hydroxyurea and camptothecin

hydroxyurea has been researched along with camptothecin in 68 studies

Research

Studies (68)

Timeframe	Studies, this research(%)	All Research%
pre-1990	12 (17.65)	18.7374
1990's	8 (11.76)	18.2507
2000's	19 (27.94)	29.6817
2010's	28 (41.18)	24.3611
2020's	1 (1.47)	2.80

Authors

Authors	Studies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Becker, Y	1
Asher, Y; Becker, Y	1
Boyse, EA; Goldstein, G; Hammerling, U; Storrie, B	1
Snapka, RM; Wani, MA	1
Covey, JM; Holm, C; Kerrigan, D; Pommier, Y	1
Crissman, HA; Tobey, RA	1
Bhuyan, BK; Fraser, TJ	1
Becker, Y; Ben-Zeev, A; Weinberg, E	1
Moertel, CG	1
Bosmann, HB	1
Homan, ER; Neil, GL	1
Bhuyan, BK; Fraser, TJ; Gray, LG; Kuentzel, SL; Neil, GL	1
Paparopoli, G; Sciarrino, E	1
Kato, M; Takada, S; Takayama, S	1
Berger, NA; Chatterjee, S; Cheng, MF	1
Akiyama, Y; Furusho, K; Kataoka, A; Koishi, S; Kubota, M; Lin, YW; Sawada, M; Usami, I; Watanabe, Ki	1
Akiyama, Y; Furusho, K; Kataoka, A; Kitoh, T; Koishi, S; Kubota, M; Lin, YW; Sawada, M; Usami, I; Watanabe, K	1
Avalos-Diaz, E; Herrera-Esparza, R; Lopez-Swiderski, A; Ramirez-Santoyo, R	1
Durka, S; Hueber, A; Weller, M	1
Hunter, P; Ikegami, R; Yager, TD	1
Walworth, NC; Wan, S	1
Mankouri, HW; Morgan, A	1
Franchitto, A; Mosesso, P; Palitti, F; Pichierri, P	1
Akagi, T; Higuchi, S; Inoue, K; Ishizaki, T; Kage, Y; Makinosumi, T; Ohdo, S; Taguchi, Y; Ushinohama, K; Yamauchi, A; Yukawa, E	1
Franchitto, A; Pichierri, P; Rosselli, F	1
André, T; Artru, P; Carola, E; de Gramont, A; Gilles-Amar, V; Krulik, M; Louvet, C; Mabro, M	1
Barber, LJ; Carr, AM; Hartley, JA; Lambert, S; Mason, SJ; McHugh, PJ; Pearce, JA	1
Al-Amodi, H; McInerny, CJ; Nakamura, T; Shimoda, C; Yoshida, SH	1
Blank, A; Bobola, MS; D Kolstoe, D; Gold, B; Loeb, LA; Meade, EH; Rabinovitch, PS; Silber, JR; Varadarajan, S	1
Bissler, JJ; Dixon, K; Lu, L; Robison, JG	1
Bartek, J; Dziegielewski, J; Hansen, LT; Helleday, T; Lundin, C; Syljuåsen, RG; Sørensen, CS	1
Choi, VW; McCarty, DM; Samulski, RJ	1
Chmura, SJ; Haraf, DJ; Kao, J; Milano, MT; Salama, JK; Stenson, KM; Vokes, EE; Witt, ME	1
Asahina, K; Ichijima, Y; Okita, N; Sakasai, R; Shibata, A; Shinohe, K; Teraoka, H	1
Han, J; Horazdovsky, B; Xu, RM; Zhang, K; Zhang, Z; Zhou, H	1
Adachi, N; Koyama, H; Nomura, Y	1
Jin, W; Liu, H; Otta, SK; Plon, SE; Wang, LL; Zhang, Y	1
Doré, AS; Ho, JC; Kilkenny, ML; Nestoras, K; Pearl, LH; Roe, SM; Watts, FZ	1
Baulch, JE; Dziegielewski, J; Goetz, W; Grdina, DJ; Morgan, WF; Murley, JS	1
Anderson, S; Baker, SP; Grant, PA; Hunt, DF; Phillips, J; Qiu, Q; Shabanowitz, J; Smith, MM; Yates, JR	1
Blair, EA; Haraf, DJ; Pederson, AW; Salama, JK; Stenson, KM; Vokes, EE; Witt, ME	1
Du, LL; Han, TX; Peng, X; Xu, XY; Zhang, MJ	1
Emond, MJ; Lauper, JM; Mao, FJ; Monnat, RJ; Sidorova, JM	1
Bacal, J; Dorn, J; Kaiser, GS; Lee, EH; Lisby, M; Maddox, P; Pasero, P; St-Hilaire, E; Tsao, S; Verreault, A; Wurtele, H	1
Bohr, VA; Frøhlich, R; Patro, BS; Stevnsner, T	1
Chung, I; Eastman, A; Garner, KM; Montano, R; Parry, D	1
Aslanian, A; de Bruin, RA; Guaderrama, M; Ideker, T; Kalashnikova, TI; Kuo, D; Smolka, MB; Thai, K; Travesa, A; Wittenberg, C; Yates, JR	1
Jiang, G; Wu, X; Zou, Y	1
Travesa, A; Wittenberg, C	1
Eckert-Boulet, N; Eléouët, M; Gallina, I; Game, J; Germann, SM; Hamou, W; Lisby, M; Mathiasen, DP; Thodberg, S	1
Atsumi, Y; Fujimori, H; Inase, A; Kanno, M; Masutani, M; Nakagama, H; Osawa, T; Sakasai, R; Saya, H; Sugihara, E; Tashiro, F; Teraoka, H; Yoshioka, K	1
Chen, CH; Chen, WS; Cheng, AN; Fan, CC; Huang, TS; Jiang, SS; Kuo, CY; Lee, AY; Lee, CC; Liu, YL; Lo, YK; Wang, TY	1
Belfield, C; Kitamura, K; Queenan, C; Rao, H; Walworth, NC	1
Borowiec, JA; Chowdhury, D; Fitzgerald, M; Kim, JH; Murphy, AK; Rabinowitsch, AI; Ro, T; Schildkraut, CL	1
Kusakabe, T; Lee, JM; Mon, H; Shiotsuki, T; Sugahara, R	1
Aguilera, A; García-Rodríguez, N; Stuckey, R; Wellinger, RE	1
Wu, CS; Zou, L	1
Bernstein, KA; Godin, SK; Herken, BW; Lee, AG; Mihalevic, MJ; Resnick, MA; Sobol, RW; Westmoreland, JW; Yu, Z; Zhang, Z	1
Bi, X; Kath, M; Siler, J; Wong, C; Xia, B	1
Korbel, JO; Mardin, BR; Onishi-Seebacher, M; Segura-Wang, M; Stütz, AM	1
Chen, G; Chen, J; Li, T; Liu, W; Liu, X; Qiao, Y; Shi, X; Shi, Y; Sun, Y; Wan, J; Wang, F; Wang, H; Xie, H; Xie, T; Zeng, Q; Zhou, L	1
Ahmed, KM; Chakraborty, S; Charaka, V; Hambarde, S; Hunt, CR; Pandita, RK; Pandita, TK; Ramnarain, D; Singh, DK; Singh, M	1
Gu, S; Jin, L; Ma, J; Ni, X; Pan, Q; Wang, J; Xu, M; Zhen, N; Zhu, J	1
Gao, X; Ji, J; Li, M; Lv, J; Mao, W; Sun, C; Wang, J; Yang, W; Zhang, L; Zhao, Z	1
Gao, Y; Hua, Y; Mao, S; Shi, R; Song, S; Tian, B; Wang, L; Wang, Y; Xiao, Y; Xu, H; Xu, X; Zhao, Y	1

Reviews

1 review(s) available for hydroxyurea and camptothecin

Article	Year
Trends in research and development of antiviral substances. Israel journal of medical sciences, 1975, Volume: 11, Issue:11 Topics: Amanitins; Amantadine; Amino Acids; Antiviral Agents; Benzimidazoles; Camptothecin; Chemical Phenomena; Chemistry; Cystamine; Dactinomycin; Distamycins; DNA-Directed RNA Polymerases; Hydroxyurea; Interferon Inducers; Interferons; Methisazone; Nucleosides; Plicamycin; Polysaccharides; Research Design; Rhodanine; Rifamycins; Selenium; Silicon; Tungsten; Viruses; Zinc	1975

Article

Year

Trends in research and development of antiviral substances.

Israel journal of medical sciences, 1975, Volume: 11, Issue:11

Topics: Amanitins; Amantadine; Amino Acids; Antiviral Agents; Benzimidazoles; Camptothecin; Chemical Phenomena; Chemistry; Cystamine; Dactinomycin; Distamycins; DNA-Directed RNA Polymerases; Hydroxyurea; Interferon Inducers; Interferons; Methisazone; Nucleosides; Plicamycin; Polysaccharides; Research Design; Rhodanine; Rifamycins; Selenium; Silicon; Tungsten; Viruses; Zinc

1975

Trials

1 trial(s) available for hydroxyurea and camptothecin

Article	Year
Bimonthly leucovorin, infusion 5-fluorouracil, hydroxyurea, and irinotecan (FOLFIRI-2) for pretreated metastatic colorectal cancer. American journal of clinical oncology, 2003, Volume: 26, Issue:3 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Hydroxyurea; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Survival Analysis	2003

Article

Year

Bimonthly leucovorin, infusion 5-fluorouracil, hydroxyurea, and irinotecan (FOLFIRI-2) for pretreated metastatic colorectal cancer.

American journal of clinical oncology, 2003, Volume: 26, Issue:3

Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Hydroxyurea; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Survival Analysis

2003

Other Studies

66 other study(ies) available for hydroxyurea and camptothecin

Article	Year
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
In vitro synthesis of DNA in nuclei isolated from herpes simplex virus-infected cells, untreated and treated with metabolic inhibitors. Virology, 1975, Volume: 63, Issue:1 Topics: Adenine Nucleotides; Animals; Anti-Bacterial Agents; Camptothecin; Cell Line; Cell Nucleus; Centrifugation, Density Gradient; Culture Media; Cytarabine; Cytosine Nucleotides; Deoxyadenosines; DNA; DNA, Viral; Guanine Nucleotides; Haplorhini; Hydroxyurea; Kidney; Magnesium; Simplexvirus; Sucrose; Thymine Nucleotides; Tritium; Virus Replication	1975
Differentiation of thymocytes: evidence that induction of the surface phenotype requires transcription and translation. Journal of immunology (Baltimore, Md. : 1950), 1976, Volume: 116, Issue:5 Topics: Animals; Camptothecin; Cell Differentiation; Cycloheximide; Cytarabine; Dactinomycin; Deoxyadenosines; DNA; Hydroxyurea; In Vitro Techniques; Macromolecular Substances; Mice; Mice, Inbred Strains; Phenotype; Protein Biosynthesis; Protein Precursors; Puromycin; RNA; T-Lymphocytes; Thymus Extracts; Transcription, Genetic	1976
Drug-induced loss of unstably amplified genes. Cancer investigation, 1990, Volume: 8, Issue:6 Topics: Camptothecin; Dose-Response Relationship, Drug; Drug Resistance; Eflornithine; Gene Amplification; Guanazole; Hydroxyurea; Methotrexate; Proflavine; Tetrahydrofolate Dehydrogenase	1990
Differential requirement of DNA replication for the cytotoxicity of DNA topoisomerase I and II inhibitors in Chinese hamster DC3F cells. Cancer research, 1989, Nov-15, Volume: 49, Issue:22 Topics: Amsacrine; Animals; Aphidicolin; Camptothecin; Cell Line; Cell Survival; Cricetinae; Cricetulus; Diterpenes; DNA Replication; Etoposide; Hydroxyurea; Kinetics; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors	1989
Use of flow microfluorometry in detailed analysis of effects of chemical agents on cell cycle progression. Cancer research, 1972, Volume: 32, Issue:12 Topics: Animals; Antineoplastic Agents; Autoradiography; Bleomycin; Camptothecin; Cell Division; Cell Line; Cricetinae; Cytarabine; DNA Replication; Fluorometry; Hydroxyurea; Mitosis; Thymidine; Time Factors; Tritium	1972
Frozen DON cells as a source for a cell cycle assay of antitumor agents. Experimental cell research, 1974, Volume: 83, Issue:1 Topics: Alkaloids; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Biological Assay; Camptothecin; Carbazoles; Cell Division; Cell Line; Cell Survival; Cricetinae; Cryoprotective Agents; Cytarabine; Cytological Techniques; Dactinomycin; Dimethyl Sulfoxide; Floxuridine; Formates; Freezing; Glycerol; Hydroxyurea; Lung; Mitosis; Proteins; Pyridines; Ribonucleosides; Thiosemicarbazones; Time Factors	1974
Isolation of herpes simplex virus DNA from virus particles and infected cells by electrophoresis in polyacrylamide gels. The Journal of general virology, 1974, Volume: 25, Issue:1 Topics: Animals; Camptothecin; Carbon Radioisotopes; Cell Fractionation; Cell Line; Cell Nucleus; Centrifugation, Density Gradient; Cytarabine; Cytoplasm; DNA; DNA Replication; DNA, Viral; Electrophoresis, Polyacrylamide Gel; Haplorhini; Hydroxyurea; Kidney; Molecular Weight; Simplexvirus; Thymidine; Tritium	1974
Cancer of the gastrointestinal tract. Chemotherapy. JAMA, 1974, Jun-03, Volume: 228, Issue:10 Topics: Antineoplastic Agents; Camptothecin; Carmustine; Cyclohexanes; Cyclophosphamide; Drug Therapy, Combination; Fluorometholone; Fluorouracil; Humans; Hydroxyurea; Mitomycins; Nitrosourea Compounds; Remission, Spontaneous; Stomach Neoplasms; Streptonigrin; Time Factors	1974
Antineoplastic drug activity in the mitotic cycle--effects of six agents on macromolecular synthesis in synchronous mammalian leukemic cells. Biochemical pharmacology, 1972, Jul-15, Volume: 21, Issue:14 Topics: Animals; Antineoplastic Agents; Asparaginase; Azaserine; Camptothecin; Culture Media; DNA, Neoplasm; Ethidium; Fucose; Glucosamine; Glycoproteins; Hydroxyurea; Leucine; Leukemia, Experimental; Mice; Mitosis; Neoplasm Proteins; RNA, Neoplasm; Thymidine; Time Factors; Tritium; Uridine	1972
The effect of dose interval on the survival of L1210 leukemic mice treated with DNA synthesis inhibitors. Cancer research, 1973, Volume: 33, Issue:4 Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Division; Cell Survival; Cytarabine; DNA, Neoplasm; Formates; Hydroxyurea; Leukemia L1210; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Pyridines; Thiosemicarbazones; Thymidine; Time Factors	1973
Cell-kill kinetics of several S-phase-specific drugs. Cancer research, 1973, Volume: 33, Issue:4 Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Division; Cell Line; Cell Survival; Cricetinae; Cytarabine; DNA, Neoplasm; Formates; Hydroxyurea; Kinetics; Leukemia L1210; Lung; Mice; Neoplasms, Experimental; Pyridines; Thiosemicarbazones; Time Factors	1973
[Recent diagnostic and therapeutic acquisitions in malignant melanoma]. Il Cancro, 1974, Volume: 27, Issue:1 Topics: Antineoplastic Agents; Camptothecin; Chloroquine; Colchicine; Humans; Hydroxyurea; Imidazoles; Immunotherapy; Iodine Radioisotopes; Melanoma; Nitrosourea Compounds; Radionuclide Imaging; Triazenes	1974
Comparison of lesions induced by intra-articular injections of quinolones and compounds damaging cartilage components in rat femoral condyles. Journal of toxicology and environmental health, 1994, Volume: 42, Issue:1 Topics: Administration, Oral; Animals; Bleomycin; Camptothecin; Cartilage, Articular; Chondroitin Lyases; Ciprofloxacin; Collagenases; Cycloheximide; Ethylmaleimide; Etoposide; Fluorescent Dyes; Hydroxyurea; Injections, Intra-Articular; Iodoacetates; Iodoacetic Acid; Irinotecan; Levofloxacin; Male; Ofloxacin; Papain; Rats; Rats, Sprague-Dawley; Rhodamines; Topoisomerase I Inhibitors	1994
Schedule-dependent cytotoxicity of topotecan alone and in combination chemotherapy regimens. Oncology research, 1994, Volume: 6, Issue:6 Topics: Alkylating Agents; Animals; Antineoplastic Combined Chemotherapy Protocols; Aphidicolin; Camptothecin; Carmustine; Cell Cycle; Cell Death; Cell Line; Cisplatin; Cricetinae; Cricetulus; DNA Damage; DNA Repair; DNA, Neoplasm; Doxorubicin; Drug Synergism; Etoposide; Fibroblasts; Hydroxyurea; Lung; Melphalan; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Topotecan	1994
Apoptosis-resistant phenotype selected by alternating exposure to camptothecin and etoposide. Experimental cell research, 1997, Aug-25, Volume: 235, Issue:1 Topics: Antineoplastic Agents; Apoptosis; Arabinofuranosylcytosine Triphosphate; ATP Binding Cassette Transporter, Subfamily B, Member 1; bcl-X Protein; Calcimycin; Camptothecin; Clone Cells; Cycloheximide; Cytarabine; DNA Fragmentation; Drug Resistance, Neoplasm; Etoposide; HL-60 Cells; Humans; Hydroxyurea; Kinetics; Nucleosomes; Phenotype; Proto-Oncogene Proteins c-bcl-2; Ultraviolet Rays	1997
NADH dehydrogenase deficiency in an apoptosis-resistant mutant isolated from a human HL-60 leukemia cell line. Cancer research, 1997, Dec-01, Volume: 57, Issue:23 Topics: Antineoplastic Agents; Apoptosis; Calcimycin; Camptothecin; Cell Division; Clone Cells; Cloning, Molecular; Cytarabine; Deoxyglucose; Etoposide; Glucose; HL-60 Cells; Humans; Hydroxyurea; Macromolecular Substances; Mitochondria; Mutagenesis; NADH Dehydrogenase; Transcription, Genetic; Ultraviolet Rays	1997
The expression and localization of Scl-70/DNA topoisomerase I vary throughout the cell cycle. Revue du rhumatisme (English ed.), 1998, Volume: 65, Issue:3 Topics: Antineoplastic Agents, Phytogenic; Autoantigens; Blotting, Western; Camptothecin; Cell Cycle; Cell Division; DNA Replication; DNA Topoisomerases, Type I; Fluorescent Antibody Technique, Indirect; Humans; Hydroxyurea; Mitotic Index; Nuclear Proteins; Nucleic Acid Synthesis Inhibitors; S Phase; Scleroderma, Systemic; Topoisomerase I Inhibitors; Tumor Cells, Cultured	1998
CD95-mediated apoptosis: no variation in cellular sensitivity during cell cycle progression. FEBS letters, 1998, Aug-07, Volume: 432, Issue:3 Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Aphidicolin; Apoptosis; Camptothecin; Cell Cycle; Cell Death; Cisplatin; Culture Media, Serum-Free; Doxorubicin; Enzyme Inhibitors; Fas Ligand Protein; fas Receptor; Gene Expression; HeLa Cells; Humans; Hydroxyurea; Jurkat Cells; Membrane Glycoproteins; Nimustine; Nocodazole; Paclitaxel; Sensitivity and Specificity; Teniposide; Tumor Cells, Cultured; Vincristine	1998
Developmental activation of the capability to undergo checkpoint-induced apoptosis in the early zebrafish embryo. Developmental biology, 1999, May-15, Volume: 209, Issue:2 Topics: Animals; Aphidicolin; Apoptosis; Blastocyst; Camptothecin; Caspases; Cell Cycle; Cell Division; Cell Lineage; Cell Membrane; Cell Nucleus; Cysteine Proteinase Inhibitors; DNA Damage; DNA Fragmentation; DNA Replication; Embryo, Nonmammalian; Enzyme Inhibitors; Gastrula; Hydroxyurea; In Situ Nick-End Labeling; Isoenzymes; Mammals; Microscopy, Confocal; Nucleic Acid Synthesis Inhibitors; Oligopeptides; Species Specificity; Stress, Physiological; Topoisomerase I Inhibitors; Xenopus laevis; Zebrafish	1999
A novel genetic screen identifies checkpoint-defective alleles of Schizosaccharomyces pombe chk1. Current genetics, 2001, Volume: 38, Issue:6 Topics: Alleles; Amino Acid Sequence; Camptothecin; Cell Cycle Proteins; Checkpoint Kinase 1; Conserved Sequence; DNA Damage; DNA Replication; Genes, cdc; Genes, Fungal; Genotype; Hydroxyurea; Molecular Sequence Data; Mutation; Nuclear Proteins; Phenotype; Phosphorylation; Point Mutation; Protein Kinases; Protein-Tyrosine Kinases; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Ultraviolet Rays	2001
The DNA helicase activity of yeast Sgs1p is essential for normal lifespan but not for resistance to topoisomerase inhibitors. Mechanisms of ageing and development, 2001, Volume: 122, Issue:11 Topics: 4-Nitroquinoline-1-oxide; Camptothecin; Cycloheximide; DNA Helicases; Drug Resistance, Microbial; Ethylmaleimide; Hydroxyurea; Methyl Methanesulfonate; Mitoxantrone; Mutagenesis; RecQ Helicases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Topoisomerase I Inhibitors	2001
Werner's syndrome protein is required for correct recovery after replication arrest and DNA damage induced in S-phase of cell cycle. Molecular biology of the cell, 2001, Volume: 12, Issue:8 Topics: Apoptosis; Camptothecin; Cells, Cultured; Comet Assay; DNA Damage; DNA Helicases; DNA Nucleotidyltransferases; DNA Repair; DNA Replication; DNA-Binding Proteins; Enzyme Inhibitors; Exodeoxyribonucleases; Fibroblasts; Flow Cytometry; Humans; Hydroxyurea; Immunohistochemistry; Nucleic Acid Synthesis Inhibitors; Rad51 Recombinase; RecQ Helicases; S Phase; Werner Syndrome; Werner Syndrome Helicase	2001
Cell kinetics-dependent antitumor effect of irinotecan hydrochloride induced by the synchronizing effect of hydroxyurea: cell kinetics and dosing time. Life sciences, 2003, Jan-24, Volume: 72, Issue:10 Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Body Weight; Bone Marrow Cells; Camptothecin; Cell Cycle; DNA; Esterases; Hydroxyurea; Irinotecan; Male; Mice; Mice, Inbred ICR; Neoplasm Transplantation; Sarcoma 180	2003
Werner's syndrome protein is phosphorylated in an ATR/ATM-dependent manner following replication arrest and DNA damage induced during the S phase of the cell cycle. Oncogene, 2003, Mar-13, Volume: 22, Issue:10 Topics: Ataxia Telangiectasia Mutated Proteins; Camptothecin; Cell Cycle Proteins; Cell Nucleus Structures; Cells, Cultured; DNA Damage; DNA Helicases; DNA Replication; DNA-Binding Proteins; Enzyme Inhibitors; Exodeoxyribonucleases; Fibroblasts; Humans; Hydroxyurea; Lymphocytes; Phosphorylation; Protein Serine-Threonine Kinases; RecQ Helicases; S Phase; Tumor Suppressor Proteins; Werner Syndrome; Werner Syndrome Helicase	2003
Schizosaccharomyces pombe checkpoint response to DNA interstrand cross-links. Molecular and cellular biology, 2003, Volume: 23, Issue:13 Topics: Camptothecin; Cell Survival; Checkpoint Kinase 2; Cisplatin; Cross-Linking Reagents; DNA; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Enzyme Inhibitors; G2 Phase; Hydroxyurea; Mitomycin; Nucleic Acid Synthesis Inhibitors; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Radiation-Sensitizing Agents; Recombination, Genetic; S Phase; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Temperature; Time Factors	2003
The Schizosaccharomyces pombe cdt2(+) gene, a target of G1-S phase-specific transcription factor complex DSC1, is required for mitotic and premeiotic DNA replication. Genetics, 2003, Volume: 164, Issue:3 Topics: 4-Nitroquinoline-1-oxide; Amino Acid Sequence; Camptothecin; DNA Primers; DNA Replication; Electrophoresis, Gel, Pulsed-Field; Electrophoretic Mobility Shift Assay; Flow Cytometry; Gene Expression; Hydroxyurea; Immunoblotting; Microscopy, Fluorescence; Mitosis; Molecular Sequence Data; Mutagenesis; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Sequence Analysis, DNA; Temperature; Transcription Factors	2003
The Werner syndrome protein confers resistance to the DNA lesions N3-methyladenine and O6-methylguanine: implications for WRN function. DNA repair, 2004, Jun-03, Volume: 3, Issue:6 Topics: 4-Nitroquinoline-1-oxide; Adenine; Alkylating Agents; Antineoplastic Agents; Apoptosis; Camptothecin; Carcinogens; Cells, Cultured; DNA Damage; DNA Helicases; DNA Replication; Drug Resistance; Exodeoxyribonucleases; Fibroblasts; Glioma; Guanine; Humans; Hydroxyurea; Netropsin; O(6)-Methylguanine-DNA Methyltransferase; Oligonucleotides, Antisense; RecQ Helicases; Werner Syndrome; Werner Syndrome Helicase	2004
DNA lesion-specific co-localization of the Mre11/Rad50/Nbs1 (MRN) complex and replication protein A (RPA) to repair foci. The Journal of biological chemistry, 2005, Apr-01, Volume: 280, Issue:13 Topics: Acid Anhydride Hydrolases; Blotting, Western; Camptothecin; Cations; Cell Cycle Proteins; Cell Nucleus; Comet Assay; DNA; DNA Damage; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; DNA, Single-Stranded; Etoposide; HeLa Cells; Humans; Hydroxyurea; Macromolecular Substances; Microscopy, Fluorescence; Mitomycin; Models, Biological; MRE11 Homologue Protein; Multiprotein Complexes; Nuclear Proteins; Phosphorylation; Protein Binding; Replication Protein A; Time Factors	2005
The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair. Nature cell biology, 2005, Volume: 7, Issue:2 Topics: Animals; Camptothecin; Checkpoint Kinase 1; Cricetinae; DNA; DNA Damage; DNA Repair; DNA-Binding Proteins; Humans; Hydroxyurea; Protein Kinases; Rad51 Recombinase; Recombination, Genetic; Signal Transduction	2005
Effects of adeno-associated virus DNA hairpin structure on recombination. Journal of virology, 2005, Volume: 79, Issue:11 Topics: Aphidicolin; Base Sequence; Camptothecin; Dependovirus; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA, Circular; DNA, Viral; Etoposide; Genes, Reporter; Genetic Vectors; Genome, Viral; HeLa Cells; Humans; Hydroxyurea; Nucleic Acid Conformation; Recombination, Genetic; Terminal Repeat Sequences	2005
Long-term outcome of concurrent chemotherapy and reirradiation for recurrent and second primary head-and-neck squamous cell carcinoma. International journal of radiation oncology, biology, physics, 2006, Feb-01, Volume: 64, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Camptothecin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Gemcitabine; Head and Neck Neoplasms; Humans; Hydroxyurea; Irinotecan; Male; Mandibular Diseases; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Osteoradionecrosis; Paclitaxel; Prognosis; Radiotherapy Dosage; Treatment Failure; Treatment Outcome	2006
Differential involvement of phosphatidylinositol 3-kinase-related protein kinases in hyperphosphorylation of replication protein A2 in response to replication-mediated DNA double-strand breaks. Genes to cells : devoted to molecular & cellular mechanisms, 2006, Volume: 11, Issue:3 Topics: Ataxia Telangiectasia Mutated Proteins; Camptothecin; Cell Cycle Proteins; Cells, Cultured; DNA; DNA Damage; DNA Replication; DNA-Activated Protein Kinase; DNA-Binding Proteins; Enzyme Inhibitors; Humans; Hydroxyurea; Kidney; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Replication Protein A; RNA, Small Interfering; Tumor Suppressor Proteins	2006
Rtt109 acetylates histone H3 lysine 56 and functions in DNA replication. Science (New York, N.Y.), 2007, Feb-02, Volume: 315, Issue:5812 Topics: Acetylation; Amino Acid Sequence; Camptothecin; Catalytic Domain; Chromosome Breakage; DNA Damage; DNA Replication; Histone Acetyltransferases; Histones; Hydroxyurea; Lysine; Methyl Methanesulfonate; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutagens; Mutation; Recombinant Proteins; S Phase; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid	2007
Human Mus81 and FANCB independently contribute to repair of DNA damage during replication. Genes to cells : devoted to molecular & cellular mechanisms, 2007, Volume: 12, Issue:10 Topics: Camptothecin; Cell Proliferation; Cross-Linking Reagents; DNA; DNA Damage; DNA Replication; DNA-Binding Proteins; Endonucleases; Fanconi Anemia Complementation Group Proteins; HeLa Cells; Humans; Hydroxyurea; Models, Biological; Mutation; Rad51 Recombinase; Sister Chromatid Exchange	2007
Sensitivity of RECQL4-deficient fibroblasts from Rothmund-Thomson syndrome patients to genotoxic agents. Human genetics, 2008, Volume: 123, Issue:6 Topics: 4-Nitroquinoline-1-oxide; Antineoplastic Agents; Camptothecin; Cisplatin; DNA Damage; DNA Replication; Doxorubicin; Drug Evaluation, Preclinical; Drug Resistance; Fibroblasts; Humans; Hydroxyurea; Mutagenicity Tests; Mutagens; Polymorphism, Single Nucleotide; Radiation, Ionizing; RecQ Helicases; Rothmund-Thomson Syndrome; Ultraviolet Rays	2008
Structural and functional analysis of the Crb2-BRCT2 domain reveals distinct roles in checkpoint signaling and DNA damage repair. Genes & development, 2008, Aug-01, Volume: 22, Issue:15 Topics: Amino Acid Sequence; Camptothecin; Cell Cycle; Cell Cycle Proteins; Crystallography, X-Ray; Dimerization; DNA Damage; DNA Repair; Dose-Response Relationship, Radiation; Histidine; Hydroxyurea; Infrared Rays; Models, Molecular; Molecular Sequence Data; Mutation; Nuclear Proteins; Protein Structure, Tertiary; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Sequence Homology, Amino Acid; Signal Transduction; Ultraviolet Rays	2008
Amifostine metabolite WR-1065 disrupts homologous recombination in mammalian cells. Radiation research, 2010, Volume: 173, Issue:2 Topics: Amifostine; Animals; Camptothecin; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; DNA-Binding Proteins; Genomic Instability; Humans; Hydroxyurea; Mercaptoethylamines; Rad51 Recombinase; Radiation-Protective Agents; Reactive Oxygen Species; Recombination, Genetic; RNA Interference	2010
Histone H3 Thr 45 phosphorylation is a replication-associated post-translational modification in S. cerevisiae. Nature cell biology, 2010, Volume: 12, Issue:3 Topics: Acetylation; Amino Acid Substitution; Camptothecin; Cell Cycle; Cell Cycle Proteins; Cell Proliferation; DNA Replication; Histones; Hydroxyurea; Intracellular Signaling Peptides and Proteins; Lysine; Mutation; Nocodazole; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Recombinant Proteins; S Phase; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Threonine	2010
Chemoradiotherapy for locoregionally advanced squamous cell carcinoma of the base of tongue. Head & neck, 2010, Volume: 32, Issue:11 Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Disease-Free Survival; Female; Fluorouracil; Humans; Hydroxyurea; Interferon alpha-2; Interferon-alpha; Irinotecan; Leucovorin; Male; Middle Aged; Neck Dissection; Paclitaxel; Radiotherapy Dosage; Radiotherapy, Adjuvant; Radiotherapy, Intensity-Modulated; Recombinant Proteins; Tongue Neoplasms	2010
Global fitness profiling of fission yeast deletion strains by barcode sequencing. Genome biology, 2010, Volume: 11, Issue:6 Topics: Base Sequence; Camptothecin; Cluster Analysis; Culture Media; Electronic Data Processing; Gene Deletion; Gene Silencing; Genetic Fitness; Haploidy; Hydroxyurea; Microtubules; Mutagens; Reproducibility of Results; Schizosaccharomyces; Sequence Analysis, DNA; Thiabendazole	2010
The human WRN and BLM RecQ helicases differentially regulate cell proliferation and survival after chemotherapeutic DNA damage. Cancer research, 2010, Aug-15, Volume: 70, Issue:16 Topics: Antineoplastic Agents; Bone Neoplasms; Bromodeoxyuridine; Camptothecin; Cell Growth Processes; Cell Line, Tumor; Cisplatin; DNA Damage; Exodeoxyribonucleases; Fibroblasts; Fluorouracil; Histones; Humans; Hydroxyurea; Osteosarcoma; RecQ Helicases; Werner Syndrome Helicase	2010
Histone H3 lysine 56 acetylation and the response to DNA replication fork damage. Molecular and cellular biology, 2012, Volume: 32, Issue:1 Topics: Acetylation; Antineoplastic Agents; Camptothecin; DNA Damage; DNA Repair; DNA Replication; DNA, Fungal; Histones; Hydroxyurea; Lysine; Methyl Methanesulfonate; Mutagens; Mutation; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins	2012
WRN helicase regulates the ATR-CHK1-induced S-phase checkpoint pathway in response to topoisomerase-I-DNA covalent complexes. Journal of cell science, 2011, Dec-01, Volume: 124, Issue:Pt 23 Topics: Ataxia Telangiectasia Mutated Proteins; Camptothecin; Cell Cycle Proteins; Cell Line, Tumor; Checkpoint Kinase 1; Chromatin; Chromatin Immunoprecipitation; DNA Damage; DNA Replication; DNA, Single-Stranded; Exodeoxyribonucleases; Gene Expression Regulation, Enzymologic; Gene Knockdown Techniques; Genomic Instability; Humans; Hydroxyurea; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; RecQ Helicases; RNA, Small Interfering; S Phase Cell Cycle Checkpoints; Topoisomerase I Inhibitors; Werner Syndrome Helicase	2011
Preclinical development of the novel Chk1 inhibitor SCH900776 in combination with DNA-damaging agents and antimetabolites. Molecular cancer therapeutics, 2012, Volume: 11, Issue:2 Topics: Antimetabolites; Antineoplastic Agents; Blotting, Western; Camptothecin; Cell Cycle Checkpoints; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Survival; Checkpoint Kinase 1; Cytarabine; Deoxycytidine; DNA Breaks, Double-Stranded; DNA Damage; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Flow Cytometry; Gemcitabine; Humans; Hydroxyurea; Irinotecan; Molecular Structure; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Pyrazoles; Pyrimidines; Staurosporine	2012
DNA replication stress differentially regulates G1/S genes via Rad53-dependent inactivation of Nrm1. The EMBO journal, 2012, Apr-04, Volume: 31, Issue:7 Topics: Camptothecin; Cell Cycle Proteins; Checkpoint Kinase 2; DNA Damage; DNA Replication; G1 Phase; Gene Expression Regulation, Fungal; Hydroxyurea; Methyl Methanesulfonate; Mutagens; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Repressor Proteins; S Phase; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transcription Factors	2012
Replication-mediated disassociation of replication protein A-XPA complex upon DNA damage: implications for RPA handing off. Cell biology international, 2012, Aug-01, Volume: 36, Issue:8 Topics: Camptothecin; Cell Cycle Checkpoints; Cell Line, Tumor; DNA; DNA Damage; DNA Repair; DNA Replication; DNA, Single-Stranded; Down-Regulation; Humans; Hydroxyurea; Phosphorylation; Protein Binding; Replication Protein A; Ultraviolet Rays; Xeroderma Pigmentosum Group A Protein	2012
Turned on by genotoxic stress. Cell cycle (Georgetown, Tex.), 2012, Sep-01, Volume: 11, Issue:17 Topics: Camptothecin; Cell Cycle; Cell Cycle Proteins; Checkpoint Kinase 2; DNA Damage; DNA Replication; Gene Expression Regulation, Fungal; Genes, cdc; Hydroxyurea; Methyl Methanesulfonate; Phosphorylation; Protein Serine-Threonine Kinases; Repressor Proteins; Saccharomyces cerevisiae Proteins; Saccharomycetales	2012
Physical mapping and cloning of RAD56. Gene, 2013, Apr-25, Volume: 519, Issue:1 Topics: Acetylation; Bleomycin; Camptothecin; Chromosome Mapping; Cloning, Molecular; DNA Damage; DNA Repair; DNA, Fungal; Hydroxyurea; Methyl Methanesulfonate; Mutation; N-Terminal Acetyltransferase B; Phenotype; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Analysis, DNA; X-Rays	2013
The Arf/p53 protein module, which induces apoptosis, down-regulates histone H2AX to allow normal cells to survive in the presence of anti-cancer drugs. The Journal of biological chemistry, 2013, May-10, Volume: 288, Issue:19 Topics: Animals; Antineoplastic Agents; Apoptosis; Camptothecin; Cell Shape; Cells, Cultured; Cellular Senescence; Cisplatin; Cyclin-Dependent Kinase Inhibitor p16; DNA Damage; DNA Replication; Down-Regulation; Doxorubicin; Drug Resistance, Neoplasm; Gene Knockdown Techniques; Histones; Humans; Hydroxyurea; Mice; Mice, Knockout; Mutation; Phenanthrenes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Tumor Suppressor Protein p53	2013
Increased Cdc7 expression is a marker of oral squamous cell carcinoma and overexpression of Cdc7 contributes to the resistance to DNA-damaging agents. Cancer letters, 2013, Sep-01, Volume: 337, Issue:2 Topics: Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Camptothecin; Carcinoma, Squamous Cell; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Chi-Square Distribution; DNA Damage; Drug Resistance, Neoplasm; Female; Humans; Hydroxyurea; Immunohistochemistry; Kaplan-Meier Estimate; Male; Mouth Neoplasms; Multivariate Analysis; Prognosis; Proportional Hazards Models; Protein Serine-Threonine Kinases; Radiation Tolerance; RNA Interference; Survival Rate; Time Factors; Transfection; Ultraviolet Rays; Up-Regulation	2013
The oxidative stress responsive transcription factor Pap1 confers DNA damage resistance on checkpoint-deficient fission yeast cells. PloS one, 2014, Volume: 9, Issue:2 Topics: Basic-Leucine Zipper Transcription Factors; Camptothecin; Cell Nucleus; Checkpoint Kinase 1; DNA Damage; DNA Ligases; Hydroxyurea; Microscopy, Fluorescence; Oxidative Stress; Pancreatitis-Associated Proteins; Protein Kinases; Schizosaccharomyces; Schizosaccharomyces pombe Proteins	2014
Phosphorylated RPA recruits PALB2 to stalled DNA replication forks to facilitate fork recovery. The Journal of cell biology, 2014, Aug-18, Volume: 206, Issue:4 Topics: Ataxia Telangiectasia Mutated Proteins; BRCA2 Protein; Camptothecin; Cell Line, Tumor; Chromatin; Cyclin-Dependent Kinase 2; DNA Damage; DNA Repair; DNA Replication; DNA-Binding Proteins; DNA, Single-Stranded; Fanconi Anemia Complementation Group N Protein; Humans; Hydroxyurea; Multiprotein Complexes; Nuclear Proteins; Nucleic Acid Synthesis Inhibitors; Phosphoprotein Phosphatases; Phosphorylation; Poly(ADP-ribose) Polymerase Inhibitors; Replication Protein A; RNA Interference; RNA, Small Interfering; Topoisomerase I Inhibitors; Tumor Suppressor Proteins	2014
Differential contribution of the Fanconi anemia-related proteins to repair of several types of DNA damage in cultured silkworm cells. FEBS letters, 2014, Nov-03, Volume: 588, Issue:21 Topics: Animals; Bombyx; Camptothecin; Cells, Cultured; DNA Damage; DNA Helicases; DNA Repair; Fanconi Anemia Complementation Group D2 Protein; Histones; Homologous Recombination; Humans; Hydroxyurea; Mitomycin; Phosphorylation; Ubiquitination	2014
Role for RNA:DNA hybrids in origin-independent replication priming in a eukaryotic system. Proceedings of the National Academy of Sciences of the United States of America, 2015, May-05, Volume: 112, Issue:18 Topics: Bacterial Proteins; Camptothecin; Carcinogenesis; Cell Cycle; Cell Separation; Chromosomes; DNA; DNA Copy Number Variations; DNA Replication; DNA, Ribosomal; Electrophoresis, Gel, Two-Dimensional; Flow Cytometry; Gene Dosage; Genomic Instability; Humans; Hydroxyurea; Luminescent Proteins; Methyl Methanesulfonate; Mutation; Replication Origin; Ribonuclease H; RNA; Saccharomyces cerevisiae	2015
The SUMO (Small Ubiquitin-like Modifier) Ligase PIAS3 Primes ATR for Checkpoint Activation. The Journal of biological chemistry, 2016, Jan-01, Volume: 291, Issue:1 Topics: Adaptor Proteins, Signal Transducing; Ataxia Telangiectasia Mutated Proteins; Camptothecin; Cell Cycle Checkpoints; Cell Line; DNA Breaks, Double-Stranded; DNA Damage; DNA Replication; DNA-Binding Proteins; Enzyme Activation; Gene Knockdown Techniques; Humans; Hydroxyurea; Molecular Chaperones; Phosphorylation; Poly(ADP-ribose) Polymerases; Protein Binding; Protein Inhibitors of Activated STAT; RNA, Small Interfering; Sumoylation; Ultraviolet Rays	2016
The Shu complex promotes error-free tolerance of alkylation-induced base excision repair products. Nucleic acids research, 2016, 09-30, Volume: 44, Issue:17 Topics: Adenine; Alkylation; Camptothecin; Cisplatin; DNA Damage; DNA Polymerase beta; DNA Repair; DNA, Fungal; Epistasis, Genetic; Etoposide; Genes, Fungal; Genetic Loci; Homologous Recombination; Humans; Hydrogen Peroxide; Hydroxyurea; Methyl Methanesulfonate; Models, Biological; Mutation; Mutation Rate; Protein Binding; Radiation, Ionizing; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Ultraviolet Rays	2016
Cell cycle-dependent positive and negative functions of Fun30 chromatin remodeler in DNA damage response. DNA repair, 2017, Volume: 50 Topics: Camptothecin; Cell Cycle Checkpoints; Cell Cycle Proteins; Chromatin Assembly and Disassembly; DNA Breaks, Double-Stranded; DNA Repair; DNA, Fungal; Hydroxyurea; Methyl Methanesulfonate; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Stress, Physiological; Transcription Factors	2017
Systematic Identification of Determinants for Single-Strand Annealing-Mediated Deletion Formation in G3 (Bethesda, Md.), 2017, 10-05, Volume: 7, Issue:10 Topics: Camptothecin; DNA Damage; DNA Repair; DNA-Binding Proteins; DNA, Fungal; DNA, Single-Stranded; Doxorubicin; Gene Expression Profiling; Genomic Instability; Hydroxyurea; Methyl Methanesulfonate; Mutagens; Mutation; Nucleic Acid Synthesis Inhibitors; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors	2017
ZNF830 mediates cancer chemoresistance through promoting homologous-recombination repair. Nucleic acids research, 2018, 02-16, Volume: 46, Issue:3 Topics: Animals; Antineoplastic Agents; Ataxia Telangiectasia Mutated Proteins; Binding Sites; Camptothecin; Carrier Proteins; Cell Line, Tumor; DNA Breaks, Double-Stranded; DNA, Neoplasm; Drug Resistance, Neoplasm; Endodeoxyribonucleases; Epithelial Cells; Female; Genomic Instability; Humans; Hydroxyurea; Kruppel-Like Transcription Factors; Lung Neoplasms; Mice; Mice, Nude; Nuclear Proteins; Osteoblasts; Phosphorylation; Protein Binding; Recombinational DNA Repair; Stomach Neoplasms; Survival Analysis; Xenograft Model Antitumor Assays	2018
MOF Suppresses Replication Stress and Contributes to Resolution of Stalled Replication Forks. Molecular and cellular biology, 2018, 03-15, Volume: 38, Issue:6 Topics: Antineoplastic Agents; Camptothecin; Cell Death; Cisplatin; DNA Damage; DNA Repair; DNA Replication; HeLa Cells; Histone Acetyltransferases; Homologous Recombination; Humans; Hydroxyurea; Neoplasms; S Phase	2018
Ginsenoside Rg1 impairs homologous recombination repair by targeting CtBP-interacting protein and sensitizes hepatoblastoma cells to DNA damage. Anti-cancer drugs, 2018, Volume: 29, Issue:8 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Carrier Proteins; Cell Growth Processes; Cell Line, Tumor; DNA Damage; Drug Synergism; Endodeoxyribonucleases; Ginsenosides; Hep G2 Cells; Hepatoblastoma; Humans; Hydroxyurea; Liver Neoplasms; Male; Mice; Mice, Nude; Mitomycin; Nuclear Proteins; Phthalazines; Piperazines; Random Allocation; Recombinational DNA Repair; Xenograft Model Antitumor Assays	2018
Berberine attenuates XRCC1-mediated base excision repair and sensitizes breast cancer cells to the chemotherapeutic drugs. Journal of cellular and molecular medicine, 2019, Volume: 23, Issue:10 Topics: Antineoplastic Agents; Berberine; Breast Neoplasms; Camptothecin; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cisplatin; DNA Breaks; DNA Repair; Down-Regulation; Female; Humans; Hydroxyurea; Neoplasm Proteins; Phthalazines; Piperazines; S Phase; X-ray Repair Cross Complementing Protein 1	2019
Succinylation at a key residue of FEN1 is involved in the DNA damage response to maintain genome stability. American journal of physiology. Cell physiology, 2020, 10-01, Volume: 319, Issue:4 Topics: Camptothecin; Cell Cycle Proteins; DNA Damage; DNA Repair; DNA Replication; Exonucleases; Flap Endonucleases; Genome, Human; Genomic Instability; Humans; Hydroxyurea; Mitomycin; Multiprotein Complexes; Proliferating Cell Nuclear Antigen; Protein Processing, Post-Translational; Succinic Acid; SUMO-1 Protein; Sumoylation; Ultraviolet Rays	2020