Compounds > hydroxypropyl-gamma-cyclodextrin
Page last updated: 2024-09-03

hydroxypropyl-gamma-cyclodextrin and sirolimus

hydroxypropyl-gamma-cyclodextrin has been researched along with sirolimus in 1 studies

Compound Research Comparison

Studies
(hydroxypropyl-gamma-cyclodextrin)		Trials
(hydroxypropyl-gamma-cyclodextrin)		Recent Studies (post-2010)
(hydroxypropyl-gamma-cyclodextrin)		Studies
(sirolimus)		Trials
(sirolimus)		Recent Studies (post-2010) (sirolimus)
8603420,7112,36811,516

Protein Interaction Comparison

ProteinTaxonomyhydroxypropyl-gamma-cyclodextrin (IC50)sirolimus (IC50)
Bile salt export pumpHomo sapiens (human)10
ATP-dependent translocase ABCB1Homo sapiens (human)1.25
Cytochrome P450 3A4Homo sapiens (human)2
Cytochrome P450 2C9 Homo sapiens (human)2
Peptidyl-prolyl cis-trans isomerase FKBP1AMus musculus (house mouse)0.001
Cytochrome P450 2C19Homo sapiens (human)4
Serine/threonine-protein kinase mTORHomo sapiens (human)0.0897
Peptidyl-prolyl cis-trans isomerase FKBP1AHomo sapiens (human)0.0042
Regulatory-associated protein of mTORHomo sapiens (human)0.225
Target of rapamycin complex subunit LST8Homo sapiens (human)0.225
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)1.9
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)1.1

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bertelmann, E; Borchert, HH; Buech, G; Pleyer, U; Siebenbrodt, I1

Other Studies

1 other study(ies) available for hydroxypropyl-gamma-cyclodextrin and sirolimus

ArticleYear
Formulation of sirolimus eye drops and corneal permeation studies.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2007, Volume: 23, Issue:3

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; beta-Cyclodextrins; Chromatography, High Pressure Liquid; Cornea; Drug Stability; Drug Storage; Emulsions; Excipients; gamma-Cyclodextrins; Gels; Hydrophobic and Hydrophilic Interactions; Immunoenzyme Techniques; Immunosuppressive Agents; In Vitro Techniques; Liposomes; Ophthalmic Solutions; Permeability; Poloxamer; Sirolimus; Solubility; Swine

2007