Compounds > hydroxyurea

hydroxyurea and 4-methyl-5-amino-1-formylisoquinoline thiosemicarbazone

hydroxyurea has been researched along with 4-methyl-5-amino-1-formylisoquinoline thiosemicarbazone in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19908 (88.89)18.7374
1990's1 (11.11)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Atkins, LM; Gale, GR; Meischen, SJ; Schwartz, P1
Rittberg, DA; Wright, JA1
Carter, GL; Cory, JG1
Bacon, PE; Brown, NC; Carter, GL; Cory, JG; Montgomery, JA; Sato, A1
Bacon, PE; Cory, JG; Sato, A1
Caras, IW; Eriksson, S; Jones, T; Martin, DW1
Cory, JG; Sato, A1
Cory, JG; Lasater, L; Sato, A1
Cory, AH; Cory, JG; He, AW1

Other Studies

9 other study(ies) available for hydroxyurea and 4-methyl-5-amino-1-formylisoquinoline thiosemicarbazone

ArticleYear
Schedule-dependency assessments of ribonucleoside diphosphate reductase inhibitors when used in combination with platinum compounds plus cyclophosphamide in the treatment of advanced L1210 leukemia.
    Cancer treatment reports, 1979, Volume: 63, Issue:3

    Topics: Animals; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combination; Guanazole; Hydroxyurea; Isoquinolines; Leukemia L1210; Mice; Platinum; Ribonucleoside Diphosphate Reductase; Ribonucleotide Reductases; Thiosemicarbazones

1979
Relationships between sensitivity to hydroxyurea and 4-methyl-5-amino-1-formylisoquinoline thiosemicarbazone (MAIO) and ribonucleotide reductase RNR2 mRNA levels in strains of Saccharomyces cerevisiae.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 1989, Volume: 67, Issue:7

    Topics: Blotting, Northern; Hydroxyurea; Isoquinolines; Ribonucleoside Diphosphate Reductase; Ribonucleotide Reductases; RNA, Fungal; RNA, Messenger; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins

1989
Cross-resistance patterns in hydroxyurea-resistant leukemia L1210 cells.
    Cancer research, 1988, Oct-15, Volume: 48, Issue:20

    Topics: Adenine; Animals; Cell Line; Drug Resistance; Electron Spin Resonance Spectroscopy; Guanidines; Hydroxyurea; Isoquinolines; Leukemia L1210; Pyrazoles; Ribonucleotide Reductases

1988
The utility of combinations of drugs directed at specific sites of the same target enzyme--ribonucleotide reductase as the model.
    Advances in enzyme regulation, 1985, Volume: 23

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Cells, Cultured; Deoxyadenosines; Deoxyguanosine; Hydroxyurea; Isoquinolines; Leukemia L1210; Models, Biological; Nucleic Acid Synthesis Inhibitors; Phosphorylases; Pyrazoles; Ribonucleoside Diphosphate Reductase; Ribonucleotide Reductases; Thymidine; Vidarabine

1985
Studies on the differential mechanisms of inhibition of ribonucleotide reductase by specific inhibitors of the non-heme iron subunit.
    Advances in enzyme regulation, 1984, Volume: 22

    Topics: Anaerobiosis; Animals; Catalase; Cell Division; Cells, Cultured; Deferoxamine; Guanazole; Humans; Hydroxyurea; Isoenzymes; Isoquinolines; Leukemia L1210; Peroxidase; Peroxidases; Pyrazoles; Quinolines; Ribonucleoside Diphosphate Reductase; Ribonucleotide Reductases; Triazoles

1984
Direct photoaffinity labeling of the catalytic site of mouse ribonucleotide reductase by CDP.
    The Journal of biological chemistry, 1983, Mar-10, Volume: 258, Issue:5

    Topics: Affinity Labels; Animals; Cytidine Diphosphate; Cytosine Nucleotides; Deoxyribonucleotides; Hydroxyurea; Isoquinolines; Kinetics; Lymphoma; Macromolecular Substances; Mice; Molecular Weight; Neoplasms, Experimental; Ribonucleotide Reductases; Ribonucleotides

1983
Evaluation of combinations of drugs that inhibit Ehrlich tumor cell ribonucleotide reductase.
    Cancer research, 1981, Volume: 41, Issue:5

    Topics: Aldehydes; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Deoxyadenine Nucleotides; Deoxyguanine Nucleotides; Drug Interactions; Drug Synergism; Edetic Acid; Hydroxyurea; Imidazoles; Inosine; Isoquinolines; Mice; Pyrazoles; Ribonucleotide Reductases; Thiosemicarbazones; Thymine Nucleotides

1981
Specific inhibition of the subunits of ribonucleotide reductase as a new approach to combination chemotherapy.
    Advances in enzyme regulation, 1980, Volume: 19

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Drug Interactions; Drug Synergism; Female; Guanazole; Hydroxyurea; Iron Chelating Agents; Isoquinolines; Mice; Pyrazoles; Ribonucleoside Diphosphate Reductase; Ribonucleotide Reductases; Thiosemicarbazones

1980
Multifactorial mechanisms of drug resistance in tumor cell populations selected for resistance to specific chemotherapeutic agents.
    Advances in enzyme regulation, 1998, Volume: 38

    Topics: Animals; Antineoplastic Agents; Cell Division; Deoxyadenosines; Drug Resistance; Enzyme Inhibitors; Humans; Hydroxyurea; Isoquinolines; Leukemia; Mice; Pyrazoles; Ribonucleotide Reductases; Tumor Cells, Cultured

1998