hydroxyproline has been researched along with transforming growth factor beta in 176 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 24 (13.64) | 18.2507 |
| 2000's | 89 (50.57) | 29.6817 |
| 2010's | 52 (29.55) | 24.3611 |
| 2020's | 11 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Cavallini, M; Fiegel, VD; Knighton, DR; Lado, MD; Murray, C; Phillips, GD | 1 |
| Cambrey, AD; Campa, JS; Laurent, GJ; McAnulty, RJ | 1 |
| Giri, SN; Hollinger, MA; Hyde, DM | 1 |
| Brittenham, GM; Horne, W; Kamimura, S; Niemelä, O; Parkkila, S; Tsukamoto, H; Ylä-Herttuala, S | 1 |
| Chambers, RC; Laurent, GJ; McAnulty, RJ | 1 |
| Geraci, JP; Mariano, MS | 1 |
| Chung, KS; Farouk, M; Jirtle, RL; Meyers, WC; Saperstein, LA; Thompson, HJ | 1 |
| Kahn, AJ; Kirk, M; Shi, S | 1 |
| Cutroneo, KR; Ehrlich, HP; Keefer, KA; Meisler, N; Myers-Parrelli, J; Yager, DR | 1 |
| Frizzell, S; Inman, L; Karim, MA; Miller, DD; Shinn, M | 1 |
| Choi, BM; Chung, HT; Jun, CD; Park, SD; Rim, JS | 1 |
| Csaky, KG; Gauldie, J; Graham, FL; Sime, PJ; Xing, Z | 1 |
| Fukagawa, M; Hata, S; Iwasaki, Y; Kuroda, T; Kurokawa, K; Margolin, SB; Nemoto, M; Shimizu, F; Shimizu, T; Shirai, K; Yamauchi, S | 1 |
| Aerssens, J; Dequeker, J; Fabry, G; Lammens, J; Liu, Z | 1 |
| Matsumura, Y; Okita, K; Sakaida, I; Uchida, K | 1 |
| Franco, L; Gomez, BL; Graybill, JR; Najvar, L; Restrepo, A; Restrepo, S | 1 |
| Stearns, ME | 1 |
| Fukagawa, M; Hata, S; Kuroda, T; Kurokawa, K; Margolin, SB; Shimizu, T | 1 |
| Churg, A; Dai, J; Gilks, B; Price, K | 1 |
| Baillie, R; Ferguson, M; Herrick, S; Revis, D; Roberts, A; Shah, M; Thorgeirson, S | 1 |
| Ramires, FJ; Sun, Y; Weber, KT; Zhang, J; Zhang, JQ | 1 |
| Doerner, A; Knopf, D; Kühl, U; Pauschinger, M; Petschauer, S; Poller, W; Schultheiss, HP; Schwimmbeck, PL | 1 |
| Malagelada, JR; Molero, X; Salas, A; Tian, X; Vaquero, E | 1 |
| Barger, MW; Castranova, V; Hubbs, AF; Ma, JK; Ma, JY; Weber, SL | 1 |
| Giri, SN; Gurujeyalakshmi, G; Wang, Y | 2 |
| Dixon, IM; Hao, J; Reid, NL; Roth, JC | 1 |
| Liu, X; Manouilova, LS; Patricia Leuschen, M; Rennard, SI; Spurzem, JR; Umino, T; Wang, H; Zhu, Y | 1 |
| Annoni, G; Arosio, B; Balestrieri, MR; Gagliano, N; Masson, S; Padoani, G; Santambrogio, D; Tagliabue, J; Vergani, C | 1 |
| Allen, D; Halliday, B; Hunt, TK; Roberts, AB; Roche, NS; Scheuenstuhl, H; Spencer, MM; Wicke, C | 1 |
| Galt, T; Gauldie, J; Kolb, M; Margetts, PJ; Schmidt, M; Sime, PJ; Xing, Z | 1 |
| Gauldie, J; Kolb, M; Margetts, PJ; Sime, PJ | 1 |
| Gosselin, LE; Granchelli, JA; Hartel, JV; Hudecki, MS; Pollina, CM | 1 |
| Enjoji, M; Iwamoto, H; Kato, M; Nakamuta, M; Nakashima, Y; Nawata, H; Sugimoto, R; Tada, S | 1 |
| Bent, SJ; Brower-Toland, BD; Fortier, LA; Nixon, AJ; Williams, J; Worster, AA | 1 |
| Bennett, BM; Brien, JF; Chung, WH; Massey, TE; Racz, WJ | 1 |
| Chan, T; Demare, J; Ghahary, A; Iwashina, T; Scott, PG; Tredget, EE; Yang, L | 1 |
| Guo, C; Liu, FT; Xie, WF; Zhang, JP; Zhang, M; Zhou, B; Zhou, JP | 1 |
| Annoni, G; Arosio, B; Dioguardi, N; Gagliano, N; Grizzi, F; Masson, S; Tagliabue, J; Vergani, C | 1 |
| Komai, M; Masuda, T; Nagai, H; Nagao, K; Takahashi, Y; Tanaka, H; Tokuoka, S | 1 |
| Bauer, C; Eschenhagen, T; Godes, M; Hocher, B; Neumayer, HH; Olivier, J; Paul, M; Pinto, YM; Slowinski, T; Weil, J | 1 |
| Idikio, H; Jugdutt, BI; Kumar, D; Menon, V | 1 |
| Furuya, K; Hanada, K; Yamamoto, N | 1 |
| Arai, T; Fujiwara, H; Goya, S; Hayashi, S; Kida, H; Matsuoka, H; Mori, M; Morishita, H; Osaki, T; Tachibana, I | 1 |
| Anselmi, K; Gandhi, CR; Nemoto, E; Subbotin, VM | 1 |
| Breuer, R; Goldstein, RH; Or, R; Segel, MJ; Tzurel, A | 1 |
| Bonniaud, P; Galt, T; Gauldie, J; Kelly, MM; Kolb, M; Margetts, PJ; Sime, PJ | 1 |
| Anscher, MS; Batinic-Haberle, I; Dewhirst, MW; Feng, QF; Fridovich, I; Kang, SK; Rabbani, ZN; Samulski, TV; Spasojevic, I; Vujaskovic, Z | 1 |
| Barbul, A; Efron, DT; Most, D; Shi, HP; Tantry, US | 1 |
| Brien, JF; Card, JW; Massey, TE; Racz, WJ | 1 |
| Abe, S; Bottinger, EP; Fang, Q; Kobayashi, T; Liu, X; Piek, E; Rennard, SI; Roberts, AB; Wen, FQ | 1 |
| Churg, A; Dai, J; Vincent, R; Xie, C | 1 |
| Itoh, M; Joh, T; Kuno, A; Masuda, K; Nakamura, S; Nakazawa, T; Nomura, T; Ogawa, K; Ohara, H; Shirai, T; Sogawa, M; Yamada, T | 1 |
| Fujita, M; Gauldie, J; Hara, N; Mason, RJ; Morikawa, O; Shannon, JM | 1 |
| Brien, JF; Card, JW; Margolin, SB; Massey, TE; Racz, WJ | 1 |
| Becerril, C; Berumen, J; Ordóñez, RM; Pardo, A; Ramírez, R; Ruiz, V; Selman, M; Uhal, B | 1 |
| Chayama, K; Kanno, K; Tazuma, S | 1 |
| Gohil, K; Kenyon, NJ; Last, JA | 1 |
| Ando, T; Itoh, M; Joh, T; Kuno, A; Masuda, K; Nakamura, S; Nakazawa, T; Nomura, T; Ogawa, K; Ohara, H; Sano, H; Sogawa, M; Yamada, T | 1 |
| Etani, Y; Kondou, H; Michigami, T; Miyoshi, Y; Mushiake, S; Ozono, K | 1 |
| Fukami, H; Fukuda, Y; Maruoka, H; Muto, T; Saito, K; Sumida, M; Tanaka, T; Tomimori, Y | 1 |
| Ji, SX; Li, SR; Liu, JY | 1 |
| Aoki, M; Fujigaki, Y; Fukasawa, H; Hishida, A; Hosono, M; Kitagawa, M; Ohashi, N; Suzuki, H; Togawa, A; Uchida, C; Yamamoto, T | 1 |
| Abe, S; Chiba, H; Otsuka, M; Shiratori, M; Takahashi, H | 1 |
| Delespesse, G; Ishizaki, M; Kajiwara, D; Komai, M; Nagai, H; Nagao, K; Takatsu, K; Tanaka, H | 1 |
| Asaumi, H; Nagashio, Y; Nomiyama, Y; Otsuki, M; Sugaya, T; Taguchi, M; Tashiro, M; Watanabe, S | 1 |
| Birch Nielsen, C; Flyvbjerg, A; Forman, A; Krag, S; Nyengaard, J; Wogensen, L; ØSterby, R | 1 |
| He, BM; Jiang, W; Liu, WB; Wang, JY; Wang, YQ; Yang, CQ | 1 |
| Chen, YJ; Huang, HC; Huang, YT; Kuo, YR; Sun, YC; Wang, CJ; Wang, FS; Yang, KD | 1 |
| Kawakita, T; Nomoto, K; Ochi, T | 1 |
| Chen, JQ; Li, J; Xu, SY; Yao, HW | 1 |
| Chen, SJ; DiPietro, LA; Ferreira, AM; Han, G; Lakos, G; Masuda, K; Takagawa, S; Varga, J; Wang, XJ | 1 |
| Ask, K; Bonniaud, P; Gauldie, J; Kolb, M; Margetts, PJ; Martin, G; Robertson, J | 1 |
| Chen, J; Chen, Y; Dong, J; Liu, W | 1 |
| De Clerck, HJ; Delatte, ML; Kuijpers-Jagtman, AM; Nottet, SJ; Von den Hoff, JW | 1 |
| Itoh, M; Kataoka, H; Kuno, A; Nakao, H; Ogawa, K; Ohara, H; Okamoto, T; Sano, H; Shirai, T; Tang, M; Yamada, T | 1 |
| Chen, J; Chen, Y; Dong, J; Jin, Y | 1 |
| Bulbuller, N; Ilhan, YS; Kirkil, C; Ozercan, R; Seckin, D | 1 |
| Boros, DL; Cutroneo, KR; Gerard, HC; Hudson, AP; Singh, KP; White, SL | 1 |
| Bouscarel, B; Doy, M; Ikegami, T; Karube, M; Matsuzaki, Y; Miyazaki, T; Tanaka, N | 1 |
| Hou, LB; Shi, HP; Yang, XX | 1 |
| Bou-Gharios, G; Cobbold, S; Morrison, J; Palmer, DB; Partridge, T | 1 |
| Hu, YY; Liu, CH; Liu, P; Wang, XN; Zhu, DY | 1 |
| Angele, MK; Angele, P; Chaudry, IH; Hernandez-Richter, T; Jauch, KW; Mayr, S; Prix, N; van den Engel, NK; Wichmann, MW; Wittmann, F | 1 |
| Chen, CM; Chou, HC; Hsu, HH; Wang, LF | 1 |
| Chung, DH; Chung, JH; Kim, HY; Kim, JH; Kim, S; Park, WS | 1 |
| Lu, Y; Yao, HW; Zhao, MH; Zhu, JP | 1 |
| Abe, S; Azuma, A; Hirata, Y; Inagaki, H; Kawada, T; Kudoh, S; Li, YJ; Matsuda, K; Omura, S; Shimizu, T; Sunazuka, T; Takahashi, S; Usuki, J | 1 |
| Du, J; Huang, CG; Li, YT; Pei, G; Shen, Y; Tan, F; Zhao, HL | 1 |
| Adawi, D; Agren, MS; Blomquist, P; Gottrup, F; Jeppsson, B; Johnson, LB; Jorgensen, LN; Mattsson, S; Wittgren, L | 1 |
| García-Criado, FJ; García-Sánchez, E; García-Sánchez, JE; Gómez-Alonso, A; Parreño-Manchado, A; Parreño-Manchado, FC; Zambrano-Cuadrado, Y | 1 |
| Gosselin, LE; Williams, JE | 1 |
| Gakis, D; Imvrios, G; Papanikolaou, V; Sikas, N; Takoudas, D | 1 |
| Inoue, K; Kodai, S; Minamiyama, Y; Mizuguchi, S; Okada, S; Suehiro, S; Takemura, S; Tsukioka, T | 1 |
| Cao, Z; Han, G; Peng, M; Xie, CH; Zhang, MS; Zhang, WJ; Zhou, FX; Zhou, YF | 1 |
| Fang, HL; Kuo, SC; Lin, WC; Lin, WL; Wang, BC | 1 |
| McNally, EM; Millay, DP; Molkentin, JD; Parsons, SA; Sargent, MA | 1 |
| Chayama, K; Horiuchi, M; Hyogo, H; Iwai, M; Kanno, K; Nabeshima, Y; Tazuma, S | 1 |
| Brigham, K; Mora, AL; Ritzenthaler, J; Rojas, M; Roman, J; Speck, SH; Stecenko, A; Torres-González, E; Xu, J | 1 |
| Ahn, SC; Baik, SK; Cho, MY; Choi, YH; Kim, CH; Kim, JW; Kim, MY; Kwon, SO; Park, DH; Rhim, DW | 1 |
| Izumo, T; Kondo, M; Nagai, A | 1 |
| Nunoo-Mensah, JW; Ruiz, P; Tzakis, AG; Wasserberg, N | 1 |
| Atsawasuwan, P; Kaku, M; Mochida, Y; Parisuthiman, D; Yamauchi, M | 1 |
| Bilir, A; Gungor, F; Gurdol, F; Suzme, R; Yalcin, O | 1 |
| Argiroffo, CB; Bongiovanni, M; Chizzolini, C; Dayer, JM; Djaafar, S; Donati, Y; Ferrari-Lacraz, S; Fineschi, S; Goffin, L; Naso, F; Pache, JC | 1 |
| Baik, SK; Cho, MY; Choi, SJ; Han, KH; Jang, YO; Kim, HS; Kim, JW; Kim, MY; Suk, KT; Um, SH | 1 |
| Aoyagi, Y; Fukunaga, K; Hashimoto, I; Ikeda, O; Matsuo, R; Murata, S; Nakano, Y; Ohkohchi, N; Watanabe, M; Yasue, H | 1 |
| Fernández-Martínez, E; Galicia-Moreno, M; Moreno, MG; Muriel, P; Pérez-Alvarez, VM; Reyes-Gordillo, K; Rodríguez-Rivera, A; Segovia, J; Shibayama, M; Tsutsumi, V; Vergara, P | 1 |
| Chen, F; Huang, YJ; Liang, L; Wang, ZH; Zhang, JB; Zhao, JH | 1 |
| Boonmars, T; Hiraku, Y; Pinlaor, P; Pinlaor, S; Prakobwong, S; Wongkham, C | 1 |
| Chen, L; Chen, YJ; Li, JQ; Liu, DS; Liu, L; Sun, BB; Wang, T; Wang, X; Wen, FQ; Xu, D; Zhang, SF | 1 |
| Angus, P; Herath, C; Kemp, W; Kompa, A; Krum, H; McLean, C; Phrommintikul, A; Roberts, S; Zhiyuan, J | 1 |
| Boehler, A; Guo, Z; Hofer, M; Rechsteiner, T; Remund, K | 1 |
| Frisbie, DD; Grodzinsky, AJ; Kisiday, JD; Kopesky, PW; Lee, HY; Ortiz, C; Plaas, AH; Vanderploeg, EJ | 1 |
| Enghild, JJ; Englert, JM; Fattman, CL; Kaynar, AM; Leme, AS; Oury, TD; Ramsgaard, L; Shapiro, SD; Tobolewski, J; Tomai, L | 1 |
| Hiraku, Y; Laothong, U; Pinlaor, P; Pinlaor, S; Prakobwong, S; Yongvanit, P | 1 |
| Azuma, A; Hoshino, T; Isohama, Y; Ito, Y; Matoyama, M; Mizushima, T; Namba, T; Tanaka, KI; Yamakawa, N | 1 |
| Du, SS; Liu, ZS; Qiang, M; Tan, YS; Zeng, HY; Zeng, ZC; Zhang, ZY; Zhou, J | 1 |
| Jia, J; Wang, H; Wang, T; You, H; Zhang, Y | 1 |
| Ceci, L; Cheng, SH; Clayton, NP; Dinardo, CJ; Girgenrath, S; Hunter, RB; Keefe, KA; Leonard, JP; McCullough, JA; McVie-Wylie, A; Nelson, CA; Quigley, LA; Weber, WD; Wentworth, BM | 1 |
| Ebeid, F; el-Din, SS; El-Lakkany, N | 1 |
| Knight, V; Lourensz, D; Sievert, W; Tchongue, J; Tipping, P | 1 |
| Favari, L; Galicia-Moreno, M; Muriel, P | 1 |
| Chai, Y; Dong, Z; Li, Y; Tai, W; Wang, D; Yang, Y; Zhang, T; Zhong, H; Zou, H | 1 |
| Guo, Y; Liao, ZX; Wang, H; Wu, XQ; Wu, Y; Zhang, C | 1 |
| Choi, MK; Han, JM; Hwang, SY; Kim, HG; Lee, JS; Park, HJ; Son, CG; Son, SW; Wang, JH | 1 |
| Chuang, VT; Hamasaki, K; Ishima, Y; Kodama, A; Maruyama, T; Mizushima, T; Otagiri, M; Tanaka, K; Tanaka, R; Watanabe, H | 1 |
| Chitra, P; Manikandan, R; Saiprasad, G; Sudhandiran, G | 1 |
| Badr, G | 1 |
| Gao, A; Niu, P; Tian, L; Wang, Y; Yang, G; Zhu, Z | 1 |
| Chu, L; Gao, Y; Li, J; Li, L; Ma, J; Wang, J; Xie, Y; Yuan, J; Zhang, J; Zhang, Y | 1 |
| Dong, W; Lv, B; Wei, F; Yang, L | 1 |
| Fukunaga, K; Murata, S; Ohkohchi, N; Takahashi, K | 1 |
| Canalis, E; Horowitz, JC; Kim, KK; Velikoff, M; Yang, J | 1 |
| In, KH; Kang, KH; Kim, HK; Kim, HS; Kim, JH; Kim, YM; Lee, EJ; Lee, SH; Lee, SY; Park, S; Shim, JJ; Shin, C; Uhm, CS; Yang, KS; Yoo, TJ | 1 |
| Chu, D; Yao, Y; Zhou, C | 1 |
| Chen, F; Gong, H; Ji, A; Tao, H; Wang, K; Ye, F; Zhang, C; Zuo, Z | 1 |
| Choi, MK; Han, JM; Kim, HG; Kim, JM; Lee, DS; Lee, JS; Park, YH; Son, CG | 1 |
| Cui, K; Gu, JH; Han, R; Kou, JQ; Qin, ZH; Wang, G; Zhen, X | 1 |
| Abdullah, M; Ho, CC; Koh, RY; Lim, CL; Seow, HF; Uhal, BD; Vidyadaran, S | 1 |
| Bartalesi, B; Cavarra, E; De Cunto, G; Fineschi, S; Lucattelli, M; Lungarella, G; Lunghi, B | 1 |
| Li, L; Li, Y; Xiong, J; Xu, J; Ye, Q; Zheng, Y | 1 |
| Elsirafy, OM; Hamam, GG; Hasanin, AH; Hussein, RM; Kawy, HS; Wahba, YS | 1 |
| Cai, Y; Kimura, S | 1 |
| Li, D; Li, J; Liu, M; Liu, Y; Liu, Z; Ren, G; Song, L; Xu, P; Yang, Y; Yuan, Q; Zhang, Y | 1 |
| Deng, Y; He, J; Liu, X; Lv, L; Rao, J; Wang, W; Yang, G; Yang, Y; Zhang, G; Zhao, X | 1 |
| Habgood, AN; Jenkins, G; John, AE; Johnson, SR; Laurent, GJ; Porte, J; Tatler, AL; Wahl, SM | 1 |
| Debek, W; Hermanowicz, A; Lebensztejn, DM; Miltyk, W; Moczydlowska, J; Palka, JA | 1 |
| Ayten, R; Binnetoglu, K; Cetinkaya, Z; Duman, K; Girgin, M; Ilhan, N; Ilhan, YS; Kanat, BH; Seker, I; Timurkaan, N | 1 |
| Chung, EJ; Chung, SI; Citrin, DE; McKay-Corkum, G; Mitchell, JB; Sowers, A; Thetford, A | 1 |
| Boccalini, G; Calosi, L; Durante, M; Lanzi, C; Lucarini, L; Mannaioni, G; Masini, E; Moroni, F; Pini, A | 1 |
| Farooqi, H; Ganai, AA; Ganaie, IA; Verma, N | 1 |
| Kuroda, M; Ohno, SI; Sudo, K; Takanashi, M; Ueda, S; Yamada, Y | 1 |
| Carney, KR; Jimenez, SA; Mendoza, FA; Piera-Velazquez, S; Wermuth, PJ | 1 |
| Arauz, J; Favari, L; Galicia-Moreno, M; Hernández-Aquino, E; Muriel, P; Segovia, J; Zarco, N | 1 |
| Dong, J; Han, F; Li, F; Li, H; Liu, X; Luo, M; Qiao, X; Shi, J; Wei, J; Yang, L; Zhang, J | 1 |
| Chen, Z; Guan, L; Huang, L; Pang, Y; Wang, D; Wang, K; Xie, X; Xu, L; Yu, F; Zhang, Y | 1 |
| Huang, A; Li, Z; Lin, Z; Ma, H; Mei, H; Shi, L; Wang, J; Wang, Y; Wu, G; Zhang, T; Zhou, F | 1 |
| Abdelghany, RH; El-Ahwany, E; Helal, NS; Mahmoud, AAA; Saber, S | 1 |
| Anstee, QM; Dhar, A; Goldin, RD; Levene, AP; Sadiq, F; Thursz, MR | 1 |
| Chen, Y; FEng, D; Li, H; Pan, L; Sun, G; Xu, K; Zhang, X | 1 |
| Dai, J; Dai, X; Fang, J; Feng, C; Hao, J; Hao, Y; Li, J; Li, R; Liu, J; Lu, B; Ma, R; Qiao, Z; Ran, Y; Xiong, W; Zhang, J; Zhou, Q | 1 |
| Ahad, A; Ahmad Ansari, M; Ahmad, A; Al-Jenoobi, FI; Al-Mohizea, AM; Ali, N; Khan, A; Raish, M | 1 |
| Abdel-Salam, RM; Ahmed, NA; Mansour, HM; Salama, AAA; Yassen, NN; Zaki, HF | 1 |
| Jiang, H; Ma, J; Qiu, Y; Wang, M; Zhang, M; Zhao, X | 1 |
| El-Demerdash, E; Elfeky, MG; Fawzy, HM; Gad, AM; Mantawy, EM | 1 |
| Jiang, Q; Li, G; Liu, B; Xu, K; Zhang, J | 1 |
| Hang, Y; Li, L; Liu, F; Ma, W; Qian, Y; Shen, Y; Wang, Z; Wei, L; Zhang, S; Zhang, X | 1 |
| Artamonov, A; Dygai, A; Ermakova, N; Madonov, P; Pakhomova, A; Pan, E; Pershina, O; Sandrikina, L; Skurikhin, E; Widera, D; Zhukova, M | 1 |
| Abdel-Naim, AB; Alfarsi, A; Algandaby, MM; Alhakamy, NA; Badr-Eldin, SM; Esmat, A; Fahmy, UA; Koshak, AE; M Abdallah, H; Mujallid, MI; Nasrullah, MZ; Neamatallah, T | 1 |
| Hwang, DW; Ko, MK; Lee, M; Piao, C; Zhuang, C | 1 |
| Bai, L; Chen, YL; Duan, SZ; Li, HX; Liu, Y; Song, ZC; Wang, YL; Zhu, SW | 1 |
| Choe, HM; Li, ZY; Paek, HJ; Quan, BH; Yin, XJ | 1 |
| Abdelmonsif, DA; Ali, RG; Badae, NM; Nassar, SZ | 1 |
| Abdevand, ZZ; Khorsandi, L; Malayeri, A; Salimi, A; Siahpoosh, A | 1 |
| Abdelmeged, AA; Asker, ME; Eissa, RG; Shaheen, MA | 1 |
2 trial(s) available for hydroxyproline and transforming growth factor beta
| Article | Year |
|---|---|
Dilated cardiomyopathy is associated with significant changes in collagen type I/III ratio.
Topics: Biopsy; Cardiomyopathy, Dilated; Collagen; Female; Gene Expression Regulation; Hemodynamics; Humans; Hydroxyproline; Male; Middle Aged; Myocarditis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transforming Growth Factor beta | 1999 |
Sodium hydrosulfide and bone marrow derived mesenchymal stem cells combined therapy for bleomycin induced pulmonary fibrosis in rats: Implication of micro RNA-21 and Lnc GAS5.
Topics: Animals; Bleomycin; Bone Marrow; Caspases; Hydrogen Sulfide; Hydroxyproline; Male; Mesenchymal Stem Cells; MicroRNAs; Pulmonary Fibrosis; Rats; Rats, Wistar; RNA, Long Noncoding; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2022 |
174 other study(ies) available for hydroxyproline and transforming growth factor beta
| Article | Year |
|---|---|
Induction of neointima formation by platelet derived angiogenesis fraction in a small diameter, wide pore, PTFE graft.
Topics: Animals; Blood Platelets; Blood Vessel Prosthesis; Cells, Cultured; Endothelium, Vascular; Hydroxyproline; Male; Neovascularization, Pathologic; Polytetrafluoroethylene; Rabbits; Rats; Rats, Inbred Lew; Transforming Growth Factor beta; Vascular Patency | 1992 |
The effect of transforming growth factor beta on rates of procollagen synthesis and degradation in vitro.
Topics: Animals; Cells, Cultured; Chromatography, High Pressure Liquid; DNA; Fibroblasts; Hydroxyproline; Procollagen; Protein Processing, Post-Translational; Rats; RNA, Messenger; Transforming Growth Factor beta | 1991 |
Effect of antibody to transforming growth factor beta on bleomycin induced accumulation of lung collagen in mice.
Topics: Animals; Antibodies; Bleomycin; Collagen; Hydroxyproline; Immunoglobulin G; Lung; Male; Mice; Pulmonary Fibrosis; Transforming Growth Factor beta | 1993 |
Experimental liver cirrhosis induced by alcohol and iron.
Topics: Animals; Collagen; Hydroxyproline; Iron; Lipid Peroxidation; Liver; Liver Cirrhosis, Alcoholic; Liver Cirrhosis, Experimental; Male; Rats; Rats, Wistar; RNA, Messenger; Transforming Growth Factor beta | 1995 |
Regulation of fibroblast procollagen production. Transforming growth factor-beta 1 induces prostaglandin E2 but not procollagen synthesis via a pertussis toxin-sensitive G-protein.
Topics: Animals; Dinoprostone; Fibroblasts; Gene Expression Regulation; GTP-Binding Proteins; Humans; Hydroxyproline; Lung; Pertussis Toxin; Procollagen; Rats; Signal Transduction; Transforming Growth Factor beta; Virulence Factors, Bordetella | 1995 |
Radiation hepatology of the rat: the effects of the proliferation stimulus induced by subtotal hepatectomy.
Topics: Animals; Aspartate Aminotransferases; Cell Division; Dose-Response Relationship, Radiation; Hepatectomy; Hydroxyproline; Liver; Liver Regeneration; Male; Necrosis; Rats; Transforming Growth Factor beta | 1994 |
Transforming growth factor-beta 1 and mannose 6-phosphate/insulin-like growth factor-II receptor expression during intrahepatic bile duct hyperplasia and biliary fibrosis in the rat.
Topics: Animals; Bile Duct Diseases; Bile Ducts, Intrahepatic; Common Bile Duct; DNA; Fibrosis; Hydroxyproline; Hyperplasia; Immunohistochemistry; Ligation; Liver; Male; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 2; Transforming Growth Factor beta | 1994 |
The role of type I collagen in the regulation of the osteoblast phenotype.
Topics: Alkaline Phosphatase; Bone Morphogenetic Proteins; Cell Differentiation; Cell Line; Collagen; Cytokines; Extracellular Matrix; Hydroxyproline; Osteoblasts; Osteopontin; Phenotype; RNA, Messenger; Sialoglycoproteins; Transforming Growth Factor beta; Tretinoin | 1996 |
Dexamethasone abrogates the fibrogenic effect of transforming growth factor-beta in rat granuloma and granulation tissue fibroblasts.
Topics: Animals; Collagen; Dexamethasone; Fibroblasts; Granulation Tissue; Granuloma; Hydroxyproline; Male; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Transfection; Transforming Growth Factor beta | 1997 |
In vivo role of glucocorticoids in barotrauma vascular repair and fibrosis.
Topics: Angioplasty; Animals; Barotrauma; Blood Vessels; Cross-Sectional Studies; Dexamethasone; DNA; Fibrosis; Glucocorticoids; Hydroxyproline; Linear Models; Male; Procollagen; Proteins; Rabbits; RNA; RNA, Messenger; Transforming Growth Factor beta | 1997 |
Antisense transforming growth factor-beta 1 in wound healing.
Topics: Animals; Blotting, Northern; Cicatrix; Drug Evaluation, Preclinical; Enzyme Induction; Fibrosis; Gene Expression Regulation; Hydroxyproline; Mice; Mice, Inbred BALB C; Nitric Oxide Synthase; Oligonucleotides, Antisense; RNA, Messenger; Single-Blind Method; Thionucleotides; Transforming Growth Factor beta; Wound Healing; Wounds, Stab | 1997 |
Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung.
Topics: Actins; Adenoviridae; Animals; Collagen; Elastin; Fibronectins; Gene Transfer Techniques; Genetic Vectors; Hydroxyproline; Lung; Male; Peptide Fragments; Protein Precursors; Proteins; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 1997 |
Pirfenidone prevents collagen accumulation in the remnant kidney in rats with partial nephrectomy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Northern; Body Weight; Collagen; Creatinine; Fibrosis; Hydroxyproline; Kidney; Male; Nephrectomy; Pyridones; Rats; Rats, Wistar; RNA, Messenger; Transforming Growth Factor beta | 1997 |
Distraction bone healing versus osteotomy healing: a comparative biochemical analysis.
Topics: Alkaline Phosphatase; Animals; Bone Lengthening; Bony Callus; Collagen; Dogs; Fracture Healing; Growth Substances; Hindlimb; Hydroxyproline; Insulin-Like Growth Factor I; Osteocalcin; Osteotomy; Phosphoproteins; Transforming Growth Factor beta | 1998 |
Interferon gamma treatment prevents procollagen gene expression without affecting transforming growth factor-beta1 expression in pig serum-induced rat liver fibrosis in vivo.
Topics: Animals; Antiviral Agents; Biomarkers; Blotting, Northern; Dose-Response Relationship, Drug; Gene Expression; Hydroxyproline; Interferon-gamma; Liver; Liver Cirrhosis, Experimental; Male; Microscopy, Electron; Procollagen; Rats; Rats, Wistar; RNA, Messenger; Swine; Transforming Growth Factor beta | 1998 |
Experimental pulmonary fibrosis induced by Paracoccidioides brasiliensis conidia: measurement of local host responses.
Topics: Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Female; Granuloma; Hydroxyproline; Lung; Lung Diseases, Fungal; Male; Mice; Mice, Inbred BALB C; Paracoccidioides; Paracoccidioidomycosis; Pulmonary Fibrosis; Specific Pathogen-Free Organisms; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 1998 |
Alendronate blocks TGF-beta1 stimulated collagen 1 degradation by human prostate PC-3 ML cells.
Topics: Alendronate; Antineoplastic Agents; Bone Neoplasms; Collagen; Gelatinases; Humans; Hydroxyproline; Male; Matrix Metalloproteinase 2; Metalloendopeptidases; Prostatic Neoplasms; Transforming Growth Factor beta; Tritium; Tumor Cells, Cultured | 1998 |
Pirfenidone improves renal function and fibrosis in the post-obstructed kidney.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Collagen; Disease Models, Animal; Fibrosis; Gelatinases; Hydroxyproline; Inulin; Kidney Cortex; Kidney Function Tests; Ligation; Male; Matrix Metalloproteinase 2; Metalloendopeptidases; Pyridones; Rats; Rats, Sprague-Dawley; RNA, Messenger; RNA, Ribosomal, 18S; RNA, Ribosomal, 28S; Transforming Growth Factor beta; Ureter; Ureteral Obstruction | 1998 |
Mineral dusts directly induce epithelial and interstitial fibrogenic mediators and matrix components in the airway wall.
Topics: Airway Obstruction; Animals; Asbestos, Amosite; Culture Techniques; Dust; Epithelium; Extracellular Matrix Proteins; Ferric Compounds; Fibronectins; Gene Expression Regulation; Hydroxyproline; Inflammation Mediators; Irritants; Lung; Male; Mineral Fibers; Minerals; Platelet-Derived Growth Factor; Procollagen; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-sis; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Titanium; Transforming Growth Factor beta; Tropoelastin; Tumor Necrosis Factor-alpha; Up-Regulation | 1998 |
Role of elevated plasma transforming growth factor-beta1 levels in wound healing.
Topics: Animals; Cicatrix; Hydroxyproline; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Polyvinyls; Protein Isoforms; Receptors, Transforming Growth Factor beta; Skin; Surgical Sponges; Swine; Time Factors; Transforming Growth Factor beta; Wound Healing | 1999 |
Appearance and regression of rat pouch tissue.
Topics: Animals; Cheek; Collagen; Collagenases; Fibrosis; Hydroxyproline; Male; Matrix Metalloproteinase 1; Mouth Mucosa; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transforming Growth Factor beta | 1999 |
Myofibroblast proliferation, fibrosis, and defective pancreatic repair induced by cyclosporin in rats.
Topics: Actins; Acute Disease; Animals; Cell Division; Ceruletide; Collagenases; Cyclosporine; Fibrosis; Gastrointestinal Agents; Hydroxyproline; Immunosuppressive Agents; Male; Pancreas; Pancreatitis; Rats; Rats, Wistar; Regeneration; Transforming Growth Factor beta | 1999 |
Use of tetrandrine to differentiate between mechanisms involved in silica-versus bleomycin-induced fibrosis.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antineoplastic; Benzylisoquinolines; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Count; Hydroxyproline; Interleukin-1; L-Lactate Dehydrogenase; Luminescent Measurements; Lung; Macrophages, Alveolar; Male; Organ Size; Phospholipids; Proteins; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Silicon Dioxide; Time Factors; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 1999 |
Taurine and niacin block lung injury and fibrosis by down-regulating bleomycin-induced activation of transcription nuclear factor-kappaB in mice.
Topics: Animals; Anti-Bacterial Agents; Bleomycin; Blotting, Western; Bronchoalveolar Lavage Fluid; Down-Regulation; Hydroxyproline; Interleukin-1; Interleukin-6; Lung Diseases; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Niacin; Pulmonary Fibrosis; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Taurine; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2000 |
Effect of chronic AT(1) receptor blockade on cardiac Smad overexpression in hereditary cardiomyopathic hamsters.
Topics: Analysis of Variance; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blotting, Northern; Blotting, Western; Cardiomyopathy, Dilated; Collagen; Cricetinae; DNA-Binding Proteins; Female; Fluorescent Antibody Technique; Hydroxyproline; Losartan; Male; Matrix Metalloproteinases; Mesocricetus; Myocardium; RNA, Messenger; Signal Transduction; Smad2 Protein; Trans-Activators; Transforming Growth Factor beta | 2000 |
Modification of type I collagenous gels by alveolar epithelial cells.
Topics: Animals; Antibodies; Bronchi; Cell Count; Cell Culture Techniques; Cell Size; Collagen; Cytoskeletal Proteins; Dinoprostone; Epithelial Cells; Fetus; Fluorescent Antibody Technique; Gels; Humans; Hydroxyproline; Integrin beta1; Paxillin; Phenotype; Phosphoproteins; Pulmonary Alveoli; Rats; Transforming Growth Factor beta; Tubulin; Tumor Cells, Cultured | 2000 |
Age-dependent expression of fibrosis-related genes and collagen deposition in rat kidney cortex.
Topics: Age Factors; Animals; Collagen; Fibrosis; Gene Expression; Hydroxyproline; Kidney Cortex; Male; Matrix Metalloproteinase 1; Matrix Metalloproteinase 2; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transforming Growth Factor beta | 2000 |
Effects of steroids and retinoids on wound healing.
Topics: Alitretinoin; Animals; Anti-Inflammatory Agents; Collagen; Hydroxyproline; Insulin-Like Growth Factor I; Male; Methylprednisolone; Methylprednisolone Acetate; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta; Tretinoin; Wound Healing | 2000 |
Transient transgene expression of decorin in the lung reduces the fibrotic response to bleomycin.
Topics: Adenoviridae; Animals; Antibiotics, Antineoplastic; Bleomycin; Decorin; Extracellular Matrix Proteins; Female; Hydroxyproline; Lung; Mice; Mice, Inbred C57BL; Proteoglycans; Pulmonary Fibrosis; Transforming Growth Factor beta; Transgenes; Tumor Cells, Cultured | 2001 |
Proteoglycans decorin and biglycan differentially modulate TGF-beta-mediated fibrotic responses in the lung.
Topics: Adenoviridae; Animals; Biglycan; Bronchoalveolar Lavage Fluid; Cell Line; Decorin; Dose-Response Relationship, Drug; Extracellular Matrix Proteins; Female; Fibroblasts; Gene Transfer Techniques; Genetic Vectors; Humans; Hydroxyproline; Immunohistochemistry; Lung; Mice; Mice, Inbred C57BL; Proteoglycans; Pulmonary Fibrosis; Tissue Distribution; Transforming Growth Factor beta; Treatment Outcome | 2001 |
Impact of prednisone on TGF-beta1 and collagen in diaphragm muscle from mdx mice.
Topics: Animals; Collagen; Cross-Linking Reagents; Diaphragm; Glucocorticoids; Hydroxyproline; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Prednisone; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2001 |
Pirfenidone inhibits dimethylnitrosamine-induced hepatic fibrosis in rats.
Topics: Animals; Blotting, Northern; Body Weight; Collagen; Dimethylnitrosamine; Hydroxyproline; Liver Cirrhosis; Male; Pyridones; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transforming Growth Factor beta | 2001 |
Chondrocytic differentiation of mesenchymal stem cells sequentially exposed to transforming growth factor-beta1 in monolayer and insulin-like growth factor-I in a three-dimensional matrix.
Topics: Animals; Cell Culture Techniques; Cell Differentiation; Chondrocytes; Collagen; Fibrin; Gene Expression; Glycosaminoglycans; Horses; Hydroxyproline; Immunohistochemistry; In Situ Hybridization; Insulin-Like Growth Factor I; Mesoderm; RNA, Messenger; Stem Cells; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2001 |
Induction of c-jun and TGF-beta 1 in Fischer 344 rats during amiodarone-induced pulmonary fibrosis.
Topics: Amiodarone; Animals; Gene Expression Regulation; Humans; Hydroxyproline; Immunohistochemistry; Lung; Male; Proto-Oncogene Proteins c-jun; Pulmonary Fibrosis; Rats; Rats, Inbred F344; RNA, Messenger; Severity of Illness Index; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2001 |
Healing of burn wounds in transgenic mice overexpressing transforming growth factor-beta 1 in the epidermis.
Topics: Animals; Burns; Cell Division; Collagen Type I; Epidermis; Gene Expression Regulation; Humans; Hydroxyproline; Immunohistochemistry; Keratin-14; Keratinocytes; Keratins; Lasers; Mice; Mice, Transgenic; Promoter Regions, Genetic; Recombinant Fusion Proteins; RNA, Messenger; Skin; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transgenes; Wound Healing | 2001 |
Antifibrotic effects of matrine on in vitro and in vivo models of liver fibrosis in rats.
Topics: 3T3 Cells; Alkaloids; Animals; Carbon Tetrachloride Poisoning; Cell Division; Cell Line; Collagen; Hepatocytes; Hyaluronic Acid; Hydroxyproline; Liver Cirrhosis; Male; Matrines; Mice; Platelet-Derived Growth Factor; Quinolizines; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2001 |
Reduced collagenolytic activity of matrix metalloproteinases and development of liver fibrosis in the aging rat.
Topics: Aging; Animals; Collagen Type I; Collagen Type III; Gene Expression; Hydroxyproline; Liver; Liver Cirrhosis; Male; Matrix Metalloproteinase 1; Matrix Metalloproteinase 2; Organ Size; Rats; Rats, Sprague-Dawley; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2002 |
Suppression of bleomycin-induced increased production of nitric oxide and NF-kB activation by treatment with taurine and niacin.
Topics: Animals; Antioxidants; Bleomycin; DNA-Binding Proteins; Hydroxyproline; I-kappa B Proteins; Interleukin-1; Lung; Male; Mice; Mice, Inbred C57BL; NF-kappa B; NF-KappaB Inhibitor alpha; Niacin; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidants; Taurine; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2000 |
The effect of allergen-induced airway inflammation on airway remodeling in a murine model of allergic asthma.
Topics: Acetylcholine; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Collagen; Cytokines; Epithelial Cells; Female; Hydroxyproline; Hypersensitivity; Immunoglobulin E; Immunoglobulin G; Immunoglobulins; Lung; Mice; Mice, Inbred BALB C; Respiratory System; Transforming Growth Factor beta | 2001 |
Inhibition of left ventricular fibrosis by tranilast in rats with renovascular hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cell Division; Fibrosis; Heart Ventricles; Hydroxyproline; Hypertension, Renovascular; In Vitro Techniques; Isoquinolines; Male; Myocardium; ortho-Aminobenzoates; Quinapril; Rats; Rats, Inbred WKY; Tetrahydroisoquinolines; Transforming Growth Factor beta; Ventricular Remodeling | 2002 |
Vascular remodeling during healing after myocardial infarction in the dog model: effects of reperfusion, amlodipine and enalapril.
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Animals; Biomarkers; Calcium Channel Blockers; Collagen; Coronary Vessels; Disease Models, Animal; Dogs; Echocardiography; Enalapril; Hydroxyproline; In Vitro Techniques; Myocardial Infarction; Myocardial Reperfusion; Transforming Growth Factor beta; Ventricular Remodeling | 2002 |
Progressive development of the osteoblast phenotype during differentiation of osteoprogenitor cells derived from fetal rat calvaria: model for in vitro bone formation.
Topics: Animals; Bone Morphogenetic Proteins; Cell Differentiation; Cell Separation; Cells, Cultured; Collagen; Dexamethasone; Female; Fetus; Gene Expression Regulation, Developmental; Hydroxyproline; Osteoblasts; Osteogenesis; Phenotype; Pregnancy; Rats; Rats, Sprague-Dawley; Skull; Stem Cells; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2002 |
A p38 MAPK inhibitor, FR-167653, ameliorates murine bleomycin-induced pulmonary fibrosis.
Topics: Activating Transcription Factor 2; Animals; Antibiotics, Antineoplastic; Bleomycin; Bronchoalveolar Lavage Fluid; Connective Tissue Growth Factor; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Gene Expression; Growth Inhibitors; Growth Substances; Hydroxyproline; Immediate-Early Proteins; In Situ Nick-End Labeling; Injections, Intravenous; Intercellular Signaling Peptides and Proteins; Lung; Male; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pulmonary Fibrosis; Pyrazoles; Pyridines; RNA, Messenger; Transcription Factors; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Weight Gain | 2002 |
Accelerated reversal of carbon tetrachloride-induced cirrhosis in rats by the endothelin receptor antagonist TAK-044.
Topics: Animals; Arteries; Blood Pressure; Carbon Tetrachloride; Collagen; Collagenases; Endothelin Receptor Antagonists; Endothelin-1; Hydroxyproline; Liver; Liver Cirrhosis; Male; Peptides, Cyclic; Portal Vein; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptors, Endothelin; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2002 |
Halofuginone does not reduce fibrosis in bleomycin-induced lung injury.
Topics: Angiogenesis Inhibitors; Animals; Antimetabolites, Antineoplastic; Bleomycin; Blotting, Northern; Bronchoalveolar Lavage Fluid; Cell Count; Collagen; Fibroblasts; Gene Expression Regulation; Hydroxyproline; Intubation, Intratracheal; Lung; Male; Piperidines; Pulmonary Fibrosis; Quinazolines; Quinazolinones; Rats; Rats, Sprague-Dawley; RNA; Transforming Growth Factor beta | 2002 |
Differences in the fibrogenic response after transfer of active transforming growth factor-beta1 gene to lungs of "fibrosis-prone" and "fibrosis-resistant" mouse strains.
Topics: Adenoviridae; Animals; Bronchoalveolar Lavage Fluid; Cell Line; Collagen; Female; Fibroblasts; Gene Transfer Techniques; Genetic Vectors; Humans; Hydroxyproline; Inflammation; Lung; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Protease Inhibitors; Pulmonary Fibrosis; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2002 |
A small molecular weight catalytic metalloporphyrin antioxidant with superoxide dismutase (SOD) mimetic properties protects lungs from radiation-induced injury.
Topics: Animals; Antioxidants; Collagen; Female; Fibrosis; Free Radicals; Hydroxyproline; Immunohistochemistry; Lung; Lung Injury; Metalloporphyrins; Radiation Injuries; Rats; Rats, Inbred F344; Respiration; Superoxide Dismutase; Thoracic Neoplasms; Time Factors; Transforming Growth Factor beta | 2002 |
Characterization of incisional wound healing in inducible nitric oxide synthase knockout mice.
Topics: Animals; Cell Survival; Dermatologic Surgical Procedures; Endothelial Growth Factors; Hydroxyproline; In Situ Hybridization; Intercellular Signaling Peptides and Proteins; Interleukin-4; Lymphokines; Mice; Mice, Knockout; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Skin; Surgical Wound Dehiscence; Tensile Strength; Transforming Growth Factor beta; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Wound Healing | 2002 |
Attenuation of amiodarone-induced pulmonary fibrosis by vitamin E is associated with suppression of transforming growth factor-beta1 gene expression but not prevention of mitochondrial dysfunction.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Antioxidants; Cricetinae; Diet; DNA Probes; Gene Expression; Hydroxyproline; In Situ Hybridization; Lung; Male; Membrane Potentials; Mesocricetus; Mitochondria; Oxygen Consumption; Polarography; Pulmonary Fibrosis; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1; Vitamin E | 2003 |
Smad3 mediates the TGF-beta-induced contraction of type I collagen gels by mouse embryo fibroblasts.
Topics: Animals; Collagen Type I; DNA; DNA-Binding Proteins; Embryo, Mammalian; Fibroblasts; Hydroxyproline; Mice; Smad3 Protein; Trans-Activators; Transforming Growth Factor beta | 2003 |
Air pollution particles produce airway wall remodeling in rat tracheal explants.
Topics: Air Pollution; alpha-Fetoproteins; Animals; Cells, Cultured; Chelating Agents; Collagen; Deferoxamine; DNA, Complementary; Enzyme Inhibitors; Fibrosis; Flavonoids; Gene Expression Regulation; Hydroxyproline; Imidazoles; Iron; Mitogen-Activated Protein Kinases; NF-kappa B; Organ Culture Techniques; Oxidants; p38 Mitogen-Activated Protein Kinases; Peptides; Procollagen; Promoter Regions, Genetic; Pyridines; Rats; Thiourea; Time Factors; Trachea; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2003 |
Angiotensin-converting enzyme inhibitor attenuates pancreatic inflammation and fibrosis in male Wistar Bonn/Kobori rats.
Topics: Actins; Angiotensin-Converting Enzyme Inhibitors; Animals; Body Weight; Chronic Disease; Fibrosis; Gene Expression; Hydroxyproline; Immunohistochemistry; Lisinopril; Male; Organ Size; Pancreas; Pancreatitis; Peptidyl-Dipeptidase A; Peroxidase; Rats; Rats, Wistar; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2003 |
Overexpression of tumor necrosis factor-alpha diminishes pulmonary fibrosis induced by bleomycin or transforming growth factor-beta.
Topics: Adenoviridae; Animals; Antibiotics, Antineoplastic; Bleomycin; Cytokines; Dinoprostone; Fibrosis; Genetic Vectors; Humans; Hydroxyproline; Lung; Mice; Mice, Transgenic; Receptors, Tumor Necrosis Factor; Recombinant Proteins; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2003 |
Differential effects of pirfenidone on acute pulmonary injury and ensuing fibrosis in the hamster model of amiodarone-induced pulmonary toxicity.
Topics: Acute Disease; Amiodarone; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Bleomycin; Cricetinae; Disease Models, Animal; Hydroxyproline; Male; Membrane Potentials; Mitochondria; Oxygen Consumption; Pulmonary Fibrosis; Pyridones; RNA, Messenger; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2003 |
Unbalanced collagenases/TIMP-1 expression and epithelial apoptosis in experimental lung fibrosis.
Topics: Animals; Apoptosis; Base Sequence; Biomarkers; Blotting, Northern; Collagenases; Disease Models, Animal; DNA Primers; Female; Gene Expression Regulation; Hydroxyproline; Male; Polymerase Chain Reaction; Pulmonary Fibrosis; Rats; Rats, Wistar; Respiratory Mucosa; Time Factors; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta | 2003 |
AT1A-deficient mice show less severe progression of liver fibrosis induced by CCl(4).
Topics: Animals; Base Sequence; Carbon Tetrachloride; DNA Primers; Enzyme-Linked Immunosorbent Assay; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Mice; Mice, Knockout; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2003 |
Susceptibility to ovalbumin-induced airway inflammation and fibrosis in inducible nitric oxide synthetase-deficient mice: mechanisms and consequences.
Topics: Aerosols; Animals; Cell Count; Collagen; Coloring Agents; Fibrosis; Gene Expression Regulation, Enzymologic; Hydroxyproline; Inflammation; Injections, Spinal; Lung; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Ovalbumin; Respiratory System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Fixation; Transforming Growth Factor beta | 2003 |
Candesartan, an angiotensin II receptor antagonist, suppresses pancreatic inflammation and fibrosis in rats.
Topics: Actins; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Body Weight; Fibrosis; Hydroxyproline; Immunohistochemistry; Inflammation; Male; Muscle, Smooth; Organ Size; Pancreatitis; Peroxidase; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta | 2003 |
A blocking peptide for transforming growth factor-beta1 activation prevents hepatic fibrosis in vivo.
Topics: Animals; Atrophy; Dimethylnitrosamine; Disease Progression; DNA-Binding Proteins; Hydroxyproline; Liver; Liver Cirrhosis; Male; Necrosis; Peptides; Phosphorylation; Rats; Rats, Sprague-Dawley; Smad2 Protein; Trans-Activators; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2003 |
Involvement of mast cell chymase in bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Antibiotics, Antineoplastic; Biotransformation; Bleomycin; Chymases; Dose-Response Relationship, Drug; Fibroblasts; Humans; Hydroxyproline; Lung; Male; Mast Cells; Mice; Mice, Inbred ICR; Mitogens; Pulmonary Fibrosis; Recombinant Proteins; Serine Endopeptidases; Transforming Growth Factor beta | 2003 |
[Expression of connective tissue growth factor gene in the hypertrophic scar and keloid tissue].
Topics: Adolescent; Adult; Cicatrix, Hypertrophic; Connective Tissue Growth Factor; Female; Gene Expression; Humans; Hydroxyproline; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Keloid; Male; Middle Aged; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin; Transforming Growth Factor beta | 2003 |
Treatment with anti-TGF-beta antibody ameliorates chronic progressive nephritis by inhibiting Smad/TGF-beta signaling.
Topics: Animals; Body Weight; Collagen; Collagen Type I; DNA-Binding Proteins; Down-Regulation; Female; Glomerulonephritis; Hydroxyproline; Immunoglobulin G; Immunotherapy; Kidney Cortex; Kidney Failure, Chronic; Male; Plasminogen Activator Inhibitor 1; Proteinuria; Rats; Rats, Wistar; RNA, Messenger; Sheep; Signal Transduction; Smad2 Protein; Smad3 Protein; Trans-Activators; Transforming Growth Factor beta | 2004 |
Reduction of bleomycin induced lung fibrosis by candesartan cilexetil, an angiotensin II type 1 receptor antagonist.
Topics: Albumins; Angiotensin II Type 1 Receptor Blockers; Animals; Antibiotics, Antineoplastic; Benzimidazoles; Biphenyl Compounds; Bleomycin; Blotting, Western; Bronchoalveolar Lavage Fluid; Hydroxyproline; Immunohistochemistry; Male; Proteins; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Tetrazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
Role of interleukin-5 and eosinophils in allergen-induced airway remodeling in mice.
Topics: Actins; Allergens; Animals; Antibodies; Asthma; Bronchi; Chemotaxis, Leukocyte; Collagen; Disease Models, Animal; Disease Progression; Eosinophils; Female; Fibroblasts; Hydroxyproline; Interleukin-5; Mice; Mice, Knockout; Ovalbumin; Pulmonary Fibrosis; Receptors, Interleukin; Receptors, Interleukin-5; Transforming Growth Factor beta; Transforming Growth Factor beta1; Up-Regulation | 2004 |
Angiotensin II type 1 receptor interaction is an important regulator for the development of pancreatic fibrosis in mice.
Topics: Animals; Ceruletide; Fibrosis; Hydroxyproline; Mice; Mice, Inbred C57BL; Mice, Knockout; Pancreas; Pancreatic Diseases; Protein Isoforms; Receptor, Angiotensin, Type 1; Recurrence; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
Transforming growth factor beta1-induced glomerulopathy is prevented by 17beta-estradiol supplementation.
Topics: Animals; Basement Membrane; Disease Models, Animal; Estradiol; Extracellular Matrix; Female; Gene Expression; Glomerulonephritis; Hydroxyproline; Kidney; Kidney Failure, Chronic; Kidney Glomerulus; Male; Mice; Mice, Inbred BALB C; Mice, Transgenic; Promoter Regions, Genetic; Renin; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transgenes | 2004 |
Blockage of transforming growth factor beta receptors prevents progression of pig serum-induced rat liver fibrosis.
Topics: Activin Receptors, Type I; Animals; Blood Proteins; Blotting, Northern; Blotting, Western; Collagen Type I; Collagen Type II; DNA, Antisense; Enzyme-Linked Immunosorbent Assay; Gene Expression; Genetic Therapy; Hydroxyproline; Liver; Liver Cirrhosis; Male; Plasmids; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Receptor, Transforming Growth Factor-beta Type I; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; RNA, Messenger; Swine; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
Extracorporeal shock waves promote healing of collagenase-induced Achilles tendinitis and increase TGF-beta1 and IGF-I expression.
Topics: Achilles Tendon; Animals; Biomechanical Phenomena; Collagenases; Disease Models, Animal; DNA; Dose-Response Relationship, Radiation; Glycosaminoglycans; High-Energy Shock Waves; Hydroxyproline; Insulin-Like Growth Factor I; Rats; Rats, Sprague-Dawley; Tendinopathy; Tendon Injuries; Transforming Growth Factor beta; Transforming Growth Factor beta1; Wound Healing | 2004 |
Effects of Hochu-ekki-to and Ninjin-youei-to, traditional Japanese medicines, on porcine serum-induced liver fibrosis in rats.
Topics: Animals; Collagen Type IV; Drugs, Chinese Herbal; Female; Hydroxyproline; Interleukin-13; Japan; Liver Cirrhosis; Phytotherapy; Procollagen-Proline Dioxygenase; Rats; Rats, Wistar; Sus scrofa; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
Inhibitory effect of leflunomide on hepatic fibrosis induced by CCl4 in rats.
Topics: Adjuvants, Immunologic; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Collagen Type III; Hydroxyproline; Isoxazoles; Leflunomide; Liver; Liver Cirrhosis, Experimental; Male; NF-kappa B; Nitric Oxide; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
Targeted disruption of TGF-beta/Smad3 signaling modulates skin fibrosis in a mouse model of scleroderma.
Topics: Actins; Animals; Bleomycin; Blotting, Western; Cells, Cultured; Collagen; Connective Tissue Growth Factor; Disease Models, Animal; Fibroblasts; Fibronectins; Fibrosis; Flow Cytometry; Gene Expression Regulation; Gene Targeting; Hydroxyproline; Immediate-Early Proteins; Immunohistochemistry; In Situ Hybridization; Intercellular Signaling Peptides and Proteins; Mice; Mice, Knockout; Scleroderma, Systemic; Signal Transduction; Skin; Trans-Activators; Transforming Growth Factor beta | 2004 |
Connective tissue growth factor is crucial to inducing a profibrotic environment in "fibrosis-resistant" BALB/c mouse lungs.
Topics: Adenoviridae; Animals; Bleomycin; Bronchoalveolar Lavage; Connective Tissue Growth Factor; DNA Primers; Female; Fibrosis; Gene Transfer Techniques; Genetic Predisposition to Disease; Hydroxyproline; Immediate-Early Proteins; Inflammation; Intercellular Signaling Peptides and Proteins; Lung; Metalloproteases; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Polymerase Chain Reaction; Risk; RNA, Messenger; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Up-Regulation | 2004 |
Antifibrotic effect of interferon gamma in silicosis model of rat.
Topics: Animals; Disease Models, Animal; Female; Hydroxyproline; Immunohistochemistry; Interferon-gamma; Interleukin-4; Lung; Male; Pulmonary Fibrosis; Quartz; Rats; Rats, Wistar; Silicosis; Transforming Growth Factor beta | 2005 |
Growth regulation of the rat mandibular condyle and femoral head by transforming growth factor-{beta}1, fibroblast growth factor-2 and insulin-like growth factor-I.
Topics: Animals; Animals, Newborn; Cell Proliferation; Chondrocytes; Collagen; DNA; Drug Interactions; Extracellular Matrix; Femur Head; Fibroblast Growth Factor 2; Glycosaminoglycans; Hydroxyproline; Insulin-Like Growth Factor I; Mandibular Condyle; Rats; Rats, Wistar; Tissue Culture Techniques; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
FTY720, an immunosuppressant, attenuates chronic pancreatitis in rats by suppressing T-cell infiltration.
Topics: Animals; Body Weight; Fingolimod Hydrochloride; Hydroxyproline; Immunosuppressive Agents; Interferon-gamma; Male; Organ Size; Pancreas; Pancreatitis, Chronic; Peroxidase; Propylene Glycols; Rats; Rats, Wistar; RNA, Messenger; Sphingosine; T-Lymphocytes; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Comparing study of the effect of nanosized silicon dioxide and microsized silicon dioxide on fibrogenesis in rats.
Topics: Animals; Female; Hydroxyproline; Image Processing, Computer-Assisted; Immunoenzyme Techniques; Inhalation Exposure; Interleukin-4; Intubation, Intratracheal; Male; Microchemistry; Nanostructures; Particle Size; Pulmonary Fibrosis; Rats; Rats, Wistar; Silicon Dioxide; Silicosis; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
The effect of an angiotensin converting enzyme inhibitor on intestinal wound healing.
Topics: Anastomosis, Surgical; Angiotensin-Converting Enzyme Inhibitors; Animals; Dose-Response Relationship, Drug; Hydroxyproline; Ileum; Lisinopril; Male; Models, Animal; Rats; Rats, Wistar; Tensile Strength; Transforming Growth Factor beta; Transforming Growth Factor beta1; Wound Healing | 2005 |
A novel nonsteroidal antifibrotic oligo decoy containing the TGF-beta element found in the COL1A1 gene which regulates murine schistosomiasis liver fibrosis.
Topics: Animals; Collagen; Collagen Type I; Collagen Type I, alpha 1 Chain; Consensus Sequence; DNA; Female; Fibroblasts; Granuloma; Hydroxyproline; Liver; Liver Cirrhosis; Liver Diseases; Mice; Mice, Inbred C57BL; Mutation; Myocytes, Smooth Muscle; Oligodeoxyribonucleotides; Oligonucleotides; Schistosomiasis mansoni; Sequence Homology, Nucleic Acid; Signal Transduction; Tissue Inhibitor of Metalloproteinase-1; Transfection; Transforming Growth Factor beta | 2005 |
Taurine inhibits oxidative damage and prevents fibrosis in carbon tetrachloride-induced hepatic fibrosis.
Topics: Actins; Animals; Carbon Tetrachloride; Cells, Cultured; Dose-Response Relationship, Drug; Hydroxyproline; Immunohistochemistry; Lipid Peroxides; Liver; Liver Cirrhosis, Experimental; Male; Myocytes, Smooth Muscle; Osmolar Concentration; Oxidative Stress; Rats; Rats, Sprague-Dawley; RNA, Messenger; Taurine; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Chinese medicine compound Changtong oral liquid on postoperative intestinal adhesions.
Topics: Administration, Oral; Animals; Drugs, Chinese Herbal; Female; Hydroxyproline; Male; Peritoneum; Postoperative Complications; Rabbits; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms; Tissue Adhesions; Tissue Plasminogen Activator; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Effects of T-lymphocyte depletion on muscle fibrosis in the mdx mouse.
Topics: Animals; Connective Tissue; Fibrosis; Flow Cytometry; Hydroxyproline; Lymphocyte Depletion; Mice; Mice, Inbred mdx; Muscle, Skeletal; Muscular Dystrophy, Animal; T-Lymphocytes; Thymectomy; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
[Effects of salvianolic acid B on expressions of TGF-beta1 and its receptors in liver of rats with dimethylnitrosamine-induced hepatic fibrosis].
Topics: Animals; Benzofurans; Collagen Type I; Dimethylnitrosamine; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Male; Protein Serine-Threonine Kinases; Random Allocation; Rats; Rats, Wistar; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
L-arginine improves wound healing after trauma-hemorrhage by increasing collagen synthesis.
Topics: Analysis of Variance; Animals; Arginine; Blotting, Western; Chromatography, High Pressure Liquid; Collagen; Hemorrhage; Hydroxyproline; Male; Mice; Mice, Inbred C3H; Random Allocation; Transforming Growth Factor beta; Wound Healing; Wounds and Injuries | 2005 |
Transforming growth factor-beta1 upregulation is independent of angiotensin in paraquat-induced lung fibrosis.
Topics: Actins; Angiotensin II; Animals; Collagen Type I; Collagen Type III; Disease Models, Animal; Hydroxyproline; Lung; Male; Microscopy, Polarization; Paraquat; Peptidyl-Dipeptidase A; Proto-Oncogene Proteins c-myc; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors; Toxicity Tests; Transforming Growth Factor beta; Transforming Growth Factor beta1; Up-Regulation | 2005 |
Natural killer T (NKT) cells attenuate bleomycin-induced pulmonary fibrosis by producing interferon-gamma.
Topics: Adoptive Transfer; Animals; Bleomycin; Body Weight; Cells, Cultured; Disease Models, Animal; Hydroxyproline; Interferon-gamma; Killer Cells, Natural; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pulmonary Fibrosis; T-Lymphocyte Subsets; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Losartan attenuates bleomycin-induced pulmonary fibrosis in rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antibiotics, Antineoplastic; Bleomycin; Body Weight; Glucocorticoids; Hydroxyproline; Losartan; Lung; Male; Malondialdehyde; Prednisone; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Transforming Growth Factor beta; Transforming Growth Factor beta1; Weight Gain | 2006 |
EM703 improves bleomycin-induced pulmonary fibrosis in mice by the inhibition of TGF-beta signaling in lung fibroblasts.
Topics: Animals; Anti-Inflammatory Agents; Base Sequence; Bleomycin; Cell Line; Cell Proliferation; Collagen; Dose-Response Relationship, Drug; Erythromycin; Fibroblasts; Gene Expression Regulation; Hydroxyproline; Lung; Male; Mice; Mice, Inbred ICR; Molecular Sequence Data; Pulmonary Fibrosis; Smad2 Protein; Smad3 Protein; Smad4 Protein; Transforming Growth Factor beta | 2006 |
Feitai, a Chinese herbal medicine, reduces transforming growth factor-beta1 and monocyte chemoattractant protein-1 expression in bleomycin-induced lung fibrosis in mice.
Topics: Animals; Anti-Bacterial Agents; Bleomycin; Cell Differentiation; Chemokine CCL2; Drugs, Chinese Herbal; Female; Fibroblasts; Hydroxyproline; Immunohistochemistry; Lung; Mice; Mice, Inbred C57BL; Peroxidase; Pulmonary Fibrosis; Reverse Transcriptase Polymerase Chain Reaction; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Combination of pre-operative radiotherapy and surgery suppresses local accumulation of collagen and TGF-beta1 in rats.
Topics: Animals; Collagen; Combined Modality Therapy; Disease Models, Animal; Hydroxyproline; Laparotomy; Male; Polytetrafluoroethylene; Postoperative Complications; Preoperative Care; Radiation Injuries, Experimental; Radiotherapy; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Wound Healing | 2006 |
Study of the efficacy of Coated VICRYL Plus Antibacterial suture (coated Polyglactin 910 suture with Triclosan) in two animal models of general surgery.
Topics: Anastomosis, Surgical; Animals; Anti-Infective Agents, Local; Antigens, CD; Bacterial Infections; Colony Count, Microbial; Hydroxyproline; Models, Animal; NF-kappa B; Nitric Oxide Synthase Type II; Peroxidase; Polyglactin 910; Superoxides; Surgical Wound Infection; Suture Techniques; Sutures; Swine; Swine, Miniature; Transforming Growth Factor beta; Triclosan; Tumor Necrosis Factor-alpha; Wound Healing | 2007 |
Pentoxifylline fails to attenuate fibrosis in dystrophic (mdx) diaphragm muscle.
Topics: Animals; Collagen Type I; Collagen Type III; Diaphragm; Disease Models, Animal; Enzyme Inhibitors; Fibrosis; Hydroxyproline; Male; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscle Contraction; Muscular Dystrophy, Animal; Muscular Dystrophy, Duchenne; Pentoxifylline; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1; Treatment Failure | 2006 |
Mycophenolate mofetil impairs the integrity of colonic anastomosis.
Topics: Anastomosis, Surgical; Animals; Colon; Fibroblasts; Hydroxyproline; Immunohistochemistry; Immunosuppressive Agents; Inflammation; Macrophages; Male; Mycophenolic Acid; Pressure; Rats; Rats, Wistar; Rupture; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Wound Healing | 2006 |
S-allyl cysteine attenuated CCl4-induced oxidative stress and pulmonary fibrosis in rats.
Topics: Animals; Bronchoalveolar Lavage Fluid; Carbon Tetrachloride; Cysteine; Enzyme Precursors; Glutathione; Hydroxyproline; Liver; Lung; Male; Matrix Metalloproteinase 9; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Pulmonary Fibrosis; Rats; Rats, Wistar; Reactive Oxygen Species; Sulfhydryl Compounds; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2006 |
Angelica sinensis down-regulates hydroxyproline and Tgfb1 and provides protection in mice with radiation-induced pulmonary fibrosis.
Topics: Angelica sinensis; Animals; Down-Regulation; Drugs, Chinese Herbal; Female; Hydroxyproline; Lung; Mice; Mice, Inbred C57BL; Radiation Pneumonitis; Radiation-Protective Agents; Transforming Growth Factor beta; Transforming Growth Factor beta1; Treatment Outcome | 2006 |
Filtrate of fermented mycelia from Antrodia camphorata reduces liver fibrosis induced by carbon tetrachloride in rats.
Topics: Animals; Base Sequence; Carbon Tetrachloride; Collagen Type I; Fermentation; Hydroxyproline; Liver Cirrhosis; Male; Malondialdehyde; Polyporales; Rats; Rats, Wistar; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2006 |
Age-dependent effect of myostatin blockade on disease severity in a murine model of limb-girdle muscular dystrophy.
Topics: Aging; Animals; Body Weight; Cobra Cardiotoxin Proteins; Disease Models, Animal; Fibrosis; Gene Deletion; Genotype; Hydroxyproline; Mice; Mice, Transgenic; Muscular Dystrophies, Limb-Girdle; Myostatin; Time Factors; Transforming Growth Factor beta | 2006 |
Anti-fibrogenic function of angiotensin II type 2 receptor in CCl4-induced liver fibrosis.
Topics: Animals; Carbon Tetrachloride; Gene Expression Regulation; Hydroxyproline; Inflammation; Liver Cirrhosis; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Thiobarbituric Acid Reactive Substances; Transforming Growth Factor beta | 2006 |
Control of virus reactivation arrests pulmonary herpesvirus-induced fibrosis in IFN-gamma receptor-deficient mice.
Topics: Animals; Antigens, Viral; Arginase; beta-N-Acetylhexosaminidases; Biomarkers; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Disease Progression; Fluorescent Antibody Technique, Indirect; Gene Expression Regulation, Viral; Herpesviridae Infections; Hydroxyproline; Immunoassay; Intercellular Signaling Peptides and Proteins; Interferon gamma Receptor; Lectins; Mice; Nerve Growth Factor; Proteins; Pulmonary Fibrosis; Receptors, Interferon; Reverse Transcriptase Polymerase Chain Reaction; Rhadinovirus; RNA, Viral; Transforming Growth Factor beta; Tumor Virus Infections; Vascular Endothelial Growth Factor A; Viral Envelope Proteins; Virus Activation | 2007 |
[Inhibitory effect of angiotensin blockade on hepatic fibrosis in common bile duct-ligated rats].
Topics: Actins; Angiotensin II Type 1 Receptor Blockers; Animals; Bile Ducts; Captopril; Fibrosis; Hydroxyproline; Ligation; Liver; Liver Cirrhosis, Experimental; Losartan; Male; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta | 2007 |
Cysteinyl-leukotriene 1 receptor antagonist attenuates bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Cysteine; Disease Models, Animal; Hydroxyproline; Leukotriene Antagonists; Leukotrienes; Male; Mice; Mice, Inbred C57BL; Pulmonary Fibrosis; Receptors, Leukotriene; Transforming Growth Factor beta | 2007 |
The effect of immunosuppression on peritoneal adhesions formation after small bowel transplantation in rats.
Topics: Animals; Hydroxyproline; Immunosuppression Therapy; Intestine, Small; Male; Postoperative Complications; Rats; Rats, Inbred Lew; RNA, Messenger; Tissue Adhesions; Transforming Growth Factor beta; Transplantation, Homologous | 2007 |
Post-translational modifications of collagen upon BMP-induced osteoblast differentiation.
Topics: Animals; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Cell Differentiation; Cell Line; Collagen Type I; Humans; Hydroxylysine; Hydroxyproline; Isoenzymes; Mice; Myoblasts; Osteoblasts; Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase; Protein Processing, Post-Translational; Protein-Lysine 6-Oxidase; RNA Splicing; RNA, Messenger; Transforming Growth Factor beta | 2007 |
Connective tissue alterations in women with pelvic organ prolapse and urinary incontinence.
Topics: Biopsy; Collagen; Connective Tissue; Female; Glycosaminoglycans; Hexosaminidases; Humans; Hydroxyproline; Leptin; Middle Aged; Statistics, Nonparametric; Transforming Growth Factor beta; Urinary Incontinence; Uterine Prolapse | 2007 |
In vivo investigations on anti-fibrotic potential of proteasome inhibition in lung and skin fibrosis.
Topics: Animals; Bleomycin; Boronic Acids; Bortezomib; Cells, Cultured; Collagen Type I; Fibrosis; Hydroxyproline; Leupeptins; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Proteasome Inhibitors; Protein Serine-Threonine Kinases; Pulmonary Fibrosis; Pyrazines; Scleroderma, Systemic; Signal Transduction; Skin; Transforming Growth Factor beta | 2008 |
[Serum hyaluronic acid level: correlation with quantitative measurement of hepatic fibrosis in a cirrhotic rat model].
Topics: Animals; Bile Ducts; Biomarkers; Collagen; Hyaluronic Acid; Hydroxyproline; Ligation; Liver; Liver Cirrhosis, Experimental; Male; Models, Animal; Procollagen; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sickness Impact Profile; Transforming Growth Factor beta | 2008 |
Platelets contribute to the reduction of liver fibrosis in mice.
Topics: Animals; Blood Platelets; Carbon Tetrachloride; Cell Proliferation; Disease Models, Animal; Female; Gene Expression Regulation; Hydroxyproline; Liver; Liver Cirrhosis; Liver Regeneration; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitotic Index; Phosphorylation; Platelet Count; Proto-Oncogene Proteins c-akt; RNA, Messenger; Splenectomy; Thrombocytosis; Thrombopoietin; Transforming Growth Factor beta | 2009 |
Trolox down-regulates transforming growth factor-beta and prevents experimental cirrhosis.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Blotting, Western; Carbon Tetrachloride; Chromans; Down-Regulation; gamma-Glutamyltransferase; Glutathione; Glycogen; Hydroxyproline; Lipid Peroxidation; Liver Cirrhosis, Experimental; Male; Rats; Rats, Wistar; Transforming Growth Factor beta | 2008 |
[Smad7 instead of Smad6 blocks epithelial-mesenchymal transition induced by TGF-beta in human renal proximal tubule epithelial cells].
Topics: Actins; Blotting, Western; Cadherins; Cell Differentiation; Cell Line; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Humans; Hydroxyproline; Kidney Tubules, Proximal; Mesoderm; Smad2 Protein; Smad6 Protein; Smad7 Protein; Transforming Growth Factor beta | 2008 |
Effect of praziquantel treatment on the expression of matrix metalloproteinases in relation to tissue resorption during fibrosis in hamsters with acute and chronic Opisthorchis viverrini infection.
Topics: Animals; Collagen; Cricetinae; Gene Expression Profiling; Hydroxyproline; Liver; Liver Cirrhosis; Male; Matrix Metalloproteinases; Opisthorchiasis; Opisthorchis; Praziquantel; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2009 |
Blockade of advanced glycation end product formation attenuates bleomycin-induced pulmonary fibrosis in rats.
Topics: Animals; Antimetabolites, Antineoplastic; Bleomycin; Blotting, Western; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Guanidines; HSP47 Heat-Shock Proteins; Hydroxyproline; Lung; Male; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta | 2009 |
Urotensin II modulates hepatic fibrosis and portal hemodynamic alterations in rats.
Topics: Animals; Dose-Response Relationship, Drug; Hydroxyproline; Hypertension, Portal; Infusion Pumps, Implantable; Infusions, Subcutaneous; Liver; Liver Cirrhosis; Male; Portal Pressure; Portal System; Proto-Oncogene Proteins c-sis; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Transforming Growth Factor beta; Up-Regulation; Urotensins | 2009 |
Extracorporeal photopheresis in a rat model of pulmonary fibrosis.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Gene Expression Regulation; Hydroxyproline; Interferon-gamma; Interleukin-10; Lung; Photopheresis; Pulmonary Fibrosis; Rats; Rats, Inbred Lew; Severity of Illness Index; Time Factors; Transforming Growth Factor beta | 2009 |
Adult equine bone marrow stromal cells produce a cartilage-like ECM mechanically superior to animal-matched adult chondrocytes.
Topics: Aggrecans; Animals; Bone Marrow Cells; Cartilage; Cell Survival; Chondrocytes; Chromatography, Gel; Extracellular Matrix; Horses; Hydrogels; Hydroxyproline; Male; Microscopy, Atomic Force; Stress, Mechanical; Tissue Engineering; Transforming Growth Factor beta | 2010 |
The role of the receptor for advanced glycation end-products in a murine model of silicosis.
Topics: Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Gene Expression Regulation; Glycation End Products, Advanced; Hydroxyproline; Inflammation; Lung; Mice; Mice, Inbred C57BL; Mice, Knockout; Pulmonary Fibrosis; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Silicosis; Transforming Growth Factor beta | 2010 |
Reduction of periductal fibrosis in liver fluke-infected hamsters after long-term curcumin treatment.
Topics: Actins; Animals; Collagen; Cricetinae; Curcumin; Drug Administration Schedule; Gene Expression Regulation; Hydroxyproline; Inflammation; Interleukin-1beta; Liver Cirrhosis; Liver Cirrhosis, Experimental; Male; Matrix Metalloproteinases; Opisthorchiasis; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Tissue Inhibitor of Metalloproteinases; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2010 |
Induction of EMT-like phenotypes by an active metabolite of leflunomide and its contribution to pulmonary fibrosis.
Topics: Aniline Compounds; Animals; Bleomycin; Cells, Cultured; Crotonates; Dihydroorotate Dehydrogenase; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; Homeodomain Proteins; Humans; Hydroxybutyrates; Hydroxyproline; Mice; Nitriles; Oxidoreductases Acting on CH-CH Group Donors; Phenotype; Pulmonary Fibrosis; Rats; Receptors, Notch; Repressor Proteins; RNA Interference; RNA, Small Interfering; Signal Transduction; Toluidines; Transforming Growth Factor beta; Uridine; Zinc Finger E-box Binding Homeobox 2 | 2010 |
Radiation-induced liver fibrosis is mitigated by gene therapy inhibiting transforming growth factor-β signaling in the rat.
Topics: Adenoviridae; Animals; Genetic Therapy; Genetic Vectors; Hepatic Stellate Cells; Hyaluronic Acid; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Male; Oxidative Stress; Protein Serine-Threonine Kinases; Radiation Injuries, Experimental; Rats; Rats, Sprague-Dawley; Receptor, Transforming Growth Factor-beta Type II; Receptors, IgG; Receptors, Transforming Growth Factor beta; Recombinant Proteins; Transforming Growth Factor beta; Viral Plaque Assay | 2010 |
N-methyl-4-isoleucine cyclosporine attenuates CCl -induced liver fibrosis in rats by interacting with cyclophilin B and D.
Topics: Actins; Alanine Transaminase; Analysis of Variance; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Cell Line; Collagen Type III; Cyclophilins; Cyclosporine; Cytoprotection; Dose-Response Relationship, Drug; Hepatic Stellate Cells; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Male; Matrix Metalloproteinase 13; Peptidyl-Prolyl Isomerase F; Rats; Rats, Wistar; RNA Interference; RNA, Messenger; Serum Albumin; Time Factors; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta | 2011 |
Inhibiting TGF-β activity improves respiratory function in mdx mice.
Topics: Animals; Biomarkers; Body Weight; Cell Adhesion Molecules; Creatine Kinase; Diaphragm; Dose-Response Relationship, Drug; Enalapril; Gene Expression Regulation; Hand Strength; Hydroxyproline; Inflammation; Losartan; Mice; Mice, Inbred mdx; Muscle Fibers, Skeletal; Myogenin; Organ Size; Respiration; Respiratory Function Tests; RNA, Messenger; Transforming Growth Factor beta | 2011 |
The use of pentoxifylline as adjuvant therapy with praziquantel downregulates profibrogenic cytokines, collagen deposition and oxidative stress in experimental schistosomiasis mansoni.
Topics: Animals; Collagen; Cytokines; Down-Regulation; Drug Therapy, Combination; Free Radical Scavengers; Hydroxyproline; Lipid Peroxidation; Liver; Male; Matrix Metalloproteinase 2; Mice; Oxidative Stress; Pentoxifylline; Praziquantel; Random Allocation; Schistosomiasis mansoni; Schistosomicides; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2011 |
Protease-activated receptor 2 promotes experimental liver fibrosis in mice and activates human hepatic stellate cells.
Topics: Animals; Carbon Tetrachloride; Cell Proliferation; Cells, Cultured; Collagen; Cytokines; Disease Models, Animal; Disease Progression; Hepatic Stellate Cells; Humans; Hydroxyproline; In Vitro Techniques; Liver; Liver Cirrhosis; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligopeptides; Receptor, PAR-2; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta | 2012 |
Trolox mitigates fibrosis in a bile duct ligation model.
Topics: Administration, Oral; Alanine Transaminase; Animals; Antioxidants; Bile Ducts; Blotting, Western; Chromans; Collagen; Glutathione; Hydroxyproline; Interleukin-10; Interleukin-6; Lipid Peroxidation; Liver Cirrhosis, Experimental; Male; Oxidative Stress; Rats; Rats, Wistar; Transforming Growth Factor beta | 2013 |
The role of all-trans retinoic acid in bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; CD4-Positive T-Lymphocytes; Cell Count; Disease Models, Animal; Drug Therapy, Combination; Gene Expression; Hydroxyproline; Interleukins; Lung; Male; Mice; Mice, Inbred C57BL; Pulmonary Fibrosis; T-Lymphocytes, Regulatory; Th17 Cells; Transforming Growth Factor beta; Tretinoin | 2012 |
Protective effect of sodium ferulate on acetaldehyde-treated precision-cut rat liver slices.
Topics: Acetaldehyde; Actins; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Collagen; Coumaric Acids; Ethanol; Hepatic Stellate Cells; Hydroxyproline; Liver; Male; Malondialdehyde; Matrix Metalloproteinase 1; Oxidative Stress; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta | 2012 |
Aqueous extract of Artemisia iwayomogi Kitamura attenuates cholestatic liver fibrosis in a rat model of bile duct ligation.
Topics: Actins; Animals; Antioxidants; Artemisia; Bile Ducts; Cholestasis; Collagen Type I; Collagen Type I, alpha 1 Chain; Dose-Response Relationship, Drug; Gene Expression; Hydroxyproline; Ligation; Liver Cirrhosis; Male; Malondialdehyde; Molecular Structure; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; Plant Extracts; Platelet-Derived Growth Factor; Rats; Rats, Sprague-Dawley; Scopoletin; Specific Pathogen-Free Organisms; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2012 |
Long-acting human serum albumin-thioredoxin fusion protein suppresses bleomycin-induced pulmonary fibrosis progression.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Blotting, Western; Bronchoalveolar Lavage Fluid; Disease Progression; Hydroxyproline; Interleukin-6; Lung; Macrophage Migration-Inhibitory Factors; Macrophages; Malondialdehyde; Mice; Neutrophils; Pulmonary Fibrosis; Reactive Oxygen Species; Recombinant Fusion Proteins; Serum Albumin; Thioredoxins; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2013 |
Berberine attenuates bleomycin induced pulmonary toxicity and fibrosis via suppressing NF-κB dependant TGF-β activation: a biphasic experimental study.
Topics: Animals; Antimetabolites; Berberine; Bleomycin; Blotting, Western; Bronchoalveolar Lavage Fluid; Collagen; Histamine Release; Hydroxyproline; Immunohistochemistry; Lung Diseases; Male; Malondialdehyde; Microscopy, Confocal; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide Synthase Type II; Nitrites; Oxidative Stress; Peroxidase; Pulmonary Fibrosis; Rats; Rats, Wistar; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Weight Gain | 2013 |
Camel whey protein enhances diabetic wound healing in a streptozotocin-induced diabetic mouse model: the critical role of β-Defensin-1, -2 and -3.
Topics: Animals; Anti-Infective Agents; beta-Defensins; Biomarkers; Camelus; Collagen; Diabetes Mellitus, Experimental; Dietary Supplements; Female; Free Radicals; Gene Expression; Hydroxyproline; Interleukin-6; Male; Mice; Milk; Milk Proteins; Skin; Streptozocin; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Whey Proteins; Wound Healing | 2013 |
Bone morphogenetic protein-7 inhibits silica-induced pulmonary fibrosis in rats.
Topics: Animals; Bone Morphogenetic Protein 7; Dust; Humans; Hydroxyproline; Lung; Male; Pulmonary Fibrosis; Random Allocation; Rats; Rats, Wistar; Recombinant Proteins; Signal Transduction; Silicon Dioxide; Smad Proteins; Transforming Growth Factor beta | 2013 |
Multitargeted inhibition of hepatic fibrosis in chronic iron-overloaded mice by Salvia miltiorrhiza.
Topics: Animals; Collagen Type I; Collagen Type III; Down-Regulation; Hydroxyproline; Interleukin-1alpha; Iron Overload; Liver; Liver Cirrhosis; Male; Mice; Oxidative Stress; Plant Extracts; Random Allocation; Salvia miltiorrhiza; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Up-Regulation | 2013 |
Recombinant bovine pancreatic trypsin inhibitor protects the liver from carbon tetrachloride-induced chronic injury in rats.
Topics: Alanine Transaminase; Animals; Aprotinin; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury, Chronic; Cytoprotection; Disease Models, Animal; Fatty Liver; Hydroxyproline; Inflammation Mediators; Interleukin-1beta; Liver; Liver Cirrhosis, Experimental; Male; Necrosis; Protective Agents; Rats; Rats, Wistar; Recombinant Proteins; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Transforming Growth Factor beta | 2013 |
Human platelets inhibit liver fibrosis in severe combined immunodeficiency mice.
Topics: Actins; Animals; Biomarkers; Carbon Tetrachloride; Caspase 3; Hepatocyte Growth Factor; Hepatocytes; Humans; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Male; Matrix Metalloproteinase 9; Mice; Mice, SCID; Phosphorylation; Platelet Transfusion; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-met; Signal Transduction; Smad3 Protein; Time Factors; Transforming Growth Factor beta | 2013 |
Activated alveolar epithelial cells initiate fibrosis through autocrine and paracrine secretion of connective tissue growth factor.
Topics: Animals; Antibiotics, Antineoplastic; Autocrine Communication; Bleomycin; Blotting, Western; Bronchoalveolar Lavage; Connective Tissue Growth Factor; Culture Media, Conditioned; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Extracellular Matrix Proteins; Fluorescent Antibody Technique; Hydroxyproline; Mice; Mice, Inbred C57BL; Mice, Knockout; Paracrine Communication; Pulmonary Alveoli; Pulmonary Fibrosis; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Transforming Growth Factor beta | 2014 |
The effect of adipose stem cell therapy on pulmonary fibrosis induced by repetitive intratracheal bleomycin in mice.
Topics: Adipose Tissue; Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Hydroxyproline; In Situ Nick-End Labeling; Lung; Male; Mesenchymal Stem Cell Transplantation; Mice; Mice, Inbred C57BL; Pulmonary Fibrosis; Transforming Growth Factor beta | 2014 |
The effect of recombinant sTGFβ1RII and sIL13Rα2 receptor proteins on schistosomiasis japonica, hepatic fibrosis and signal transduction in a mouse model of schistosome disease.
Topics: Animals; Disease Models, Animal; Eukaryotic Initiation Factors; Extracellular Matrix Proteins; Female; Granuloma; Hydroxyproline; Interleukin-13; Interleukin-13 Receptor alpha2 Subunit; Intracellular Signaling Peptides and Proteins; Liver; Liver Cirrhosis; Liver Diseases; Lung; Mice; Mice, Inbred BALB C; Pulmonary Fibrosis; Random Allocation; Real-Time Polymerase Chain Reaction; Recombinant Proteins; Schistosomiasis japonica; Signal Transduction; Smad Proteins; STAT6 Transcription Factor; Transforming Growth Factor beta | 2014 |
Study on salvianolic acid B in the reduction of epidural fibrosis in laminectomy rats.
Topics: Animals; Anti-Inflammatory Agents; Benzofurans; Cell Proliferation; Cicatrix; Double-Blind Method; Drugs, Chinese Herbal; Epidural Space; Fibroblasts; Fibrosis; Hydroxyproline; Interleukin-6; Laminectomy; Male; Rats, Wistar; Tissue Adhesions; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A | 2014 |
Chunggan extract, a traditional herbal formula, ameliorated alcohol-induced hepatic injury in rat model.
Topics: Animals; Cell Line; Collagen; Connective Tissue Growth Factor; Cytokines; Disease Models, Animal; Drugs, Chinese Herbal; Gene Expression Regulation; Hepatocytes; Hydroxyproline; Liver; Liver Diseases, Alcoholic; Male; Malondialdehyde; Phytotherapy; Plants, Medicinal; Protective Agents; Proto-Oncogene Proteins c-sis; Rats, Sprague-Dawley; RNA, Messenger; Time Factors; Transforming Growth Factor beta | 2014 |
Naja naja atra venom ameliorates pulmonary fibrosis by inhibiting inflammatory response and oxidative stress.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Bleomycin; Elapid Venoms; Elapidae; Female; Fibrosis; Hydroxyproline; Inflammation; Interleukin-1beta; Lung; Male; Mice; NF-kappa B; Oxidative Stress; Pulmonary Fibrosis; Rats, Sprague-Dawley; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2014 |
Inhibition of transforming growth factor-β via the activin receptor-like kinase-5 inhibitor attenuates pulmonary fibrosis.
Topics: Actins; Animals; Benzamides; Cell Line; Cell Proliferation; Cell Survival; Dioxoles; Disease Models, Animal; Female; Fibroblasts; Humans; Hydroxyproline; Mice; Protein Serine-Threonine Kinases; Pulmonary Fibrosis; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Transforming Growth Factor beta | 2015 |
Smoking p66Shc knocked out mice develop respiratory bronchiolitis with fibrosis but not emphysema.
Topics: Animals; Apoptosis; Arginase; Bronchiolitis; Chitinases; Desmosine; Fibrosis; Hydroxyproline; Interleukin-13; Interleukin-4; Lung; Macrophages; Mice; Mice, Knockout; Oxidative Stress; Oxidoreductases; Pulmonary Emphysema; Shc Signaling Adaptor Proteins; Smoking; Src Homology 2 Domain-Containing, Transforming Protein 1; Transforming Growth Factor beta; Tumor Suppressor Protein p53 | 2015 |
Cyclophosphamide Combined with Bone Marrow Mesenchymal Stromal Cells Protects against Bleomycin-induced Lung Fibrosis in Mice.
Topics: Animals; Biological Assay; Bleomycin; Cell Differentiation; Chemokine CXCL12; Collagen; Combined Modality Therapy; Cyclophosphamide; Female; Gene Expression Regulation; Hydroxyproline; Immunohistochemistry; Lung; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Platelet-Derived Growth Factor; Pulmonary Fibrosis; RNA, Messenger; Transforming Growth Factor beta | 2015 |
Theophylline, an old drug with multi-faceted effects: Its potential benefits in immunological liver injury in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Caspase 3; Chemical and Drug Induced Liver Injury; Drug Evaluation, Preclinical; Hydroxyproline; Interferon-alpha; Liver; Liver Cirrhosis; Male; Portal Pressure; Rats, Wistar; Theophylline; Transforming Growth Factor beta | 2015 |
Secretoglobin 3A2 Exhibits Anti-Fibrotic Activity in Bleomycin-Induced Pulmonary Fibrosis Model Mice.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Collagen; Collectins; Cytokines; Disease Models, Animal; Hydroxyproline; Inflammation; Interleukin-4; Lung; Mice; Mice, Inbred C57BL; Mice, Knockout; Pulmonary Fibrosis; Real-Time Polymerase Chain Reaction; RNA, Messenger; Secretoglobins; Severity of Illness Index; Transforming Growth Factor beta | 2015 |
Fibroblast growth factor 21 attenuates hepatic fibrogenesis through TGF-β/smad2/3 and NF-κB signaling pathways.
Topics: Actins; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Collagen Type I; Dimethylnitrosamine; Down-Regulation; Fibroblast Growth Factors; Hepatic Stellate Cells; Hydroxyproline; Liver; Liver Cirrhosis; Male; Mice; Mice, Inbred ICR; NF-kappa B; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta | 2016 |
Ameliorative effects of Xue-Fu-Zhu-Yu decoction, Tian-Ma-Gou-Teng-Yin and Wen-Dan decoction on myocardial fibrosis in a hypertensive rat mode.
Topics: Animals; Blood Pressure; Collagen; Disease Models, Animal; Drugs, Chinese Herbal; Endomyocardial Fibrosis; Hydroxyproline; Hypertension; Male; Rats; Rats, Inbred WKY; Transforming Growth Factor beta | 2016 |
Secretory leukocyte protease inhibitor gene deletion alters bleomycin-induced lung injury, but not development of pulmonary fibrosis.
Topics: Animals; Bleomycin; Collagen; Gene Deletion; Hydroxyproline; Idiopathic Pulmonary Fibrosis; Lung; Lung Injury; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; RNA, Messenger; Secretory Leukocyte Peptidase Inhibitor; Transforming Growth Factor beta | 2016 |
HIF-1 α as a Key Factor in Bile Duct Ligation-Induced Liver Fibrosis in Rats.
Topics: Animals; Bile Ducts; Disease Models, Animal; Humans; Hydroxyproline; Hypoxia-Inducible Factor 1, alpha Subunit; Integrin beta1; Ligation; Liver; Liver Cirrhosis; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; NF-kappa B; Rats; Rats, Wistar; Signal Transduction; Transforming Growth Factor beta; Up-Regulation | 2017 |
Effects of platelet rich plasma on fascial healing in rats with fecal peritonitis
Topics: Animals; Collagen; Endopeptidases; Fascia; Gelatinases; Hydroxyproline; Membrane Proteins; Models, Animal; Neovascularization, Physiologic; Peritonitis; Platelet-Rich Plasma; Random Allocation; Rats, Wistar; Serine Endopeptidases; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Wound Healing | 2016 |
Mammalian Target of Rapamycin Inhibition With Rapamycin Mitigates Radiation-Induced Pulmonary Fibrosis in a Murine Model.
Topics: Alveolar Epithelial Cells; Animals; beta-Galactosidase; Cellular Senescence; Extracellular Matrix; Female; Hydroxyproline; Interleukin-1beta; Lung; Macrophages; Mice; Mice, Inbred C57BL; Radiation Pneumonitis; Radiation Tolerance; Radiation-Protective Agents; Sirolimus; TOR Serine-Threonine Kinases; Transforming Growth Factor beta | 2016 |
HYDAMTIQ, a selective PARP-1 inhibitor, improves bleomycin-induced lung fibrosis by dampening the TGF-β/SMAD signalling pathway.
Topics: Actins; Animals; Biomarkers; Bleomycin; Fibroblasts; Hydroxyproline; Inflammation Mediators; Isoquinolines; Lung; Male; Mice, Inbred C57BL; Oxidative Stress; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Pulmonary Fibrosis; Signal Transduction; Smad Proteins; Thiophenes; Transforming Growth Factor beta | 2017 |
Regression of fibrosis/cirrhosis by Glycine propionyl-l-carnitine treatment in d-Galactosamine induced chronic liver damage.
Topics: Actins; Animals; Body Weight; Carnitine; Chronic Disease; Collagen Type I; Galactosamine; Gene Expression Regulation; Glycine; Hydroxyproline; In Situ Nick-End Labeling; Interleukin-6; Liver; Liver Cirrhosis; Male; Oxidative Stress; Rats, Wistar; RNA, Messenger; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Tyrosine | 2016 |
Novel form of miR-29b suppresses bleomycin-induced pulmonary fibrosis.
Topics: Administration, Inhalation; Animals; Bleomycin; Fibroblasts; Hydroxyproline; Male; Mice; Mice, Inbred C57BL; MicroRNAs; NIH 3T3 Cells; Pulmonary Fibrosis; Signal Transduction; Toll-Like Receptors; Transforming Growth Factor beta | 2017 |
Endothelial cell-specific activation of transforming growth factor-β signaling in mice induces cutaneous, visceral, and microvascular fibrosis.
Topics: Animals; Endothelial Cells; Female; Fibrosis; Hydroxyproline; Immunohistochemistry; Lung; Male; Mice; Mice, Transgenic; Microscopy, Confocal; Organ Specificity; Signal Transduction; Tamoxifen; Transforming Growth Factor beta | 2017 |
Coffee consumption prevents fibrosis in a rat model that mimics secondary biliary cirrhosis in humans.
Topics: Actins; Animals; Antioxidants; Bile Ducts; Caffeine; Coffee; Connective Tissue Growth Factor; Disease Models, Animal; Fibrosis; Glutathione Peroxidase; Hepatic Stellate Cells; Hydroxyproline; Lipid Peroxidation; Liver; Liver Cirrhosis, Biliary; Male; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Transforming Growth Factor beta | 2017 |
Human placental mesenchymal stem cells of fetal origins-alleviated inflammation and fibrosis by attenuating MyD88 signaling in bleomycin-induced pulmonary fibrosis mice.
Topics: A549 Cells; Animals; Bleomycin; Cell Line; Female; Humans; Hydroxyproline; Inflammation; Interleukin-1beta; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; Myeloid Differentiation Factor 88; Placenta; Pregnancy; Pulmonary Fibrosis; Signal Transduction; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2017 |
Effects and Mechanisms of Total Flavonoids from Blumea balsamifera (L.) DC. on Skin Wound in Rats.
Topics: Animals; Anti-Inflammatory Agents; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Asteraceae; Cicatrix; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Flavonoids; Hydroxyproline; Neovascularization, Physiologic; Rats; Rats, Sprague-Dawley; Skin; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A | 2017 |
Pharmacological targeting of BET proteins attenuates radiation-induced lung fibrosis.
Topics: Animals; Azepines; Cell Line, Tumor; Cell Proliferation; Collagen Type I; Female; Fibroblasts; Gamma Rays; Gene Expression Regulation; Humans; Hydroxyproline; Lung; MCF-7 Cells; Molecular Targeted Therapy; NF-kappa B; Nuclear Proteins; Proteins; Proto-Oncogene Proteins c-myc; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Smad2 Protein; Smad3 Protein; Transcription Factors; Transforming Growth Factor beta; Triazoles | 2018 |
Renin-angiotensin system inhibition ameliorates CCl
Topics: Actins; Alanine Transaminase; alpha-Fetoproteins; Animals; Carbon Tetrachloride; Gene Expression Regulation; Hydroxyproline; Liver Cirrhosis; Male; Matrix Metalloproteinase 2; Mice; NF-kappa B; Renin-Angiotensin System; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2018 |
Thrombin and factor Xa link the coagulation system with liver fibrosis.
Topics: Actins; Animals; Antithrombins; Blood Coagulation; Cell Line; Cell Shape; Dabigatran; Disease Models, Animal; Factor Xa; Factor Xa Inhibitors; Gene Expression; Hepatic Stellate Cells; Humans; Hydroxyproline; Liver Cirrhosis; Male; Mice, Inbred C57BL; Procollagen; Receptor, PAR-1; Rivaroxaban; Thrombin; Transforming Growth Factor beta | 2018 |
[Effect and mechnism study of Shengjiyuhong cream on transdifferentiation and collagen production of normal human dermal fibroblasts].
Topics: Actins; Cell Transdifferentiation; Collagen; Fibroblasts; Humans; Hydroxyproline; RNA, Messenger; Signal Transduction; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta; Transforming Growth Factor beta1; Wound Healing | 2016 |
Therapeutic Effects of Human Umbilical Cord-Derived Mesenchymal Stem Cells on Canine Radiation-Induced Lung Injury.
Topics: Animals; Blood Gas Analysis; Disease Models, Animal; Dogs; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Hydroxyproline; Leukocytes; Lung; Lung Injury; Lymphocyte Count; Lymphocytes; Male; Mesenchymal Stem Cell Transplantation; Oxidative Stress; Radiation Injuries, Experimental; Random Allocation; Smad2 Protein; Smad3 Protein; Superoxide Dismutase; Time Factors; Transforming Growth Factor beta; Umbilical Cord | 2018 |
Sinapic acid ameliorates bleomycin-induced lung fibrosis in rats.
Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Bleomycin; Bronchoalveolar Lavage Fluid; Coumaric Acids; Disease Models, Animal; Heme Oxygenase-1; Hydroxyproline; Inflammation; Lung; Matrix Metalloproteinase 7; NF-E2-Related Factor 2; NF-kappa B; Organ Size; Oxidative Stress; Pulmonary Fibrosis; Rats, Sprague-Dawley; Transforming Growth Factor beta; Weight Gain | 2018 |
The anti-inflammatory and anti-fibrotic effects of tadalafil in thioacetamide-induced liver fibrosis in rats.
Topics: Actins; Animals; Anti-Inflammatory Agents; Biomarkers; Collagen Type I; Cytokines; Gene Expression; Hydroxyproline; Inflammation; Interleukin-10; Interleukin-1beta; Interleukin-6; Liver; Liver Cirrhosis; Male; Nitric Oxide; Rats; Rats, Wistar; Tadalafil; Thioacetamide; Transaminases; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2018 |
Locostatin Alleviates Liver Fibrosis Induced by Carbon Tetrachloride in Mice.
Topics: Actins; Animals; Carbon Tetrachloride; Cell Movement; Collagen Type I; Collagen Type II; E-Selectin; Hepatic Stellate Cells; Hydroxyproline; Liver Cirrhosis; Male; Matrix Metalloproteinase 13; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Oxazolidinones; Peroxidase; Phosphatidylethanolamine Binding Protein; Platelet-Derived Growth Factor; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Transforming Growth Factor beta | 2019 |
Mechanistic aspects of antifibrotic effects of honokiol in Con A-induced liver fibrosis in rats: Emphasis on TGF-β/SMAD/MAPK signaling pathways.
Topics: Actins; Animals; Biphenyl Compounds; Concanavalin A; Hydroxyproline; Inflammation; Lignans; Liver Cirrhosis; Male; Mitogen-Activated Protein Kinases; Oxidative Stress; Rats; Rats, Sprague-Dawley; Signal Transduction; Smad Proteins; Survival Analysis; Transforming Growth Factor beta | 2020 |
CREBH knockout accelerates hepatic fibrosis in mouse models of diet-induced nonalcoholic fatty liver disease.
Topics: Alanine Transaminase; Animals; Choline Deficiency; Cyclic AMP Response Element-Binding Protein; Diet, High-Fat; Fibroblast Growth Factors; Hydroxyproline; Lipids; Liver Cirrhosis; Male; Methionine; Mice; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Signal Transduction; Transforming Growth Factor beta | 2020 |
Anti-fibrotic effect of melittin on TRIM47 expression in human embryonic lung fibroblast through regulating TRIM47 pathway.
Topics: Actins; Carrier Proteins; Cell Proliferation; Connective Tissue Growth Factor; Fibroblasts; Fibrosis; Gene Expression Regulation; Humans; Hydroxyproline; Lung; Melitten; Neoplasm Proteins; Nuclear Proteins; Phosphorylation; Protein Phosphatase 2C; RNA Interference; RNA, Messenger; Signal Transduction; Smad Proteins; Transforming Growth Factor beta; Ubiquitination; Vimentin | 2020 |
Micellar Hyaluronidase and Spiperone as a Potential Treatment for Pulmonary Fibrosis.
Topics: Animals; Cell Differentiation; Collagen Type I; Hyaluronic Acid; Hyaluronoglucosaminidase; Hydroxyproline; Idiopathic Pulmonary Fibrosis; Inflammation; Interleukin-1beta; Keratins; Lung; Male; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Platelet Endothelial Cell Adhesion Molecule-1; Poloxamer; Receptors, IgG; Spiperone; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2021 |
Wound Healing Activity of
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Collagen Type I; Collagen Type I, alpha 1 Chain; Drug Delivery Systems; Emulsions; Hydroxyproline; Male; Opuntia; Plant Oils; Rats, Wistar; Seeds; Skin; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A; Wound Healing | 2021 |
Pulmonary delivery of a recombinant RAGE antagonist peptide derived from high-mobility group box-1 in a bleomycin-induced pulmonary fibrosis animal model.
Topics: Animals; Bleomycin; Collagen; Disease Models, Animal; Hydroxyproline; Lung; Mice; Mice, Inbred C57BL; Pulmonary Fibrosis; Receptor for Advanced Glycation End Products; Transforming Growth Factor beta | 2022 |
The combination of experimental periodontitis and oral microbiota from periodontitis patients aggravates liver fibrosis in mice.
Topics: Actins; Alanine Transaminase; Animals; Azo Compounds; Carbon Tetrachloride; Hydroxyproline; Liver Cirrhosis; Male; Methylene Blue; Mice; Microbiota; Periodontitis; RNA, Ribosomal, 16S; Transforming Growth Factor beta | 2022 |
Myostatin deficiency decreases cardiac extracellular matrix in pigs.
Topics: Animals; Collagen Type I; Extracellular Matrix; Female; Hydroxyproline; Male; Muscle, Skeletal; Myostatin; Proto-Oncogene Proteins c-akt; Swine; Transforming Growth Factor beta | 2022 |
Determination of the effectiveness of
Topics: Animals; Endothelial Growth Factors; Epidermal Growth Factor; Hydroxyproline; Male; Ointments; Phenytoin; Plant Extracts; Platelet-Derived Growth Factor; Rats; Rats, Wistar; Transforming Growth Factor beta; Transforming Growth Factors; Vascular Endothelial Growth Factor A; Wound Healing | 2022 |
Sunitinib displays pulmonary fibrosis in experimental rats: Role of IL-17A dependent pathway.
Topics: Animals; Collagen; Fibrosis; Hydroxyproline; Interleukin-17; Interleukin-6; Pulmonary Fibrosis; Rats; Rats, Wistar; Sunitinib; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2023 |