hydroxyurea has been researched along with dactinomycin in 215 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 189 (87.91) | 18.7374 |
| 1990's | 12 (5.58) | 18.2507 |
| 2000's | 7 (3.26) | 29.6817 |
| 2010's | 7 (3.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hansch, C; Khwaja, TA; Selassie, CD | 1 |
| Dias, CB; Hansch, C; Khwaja, TA; Pentecost, S; Selassie, CD | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Margolis, LW; Phillips, TL; Wharam, MD | 1 |
| Borsos, T; Ohanian, SH; Segerling, M | 2 |
| Cihak, A | 1 |
| Davies, J; Schindler, D | 1 |
| Laudien, H | 1 |
| Rice, M; Stringer, J; Swanstrom, R; Wagner, EK | 1 |
| Buell, DN; Ebert, PS; Wars, I | 1 |
| Ross, DW | 1 |
| Akabayashi, T; Ito, H; Kurihara, S; Tobe, T; Tsutsui, F | 1 |
| Dubbs, DR; Kit, S | 1 |
| Kimler, BF; Leeper, DB; Schneiderman, MH | 1 |
| Honjo, T; Mizuno, D; Natori, S; Shimizu, A; Tsuda, M | 1 |
| Lotem, J; Sachs, L | 2 |
| Becker, Y | 1 |
| Bhuyan, BK; Day, KJ; Fraser, TJ | 1 |
| Esteban, M; Holowczak, JA | 1 |
| Aaronson, SA; Greenberger, JS | 1 |
| Thacore, HR; Youngner, JS | 2 |
| Parks, WP; Scolnick, EM; Young, HA | 1 |
| Alford, BL; Barnes, EM | 1 |
| Hammond, CB; Schmidt, HJ; Suciu, TN; Surwit, EA | 1 |
| Raghavan, V | 1 |
| Bienkowski, M; Dunn, JR; Honn, KV; Marnett, LJ; Morgan, LR | 1 |
| Aubertin, AM; Fellinger, E; Kirn, A; Travo, C | 1 |
| Kreja, L; Seidel, HJ; Steinheider, G | 1 |
| Ellem, KA; Mironescu, S | 1 |
| Gordon, A; Segal, J | 1 |
| Mironescu, S | 1 |
| Blümel, G; Osterkamp, U; Stavrou, D; Wriedt-Lübbe, I; Zänker, KS | 1 |
| Frankfurt, OS | 2 |
| Bishop, J; Hallinan, FM; Lee, SH; Rozee, KR | 1 |
| Klem, EB | 1 |
| Hittelman, WN; Rao, PN | 1 |
| Kleckow, M; Mattern, J; Vogt-Moykopf, I; Volm, M; Wayss, K | 1 |
| Andoh, T; Kitagawa, T | 1 |
| Gotlib, VIa; Khvylia, LA; Pelevina, II | 1 |
| Block, NL; Camuzzi, F; Claflin, A; Politano, VA; Stover, B; Troner, M | 1 |
| Hunter, JA | 1 |
| Bases, R; Hsu, KC; Liebeskind, D; Mendez, F; Neubort, S | 1 |
| Philips, FS; Sternberg, SS | 1 |
| Gracy, RW; Jacobson, EL; Kester, MV | 1 |
| Koga, M; Umeda, T | 1 |
| Green, CD; Tata, JR | 1 |
| Szolgay, E; Tálas, M | 1 |
| Boyse, EA; Goldstein, G; Hammerling, U; Storrie, B | 1 |
| Kaufmann, M; Mattern, J; Volm, M; Wayss, K | 1 |
| Tokumaru, T; Wilentz, J | 1 |
| Stevens, J; Stevens, YW | 1 |
| Benedict, WF; Karon, M; Rucker, N | 1 |
| Brachet, J; Tencer, R; Tondeur-Six, N | 1 |
| Blaschko, WJ; Drew, CM; Howell, SH | 1 |
| Berliner, JA; Gerschenson, LE | 1 |
| Luce, JK | 1 |
| Berger, NA; Johnson, ES | 1 |
| Burchenal, JH; D'Angio, G; Exelby, P; Lieberman, PH; Murphy, ML; Wollner, N | 1 |
| Baril, EF; Davis, PB; Laszlo, J | 1 |
| Cocks, BG; Hamilton, JA; Vairo, G | 1 |
| Carter, GL; Cory, JG | 1 |
| Fujishima, M; Kosaka, C; Masuda, J; Ogata, J; Sasaguri, T; Shimokado, K; Yokota, T | 1 |
| Fabian, I; Golde, DW; Savion, N; Waksman, Y | 1 |
| Alexander, RB; Coffey, DS; Nelson, WG | 1 |
| Ducommun, B; Wright, M | 1 |
| Blessing, JA; Curry, SL; DiSaia, PJ; Soper, JT; Twiggs, LB | 1 |
| Gottlieb, M; Mackow, MC; Neubert, TA | 1 |
| Bolis, G; Bonazzi, C; Landoni, F; Mangili, G; Mangioni, C; Vergadoro, F; Zanaboni, F | 1 |
| Itoh, T; Kasahara, S | 1 |
| Bantle, JA; Courchesne, CL | 1 |
| Choo, YC; Ma, HK; Wong, LC | 1 |
| Jones, PA; Liu, L; Nyce, J | 1 |
| Ernst, DN; Hobbs, MV; McQuitty, DN; Weigle, WO | 1 |
| Amato, DA; Ash, A; Borden, EC; Bruckner, H; Creech, RH; Cunningham, TJ; Falkson, G; Guerry, D; Savlov, ED | 1 |
| Bantle, JA; Courchesne, CL; Dawson, DA | 1 |
| Kreja, L; Seidel, HJ | 1 |
| Krieger, NS; Stathopoulos, VM; Stern, PH | 1 |
| Dewey, WC; Gray, JW; Rice, GC | 1 |
| Seidel, HJ | 1 |
| Brachet, J | 1 |
| Tobey, RA | 1 |
| Greenwald, ES | 1 |
| Almeyda, J; Levantine, A | 1 |
| Clarkson, BD; Yataganas, X | 1 |
| Marchetta, FC | 1 |
| Dantzig, PI | 1 |
| Bagshaw, MA; Goffinet, DR | 1 |
| Sugiura, K | 1 |
| Fievez, M; Malpoix, P; Zampetti-Bosseler, F | 1 |
| Fievez, M; Malpoix, P; Zampetti, F | 1 |
| Gelbard, AS; Kim, JH; Perez, AG | 1 |
| Watne, AL | 1 |
| Brachet, J; Hanocq, F; Van Gansen, P | 1 |
| Kuroki, T | 1 |
| Falkson, G; Geddes, EW | 1 |
| Ammermann, D; Sapra, GR | 1 |
| Andersson, J; Melchers, F | 1 |
| Cleaver, JE | 1 |
| Aasen, J; Haukenes, G | 1 |
| Smithers, DW | 1 |
| Bhuyan, BK; Fraser, TJ | 1 |
| Selawry, OS | 1 |
| Kapp, LN; Okada, S | 1 |
| Rideau, C; Smulson, ME | 1 |
| Sokol, F; Tan, KB | 1 |
| Kirk-Bell, S; Lehmann, AR; Shall, S; Whish, WJ | 1 |
| Honess, RW; Roizman, B | 1 |
| Garfinkle, B; McAuslan, BR | 1 |
| Asher, Y; Becker, Y | 1 |
| Banerjee, S; Bhattacharya, A; Datta, A | 1 |
| Meneghini, R | 1 |
| Bhattacharya, A; Datta, A; Puri, M | 1 |
| Lefebvre, JC; Lemay, P | 1 |
| Clarkson, SG | 1 |
| Granner, DK; Thompson, EB; Tomkins, GM | 1 |
| Godman, GC; Sawicki, SG | 1 |
| Breindl, M; Gallwitz, D | 1 |
| Baserga, R; Nicolini, C | 1 |
| Bello, LJ | 1 |
| Elizan, TS; Schwartz, J | 1 |
| Cunningham, DD; Remo, RA | 1 |
| Craig, N | 1 |
| Ishikawa, H; Nagayama, T; Niizuma, K | 1 |
| Band, RN; Mohrlok, S | 1 |
| Bases, R; Erlanger, B; Hsu, KC; Liebeskind, D | 1 |
| Cameron, IL; Rudick, MJ | 1 |
| Banerjee, S; Kelleher, JK; Margulis, L; Winston, M; Younger, KB | 1 |
| Barnea, A; Lindner, HR | 1 |
| Cikes, M; Klein, G | 1 |
| Concannon, JP; Hagemann, RF | 1 |
| Hershey, H; Mueller, GC; Stieber, J | 1 |
| Harris, JW; Teng, SS | 1 |
| deKernion, JB; Persky, L; Rose, D; Soloway, MS | 1 |
| Gross, PR; Ruderman, JV | 1 |
| Hellmann, K | 1 |
| Birkett, S; Salaman, DF | 1 |
| Kann, HE; Kohn, KW; Lyles, JM | 1 |
| Stutzman, L | 1 |
| Dales, S; Ichihashi, Y; Matsumoto, S | 1 |
| Bridson, WE; Kohler, PO; Rayford, PL | 1 |
| Baxby, D; Rondle, CJ | 1 |
| Pasternak, J; Samoiloff, MR | 1 |
| Dawson, KM | 1 |
| Fukuhara, M; Horikawa, M; Nikaido, O; Sugahara, T; Suzuki, F | 1 |
| Bennett, LR; Byfield, JE; Lee, YC | 1 |
| Connell, DI; DiPaolo, JA; Riechers, LA | 1 |
| Barry, JM; Green, CD; Skarda, J | 1 |
| Banks, J; Marks, PA; Terada, M | 1 |
| Sinclair, WK | 2 |
| Smets, LA | 1 |
| Arlett, CF | 1 |
| Gallwitz, D; Mueller, GC | 1 |
| Cognetti, G; Gross, PR; Hunter, AL; Kedes, LH | 1 |
| Moore, EC; Murphree, S; Stubblefield, E | 1 |
| Barry, JM; Mayne, R | 1 |
| Madoc-Jones, H; Mauro, F | 1 |
| Kanamaru, R; Kuroki, T; Sato, H | 1 |
| Elkind, MM; Kano, E | 1 |
| Brockman, RW; Lloyd, HH; Mellett, LB; Montgomery, JA; Schabel, FM; Skipper, HE; Wilkoff, LJ | 1 |
| Koyama, H; Ono, T | 1 |
| Djordjevic, B; Gelbard, AS; Kim, JH; Perez, AG | 1 |
| McGuire, WL; O'Malley, BW | 1 |
| Granoff, A; Kucera, LS | 1 |
| Eker, P | 1 |
| Brachet, J; Van Assel, S | 1 |
| Mirand, EA; Price, FW; Steeves, RA | 1 |
| Sung, SC | 1 |
| King, CD; Van Lancker, JL | 1 |
| Elkind, MM; Kano, E; Sutton-Gilbert, H | 1 |
| Barry, JM; Leader, DP | 1 |
| Hills, WJ; Rufino, C; Stehlin, JS | 1 |
| Elkind, MM; Kamper, C; Moses, WB; Sutton-Gilbert, H | 1 |
| Brunner, FF; Daum, G; Paltauf, F; Zinser, E | 1 |
| Bagshawe, KD | 1 |
| Alexandre, H; Brachet, J; de Petrocellis, B; Ficq, A | 1 |
| Barnard, DE; Clayton, LA; Currie, JL; Hammond, CB; Weed, JC | 1 |
| Gordon, SR; Rothstein, H | 1 |
| Block, NL; Claflin, AJ; Greenstein, DB; Irvin, GL; Pollack, A; Prudhomme, DL | 1 |
| Lieber, MM | 1 |
| Brewer, PP; Hellman, KB | 1 |
| Sergiescu, D | 1 |
| Al-Sarraf, M; Balcerzak, SP; Costanzi, JJ; Eyre, HJ; Fletcher, WS; Frank, J; O'Bryan, RM; Taylor, S | 1 |
| Baumbach, LL; Marashi, F; Plumb, M; Stein, G; Stein, J | 1 |
| Mathinos, PR; Randall, JL; Ritter, EJ; Scott, WJ; Wilson, JG | 1 |
| Abe, E; Hayashi, T; Miyaura, C; Shiina, Y; Suda, T; Tanaka, H | 1 |
| Cambier, JC; Monroe, JG | 1 |
| Grotendorst, G; Martin, GR; Schiffmann, E; Seppä, H; Seppä, S | 1 |
| Kimura, T; Matsumoto, Y; Yoshida, A | 1 |
| Fehér, I; Gidali, J | 1 |
| Boyde, A; Buttle, DJ; Hill, PA; Jones, SJ; Meikle, MC; Murata, M; Reynolds, JJ | 1 |
| Kietlińska, Z; Sablińska, B; Zieliński, J | 1 |
| Blankemeyer, JT; Stringer, BK | 1 |
| Gordon, D; Sarkar, R; Stanley, JC; Webb, RC | 1 |
| Angelier, N; Moreau, N; Prudhomme, C | 1 |
| Bagshawe, KD; Bower, M; Foskett, M; Holden, L; Newlands, ES; Rustin, GJ; Short, D | 1 |
| Matsui, T; Taketo, A | 1 |
| Cross, M; Erbes, M; Hansch, M; Hauschildt, S; Pfister, M; Thiele, A | 1 |
| BEATTY, EC; BRUBAKER, C; HAMMOND, D; HARTMANN, JR; ORIGENES, ML; SHORE, N; WILLIAMS, KO | 1 |
| Grosse, F; Hemmerich, P; Köhler, C; Zhang, S | 1 |
| Garriott, ML; Hoffman, WP; Lee, C; Murphy, GP; Phelps, JB | 1 |
| An, RF; Wu, TX; Xue, Y; Zhang, J | 1 |
| Belfort, P; Braga, A; Consonni, M; Delmanto, LR; Maestá, I; Michelin, OC; Rudge, MV | 1 |
| Deng, L; Wu, T; Yan, X; Zhang, J | 1 |
| Vigneron, AM; Vousden, KH | 1 |
| Deng, L; Lawrie, TA; Wu, T; Zhang, J | 1 |
| Chan, KK; Chu, MM; Ma, Y; Ngan, HY; Tse, KY | 1 |
16 review(s) available for hydroxyurea and dactinomycin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Inhibitors of macromolecular synthesis in yeast.
Topics: Acriflavine; Amphotericin B; Anisomycin; Anti-Bacterial Agents; Antineoplastic Agents; Cycloheximide; Dactinomycin; Daunorubicin; Deoxyadenosines; Depression, Chemical; DNA; Ethidium; Fluorouracil; Fungal Proteins; Hydroxyurea; Mitomycins; Nalidixic Acid; Phenazines; Phenylethyl Alcohol; Porfiromycin; Puromycin; RNA; Saccharomyces cerevisiae; Streptonigrin; Sulfanilamides; Triaziquone; Trichothecenes; Uracil | 1975 |
Trends in research and development of antiviral substances.
Topics: Amanitins; Amantadine; Amino Acids; Antiviral Agents; Benzimidazoles; Camptothecin; Chemical Phenomena; Chemistry; Cystamine; Dactinomycin; Distamycins; DNA-Directed RNA Polymerases; Hydroxyurea; Interferon Inducers; Interferons; Methisazone; Nucleosides; Plicamycin; Polysaccharides; Research Design; Rhodanine; Rifamycins; Selenium; Silicon; Tungsten; Viruses; Zinc | 1975 |
Cutaneous malignant melanoma.
Topics: Adult; Aged; Biopsy; Carmustine; Cyclophosphamide; Dactinomycin; Female; Humans; Hydroxyurea; Male; Melanoma; Melphalan; Microscopy, Electron; Middle Aged; Prognosis; Skin Neoplasms; Sunlight; Wounds and Injuries | 1976 |
Cancer chemotherapy. II.
Topics: Animals; Antineoplastic Agents; Asparaginase; Azathioprine; Bleomycin; Cytarabine; Dactinomycin; Daunorubicin; Dimethylamines; Doxorubicin; Floxuridine; Fluorouracil; Humans; Hydroxyurea; Imidazoles; Mercaptopurine; Mitomycins; Mitotane; Neoplasms; Nitrosourea Compounds; Pipobroman; Procarbazine; Streptonigrin; Streptozocin; Thioguanine; Triazenes; Triazines; Vinblastine; Vincristine | 1972 |
Drug reactions. XXIV. Cutaneous reactions to cytostatic agents.
Topics: Alopecia; Aminopterin; Antineoplastic Agents; Asparaginase; Azathioprine; Bleomycin; Busulfan; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug Eruptions; Erythema; Fluorouracil; Gynecomastia; Humans; Hydroxyurea; Methotrexate; Photosensitivity Disorders; Pigmentation Disorders; Radiation Injuries; Stomatitis; Vinblastine | 1974 |
Immunosuppressive and cytotoxic drugs in dermatology.
Topics: Animals; Antineoplastic Agents; Azathioprine; Azauridine; Bleomycin; Chlorambucil; Cyclophosphamide; Cytarabine; Dactinomycin; Humans; Hydroxyurea; Immunosuppressive Agents; Mercaptopurine; Methotrexate; Procarbazine; Skin Diseases; Skin Neoplasms; Vinblastine; Vincristine | 1974 |
Clinical use of radiation sensitizing agents.
Topics: Animals; Antimetabolites, Antineoplastic; Bleomycin; Bromodeoxycytidine; Bromodeoxyuridine; Bromouracil; Carcinoma, Squamous Cell; Dactinomycin; Dose-Response Relationship, Radiation; Floxuridine; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Idoxuridine; Neoplasms; Neoplasms, Experimental; Radiation-Sensitizing Agents | 1974 |
Solid tumor chemotherapy: What have we to offer.
Topics: Adult; Antineoplastic Agents; Child; Cyclophosphamide; Dactinomycin; Floxuridine; Fluorouracil; Humans; Hydroxyurea; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Palliative Care; Thiotepa; Time Factors; Vincristine | 1970 |
[Chemical carcinogenesis in vitro. 2].
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Culture Techniques; Dactinomycin; DNA; Genes; HeLa Cells; Hydroxyurea; Mutation; Neoplasms, Experimental; Niacinamide; Puromycin; Quinolines; RNA; Transformation, Genetic | 1970 |
Proliferation and maturation of bone marrow-derived lymphocytes.
Topics: Animals; Antibody-Producing Cells; B-Lymphocytes; Binding Sites, Antibody; Carbohydrates; Cell Division; Cell Separation; Cells, Cultured; Centrifugation; Dactinomycin; Hydroxyurea; Immunoglobulin Fab Fragments; Immunoglobulin Heavy Chains; Immunoglobulin M; Iodine Radioisotopes; Leucine; Lipopolysaccharides; Mice; RNA, Messenger; Spleen; Thymidine; Thymus Gland; Time Factors; Tritium | 1974 |
Monochemotherapy of bronchogenic carcinoma withs special reference to cell type.
Topics: Adenocarcinoma; Alkylating Agents; Antineoplastic Agents; Carcinoma, Bronchogenic; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Floxuridine; Humans; Hydroxyurea; Lung Neoplasms; Mechlorethamine; Methotrexate; Mitomycins; Nitrosourea Compounds; Plicamycin; Porfiromycin; Procarbazine; Streptonigrin; Thiotepa; Vinblastine | 1973 |
Treatment of high-risk choriocarcinoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Choriocarcinoma; Chorionic Gonadotropin; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; Hydroxyurea; Neoplasm Metastasis; Pregnancy; Prognosis; Risk; Trophoblastic Neoplasms; Uterine Hemorrhage; Uterine Neoplasms; Vincristine | 1984 |
Combination chemotherapy for high-risk gestational trophoblastic tumour.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Hydroxyurea; Leucovorin; Methotrexate; Pregnancy; Trophoblastic Tumor, Placental Site; Vincristine | 2006 |
Combination chemotherapy for high-risk gestational trophoblastic tumour.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Hydroxyurea; Melphalan; Methotrexate; Pregnancy; Trophoblastic Tumor, Placental Site; Vincristine | 2009 |
Combination chemotherapy for primary treatment of high-risk gestational trophoblastic tumour.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dactinomycin; Doxorubicin; Early Termination of Clinical Trials; Female; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Hydroxyurea; Leucovorin; Melphalan; Methotrexate; Pregnancy; Trophoblastic Tumor, Placental Site; Vincristine | 2013 |
3 trial(s) available for hydroxyurea and dactinomycin
| Article | Year |
|---|---|
A prospective randomized comparison of methotrexate, dactinomycin, and chlorambucil versus methotrexate, dactinomycin, cyclophosphamide, doxorubicin, melphalan, hydroxyurea, and vincristine in "poor prognosis" metastatic gestational trophoblastic disease:
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; Hydroxyurea; Leucovorin; Methotrexate; Multicenter Studies as Topic; Pregnancy; Prospective Studies; Random Allocation; Trophoblastic Neoplasms; Uterine Neoplasms; Vincristine | 1989 |
Combined radiotherapy and chemotherapy of lymphomas and other cancers.
Topics: Clinical Trials as Topic; Cyclophosphamide; Dactinomycin; Fluorouracil; Follow-Up Studies; Hematopoietic System; Hodgkin Disease; Humans; Hydroxyurea; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Methotrexate; Placebos; Vincristine | 1971 |
Combination chemotherapy plus levamisole in the treatment of disseminated malignant melanoma. A Southwest Oncology Group study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Clinical Trials as Topic; Dacarbazine; Dactinomycin; Humans; Hydroxyurea; Levamisole; Melanoma; Random Allocation; Skin Neoplasms | 1984 |
196 other study(ies) available for hydroxyurea and dactinomycin
| Article | Year |
|---|---|
Structure-activity relationships of antineoplastic agents in multidrug resistance.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured | 1990 |
Comparative structure-activity relationships of antifolate triazines inhibiting murine tumor cells sensitive and resistant to methotrexate.
Topics: Animals; Chemical Phenomena; Chemistry, Physical; Chickens; Drug Resistance; Folic Acid Antagonists; Humans; Leukemia L5178; Leukemia, Experimental; Mathematics; Methotrexate; Mice; Structure-Activity Relationship; Triazines | 1984 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Modification of radiation injury to normal tissues by chemotherapeutic agents.
Topics: Animals; Antineoplastic Agents; Bleomycin; Carmustine; Cyclophosphamide; Dactinomycin; Dose-Response Relationship, Radiation; Doxorubicin; Esophagus; Hydroxyurea; Intestines; Lung; Male; Mice; Prednisolone; Radiation Injuries; Radiation-Protective Agents; Vincristine | 1975 |
Enhancing effect by metabolic inhibitors on the killing of tumor cells by antibody and complement.
Topics: Animals; Antibodies, Neoplasm; Antigen-Antibody Reactions; Antineoplastic Agents; Azacitidine; Carcinoma, Hepatocellular; Cells, Cultured; Complement System Proteins; Cyclophosphamide; Cytarabine; Dactinomycin; Doxorubicin; Fluorouracil; Guinea Pigs; Hydroxyurea; Liver Neoplasms; Mercaptopurine; Methotrexate; Mitomycins; Neoplasms, Experimental; Puromycin; Vincristine | 1975 |
Character of the stimulatory response of uridine kinase in rat livers to cycloheximide treatment.
Topics: Animals; Azacitidine; Cycloheximide; Cytarabine; Dactinomycin; Enzyme Activation; Hydroxyurea; Kinetics; Liver; Male; Mitomycins; Phosphotransferases; Puromycin; Rats; Starvation; Uridine Kinase | 1975 |
[On the effect of some inhibitors of proteinbiosynthesis on activity and learning behavior of goldfish (Carassius auratus auratus L)].
Topics: Animals; Azauridine; Behavior, Animal; Chromomycins; Cycloheximide; Cyprinidae; Dactinomycin; DNA; Goldfish; Hydroxyurea; Memory; Nerve Tissue Proteins; Puromycin; Quinolines; RNA | 1975 |
The association of the infecting DNA of herpes simplex virus with cellular components.
Topics: Cell Nucleus; Cycloheximide; Dactinomycin; DNA Replication; DNA, Viral; HeLa Cells; Hydroxyurea; Neoplasm Proteins; Phenols; Pronase; Simplexvirus; Transcription, Genetic | 1976 |
Erythroid differentiation in cultured Friend leukemia cells treated with metabolic inhibitors.
Topics: 5-Aminolevulinate Synthetase; Antimetabolites; Cell Differentiation; Cell Line; Clone Cells; Cycloheximide; Dactinomycin; Dimethyl Sulfoxide; DNA, Neoplasm; Hemoglobins; Hydroxyurea; Leukemia; Neoplasm Proteins; Plicamycin; Protein Biosynthesis; RNA; RNA-Directed DNA Polymerase; RNA, Neoplasm | 1976 |
Cell volume growth after cell cycle block with chemotherapeutic agents.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Bleomycin; Cell Division; Cell Line; Cells, Cultured; Colchicine; Cycloheximide; Cytarabine; Dactinomycin; Dose-Response Relationship, Drug; Hydroxyurea; Kinetics; Puromycin; Thymidine; Vinblastine | 1976 |
Serum antibodies to herpesvirus early antigens in patients with cervical carcinoma determined by anticomplement immunofluorescence technique.
Topics: Antibodies, Viral; Antigens, Viral; Cells, Cultured; Complement Fixation Tests; Culture Media; Cycloheximide; Dactinomycin; Epitopes; Female; Fluorescent Antibody Technique; Humans; Hydroxyurea; Simplexvirus; Uterine Cervical Neoplasms | 1976 |
Regulation of herpesvirus thymidine kinase activity in LM(TK) cells transformed by ultraviolet light-irradiated herpes simplex virus.
Topics: Cell Line; Cell Transformation, Neoplastic; Clone Cells; Cycloheximide; Cytarabine; Dactinomycin; Deoxyadenosines; Enzyme Induction; Epitopes; Herpesviridae; Hydroxyurea; Simplexvirus; Thymidine Kinase; Ultraviolet Rays; Vaccinia virus | 1977 |
Induction of concentration-dependent blockade in the G2 phase of the cell cycle by cancer chemotherapeutic agents.
Topics: Antineoplastic Agents; Bleomycin; Cell Cycle; Cells, Cultured; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Doxorubicin; Hydroxyurea; Lucanthone; Mitomycins; Puromycin | 1978 |
Induced synthesis of immunoglobulin messenger RNA accompanies induction of immunoglobulin production in cultured mouse spleen cells.
Topics: Animals; Cycloheximide; Cytarabine; Dactinomycin; DNA; Escherichia coli; Globins; Hydroxyurea; Immunoglobulin kappa-Chains; Immunoglobulin Light Chains; Lipopolysaccharides; Male; Mice; RNA, Messenger; Spleen; Uridine | 1978 |
Control of normal differentiation of myeloid leukemic cells. VI. Inhibition of cell multiplication and the formation of macrophages.
Topics: Animals; Blood; Bromodeoxyuridine; Cell Adhesion; Cell Differentiation; Cell Division; Cell Movement; Clone Cells; Cycloheximide; Cytarabine; Dactinomycin; Endotoxins; Floxuridine; Hydroxyurea; Idoxuridine; Leukemia, Myeloid; Macrophages; Mice; Mitomycins; Thymidine; Vinblastine | 1975 |
Cell proliferation kinetics and drug sensitivity of exponential and stationary populations of cultured L1210 cells.
Topics: Amino Acids; Animals; Antineoplastic Agents; Carmustine; Cell Division; Cell Survival; Cells, Cultured; Culture Media; Cytarabine; Dactinomycin; Daunorubicin; DNA, Neoplasm; Doxorubicin; Glucose; Hydroxyurea; Kinetics; Leukemia L1210; Lomustine; Streptozocin; Thymidine; Vincristine | 1977 |
Replication of vaccinia DNA in mouse L cells. II. In vitro DNA synthesis in cytoplasmic extracts.
Topics: Cytoplasm; Dactinomycin; DNA-Directed DNA Polymerase; DNA, Viral; Floxuridine; Hydroxyurea; Kinetics; L Cells; Nucleic Acid Conformation; Uracil Nucleotides; Vaccinia virus | 1977 |
Cycloheximide induction of xenotropic type C virus from synchronized mouse cells: metabolic requirements for virus activation.
Topics: Animals; Cell Division; Cell Line; Cycloheximide; Cytarabine; Dactinomycin; DNA, Neoplasm; Hydroxyurea; Idoxuridine; Mice; Mice, Inbred Strains; Mitomycins; Retroviridae; RNA, Neoplasm; Sarcoma, Experimental; Virus Replication | 1975 |
Abortive infection of a rabbit cornea cell line by vesicular stomatitis virus: conversion to productive infection by superinfection with vaccinia virus.
Topics: Animals; Cell Line; Centrifugation, Density Gradient; Cornea; Cycloheximide; Dactinomycin; DNA-Directed RNA Polymerases; Hydroxyurea; L Cells; Rabbits; RNA, Viral; Tritium; Uridine; Vaccinia virus; Vesicular stomatitis Indiana virus; Virus Replication | 1975 |
Biochemical and physiological mechanisms in glucocorticoid hormone induction of mouse mammary tumor virus.
Topics: Antigens, Viral; Clone Cells; Cycloheximide; Cytarabine; Dactinomycin; Dexamethasone; DNA; DNA-Directed RNA Polymerases; DNA, Viral; Hydroxyurea; Kinetics; Mammary Tumor Virus, Mouse; Nucleic Acid Hybridization; Proteins; Receptors, Drug; RNA, Viral; Viral Proteins; Virus Replication | 1976 |
Regulation of hypoxanthine transport by cyclic nucleotides in cultured Chinese hamster lung fibroblasts.
Topics: Bucladesine; Cells, Cultured; Cyclic GMP; Cycloheximide; Dactinomycin; DNA; Fibroblasts; Glucagon; Hydroxyurea; Hypoxanthines; Insulin; Nucleotides, Cyclic; Theophylline; Thymidine; Xanthines | 1977 |
A new combination chemotherapy for resistant trophoblastic disease.
Topics: Adult; Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Drug Resistance; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Leucovorin; Melphalan; Methotrexate; Pregnancy; Trophoblastic Neoplasms; Uterine Neoplasms; Vincristine | 1979 |
Gibberellic acid-induced germination of spores of Anemia phyllitidis: autoradiographic study of the timing and regulation of nucleic acid and protein synthesis in relation to cell morphogenesis.
Topics: Autoradiography; Cycloheximide; Dactinomycin; Deoxyadenosines; DNA; Fluorouracil; Gibberellins; Hydroxyurea; Plant Development; Plant Proteins; RNA; Spores | 1977 |
Inhibition of DNA synthesis in Harding-Passey melanoma cells by prostaglandins A1 and A2: comparison with chemotherapeutic agents.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Dactinomycin; DNA Replication; DNA, Neoplasm; Doxorubicin; Fluorouracil; Hydroxyurea; Kinetics; Melanoma; Mice; Neoplasms, Experimental; Prostaglandins A | 1979 |
DNA damage: a consequence of the combined effect of virus infection and incorporated radioactive thymidine.
Topics: Cell Line; Cell Transformation, Viral; Cycloheximide; Dactinomycin; DNA; DNA Repair; DNA, Viral; Humans; Hydroxyurea; Iridoviridae; Thymidine | 1979 |
Characterization of a Friend virus-replicating target cell.
Topics: Animals; Blood Transfusion; Bone Marrow Cells; Cell Transformation, Viral; Colony-Forming Units Assay; Dactinomycin; Erythropoiesis; Friend murine leukemia virus; Hemorrhage; Hydroxyurea; Leukemia, Experimental; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Spleen | 1979 |
Secondary activities of diverse inhibitors potentiate the response of hamster embryo cultures to a mitotic stimulus.
Topics: Animals; Blood; Cattle; Cell Line; Cricetinae; Culture Media; Cycloheximide; Cytarabine; Dactinomycin; DNA; Epithelial Cells; Epithelium; Fibroblasts; Hydroxyurea; Mesocricetus; Mitosis; Mitotic Index; Stimulation, Chemical; Time Factors | 1977 |
The effects of actinomycin D, puromycin, cycloheximide and hydroxyurea on 3',5,3-triiodo-L-thyronine stimulated 2-deoxy-D-glucose uptake in chick embryo heart cells in vitro.
Topics: Animals; Cells, Cultured; Chick Embryo; Cycloheximide; Dactinomycin; Deoxy Sugars; Deoxyglucose; Heart; Hydroxyurea; Leucine; Myocardium; Protein Biosynthesis; Puromycin; Time Factors; Transcription, Genetic; Triiodothyronine; Uridine | 1977 |
Hyperosmotic injury in mammalian cells. Survival of CHO cells in unprotected and DMSO-treated cultures.
Topics: Animals; Cell Line; Cell Membrane; Cell Survival; Cells, Cultured; Cricetinae; Cyclophosphamide; Dactinomycin; Dimethyl Sulfoxide; Female; Freezing; Humans; Hydroxyurea; Lung; Osmotic Pressure; Ovary; Saline Solution, Hypertonic | 1977 |
Fibrinolysis induced by rat glioma cells. A mitosis-triggered process?
Topics: Animals; Astrocytoma; Cell Line; Dactinomycin; Fibrin Fibrinogen Degradation Products; Fibrinolysis; Glioma; Hydroxyurea; Mitotic Index; Neoplasms, Experimental; Plasminogen Activators; Rats; S100 Proteins | 1978 |
Resistance of stomach epithelium to cytotoxic effect of antitumor drugs. Increase of sensitivity by actinomycin D.
Topics: Animals; Antineoplastic Agents; Cell Survival; Colon; Dactinomycin; DNA; Drug Resistance; Drug Synergism; Epithelial Cells; Epithelium; Female; Gastric Mucosa; Hydroxyurea; In Vitro Techniques; Intestinal Mucosa; Male | 1977 |
The characteristics of enhanced DNA synthesis in L cells treated with interferon and arginine-deprived.
Topics: Arginine; Cell Nucleus; Cytarabine; Dactinomycin; DNA; Hydroxyurea; Interferons; L Cells; Protein Biosynthesis; Puromycin; RNA | 1977 |
Effects of antipsoriasis drugs and metabolic inhibitors on the growth of epidermal cells in culture.
Topics: Animals; Anthralin; Antimetabolites; Azauridine; Cell Division; Cells, Cultured; Cycloheximide; Cytarabine; Dactinomycin; Daunorubicin; Guinea Pigs; Hydroxyurea; Methotrexate; Mycophenolic Acid; Psoriasis; Puromycin; Skin | 1978 |
Mapping G1 phase by the structural morphology of the prematurely condensed chromosomes.
Topics: Cell Cycle; Cell Fusion; Cell Line; Cell Transformation, Neoplastic; Chromosomes; Cycloheximide; Dactinomycin; Hydroxyurea; Interphase; Thymidine | 1978 |
[Resistance testing and chemotherapy results of bronchial tumours (author's transl)].
Topics: Bronchial Neoplasms; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Resistance; Fluorouracil; Humans; Hydroxyurea; Methotrexate; Prognosis; Remission, Spontaneous; Vincristine | 1978 |
Stimulation by amphotericin B of uridine transport, RNA synthesis and DNA synthesis in density-inhibited fibroblasts.
Topics: Adenosine; Amphotericin B; Biological Transport; Cell Line; Cell Survival; Contact Inhibition; Dactinomycin; DNA; Hydroxyurea; RNA; Thymidine; Uridine | 1978 |
[Ability of cells in tissue culture to recover from damage caused by chemotherapeutic drugs].
Topics: Cell Line; Cell Survival; Dactinomycin; Dose-Response Relationship, Drug; Hydroxyurea; Methylnitrosourea; Nitrosourea Compounds | 1978 |
Further experience with chemotherapy in the Dunning prostatic adenocarcinoma.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Asparaginase; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Hybridization, Genetic; Hydroxyurea; Lomustine; Male; Methotrexate; Neoplasms, Experimental; Platinum; Prostatic Neoplasms; Rats | 1978 |
Carcinogen-induced immunoreactivity to antinucleoside antibodies in HeLa cells.
Topics: Acetoxyacetylaminofluorene; Anthracenes; Antibodies, Antinuclear; Antigen-Antibody Reactions; Benzopyrenes; Carcinogens; Cycloheximide; Cytarabine; Dactinomycin; DNA, Neoplasm; Dose-Response Relationship, Drug; Fluorescent Antibody Technique; HeLa Cells; Hydroxyurea; Methylnitronitrosoguanidine; Neoplasm Proteins; Puromycin | 1976 |
Tests for tumor induction by antitumor agents.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Benz(a)Anthracenes; Carcinogens; Dactinomycin; Daunorubicin; DNA; Female; Hydroxyurea; Mammary Neoplasms, Experimental; Mice; Mice, Inbred A; Neoplasms, Experimental; Rats | 1975 |
[Decrease in the tissue-specific resistance of gastric epithelium to acute cell death following inhibition of DNA synthesis].
Topics: Animals; Cell Survival; Dactinomycin; DNA; Drug Interactions; Epithelium; Gastric Mucosa; Hydroxyurea; Mice; Organ Specificity | 1977 |
The synthesis of a labile triosephosphate isomerase isozyme in human lymphoblasts and fibroblasts.
Topics: Carbohydrate Epimerases; Dactinomycin; DNA; Female; Fibroblasts; Guanidines; Humans; Hydroxyurea; Isoenzymes; Leucine; Lymphocytes; Placenta; Pregnancy; Protein Biosynthesis; Puromycin; RNA; Triose-Phosphate Isomerase | 1977 |
Synthesis of deoxyribonucleic acid in liver cells made permeable to nucleotides.
Topics: Adenosine Triphosphate; Animals; Cell Membrane Permeability; Centrifugation, Density Gradient; Cycloheximide; Dactinomycin; Deoxyribonucleotides; DNA; DNA Replication; DNA-Directed DNA Polymerase; Hepatectomy; Hydroxyurea; Kinetics; Liver; Liver Regeneration; Magnesium; Rats; Sodium; Thymine Nucleotides; Time Factors | 1977 |
Direct induction by estradiol on vitellogenin synthesis in organ cultures of male Xenopus laevis liver.
Topics: Albumins; Animals; Cytarabine; Dactinomycin; Dose-Response Relationship, Drug; Estradiol; Hydroxyurea; Kinetics; Lipoproteins; Liver; Male; Organ Culture Techniques; Protein Biosynthesis; Vitellogenins; Xenopus | 1976 |
Interferon synthesis in mouse peritoneal cells damaged by X-irradiation.
Topics: Amino Acids; Animals; Ascitic Fluid; Cell Count; Cells, Cultured; Dactinomycin; Hydroxyurea; Interferons; Mice; Mitomycins; Newcastle disease virus; Puromycin; Thymidine; Uridine; X-Rays | 1976 |
Differentiation of thymocytes: evidence that induction of the surface phenotype requires transcription and translation.
Topics: Animals; Camptothecin; Cell Differentiation; Cycloheximide; Cytarabine; Dactinomycin; Deoxyadenosines; DNA; Hydroxyurea; In Vitro Techniques; Macromolecular Substances; Mice; Mice, Inbred Strains; Phenotype; Protein Biosynthesis; Protein Precursors; Puromycin; RNA; T-Lymphocytes; Thymus Extracts; Transcription, Genetic | 1976 |
[Possibilities and limits of pre-therapeutic neoplasm sensitivity cytostatics tests under short-term conditions].
Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Cricetinae; Cyclophosphamide; Dactinomycin; Daunorubicin; Disease Models, Animal; DNA, Neoplasm; Doxorubicin; Drug Evaluation, Preclinical; Female; Fluorouracil; Humans; Hydroxyurea; Male; Methotrexate; Mice; Procarbazine; Rats; RNA, Neoplasm; Time Factors; Triaziquone; Vincristine | 1975 |
Iridoplegia and aqueous flare due to acute herpetic keratouveitis.
Topics: Acute Disease; Animals; Aqueous Humor; Dactinomycin; Eye Diseases; Eye Proteins; Hydroxyurea; Iris; Keratitis, Dendritic; Paralysis; Rabbits; Time Factors; Uveitis | 1975 |
Sequential irreversible, actinomycin D-sensitive, and cycloheximide-sensitive steps prior to cortisol inhibition of uridine utilization by P1798 tumor lymphocytes.
Topics: Animals; Cycloheximide; Dactinomycin; Depression, Chemical; Female; Hydrocortisone; Hydroxyurea; Lymphocytes; Mice; Mice, Inbred BALB C; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Phenylalanine; Protein Biosynthesis; RNA; RNA, Neoplasm; Thymidine; Time Factors; Transcription, Genetic; Uridine | 1975 |
1-beta-D-arabinofuranosylcytosine-induced chromatid breakage: effect of inhibition of DNA synthesis.
Topics: Animals; Benzimidazoles; Cell Division; Cell Line; Chromatids; Cricetinae; Cycloheximide; Cytarabine; Dactinomycin; Depression, Chemical; DNA; DNA Replication; Fibroblasts; Hydroxyurea; Protein Biosynthesis; RNA; Sulfhydryl Compounds | 1975 |
Ribonucleotide reductase activity during amphibian development.
Topics: Amphibians; Animals; Cell Division; Cycloheximide; Dactinomycin; DNA; Embryo, Nonmammalian; Female; Fertilization; Hydroxyurea; Metamorphosis, Biological; Ovulation; Ovum; Ribonucleotide Reductases; Species Specificity; Uridine; Xenopus | 1975 |
Inhibitor effects during the cell cycle in Chlamydomonas reinhardtii. Determination of transition points in asynchronous cultures.
Topics: Acridines; Anti-Bacterial Agents; Bromouracil; Cell Division; Chlamydomonas; Chloramphenicol; Colchicine; Cycloheximide; Dactinomycin; Dinitrophenols; Dose-Response Relationship, Drug; Ethidium; Hydroxyurea; Mitosis; Rifampin | 1975 |
The effects of a glucocorticoid on the cell surface of RLC-GAI cells.
Topics: Cell Line; Cell Membrane; Cell Movement; Colchicine; Cytochalasin B; Dactinomycin; Dexamethasone; Hydroxyurea; Phosphates; Progesterone; RNA; Sodium | 1975 |
Chemotherapy of melanoma.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carmustine; Cyclophosphamide; Dacarbazine; Dactinomycin; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Nitrosourea Compounds; Semustine; Skin Neoplasms; Vinca Alkaloids | 1975 |
DNA synthesis in permeabilized mouse L cells.
Topics: Biological Transport; Cell Membrane Permeability; Cell Nucleus; Cold Temperature; Cytarabine; Dactinomycin; Deoxyribonucleotides; DNA Replication; Ethylmaleimide; Hydroxymercuribenzoates; Hydroxyurea; Kinetics; L Cells; Magnesium; Microscopy, Electron; Ribonucleotides; Thymidine Kinase | 1976 |
Non-Hodgkin's lymphoma in children. A comparative study of two modalities of therapy.
Topics: Adolescent; Antineoplastic Agents; Asparaginase; Carmustine; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Lymphoma; Male; Mercaptopurine; Methotrexate; Neoplasm Metastasis; Prednisone; Thioguanine; Vinblastine; Vincristine | 1976 |
Induction of DNA polymerase alpha during liver regeneration in rats on controlled feeding schedules.
Topics: Animals; Cell Nucleus; Chromatography, DEAE-Cellulose; Cycloheximide; Dactinomycin; DNA; DNA Nucleotidyltransferases; Eating; Enzyme Induction; Ethylmaleimide; Hepatectomy; Hydroxyurea; Liver Regeneration; Male; Rats; Thymidine | 1976 |
Inhibition of S-phase progression in macrophages is linked to G1/S-phase suppression of DNA synthesis genes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Cycle; Cycloheximide; Dactinomycin; DNA; Female; Gene Expression; Growth Inhibitors; Hydroxyurea; Macrophage Colony-Stimulating Factor; Macrophages; Male; Mice; Mice, Inbred CBA; Mitogens; Nuclear Proteins; Proliferating Cell Nuclear Antigen; Ribonucleotide Reductases; RNA, Messenger | 1992 |
Factors affecting the mRNA levels for the non-heme iron and effector-binding subunits of ribonucleotide reductase.
Topics: Animals; Calcium; Cycloheximide; Cytarabine; Dactinomycin; Deoxyadenosines; Gene Expression Regulation, Neoplastic; Hydroxyurea; Leukemia L1210; Metalloproteins; Nonheme Iron Proteins; Protein Biosynthesis; Pyrazoles; Ribonucleotide Reductases; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1992 |
Prostaglandins A and J arrest the cell cycle of cultured vascular smooth muscle cells without suppression of c-myc expression.
Topics: Animals; Cell Cycle; Cells, Cultured; Dactinomycin; Drug Administration Schedule; Gene Expression; Genes, myc; Hydroxyurea; In Vitro Techniques; Muscle, Smooth, Vascular; Prostaglandin D2; Prostaglandins A; RNA, Messenger; Swine | 1992 |
Granulocyte-macrophage colony-stimulating factor enhances cationic antimicrobial protein synthesis by human neutrophils.
Topics: Antimicrobial Cationic Peptides; Blood Bactericidal Activity; Blood Proteins; Chromatography, Ion Exchange; Colony-Stimulating Factors; Cycloheximide; Dactinomycin; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Hydroxyurea; In Vitro Techniques; Molecular Weight; Neutrophils; Puromycin | 1990 |
Synergistic enhancement by tumor necrosis factor of in vitro cytotoxicity from chemotherapeutic drugs targeted at DNA topoisomerase II.
Topics: Animals; Bleomycin; Cell Line; Cell Survival; Cytarabine; Dactinomycin; DNA Topoisomerases, Type II; Doxorubicin; Drug Synergism; Etoposide; Fibrosarcoma; Glycoproteins; Hydroxyurea; Mice; Recombinant Proteins; Teniposide; Tumor Necrosis Factor-alpha | 1987 |
Variation of tubulin half-life during the cell cycle in the synchronous plasmodia of Physarum polycephalum.
Topics: Cycloheximide; Dactinomycin; DNA, Fungal; Floxuridine; Half-Life; Hydroxyurea; Interphase; Mitosis; Physarum; Radioimmunoassay; Temperature; Thymidine Kinase; Tubulin | 1989 |
Crithidia luciliae: factors affecting the expression of 3'-nucleotidase/nuclease activity.
Topics: Adenosine; Animals; Arginine; Arsenic; Arsenites; Crithidia; Culture Media; Cycloheximide; Dactinomycin; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Hemin; Hydroxyurea; Molecular Weight; Nucleotidases; Purines; Sodium Compounds; Substrate Specificity; Tunicamycin | 1988 |
EMA/CO regimen in high-risk gestational trophoblastic tumor (GTT).
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dactinomycin; Doxorubicin; Etoposide; Female; Humans; Hydroxyurea; Methotrexate; Middle Aged; Pregnancy; Pregnancy Complications, Neoplastic; Trophoblastic Neoplasms; Uterine Neoplasms; Vincristine | 1988 |
Rat T lymphocyte progenitors in bone marrow can be induced to express more Thy 1.
Topics: Animals; Antigens, Surface; Bone Marrow; Bone Marrow Cells; Cell Differentiation; Cell Line; Cell Separation; Dactinomycin; Epithelial Cells; Erythromycin; Flow Cytometry; Hydroxyurea; Imidazoles; Isoproterenol; Propranolol; Rats; T-Lymphocytes; Thy-1 Antigens | 1985 |
Analysis of the activity of DNA, RNA, and protein synthesis inhibitors on Xenopus embryo development.
Topics: Abnormalities, Drug-Induced; Animals; Cycloheximide; Cytarabine; Dactinomycin; DNA Replication; Drug Evaluation, Preclinical; Embryo, Nonmammalian; Ethidium; Female; Hydroxyurea; Protein Biosynthesis; Teratogens; Transcription, Genetic; Xenopus | 1985 |
Modified Bagshawe's regimen in high-risk gestational trophoblastic disease.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Hematopoietic System; Humans; Hydroxyurea; Leucovorin; Methotrexate; Middle Aged; Neoplasm Metastasis; Pregnancy; Risk; Time Factors; Trophoblastic Neoplasms; Uterine Neoplasms; Vincristine | 1986 |
Variable effects of DNA-synthesis inhibitors upon DNA methylation in mammalian cells.
Topics: Animals; Aphidicolin; Base Sequence; Cell Line; Chromatography, High Pressure Liquid; Cricetinae; Cycloheximide; Cytarabine; Dactinomycin; Diterpenes; DNA; DNA Polymerase II; DNA Replication; Fibrosarcoma; Hydroxyurea; Methylation; Nalidixic Acid; Novobiocin | 1986 |
Expression of membrane activation antigens on murine B lymphocytes stimulated with lipopolysaccharide.
Topics: Animals; Antibodies, Monoclonal; Antigens, Differentiation, B-Lymphocyte; B-Lymphocytes; Cell Cycle; Dactinomycin; Flow Cytometry; Hydroxyurea; Lipopolysaccharides; Lymphocyte Activation; Mice; Receptors, Transferrin; Time Factors | 1988 |
Phase II evaluation of dibromodulcitol and actinomycin D, hydroxyurea, and cyclophosphamide in previously untreated patients with malignant melanoma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dactinomycin; Drug Evaluation; Female; Humans; Hydroxyurea; Male; Melanoma; Middle Aged; Mitolactol; Semustine | 1987 |
Detection of inhibitors of protein and nucleic acid synthesis using oocytes of Xenopus laevis microinjected with the herpes thymidine kinase gene.
Topics: Animals; Cycloheximide; Cytarabine; Dactinomycin; Emetine; Ethidium; Female; Genes; Hydroxyurea; Microinjections; Oocytes; Protein Biosynthesis; Puromycin; Thymidine Kinase; Transcription, Genetic; Xenopus | 1986 |
On the role of the spleen in Friend virus (F-MuLV-P) erythroleukemia.
Topics: Animals; Dactinomycin; Endotoxins; Erythropoiesis; Female; Friend murine leukemia virus; Hematocrit; Hydroxyurea; Leukemia, Erythroblastic, Acute; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Phenylhydrazines; Reticulocytes; Salmonella; Spleen; Splenectomy | 1985 |
Does amrinone inhibition of stimulated bone resorption involve Na+-Ca++ exchange?
Topics: Aminopyridines; Amrinone; Animals; Bone Resorption; Calcium; Cardiotonic Agents; Cycloheximide; Dactinomycin; Hydroxyurea; In Vitro Techniques; Ion Exchange; Leucine; Mice; Parathyroid Hormone; Rats; Rats, Inbred Strains; Sodium; Thymidine; Uridine | 1986 |
FACS analysis of a hyperthermia-induced alteration in Hoechst 33342 permeability and direct measurement of its relationship to cell survival.
Topics: Animals; Benzimidazoles; Cell Line; Cell Membrane Permeability; Cell Separation; Cell Survival; Cricetinae; Cricetulus; Dactinomycin; DNA; Female; Fever; Flow Cytometry; Hot Temperature; Hydroxyurea; Kinetics; Ovary; Trypan Blue | 1985 |
[Estimation of tumor sensitivity in vitro. II. Studies with the solid Ehrlich carcinoma of the mouse and the GW 77, a heterotransplanted human carcinoma].
Topics: Animals; Antibiotics, Antineoplastic; Autoradiography; Carcinoma; Carcinoma, Ehrlich Tumor; Colonic Neoplasms; Cricetinae; Culture Media; Cytarabine; Dactinomycin; DNA, Neoplasm; Humans; Hydroxyurea; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Nucleosides; RNA, Neoplasm; Thymidine; Triaziquone; Tritium; Uridine | 1970 |
Synthesis of macromolecules and morphogenesis in acetabularia.
Topics: Acetabularia; Acid Phosphatase; Centrifugation, Density Gradient; Chlorophyta; Chloroplasts; Dactinomycin; Depression, Chemical; DNA Replication; Floxuridine; Hydroxyurea; Isoenzymes; Macromolecular Substances; Microscopy, Electron; Morphogenesis; Photosynthesis; Protein Biosynthesis; Puromycin; Ribosomes; RNA; RNA, Messenger | 1968 |
A simple, rapid technique for determination of the effects of chemotherapeutic agents on mammalian cell-cycle traverse.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Autoradiography; Bleomycin; Carbazoles; Cell Line; Cricetinae; Dactinomycin; Depression, Chemical; DNA; Hydroxyurea; In Vitro Techniques; Methods; Mitosis; Proteins; Puromycin; Threonine; Thymidine; Tritium | 1972 |
Flow microfluorometric analysis of cell killing with cytotoxic drugs.
Topics: Autoanalysis; Bleomycin; Cell Division; Cell Line; Cell Survival; Cytarabine; Dactinomycin; Demecolcine; DNA, Neoplasm; Histocytochemistry; Humans; Hydroxyurea; Leukemia, Myeloid; Methods; Microscopy, Fluorescence; Mitosis; Staining and Labeling; Thymidine; Time Factors; Tritium | 1974 |
Proceedings: Carcinoma of the oral cavity--general principles of therapy.
Topics: Azirines; Bleomycin; Carcinoma, Squamous Cell; Cryosurgery; Dactinomycin; Doxorubicin; Head and Neck Neoplasms; Humans; Hydroxyurea; Mouth Neoplasms; Neoplasm Metastasis; Zinc | 1974 |
Chemotherapy of induced skin tumors in mice.
Topics: Alkylating Agents; Animals; Antimetabolites; Antineoplastic Agents; Benz(a)Anthracenes; Busulfan; Carcinoma, Squamous Cell; Chlorambucil; Cortisone; Cyclophosphamide; Dactinomycin; Estradiol; Female; Fluorouracil; Hydroxyurea; Mercaptopurine; Methotrexate; Mice; Mitomycins; Neoplasms, Experimental; Nitrogen Mustard Compounds; Nitroso Compounds; Papilloma; Skin Neoplasms; Testosterone; Triethylenemelamine | 1968 |
Differential inhibition of protein synthesis in the nucleus and cytoplasm of HeLa cells in the presence of actinomycin, puromycin and hydroxyurea.
Topics: Amino Acids; Cell Nucleus; Culture Techniques; Cytoplasm; Dactinomycin; Depression, Chemical; DNA; Electrophoresis, Disc; HeLa Cells; Histones; Hydroxyurea; Lysine; Nucleoproteins; Proline; Protein Biosynthesis; Puromycin; Spectrophotometry; Thymidine; Tritium | 1969 |
Differential inhibition by actinomycin, puromycin and hydroxyurea of protein synthesis in the nucleus and cytoplasm of chick embryo erythroblasts.
Topics: Amino Acids; Animals; Carbon Isotopes; Cell Nucleus; Chick Embryo; Cytoplasm; Dactinomycin; DNA Replication; Electrophoresis, Disc; Erythrocytes; Histones; Hydroxyurea; Nucleosides; Puromycin; RNA | 1969 |
Fluctuations in deoxycytidine monophosphate deaminase activity during the cell cycle in synchronous populations of HeLa cells.
Topics: Aminohydrolases; Autoradiography; Carbon Isotopes; Cell Line; Cycloheximide; Cytosine Nucleotides; Dactinomycin; Female; HeLa Cells; Humans; Hydroxyurea; Mitosis; Thymidine; Time Factors; Tritium; Uterine Cervical Neoplasms | 1969 |
A cytochemical and ultrastructural analysis of in vitro maturation in amphibian oocytes.
Topics: Amphibians; Animals; Anura; Carbon Isotopes; Cycloheximide; Cytoplasmic Granules; Dactinomycin; DNA; Female; Glycogen; Hydroxyurea; Microscopy, Electron; Ovum; Puromycin; RNA; Staining and Labeling; Urodela | 1970 |
Malignant hepatoma in the Bantu.
Topics: Adenoma, Bile Duct; Africa, Eastern; Alanine Transaminase; Antineoplastic Agents; Aspartate Aminotransferases; Black People; Blood Proteins; Carcinoma, Hepatocellular; Clinical Enzyme Tests; Cyclophosphamide; Cytarabine; Dactinomycin; Fluorouracil; gamma-Globulins; Humans; Hydroxyurea; Liver Neoplasms; Male; Mercaptopurine; Methotrexate; Mitomycins; Nitrogen Mustard Compounds; Prednisone; Prognosis; South Africa; Vincristine | 1970 |
An analysis of the development program in relation to RNA metabolism in the ciliate Stylonychia mytilus.
Topics: Animals; Autoradiography; Cell Division; Ciliophora; Conjugation, Genetic; Dactinomycin; Hydroxyurea; RNA; Thymidine; Tritium | 1974 |
Repair replication of mammalian cell DNA: effects of compounds that inhibit DNA synthesis or dark repair.
Topics: Acridines; Animals; Autoradiography; Bromodeoxyuridine; Caffeine; Centrifugation, Density Gradient; Cycloheximide; Cytosine Nucleotides; Dactinomycin; Depression; DNA; DNA Replication; Floxuridine; Gentian Violet; HeLa Cells; Humans; Hydroxyurea; Iodoacetates; L Cells; Mice; Mitosis; Radiation Effects; Thymidine; Tritium; Ultraviolet Rays | 1969 |
The effect of metabolic inhibitors on the production of vaccinia haemagglutinin.
Topics: Animals; Bromodeoxyuridine; Cattle; Cycloheximide; Cytarabine; Dactinomycin; DNA, Viral; Floxuridine; HeLa Cells; Hemagglutination Inhibition Tests; Hemagglutination Tests; Hemagglutination, Viral; Hemagglutinins, Viral; Humans; Hydroxyurea; Indoles; Mitomycins; Rabbits; Rifampin; Thiosemicarbazones; Vaccinia virus | 1972 |
Chemotherapy for metastatic teratomas of the testis.
Topics: Adult; Antineoplastic Agents; Dactinomycin; Dysgerminoma; Follow-Up Studies; Humans; Hydroxyurea; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Nitrofurazone; Plicamycin; Remission, Spontaneous; Teratoma; Testicular Neoplasms; Vinblastine | 1972 |
Frozen DON cells as a source for a cell cycle assay of antitumor agents.
Topics: Alkaloids; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Biological Assay; Camptothecin; Carbazoles; Cell Division; Cell Line; Cell Survival; Cricetinae; Cryoprotective Agents; Cytarabine; Cytological Techniques; Dactinomycin; Dimethyl Sulfoxide; Floxuridine; Formates; Freezing; Glycerol; Hydroxyurea; Lung; Mitosis; Proteins; Pyridines; Ribonucleosides; Thiosemicarbazones; Time Factors | 1974 |
Factors affecting acid phosphatase activity in exponential and synchronized L5178Y mouse leukemia cells.
Topics: Acid Phosphatase; Animals; Bromodeoxyuridine; Cell Fractionation; Cell Line; Cell Nucleus; Dactinomycin; Daunorubicin; DNA; Electron Transport Complex IV; Hydroxyurea; Leukemia, Experimental; Lucanthone; Mice; Microsomes; Mitochondria; Mitosis; Puromycin; RNA; Thymidine; Time Factors | 1972 |
Nuclear polyadenosine diphosphoribosylation during restricted macromolecular synthesis of HeLa cells.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Carbon Isotopes; Cell Nucleus; Chromatin; Cycloheximide; Cytarabine; Dactinomycin; Deoxyadenosines; DNA; HeLa Cells; Hydroxyurea; NAD; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Protein Biosynthesis; Ribosomes; RNA Nucleotidyltransferases; Thymidine; Tritium; Uridine; Valine | 1972 |
Rescue of vesicular stomatitis virus from interferon-induced resistance by superinfection with vaccinia virus. II. Effect of UV-inactivated vaccinia and metabolic inhibitors.
Topics: Animals; Cell Line; Chick Embryo; Culture Techniques; Dactinomycin; DNA, Viral; Hydroxyurea; Interferons; Kidney; L Cells; Rabbits; Radiation Effects; RNA, Viral; Species Specificity; Time Factors; Tritium; Ultraviolet Rays; Uridine; Vaccinia virus; Vesicular stomatitis Indiana virus; Virus Replication | 1973 |
Enancement of uptake of Simian virus 40 by nuclei of permissive cells.
Topics: Animals; Cell Nucleus; Cells, Cultured; Culture Media; Cycloheximide; Cytarabine; Cytoplasm; Dactinomycin; DNA; Floxuridine; Haplorhini; Histones; Hydroxyurea; Kidney; Kinetics; Magnesium Sulfate; RNA; Simian virus 40; Thymidine; Tritium; Uridine | 1973 |
The relationship between cell growth, macromolecular synthesis and poly ADP-ribose polymerase in lymphoid cells.
Topics: Adenosine Diphosphate; Animals; Cell Division; Cell Line; Cell Nucleus; Cycloheximide; Dactinomycin; DNA; Floxuridine; Hydroxyurea; Lectins; Lymphocytes; Lymphoma; Mice; Mitomycins; NAD; Nucleotidyltransferases; Phenylalanine; Polynucleotide Ligases; Polynucleotides; Protein Biosynthesis; Stimulation, Chemical; Swine; Thymidine; Tritium; Uridine | 1974 |
Regulation of herpesvirus macromolecular synthesis. I. Cascade regulation of the synthesis of three groups of viral proteins.
Topics: Amino Acids; Autoradiography; Carbon Radioisotopes; Carcinoma, Squamous Cell; Cell Line; Cells, Cultured; Cycloheximide; Cytarabine; Dactinomycin; Electrophoresis, Polyacrylamide Gel; Hydroxyurea; Laryngeal Neoplasms; Peptide Biosynthesis; Puromycin; Simplexvirus; Viral Proteins; Virus Replication | 1974 |
Regulation of herpes simplex virus-induced thymidine kinase.
Topics: Animals; Avian Sarcoma Viruses; Cell Line; Cell Transformation, Neoplastic; Cycloheximide; Cytarabine; Dactinomycin; Enzyme Induction; Hydroxyurea; Protein Biosynthesis; RNA, Messenger; RNA, Neoplasm; RNA, Viral; Sarcoma, Avian; Simplexvirus; Thymidine Kinase; Time Factors; Virus Replication | 1974 |
Deoxyribonucleic acid-dependent ribonucleic acid polymerase activity in purified Chlamydia trachomatis initial bodies.
Topics: Centrifugation, Density Gradient; Chlamydia; Dactinomycin; Depression, Chemical; DNA; DNA-Directed RNA Polymerases; Hydroxyurea; Inclusion Bodies; Mercaptoethanol; Nucleosides; Rifampin; RNA, Bacterial; Sodium Chloride; Time Factors; Tritium; Uridine | 1974 |
Effect of metabolic inhibitors on killing of tumor cells by antibody and complement.
Topics: Animals; Antigen-Antibody Reactions; Antimetabolites; Carcinoma, Hepatocellular; Cell Line; Complement System Proteins; Cytotoxicity Tests, Immunologic; Dactinomycin; Guinea Pigs; Hydroxyurea; Liver Neoplasms; Mitomycins; Neoplasms, Experimental; Puromycin; Rabbits; Stimulation, Chemical | 1974 |
Regulation of N-acetylglucosamine kinase synthesis in yeast.
Topics: Acetamides; Acetates; Biological Transport; Candida albicans; Cell Division; Cycloheximide; Dactinomycin; Deoxyadenosines; DNA; Enzyme Induction; Fungal Proteins; Glucosamine; Glucose; Hydroxyurea; Lysine; Mitomycins; Phosphotransferases; Protein Biosynthesis; Thymidine; Time Factors; Tritium | 1974 |
Repair replication of opossum lymphocyte DNA: effect of compounds that bind to DNA.
Topics: Acridines; Alkylating Agents; Animals; Autoradiography; Binding Sites; Bromodeoxyuridine; Centrifugation, Density Gradient; Cycloheximide; Dactinomycin; DNA Repair; DNA Replication; Hydroxyurea; Kinetics; Lymphocytes; Mesylates; Opossums; Quinacrine; Radiation Effects; Thymidine; Tritium; Ultraviolet Rays | 1974 |
Induction of N-acetylglucosamine kinase in yeast.
Topics: Candida albicans; Cycloheximide; Dactinomycin; Enzyme Induction; Fungal Proteins; Glucosamine; Hydroxyurea; Mitomycins; Phosphotransferases; RNA; Thymidine; Time Factors; Uridine | 1974 |
XC-cell fusion induced by murine plasmocytoma cells. I. Alternate "switching off" and "switching on" by "in vivo"-"in vitro" transfers.
Topics: AKR murine leukemia virus; Animals; Antiviral Agents; Cell Fusion; Cell Line; Culture Techniques; Cytopathogenic Effect, Viral; Dactinomycin; Gammaretrovirus; Hydroxyurea; Immune Sera; Injections, Intraperitoneal; Mice; Moloney murine leukemia virus; Phenotype; Plasmacytoma; Rats; Sarcoma, Avian; Virus Replication | 1974 |
Nucleic acid and protein synthesis and pattern regulation in hydra. II. Effect of inhibition of nucleic acid and protein synthesis on hypostome formation.
Topics: Animals; Chloramphenicol; Cnidaria; Cytosine; Dactinomycin; DNA; Fluorouracil; Hydroxyurea; Morphogenesis; Protein Biosynthesis; RNA; RNA, Messenger; Thymidine; Transplantation; Tritium; Uridine | 1969 |
Superinduction of tyrosine aminotransferase by actinomycin D in rat hepatoma (HTC) cells.
Topics: Animals; Antibodies; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Culture Techniques; Dactinomycin; DNA; Enzyme Induction; Hydroxyurea; Liver Neoplasms; Mitomycins; Nucleosides; Rats; RNA; Thymidine; Tyrosine Transaminase; Uridine; Vibration | 1970 |
On the differential cytotoxicity of actinomycin D.
Topics: Animals; Carbon Isotopes; Cell Division; Cell Line; Cell Survival; Cells, Cultured; Culture Techniques; Dactinomycin; DNA; DNA, Neoplasm; Half-Life; Haplorhini; HeLa Cells; Humans; Hydroxyurea; Kidney; L Cells; Lung; Methods; Mice; Protein Biosynthesis; Proteins; RNA; RNA, Neoplasm; Streptovaricin; Time Factors; Uridine | 1971 |
On the translational control of histone synthesis. Quantitation of biologically active histone mRNA from synchronized HeLa cells and its translation in different cell-free systems.
Topics: Animals; Cell Division; Cell-Free System; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Dactinomycin; DNA; Electrophoresis, Polyacrylamide Gel; HeLa Cells; Histones; Humans; Hydroxyurea; Mitosis; Peptide Chain Initiation, Translational; Peptide Initiation Factors; Polyribosomes; Protein Biosynthesis; Rabbits; Reticulocytes; RNA, Messenger; RNA, Neoplasm; Time Factors; Ultrafiltration | 1974 |
RNA-nascent DNA complexes in Ehrlich ascites tumor cells in vivo.
Topics: Animals; Carbon Radioisotopes; Carcinoma, Ehrlich Tumor; Centrifugation, Density Gradient; Chromatography, Paper; Dactinomycin; DNA Replication; DNA, Neoplasm; Hydroxyurea; Male; Mice; Neoplasm Transplantation; RNA, Neoplasm; Thymidine; Tritium; Uridine | 1974 |
Regulation of thymidine kinase synthesis in human cells.
Topics: Carbon Radioisotopes; Carcinoma; Cell Division; Cell Line; Cell-Free System; Cycloheximide; Dactinomycin; DNA Replication; DNA, Neoplasm; Humans; Hydroxyurea; Mitosis; Models, Biological; Mouth Neoplasms; Neoplasm Proteins; Periodicity; RNA, Neoplasm; Thymidine; Thymidine Kinase; Time Factors; Transcription, Genetic; Tritium; Valine | 1974 |
Further characterization of suckling mouse cataract agent (SMCA): a slow, persistent infection of the nervous system.
Topics: Animals; Arboviruses; Bromodeoxyuridine; Cataract; Chick Embryo; Dactinomycin; Filtration; Hot Temperature; Hydrogen-Ion Concentration; Hydroxyurea; Inclusion Bodies, Viral; Kanamycin; Lens, Crystalline; Mice; Micropore Filters; Microscopy, Electron; Nervous System Diseases; Organ Culture Techniques; Particle Size; Penicillin Resistance; Penicillins; Rabbits; Rifampin; Slow Virus Diseases; Streptomycin; Trypsin; Ultraviolet Rays; Virus Replication | 1972 |
Specific increase in pyrimidine deoxynucleoside transport at the time of deoxyribonucleic acid synthesis in 3T3 mouse cells.
Topics: Animals; Biological Transport; Cell Line; Culture Media; Cycloheximide; Cytarabine; Dactinomycin; Deoxyadenosines; Deoxycytidine; Deoxyribonucleosides; DNA; Electrophoresis, Paper; Fibroblasts; Guanosine; Hydroxyurea; Kinetics; Mice; Mitomycins; Mutation; Phosphates; Phosphorus Isotopes; Thymidine; Thymidine Kinase; Time Factors; Tritium | 1973 |
The effects of inhibitors of RNA and DNA synthesis on protein synthesis and polysome levels in mouse L-cells.
Topics: Animals; Benzimidazoles; Centrifugation, Density Gradient; Cycloheximide; Cytarabine; Dactinomycin; Deoxyadenosines; DNA; DNA Replication; Dose-Response Relationship, Drug; Half-Life; Hydroxyurea; Kinetics; L Cells; Mice; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; Peptide Chain Termination, Translational; Phosphorus Radioisotopes; Polyribosomes; Protein Biosynthesis; Pyridines; RNA; RNA, Ribosomal; Sulfhydryl Compounds; Transcription, Genetic; Tritium | 1973 |
The mechanism of the stimulation of LH production by synthetic LH-releasing hormone (LH-RH) in tissue culture.
Topics: Adult; Cells, Cultured; Cycloheximide; Dactinomycin; Female; Gonadotropin-Releasing Hormone; Humans; Hydroxyurea; In Vitro Techniques; Luteinizing Hormone; Pituitary Gland; RNA, Messenger; Time Factors | 1973 |
Observations on induced amitosis in Acanthamoeba.
Topics: Amoeba; Animals; Cell Count; Cell Division; Cell Nucleolus; Cell Nucleus; Colchicine; Culture Media; Cycloheximide; Cytochalasin B; Dactinomycin; Hydroxyurea; Methods; Microscopy, Phase-Contrast; Mitosis; Puromycin; Tritium; Uridine | 1973 |
Immunoreactivity to antinucleoside antibodies in x-irradiated HeLa cells.
Topics: Antibodies; Antigen-Antibody Reactions; Cell Nucleus; Cytarabine; Dactinomycin; DNA, Neoplasm; DNA, Single-Stranded; Dose-Response Relationship, Radiation; Fluorescent Antibody Technique; HeLa Cells; Humans; Hydroxyurea; Immunologic Techniques; Mitosis; Nucleic Acid Denaturation; Nucleosides; Peroxidases; Radiation Effects; Thymidine; Time Factors; Tritium | 1974 |
Regulation of DNA synthesis and cell division in starved-refed synchronized Tetrahymena pyriformis HSM.
Topics: Animals; Autoradiography; Cycloheximide; Dactinomycin; DNA; DNA Nucleotidyltransferases; DNA Replication; Fasting; Hydroxyurea; Mitosis; Proteins; RNA; Tetrahymena; Tetrahymena pyriformis; Thymidine; Time Factors; Tritium; Uridine | 1972 |
Evidence that the synchronized production of new basal bodies is not associated with DNA synthesis in Stentor coeruleus.
Topics: Animals; Autoradiography; Cilia; Ciliophora; Cytarabine; Dactinomycin; DNA; Hydroxyurea; Mitochondria; Mitomycins; Organoids; Protein Biosynthesis; Regeneration; RNA; Thymidine; Tritium | 1972 |
Short-term inhibition of macromolecular synthesis and androgen-induced sexual differentiation of the rat brain.
Topics: Animals; Bromodeoxyuridine; Carbon Isotopes; Cycloheximide; Cytidine; Dactinomycin; DNA; Female; Gonadotropins, Pituitary; Hydroxyurea; Hypothalamo-Hypophyseal System; Hypothalamus; Leucine; Nerve Tissue Proteins; Pituitary Gland; Puromycin; Rats; RNA; Testosterone; Thymidine; Time Factors; Tritium | 1972 |
Effects of inhibitors of protein and nucleic acid synthesis on the expression of H-2 and Moloney leukemia virus-determined cell-surface antigens on cultured murine lymphoma cells.
Topics: Animals; Antigens; Antigens, Neoplasm; Antigens, Viral; Antineoplastic Agents; Cell Membrane; Cells, Cultured; Culture Media; Cycloheximide; Cytarabine; Dactinomycin; Histocompatibility Antigens; Hydroxyurea; Lymphoma; Mice; Mitomycins; Moloney murine leukemia virus; Neoplasm Proteins; Neoplasms, Experimental; Puromycin; RNA, Neoplasm | 1972 |
Mechanism of intestinal radiosensitization by actinomycin D.
Topics: Animals; Cell Division; Dactinomycin; Deoxyuridine; DNA; Hydroxyurea; Iodine Isotopes; Jejunum; Male; Mice; Radiation Effects; Radiation-Sensitizing Agents; Thymidine; Tritium | 1973 |
Effect of inhibiting the cellular synthesis of RNA, DNA and protein on DNA replicative activity of isolated S-phase nuclei.
Topics: Benzimidazoles; Cell Division; Cycloheximide; Dactinomycin; DNA Replication; DNA, Neoplasm; HeLa Cells; Humans; Hydroxyurea; Leucine; Neoplasm Proteins; Pyridines; RNA, Neoplasm; Sulfhydryl Compounds; Thymidine; Thymine Nucleotides; Time Factors; Tritium | 1973 |
Sulfhydryl groups during the S phase: comparison of cells from G 1 , plateau-phase G 1 , and G 0 .
Topics: Animals; Cell Division; Cell Line; Cricetinae; Culture Media; Cycloheximide; Dactinomycin; DNA; Female; Glutathione Reductase; Hydroxyurea; Isoleucine; Isoproterenol; Mice; Ovary; Salivary Glands; Stimulation, Chemical; Sulfhydryl Compounds; Thymidine; Time Factors; Tritium | 1973 |
Effect of chemotherapeutic agents on bladder cancer: a new animal model.
Topics: Animals; Antineoplastic Agents; Carcinoma, Transitional Cell; Cyclophosphamide; Dactinomycin; Diamines; Disease Models, Animal; Doxorubicin; Fluorouracil; Hydroxyurea; Lomustine; Mice; Mice, Inbred C3H; Platinum; Urinary Bladder Neoplasms | 1973 |
Histones and histone synthesis in sea urchin development.
Topics: Animals; Arginine; Blastocyst; Carbon Radioisotopes; Chromatin; Culture Techniques; Dactinomycin; Histones; Hydroxyurea; Leucine; RNA, Messenger; Sea Urchins; Tritium; Valine | 1974 |
Investigational drugs for the treatment of malignant melanoma.
Topics: Alkylating Agents; Amides; Anorexia Nervosa; Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Drug Combinations; Humans; Hydroxyurea; Imidazoles; Leukopenia; Melanoma; Nausea; Thrombocytopenia; Vomiting | 1974 |
Androgen-induced sexual differentiation of the brain is blocked by inhibitors of DNA and RNA synthesis.
Topics: Animals; Animals, Newborn; Brain; Dactinomycin; Depression, Chemical; DNA; Estrus; Female; Fluorouracil; Gonadotropins; Hydroxyurea; Hypothalamus; Mycotoxins; Organ Size; Ovary; Ovulation; Pregnancy; Protein Biosynthesis; Puromycin; Rats; RNA; Sex Factors; Testosterone; Thymidine; Tritium | 1974 |
Inhibition of DNA repair by the 1,3-bis(2-chloroethyl)-1-nitrosourea breakdown product, 2-chloroethyl isocyanate.
Topics: Animals; Carmustine; Cells, Cultured; Cyanates; Cycloheximide; Dactinomycin; Depression, Chemical; DNA Repair; DNA, Neoplasm; DNA, Single-Stranded; Ethylamines; Hydroxyurea; Isocyanates; Leukemia L1210; Mice; Mustard Compounds; Radiation Effects | 1974 |
Biogenesis of poxviruses: role of A-type inclusions and host cell membranes in virus dissemination.
Topics: Animals; Autoradiography; Cell Membrane; Chick Embryo; Chickens; Culture Techniques; Cytarabine; Cytoplasm; Dactinomycin; DNA, Viral; Erythrocytes; Fluorescent Antibody Technique; Genetic Complementation Test; Genetics, Microbial; Goats; Golgi Apparatus; HeLa Cells; Hemadsorption; Hemagglutinins, Viral; Humans; Hydroxyurea; Immune Sera; Inclusion Bodies, Viral; L Cells; Microscopy, Electron; Organelle Biogenesis; Puromycin; Rabbits; Ribosomes; Rifampin; RNA, Viral; Species Specificity; Thymidine; Time Factors; Tritium; Vaccinia virus; Viral Proteins | 1971 |
Cortisol stimulation of growth hormone production by monkey adenohypophysis in tissue culture.
Topics: Animals; Culture Techniques; Cycloheximide; Dactinomycin; Growth Hormone; Haplorhini; Hydrocortisone; Hydroxyurea; Pituitary Gland; RNA | 1968 |
The inhibition of growth of vaccinia and cowpox viruses in RK 13 cells.
Topics: Aniline Compounds; Animals; Antiviral Agents; Azides; Dactinomycin; Hemagglutination Tests; Hydroxyurea; Immunodiffusion; Iodoacetates; Mitomycins; Poxviridae; Rabbits; Vaccinia virus; Virus Cultivation; Virus Replication | 1968 |
The effect of growth inhibitors on postembryonic development in the free-living nematode, Pangrellus silusiae.
Topics: Animals; Anti-Bacterial Agents; Chloramphenicol; Cycloheximide; Dactinomycin; Depression, Chemical; DNA; Enzyme Inhibitors; Ethanol; Hydroxyurea; Leucine; Metabolism; Nalidixic Acid; Nematoda; Nucleic Acids; Protein Biosynthesis; Puromycin; RNA; Thymidine; Time Factors; Tritium; Uridine | 1970 |
Time course of the effect of AAF on mouse liver nucleic acid synthesis and its modification by inhibitors.
Topics: Acetates; Animals; Centrifugation, Density Gradient; Cycloheximide; Dactinomycin; DNA; Fluorenes; Hydroxyurea; Leucine; Liver; Male; Mice; Orotic Acid; Protein Biosynthesis; RNA; RNA Nucleotidyltransferases; RNA, Ribosomal; RNA, Transfer; Thymidine; Time Factors; Tritium; Uridine; Urinary Bladder | 1972 |
Comparative studies on induction and rejoining of DNA single-strand breaks by radiation and chemical carcinogen in mammalian cells in vitro.
Topics: Animals; Bromodeoxyuridine; Carcinogens; Carcinoma, Ehrlich Tumor; Cells, Cultured; Centrifugation, Density Gradient; Dactinomycin; DNA; DNA Repair; DNA Replication; Hot Temperature; Hydroxylamines; Hydroxyurea; Kidney; Kinetics; L Cells; Molecular Weight; Puromycin; Quinolines; Radiation Effects; Swine; Thymidine; Tritium | 1972 |
A direct in vitro assay for studying radiosensitization in mammalian cells.
Topics: Animals; Biopsy; Cells, Cultured; Dactinomycin; DNA Repair; DNA Replication; DNA, Neoplasm; Evaluation Studies as Topic; Hydroxyurea; Leukemia L1210; Mice; Radiation-Sensitizing Agents; Thymidine; Tritium | 1972 |
Radioautographic analysis of 7,12-dimethyl-benz(a)anthracene-3H incorporation and cell survival of Syrian hamster embryo cells during exposure to nucleic acid inhibitors.
Topics: Animals; Autoradiography; Benz(a)Anthracenes; Benzimidazoles; Cell Nucleus; Cricetinae; Culture Techniques; Dactinomycin; DNA; Embryo, Mammalian; Hydroxyurea; Nucleic Acids; RNA; Thymidine; Time Factors; Tritium; Uridine | 1971 |
Regulation of glucose 6-phosphate dehydrogenase formation in mammary organ culture.
Topics: Amino Acids; Animals; Colchicine; Culture Media; Cysteine; Dactinomycin; DNA; Female; Fructose; Glucose; Glucosephosphate Dehydrogenase; Glycerol; Hydroxyurea; Insulin; Kinetics; Mammary Glands, Animal; Mannose; Mice; Mice, Inbred Strains; Mitosis; Organ Culture Techniques; Phosphogluconate Dehydrogenase; Pregnancy; Prolactin; Pyruvates; RNA, Messenger; Thymidine; Time Factors; Tritium | 1971 |
RNA synthesized during differentiation of yolk sac erythroid cells.
Topics: Animals; Carbon Isotopes; Cell Differentiation; Cell Fractionation; Dactinomycin; Electrophoresis; Erythrocytes; Extraembryonic Membranes; Female; Fetal Hemoglobin; Fetal Proteins; Hydroxyurea; Methionine; Mice; RNA; RNA, Messenger; RNA, Ribosomal; Tritium; Uridine | 1971 |
X-ray survival and DNA synthesis in Chinese hamster cells. I. The effect of inhibitors added before x-irradiation.
Topics: Animals; Antifungal Agents; Antineoplastic Agents; Cell Division; Cricetinae; Culture Techniques; Cycloheximide; Dactinomycin; DNA; Hydroxyurea; Radiation Effects; Thymidine; Tritium; Urea | 1967 |
X-radiation survival in mammalian cells and inhibitors of macromolecular synthesis. ANL-7409.
Topics: Animals; Cell Division; Cell Line; Cricetinae; Cycloheximide; Dactinomycin; DNA; Hydroxyurea; Protein Biosynthesis; Radiation Effects; RNA; Thymidine; Time Factors | 1967 |
Ultra-violet-light-enhanced precursor incorporation and the repair of DNA damage.
Topics: Bromodeoxyuridine; Centrifugation, Density Gradient; Culture Techniques; Dactinomycin; DNA; Humans; Hydroxyurea; Kidney; Nucleosides; Radiation Effects; Thymidine; Tritium; Ultraviolet Rays | 1969 |
The influence of post-irradiation conditions on the survival of Chinese hamster cells after gamma-irradiation.
Topics: Acridines; Animals; Caffeine; Chloramphenicol; Cricetinae; Culture Techniques; Cycloheximide; Cytarabine; Dactinomycin; DNA; Hydroxylamines; Hydroxyurea; Protein Binding; Protein Biosynthesis; Puromycin; Radiation Effects; Temperature; Thymidine | 1970 |
Histone synthesis in vitro on HeLa cell microsomes. The nature of the coupling to deoxyribonucleic acid synthesis.
Topics: Benzimidazoles; Cell-Free System; Cytoplasm; Dactinomycin; Depression, Chemical; DNA Replication; DNA, Neoplasm; HeLa Cells; Histones; Hydroxyurea; In Vitro Techniques; Leucine; Lysine; Methods; Microsomes; RNA, Messenger; RNA, Neoplasm; Thymidine; Time Factors; Tritium; Uridine | 1969 |
Synthesis of nuclear and chromosomal proteins on light polyribosomes during cleavage in the sea urchin embryo.
Topics: Animals; Autoradiography; Carbon Isotopes; Cell Division; Cell Nucleus; Chromosomes; Cytoplasm; Dactinomycin; DNA; Echinodermata; Histones; Hydroxyurea; Lysine; Microscopy, Electron; Nucleoproteins; Ribosomes; Tritium; Tryptophan | 1969 |
Synchronized mammalian cell cultures. 3. Variation of ribonucleotide reductase activity during the replication cycle of Chinese hamster fibroblasts.
Topics: Animals; Benzocycloheptenes; Cell Line; Cricetinae; Culture Media; Culture Techniques; Cycloheximide; Dactinomycin; Fibroblasts; Hydroxyurea; Lung; Mitosis; Nucleotides; Oxidoreductases; Phosphorus Isotopes; Protein Biosynthesis; Proteins; Ribonucleotides; RNA; Time Factors; Ultrasonics | 1969 |
Biochemical changes during development of mouse mammary tissue in organ culture.
Topics: Animals; Carbon Isotopes; Caseins; Colchicine; Corticosterone; Culture Techniques; Cycloheximide; Dactinomycin; DNA; Female; Glucose; Hydroxyurea; Insulin; Mammary Glands, Animal; Mice; Organ Culture Techniques; Phosphates; Phosphorus Isotopes; Pregnancy; Prolactin; RNA; Stimulation, Chemical; Thymidine; Tritium; Uridine | 1970 |
Age responses of cultured mammalian cells to cytotoxic drugs.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Benzocycloheptenes; Colchicine; Cricetinae; Culture Techniques; Cycloheximide; Dactinomycin; DNA; Griseofulvin; HeLa Cells; Hydroxylamines; Hydroxyurea; Mechlorethamine; Mitosis; Naphthacenes; Nitrites; Novobiocin; Potassium; Puromycin; RNA; Sulfates; Sulfides; Uracil Mustard; Vinblastine; Vincristine | 1970 |
Early events in in vitro carcinogenesis with 4-nitroquinoline 1-oxide. II. Mode of incorporation and binding of the carcinogen.
Topics: Acids; Animals; Carbon Isotopes; Carcinogens; Cell Line; Cricetinae; Culture Techniques; Dactinomycin; DNA; Embryo, Mammalian; Hydroxyurea; Protein Biosynthesis; Puromycin; Quinolines; RNA; Time Factors; Tritium | 1970 |
Actinomycin D and radiation fractionation studies in asynchronous and synchronized Chinese hamster cells.
Topics: Animals; Cell Division; Cell Line; Cricetinae; Culture Techniques; Dactinomycin; DNA; Hydroxyurea; Radiation Effects; Time Factors | 1970 |
Implications of biochemical, cytokinetic, pharmacologic, and toxicologic relationships in the design of optimal therapeutic schedules.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Disease Models, Animal; DNA, Neoplasm; Fluorouracil; Half-Life; Hydroxyurea; In Vitro Techniques; Kinetics; Leukemia L1210; Mercaptopurine; Methotrexate; Mice; Mitosis; Nitrosourea Compounds; Thiosemicarbazones | 1970 |
Initiation of a differentiated function (hyaluronic acid synthesis) by hybrid formation in culture.
Topics: Animals; Cell Line; Chromatography, Gas; Clone Cells; Cricetinae; Culture Techniques; Dactinomycin; DNA; Hyaluronic Acid; Hybridization, Genetic; Hydroxyurea; Mice; Mucins; RNA; Viscosity | 1970 |
The effect of x-irradiation on thymidine kinase activity in synchronous populations of HeLa cells.
Topics: Cell Division; Chromatography, DEAE-Cellulose; Colchicine; Cycloheximide; Dactinomycin; DNA; HeLa Cells; Hydroxyurea; Periodicity; Radiation Effects; Thymidine; Thymidine Kinase | 1971 |
Studies on the mechanism of action of progesterone in regulation of the synthesis of specific protein.
Topics: Amino Acids; Animals; Chickens; Colchicine; Culture Techniques; Cycloheximide; Dactinomycin; Diethylstilbestrol; Estrogens; Female; Fluorouracil; Hydroxyurea; Mitosis; Muramidase; Ovalbumin; Oviducts; Progesterone; Protein Biosynthesis; RNA; RNA Nucleotidyltransferases; Thymidine; Tritium; Uridine | 1968 |
Viruses and renal carcinoma of Rana pipiens. VI. Interrelationships of macromolecular synthesis and infectious virus production in frog virus 3-infected BHK 21/13 cells.
Topics: Adenine; Animals; Anura; Carbon Isotopes; Culture Techniques; Cycloheximide; Cytarabine; Dactinomycin; DNA; DNA, Viral; Herpesviridae; Hydroxyurea; Idoxuridine; Inclusion Bodies, Viral; Kidney Neoplasms; Leucine; Neoplasms, Experimental; Oncogenic Viruses; Protein Biosynthesis; RNA; RNA, Viral; Thymidine; Tritium; Uridine; Viral Proteins; Virus Replication | 1968 |
Studies on thymidine kinase, thymidylate kinase, and deoxycytidylate deaminase of Chang liver cells.
Topics: Aminohydrolases; Carbon Isotopes; Culture Techniques; Cytosine Nucleotides; Dactinomycin; DNA; Feedback; Growth; Humans; Hydroxyurea; Liver; Methotrexate; Mitomycins; Nucleosides; Nucleotides; Phosphotransferases; Puromycin; Thymidine; Thymidine Kinase; Time Factors | 1968 |
[The formation of cytasters and the metabolism of nucleic acids and proteins in amphibian eggs treated with heavy water].
Topics: Animals; Anura; Carbon Isotopes; Cycloheximide; Dactinomycin; Deuterium; DNA; Female; Hydroxyurea; Leucine; Mercaptoethanol; Nucleic Acids; Organoids; Ovum; Protein Biosynthesis; Puromycin; Radiation Effects; RNA; Urodela | 1968 |
Effects of hydroxyurea (NSC-32065) and actinomycin D (NSC-3053) on several parameters of infection by Friend spleen focus-forming virus.
Topics: Animals; Dactinomycin; Female; Friend murine leukemia virus; Hydroxyurea; Mice; Splenic Diseases; Virus Diseases | 1968 |
DNA synthesis in the developing rat brain.
Topics: Adenine; Aging; Animals; Animals, Newborn; Brain; Brain Chemistry; Carbon Isotopes; Cell-Free System; Cerebellum; Cerebral Cortex; Dactinomycin; Depression, Chemical; DNA; Hydroxyurea; Hypothalamus; Limbic System; Medulla Oblongata; Organ Size; Pons; Rats; RNA; Thymidine | 1969 |
Molecular mechanisms of liver regeneration. VII. Conversion of cytidine to deoxycytidine in rat regenerating livers.
Topics: Adenosine Triphosphate; Animals; Dactinomycin; Depression, Chemical; Hepatectomy; Hydrogen-Ion Concentration; Hydroxyurea; Liver; Liver Regeneration; Male; Nucleosides; Nucleotides; Oxidoreductases; Radiation Effects; Rats; Time Factors | 1969 |
Cell killing by actinomycin D in relation to the growth cycle of chinese hamster cells.
Topics: Animals; Cell Division; Cell Line; Cricetinae; Culture Techniques; Dactinomycin; DNA; Hydroxyurea; Lung; Mitosis; Radiation Effects; Time Factors | 1969 |
Increase in activity of glucose 6-phosphate dehydrogenase in mouse mammary tissue cultured in insulin.
Topics: Adipose Tissue; Animals; Corticosterone; Culture Techniques; Cycloheximide; Dactinomycin; DNA; Female; Glucosephosphate Dehydrogenase; Hydroxyurea; Insulin; Mammary Glands, Animal; Mice; Pregnancy; Prolactin; Puromycin; RNA | 1969 |
Disseminated melanoma. Biologic behavior and treatment.
Topics: Antineoplastic Agents; Chlorambucil; Cyclophosphamide; Dactinomycin; Fluorouracil; Humans; Hydrazines; Hydroxyurea; Lymph Node Excision; Lymphatic Metastasis; Melanoma; Melphalan; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Perfusion; Vincristine | 1967 |
Sub-lethal and lethal radiation damage.
Topics: Animals; Cricetinae; Culture Techniques; Dactinomycin; Hydroxyurea; Mitosis; Radiation Effects | 1967 |
The effect of myo-inositol deficiency on phosphatases of yeast.
Topics: Acid Phosphatase; Cell Count; Dactinomycin; Hydroxyurea; Inositol; Phosphoric Monoester Hydrolases; Saccharomyces | 1984 |
Studies on differentiation without cleavage in Chaetopterus variopedatus: requirements for nucleic acid and protein synthesis.
Topics: Animals; Cell Differentiation; Cycloheximide; Dactinomycin; DNA; Dose-Response Relationship, Drug; Emetine; Female; Hydroxyurea; Polychaeta; Protein Biosynthesis; Puromycin; RNA; Time Factors; Zygote | 1980 |
Chemotherapy with the modified Bagshawe protocol for poor prognosis metastatic trophoblastic disease.
Topics: Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Leucovorin; Methotrexate; Neoplasm Metastasis; Pregnancy; Prognosis; Trophoblastic Neoplasms; Uterine Neoplasms; Vincristine | 1982 |
Studies on corneal endothelial growth and repair. III. Effects of DNA and RNA synthesis inhibitors upon restoration of transparency following injury.
Topics: Animals; Cell Count; Cornea; Corneal Injuries; Dactinomycin; DNA; Endothelium; Hydroxyurea; Rana pipiens; RNA; Wound Healing | 1982 |
Flow cytometric analysis of RNA content in different cell populations using pyronin Y and methyl green.
Topics: Animals; Cells, Cultured; Dactinomycin; Demecolcine; DNA; Flow Cytometry; Humans; Hydroxyurea; Interphase; Lymphocyte Activation; Lymphocytes; Methyl Green; Mice; Mitosis; Neoplasms, Experimental; Pyronine; Rats; RNA; RNA, Neoplasm; Rosaniline Dyes; Staining and Labeling; Xanthenes | 1982 |
Soft agar colony formation assay for in vitro chemotherapy sensitivity testing of human renal cell carcinoma: Mayo Clinic experience.
Topics: Adenocarcinoma; Agar; Antineoplastic Agents; Bleomycin; Cells, Cultured; Dactinomycin; Drug Evaluation; Humans; Hydroxyurea; Kidney Neoplasms; Mitoguazone; Nephrectomy; Teniposide | 1984 |
Induction of endogenous murine type C virus by ultraviolet-irradiated herpes simplex virus: effect of metabolic inhibitors.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Dactinomycin; DNA, Neoplasm; Hydroxyurea; Mice; Retroviridae; RNA, Neoplasm; Sarcoma Viruses, Murine; Simplexvirus; Ultraviolet Rays; Virus Activation | 1980 |
Activation of an endogenous mouse type C virus by UV-irradiated murine cytomegalovirus.
Topics: Animals; Cytomegalovirus; Dactinomycin; Hydroxyurea; Kirsten murine sarcoma virus; Mice; Mice, Inbred Strains; Sarcoma, Experimental; Ultraviolet Rays; Virus Activation | 1982 |
Inhibition of DNA replication coordinately reduces cellular levels of core and H1 histone mRNAs: requirement for protein synthesis.
Topics: Aphidicolin; Cycloheximide; Cytarabine; Dactinomycin; Diterpenes; DNA Polymerase II; DNA Replication; HeLa Cells; Histones; Humans; Hydroxyurea; Kinetics; Protein Biosynthesis; RNA, Messenger; Transcription, Genetic | 1984 |
Potentiative interactions between caffeine and various teratogenic agents.
Topics: Abnormalities, Drug-Induced; Acetazolamide; Animals; Caffeine; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Drug Synergism; Emetine; Female; Fetal Death; Floxuridine; Hydroxyurea; Pregnancy; Rats; Rats, Inbred Strains | 1982 |
1 alpha, 25-Dihydroxyvitamin D3 directly induces fusion of alveolar macrophages by a mechanism involving RNA and protein synthesis, but not DNA synthesis.
Topics: Animals; Calcitriol; Cell Fusion; Cycloheximide; Dactinomycin; DNA Replication; Hydroxyurea; Kinetics; Macrophages; Male; Mice; Mice, Inbred Strains; Protein Biosynthesis; Transcription, Genetic | 1984 |
Level of mIa expression on mitogen-stimulated murine B lymphocytes is dependent on position in cell cycle.
Topics: Animals; Antigens, Surface; B-Lymphocytes; Cell Cycle; Dactinomycin; Flow Cytometry; Histocompatibility Antigens Class II; Hydroxyurea; Interphase; Lipopolysaccharides; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Vinblastine | 1983 |
Potential pre-screening for therapeutic agents that induce differentiation in human myeloid leukemia cells.
Topics: Antineoplastic Agents; Bromodeoxyuridine; Cell Line; Cell Transformation, Neoplastic; Complement C3; Cytarabine; Dactinomycin; Doxorubicin; Humans; Hydroxyurea; Immunoglobulin Fc Fragments; Leukemia, Myeloid; Leukocytes; Mitomycins; Muramidase; Rosette Formation | 1980 |
Platelet-derived growth factor in chemotactic for fibroblasts.
Topics: Blood Platelets; Cells, Cultured; Chemotaxis; Cycloheximide; Dactinomycin; Fibroblasts; Growth Substances; Humans; Hydroxyurea; Male; Mast Cells; Neutrophils; Peptides; Platelet-Derived Growth Factor | 1982 |
Dietary sucrose-mediated changes in jejunal sucrase activity of rats.
Topics: Animals; Dactinomycin; Dietary Carbohydrates; Hydroxyurea; Jejunum; Male; Rats; Sucrase; Sucrose; Surface-Active Agents | 1980 |
Protection of cycling CFUs against hydroxyurea by low doses of actinomycin D.
Topics: Animals; Autoradiography; Carcinoma, Ehrlich Tumor; Cell Division; Colony-Forming Units Assay; Dactinomycin; Dose-Response Relationship, Drug; Female; Hematopoietic Stem Cells; Hydroxyurea; Mice; Neoplasm Transplantation | 1980 |
Inhibition of bone resorption by selective inactivators of cysteine proteinases.
Topics: Animals; Bone Resorption; Calcitriol; Cells, Cultured; Cysteine Proteinase Inhibitors; Dactinomycin; DNA; Dose-Response Relationship, Drug; Humans; Hydroxyurea; Kinetics; Mice; Parathyroid Hormone; Protein Biosynthesis; Skull; Time Factors | 1994 |
Chemotherapy combined with surgery in the treatment of gestational trophoblastic disease (GTD).
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Choriocarcinoma; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Resistance; Etoposide; Female; Humans; Hydatidiform Mole; Hydroxyurea; Hysterectomy; Lung Neoplasms; Methotrexate; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Pregnancy; Salvage Therapy; Thoracotomy; Treatment Outcome; Trophoblastic Neoplasms; Uterine Hemorrhage; Uterine Neoplasms; Vincristine | 1993 |
Measurement of DNA integrity and structure in Xenopus embryos in the presence of hydroxyurea, actinomycin-D, and triethylenemelamine using the fluorescent probe Hoechst 33258.
Topics: Animals; Antineoplastic Agents; Bisbenzimidazole; Cattle; Dactinomycin; DNA; Dose-Response Relationship, Drug; Embryo, Nonmammalian; Female; Fluorescent Dyes; Histones; Hydroxyurea; Male; Teratogens; Thymus Gland; Triethylenemelamine; Xenopus laevis | 1995 |
Cell cycle effects of nitric oxide on vascular smooth muscle cells.
Topics: Animals; Aorta, Thoracic; Cell Cycle; Cell Division; Cells, Cultured; Cyclic GMP; Dactinomycin; DNA; Flow Cytometry; G2 Phase; Glutathione; Hydroxyurea; Kinetics; Male; Mitochondria, Muscle; Mitosis; Muscle, Smooth, Vascular; Nitric Oxide; Nitroso Compounds; Oxygen Consumption; Penicillamine; Rats; Rats, Sprague-Dawley; S Phase; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; Time Factors | 1997 |
Cell-cycle-dependent nuclear translocation of HSP70 in amphibian embryonic cells.
Topics: Animals; Aphidicolin; Biological Transport; Cell Nucleus; Dactinomycin; DNA Replication; Embryo, Nonmammalian; Gastrula; HSP70 Heat-Shock Proteins; Hydroxyurea; Nucleic Acid Synthesis Inhibitors; Pleurodeles; S Phase; Transcription, Genetic | 1998 |
Chemotherapy for gestational trophoblastic tumours hastens menopause by 3 years.
Topics: Adult; Antineoplastic Agents; Choriocarcinoma; Dactinomycin; Etoposide; Female; Follow-Up Studies; Humans; Hydroxyurea; Leucovorin; Menopause, Premature; Mercaptopurine; Methotrexate; Middle Aged; Pregnancy; Retrospective Studies; Risk Factors; Trophoblastic Neoplasms | 1998 |
Induction of catecholamine synthesis in human neuroblastoma cells by replication inhibitors and sodium butyrate.
Topics: Amanitins; Antineoplastic Agents; Butyrates; Cyclic AMP; Cycloheximide; Dactinomycin; DNA Replication; Dopamine; Homovanillic Acid; Humans; Hydroxyurea; Kinetics; Neuroblastoma; Norepinephrine; Thymidine; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase; Vanilmandelic Acid | 1999 |
Novobiocin is a novel inducer of CD38 on cells of the myelomonocytic lineage.
Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Anti-Bacterial Agents; Antigens, CD; Antigens, Differentiation; Cell Differentiation; Cell Division; Dactinomycin; Dexamethasone; Dose-Response Relationship, Drug; HL-60 Cells; Humans; Hydroxyurea; Leukopoiesis; Membrane Glycoproteins; NAD+ Nucleosidase; Novobiocin; Transcription, Genetic; Tumor Cells, Cultured | 2002 |
TRIAL OF HYDROXYUREA (NSC-32065) IN CANCER IN CHILDREN.
Topics: Antineoplastic Agents; Busulfan; Child; Cyclophosphamide; Dactinomycin; Humans; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mercaptopurine; Neoplasms; Neuroblastoma; Sarcoma; Urea | 1964 |
Nuclear DNA helicase II (RNA helicase A) binds to an F-actin containing shell that surrounds the nucleolus.
Topics: Actins; Active Transport, Cell Nucleus; Animals; Autoantigens; Binding Sites; Cell Compartmentation; Cell Cycle; Cell Line, Tumor; Cell Nucleolus; Dactinomycin; DEAD-box RNA Helicases; Gelsolin; Humans; Hydroxyurea; Mice; Neoplasm Proteins; NIH 3T3 Cells; Nucleolin; Phosphoproteins; Pol1 Transcription Initiation Complex Proteins; Polymers; Protein Binding; RNA Helicases; RNA-Binding Proteins; RNA, Ribosomal; Tumor Suppressor Protein p53 | 2004 |
Relative cytotoxicity values at the lowest effective concentration for 12 positive chemicals in the in vitro micronucleus test utilizing Chinese hamster ovary cells.
Topics: Animals; Benz(a)Anthracenes; Bleomycin; Cell Count; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Cyclophosphamide; Dactinomycin; Dose-Response Relationship, Drug; Etoposide; Female; Griseofulvin; Hazardous Substances; Hydrogen Peroxide; Hydroxyurea; Methyl Methanesulfonate; Mitomycin; Phenol; Vinblastine | 2004 |
Maternal and perinatal outcomes of first pregnancy after chemotherapy for gestational trophoblastic neoplasia in Brazilian women.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brazil; Cisplatin; Cohort Studies; Cyclophosphamide; Dactinomycin; Doxorubicin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Hydroxyurea; Methotrexate; Pregnancy; Pregnancy Outcome; Retrospective Studies; Risk Factors; Vincristine | 2009 |
An indirect role for ASPP1 in limiting p53-dependent p21 expression and cellular senescence.
Topics: Acyltransferases; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Apoptosis Regulatory Proteins; Cell Cycle Proteins; Cell Line, Tumor; Cellular Senescence; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Dactinomycin; DNA Replication; DNA-Binding Proteins; Doxorubicin; Gene Expression Regulation; Humans; Hydroxyurea; Nuclear Proteins; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; RNA, Small Interfering; Transcription Factors; Transcription, Genetic; Tumor Protein p73; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2012 |
Cyclophosphamide, hydroxyurea, actinomycin D, methotrexate, and vincristine in the treatment of gestational trophoblastic neoplasia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dactinomycin; Female; Gestational Trophoblastic Disease; Humans; Hydroxyurea; Methotrexate; Neoplasm Recurrence, Local; Neutropenia; Pregnancy; Retrospective Studies; Salvage Therapy; Stomatitis; Survival Rate; Treatment Outcome; Vincristine; Vomiting | 2015 |