hydroxyurea and cyclosporine

hydroxyurea has been researched along with cyclosporine in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (25.00)18.2507
2000's14 (38.89)29.6817
2010's11 (30.56)24.3611
2020's2 (5.56)2.80

Authors

AuthorsStudies
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Kumar, L1
Harrison, PE; Menter, A; Morris, LF; Phillips, CM; Sander, HM1
Bjerring, P; Heickendorff, L; Zachariae, H1
Cervantes, F; Esteve, J; Marín, P; Montserrat, E; Rozman, C; Sanz, L; Vilardell, J1
Schiff, M1
Harrison, PV; Kirby, B1
Colombel, JF; Desreumaux, P; Ectors, N; Geboes, K; Jouret, A; Rutgeerts, P1
Lisziewicz, J; Lori, F; Ravot, E1
Hardeman, MR; Ince, C1
Ansari, AA; Bostik, P; Greenberg, KP; Mayne, AE; Powell, JD; Villinger, F1
Battmer, K; Dammann, E; Eder, M; Ganser, A; Hambach, L; Heil, G; Hertenstein, B; Stucki, A1
Ait Arkoub, Z; Arnulf, B; Chebbi, F; Fillet, AM; Lefrere, F; Varet, B1
Kormeili, T; Lowe, NJ; Patnaik, R; Rizk, D; Yamauchi, PS1
Kawauchi, K; Ogasawara, T; Ohkawa, S; Takei, K; Yasuyama, M1
Menon, K; Siu, K; Strober, BE1
de Reyes, G; Flores, A; Howard, SC; Machin, S; Masera, G; Navarrete, M; Nieves, R; Pacheco, C; Rodriguez, H; Svarch, E; Wilimas, JA1
Balkrishnan, R; Camacho, F; Crane, MM; Feldman, SR; Fleischer, AB; Higgins, KB; Pearce, DJ; Stealey, KH1
Barletta, J; Bergström, M; Blomquist, G; Långström, B; Syvänen, S1
Bochner, BS; Butterfield, JH; Gleich, GJ; Huss-Marp, J; Kahn, JE; Klion, AD; Leiferman, KM; Nutman, TB; Ogbogu, PU; Pfab, F; Ring, J; Rothenberg, ME; Roufosse, F; Sajous, MH; Sheikh, J; Simon, D; Simon, HU; Stein, ML; Wardlaw, A; Weller, PF1
Foley, P; Kelly, JB; Strober, BE1
Balleari, E; Bernal, T; Beyne-Rauzy, O; Bordessoule, D; Calabuig, M; Cametti, G; Campelo, MD; Cheze, S; Cony-Makhoul, P; Dreyfus, F; Fenaux, P; Fensterl, J; Ferrero, D; Gaidano, G; Germing, U; Gioia, D; Götze, K; Guerci-Bresler, A; Hamel, JF; Kaivers, J; Kelaidi, C; Komrokji, R; Kotsianidis, I; Müller-Thomas, C; Pane, F; Park, S; Ramos, F; Roboz, GJ; Rose, C; Sanna, A; Santini, V; Sanz, GF; Sapena, R; Sekeres, MA; Stamatoullas, A; Steensma, DP; Thépot, S; Toma, A; Vey, N; Wattel, E1
Lim, YL; Toh, JJ; Yew, YW1
Chen, LYC; Dou, C; Williams, AK1

Reviews

10 review(s) available for hydroxyurea and cyclosporine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Chronic myeloid leukemia: management of relapse after allogeneic bone marrow transplantation.
    Leukemia & lymphoma, 1993, Volume: 10, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Clinical Trials as Topic; Cyclosporine; Graft Enhancement, Immunologic; Graft vs Host Disease; Humans; Hydroxyurea; Immunologic Factors; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Remission Induction; Reoperation; Risk Factors; Salvage Therapy; Survival Rate; Treatment Outcome

1993
Emerging treatments for rheumatoid arthritis.
    The American journal of medicine, 1997, Jan-27, Volume: 102, Issue:1A

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antibodies; Antirheumatic Agents; Arthritis, Rheumatoid; CD4 Antigens; Collagen; Cyclosporine; Humans; Hydroxyurea; Immunosuppressive Agents; Interleukin-1; Minocycline; Mycophenolic Acid; Tumor Necrosis Factor-alpha

1997
[Histopathologic diagnosis of the activity of chronic inflammatory bowel disease. Evaluation of the effect of drug treatment. Use of histological scores].
    Gastroenterologie clinique et biologique, 1999, Volume: 23, Issue:10

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Biopsy; Colitis, Ulcerative; Colon; Crohn Disease; Cyclosporine; Humans; Hydroxyurea; Ileum; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mesalamine; Microscopy; Sulfasalazine; Time Factors

1999
New uses for old drugs in HIV infection: the role of hydroxyurea, cyclosporin and thalidomide.
    Drugs, 1999, Volume: 58, Issue:6

    Topics: Cyclosporine; HIV Infections; Humans; Hydroxyurea; Immunosuppressive Agents; Nucleic Acid Synthesis Inhibitors; Thalidomide

1999
Donor cell-derived acute myeloid leukemia developing 14 months after matched unrelated bone marrow transplantation for chronic myeloid leukemia.
    Bone marrow transplantation, 2001, Volume: 28, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Bone Marrow Transplantation; Combined Modality Therapy; Cyclosporine; Cystitis; Cytarabine; Cytomegalovirus Infections; DNA, Neoplasm; Female; Foscarnet; Ganciclovir; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Histocompatibility; Humans; Hydroxyurea; Immunosuppressive Agents; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Methotrexate; Mitoxantrone; Neoplasms, Second Primary; Prednisolone; Prostaglandins; Remission Induction; Topotecan; Transplantation Conditioning; Transplantation, Homologous; Vidarabine; Whole-Body Irradiation

2001
Current systemic therapies for psoriasis: where are we now?
    Journal of the American Academy of Dermatology, 2003, Volume: 49, Issue:2 Suppl

    Topics: Acitretin; Antineoplastic Agents; Cyclosporine; Dermatologic Agents; Drug Therapy, Combination; Humans; Hydroxyurea; Keratolytic Agents; Methotrexate; Psoriasis; Remission Induction

2003
Conventional systemic agents for psoriasis. A systematic review.
    The Journal of rheumatology, 2006, Volume: 33, Issue:7

    Topics: Acitretin; Clinical Trials as Topic; Cyclosporine; Drug Therapy, Combination; Evidence-Based Medicine; Humans; Hydroxyurea; Immunosuppressive Agents; Methotrexate; Practice Guidelines as Topic; Psoriasis; Thioguanine; Treatment Outcome

2006
Current and future oral systemic therapies for psoriasis.
    Dermatologic clinics, 2015, Volume: 33, Issue:1

    Topics: Acitretin; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites; Cyclosporine; Fumarates; Humans; Hydroxyurea; Immunosuppressive Agents; Isoxazoles; Keratolytic Agents; Leflunomide; Methotrexate; Mycophenolic Acid; Piperidines; Protein Kinase Inhibitors; Psoriasis; Pyrimidines; Pyrroles; Sulfasalazine; Thalidomide; Thioguanine

2015
Treatment of lymphocyte-variant hypereosinophilic syndrome (L-HES): what to consider after confirming the elusive diagnosis.
    British journal of haematology, 2021, Volume: 195, Issue:5

    Topics: Adrenal Cortex Hormones; Alemtuzumab; Antibodies, Monoclonal; Cyclosporine; Humans; Hydroxyurea; Hypereosinophilic Syndrome; Imatinib Mesylate; Immunologic Factors; Immunosuppressive Agents; Interferon-alpha; Interleukin-5; Lymphocyte Activation; Lymphocytes

2021

Other Studies

26 other study(ies) available for hydroxyurea and cyclosporine

ArticleYear
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
The annual cost of psoriasis.
    Journal of the American Academy of Dermatology, 1993, Volume: 28, Issue:3

    Topics: Adult; Cyclosporine; Etretinate; Female; Health Care Costs; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Phototherapy; Psoriasis; PUVA Therapy; Retrospective Studies; Ultraviolet Therapy

1993
Plasma endothelin in psoriasis: possible relations to therapy and toxicity.
    Acta dermato-venereologica, 1996, Volume: 76, Issue:6

    Topics: Acitretin; Cyclosporine; Endothelins; Humans; Hydroxyurea; Keratolytic Agents; Methotrexate; Psoriasis; Ranitidine

1996
[Chronic myeloid leukemia after renal transplantation: report of a new case and review of the bibliography].
    Sangre, 1996, Volume: 41, Issue:5

    Topics: Adult; Azathioprine; Cyclosporine; Female; Humans; Hydroxyurea; Immunosuppressive Agents; Incidence; Kidney Transplantation; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Postoperative Complications

1996
Combination low-dose cyclosporin (Neoral) and hydroxyurea for severe recalcitrant psoriasis.
    The British journal of dermatology, 1999, Volume: 140, Issue:1

    Topics: Aged; Cyclosporine; Dermatologic Agents; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Male; Middle Aged; Psoriasis

1999
Clinical potential of in vitro measured red cell deformability, a myth?
    Clinical hemorheology and microcirculation, 1999, Volume: 21, Issue:3-4

    Topics: Adult; Age Factors; Anemia, Sickle Cell; Cell Count; Child, Preschool; Cyclosporine; Elliptocytosis, Hereditary; Erythrocyte Deformability; Female; Humans; Hydroxyurea; Immunosuppressive Agents; Malaria; Male; Smith-Lemli-Opitz Syndrome

1999
Relative resistance in the development of T cell anergy in CD4+ T cells from simian immunodeficiency virus disease-resistant sooty mangabeys.
    Journal of immunology (Baltimore, Md. : 1950), 2001, Jan-01, Volume: 166, Issue:1

    Topics: Adult; Animals; Base Sequence; CD4-Positive T-Lymphocytes; Cells, Cultured; Cercocebus atys; Clonal Anergy; Cyclosporine; Cytokines; Epitopes, T-Lymphocyte; Humans; Hydroxyurea; Immunity, Innate; Kinetics; Lymphocyte Activation; Macaca mulatta; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Muromonab-CD3; Simian Acquired Immunodeficiency Syndrome; Sirolimus

2001
Multiple herpes simplex virus infections with various resistance patterns in a matched unrelated donor transplant recipient.
    Bone marrow transplantation, 2001, Volume: 28, Issue:8

    Topics: Acyclovir; Antineoplastic Agents, Alkylating; Antiviral Agents; Bone Marrow Transplantation; Cidofovir; Combined Modality Therapy; Cyclosporine; Cytarabine; Cytomegalovirus Infections; Cytosine; Drug Resistance, Viral; Fatal Outcome; Foscarnet; Graft vs Host Disease; Herpes Genitalis; Herpes Simplex; Humans; Hydroxyurea; Immunocompromised Host; Immunosuppressive Agents; Interferons; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Methotrexate; Middle Aged; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Transplantation Conditioning; Whole-Body Irradiation

2001
[Pure red cell aplasia occurring during the course of chronic myelogenous leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2004, Volume: 45, Issue:1

    Topics: Acute Disease; Antineoplastic Agents; Blood Transfusion; Cyclosporine; Hepatitis C; Humans; Hydroxyurea; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Red-Cell Aplasia, Pure

2004
Treatment for children with severe aplastic anemia and sickle cell disease in low income countries in Latin America: a report on the recent meetings of the Monza International School of Pediatric Hematology/Oncology (MISPHO): Part III.
    Pediatric blood & cancer, 2007, Volume: 48, Issue:5

    Topics: Anemia, Aplastic; Anemia, Sickle Cell; Antilymphocyte Serum; Child; Cyclosporine; Developing Countries; Humans; Hydroxyurea; International Cooperation; Latin America

2007
Adverse events from systemic therapies for psoriasis are common in clinical practice.
    The Journal of dermatological treatment, 2006, Volume: 17, Issue:5

    Topics: Adult; Aged; Biological Products; Cyclosporine; Dermatologic Agents; Female; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Psoriasis; PUVA Therapy; Retinoids; Retrospective Studies

2006
PET-evaluated transport of [11C]hydroxyurea across the rat blood-brain barrier--lack of influence of cyclosporin and probenecid.
    Drug metabolism letters, 2007, Volume: 1, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Brain; Cyclosporine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Hydroxyurea; Male; Mannitol; Positron-Emission Tomography; Probenecid; Rats; Rats, Sprague-Dawley; Tissue Distribution; Verapamil

2007
Hypereosinophilic syndrome: a multicenter, retrospective analysis of clinical characteristics and response to therapy.
    The Journal of allergy and clinical immunology, 2009, Volume: 124, Issue:6

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Benzamides; Chemokine CCL17; Child; Cyclosporine; Drug Therapy, Combination; Eosinophils; Female; Humans; Hydroxyurea; Hypereosinophilic Syndrome; Imatinib Mesylate; Interferon-alpha; Interleukin-5; Male; Middle Aged; mRNA Cleavage and Polyadenylation Factors; Oncogene Proteins, Fusion; Piperazines; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Retrospective Studies; Tryptases; Young Adult

2009
Outcome of Lower-Risk Patients With Myelodysplastic Syndromes Without 5q Deletion After Failure of Erythropoiesis-Stimulating Agents.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, May-10, Volume: 35, Issue:14

    Topics: Aged; Aged, 80 and over; Anemia; Antilymphocyte Serum; Antineoplastic Agents; Arsenic; Azacitidine; Chromosome Deletion; Chromosomes, Human, Pair 5; Cyclosporine; Cytarabine; Decitabine; Disease Progression; Enzyme Inhibitors; Erythrocyte Transfusion; Female; Hematinics; Humans; Hydroxyurea; Immunologic Factors; Lenalidomide; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Recurrence; Retreatment; Retrospective Studies; Risk Factors; Survival Rate; Thalidomide; Treatment Failure; Tretinoin; Valproic Acid

2017
Characteristics and Management of Autoimmune Bullous Disease in Psoriasis Patients.
    Annals of the Academy of Medicine, Singapore, 2019, Volume: 48, Issue:9

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Aged, 80 and over; Autoimmune Diseases; Cyclosporine; Disease Management; Enzyme Inhibitors; Female; Glucocorticoids; Humans; Hydroxyurea; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Mycophenolic Acid; Pemphigoid, Bullous; Pemphigus; Psoriasis; Retrospective Studies; Ultraviolet Therapy

2019