hydroxyurea has been researched along with guanazole in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (62.50) | 18.7374 |
| 1990's | 4 (25.00) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Hansch, C; Khwaja, TA; Selassie, CD | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Atkins, LM; Gale, GR; Meischen, SJ; Schwartz, P | 1 |
| Lewis, WH; Wright, JA | 1 |
| McClarty, G; Tipples, G | 1 |
| Romagna, F; Suter, W | 1 |
| Snapka, RM; Wani, MA | 1 |
| Spector, T | 1 |
| Hurlbert, RB; Moore, EC | 1 |
| Bacon, PE; Cory, JG; Sato, A | 1 |
| Cory, JG; Lasater, L; Sato, A | 2 |
| Hards, RG; Wright, JA | 1 |
| Dick, JE; Hards, RG; Wright, JA | 1 |
| Larsen, IK; Sjöberg, BM; Thelander, L | 1 |
| Alyahya, MY; Bhadra, S; Khan, S; Samuel, RE; Xu, YJ | 1 |
1 review(s) available for hydroxyurea and guanazole
| Article | Year |
|---|---|
The inhibition of ribonucleoside diphosphate reductase by hydroxyurea, guanazole and pyrazoloimidazole (IMPY).
Topics: Abnormalities, Drug-Induced; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Cell Survival; Cells, Cultured; DNA; DNA Repair; DNA Replication; Drug Resistance; Guanazole; Histones; Humans; Hydroxyurea; In Vitro Techniques; Mutagens; Pyrazoles; Ribonucleoside Diphosphate Reductase; Ribonucleotide Reductases; Structure-Activity Relationship; Triazoles | 1985 |
15 other study(ies) available for hydroxyurea and guanazole
| Article | Year |
|---|---|
Structure-activity relationships of antineoplastic agents in multidrug resistance.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured | 1990 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Schedule-dependency assessments of ribonucleoside diphosphate reductase inhibitors when used in combination with platinum compounds plus cyclophosphamide in the treatment of advanced L1210 leukemia.
Topics: Animals; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combination; Guanazole; Hydroxyurea; Isoquinolines; Leukemia L1210; Mice; Platinum; Ribonucleoside Diphosphate Reductase; Ribonucleotide Reductases; Thiosemicarbazones | 1979 |
Ribonucleotide reductase from wild type and hydroxyurea-resistant chinese hamster ovary cells.
Topics: Animals; Cell Line; Cell-Free System; Cells, Cultured; Cricetinae; Drug Resistance, Microbial; Guanazole; Hybrid Cells; Hydroxyurea; Mutation; Ribonucleoside Diphosphate Reductase; Ribonucleotide Reductases | 1978 |
Isolation and initial characterization of a series of Chlamydia trachomatis isolates selected for hydroxyurea resistance by a stepwise procedure.
Topics: Adenine; Animals; Chlamydia trachomatis; Cytidine Diphosphate; DNA, Bacterial; Drug Resistance, Microbial; Guanazole; Hydroxyurea; L Cells; Mutation; Ribonucleotide Reductases; Selection, Genetic | 1991 |
DNA repair induced by various mutagens in rat hepatocyte primary cultures measured in the presence of hydroxyurea, guanazole or aphidicolin.
Topics: Animals; Aphidicolin; Cells, Cultured; Diterpenes; DNA Damage; DNA Repair; Guanazole; Hydroxyurea; Liver; Male; Mutagenicity Tests; Mutagens; Rats; Rats, Inbred Strains; Salmonella typhimurium; Triazoles; Ultraviolet Rays | 1990 |
Drug-induced loss of unstably amplified genes.
Topics: Camptothecin; Dose-Response Relationship, Drug; Drug Resistance; Eflornithine; Gene Amplification; Guanazole; Hydroxyurea; Methotrexate; Proflavine; Tetrahydrofolate Dehydrogenase | 1990 |
Inhibition of ribonucleotide reductases encoded by herpes simplex viruses.
Topics: Acyclovir; Antiviral Agents; Guanazole; Herpes Simplex; Humans; Hydroxyurea; Nucleotides; Pyridoxal Phosphate; Ribonucleotide Reductases; Simplexvirus | 1985 |
Studies on the differential mechanisms of inhibition of ribonucleotide reductase by specific inhibitors of the non-heme iron subunit.
Topics: Anaerobiosis; Animals; Catalase; Cell Division; Cells, Cultured; Deferoxamine; Guanazole; Humans; Hydroxyurea; Isoenzymes; Isoquinolines; Leukemia L1210; Peroxidase; Peroxidases; Pyrazoles; Quinolines; Ribonucleoside Diphosphate Reductase; Ribonucleotide Reductases; Triazoles | 1984 |
Effect of iron-chelating agents on inhibitors of ribonucleotide reductase.
Topics: Animals; Carcinoma, Ehrlich Tumor; Chelating Agents; Deferoxamine; Edetic Acid; Female; Guanazole; Hydroxyurea; Iron Chelating Agents; Mice; Mice, Inbred ICR; Oxyquinoline; Ribonucleotide Reductases | 1981 |
N-carbamoyloxyurea-resistant Chinese hamster ovary cells with elevated levels of ribonucleotide reductase activity.
Topics: Animals; Cells, Cultured; Cricetinae; Cricetulus; Deoxyadenine Nucleotides; Drug Resistance; Female; Guanazole; Hydroxyurea; Kinetics; Ovary; Ribonucleotide Reductases; Substrate Specificity | 1981 |
Studies of mammalian ribonucleotide reductase activity in intact permeabilized cells: a genetic approach.
Topics: Animals; Cell Line; Cell Membrane Permeability; Cricetinae; Cricetulus; Drug Resistance; Guanazole; Humans; Hydroxyurea; Kinetics; L Cells; Mice; Mutation; Ribonucleotide Reductases | 1980 |
Specific inhibition of the subunits of ribonucleotide reductase as a new approach to combination chemotherapy.
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Drug Interactions; Drug Synergism; Female; Guanazole; Hydroxyurea; Iron Chelating Agents; Isoquinolines; Mice; Pyrazoles; Ribonucleoside Diphosphate Reductase; Ribonucleotide Reductases; Thiosemicarbazones | 1980 |
Characterization of the active site of ribonucleotide reductase of Escherichia coli, bacteriophage T4 and mammalian cells by inhibition studies with hydroxyurea analogues.
Topics: Animals; Binding Sites; Cattle; Chemical Phenomena; Chemistry; Escherichia coli; Fibroblasts; Guanazole; Hydroxyurea; In Vitro Techniques; Mice; Nitroso Compounds; Ribonucleotide Reductases; Structure-Activity Relationship; T-Phages; Thymus Gland | 1982 |
Replication stress induced by the ribonucleotide reductase inhibitor guanazole, triapine and gemcitabine in fission yeast.
Topics: Cell Cycle Proteins; Checkpoint Kinase 2; Deoxycytidine; DNA Replication; Enzyme Inhibitors; Gemcitabine; Guanazole; Humans; Hydroxyurea; Pyridines; Ribonucleotide Reductases; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Thiosemicarbazones | 2022 |