hydroxyurea and 2'-deoxycytidine 5'-triphosphate

hydroxyurea has been researched along with 2'-deoxycytidine 5'-triphosphate in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199011 (55.00)18.7374
1990's5 (25.00)18.2507
2000's4 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sasvári-Székely, M; Spasokukotskaja, T; Staub, M; Taljanidisz, J1
Arentsen-Honders, MW; Colly, LP; Kester, MG; Richel, DJ; ter Riet, PM; Willemze, R1
Höglund, L; Pontis, E; Reichard, P1
Chubb, S; Grindey, GB; Heinemann, V; Hertel, LW; Plunkett, W; Sen, A; Xu, YZ1
Akiyama, Y; Kubota, M; Mikawa, H; Takimoto, T; Tanizawa, A1
Schroeder, AL; Srivastava, VK1
Akiyama, Y; Kiriyama, Y; Kitoh, T; Kubota, M; Mikawa, H; Takimoto, T; Tanizawa, A1
Heinemann, V; Plunkett, W1
Eriksson, S; Skog, S; Tribukait, B; Wallström, B1
Bianchi, V; Pontis, E; Reichard, P2
Lagergren, J; Reichard, P1
Kasper, LH; Pfefferkorn, ER1
Tyrsted, G1
Snyder, RD1
Cox, S; Palmer, S1
Chimploy, K; Mathews, CK; Tassotto, ML1
Back, DJ; Hoggard, PG; Johnson, MA; Kewn, S; Sales, SD1
Fagny, C; Robberecht, P; Svoboda, M; Vandevelde, M1
Hori, H; Kawai, Y; Ueda, T; Yoshio, N1

Other Studies

20 other study(ies) available for hydroxyurea and 2'-deoxycytidine 5'-triphosphate

ArticleYear
Compartmentation of dCTP pools disappears after hydroxyurea or araC treatment in lymphocytes.
    FEBS letters, 1992, Feb-03, Volume: 297, Issue:1-2

    Topics: Cytarabine; Deoxycytidine; Deoxycytosine Nucleotides; DNA; G1 Phase; Humans; Hydroxyurea; Lymphocytes; Palatine Tonsil; Phospholipids; S Phase; Thymidine

1992
Increase in Ara-C sensitivity in Ara-C sensitive and -resistant leukemia by stimulation of the salvage and inhibition of the de novo pathway.
    Annals of hematology, 1992, Volume: 65, Issue:1

    Topics: Cell Division; Cytarabine; Deoxycytidine Kinase; Deoxycytosine Nucleotides; DNA; Drug Resistance; Humans; Hydroxyurea; Leukemia, Myeloid; Tumor Cells, Cultured

1992
Deoxyribonucleotide metabolism in hydroxyurea-resistant V79 hamster cells.
    European journal of biochemistry, 1991, Feb-26, Volume: 196, Issue:1

    Topics: Animals; Cell Line; Cricetinae; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; DNA; Drug Resistance; Hydroxyurea; Thymine Nucleotides

1991
Inhibition of ribonucleotide reduction in CCRF-CEM cells by 2',2'-difluorodeoxycytidine.
    Molecular pharmacology, 1990, Volume: 38, Issue:4

    Topics: Cell Line; Cytidine; Deoxycytidine; Deoxycytosine Nucleotides; DNA; Gemcitabine; Humans; Hydroxyurea; Oxidation-Reduction; Ribonucleoside Diphosphate Reductase; Ribonucleotides; Thymine Nucleotides

1990
Differential modulation of 1-beta-D-arabinofuranosylcytosine metabolism by hydroxyurea in human leukemic cell lines.
    Biochemical pharmacology, 1988, May-01, Volume: 37, Issue:9

    Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; B-Lymphocytes; Cell Line; Cytarabine; Deoxyadenine Nucleotides; Deoxyadenosines; Deoxycytidine; Deoxycytosine Nucleotides; Humans; Hydroxyurea; Leukemia; T-Lymphocytes; Thymine Nucleotides; Vidarabine Phosphate

1988
Deoxyribonucleoside triphosphate pools in mutagen sensitive mutants of Neurospora crassa.
    Biochemical and biophysical research communications, 1989, Jul-31, Volume: 162, Issue:2

    Topics: Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; DNA, Fungal; Genes, Fungal; Histidine; Hydroxyurea; Mutation; Neurospora; Neurospora crassa; Thymine Nucleotides

1989
Ara-CTP metabolism following hydroxyurea or methotrexate treatment in human leukemia cell lines.
    Advances in experimental medicine and biology, 1989, Volume: 253B

    Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; Deoxycytidine; Deoxycytosine Nucleotides; Drug Synergism; Humans; Hydroxyurea; Leukemia; Leukemia, Promyelocytic, Acute; Methotrexate; Thymine Nucleotides; Tumor Cells, Cultured

1989
Modulation of deoxynucleotide metabolism by the deoxycytidylate deaminase inhibitor 3,4,5,6-tetrahydrodeoxyuridine.
    Biochemical pharmacology, 1989, Nov-15, Volume: 38, Issue:22

    Topics: Cell Line; Cytarabine; Cytidine Diphosphate; DCMP Deaminase; Deoxycytidine; Deoxycytidine Kinase; Deoxycytosine Nucleotides; Deoxyuridine; Hydroxyurea; Kinetics; Nucleotide Deaminases; Ribonucleotide Reductases; T-Lymphocytes; Tetrahydrouridine; Thymine Nucleotides

1989
Deoxyribonucleoside triphosphate metabolism and the mammalian cell cycle. Effects of hydroxyurea on mutant and wild-type mouse S49 T-lymphoma cells.
    Experimental cell research, 1987, Volume: 168, Issue:1

    Topics: Animals; Cell Cycle; Cell Line; Deoxyadenine Nucleotides; Deoxycytidine Kinase; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; Hydroxyurea; Lymphoma; Mice; Mutation; Purine-Nucleoside Phosphorylase; Ribonucleotide Reductases; T-Lymphocytes; Thymidine Kinase; Thymine Nucleotides

1987
Interrelations between substrate cycles and de novo synthesis of pyrimidine deoxyribonucleoside triphosphates in 3T6 cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:4

    Topics: Animals; Cell Cycle; Cell Line; Deoxycytosine Nucleotides; Deoxyribonucleosides; Deoxyuracil Nucleotides; Dipyridamole; DNA Replication; Fibroblasts; Hydroxyurea; Mice; Phosphorylation; Thymidine Monophosphate; Thymine Nucleotides

1986
Purine deoxyribonucleosides counteract effects of hydroxyurea on deoxyribonucleoside triphosphate pools and DNA synthesis.
    Biochemical pharmacology, 1987, Sep-15, Volume: 36, Issue:18

    Topics: Animals; Cell Line; Cricetinae; Deoxyadenine Nucleotides; Deoxyadenosines; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyguanosine; DNA; Hydroxyurea; Nucleotides; Purine Nucleosides; Thymine Nucleotides

1987
Changes of deoxyribonucleoside triphosphate pools induced by hydroxyurea and their relation to DNA synthesis.
    The Journal of biological chemistry, 1986, Dec-05, Volume: 261, Issue:34

    Topics: Cells, Cultured; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA; Hydroxyurea; Ribonucleotide Reductases; Thymine Nucleotides

1986
Hydroxyurea inhibition of growth and DNA synthesis in Toxoplasma gondii: characterization of a resistant mutant.
    Molecular and biochemical parasitology, 1982, Volume: 6, Issue:3

    Topics: Animals; Cells, Cultured; Deoxycytosine Nucleotides; DNA; Drug Resistance; Fibroblasts; Humans; Hydroxyurea; Mutation; Ribonucleotide Reductases; RNA; Thymine Nucleotides; Toxoplasma

1982
Effect of 5-fluoro-2'-deoxyuridine and hydroxyurea on the phytohemagglutinin-induced increase of thymidine kinase, replicative DNA polymerase, deoxycytidylate deaminase and CDP reductase activities in human lymphocytes.
    Molecular and cellular biochemistry, 1984, Volume: 62, Issue:2

    Topics: Cells, Cultured; DCMP Deaminase; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; DNA Replication; DNA-Directed DNA Polymerase; Enzyme Induction; Floxuridine; Humans; Hydroxyurea; Lymphocyte Activation; Lymphocytes; Phytohemagglutinins; Ribonucleoside Diphosphate Reductase; Thymidine Kinase

1984
Deoxyribonucleoside triphosphate pools in human diploid fibroblasts and their modulation by hydroxyurea and deoxynucleosides.
    Biochemical pharmacology, 1984, May-01, Volume: 33, Issue:9

    Topics: Cells, Cultured; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleosides; Deoxyribonucleotides; Diploidy; Fibroblasts; Humans; Hydroxyurea; Thymine Nucleotides

1984
Increased activation of the combination of 3'-azido-3'-deoxythymidine and 2'-deoxy-3'-thiacytidine in the presence of hydroxyurea.
    Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:2

    Topics: Anti-HIV Agents; Cell Line; Deoxycytosine Nucleotides; Drug Synergism; Hydroxyurea; Lamivudine; Phosphorylation; Thymine Nucleotides; Zidovudine

1997
Ribonucleotide reductase, a possible agent in deoxyribonucleotide pool asymmetries induced by hypoxia.
    The Journal of biological chemistry, 2000, Dec-15, Volume: 275, Issue:50

    Topics: Animals; Cells, Cultured; Cricetinae; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; Hydrogen-Ion Concentration; Hydroxyurea; Hypoxia; Mice; Models, Chemical; Nucleic Acid Synthesis Inhibitors; Oxygen; Recombinant Proteins; Ribonucleotide Reductases; Thymine Nucleotides; Time Factors

2000
The intracellular activation of lamivudine (3TC) and determination of 2'-deoxycytidine-5'-triphosphate (dCTP) pools in the presence and absence of various drugs in HepG2 cells.
    British journal of clinical pharmacology, 2000, Volume: 50, Issue:6

    Topics: Anti-HIV Agents; Cell Survival; Cytidine Triphosphate; Deoxycytosine Nucleotides; Dideoxynucleotides; Drug Interactions; Humans; Hydroxyurea; Lamivudine; Methotrexate; Phosphorylation; Tumor Cells, Cultured; Vidarabine

2000
Ribonucleotide reductase and thymidine phosphorylation: two potential targets of azodicarbonamide.
    Biochemical pharmacology, 2002, Aug-01, Volume: 64, Issue:3

    Topics: Animals; Antineoplastic Agents; Azo Compounds; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Drug Interactions; Hydroxyurea; Immunosuppressive Agents; Methotrexate; Phosphorylation; Ribonucleotide Reductases; Thymidine; Thymine Nucleotides; Tumor Cells, Cultured

2002
Resistance to 9-beta-D-arabinofuranosyl-2-fluoroadenine due to reduced incorporation into DNA from competition by excess deoxyadenosine triphosphate: implications for different sensitivities to nucleoside analogues.
    International journal of hematology, 2005, Volume: 81, Issue:5

    Topics: Animals; Binding, Competitive; Biotransformation; Cell Line, Tumor; Cell Proliferation; Cytarabine; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; DNA; Drug Interactions; Drug Resistance, Neoplasm; Hydroxyurea; Mice; Nucleosides; Vidarabine

2005