results of clinical trials.
    Progress in clinical and biological research, 1987, Volume: 251

    Topics: Anemia, Sickle Cell; Azacitidine; DNA; Fetal Hemoglobin; Hematopoietic Stem Cells; Humans; Hydroxyurea; Methylation; Reticulocytes

1987
Heritable high frequency modulation of antigen expression in neoplastic cells exposed to 5-aza-2'-deoxycytidine or hydroxyurea: analysis and implications.
    Cancer research, 1988, May-01, Volume: 48, Issue:9

    Topics: Animals; Antigens, Neoplasm; Azacitidine; Decitabine; DNA, Neoplasm; Histocompatibility Antigens; Humans; Hydroxyurea; Mammary Neoplasms, Experimental; Melanoma, Experimental; Methylation; Mice; Tumor Cells, Cultured

1988
Increased metallothionein gene expression in 5-aza-2'-deoxycytidine-induced resistance to cadmium cytotoxicity.
    Chemico-biological interactions, 1988, Volume: 66, Issue:3-4

    Topics: Animals; Azacitidine; Cadmium; Cell Line; Cell Survival; Decitabine; DNA; DNA Restriction Enzymes; Dose-Response Relationship, Drug; Drug Resistance; Gene Expression Regulation; Hydroxyurea; Kinetics; Liver; Metallothionein; Methylation; Nucleic Acid Hybridization; Rats; Rats, Inbred F344

1988
Variable DNA methylation changes during differentiation of human melanoma cells.
    Experimental cell research, 1988, Volume: 178, Issue:1

    Topics: Aphidicolin; Azacitidine; Cell Differentiation; Cell Division; Chromatography, High Pressure Liquid; Cytarabine; Decitabine; Diterpenes; DNA; DNA, Neoplasm; Humans; Hydroxyurea; Methylation; Monophenol Monooxygenase; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1988
DNA methylation and polyamines in regulation of development of the fungus Mucor rouxii.
    Journal of bacteriology, 1988, Volume: 170, Issue:12

    Topics: Azacitidine; DNA, Fungal; Hydroxyurea; Methylation; Mucor; Polyamines; Putrescine; Spores, Fungal

1988
Periodate-oxidized adenosine induction of murine thymidine kinase: role of DNA methylation in the generation of tumor cell heterogeneity.
    Cancer research, 1986, Volume: 46, Issue:2

    Topics: 5-Methylcytosine; Adenosine; Animals; Cells, Cultured; Cytosine; DNA, Neoplasm; Enzyme Induction; Hydroxyurea; Methylation; Mice; Oxidation-Reduction; Periodic Acid; Thymidine Kinase

1986
Variable effects of DNA-synthesis inhibitors upon DNA methylation in mammalian cells.
    Nucleic acids research, 1986, May-27, Volume: 14, Issue:10

    Topics: Animals; Aphidicolin; Base Sequence; Cell Line; Chromatography, High Pressure Liquid; Cricetinae; Cycloheximide; Cytarabine; Dactinomycin; Diterpenes; DNA; DNA Polymerase II; DNA Replication; Fibrosarcoma; Hydroxyurea; Methylation; Nalidixic Acid; Novobiocin

1986
Newly synthesized mammalian cell DNA: studies on the reasons for the increased affinity to nitrocellulose.
    Biochimica et biophysica acta, 1971, Nov-29, Volume: 254, Issue:1

    Topics: Alcohols; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cellulose; Centrifugation, Density Gradient; Chloroform; Chromatography; Detergents; DNA; DNA, Neoplasm; Hydrogen-Ion Concentration; Hydroxyapatites; Hydroxyurea; Methylation; Mice; Nitro Compounds; Osmolar Concentration; Serum Albumin; Silicon Dioxide; Solubility; Sulfuric Acids; Thymidine; Tritium; Uridine

1971
Dissociation of nuclear DNA replication from concomitant protein synthesis in synchronous cultures of Chlorella.
    Biochimica et biophysica acta, 1972, Apr-26, Volume: 269, Issue:1

    Topics: Carbon Isotopes; Centrifugation, Density Gradient; Chlorella; Chlorophyta; Chromatography; Cycloheximide; Darkness; DNA; DNA Replication; Hydroxyurea; Light; Methylation; Protein Biosynthesis; Radiation Effects; RNA; Serum Albumin; Silicon Dioxide; Time Factors; Uracil

1972
Further observations on the late labelling associated with stimulus-responsive cells in skin.
    Cell and tissue kinetics, 1973, Volume: 6, Issue:6

    Topics: Animals; Autoradiography; Cell Division; DNA; Hydroxyurea; Injections, Intraperitoneal; Iodine Radioisotopes; Male; Methylation; Mice; Mice, Inbred DBA; Physical Stimulation; Skin; Thymidine; Time Factors; Tritium; Uridine

1973
[Synthesis and acylations of 1.1-dialkyl-3-hydroxyureas (author's transl)].
    Archiv der Pharmazie, 1974, Volume: 307, Issue:1

    Topics: Acylation; Hydroxylamines; Hydroxyurea; Methylation

1974
Effect of hydroxyurea and trisethyleneiminobenzoquinone (Trenimon) on the methylation of DNA in Ehrlich ascites tumor cells.
    Biochimica et biophysica acta, 1972, Jun-22, Volume: 272, Issue:1

    Topics: Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Chromatography, Paper; Cytidine; Cytosine Nucleotides; Depression, Chemical; DNA, Neoplasm; Hydroxyurea; Mathematics; Methionine; Methylation; Mice; Thymidine; Triaziquone; Tritium

1972
Methylation of newly synthesized and older deoxyribonucleic acid.
    The Biochemical journal, 1971, Volume: 123, Issue:4

    Topics: Animals; Bromodeoxyuridine; Cell Line; DNA; Horses; Hydroxyurea; Lectins; Lymphocytes; Methionine; Methylation; Mice; Phosphates; Phosphorus Isotopes; Tritium

1971
The in vivo methylation of DNA in mouse fibroblasts.
    Biochimica et biophysica acta, 1969, Jan-21, Volume: 174, Issue:1

    Topics: Animals; Colorimetry; Culture Techniques; Cytosine; Depression, Chemical; DNA; DNA Replication; Drug Stability; Fibroblasts; Hydroxyurea; L Cells; Methionine; Methylation; Mice; Mitosis; Protein Biosynthesis; Pyrimidines; Thymidine; Time Factors; Tritium

1969
5-Azacytidine stimulates fetal hemoglobin synthesis in anemic baboons.
    Proceedings of the National Academy of Sciences of the United States of America, 1982, Volume: 79, Issue:14

    Topics: Animals; Azacitidine; Fetal Hemoglobin; Gene Expression Regulation; Globins; Hematopoiesis; Hemoglobin A; Hydroxyurea; Methylation; Papio

1982
Globin gene studies create a puzzle.
    Science (New York, N.Y.), 1984, Feb-03, Volume: 223, Issue:4635

    Topics: Anemia, Sickle Cell; Azacitidine; Cell Differentiation; Cytarabine; DNA; Erythropoiesis; Fetal Hemoglobin; Gene Expression Regulation; Hematopoietic Stem Cells; Humans; Hydroxyurea; Interphase; Methylation

1984
An estrogen-dependent demethylation at the 5' end of the chicken vitellogenin gene is independent of DNA synthesis.
    Nucleic acids research, 1984, Jan-25, Volume: 12, Issue:2

    Topics: Animals; Chickens; Cytarabine; Deoxyribonuclease HpaII; DNA; DNA Replication; DNA Restriction Enzymes; Estradiol; Female; Genes; Hydroxyurea; Lipoproteins; Liver; Male; Methylation; Nucleic Acid Hybridization; RNA, Messenger; Vitellogenins

1984
Augmentation of fetal-hemoglobin production in anemic monkeys by hydroxyurea.
    The New England journal of medicine, 1984, Apr-05, Volume: 310, Issue:14

    Topics: Anemia; Animals; Azacitidine; Bloodletting; DNA; Erythrocyte Count; Fetal Hemoglobin; Globins; Hydroxyurea; Macaca fascicularis; Methylation; Transcription, Genetic

1984
Hemoglobin--from F to A, and back.
    The New England journal of medicine, 1984, Apr-05, Volume: 310, Issue:14

    Topics: Anemia, Sickle Cell; Azacitidine; DNA; Fetal Hemoglobin; Humans; Hydroxyurea; Methylation; Thalassemia

1984
3-Aminobenzamide does not increase repair patch size in mammalian cells.
    Canadian journal of biochemistry and cell biology = Revue canadienne de biochimie et biologie cellulaire, 1984, Volume: 62, Issue:6

    Topics: Benzamides; Cells, Cultured; DNA Repair; Humans; Hydroxyurea; Methylation; Sulfuric Acid Esters

1984
[Effect of cortisol on repair synthesis and methylation of DNA of rat liver].
    Biulleten' eksperimental'noi biologii i meditsiny, 1982, Volume: 94, Issue:11

    Topics: Animals; Base Sequence; DNA; DNA Repair; Hydrocortisone; Hydroxyurea; Liver; Male; Methylation; Rats; Rats, Inbred Strains

1982
Distribution of DNA repair and the extent of enzymatic DNA methylation in alkylated human lymphocytes carrying their DNA synthesis in the presence or absence of hydroxyurea.
    Biochemical and biophysical research communications, 1980, Jul-16, Volume: 95, Issue:1

    Topics: Cytosine; Deoxyribonucleases; DNA; DNA Repair; Humans; Hydroxyurea; Lymphocytes; Mechlorethamine; Methylation; Oligodeoxyribonucleotides

1980
The fission yeast spSet1p is a histone H3-K4 methyltransferase that functions in telomere maintenance and DNA repair in an ATM kinase Rad3-dependent pathway.
    Journal of molecular biology, 2003, Feb-28, Volume: 326, Issue:4

    Topics: Antineoplastic Agents; Cell Cycle Proteins; Cell Survival; Centromere; Checkpoint Kinase 2; DNA Damage; DNA Repair; DNA-Binding Proteins; Gene Silencing; Genes, cdc; Histone-Lysine N-Methyltransferase; Histones; Humans; Hydroxyurea; Methylation; Methyltransferases; Protein Kinases; Saccharomyces cerevisiae Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Telomere; Transcription Factors; Ultraviolet Rays

2003
BBAP monoubiquitylates histone H4 at lysine 91 and selectively modulates the DNA damage response.
    Molecular cell, 2009, Oct-09, Volume: 36, Issue:1

    Topics: Acetylation; Apoptosis; Cell Line; Cell Proliferation; DNA Damage; Doxorubicin; HeLa Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Hydroxyurea; Intracellular Signaling Peptides and Proteins; Lysine; Methylation; Nucleosomes; Protein Binding; Protein Processing, Post-Translational; Recombinant Proteins; RNA, Small Interfering; Tumor Suppressor p53-Binding Protein 1; Ubiquitin; Ubiquitin-Protein Ligases; Ubiquitination

2009
Wolf-Hirschhorn syndrome candidate 1 is involved in the cellular response to DNA damage.
    Proceedings of the National Academy of Sciences of the United States of America, 2011, Aug-09, Volume: 108, Issue:32

    Topics: Cell Line, Tumor; Checkpoint Kinase 2; DNA Damage; DNA Replication; Enzyme Activation; Gene Silencing; Histone-Lysine N-Methyltransferase; Histones; Humans; Hydroxyurea; Intracellular Signaling Peptides and Proteins; Lysine; Methylation; Phosphorylation; Protein Serine-Threonine Kinases; Protein Transport; Replication Protein A; Repressor Proteins; Stress, Physiological; Tumor Suppressor p53-Binding Protein 1; Wolf-Hirschhorn Syndrome

2011
A model for mitotic inheritance of histone lysine methylation.
    EMBO reports, 2011, Dec-23, Volume: 13, Issue:1

    Topics: Cell Cycle; Cell Cycle Checkpoints; Epigenesis, Genetic; HeLa Cells; Histones; Humans; Hydroxyurea; Lysine; Methylation; Mitosis; Models, Biological

2011
Computational study of radicals derived from hydroxyurea and its methylated analogues.
    Organic & biomolecular chemistry, 2012, Feb-14, Volume: 10, Issue:6

    Topics: Free Radicals; Hydroxyurea; Methylation; Quantum Theory; Thermodynamics

2012
Histone H3 K79 methylation states play distinct roles in UV-induced sister chromatid exchange and cell cycle checkpoint arrest in Saccharomyces cerevisiae.
    Nucleic acids research, 2014, Volume: 42, Issue:10

    Topics: DNA Breaks, Double-Stranded; DNA Damage; DNA Repair; G1 Phase Cell Cycle Checkpoints; Histones; Hydroxyurea; Methylation; Saccharomyces cerevisiae; Sister Chromatid Exchange; Ubiquitination; Ultraviolet Rays

2014
RN-1, a potent and selective lysine-specific demethylase 1 inhibitor, increases γ-globin expression, F reticulocytes, and F cells in a sickle cell disease mouse model.
    Experimental hematology, 2015, Volume: 43, Issue:7

    Topics: Anemia, Sickle Cell; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Inhibitors; Erythroid Precursor Cells; Erythropoiesis; Fetal Hemoglobin; gamma-Globins; Gene Expression Regulation; Hematopoietic Stem Cells; Histone Demethylases; Histones; Humans; Hydroxyurea; Methylation; Mice; Mice, Transgenic; Papio; Protein Processing, Post-Translational; Reticulocytes; Transgenes; Tranylcypromine; Tretinoin; U937 Cells

2015
The SET Domain Is Essential for Metnase Functions in Replication Restart and the 5' End of SS-Overhang Cleavage.
    PloS one, 2015, Volume: 10, Issue:10

    Topics: Base Sequence; DNA Damage; DNA End-Joining Repair; DNA Replication; DNA, Single-Stranded; HEK293 Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Hydroxyurea; Lysine; Methylation; Molecular Sequence Data; Oxidoreductases, N-Demethylating; Protein Processing, Post-Translational; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Deletion

2015