hydroxyproline has been researched along with dimethylnitrosamine in 48 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (6.25) | 18.7374 |
| 1990's | 6 (12.50) | 18.2507 |
| 2000's | 18 (37.50) | 29.6817 |
| 2010's | 21 (43.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bills, DD; Nixon, JE; Scanlan, RA; Sinnhuber, RO; Wales, JH | 1 |
| Ala-Kokko, L; Günzler, V; Hoek, JB; Prockop, DJ; Rubin, E | 1 |
| Fujiwara, K; Mochida, S; Ogata, I; Tomiya, T | 1 |
| Fujiwara, K; Ogata, I | 1 |
| Asakura, H; Ichida, T; Komoriya, Y; Matsuda, Y; Matsumoto, K; Nakamura, T; Nishiyama, E; Yamada, A | 1 |
| Fujise, N; Higashio, K; Masunaga, H; Ogawa, H; Shiota, A; Yamashita, Y; Yasuda, H | 1 |
| Cho, JJ; Lee, YS | 1 |
| Gertman, PM; Madden, JW; Peacock, EE | 1 |
| Kyotani, S; Miyamura, M; Nishioka, Y; Ohnishi, S; Ono, M; Saibara, T | 1 |
| Chandrakasan, G; George, J | 1 |
| Enjoji, M; Iwamoto, H; Nakamuta, M; Nakashima, Y; Nawata, H; Sugimoto, R; Tada, S | 1 |
| Enjoji, M; Iwamoto, H; Kato, M; Nakamuta, M; Nakashima, Y; Nawata, H; Sugimoto, R; Tada, S | 1 |
| Chen, W; Hu, Y; Liu, C; Liu, P; Wang, Z | 1 |
| Enjoji, M; Kato, M; Kotoh, K; Nakamuta, M; Nakashima, Y; Nawata, H; Ohta, S; Sugimoto, R; Tada, S; Tsuruta, S | 1 |
| Cai, WM; Liu, RH; Weng, HL | 1 |
| Etani, Y; Kondou, H; Michigami, T; Miyoshi, Y; Mushiake, S; Ozono, K | 1 |
| Aydin, S; Aytekin, H; Canbakan, B; Mert, A; Ozaras, R; Ozbay, G; Senturk, H; Tahan, V; Uzun, H; Yildirim, B | 1 |
| Cui, HY; Hu, YY; Jiang, ZH; Li, FH; Liu, C; Liu, CH; Liu, P; Xu, LM; Yuan, JL | 1 |
| Hu, YY; Liu, CH; Liu, P; Wang, XN; Zhu, DY | 1 |
| Cho, CK; Cho, JH; Han, SH; Hu, XP; Lee, MM; Lee, YW; Oh, SM; Shin, JW; Son, CG; Son, JY; Wang, JH; Yoo, HS | 1 |
| Li, XM; Wang, BE; Wang, TL; Zhao, XY | 1 |
| Li, FH; Liu, P; Xiong, WG; Xu, GF | 1 |
| Chen, Y; Ge, WH; He, JY | 1 |
| Jung, HS; Kim, EK; Kim, EY; Lee, HS; Soh, Y; Sohn, NW; Sohn, Y | 1 |
| Chen, CF; Horng, LY; Huang, CH; Wu, RT | 1 |
| Ha, JR; Kim, DH; Kim, DY; Oh, SW | 1 |
| Cho, HY; Kim, HK; Yang, TH | 1 |
| De Mey, E; Dejaegher, B; Drabik-Markiewicz, G; Impens, S; Kowalska, T; Paelinck, H; Vander Heyden, Y | 1 |
| Huang, HF; Lei, CL; Li, CQ; Li, WL; Li, XY; Tan, XH; Xie, M; Zhang, AM; Zou, SR | 1 |
| Kang, JK; Shin, JW; Son, CG; Wang, JH | 1 |
| Chen, GF; Lu, Y; Tong, X | 1 |
| Duan, X; Feng, Q; Fu, Q; Hu, Y; Li, X; Peng, J | 1 |
| Chen, GF; Chen, JM; Liu, P; Mu, YP; Ning, BB; Ren, S; Zhang, H; Zhang, LJ; Zhang, WM; Zhang, X | 1 |
| Chen, X; Liu, C; Lu, L; Lu, Y; Lv, Z; Pan, Q; Xu, Q; Yang, Z | 1 |
| Bian, YQ; Cao, HY; Chen, GF; Liu, C; Liu, J; Liu, P; Lu, Y; Ning, BB; Sun, MY | 1 |
| Feng, Q; Hu, YY; Li, XM; Peng, JH | 1 |
| Bai, HB; Fu, XC; Hu, R; Qian, Y; Shen, LM | 1 |
| Chen, SW; Chen, YX; Fan, TT; Lv, J; Qian, H; Shi, J; Song, CY; Xie, WF; Zheng, ZW | 1 |
| Chen, CM; Chen, HL; Cheng, WT; Chong, KY; Tang, TY; Tung, YT; Yang, SH | 1 |
| Duan, B; Mu, W; Qiu, B; Qiu, W; Shi, C; Sun, X; Wang, X; Wei, F; Zhang, J | 1 |
| Endo, K; Hori, T; Iwaisako, K; Jobara, K; Kaido, T; Uchida, Y; Uemoto, S | 1 |
| Chen, BM; Chen, X; He, M; Li, CY; Liu, LQ; Wang, YH; Zhao, CX | 1 |
| Chen, X; Liu, C; Lu, Y; Miao, H; Tang, B; Wang, L; Xu, Q; Yang, Z | 1 |
| Li, D; Li, J; Liu, M; Liu, Y; Liu, Z; Ren, G; Song, L; Xu, P; Yang, Y; Yuan, Q; Zhang, Y | 1 |
| Bak, J; Cheong, KO; Chung, HY; Je, NK; Kim, KW; Lee, C; Moon, JO; Shin, DS; Yoon, S | 1 |
| Chen, QL; Liu, P; Lu, YY; Song, YN; Su, SB; Wang, ZT; Yang, L; Zhang, GB | 1 |
| Chen, G; Chen, J; Liu, P; Mu, Y; Ren, S; Sun, M; Tong, X; Wang, X; Zhang, H; Zhou, Y | 1 |
| Chen, GF; Cheng, Y; Mai, JY; Ping, J; Wang, MF | 1 |
1 trial(s) available for hydroxyproline and dimethylnitrosamine
| Article | Year |
|---|---|
Animal experiment and clinical study of effect of gamma-interferon on hepatic fibrosis.
Topics: Animals; Antineoplastic Agents; Biopsy; Carbon Tetrachloride; Dimethylnitrosamine; Disease Models, Animal; Female; Hepatitis B, Chronic; Humans; Hyaluronic Acid; Hydroxyproline; Interferon-gamma; Liver; Liver Cirrhosis; Liver Function Tests; Male; Rats; Rats, Sprague-Dawley; Recombinant Proteins | 2001 |
47 other study(ies) available for hydroxyproline and dimethylnitrosamine
| Article | Year |
|---|---|
Null carcinogenic effect of large doses of nitrosoproline and nitrosohydroxyproline in Wistar rats.
Topics: Animals; Carcinoma, Hepatocellular; Dimethylnitrosamine; Drug Synergism; Fatty Acids, Unsaturated; Hydroxyproline; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Proline; Rats | 1976 |
Hepatic fibrosis in rats produced by carbon tetrachloride and dimethylnitrosamine: observations suggesting immunoassays of serum for the 7S fragment of type IV collagen are a more sensitive index of liver damage than immunoassays for the NH2-terminal prop
Topics: Animals; Biomarkers; Carbon Tetrachloride Poisoning; Collagen; Dimethylnitrosamine; Female; Fibrosis; Hydroxyproline; Immunoassay; Inflammation; Liver; Liver Cirrhosis, Experimental; Macromolecular Substances; Peptide Fragments; Procollagen; Rats; Rats, Inbred Strains; Reference Values; RNA, Messenger | 1992 |
Minor contribution of hepatocytes to collagen production in normal and early fibrotic rat livers.
Topics: Amino Acids; Animals; Carbon Tetrachloride; Collagen; Dimethylnitrosamine; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Male; Protein Biosynthesis; Rats; Rats, Inbred F344; Reference Values; Serum Albumin; Time Factors | 1991 |
Collagen accumulation can continue with decreased prolyl hydroxylase activity in the liver.
Topics: Alanine Transaminase; Animals; Collagen; Dimethylnitrosamine; Dose-Response Relationship, Drug; Hydroxyproline; Liver; Male; Necrosis; Procollagen-Proline Dioxygenase; Rats; Rats, Inbred Strains | 1985 |
Preventive and therapeutic effects in rats of hepatocyte growth factor infusion on liver fibrosis/cirrhosis.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Carbon Tetrachloride; Dimethylnitrosamine; Fibrinogen; Hepatocyte Growth Factor; Humans; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Male; Organ Size; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Serum Albumin; Survival Rate | 1997 |
Effects of the deleted form of hepatocyte growth factor on serum hyaluronate levels in rats with liver cirrhosis.
Topics: Animals; Carbon Tetrachloride; Dimethylnitrosamine; Hepatocyte Growth Factor; Humans; Hyaluronic Acid; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Liver Function Tests; Male; Organ Size; Prothrombin Time; Rats; Rats, Wistar; Recombinant Proteins; Sequence Deletion | 1998 |
Enzyme-linked immunosorbent assay for serum procollagen type III peptide in rats with hepatic fibrosis.
Topics: Animals; Bile Ducts; Biomarkers; Dimethylnitrosamine; Enzyme-Linked Immunosorbent Assay; Hydroxyproline; Ligation; Liver; Liver Cirrhosis, Experimental; Male; Organ Size; Peptide Fragments; Procollagen; Rats; Rats, Sprague-Dawley | 1998 |
Dimethylnitrosamine-induced hepatic cirrhosis: a new canine model of an ancient human disease.
Topics: Animals; Dimethylnitrosamine; Disease Models, Animal; Dogs; Female; Humans; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Lymphatic System; Male; Portal System | 1970 |
Effects of Sho-saiko-to extract on liver fibrosis in relation to the changes in hydroxyproline and retinoid levels of the liver in rats.
Topics: Administration, Oral; Animals; Dimethylnitrosamine; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Hydroxyproline; Hypolipidemic Agents; Liver Cirrhosis, Experimental; Male; Rats; Rats, Wistar; Retinoids | 1999 |
Biochemical abnormalities during the progression of hepatic fibrosis induced by dimethylnitrosamine.
Topics: Animals; Blood Glucose; Cholesterol; Creatinine; Dimethylnitrosamine; Fibrosis; Hydroxyproline; Insulin; Lipid Peroxides; Liver; Male; Phosphates; Rats; Rats, Wistar; Time Factors; Urea; Uric Acid | 2000 |
A selective ROCK inhibitor, Y27632, prevents dimethylnitrosamine-induced hepatic fibrosis in rats.
Topics: Actins; Amides; Animals; Body Weight; Collagen; Dimethylnitrosamine; Enzyme Inhibitors; Hydroxyproline; Intracellular Signaling Peptides and Proteins; Liver; Liver Cirrhosis; Male; Muscle, Smooth; Organ Size; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Wistar; rho-Associated Kinases; RNA, Messenger | 2001 |
Pirfenidone inhibits dimethylnitrosamine-induced hepatic fibrosis in rats.
Topics: Animals; Blotting, Northern; Body Weight; Collagen; Dimethylnitrosamine; Hydroxyproline; Liver Cirrhosis; Male; Pyridones; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transforming Growth Factor beta | 2001 |
[Changes of lipid peroxidation in liver fibrogenesis induced by dimethylnitrosamine and drugs' intervention].
Topics: Animals; Dimethylnitrosamine; Hydroxyproline; Interferon-gamma; Lipid Peroxidation; Liver Cirrhosis, Experimental; Male; Rats; Rats, Wistar; Superoxide Dismutase | 2001 |
Dimethyl sulfoxide inhibits dimethylnitrosamine-induced hepatic fibrosis in rats.
Topics: Animals; Body Weight; Cell Line; Cells, Cultured; Chemical and Drug Induced Liver Injury; Collagen Type I; Dimethyl Sulfoxide; Dimethylnitrosamine; Fibrosis; Free Radical Scavengers; Gene Expression Regulation; Hydroxyproline; Kupffer Cells; Lipopolysaccharides; Liver; Liver Diseases; Luciferases; Male; NF-kappa B; Nitric Oxide; Organ Size; Promoter Regions, Genetic; Rats; Rats, Wistar; Recombinant Fusion Proteins; RNA, Messenger; Severity of Illness Index; Tumor Necrosis Factor-alpha; Weight Loss | 2001 |
A blocking peptide for transforming growth factor-beta1 activation prevents hepatic fibrosis in vivo.
Topics: Animals; Atrophy; Dimethylnitrosamine; Disease Progression; DNA-Binding Proteins; Hydroxyproline; Liver; Liver Cirrhosis; Male; Necrosis; Peptides; Phosphorylation; Rats; Rats, Sprague-Dawley; Smad2 Protein; Trans-Activators; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2003 |
Melatonin reduces dimethylnitrosamine-induced liver fibrosis in rats.
Topics: Animals; Antioxidants; Dimethylnitrosamine; Glutathione; Hydroxyproline; Lipid Peroxidation; Liver Cirrhosis; Liver Function Tests; Male; Malondialdehyde; Melatonin; Rats; Rats, Wistar; Superoxide Dismutase | 2004 |
[Effects of Fuzheng Huayu recipe on renal toxic interstitial fibrosis in rats].
Topics: Animals; Creatinine; Dimethylnitrosamine; Disease Models, Animal; Drugs, Chinese Herbal; Fibrosis; Hydroxyproline; Kidney; Male; Nephritis, Interstitial; Rats; Rats, Wistar; Renal Insufficiency | 2004 |
[Effects of salvianolic acid B on expressions of TGF-beta1 and its receptors in liver of rats with dimethylnitrosamine-induced hepatic fibrosis].
Topics: Animals; Benzofurans; Collagen Type I; Dimethylnitrosamine; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Male; Protein Serine-Threonine Kinases; Random Allocation; Rats; Rats, Wistar; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
An herbal formula, CGX, exerts hepatotherapeutic effects on dimethylnitrosamine-induced chronic liver injury model in rats.
Topics: Animals; Dimethylnitrosamine; Drugs, Chinese Herbal; Gene Expression; Hydroxyproline; Lipid Peroxidation; Liver; Liver Cirrhosis; Liver Diseases; Male; Organ Size; Rats; Rats, Wistar; Spleen | 2006 |
[Inhibitory effects of silymarin on hepatic fibrosis induced by dimethylnitrosamine: experiment with rats].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bilirubin; Dimethylnitrosamine; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Liver Function Tests; Male; Protective Agents; Random Allocation; Rats; Rats, Wistar; Serum Albumin; Silymarin | 2006 |
[Effects of corydyceps polysaccharide on liver fibrosis induced by DMN in rats].
Topics: Animals; Collagen Type IV; Cordyceps; Dimethylnitrosamine; Hydroxyproline; Liver; Liver Cirrhosis; Male; Malondialdehyde; Matrix Metalloproteinase 2; Polysaccharides; Random Allocation; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Tissue Inhibitor of Metalloproteinase-2 | 2006 |
Iron deposition and fat accumulation in dimethylnitrosamine-induced liver fibrosis in rat.
Topics: Alanine Transaminase; Animals; Collagen; Dimethylnitrosamine; Female; Hydroxyproline; Iron; Lipid Metabolism; Liver; Liver Cirrhosis; Male; Random Allocation; Rats; Rats, Sprague-Dawley | 2007 |
Protective effects of Cuscutae semen against dimethylnitrosamine-induced acute liver injury in Sprague-Dawley rats.
Topics: Actins; Alkylating Agents; Animals; Blotting, Western; Body Weight; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Dimethylnitrosamine; Hydroxyproline; Image Processing, Computer-Assisted; Immunohistochemistry; Indicators and Reagents; Liver; Male; Organ Size; Plants, Medicinal; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Reference Standards | 2007 |
Chinese herb Radix Polygoni Multiflori as a therapeutic drug for liver cirrhosis in mice.
Topics: Alkylating Agents; Animals; Cell Proliferation; Cell Separation; Cell Survival; Chromatography, High Pressure Liquid; Coculture Techniques; Collagen; Dimethylnitrosamine; Drugs, Chinese Herbal; Glyceraldehyde-3-Phosphate Dehydrogenases; Hepatocyte Growth Factor; Hepatocytes; Hydroxyproline; Kupffer Cells; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Phagocytosis; Platelet-Derived Growth Factor; Reverse Transcriptase Polymerase Chain Reaction | 2007 |
Anti-fibrotic effects of a methylenedioxybenzene compound, CW209292 on dimethylnitrosamine-induced hepatic fibrosis in rats.
Topics: Animals; Benzodioxoles; Body Weight; Cell Proliferation; Dimethylnitrosamine; Disease Models, Animal; Female; Hepatic Stellate Cells; Hydroxyproline; Immunohistochemistry; Liver; Liver Cirrhosis; Male; Molecular Structure; Prothrombin Time; Rats; Rats, Sprague-Dawley; Survival Analysis; Thiazoles | 2009 |
Antifibrotic effects of green tea on in vitro and in vivo models of liver fibrosis.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cell Line; Cell Proliferation; Collagen Type I; Dimethylnitrosamine; Disease Models, Animal; Hepatic Stellate Cells; Hydroxyproline; Lipid Peroxides; Liver Cirrhosis; Male; Plant Extracts; Rats; Rats, Inbred Strains; Tea; Treatment Outcome | 2009 |
Evaluation of the influence of proline, hydroxyproline or pyrrolidine in the presence of sodium nitrite on N-nitrosamine formation when heating cured meat.
Topics: Carcinogens; Chromatography, Gas; Dimethylnitrosamine; Hydroxyproline; Limit of Detection; Meat; N-Nitrosopyrrolidine; Nitrosamines; Proline; Pyrrolidines; Sodium Nitrite; Temperature | 2010 |
[Inhibitory effect of anluohuaxianwan on experimental hepatic fibrosis in rats].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Dimethylnitrosamine; Drug Combinations; Drugs, Chinese Herbal; Hyaluronic Acid; Hydroxyproline; Immunohistochemistry; Liver; Liver Cirrhosis, Experimental; Liver Function Tests; Male; Matrix Metalloproteinase 2; Plants, Medicinal; Random Allocation; Rats; Rats, Sprague-Dawley | 2010 |
Experimental evidence for the protective effects of coffee against liver fibrosis in SD rats.
Topics: Animals; Antioxidants; Body Weight; Coffea; Coffee; Cytokines; Dimethylnitrosamine; Disease Models, Animal; Gene Expression; Hepatic Stellate Cells; Hydroxyproline; Liver; Liver Cirrhosis; Macrophages; Male; Malondialdehyde; Necrosis; Nitric Oxide; Nitric Oxide Synthase Type II; Organ Size; Phytotherapy; Plant Extracts; Platelet-Derived Growth Factor; Rats; Rats, Sprague-Dawley; Seeds | 2010 |
[Uniform designed research on the active ingredients assembling of huangqi decoction for inhibition of DMN-induced liver fibrosis].
Topics: Alanine Transaminase; Animals; Dimethylnitrosamine; Drug Interactions; Drugs, Chinese Herbal; Hydroxyproline; Liver Cirrhosis, Experimental; Male; Rats; Rats, Wistar | 2011 |
[Effect of gypenosides on DMN-induced liver fibrosis in rats].
Topics: Animals; Body Weight; Dimethylnitrosamine; Glutathione; Glutathione Peroxidase; Gynostemma; Hydroxyproline; Liver; Liver Cirrhosis; Male; Malondialdehyde; Organ Size; Plant Extracts; Rats; Rats, Wistar | 2012 |
[Effects of Chinese herbal medicine Xiaopi Pill in preventing rats from dimethylnitrosamine-induced liver fibrosis].
Topics: Animals; Dimethylnitrosamine; Drugs, Chinese Herbal; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Male; Rats; Rats, Wistar | 2012 |
Paeoniflorin regulates macrophage activation in dimethylnitrosamine-induced liver fibrosis in rats.
Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Benzoates; Bridged-Ring Compounds; Chemical and Drug Induced Liver Injury; Collagen Type I; Desmin; Dimethylnitrosamine; Disease Models, Animal; Glucosides; Hydroxyproline; Kidney; Liver; Liver Cirrhosis; Lung; Macrophages; Male; Monoterpenes; Paeonia; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Spleen; Tumor Necrosis Factor-alpha | 2012 |
[Formula-syndrome correlation study of three classical anti-jaundice formulas in inhibition of liver fibrosis induced by dimethylnitrosamine in rats].
Topics: Animals; Dimethylnitrosamine; Drugs, Chinese Herbal; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Male; Phytotherapy; Rats; Rats, Wistar | 2012 |
[Effect of cordyceps polysaccharide on lipid peroxidation of rats with dimethylnitrosamine-induced liver fibrosis].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blotting, Western; Collagen; Cordyceps; Dimethylnitrosamine; Drug Administration Schedule; gamma-Glutamyltransferase; Glutathione; Glutathione Peroxidase; Hydroxyproline; Immunohistochemistry; Lipid Peroxidation; Liver; Liver Cirrhosis, Experimental; Male; Malondialdehyde; Phytotherapy; Polysaccharides; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; Superoxide Dismutase | 2013 |
[Effects of Corbrin Shugan capsule on dimethylnitrosamine-induced hepatic fibrosis in rats].
Topics: Albumins; Animals; Capsules; Collagen Type III; Dimethylnitrosamine; Drugs, Chinese Herbal; Hydroxyproline; Laminin; Liver Cirrhosis, Experimental; Male; Rats; Rats, Sprague-Dawley; Tissue Inhibitor of Metalloproteinase-1 | 2013 |
Sophocarpine attenuates liver fibrosis by inhibiting the TLR4 signaling pathway in rats.
Topics: Alkaloids; Animals; Bile Ducts; Cell Proliferation; Cells, Cultured; Collagen; Coloring Agents; Dimethylnitrosamine; Hydroxyproline; Liver; Liver Cirrhosis; Male; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Toll-Like Receptor 4 | 2014 |
Lactoferrin protects against chemical-induced rat liver fibrosis by inhibiting stellate cell activation.
Topics: Animals; Body Weight; Dimethylnitrosamine; Disease Models, Animal; Hydroxyproline; Lactoferrin; Liver; Liver Cirrhosis; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Ultrasonography | 2014 |
Measurement of hydroxyproline in collagen with three different methods.
Topics: Animals; Bleomycin; Chromatography, High Pressure Liquid; Collagen; Colorimetry; Dimethylnitrosamine; Hydroxyproline; Liver; Liver Cirrhosis; Lung; Mass Spectrometry; Rats; Rats, Wistar | 2014 |
Whey-hydrolyzed peptide-enriched immunomodulating diet prevents progression of liver cirrhosis in rats.
Topics: Animals; Antioxidants; Cattle; Dimethylnitrosamine; Disease Progression; Glutathione; Hyaluronic Acid; Hydroxyproline; Liver; Liver Cirrhosis; Male; Milk Proteins; Necrosis; Peptides; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Whey Proteins | 2014 |
[Reverse effect of Yinchenhao decoction in dimethyl nitrosamine-induced hepatic fibrosis in rats].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Collagen Type IV; Dimethylnitrosamine; Drugs, Chinese Herbal; Humans; Hydroxyproline; Liver; Liver Cirrhosis; Male; Rats; Rats, Sprague-Dawley | 2014 |
Combination of sorafenib and gadolinium chloride (GdCl3) attenuates dimethylnitrosamine(DMN)-induced liver fibrosis in rats.
Topics: Angiogenic Proteins; Animals; Anti-Inflammatory Agents; Cytokines; Dimethylnitrosamine; Drug Therapy, Combination; Gadolinium; Hepatic Stellate Cells; Hepatocytes; Hydroxyproline; Kupffer Cells; Liver; Liver Cirrhosis; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Rats; Rats, Wistar; Sorafenib | 2015 |
Fibroblast growth factor 21 attenuates hepatic fibrogenesis through TGF-β/smad2/3 and NF-κB signaling pathways.
Topics: Actins; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Collagen Type I; Dimethylnitrosamine; Down-Regulation; Fibroblast Growth Factors; Hepatic Stellate Cells; Hydroxyproline; Liver; Liver Cirrhosis; Male; Mice; Mice, Inbred ICR; NF-kappa B; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta | 2016 |
Hepatoprotective effects of zingerone on carbon tetrachloride- and dimethylnitrosamine-induced liver injuries in rats.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Antioxidants; Aspartate Aminotransferases; Biomarkers; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytoprotection; Dimethylnitrosamine; Guaiacol; Hep G2 Cells; Hepatic Stellate Cells; Humans; Hydroxyproline; Inflammation Mediators; Lipid Peroxidation; Liver; Liver Cirrhosis, Experimental; Male; Mitogen-Activated Protein Kinases; Oxidative Stress; Rats, Sprague-Dawley; Signal Transduction | 2016 |
Huangqi decoction alleviates dimethylnitrosamine-induced liver fibrosis: An analysis of bile acids metabolic mechanism.
Topics: Animals; Astragalus propinquus; Bile Acids and Salts; Biomarkers; Cell Proliferation; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Dimethylnitrosamine; Drugs, Chinese Herbal; Gene Expression Regulation, Enzymologic; Hepatic Stellate Cells; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Male; Mass Spectrometry; Metabolomics; Protective Agents; Rats, Wistar; RNA, Messenger | 2016 |
Synergistic anti-liver fibrosis actions of total astragalus saponins and glycyrrhizic acid via TGF-β1/Smads signaling pathway modulation.
Topics: Actins; Animals; Astragalus Plant; Cell Line; Cell Survival; Collagen Type I; Common Bile Duct; Dimethylnitrosamine; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Gene Expression Regulation; Glycyrrhizic Acid; Hepatic Stellate Cells; Hydroxyproline; Ligation; Liver; Liver Cirrhosis, Experimental; Male; Mice; Phosphorylation; Phytotherapy; Plants, Medicinal; Protective Agents; Rats, Wistar; RNA, Messenger; Saponins; Signal Transduction; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta1 | 2016 |
Antifibrotic effect of total flavonoids of Astmgali Radix on dimethylnitrosamine-induced liver cirrhosis in rats.
Topics: Actins; Animals; Blotting, Western; Body Weight; Collagen Type I; Dimethylnitrosamine; Drugs, Chinese Herbal; Flavonoids; Hydroxyproline; Liver; Liver Cirrhosis; Male; Organ Size; Plant Extracts; PPAR gamma; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Uncoupling Protein 2 | 2017 |