hydroxyurea has been researched along with givinostat in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Amaru Calzada, A; Finazzi, G; Golay, J; Introna, M; Leoni, F; Mascagni, P; Pedrini, O; Rambaldi, A | 1 |
| Barbui, T; Barosi, G; Cilloni, D; Demuth, T; Finazzi, G; Finazzi, MC; Fioritoni, G; Martinelli, V; Musolino, C; Nobile, F; Olimpieri, OM; Pogliani, EM; Rambaldi, A; Ruggeri, M; Sivera, P; Specchia, G; Tollo, SD; Vannucchi, AM | 1 |
| Cappellini, MD; Fossati, G; Modena, D; Porretti, L; Ronzoni, L; Sonzogni, L; Trombetta, E | 1 |
| Miyamoto, T; Yoshimoto, G | 1 |
| Bose, P; Chifotides, HT; Verstovsek, S | 1 |
2 review(s) available for hydroxyurea and givinostat
| Article | Year |
|---|---|
[Treatment strategy for myeloproliferative neoplasms].
Topics: Adrenal Cortex Hormones; Aspirin; Calreticulin; Carbamates; Clinical Trials as Topic; Drug Therapy, Combination; Hematopoietic Stem Cell Transplantation; Humans; Hydroxyurea; Immunosuppressive Agents; Janus Kinase 2; Molecular Targeted Therapy; Mutation; Nitriles; Platelet Aggregation Inhibitors; Polycythemia Vera; Primary Myelofibrosis; Prognosis; Pyrazoles; Pyrimidines; Quinazolines; Receptors, Thrombopoietin; Thalidomide; Thrombocythemia, Essential | 2014 |
Givinostat: an emerging treatment for polycythemia vera.
Topics: Animals; Carbamates; Disease Progression; Histone Deacetylase Inhibitors; Humans; Hydroxyurea; Janus Kinase 2; Mutation; Polycythemia Vera | 2020 |
1 trial(s) available for hydroxyurea and givinostat
| Article | Year |
|---|---|
A phase II study of Givinostat in combination with hydroxycarbamide in patients with polycythaemia vera unresponsive to hydroxycarbamide monotherapy.
Topics: Adult; Aged; Aged, 80 and over; Carbamates; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Histone Deacetylase Inhibitors; Humans; Hydroxyurea; Male; Middle Aged; Nucleic Acid Synthesis Inhibitors; Polycythemia Vera; Treatment Failure; Treatment Outcome | 2013 |
3 other study(ies) available for hydroxyurea and givinostat
| Article | Year |
|---|---|
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Givinostat and hydroxyurea synergize in vitro to induce apoptosis of cells from JAK2(V617F) myeloproliferative neoplasm patients.
Topics: Amino Acid Substitution; Antineoplastic Agents; Apoptosis; Blotting, Western; Carbamates; Caspase 3; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Drug Synergism; Humans; Hydroxyurea; Janus Kinase 2; Leukocytes, Mononuclear; Mutation; Myeloproliferative Disorders; Polycythemia Vera | 2013 |
Modulation of gamma globin genes expression by histone deacetylase inhibitors: an in vitro study.
Topics: Adult; Anemia, Sickle Cell; Antigens, CD34; Butyric Acid; Carbamates; Cell Differentiation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Erythroid Precursor Cells; Erythropoiesis; gamma-Globins; Gene Expression Regulation; Hemoglobins; Histone Deacetylase Inhibitors; Humans; Hydroxyurea | 2014 |