hydroxyproline has been researched along with sirolimus in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 9 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Böhm, GA; Khaw, LE; Leadlay, PF; Metcalfe, S; Staunton, J | 1 |
| Chambers, RC; Egan, JJ; Goldsack, NR; Hasleton, PS; Howell, DC; Laurent, GJ; Marshall, RP; Simler, NR | 1 |
| Michalski, S; Napirei, M; Schäffer, M; Schier, R; Traska, T; Viebahn, R | 1 |
| Beckert, S; Coerper, S; Königsrainer, A; Küper, MA; Mayer, P; Schölzl, N; Steurer, W; Traub, F; Weinreich, J | 1 |
| Miltyk, W; Palka, J; Prokop, I; Surazynski, A | 1 |
| Beckert, S; Coerper, S; Königsrainer, A; Königsrainer, I; Löb, S; Löffler, M; Weinreich, J; Zieker, D | 1 |
| de Man, BM; Hendriks, T; Lomme, RM; van der Vliet, JA; Willems, MC | 1 |
| Bridle, KR; Campbell, CM; Clouston, AD; Crawford, DH; de Guzman, CE; Jaskowski, LA; Nathan Subramaniam, V; Santrampurwala, N; Sobbe, AL | 1 |
| Li, X; Luo, L; Wei, Q; Zhang, C; Zhao, J | 1 |
| Brooks, SV; Miller, RA; Zaseck, LW | 1 |
| Chen, H; Dai, J; He, J; Li, X; Sun, Y; Wang, D; Wang, J; Yan, L; Zhao, S | 1 |
| Chung, EJ; Chung, SI; Citrin, DE; McKay-Corkum, G; Mitchell, JB; Sowers, A; Thetford, A | 1 |
12 other study(ies) available for hydroxyproline and sirolimus
| Article | Year |
|---|---|
Mutational biosynthesis of novel rapamycins by a strain of Streptomyces hygroscopicus NRRL 5491 disrupted in rapL, encoding a putative lysine cyclodeaminase.
Topics: Ammonia-Lyases; Cell Cycle; Frameshift Mutation; Gas Chromatography-Mass Spectrometry; Genes, Bacterial; Hydroxyproline; Immunosuppressive Agents; Magnetic Resonance Spectroscopy; Multigene Family; Pipecolic Acids; Polyenes; Sirolimus; Streptomyces | 1998 |
The rapamycin analogue SDZ RAD attenuates bleomycin-induced pulmonary fibrosis in rats.
Topics: Animals; Antimetabolites, Antineoplastic; Bleomycin; Collagen; Everolimus; Hydroxyproline; Immunosuppressive Agents; Lung; Male; Organ Size; Pulmonary Fibrosis; Rats; Rats, Inbred Lew; Sirolimus; Spleen | 2002 |
Sirolimus impairs wound healing.
Topics: Animals; Cell Proliferation; Collagen; Dose-Response Relationship, Drug; Hydroxyproline; Immunosuppressive Agents; Lymphocytes; Models, Animal; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Sirolimus; Skin; Vascular Endothelial Growth Factor A; Wound Healing | 2007 |
Everolimus interferes with the inflammatory phase of healing in experimental colonic anastomoses.
Topics: Anastomosis, Surgical; Animals; Colon; Everolimus; Hydroxyproline; Immunosuppressive Agents; Inflammation; Interleukin-6; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Models, Animal; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Sirolimus; TOR Serine-Threonine Kinases; Wound Healing | 2011 |
Prolidase-dependent regulation of TGF β (corrected) and TGF β receptor expressions in human skin fibroblasts.
Topics: Cells, Cultured; Dipeptidases; Down-Regulation; Fibroblasts; Humans; Hydroxyproline; Osmolar Concentration; Phosphoenolpyruvate; Phosphorylation; Proline; Protease Inhibitors; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Sirolimus; Skin; TOR Serine-Threonine Kinases; Transforming Growth Factor beta1; Up-Regulation | 2010 |
Rapamycin-induced impaired wound healing is associated with compromised tissue lactate accumulation and extracellular matrix remodeling.
Topics: Animals; Extracellular Matrix; Hydroxyproline; Immunosuppressive Agents; Lactic Acid; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Sirolimus; Tensile Strength; Tissue Distribution; Wound Healing | 2011 |
Everolimus-induced loss of wound strength can be prevented by a short postoperative delay in its administration.
Topics: Administration, Oral; Anastomosis, Surgical; Animals; Collagen; Colon; Drug Administration Schedule; Everolimus; Hydroxyproline; Ileum; Immunosuppressive Agents; In Vitro Techniques; Laparotomy; Male; Postoperative Period; Rats; Rats, Wistar; Sirolimus; Tensile Strength; TOR Serine-Threonine Kinases; Wound Healing | 2011 |
Lack of efficacy of mTOR inhibitors and ACE pathway inhibitors as antifibrotic agents in evolving and established fibrosis in Mdr2⁻/⁻ mice.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Biphenyl Compounds; Captopril; Drug Therapy, Combination; Everolimus; Female; Gene Expression Regulation; Hydroxyproline; Irbesartan; Liver; Liver Cirrhosis, Experimental; Male; Mice, Knockout; Protein Kinase Inhibitors; Renin-Angiotensin System; Signal Transduction; Sirolimus; Species Specificity; Tetrazoles; Time Factors; TOR Serine-Threonine Kinases | 2015 |
Effects of rapamycin on reduction of peridural fibrosis: an experimental study.
Topics: Analysis of Variance; Animals; Cell Proliferation; Cells, Cultured; Cytokines; DNA Primers; Drug Evaluation, Preclinical; Fibroblasts; Fibrosis; Hydroxyproline; Laminectomy; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Sirolimus; Spinal Cord; Vimentin | 2015 |
Rapamycin Attenuates Age-associated Changes in Tibialis Anterior Tendon Viscoelastic Properties.
Topics: Aging; Animals; Biomechanical Phenomena; Collagen; Elasticity; Extracellular Matrix; Female; Hydroxyproline; Immunosuppressive Agents; Long Term Adverse Effects; Matrix Metalloproteinase 8; Mice; Muscle, Skeletal; Sirolimus; Tendons | 2016 |
Local application of rapamycin reduces epidural fibrosis after laminectomy via inhibiting fibroblast proliferation and prompting apoptosis.
Topics: Animals; Apoptosis; Cell Proliferation; Cells, Cultured; Cicatrix; Epidural Space; Fibroblasts; Fibrosis; Hydroxyproline; Immunosuppressive Agents; In Situ Nick-End Labeling; Laminectomy; Male; Random Allocation; Rats, Sprague-Dawley; Sirolimus | 2016 |
Mammalian Target of Rapamycin Inhibition With Rapamycin Mitigates Radiation-Induced Pulmonary Fibrosis in a Murine Model.
Topics: Alveolar Epithelial Cells; Animals; beta-Galactosidase; Cellular Senescence; Extracellular Matrix; Female; Hydroxyproline; Interleukin-1beta; Lung; Macrophages; Mice; Mice, Inbred C57BL; Radiation Pneumonitis; Radiation Tolerance; Radiation-Protective Agents; Sirolimus; TOR Serine-Threonine Kinases; Transforming Growth Factor beta | 2016 |