hydroxyurea and indinavir sulfate

hydroxyurea has been researched along with indinavir sulfate in 21 studies

Research

Studies (21)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	6 (28.57)	18.2507
2000's	8 (38.10)	29.6817
2010's	6 (28.57)	24.3611
2020's	1 (4.76)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Finzi, D; Jessen, H; Lisziewicz, J; Lori, F; Siliciano, RF	1
Clerici, M; Jessen, H; Lieberman, J; Lisziewicz, J; Lori, F; Tinelli, C	1
Finzi, D; Jessen, H; Lieberman, J; Lisziewicz, J; Lori, F; Rosenberg, E; Siliciano, RF; Tinelli, C; Walker, B	1
Busch, M; Hecht, FM; Kahn, J; Levy, JA; Martinez-Marino, B; Ong, JC; Stranford, SA	1
Mascolini, M	1
Adams, EM; Bennett, K; Collier, AC; Gilbert, PB; Goodwin, D; Havlir, DV; Hirsch, MS; Holohan, MK; Richman, DD; Schnittman, S; Tebas, P; Wheat, LJ	1
Comolli, G; Foli, A; Lisziewicz, J; Lori, F; Piccinini, G	1
Barasolo, G; Castelli, F; D'Aquila, R; Foli, A; Lisziewicz, J; Lori, F; Maggiolo, F; Maserati, R; Migliorino, M; Pan, A; Paolucci, S; Scudeller, L; Tinelli, C; Tomasoni, L	1
Murphy, RL; Parker, RA; Redfield, RR; Reisler, RB	1
Ekins, S; Williams, AJ; Xu, JJ	1

Reviews

1 review(s) available for hydroxyurea and indinavir sulfate

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

5 trial(s) available for hydroxyurea and indinavir sulfate

Article	Year
Immune restoration by combination of a cytostatic drug (hydroxyurea) and anti-HIV drugs (didanosine and indinavir). AIDS research and human retroviruses, 1999, May-01, Volume: 15, Issue:7 Topics: Anti-HIV Agents; CD3 Complex; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Hydroxyurea; Indinavir; Lymphocyte Activation; Nucleic Acid Synthesis Inhibitors; Reverse Transcriptase Inhibitors; Viremia	1999
Treatment of human immunodeficiency virus infection with hydroxyurea, didanosine, and a protease inhibitor before seroconversion is associated with normalized immune parameters and limited viral reservoir. The Journal of infectious diseases, 1999, Volume: 180, Issue:6 Topics: Anti-HIV Agents; Blotting, Western; CD4 Lymphocyte Count; CD4-CD8 Ratio; CD8-Positive T-Lymphocytes; Didanosine; Drug Therapy, Combination; Flow Cytometry; HIV Antibodies; HIV Infections; HIV Protease Inhibitors; Humans; Hydroxyurea; Indinavir; Lymphocyte Activation; Viral Load	1999
Effects of treatment intensification with hydroxyurea in HIV-infected patients with virologic suppression. AIDS (London, England), 2001, Jul-27, Volume: 15, Issue:11 Topics: Adolescent; Adult; Anti-HIV Agents; Case-Control Studies; CD4 Lymphocyte Count; Drug Therapy, Combination; Enzyme Inhibitors; Female; HIV Infections; Humans; Hydroxyurea; Indinavir; Lamivudine; Male; Nucleic Acid Synthesis Inhibitors; Pancreatitis; Prospective Studies; Survival Analysis; Treatment Failure; Viral Load; Zidovudine	2001
Strategies to decrease viral load rebound, and prevent loss of CD4 and onset of resistance during structured treatment interruptions. Antiviral therapy, 2004, Volume: 9, Issue:1 Topics: Anti-HIV Agents; CD4-Positive T-Lymphocytes; Didanosine; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; HIV-1; Humans; Hydroxyurea; Indinavir; Italy; RNA, Viral; Stavudine; Time Factors; Viral Load; Viremia	2004
Incidence of pancreatitis in HIV-1-infected individuals enrolled in 20 adult AIDS clinical trials group studies: lessons learned. Journal of acquired immune deficiency syndromes (1999), 2005, Jun-01, Volume: 39, Issue:2 Topics: Acquired Immunodeficiency Syndrome; Didanosine; Drug Therapy, Combination; HIV-1; Humans; Hydroxyurea; Incidence; Indinavir; National Institutes of Health (U.S.); Pancreatitis; Reverse Transcriptase Inhibitors; Stavudine; United States	2005

Other Studies

15 other study(ies) available for hydroxyurea and indinavir sulfate

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
HIV-1 suppression by early treatment with hydroxyurea, didanosine, and a protease inhibitor. Lancet (London, England), 1998, Jul-18, Volume: 352, Issue:9123 Topics: Adult; Anti-HIV Agents; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Hydroxyurea; Indinavir; Male	1998
Reduction in CD8+ cell noncytotoxic anti-HIV activity in individuals receiving highly active antiretroviral therapy during primary infection. Proceedings of the National Academy of Sciences of the United States of America, 2001, Jan-16, Volume: 98, Issue:2 Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Depression, Chemical; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Hydroxyurea; Immunity, Cellular; Indinavir; Lamivudine; Lymphocyte Count; Male; Middle Aged; Nelfinavir; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Treatment Refusal; Viral Load; Viremia; Zidovudine	2001
A Lisbon traviata. Are clinicians ready to sing addio to monotherapy and libiamo to combinations? Journal of the International Association of Physicians in AIDS Care, 1995, Volume: 1, Issue:8 Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; HIV; HIV Infections; Humans; Hydroxyurea; Indinavir; Interleukin-2; Lamivudine; Mutation; Pyridines; RNA, Viral; Zalcitabine; Zidovudine	1995
Hydroxyurea - new observations. Project Inform perspective, 1998, Issue:24 Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Hydroxyurea; Indinavir; Nucleic Acid Synthesis Inhibitors; Stavudine; Viral Load; Virus Replication	1998
Extended warning on Didanosine-related pancreatitis. Research initiative, treatment action : RITA, 1999, Volume: 5, Issue:5 Topics: Anti-HIV Agents; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Hydroxyurea; Indinavir; Nucleic Acid Synthesis Inhibitors; Pancreatitis; Stavudine	1999
Complementary antiviral efficacy of hydroxyurea and protease inhibitors in human immunodeficiency virus-infected dendritic cells and lymphocytes. Journal of virology, 2002, Volume: 76, Issue:5 Topics: Cells, Cultured; Dendritic Cells; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Hydroxyurea; Indinavir; Lymphocyte Activation; Ritonavir; T-Lymphocytes	2002
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010