Page last updated: 2024-08-17

hydroxyproline and pyridinoline

hydroxyproline has been researched along with pyridinoline in 115 studies

Research

Studies (115)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (2.61)	18.7374
1990's	79 (68.70)	18.2507
2000's	28 (24.35)	29.6817
2010's	4 (3.48)	24.3611
2020's	1 (0.87)	2.80

Authors

Authors	Studies
Baylink, DJ; Bettica, P; Moro, L; Robins, SP; Singer, FR; Talbot, J; Taylor, AK	1
Duncan, A; Kovanen, V; Palokangas, H; Robins, SP	1
Bollen, AM; Eyre, DR; Hanson, DA; Maslan, SL; Singer, FR; Weis, MA	1
Horiuchi, K; Inoue, T; Ishigaki, S; Kushida, K; Ohishi, T; Takahashi, M	1
Christiansen, C; Delmas, PD; Gineyts, E; Riis, B; Schlemmer, A	1
Black, D; Duncan, A; Paterson, CR; Reid, DM; Robins, SP; Seibel, MJ	1
Haque, Z; Prisayanh, P; Woodley, DT; Yamauchi, M	1
Adachi, JD	1
Christiansen, C; Delmas, PD; Gineyts, E; Johansen, JS; Schlemmer, A; Uebelhart, D	1
Brown, PJ; David, JS; Etherington, DJ; Kaidi, R; Robins, SP	1
Monnier, VM; Sell, DR	1
Kyogoku, H	1
Anderson, JC; Hasleton, PS; Robins, SP; Whittle, MA	1
Chowdhury, H; Robins, SP; Schwartz, EI; Shapses, SA	1
Besterman, JM; McSherry, SA; Miyamoto, KK; Mohler, JL; Robins, SP	1
Chaki, O; Gorai, I; Minaguchi, H; Nakayama, M	1
Assiri, AM; Blumsohn, A; Eastell, R; Naylor, KE	1
Claassen, N; Coetzer, H; Kruger, MC; Potgieter, HC; Seppa, M; Van Papendorp, DH; Vermaak, WJ	1
Brazier, M; Castelain, S; Desmet, G; Kamel, S; Picard, C; Sebert, JL	1
Arlot, ME; Delmas, PD; Meunier, PJ; Nilssen, MH; Pastoureau, P; Vergnaud, P	1
Alfano, FS; Basini, G; Campanini, C; Fantuzzi, M; Gatti, C; Girasole, G; Passeri, M; Pedrazzoni, M	1
Akesson, K	1
Jensen, JE; Jensen, LB; Kollerup, G; Sørensen, HA; Sørensen, OH	1
Eyre, D; Frank, C; McDonald, D; Shrive, N; Wilson, J	1
Kruse, K; Rauch, F; Schönau, E; Seibel, M; Woitge, H	1
Alvarez, L; Ballesta, AM; Bedini, JL; Deulofeu, R; Guañabens, N; Martinez de Osaba, MJ; Monegal, A; Muñoz-Gomez, J; Peris, P; Rivera-Fillat, F	1
Chen, JT; Hasumi, K; Hirai, Y; Katase, K; Kato, T; Shiraki, M; Shiraki, Y	1
Gosselin, LE; Martinez, DA; Sieck, GC; Vailas, AC	1
Baylink, DJ; Libanati, C; Lueken, SA; Taylor, AK	1
Goh, D; Horowitz, M; Morris, HA; Need, AG; Nordin, BE; Wishart, JM	1
Burleson, JA; Deftos, LJ; Delmas, PD; Pilbeam, CC; Prestwood, KM; Raisz, LG; Woodiel, FN	1
Rauch, F; Remer, T; Schönau, E; Seibel, M; Woitge, H	1
Clemens, JD; Dresner-Pollak, R; Greenspan, SL; Moses, AC; Rosen, HN; Rosenblatt, M; Zeind, AJ	1
Birkenhäger, JC; Pols, HA; van Daele, PL	1
Colwell, A; Eastell, R; Hamdy, NA; Papapoulos, SE; Russell, RG	1
Delmas, PD	2
Christiansen, C; Hassager, C; Jensen, SB; Risteli, J; Risteli, L; Schlemmer, A	1
Arnaud, SB; Baylink, DJ; Lueken, SA; Taylor, AK	1
Katayama, Y; Kugai, N; Nagata, N; Wada, S; Yasutomo, Y	1
Cosman, F; Dempster, DW; Gordon, S; Lindsay, R; Ratcliffe, A; Seibel, MJ; Shen, V	1
Rivera, EM; Yamauchi, M	1
Chen, T; Greenspan, SL; Gundberg, C; Holick, M; Kung, VT; Moses, AC; Rosen, HN; Seyedin, SM	1
Assiri, AM; Colwell, T; Eastell, R; Riggs, BL; Robins, SP; Russell, RG	1
Daniloff, YN; Gomez, B; Hesley, RP; Kung, VT; Nielsen, LA; Rosen, HN; Seyedin, SM; Zuk, RF	1
Bijlsma, JW; Gerrits, MI; Jacobs, JW; Lems, WF; van Rijn, HJ; van Vugt, RM	1
Açil, Y; Bätge, B; Brinckmann, J; Koch, MH; Müller, PK; Notbohm, H; Schmeller, W; Tronnier, M; Wolff, HH	1
Inoue, T; Kawana, K; Kushida, K; Ohishi, T; Takahashi, M; Yagi, K	1
de la Piedra, C; Diaz Diego, EM; Diaz Martin, MA; Disla, T; Guerrero, R; Rapado, A	1
Coleman, RE; Eastell, R; Guo, CY; Purohit, OP; Vinholes, J	1
Body, JJ; Delmas, PD; Dumon, JC; Gineyts, E	1
Cepollaro, C; Gennari, C; Gennari, L; Gonnelli, S; Montagnani, A; Montomoli, M; Palmieri, R	1
Divieti, P; Polo, RM; Resmini, G; Rubinacci, A; Tenni, R; Zampino, M	1
Brüel, A; Oxlund, H	1
Russell, RG	1
Cruz, C; Jiménez, F; Pedraza-Chaverrí, J; Sierra, RI; Specker, BL	1
Charles, P; Eriksen, EF; Langdahl, BL; Loft, AG; Mosekilde, L; Møller, N; Weeke, J	1
Beck-Jensen, JE; Kollerup, G; Pors Nielsen, S; Sørensen, HA; Sørensen, OH	1
Hyldstrup, L; Kollerup, G; Storm, T; Sørensen, HA	1
Horowitz, M; Morris, HA; Need, AG; Nordin, BE; Scopacasa, F; Wishart, JM; Wittert, G	1
Amama, EA; Minaguchi, H; Taga, M	1
Hosoi, T; Ikegami, A; Kasugai, Y; Matsuo, K; Ohashi, M; Orimo, H; Ouchi, Y; Sukamoto, T	1
Farquharson, R; Fraser, WD; Hipkin, L; Lesse, GP; Vora, JP	1
Arokosi, J; Jaroma, H; Kiviranta, I; Kovanen, V; Tammi, M; Väätäinen, U	1
Bernardi, D; Bonato, P; Plebani, M; Ujka, F; Zaninotto, M	1
Katz, EP; Marshall, MK; Tanzawa, H; Uzawa, K; Yamauchi, M; Yeowell, HN	1
Hoshino, H; Inoue, T; Kitazawa, A; Kushida, K; Ohishi, T; Takahashi, M; Yamazaki, K	1
Akiyama, T; Fukuda, C; Iijima, Y; Kiyokawa, A; Matsushita, Y; Miyamoto, M; Sugano, M	1
Eicher, R; Kraenzlin, M; Liesegang, A; Riond, JL; Rüsch, P; Wanner, M	1
Chan, BP; Chan, KM; Fu, SC; Qin, L; Rolf, C	1
Gerrits, MI; Oldenhave, A; Thijssen, JH; Vecht-Hart, IM	1
Heine, H; Müller, A; Sprott, H	1
Hein, G; Lehmann, G; Müller, A; Stein, G	1
Hirsimäki, Y; Kangas, L; Karlsson, S; Mäntylä, E; Niemi, S; Nieminen, K; Nieminen, L	1
Kosaka, N; Sugiyama, T; Takashima, M; Uchii, M	1
Titus, K	1
Bandiera, P; Montella, A; Ostrowski, K; Sotowski, R; Wojtowicz, A; Yamauchi, M	1
Arokoski, JP; Haapala, J; Helminen, HJ; Hyttinen, MM; Kiviranta, I; Kovanen, V; Lammi, M; Tammi, M	1
Miller, GR; Smith, CA; Stauber, WT	1
Bruni, D; Cepollaro, C; Gennari, C; Gonnelli, S; Martini, S; Montagnani, A; Pondrelli, C	1
Kraenzlin, M; Liesegang, A; Reutter, R; Riond, JL; Risteli, J; Sassi, ML; Wanner, M	1
Alvarez, L; Ballesta, AM; Durán, M; Echevarría, M; Guañabens, N; Martínez de Osaba, MJ; Monegal, A; Muñoz-Gómez, J; Peris, P; Pons, F	1
Bank, RA; Barneveld, A; Brama, PA; Tekoppele, JM; van Weeren, PR	1
Açil, Y; Dunsche, A; Fleiner, B; Jepsen, S; Terheyden, H	1
Kääpä, E; Konttinen, YT; Lammi, MJ; Poussa, M; Takala, TE; Vanharanta, H; Wang, W	1
Horowitz, M; Morris, HA; Need, AG; Nordin, BE; Scopacasa, F; Wishart, JM	1
Schmolke, B	1
Bigbee, AJ; Buckendahl, PE; Dotsenko, MA; Grindeland, RE; Martinez, DA; Vailas, AC	1
Arnaud, SB; Bromage, T; Buckendahl, P; Durnova, G; Yamauchi, M	1
Komukai, S; Makita, K; Nozawa, S; Ohta, H	1
Guhl, DJ; Martinez, DA; Stanley, WC; Vailas, AC	1
Margulies, KB; McCormick, RJ; McGowan, BS; Mu, A; Scott, CB; Thomas, DP	1
Cole, R; D'Armiento, J; Foronjy, RF; Okada, Y	1
Challa, A; Lapatsanis, PD; Papadopoulou, ZL; Siamopoulou, A; Siomou, E; Tzoufi, M	1
Hsu, RW; Hsu, WH; Lee, KF; Tai, CL	1
Baldellou Vázquez, A; Fernández-Espuelas, C; González López, JM; Manjón Llorente, G; Ruiz-Echarri, MP	1
Corradetti, A; Giannubilo, SR; Tranquilli, AL	1
Evans, GS; Lin, YS; Powers, HJ; Stuart, EL	1
Lello, S; Melis, GB; Migliaccio, S; Paoletti, AM	1
Açil, Y; Mobasseri, AE; Springer, I; Terheyden, H; Warnke, PH; Wiltfang, J	1
Choy, VE; Crenshaw, TD; Kyparos, A; Martinez, DA; Vailas, AC	1
Osada, H; Sakamoto, R; Seki, K; Sekiya, S	1
Abe, M; Nagano, A; Takahashi, M	1
Camozzi, V; Francucci, CM; Moro, L; Pagani, F; Simoni, E; Tossi, A	1
Abe, M; Nagano, A; Suzuki, D; Takahashi, M	1
Hasegawa, K; Inoue, M; Kataoka, K; Morishima, T; Seino, Y; Tanaka, H	1
Fuller, CA; Hoban-Higgins, TM; Lust, A; Martinez, DA; Patterson-Buckendahl, PE; Shea-Rangel, KM; Vailas, AC	1
Lee, JD; Lemoine, JK; Trappe, TA	1
Dong, W; Gao, B; Li, D; Liu, H; Yang, J; Zhang, Y	1
Aagaard, P; Couppé, C; Hansen, P; Kjaer, M; Kongsgaard, M; Kovanen, V; Magnusson, SP; Suetta, C	1
Bank, RA; Doulabi, BZ; Everts, V; Helder, MN; Hoogendoorn, RJ; Huang, C; Kroeze, RJ; Vonk, LA	1
Sroga, GE; Vashishth, D	1
Açil, Y; Behrens, C; Gassling, V; Gierloff, M; Möller, B; Niehoff, P; Simon, M; Wiltfang, J	1
Arthur, KA; Broderick, TL; Carroll, CC; Huynh, RT; Martineau, K; Volper, BD	1
Chen, XY; Feng, FC; He, HL; Li, RF; Xu, Y; Zhou, XM	1

Reviews

7 review(s) available for hydroxyproline and pyridinoline

Article	Year
Biochemical markers of bone turnover. A review. Acta orthopaedica Scandinavica, 1995, Volume: 66, Issue:4 Topics: Adult; Aged; Aging; Alkaline Phosphatase; Amino Acids; Biomarkers; Bone Diseases; Bone Remodeling; Child; Collagen; Extracellular Matrix Proteins; Female; Fractures, Bone; Humans; Hydroxyproline; Middle Aged; Osteocalcin; Peptide Fragments; Procollagen	1995
Biochemical markers of bone turnover: an update. The Netherlands journal of medicine, 1994, Volume: 44, Issue:2 Topics: Acid Phosphatase; Alkaline Phosphatase; Amino Acids; Biomarkers; Bone and Bones; Bone Remodeling; Bone Resorption; Humans; Hydroxyproline; Osteocalcin; Peptide Fragments; Procollagen; Reproducibility of Results	1994
Biochemical markers of bone turnover. I: Theoretical considerations and clinical use in osteoporosis. The American journal of medicine, 1993, Nov-30, Volume: 95, Issue:5A Topics: Alkaline Phosphatase; Amino Acids; Biomarkers; Bone Density; Bone Resorption; Calcium; Female; Hip Fractures; Humans; Hydroxyproline; Osteocalcin; Osteogenesis; Osteoporosis; Peptide Fragments; Procollagen	1993
[Biological markers of bone metabolism]. Presse medicale (Paris, France : 1983), 1993, Feb-20, Volume: 22, Issue:6 Topics: Acid Phosphatase; Alkaline Phosphatase; Amino Acids; Biomarkers; Bone and Bones; Calcium; Female; Humans; Hydroxyproline; Male; Osteocalcin; Osteoporosis; Osteoporosis, Postmenopausal; Peptides; Procollagen	1993
The assessment of bone metabolism in vivo using biochemical approaches. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1997, Volume: 29, Issue:3 Topics: Amino Acids; Biomarkers; Bone and Bones; Bone Remodeling; Humans; Hydroxyproline; Osteocalcin; Procollagen	1997
Bone markers: biochemical and clinical significance. Aging clinical and experimental research, 2004, Volume: 16 Suppl, Issue:3 Topics: Alkaline Phosphatase; Amino Acids; Biomarkers; Bone and Bones; Bone Remodeling; Bone Resorption; Humans; Hydroxyproline; Osteocalcin; Osteogenesis; Osteoporosis; Peptide Fragments; Procollagen	2004
Role of biochemical markers of bone remodeling in clinical practice. Journal of endocrinological investigation, 2007, Volume: 30, Issue:6 Suppl Topics: Acid Phosphatase; Alkaline Phosphatase; Amino Acids; Biomarkers; Bone Remodeling; Collagen Type I; Humans; Hydroxyproline; Isoenzymes; Osteocalcin; Peptides; Practice Patterns, Physicians'; Tartrate-Resistant Acid Phosphatase	2007

Trials

9 trial(s) available for hydroxyproline and pyridinoline

Article	Year
Short-term changes in calcium but not protein intake alter the rate of bone resorption in healthy subjects as assessed by urinary pyridinium cross-link excretion. The Journal of nutrition, 1995, Volume: 125, Issue:11 Topics: Adult; Amino Acids; Bone Resorption; Calcium; Calcium, Dietary; Collagen; Creatinine; Dietary Proteins; Female; Humans; Hydroxyproline; Male; Nitrogen; Time Factors	1995
Discriminative value of biochemical markers of bone turnover in assessing the activity of Paget's disease. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1995, Volume: 10, Issue:3 Topics: Acid Phosphatase; Adult; Aged; Aged, 80 and over; Alkaline Phosphatase; Amino Acids; Biomarkers; Bone Development; Bone Resorption; Collagen; Collagen Type I; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hydroxyproline; Male; Middle Aged; Osteitis Deformans; Peptide Fragments; Peptides; Procollagen	1995
Specificity of urinary excretion of cross-linked N-telopeptides of type I collagen as a marker of bone turnover. Calcified tissue international, 1994, Volume: 54, Issue:1 Topics: Adolescent; Adult; Amino Acids; Analysis of Variance; Biomarkers; Bone Resorption; Calcium; Collagen; Collagen Type I; Creatinine; Diphosphonates; Humans; Hydroxyproline; Male; Pamidronate; Peptides; Thyrotropin; Triiodothyronine	1994
Therapy with parenteral pamidronate prevents thyroid hormone-induced bone turnover in humans. The Journal of clinical endocrinology and metabolism, 1993, Volume: 77, Issue:3 Topics: Adolescent; Adult; Amino Acids; Bone Resorption; Calcitriol; Calcium; Creatinine; Diphosphonates; Humans; Hydroxyproline; Infusions, Intravenous; Male; Osteocalcin; Pamidronate; Parathyroid Hormone; Triiodothyronine	1993
Evaluation of new bone resorption markers in a randomized comparison of pamidronate or clodronate for hypercalcemia of malignancy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Amino Acids; Biomarkers; Bone Neoplasms; Bone Resorption; Calcium; Clodronic Acid; Collagen; Collagen Type I; Diphosphonates; Double-Blind Method; Female; Humans; Hydroxyproline; Hypercalcemia; Male; Middle Aged; Pamidronate; Parathyroid Hormone; Peptides	1997
Treatment of post-menopausal osteoporosis with recombinant human growth hormone and salmon calcitonin: a placebo controlled study. Clinical endocrinology, 1997, Volume: 46, Issue:1 Topics: Amino Acids; Analgesics; Bone Density; Calcitonin; Calcium; Drug Therapy, Combination; Female; Femur; Human Growth Hormone; Humans; Hydroxyproline; Lumbar Vertebrae; Middle Aged; Osteocalcin; Osteoporosis, Postmenopausal; Placebos; Radius	1997
Assessment of different markers of bone resorption in postmenopausal osteoporotic women treated with pamidronate. Scandinavian journal of clinical and laboratory investigation, 1997, Volume: 57, Issue:6 Topics: Aged; Amino Acids; Biomarkers; Bone Resorption; Chromatography, High Pressure Liquid; Diphosphonates; Double-Blind Method; Female; Humans; Hydroxyproline; Kinetics; Middle Aged; Osteoporosis, Postmenopausal; Pamidronate; Placebos	1997
Calcium supplementation suppresses bone resorption in early postmenopausal women. Calcified tissue international, 1998, Volume: 62, Issue:1 Topics: Amino Acids; Biomarkers; Bone Resorption; Calcium; Creatinine; Dietary Supplements; Drug Administration Schedule; Female; Humans; Hydroxyproline; Middle Aged; Parathyroid Hormone; Phosphates; Postmenopause; Time Factors; Urination	1998
Inhibition of bone resorption by divided-dose calcium supplementation in early postmenopausal women. Calcified tissue international, 2000, Volume: 67, Issue:6 Topics: Amino Acids; Biomarkers; Bone Resorption; Calcium; Dietary Supplements; Drug Administration Schedule; Female; Humans; Hydroxyproline; Middle Aged; Osteoporosis, Postmenopausal; Time Factors	2000

Other Studies

99 other study(ies) available for hydroxyproline and pyridinoline

Article	Year
Bone-resorption markers galactosyl hydroxylysine, pyridinium crosslinks, and hydroxyproline compared. Clinical chemistry, 1992, Volume: 38, Issue:11 Topics: Adult; Aged; Amino Acids; Biomarkers; Bone Resorption; Child; Chromatography, High Pressure Liquid; Female; Humans; Hydroxylysine; Hydroxyproline; Male; Middle Aged; Osteitis Deformans; Osteoporosis, Postmenopausal; Pyridinium Compounds	1992
Age-related changes in the concentration of hydroxypyridinium crosslinks in functionally different skeletal muscles. Matrix (Stuttgart, Germany), 1992, Volume: 12, Issue:4 Topics: Aging; Amino Acids; Animals; Chromatography, High Pressure Liquid; Hydroxyproline; Male; Muscles; Rats; Tendons	1992
A specific immunoassay for monitoring human bone resorption: quantitation of type I collagen cross-linked N-telopeptides in urine. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1992, Volume: 7, Issue:11 Topics: Adolescent; Adult; Aged; Amino Acid Sequence; Amino Acids; Antibodies, Monoclonal; Bone Diseases, Metabolic; Bone Resorption; Child; Child, Preschool; Collagen; Creatinine; Enzyme-Linked Immunosorbent Assay; Humans; Hydroxyproline; Infant; Male; Middle Aged; Molecular Sequence Data; Molecular Weight; Osteitis Deformans; Peptides	1992
Quantitative analyses of urinary pyridinoline and deoxypyridinoline excretion in patients with hyperthyroidism. Endocrine research, 1992, Volume: 18, Issue:4 Topics: Adult; Alkaline Phosphatase; Amino Acids; Biomarkers; Bone Resorption; Female; Humans; Hydroxyproline; Hyperthyroidism; Middle Aged; Thyroxine; Triiodothyronine	1992
Urinary excretion of pyridinoline crosslinks correlates with bone turnover measured on iliac crest biopsy in patients with vertebral osteoporosis. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1991, Volume: 6, Issue:6 Topics: Aged; Amino Acids; Biomarkers; Bone and Bones; Bone Regeneration; Bone Resorption; Female; Humans; Hydroxyproline; Kinetics; Middle Aged; Osteocalcin; Osteoclasts; Osteoporosis, Postmenopausal	1991
Evaluation of urinary hydroxypyridinium crosslink measurements as resorption markers in metabolic bone diseases. European journal of clinical investigation, 1991, Volume: 21, Issue:3 Topics: Aged; Aged, 80 and over; Amino Acids; Biomarkers; Bone Diseases, Metabolic; Bone Resorption; Collagen; Humans; Hydroxyproline; Hyperparathyroidism; Middle Aged; Osteitis Deformans; Osteomalacia	1991
Collagen cross-linking in sun-exposed and unexposed sites of aged human skin. The Journal of investigative dermatology, 1991, Volume: 97, Issue:5 Topics: Adult; Aged; Amino Acids; Collagen; Cross-Linking Reagents; Humans; Hydroxyproline; Oligopeptides; Skin; Ultraviolet Rays	1991
Markers of bone turnover in rheumatoid arthritis. The Journal of rheumatology, 1991, Volume: 18, Issue:8 Topics: Acid Phosphatase; Amino Acids; Arthritis, Rheumatoid; Biomarkers; Bone and Bones; Humans; Hydroxyproline	1991
Effect of menopause and hormone replacement therapy on the urinary excretion of pyridinium cross-links. The Journal of clinical endocrinology and metabolism, 1991, Volume: 72, Issue:2 Topics: Amino Acids; Chromatography, High Pressure Liquid; Collagen; Female; Humans; Hydroxyproline; Middle Aged; Osteocalcin; Osteoporosis, Postmenopausal	1991
Uterine collagen during involution in cattle. Matrix (Stuttgart, Germany), 1991, Volume: 11, Issue:2 Topics: Amino Acids; Animals; Cattle; Collagen; Female; Hydroxyproline; Microscopy, Electron; Postpartum Period; Pregnancy; Uterus	1991
Isolation, purification and partial characterization of novel fluorophores from aging human insoluble collagen-rich tissue. Connective tissue research, 1989, Volume: 19, Issue:1 Topics: Aging; Amino Acids; Chromatography, Gel; Chromatography, High Pressure Liquid; Chromatography, Paper; Collagen; Connective Tissue; Diabetes Mellitus; Dura Mater; Fluorescent Dyes; Humans; Hydroxyproline; Molecular Weight; Solubility; Spectrometry, Fluorescence; Spectrophotometry; Trypsin	1989
[Biochemical study on interstitial proteins of human gastric cancer tissue with special reference to cross-linking amino acids of collagen and elastin]. [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1988, Volume: 63, Issue:6 Topics: Amino Acids; Collagen; Dipeptides; Elastin; Humans; Hydroxyproline; Stomach Neoplasms	1988
Biochemical investigation of possible lesions in human aorta that predispose to dissecting aneurysms: pyridinoline crosslinks. Cardiovascular research, 1987, Volume: 21, Issue:3 Topics: Aged; Aged, 80 and over; Amino Acids; Aorta; Aorta, Thoracic; Aortic Aneurysm; Aortic Dissection; Female; Humans; Hydroxyproline; Male; Middle Aged	1987
Collagen cross-link metabolites in urine as markers of bone metastases in prostatic carcinoma. The Journal of urology, 1994, Volume: 151, Issue:4 Topics: Aged; Amino Acids; Biomarkers, Tumor; Bone Neoplasms; Circadian Rhythm; Collagen; Creatinine; Humans; Hydroxyproline; Male; Middle Aged; Prostatic Hyperplasia; Prostatic Neoplasms	1994
Urinary biochemical markers for bone resorption during the menstrual cycle. Calcified tissue international, 1995, Volume: 57, Issue:2 Topics: Adult; Amino Acids; Biomarkers; Bone Resorption; Female; Follicular Phase; Humans; Hydroxyproline; Luteal Phase; Luteinizing Hormone; Menstrual Cycle; Middle Aged; Reference Values	1995
Different responses of biochemical markers of bone resorption to bisphosphonate therapy in Paget disease. Clinical chemistry, 1995, Volume: 41, Issue:11 Topics: Acid Phosphatase; Aged; Aged, 80 and over; Amino Acids; Biomarkers; Bone Resorption; Chromatography, High Pressure Liquid; Collagen; Drug Resistance; Etidronic Acid; Female; Humans; Hydroxyproline; Male; Middle Aged; Osteitis Deformans; Peptide Fragments; Tartrates; Testosterone	1995
Supplemented gamma-linolenic acid and eicosapentaenoic acid influence bone status in young male rats: effects on free urinary collagen crosslinks, total urinary hydroxyproline, and bone calcium content. Bone, 1995, Volume: 16, Issue:4 Suppl Topics: Amino Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Resorption; Calcium; Eating; Eicosapentaenoic Acid; Fatty Acids; Fatty Acids, Essential; Femur; Fish Oils; gamma-Linolenic Acid; Hydroxyproline; Linoleic Acids; Lipids; Male; Oenothera biennis; Organ Size; Plant Oils; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence	1995
A simple and automated HPLC method for determination of total hydroxyproline in urine. Comparison with excretion of pyridinolines. Clinica chimica acta; international journal of clinical chemistry, 1995, Feb-28, Volume: 235, Issue:1 Topics: Aged; Amino Acids; Bone Resorption; Chromatography, High Pressure Liquid; Colorimetry; Female; Fluorenes; Humans; Hydroxyproline; Middle Aged; Postmenopause; Regression Analysis; Reproducibility of Results	1995
The anabolic effect of human PTH (1-34) on bone formation is blunted when bone resorption is inhibited by the bisphosphonate tiludronate--is activated resorption a prerequisite for the in vivo effect of PTH on formation in a remodeling system? Bone, 1995, Volume: 16, Issue:6 Topics: Alkaline Phosphatase; Amino Acids; Analysis of Variance; Animals; Biomechanical Phenomena; Bone Density; Bone Development; Bone Resorption; Diphosphonates; Disease Models, Animal; Female; Humans; Hydroxyproline; Ilium; Injections, Subcutaneous; Osteocalcin; Osteoclasts; Osteoporosis, Postmenopausal; Parathyroid Hormone; Peptide Fragments; Sheep; Teriparatide	1995
Acute effects of bisphosphonates on new and traditional markers of bone resorption. Calcified tissue international, 1995, Volume: 57, Issue:1 Topics: Acid Phosphatase; Aged; Aged, 80 and over; Alendronate; Amino Acids; Biomarkers; Bone and Bones; Bone Resorption; Clodronic Acid; Collagen; Collagen Type I; Diphosphonates; Female; Humans; Hydroxyproline; Injections, Intravenous; Male; Middle Aged; Osteitis Deformans; Osteoporosis; Peptides; Time Factors	1995
Biological variation of biochemical bone markers. Scandinavian journal of clinical and laboratory investigation. Supplementum, 1994, Volume: 219 Topics: Alkaline Phosphatase; Amino Acids; Biomarkers; Bone and Bones; Calcium; Creatinine; Female; Genetic Variation; Humans; Hydroxyproline; Middle Aged; Osteocalcin; Osteoporosis, Postmenopausal	1994
Rabbit medial collateral ligament scar weakness is associated with decreased collagen pyridinoline crosslink density. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 1995, Volume: 13, Issue:2 Topics: Amino Acids; Animals; Cicatrix; Collagen; Female; Hydroxyproline; Linear Models; Medial Collateral Ligament, Knee; Rabbits; Tensile Strength; Wound Healing	1995
Increased urinary excretion of collagen crosslinks in girls with Ullrich-Turner syndrome. Acta paediatrica (Oslo, Norway : 1992), 1995, Volume: 84, Issue:1 Topics: Adolescent; Amino Acids; Bone Resorption; Child; Child, Preschool; Collagen; Female; Humans; Hydroxyproline; Turner Syndrome	1995
[Time course changes in bone metabolic markers after menopause--a cross-sectional study]. Nihon Sanka Fujinka Gakkai zasshi, 1995, Volume: 47, Issue:1 Topics: Adult; Alkaline Phosphatase; Amino Acids; Biomarkers; Bone and Bones; Bone Density; Creatinine; Cross-Sectional Studies; Female; Humans; Hydroxyproline; Matched-Pair Analysis; Middle Aged; Osteocalcin; Postmenopause	1995
Passive length-force properties of senescent diaphragm: relationship with collagen characteristics. Journal of applied physiology (Bethesda, Md. : 1985), 1994, Volume: 76, Issue:6 Topics: Aging; Amino Acids; Animals; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Diaphragm; Electric Stimulation; Hydroxyproline; In Vitro Techniques; Male; Muscle Contraction; Muscle Development; Rats; Rats, Inbred F344	1994
Biochemical markers of bone turnover for the clinical assessment of bone metabolism. Rheumatic diseases clinics of North America, 1994, Volume: 20, Issue:3 Topics: Acid Phosphatase; Alkaline Phosphatase; Amino Acids; Biomarkers; Bone Development; Bone Resorption; Humans; Hydroxylysine; Hydroxyproline; Osteocalcin; Procollagen; Reproducibility of Results	1994
Oral calcium suppresses biochemical markers of bone resorption in normal men. The American journal of clinical nutrition, 1994, Volume: 60, Issue:6 Topics: Absorption; Adult; Amino Acids; Biomarkers; Bone Resorption; Calcium; Calcium Radioisotopes; Creatinine; Humans; Hydroxyproline; Male; Middle Aged; Parathyroid Hormone	1994
The short-term effects of conjugated estrogen on bone turnover in older women. The Journal of clinical endocrinology and metabolism, 1994, Volume: 79, Issue:2 Topics: Aged; Aged, 80 and over; Alkaline Phosphatase; Amino Acids; Bone and Bones; Bone Density; Bone Resorption; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Humans; Hydroxyproline; Osteocalcin; Peptide Fragments; Postmenopause; Procollagen	1994
Urinary excretion of hydroxy-pyridinium cross-links of collagen reflects skeletal growth velocity in normal children. Experimental and clinical endocrinology, 1994, Volume: 102, Issue:2 Topics: Adolescent; Adult; Aging; Amino Acids; Bone Development; Child; Child, Preschool; Creatinine; Female; Humans; Hydroxyproline; Male; Reference Values; Regression Analysis	1994
Urinary collagen crosslink excretion: a better index of bone resorption than hydroxyproline in Paget's disease of bone? Bone and mineral, 1993, Volume: 22, Issue:1 Topics: Amino Acids; Biomarkers; Bone Resorption; Calcitonin; Chromatography, High Pressure Liquid; Diphosphonates; Fluorometry; Humans; Hydroxyproline; Injections, Intravenous; Osteitis Deformans; Pamidronate	1993
Possible variation in bone resorption during the normal menstrual cycle. Acta endocrinologica, 1993, Volume: 129, Issue:5 Topics: Adult; Alkaline Phosphatase; Amino Acids; Bone Resorption; Collagen; Collagen Type I; Creatine; Estradiol; Female; Humans; Hydroxyproline; Menstrual Cycle; Osteocalcin; Peptide Fragments; Peptides; Premenopause; Procollagen	1993
Changes in markers of bone formation and resorption in a bed rest model of weightlessness. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1993, Volume: 8, Issue:12 Topics: Acid Phosphatase; Adult; Alkaline Phosphatase; Amino Acids; Bed Rest; Biomarkers; Bone and Bones; Bone Development; Bone Resorption; Creatinine; Humans; Hydroxyproline; Male; Osteocalcin; Weightlessness	1993
Changes of bone metabolic markers in patients with bone metastases: clinical significance in assessing bone response to chemotherapy. Internal medicine (Tokyo, Japan), 1993, Volume: 32, Issue:8 Topics: Adult; Aged; Alkaline Phosphatase; Amino Acids; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone and Bones; Bone Neoplasms; Bone Resorption; Female; Humans; Hydroxyproline; Male; Middle Aged; Osteocalcin; Osteogenesis; Prognosis	1993
Urinary hydroxypyridinium crosslinks of collagen as markers of bone resorption and estrogen efficacy in postmenopausal osteoporosis. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1993, Volume: 8, Issue:7 Topics: Acid Phosphatase; Adult; Aged; Amino Acids; Biomarkers; Bone Density; Bone Resorption; Collagen; Cross-Sectional Studies; Estrogen Replacement Therapy; Female; Humans; Hydroxyproline; Menopause; Middle Aged; Osteoporosis, Postmenopausal	1993
Site comparisons of dentine collagen cross-links from extracted human teeth. Archives of oral biology, 1993, Volume: 38, Issue:7 Topics: Adult; Aged; Amino Acids; Bicuspid; Borohydrides; Collagen; Cuspid; Dentin; Dipeptides; Female; Humans; Hydroxyproline; Incisor; Male; Middle Aged; Molar; Tooth	1993
Evaluation of bone turnover in type I osteoporosis using biochemical markers specific for both bone formation and bone resorption. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 1993, Volume: 3, Issue:5 Topics: Aged; Amino Acids; Biomarkers; Bone Development; Bone Resorption; Female; Humans; Hydroxyproline; Middle Aged; Osteocalcin; Osteoporosis, Postmenopausal; Postmenopause	1993
Immunoassay for urinary pyridinoline: the new marker of bone resorption. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1993, Volume: 8, Issue:5 Topics: Adult; Amino Acids; Biomarkers; Bone Resorption; Chromatography; Chromatography, High Pressure Liquid; Creatinine; Female; Humans; Hydrolysis; Hydroxyproline; Immunoenzyme Techniques; Male; Middle Aged	1993
Changes in (markers of) bone metabolism during high dose corticosteroid pulse treatment in patients with rheumatoid arthritis. Annals of the rheumatic diseases, 1996, Volume: 55, Issue:5 Topics: Acute Disease; Adult; Aged; Alkaline Phosphatase; Amino Acids; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Biomarkers; Bone and Bones; Bone Resorption; Calcium; Collagen; Collagen Type I; Dexamethasone; Drug Administration Schedule; Female; Humans; Hydroxyproline; Male; Middle Aged; Osteocalcin; Osteogenesis; Peptide Fragments; Peptides; Procollagen	1996
Altered x-ray diffraction pattern is accompanied by a change in the mode of cross-link formation in lipodermatosclerosis. The Journal of investigative dermatology, 1996, Volume: 107, Issue:4 Topics: Amino Acids; Biopsy; Collagen; Drug Residues; Humans; Hydroxylysine; Hydroxyproline; Leg; Reference Values; Scleroderma, Localized; Skin; X-Ray Diffraction	1996
Analysis of urinary pyridinoline and deoxypyridinoline in patients undergoing long-term anticonvulsant drug therapy. European neurology, 1996, Volume: 36, Issue:5 Topics: Adult; Alkaline Phosphatase; Amino Acids; Anticonvulsants; Calcium; Female; Humans; Hydroxyproline; Middle Aged; Reference Values; Time Factors	1996
New biochemical markers of bone resorption derived from collagen breakdown in the study of postmenopausal osteoporosis. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 1996, Volume: 6, Issue:4 Topics: Adult; Aged; Amino Acids; Biomarkers; Bone Diseases, Metabolic; Bone Resorption; Calcium; Collagen; Etidronic Acid; Female; Humans; Hydroxycholecalciferols; Hydroxyproline; Middle Aged; Osteoporosis, Postmenopausal; Peptide Fragments; Reference Values	1996
Comparative evaluation of markers of bone resorption in patients with breast cancer-induced osteolysis before and after bisphosphonate therapy. British journal of cancer, 1997, Volume: 75, Issue:3 Topics: Adult; Aged; Amino Acids; Analysis of Variance; Biomarkers; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Calcium; Diphosphonates; Female; Humans; Hydroxyproline; Middle Aged; Osteolysis; Pamidronate; Postmenopause; Regression Analysis	1997
Effect of an oral calcium load on urinary markers of collagen breakdown. Journal of endocrinological investigation, 1996, Volume: 19, Issue:11 Topics: Adult; Aged; Amino Acids; Calcium; Collagen; Creatinine; Female; Homeostasis; Humans; Hydroxylysine; Hydroxyproline; Middle Aged; Osteoclasts; Postmenopause	1996
Changes in biomechanical properties, composition of collagen and elastin, and advanced glycation endproducts of the rat aorta in relation to age. Atherosclerosis, 1996, Dec-20, Volume: 127, Issue:2 Topics: Aging; Amino Acids; Animals; Aorta, Thoracic; Biomarkers; Biomechanical Phenomena; Blood Pressure; Calcium; Chromatography, High Pressure Liquid; Collagen; Elasticity; Elastin; Glycation End Products, Advanced; Hydroxyproline; Male; Rats; Rats, Wistar	1996
Biochemical bone markers, bone mineral content, and bone mineral density in rats with experimental nephrotic syndrome. Renal failure, 1997, Volume: 19, Issue:3 Topics: Alkaline Phosphatase; Amino Acids; Animals; Biomarkers; Bone and Bones; Bone Density; Hydroxyproline; Male; Nephrotic Syndrome; Osteocalcin; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Wistar	1997
Is skeletal responsiveness to thyroid hormone altered in primary osteoporosis or following estrogen replacement therapy? Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1997, Volume: 12, Issue:1 Topics: Absorptiometry, Photon; Administration, Oral; Aged; Alkaline Phosphatase; Amino Acids; Bone Density; Bone Development; Bone Resorption; Calcium; Estrogen Replacement Therapy; Female; Follicle Stimulating Hormone; Forearm; Humans; Hydroxyproline; Lumbar Vertebrae; Middle Aged; Osteocalcin; Osteoporosis, Postmenopausal; Peptide Fragments; Postmenopause; Procollagen; Triiodothyronine	1997
A single measurement of biochemical markers of bone turnover has limited utility in the individual person. Scandinavian journal of clinical and laboratory investigation, 1997, Volume: 57, Issue:4 Topics: Adult; Alkaline Phosphatase; Amino Acids; Biomarkers; Bone Remodeling; Calcium; Creatinine; Female; Humans; Hydroxyproline; Middle Aged; Osteocalcin; Postmenopause; Premenopause; Reproducibility of Results	1997
The effect of gonadotropin-releasing hormone agonist on type I collagen C-telopeptide and N-telopeptide: the predictive value of biochemical markers of bone turnover. The Journal of clinical endocrinology and metabolism, 1998, Volume: 83, Issue:2 Topics: Adult; Alkaline Phosphatase; Amino Acids; Antineoplastic Agents, Hormonal; Biomarkers; Bone Remodeling; Buserelin; Collagen; Collagen Type I; Endometriosis; Estradiol; Female; Goserelin; Humans; Hydroxyproline; Leiomyoma; Osteocalcin; Peptides; Retrospective Studies	1998
Effects of tibolone (Org OD14) treatment for 3 months on ovariectomy-induced osteopenia in 8-month-old rats on a low-calcium diet: preventive testing for 3 months. Bone, 1998, Volume: 22, Issue:2 Topics: Administration, Oral; Amino Acids; Anabolic Agents; Animals; Antineoplastic Agents, Hormonal; Biomarkers; Bone Density; Bone Diseases, Metabolic; Bone Resorption; Calcium; Cholesterol; Creatinine; Female; Femur; Humans; Hydroxyproline; Lumbar Vertebrae; Norpregnenes; Osteocalcin; Ovariectomy; Rats; Rats, Sprague-Dawley; Weight Gain	1998
Gonadal status is an important determinant of bone density in acromegaly. Clinical endocrinology, 1998, Volume: 48, Issue:1 Topics: Acromegaly; Amino Acids; Biomarkers; Bone Density; Bone Remodeling; Case-Control Studies; Female; Femur Neck; Hormones; Humans; Hydroxyproline; Hypogonadism; Insulin-Like Growth Factor I; Lumbar Vertebrae; Male; Middle Aged; Octreotide; Osteocalcin; Parathyroid Hormone; Prospective Studies	1998
Collagen crosslinks in chondromalacia of the patella. International journal of sports medicine, 1998, Volume: 19, Issue:2 Topics: Adult; Amino Acids; Biomarkers; Cadaver; Cartilage Diseases; Cartilage, Articular; Collagen; Cross-Linking Reagents; Extracellular Matrix; Female; Humans; Hydroxyproline; Male; Microscopy, Polarization; Patella	1998
A proposal for standardizing urine collections for bone resorption markers measurement. Journal of clinical laboratory analysis, 1998, Volume: 12, Issue:3 Topics: Adult; Aged; Alkaline Phosphatase; Amino Acids; Biomarkers; Bone Density; Bone Resorption; Collagen; Collagen Type I; Female; Humans; Hydroxylysine; Hydroxyproline; Middle Aged; Osteocalcin; Peptide Fragments; Peptides	1998
Altered posttranslational modifications of collagen in keloid. Biochemical and biophysical research communications, 1998, Aug-28, Volume: 249, Issue:3 Topics: Adult; Amino Acids; Collagen; Cross-Linking Reagents; Desmosine; Dipeptides; Histidine; Humans; Hydroxylation; Hydroxylysine; Hydroxyproline; Keloid; Middle Aged; Protein Processing, Post-Translational; Protein Structure, Secondary; Skin	1998
Urinary collagen crosslinks reflect further bone loss of femoral neck in osteoporotic patients undergoing vitamin D therapy. Endocrine research, 1998, Volume: 24, Issue:2 Topics: Alkaline Phosphatase; Amino Acids; Analysis of Variance; Biomarkers; Bone Density; Bone Resorption; Chromatography, High Pressure Liquid; Female; Femur Neck; Humans; Hydroxyproline; Lumbar Vertebrae; Osteoporosis; Vitamin D	1998
Prenylflavonoids: a new class of non-steroidal phytoestrogen (Part 2). Estrogenic effects of 8-isopentenylnaringenin on bone metabolism. Planta medica, 1998, Volume: 64, Issue:6 Topics: Amino Acids; Animals; Biomarkers; Bone Density; Bone Resorption; Estradiol; Estrogens, Non-Steroidal; Female; Hydroxyproline; Isoflavones; Organ Size; Ovariectomy; Phytoestrogens; Plant Preparations; Rats; Rats, Sprague-Dawley; Tibia; Uterus	1998
[Determination of bone markers in dairy cows with parturient paresis]. Schweizer Archiv fur Tierheilkunde, 1998, Volume: 140, Issue:10 Topics: Amino Acids; Animals; Biomarkers; Bone and Bones; Calcium; Cattle; Cattle Diseases; Female; Hydroxyproline; Parturient Paresis; Pregnancy	1998
Pyridinoline in relation to ultimate stress of the patellar tendon during healing: an animal study. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 1998, Volume: 16, Issue:5 Topics: Amino Acids; Animals; Biomarkers; Biomechanical Phenomena; Collagen; Hydroxyproline; Knee Joint; Male; Patella; Rats; Rats, Sprague-Dawley; Stress, Mechanical; Tendon Injuries; Tendons; Tibia; Wound Healing	1998
Comparison of urinary bone resorption markers in women of 40-70 years; day-to-day and long-term variation in individual subjects. Maturitas, 1998, Nov-16, Volume: 30, Issue:3 Topics: Adult; Age Factors; Aged; Amino Acids; Biomarkers; Bone Resorption; Collagen; Collagen Type I; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hydroxyproline; Middle Aged; Osteoporosis, Postmenopausal; Peptides; Time Factors	1998
Collagen cross-links in fibromyalgia syndrome. Zeitschrift fur Rheumatologie, 1998, Volume: 57 Suppl 2 Topics: Amino Acids; Axons; Collagen; Collagen Diseases; Connective Tissue; Fibromyalgia; Humans; Hydroxyproline; Microscopy, Electron; Nerve Fibers; Reference Values; Skin	1998
Investigations of bone turnover in renal osteopathy. European journal of medical research, 1999, Feb-25, Volume: 4, Issue:2 Topics: Adult; Aged; Amino Acids; Biomarkers; Bone Remodeling; Bone Resorption; Calcium; Chromatography, High Pressure Liquid; Chronic Kidney Disease-Mineral and Bone Disorder; Female; Humans; Hydroxyproline; Kidney Failure, Chronic; Male; Middle Aged; Osteocalcin; Renal Dialysis	1999
The effect of toremifene on bone and uterine histology and on bone resorption in ovariectomised rats. Pharmacology & toxicology, 1999, Volume: 84, Issue:2 Topics: Amino Acids; Animals; Biomarkers; Bone and Bones; Bone Resorption; Calcium; Drug Interactions; Estradiol; Estrogen Antagonists; Female; Hydroxyproline; In Vitro Techniques; Ovariectomy; Random Allocation; Rats; Rats, Sprague-Dawley; Toremifene; Uterus	1999
[Effect of KW-8232 on bone turnover in ovariectomized rats]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1998, Volume: 112, Issue:5 Topics: Alkaline Phosphatase; Amino Acids; Animals; Bone Density; Bone Resorption; Calcium; Disease Models, Animal; Female; Humans; Hydroxyproline; Indoles; Mesylates; Osteocalcin; Osteoporosis, Postmenopausal; Ovariectomy; Rats; Rats, Sprague-Dawley	1998
Big future in store for biochemical bone markers. CAP today, 1996, Volume: 10, Issue:2 Topics: Alkaline Phosphatase; Amino Acids; Biomarkers; Bone Resorption; Humans; Hydroxyproline; Osteoporosis	1996
Persistence of bone collagen cross-links in skeletons of the Nuraghi population living in Sardinia 1500-1200 B.C. Calcified tissue international, 1999, Volume: 64, Issue:5 Topics: Amino Acids; Chromatography, High Pressure Liquid; Collagen; Dipeptides; History, Ancient; Humans; Hydroxyproline; Italy; Male; Microscopy, Polarization; Paleopathology; Tibia	1999
Remobilization does not fully restore immobilization induced articular cartilage atrophy. Clinical orthopaedics and related research, 1999, Issue:362 Topics: Amino Acids; Animals; Atrophy; Biomechanical Phenomena; Cartilage, Articular; Case-Control Studies; Collagen; Coloring Agents; Dogs; Female; Femur; Glycosaminoglycans; Hindlimb; Hydroxyproline; Immobilization; Microscopy, Polarization; Microspectrophotometry; Movement; Phenazines; Proteoglycans; Radiopharmaceuticals; Recovery of Function; Sulfur Radioisotopes; Tibia; Weight-Bearing	1999
Determination of fibrosis from cryostat sections using high performance liquid chromatography: skeletal muscle. The Histochemical journal, 1999, Volume: 31, Issue:2 Topics: Amino Acids; Animals; Chromatography, High Pressure Liquid; Collagen; Female; Fibronectins; Fibrosis; Frozen Sections; Hydroxyproline; Immunohistochemistry; Muscle Denervation; Muscle, Skeletal; Myosins; Rats; Rats, Sprague-Dawley	1999
Osteogenesis imperfecta: bone turnover, bone density, and ultrasound parameters. Calcified tissue international, 1999, Volume: 65, Issue:2 Topics: Absorptiometry, Photon; Adult; Alkaline Phosphatase; Amino Acids; Bone and Bones; Bone Density; Bone Resorption; Calcaneus; Female; Fingers; Humans; Hydroxyproline; Lumbar Vertebrae; Male; Osteocalcin; Osteogenesis Imperfecta; Peptide Fragments; Procollagen; Radius; Ultrasonography	1999
Diurnal variation in concentrations of various markers of bone metabolism in dogs. American journal of veterinary research, 1999, Volume: 60, Issue:8 Topics: Alkaline Phosphatase; Amino Acids; Animals; Biomarkers; Blood Chemical Analysis; Bone and Bones; Chromatography, High Pressure Liquid; Circadian Rhythm; Collagen; Collagen Type I; Colorimetry; Creatinine; Dogs; Female; Hydroxyproline; Osteocalcin; Peptides; Radioimmunoassay; Reference Values	1999
Biochemical markers of bone turnover after surgical menopause and hormone replacement therapy. Bone, 1999, Volume: 25, Issue:3 Topics: Acid Phosphatase; Administration, Cutaneous; Alkaline Phosphatase; Amino Acids; Biomarkers; Bone Development; Bone Resorption; Collagen; Collagen Type I; Estradiol; Estrogen Replacement Therapy; Female; Humans; Hydroxyproline; Isoenzymes; Menopause, Premature; Middle Aged; Osteocalcin; Ovariectomy; Peptide Fragments; Peptides; Procollagen; Tartrate-Resistant Acid Phosphatase	1999
Functional adaptation of equine articular cartilage: the formation of regional biochemical characteristics up to age one year. Equine veterinary journal, 2000, Volume: 32, Issue:3 Topics: Age Factors; Amino Acids; Animals; Animals, Newborn; Bisbenzimidazole; Cartilage, Articular; Chromatography, High Pressure Liquid; Collagen; DNA; Glycosaminoglycans; Horses; Hydroxylysine; Hydroxyproline; Joints; Methylene Blue; Statistics, Nonparametric; Water	2000
Three-dimensional cultivation of human osteoblast-like cells on highly porous natural bone mineral. Journal of biomedical materials research, 2000, Sep-15, Volume: 51, Issue:4 Topics: Amino Acids; Biomedical Engineering; Bone and Bones; Bone Matrix; Bone Substitutes; Cell Culture Techniques; Cell Division; Collagen; Extracellular Matrix; Humans; Hydroxyproline; Materials Testing; Microscopy, Electron; Microscopy, Electron, Scanning; Minerals; Osteoblasts; Surface Properties	2000
Elevated protein content and prolyl 4-hydroxylase activity in severely degenerated human annulus fibrosus. Connective tissue research, 2000, Volume: 41, Issue:2 Topics: Adult; Amino Acids; Collagen; Humans; Hydroxyproline; Intervertebral Disc; Middle Aged; Procollagen-Proline Dioxygenase; Protein Processing, Post-Translational; Proteins; Spinal Diseases	2000
[Laboratory diagnosis of osteoporosis]. Der Orthopade, 2001, Volume: 30, Issue:7 Topics: Adult; Aged; Alkaline Phosphatase; Amino Acids; Biomarkers; Bone and Bones; Bone Resorption; Child; Clinical Enzyme Tests; Diagnosis, Differential; Diphosphonates; Female; Humans; Hydroxyproline; Immunoassay; Male; Middle Aged; Osteocalcin; Osteoporosis; Osteoporosis, Postmenopausal; Procollagen; Sensitivity and Specificity	2001
Evaluation of bone and collagen metabolism by assessing urinary biomarkers in non-human primates. Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology, 2000, Volume: 7, Issue:1 Topics: Amino Acids; Animals; Biomarkers; Bone and Bones; Calcium; Collagen; Creatinine; Hydroxyproline; Macaca mulatta; Male; Osteocalcin; Space Flight; Weightlessness	2000
Bone biochemistry in rat femoral diaphysis after space flight. Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology, 2000, Volume: 7, Issue:3 Topics: Amino Acids; Animals; Calcification, Physiologic; Calcium; Collagen; Diaphyses; Femur; Hindlimb Suspension; Hydroxyproline; Male; Osteocalcin; Phosphorus; Rats; Rats, Wistar; Space Flight; Weightlessness; Weightlessness Simulation	2000
Bone resorption versus estrogen loss following oophorectomy and menopause. Maturitas, 2002, Sep-30, Volume: 43, Issue:1 Topics: Amino Acids; Biomarkers; Bone Density; Bone Resorption; Calcium; Collagen Type I; Creatinine; Estradiol; Female; Humans; Hydroxyproline; Lumbar Vertebrae; Middle Aged; Osteoporosis, Postmenopausal; Ovariectomy; Peptide Fragments; Peptides; Procollagen	2002
Extracellular matrix maturation in the left ventricle of normal and diabetic swine. Diabetes research and clinical practice, 2003, Volume: 59, Issue:1 Topics: Amino Acids; Animals; Chromatography, High Pressure Liquid; Collagen; Diabetes Mellitus, Experimental; Extracellular Matrix; Hydroxyproline; Imino Acids; Male; Myocardium; Swine; Swine, Miniature; Tissue Distribution; Ventricular Function, Left	2003
Unloading-induced remodeling in the normal and hypertrophic left ventricle. American journal of physiology. Heart and circulatory physiology, 2003, Volume: 284, Issue:6 Topics: Algorithms; Amino Acids; Animals; Blotting, Western; Cell Separation; Echocardiography; Gelatin; Heart Transplantation; Heart Ventricles; Hydroxyproline; Hypertrophy, Left Ventricular; Myocardium; Proteins; Rats; Rats, Inbred Lew; Ventricular Function; Ventricular Remodeling	2003
Progressive adult-onset emphysema in transgenic mice expressing human MMP-1 in the lung. American journal of physiology. Lung cellular and molecular physiology, 2003, Volume: 284, Issue:5 Topics: Acute Disease; Age of Onset; Amino Acids; Animals; Bronchoalveolar Lavage Fluid; Collagen Type I; Collagen Type III; Elastin; Emphysema; Extracellular Matrix; Gene Expression Regulation, Enzymologic; Humans; Hydroxyproline; Immunohistochemistry; Leukocyte Count; Lung; Lung Compliance; Matrix Metalloproteinase 1; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Transgenes	2003
Biochemical markers of bone metabolism in infants and children under intravenous corticosteroid therapy. Calcified tissue international, 2003, Volume: 73, Issue:4 Topics: Alkaline Phosphatase; Amino Acids; Anti-Inflammatory Agents; Biomarkers; Bone and Bones; Calcium; Child; Child, Preschool; Female; Humans; Hydrocortisone; Hydroxyproline; Infant; Injections, Intravenous; Male; Methylprednisolone; Osteocalcin; Respiratory Tract Diseases	2003
Effect of shock-wave therapy on patellar tendinopathy in a rabbit model. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2004, Volume: 22, Issue:1 Topics: Amino Acids; Animals; Collagenases; Hydroxyproline; Male; Patella; Rabbits; Tendinopathy; Tendons; Tensile Strength; Ultrasonic Therapy; Weight-Bearing	2004
[Normal values of bone turnover markers in childhood]. Anales de pediatria (Barcelona, Spain : 2003), 2004, Volume: 60, Issue:4 Topics: Adolescent; Amino Acids; Bone and Bones; Child; Child, Preschool; Humans; Hydroxyproline; Infant; Osteocalcin; Peptide Fragments; Procollagen; Reference Values; Spain	2004
Ultrasound measurement of pregnancy-induced changes in maternal bone mass: a longitudinal, cross-sectional and biochemical study. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2004, Volume: 18, Issue:5 Topics: Adult; Amino Acids; Biomarkers; Bone and Bones; Bone Density; Bone Remodeling; Calcium, Dietary; Cross-Sectional Studies; Female; Fingers; Humans; Hydroxyproline; Longitudinal Studies; Pregnancy; Ultrasonography	2004
Reduced collagen and ascorbic acid concentrations and increased proteolytic susceptibility with prelabor fetal membrane rupture in women. Biology of reproduction, 2005, Volume: 72, Issue:1 Topics: Adult; Amino Acids; Ascorbic Acid; Case-Control Studies; Collagen; Disease Susceptibility; Extraembryonic Membranes; Female; Fetal Membranes, Premature Rupture; Humans; Hydroxyproline; Infant, Newborn; Malondialdehyde; Oxidative Stress; Pregnancy; Proteins; Reference Values	2005
Detection of mature collagen in human dental enamel. Calcified tissue international, 2005, Volume: 76, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amino Acids; Biomarkers; Chromatography, High Pressure Liquid; Collagen; Dental Enamel; Dentin; Electrophoresis, Polyacrylamide Gel; Humans; Hydroxyproline; Middle Aged; Spectrophotometry; Tooth	2005
The biphasic response of porcine tendon to recombinant porcine growth hormone. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, 2005, Volume: 15, Issue:1 Topics: Adipose Tissue; Amino Acids; Animals; Body Weight; Cell Differentiation; Cell Proliferation; Cross-Linking Reagents; Crosses, Genetic; DNA; Extracellular Matrix; Growth Hormone; Hydroxyproline; Papain; Proteoglycans; Recombinant Proteins; Swine; Tendons; Time Factors; Uronic Acids	2005
Accelerated bone turnover in pregnant women with McCune-Albright syndrome. Gynecologic and obstetric investigation, 2005, Volume: 60, Issue:2 Topics: Adult; Alkaline Phosphatase; Amino Acids; Bone Remodeling; Calcitonin; Calcium; Female; Fibrous Dysplasia, Polyostotic; Humans; Hydroxyproline; Infant; Male; Osteocalcin; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Phosphorus; Pregnancy; Pregnancy Complications; Vitamin D	2005
The effect of hyaluronic acid with different molecular weights on collagen crosslink synthesis in cultured chondrocytes embedded in collagen gels. Journal of biomedical materials research. Part A, 2005, Nov-01, Volume: 75, Issue:2 Topics: Amino Acids; Animals; Cartilage; Cells, Cultured; Chondrocytes; Collagen; Extracellular Matrix; Gels; Hyaluronic Acid; Hydroxyproline; Molecular Weight; Rabbits	2005
Biochemical study of collagen and its crosslinks in the anterior cruciate ligament and the tissues used as a graft for reconstruction of the anterior cruciate ligament. Connective tissue research, 2008, Volume: 49, Issue:1 Topics: Age Factors; Amino Acids; Anterior Cruciate Ligament; Arginine; Chromatography, High Pressure Liquid; Collagen; Elastin; Humans; Hydroxyproline; Lysine; Patellar Ligament	2008
Impaired pyridinoline cross-link formation in patients with osteogenesis imperfecta. Journal of bone and mineral metabolism, 2008, Volume: 26, Issue:4 Topics: Amino Acids; Case-Control Studies; Child; Child, Preschool; Collagen Type I; Cross-Linking Reagents; Female; Humans; Hydroxyproline; Male; Osteogenesis Imperfecta; Peptides	2008
A noninvasive analysis of urinary musculoskeletal collagen metabolism markers from rhesus monkeys subject to chronic hypergravity. Journal of applied physiology (Bethesda, Md. : 1985), 2008, Volume: 105, Issue:4 Topics: Adaptation, Physiological; Amino Acids; Animals; Biomarkers; Calcium; Centrifugation; Collagen; Creatinine; Eating; Hydroxyproline; Hypergravity; Macaca mulatta; Musculoskeletal System; Time Factors; Urinalysis; Weightlessness Countermeasures	2008
Impact of sex and chronic resistance training on human patellar tendon dry mass, collagen content, and collagen cross-linking. American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 296, Issue:1 Topics: Adult; Amino Acids; Biopsy; Body Water; Collagen; Female; Humans; Hydroxyproline; Male; Organ Size; Patellar Ligament; Resistance Training; Sex Factors; Young Adult	2009
Detection of unsaturated disaccharides, pyridinoline, and hydroxyproline in urine of patients with Kashin-Beck disease: comparison with controls in an endemic area. The Journal of rheumatology, 2009, Volume: 36, Issue:4 Topics: Adult; Amino Acids; Biomarkers; China; Disaccharides; Endemic Diseases; Female; Humans; Hydroxyproline; Joint Diseases; Male	2009
Mechanical properties and collagen cross-linking of the patellar tendon in old and young men. Journal of applied physiology (Bethesda, Md. : 1985), 2009, Volume: 107, Issue:3 Topics: Adult; Aged; Aging; Amino Acids; Arginine; Arm; Biomechanical Phenomena; Biopsy; Collagen; Glycation End Products, Advanced; Humans; Hydroxyproline; Knee; Lysine; Male; Movement; Muscle, Skeletal; Patellar Ligament; Protein-Lysine 6-Oxidase	2009
Caprine articular, meniscus and intervertebral disc cartilage: an integral analysis of collagen network and chondrocytes. Matrix biology : journal of the International Society for Matrix Biology, 2010, Volume: 29, Issue:3 Topics: Amino Acids; Animals; Cartilage, Articular; Cell Survival; Chondrocytes; Coculture Techniques; Collagen; Female; Gene Expression Profiling; Goats; Hydroxylysine; Hydroxyproline; Intervertebral Disc; Menisci, Tibial; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tissue Engineering	2010
UPLC methodology for identification and quantitation of naturally fluorescent crosslinks in proteins: a study of bone collagen. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011, Feb-15, Volume: 879, Issue:5-6 Topics: Adult; Aged; Aged, 80 and over; Amino Acids; Chromatography, High Pressure Liquid; Collagen; Humans; Hydroxyproline; Linear Models; Middle Aged; Models, Chemical; Reproducibility of Results; Spectrometry, Fluorescence; Tibia	2011
Effects of zoledronate on irradiated bone in vivo: analysis of the collagen types I, V and their cross-links lysylpyridinoline, hydroxylysylpyridinoline and hydroxyproline. Calcified tissue international, 2013, Volume: 92, Issue:3 Topics: Amino Acids; Animals; Bone and Bones; Bone Density Conservation Agents; Chromatography, High Pressure Liquid; Collagen Type I; Collagen Type V; Diphosphonates; Electrophoresis, Polyacrylamide Gel; Hydroxyproline; Imidazoles; Male; Rats; Rats, Wistar; Zoledronic Acid	2013
The effect of chronic treadmill exercise and acetaminophen on collagen and cross-linking in rat skeletal muscle and heart. American journal of physiology. Regulatory, integrative and comparative physiology, 2015, Feb-15, Volume: 308, Issue:4 Topics: Acetaminophen; Amino Acids; Analgesics; Animals; Antipyretics; Collagen; Hydroxyproline; Male; Muscle, Skeletal; Myocardium; Physical Exertion; Rats, Wistar; Running; Sedentary Behavior; Time Factors	2015
Inhibitory effects of alkaline extract from the pericarp of Citrus reticulata Blanco on collagen behavior in bleomycin-induced pulmonary fibrosis. Journal of ethnopharmacology, 2021, Apr-06, Volume: 269 Topics: Administration, Oral; Alkalies; Amino Acid Oxidoreductases; Amino Acids; Animals; Bleomycin; Citrus; Collagen Type I; Collagen Type III; Disease Models, Animal; Down-Regulation; Extracellular Matrix Proteins; Hydroxyproline; Mice, Inbred C57BL; Plant Extracts; Protein-Lysine 6-Oxidase; Pulmonary Fibrosis; Smad3 Protein; Transforming Growth Factor beta1	2021