hydroxyproline has been researched along with ascorbic acid in 192 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 144 (75.00) | 18.7374 |
| 1990's | 23 (11.98) | 18.2507 |
| 2000's | 15 (7.81) | 29.6817 |
| 2010's | 8 (4.17) | 24.3611 |
| 2020's | 2 (1.04) | 2.80 |
| Authors | Studies |
|---|---|
| Omaye, ST; Sauberlich, HE; Turnbull, JD | 1 |
| Mallek, HM; Miller, SA; Nakamoto, T | 1 |
| Takeuchi, T | 1 |
| Chen, TL; Raisz, LG | 1 |
| Berg, RA; Kao, WW; Prockop, DJ | 1 |
| Barnes, MJ | 2 |
| Bates, CJ; Levene, CI | 2 |
| Branson, RE; Cunningham, LW; Hewgley, PB; Lembach, KJ | 1 |
| Cardinale, GJ; Nolan, JC; Undenfriend, S | 1 |
| Fuller, GC; Galligani, L; Lonati-Galligani, M | 1 |
| Fuller, GC; Kaplan, SR; Kuttan, R; Parrott, DP | 1 |
| Colvin, LB; Hunter, B; Lightner, DV; Magarelli, PC | 1 |
| Bowler, EC; Fillios, LC; Krámer, GM | 1 |
| Levenson, GE; Schiltz, JR | 1 |
| Buckingham, RB; Prince, RK; Rodnan, GP; Taylor, F | 1 |
| Dickerson, JW | 1 |
| Bates, CJ | 3 |
| Krane, SM; Quinn, RS | 1 |
| Bates, CJ; Black, AE; Mandal, AR; Patnaik, BK; Paul, AA; Rutishauser, IH | 1 |
| Basu, TK; Donaldson, D; Gillett, MB; Hicklin, JA; Jordan, SJ; Smethurst, M; Williams, DC | 1 |
| Basu, TK; Dickerson, JW | 1 |
| Abedin, MZ; Riemschneider, R | 1 |
| Faris, B; Franzblau, C; Levine, A; Moscaritolo, R; Salcedo, L; Snider, R | 1 |
| Woodruff, CW | 1 |
| Christine, MS; Horner, MR; Olson, M; Pringle, DJ | 1 |
| Grossman, BJ; Quinn, J; Saphykhajon, P | 1 |
| Burke, JM; Ross, R | 1 |
| Arrigoni, O; Arrigoni-Liso, R; Calabrese, G | 1 |
| Coulouris, C; Ikkos, DG; Liakakos, D; Ntalles, K; Vlachos, P | 2 |
| Georgi, GR; Kalbe, I; Reinhardt, C; Schmidt, UJ; Weber, R | 1 |
| Bright-See, E; Rao, AV; Ten Cate, AR; Veen-Baigent, MJ | 1 |
| Lembach, KJ | 1 |
| Mishra, BN; Patnaik, BK | 1 |
| Blanck, TJ; Peterkofsky, B | 1 |
| Eskelson, CD; Pirozhkov, SV; Watson, RR | 1 |
| Belser, P; Bonanno, E; Diven, J; Nicosia, RF | 1 |
| Harada, S; Matsumoto, T; Ogata, E | 1 |
| Binderman, I; Boskey, AL; Doty, SB; Stiner, D | 1 |
| Haskell, BE; Johnston, CS | 1 |
| Fisher, E; Heffernan, S; McLennan, SV; Tada, H; Turtle, JR; Yue, DK | 1 |
| Aprahamian, M; Bruch, JF; Chalkiadakis, G; Grenier, JF; Maldonado, H; Olender, S; Vaxman, F; Volkmar, P; Wittmann, T | 1 |
| Hevia, P; Jacob, RA; Omaye, ST | 1 |
| Davis, HA; Labbe, RF; Rettmer, RL; Skogerboe, KJ | 1 |
| Borel, JP; Monboisse, JC; Monboisse, V; Randoux, A | 1 |
| Berry, L; Shuttleworth, CA | 1 |
| Bellon, G; Borel, JP; Coustry, F; Gillery, P | 1 |
| Haskell, BE; Johnston, CS; Kolb, WP | 1 |
| Egorova, ND; Mamedov, LA; Nikolaev, AV; Novikova, AN; Shekhter, AB | 1 |
| Geesin, J; Murad, S; Pinnell, SR | 1 |
| Azzia, N; Garozzo, S; Micale, C; Romeo, MA; Schilirò, G | 1 |
| Aurer-Kozelj, J; Bühler, E; Buzina, R; Gey, KF; Srdak-Jorgić, K | 1 |
| Cartee, GD; Haskell, BE; Johnston, CS | 1 |
| Hillier, K; Roach, HI; Shearer, JR | 1 |
| Hayashi, Y; Horio, F; Makino, S; Ozaki, K; Yoshida, A | 1 |
| Németh-Csóka, M | 1 |
| Keech, MK; McCann, DS; Shimizu, Y | 1 |
| Lavietes, BB | 1 |
| Golub, LM | 1 |
| Chvapil, M; Rokosova, B | 1 |
| Ramp, WK; Thornton, PA | 1 |
| DeJong, BP; Robertson, WV; Schafer, IA | 1 |
| Chvapil, M | 1 |
| Deluca, HF; Martin, SB | 1 |
| Summer, GK; Switzer, BR | 1 |
| Bates, CJ; Levene, CI; Prynne, CJ | 2 |
| Peterkofsky, B | 2 |
| Barnes, MJ; Kodicek, E | 1 |
| Cutroneo, KR; Guzman, NA; Liebelt, AG | 1 |
| Kuttan, R; Radhakrishnan, AN | 1 |
| Basu, TK; Raven, RW; Williams, DC | 1 |
| Barnes, MJ; Hautvast, JG | 1 |
| Zloch, Z | 1 |
| Basu, TK; Dickerson, JW; Raven, RW; Williams, DC | 1 |
| Poe, WE; Wilson, RP | 1 |
| Jimenez, SA; Ramaley, PB; Rosenbloom, J | 1 |
| Brown, RG | 1 |
| Dell'Orco, RT; Kampschmidt, RF; Nash, JH | 1 |
| Heitkamp, DH; Moore, RD; Summer, GK; Switzer, BR; Waters, MD | 1 |
| Chvapil, M; Hurych, J | 2 |
| Skosey, JL | 1 |
| Priest, RE | 1 |
| Juva, K; Prockop, DJ | 1 |
| Eddy, TP | 1 |
| Bates, CJ; Levene, CI; Shoshan, S | 1 |
| Futrell, MF; Kilgore, LT; Windham, F | 2 |
| Harms, RH; Robbins, RC; Simpson, CF | 1 |
| Chrispeels, MJ; Sadava, D | 1 |
| Amato, JJ; Houck, JC; Moore, RD; Waters, MD | 1 |
| Prockop, DJ | 1 |
| Halme, J | 1 |
| Baker, EM; Kutnink, MA; Richmond, VL; Tolbert, BM | 1 |
| Cormier, A; Krook, L; Rivers, JM | 1 |
| Uitto, J | 1 |
| Williams, CB; Windsor, AC | 1 |
| Halme, J; Kahanpää, K; Karhunen, P; Lindy, S; Uitto, J | 1 |
| Hurych, J | 1 |
| Thornton, PA | 1 |
| Bright, HJ; Kivirikko, KI; Prockop, DJ | 1 |
| Bixby, EM; Efron, ML; Hockaday, TD; Meshorer, E; Smith, LH | 1 |
| Kao, KY; McGavack, TH; Previll, JM; Treadwell, CR | 1 |
| Bobek, P; Ginter, E; Ovecka, M | 1 |
| Fuller, GC; Langner, RO | 1 |
| Halme, J; Kaitila, I; Kivirikko, KI; Saxén, L | 1 |
| Loeven, WA | 1 |
| Reynolds, JJ | 2 |
| Chvapil, M; Cmuchalová, B | 2 |
| Jeffrey, JJ; Martin, GR | 2 |
| Robertson, WV; Schafer, IA; Silverman, L; Sullivan, JC | 1 |
| Birge, SJ; Brandt, J; Peck, WA | 1 |
| Bublitz, C; Priest, RE | 1 |
| Hopkins, AL; Sipes, J; Stenchever, MA | 1 |
| Bartsch, H; Bereziat, JC; Ohshima, H | 1 |
| Cross, CE; Dubick, MA; Last, JA; Rucker, RB | 1 |
| Booth, BA; Uitto, J | 1 |
| Dickman, SR | 1 |
| Grant, ME; Jackson, DS; Sear, CH | 1 |
| Mizoguchi, H; Yasumasu, I | 1 |
| Fleming, KA; McGee, JO | 1 |
| Chojkier, M; Peterkofsky, B; Spanheimer, R | 1 |
| Dickerson, JW; Poulter, JM; White, WF | 1 |
| Berg, RA; Crystal, RG; Rennard, SI; Steinmann, B | 1 |
| Bray, DL; Briggs, GM | 1 |
| Charpentier, C; Dagbovie, K; Johnstone, RA; Larregue, M; Lemonnier, A | 1 |
| Dunn, DM; Franzblau, C | 1 |
| Kleinman, HK; Martin, GR; McGarvey, ML | 1 |
| Gitzelmann, R; Rao, VH; Steinmann, B | 1 |
| Hasegawa, T; Inoue, K; Ishikawa, Y; Kasai, T; Tsujimura, M | 1 |
| Costa, DL; Giri, SN; Hatch, GE; Kodavanti, UP; Starcher, B; Winsett, D | 1 |
| Aprahamian, M; Bruch, JF; Didier, E; Grenier, JF; Lambert, A; Nisand, G; Olender, S; Vaxman, F; Volkmar, P | 1 |
| Hough, R; Leboy, PS; Sullivan, TA; Uschmann, B | 1 |
| Chambers, JE; Snawder, JE | 1 |
| Luck, MR; Zhao, Y | 1 |
| Inoue, K; Kasai, T; Komatsubara, H; Tsujimura, M | 1 |
| Acworth, I; Levine, M; Welch, RW | 1 |
| Eleftheriades, EG; Ferguson, AG; Samarel, AM; Spragia, ML | 1 |
| Florer, JB; Fowlkes, JL; Wenstrup, RJ; Witte, DP | 1 |
| Wolf, G | 1 |
| Morisaki, K; Ozaki, S | 1 |
| Ohkura, K; Terada, H | 1 |
| Furumura, M; Ishikawa, O; Kondo, A; Miyachi, Y; Okada, K | 1 |
| Fournier, V; Gouillou-Coustans, MF; Kaushik, SJ | 1 |
| Gaskell, SJ; Gielbert, J; Hebestreit, HF; Jaakkola, P; Maxwell, PH; Mole, DR; Mukherji, M; Pugh, CW; Ratcliffe, PJ; Schofield, CJ; Tian, YM; von Kriegsheim, A; Wilson, MI | 1 |
| Blank, RD; Boskey, AL; Doty, SB | 1 |
| Hayashi, T; Imamura, Y; Sado, Y; Takahashi, S; Yoshikawa, K | 1 |
| Nony, PA; Nowak, G; Schnellmann, RG | 1 |
| Hwang, DF; Lin, TK | 1 |
| GOULD, BS; WOESSNER, JF | 1 |
| GOULD, BS | 1 |
| HERMAN, C; HIWETT, J; VAN ROBERTSON, WB | 1 |
| MEISTER, A; STONE, N | 1 |
| JORGENSEN, O | 1 |
| CMUCHALOVA, B | 1 |
| BERTELSEN, S | 1 |
| MALT, RA; SCOTT, RB | 1 |
| Heintz, JF; Phillips, PH; Thompson, DJ | 1 |
| BERARD, CW; CROWLEY, LV; GEEVER, EF; LEVENSON, SM; ROSEN, H | 1 |
| BARTOS, F | 1 |
| KIRCHHEINER, B | 1 |
| Jia, J; Lai, J; Wang, Y; Xu, Q; Yin, S; Ying, H; Zhao, X | 1 |
| Hirano, J; Itoh, N; Nakanishi, T; Tanaka, K; Taniguchi, T; Wu, X | 1 |
| Babül, A; Dinçer Kaya, FN; Dinçer, S; Gönül, B; Kaplan, B | 1 |
| Evans, GS; Lin, YS; Powers, HJ; Stuart, EL | 1 |
| Banes, AJ; Koller, BH; Maeda, N; Parsons, KK; Yamauchi, M | 1 |
| Jagetia, GC; Mallikarjun Rao, KV; Rajanikant, GK | 1 |
| Nalini, N; Saravanan, N | 1 |
| Boylu, S; Cevikel, MH; Ceylan, F; Kozaci, D; Meteoglu, I; Tuncyurek, P | 1 |
| Augst, H; Ibold, Y; Kaps, C; Lübke, C; Pelz, S; Ringe, J; Sittinger, M | 1 |
| Barron, AE; Ding, S; Pinkas, DM; Raines, RT | 1 |
| Chang, JJ; Chien, CT; Chien, HF; Lee, YH; Yang, MC | 1 |
| Chang, HM; Chien, CT; Hung, GD; Lee, HS; Lee, KL; Li, PC | 1 |
| Alasmari, A; Czernick, D; Lin, SC; Liu, J; Salih, E; Serge, D | 1 |
| Florance, HV; Johns, A; Smirnoff, N; Sultana, N | 1 |
| Aumailley, L; Dubois, MJ; Garand, C; Lebel, M; Marette, A | 1 |
| Danielski, LG; de Jesus, CR; Felisberto, F; Florentino, D; Giustina, AD; Goldim, MP; Kanis, LA; Pereira, GW; Pereira, VD; Petronilho, F; Walczewski, E | 1 |
| Chang, T; Ho, HL; Hou, MC; Hsin, IF; Huang, HC; Huo, TI; Lee, FY; Lee, SD; Lee, WS | 1 |
| Hasenzahl, M; Mertsch, S; Müsken, M; Reichl, S; Schrader, S | 1 |
| Chugaeva, UY; Mahdavian, L; Morozova, NS; Raouf, M | 1 |
12 review(s) available for hydroxyproline and ascorbic acid
| Article | Year |
|---|---|
[Biosynthesis of collagen].
Topics: Adenocarcinoma, Scirrhous; Adult; Amino Acids; Animals; Ascorbic Acid; Cattle; Child; Collagen; Collagen Diseases; Female; Humans; Hydroxyproline; Lung; Marfan Syndrome; Mice; Procollagen-Proline Dioxygenase; Skin Diseases; Stomach Neoplasms | 1975 |
Function of ascorbic acid in collagen metabolism.
Topics: Animals; Ascorbic Acid; Chick Embryo; Collagen; Glycine; Granuloma; Guinea Pigs; Hydroxyproline; Iron; Ketoglutaric Acids; Procollagen-Proline Dioxygenase; Proline; Rats; Scurvy; Skin | 1975 |
Increased collagen accumulation in dermal fibroblast cultures from patients with progressive systemic sclerosis (scleroderma).
Topics: Adolescent; Adult; Ascorbic Acid; Cells, Cultured; Collagen; Culture Media; Female; Fibroblasts; Humans; Hydroxyproline; Male; Middle Aged; Scleroderma, Systemic; Skin; Time Factors | 1978 |
Ascorbic acid--scurvy.
Topics: Adult; Age Factors; Anemia; Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Bone Diseases, Developmental; Capillaries; Child; Collagen Diseases; Connective Tissue; Creatinine; Dentin; Gingival Hemorrhage; Hemorrhage; Humans; Hydroxyproline; Infant; Scurvy; Skin Diseases; Species Specificity | 1975 |
Biological hydroxylations and ascorbic acid with special regard to collagen metabolism.
Topics: Animals; Ascorbic Acid; Carbon Isotopes; Cells, Cultured; Collagen; Culture Techniques; Dopamine beta-Hydroxylase; Granuloma; Guinea Pigs; Hydroxylation; Hydroxylysine; Hydroxyproline; Keto Acids; Lysine; Mixed Function Oxygenases; Oxidation-Reduction; Procollagen-Proline Dioxygenase; Proline; Protein Precursors; Scurvy; Tritium; Urine | 1972 |
Biochemistry of the hydroxyprolines.
Topics: Animals; Ascorbic Acid; Bacteria; Bone Diseases; Chemical Phenomena; Chemistry; Collagen; Collagen Diseases; Endocrine System Diseases; Glycosides; Humans; Hydroxylation; Hydroxylysine; Hydroxyproline; Isomerism; Peptide Hydrolases; Plants; Polyribosomes; Procollagen-Proline Dioxygenase; Proline; Protein Precursors | 1973 |
Control of collagen biosynthesis.
Topics: Amino Acids; Animals; Anti-Bacterial Agents; Ascorbic Acid; Chelating Agents; Citric Acid Cycle; Collagen; Cyclohexanes; Glycolysis; Hydroxyproline; Metals; Mixed Function Oxygenases; Morpholines; Oxygen Consumption; Proline; Pyridines; Quinones; Water-Electrolyte Balance | 1968 |
Ascorbic acid and the biosynthesis of collagen and elastin.
Topics: Animals; Arteries; Ascorbic Acid; Ascorbic Acid Deficiency; Chick Embryo; Collagen; Elastin; Guinea Pigs; Humans; Hydroxyproline; Proline; Protein Binding; Skin | 1969 |
Some basic aspects of bone metabolism in relation to osteoporosis.
Topics: Age Factors; Aged; Ascorbic Acid; Black People; Bone and Bones; Bone Regeneration; Bone Resorption; Calcium; Calcium Isotopes; Carbon Isotopes; Female; Fluorides; Glucocorticoids; Humans; Hydroxyproline; Insulin; Male; Middle Aged; Osteoporosis; Parathyroid Hormone; Sex Factors; Skin; Thyroid Hormones | 1970 |
Elucidation of the biochemical role of ascorbic acid.
Topics: Animals; Ascorbic Acid; Catalysis; Chemical Phenomena; Chemistry; Chick Embryo; Decarboxylation; Dehydroascorbic Acid; Hydroxylation; Hydroxylysine; Hydroxyproline; Ketoglutaric Acids; Lysine; Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase; Procollagen-Proline Dioxygenase; Proline | 1984 |
The mechanism of uptake of ascorbic acid into osteoblasts and leukocytes.
Topics: Animals; Ascorbic Acid; Cells, Cultured; Glucose Transporter Type 1; Hydroxyproline; Leukocytes; Mice; Monosaccharide Transport Proteins; Osteoblasts | 1996 |
[MECHANISM OF ACTION OF ASCORBIC ACID ON THE METABOLISM OF COLLAGEN PROTEINS].
Topics: Ascorbic Acid; Collagen; Glycosaminoglycans; Hydroxyproline; Proline; Proteins; Wound Healing | 1963 |
2 trial(s) available for hydroxyproline and ascorbic acid
| Article | Year |
|---|---|
Urinary hydroxyproline excretion and vitamin C status in healthy young men.
Topics: Adult; Ascorbic Acid; Ascorbic Acid Deficiency; Diet; Dose-Response Relationship, Drug; Erythrocytes; Humans; Hydroxyproline; Leukocytes; Male; Nutritional Status | 1990 |
Effect of pantothenic acid and ascorbic acid supplementation on human skin wound healing process. A double-blind, prospective and randomized trial.
Topics: Adolescent; Adult; Ascorbic Acid; Biomechanical Phenomena; Copper; Double-Blind Method; Female; Humans; Hydroxyproline; Male; Pantothenic Acid; Prospective Studies; Skin; Wound Healing; Zinc | 1995 |
178 other study(ies) available for hydroxyproline and ascorbic acid
| Article | Year |
|---|---|
Effects of ascorbic acid deficiency and of erythorbic acid on blood components in the Cynomolgus monkey.
Topics: Administration, Oral; Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Blood Cell Count; Blood Cells; Blood Platelets; Cholesterol; Creatinine; Erythrocytes; Haplorhini; Hematocrit; Hemoglobins; Hydroxyproline; Leukocytes; Macaca; Macaca fascicularis; Male; Stereoisomerism | 1979 |
In vitro collagen synthesis of tooth germs from newborn rats with protein-energy malnutrition.
Topics: Animals; Animals, Newborn; Ascorbic Acid; Calcium; Collagen; Female; Hydroxyproline; Incisor; Male; Molar; Odontogenesis; Proline; Protein-Energy Malnutrition; Rats; Tooth Germ | 1979 |
The effects of ascorbic acid deficiency on calcium and collagen metabolism in cultured fetal rat bones.
Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Bone and Bones; Calcification, Physiologic; Calcium; Cartilage; Chromatography; Collagen; Dithiothreitol; Fetus; Glucose; Hydroxylation; Hydroxyproline; Microbial Collagenase; Organ Culture Techniques; Organ Size; Procollagen-Proline Dioxygenase; Protein Biosynthesis; Pyridines; Rats; Tryptophan | 1975 |
Ascorbate increases the synthesis of procollagen hydroxyproline by cultured fibroblasts from chick embryo tendons without activation of prolyl hydroxyla.
Topics: Animals; Ascorbic Acid; Cells, Cultured; Chick Embryo; Collagen; Detergents; Enzyme Activation; Fibroblasts; Hydroxyproline; Kinetics; Procollagen-Proline Dioxygenase; Protein Precursors; Tendons | 1975 |
The effect of hypoxia on collagen synthesis in cultured 3T6 fibroblasts and its relationship to the mode of action of ascorbate.
Topics: Ascorbic Acid; Cells, Cultured; Fibroblasts; Hydroxyproline; Lactates; Oxygen; Procollagen-Proline Dioxygenase; Proline | 1976 |
The synthesis of macromolecular 3-hydroxyproline by attaching and confluent cultures of human fibroblasts.
Topics: Ascorbic Acid; Cells, Cultured; Collagen; Fibroblasts; Humans; Hydroxyproline; Kinetics; Male; Procollagen-Proline Dioxygenase; Proline; Skin | 1977 |
The formation of hydroxyproline in collagen by cells grown in the absence of serum.
Topics: Ascorbic Acid; Cell Line; Collagen; Culture Media; Gluconates; Hydroxyproline; Kinetics; Procollagen-Proline Dioxygenase; Sugar Alcohol Dehydrogenases | 1978 |
The role of ascorbic acid in the hydroxylation of peptide-bound proline.
Topics: Ascorbic Acid; Ferrous Compounds; Hydroxyproline; Procollagen-Proline Dioxygenase; Proline | 1979 |
Effect of (+)-catechin on purified prolyl hydroxylase and on collagen synthesis in skin fibroblasts in culture.
Topics: Animals; Ascorbic Acid; Benzopyrans; Catechin; Collagen; Fibroblasts; Humans; Hydroxyproline; In Vitro Techniques; Iron; Kinetics; Mice; Procollagen-Proline Dioxygenase; Protein Biosynthesis; Rabbits; Skin; Time Factors | 1979 |
Effect of ascorbic acid on prolyl hydroxylase activity, collagen hydroxylation and collagen synthesis in human synovial cells in culture.
Topics: Arthritis, Rheumatoid; Ascorbic Acid; Cells, Cultured; Collagen; Humans; Hydroxylation; Hydroxyproline; Procollagen-Proline Dioxygenase; Proteins; Synovial Fluid | 1979 |
Ascorbic acid-dependent collagen formation in penaeid shrimp.
Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Body Weight; Collagen; Decapoda; Diet; Hydroxyproline; Procollagen-Proline Dioxygenase | 1979 |
Ascorbic acid treatment on early collagen production and wound healing in the guinea pig.
Topics: Animals; Ascorbic Acid; Collagen; Connective Tissue; Guinea Pigs; Hydroxyproline; Male; Skin; Skin Physiological Phenomena; Time Factors; Wound Healing | 1979 |
The role of ascorbic acid on the structural integrity of developing tooth germs.
Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Collagen; Hydroxyproline; Mice; Odontoblasts; Odontogenesis; Proline; Tooth Germ | 1979 |
Nutrition and breast cancer.
Topics: Animals; Ascorbic Acid; Bone Neoplasms; Breast Neoplasms; Calcium; Dietary Fats; Feeding Behavior; Female; Fluorouracil; Humans; Hydroxyproline; Lipase; Lipids; Mammary Neoplasms, Experimental; Mice; Neoplasm Metastasis; Rats; Thiamine Deficiency; Thiamine Pyrophosphate | 1979 |
Vitamin C deficiency in guinea pigs: variable sensitivity of collagen at different sites.
Topics: Adrenal Glands; Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Blood Proteins; Body Weight; Collagen; Complement C1; Guinea Pigs; Hydroxyproline; Liver; Organ Size; Proline; Spleen | 1979 |
Collagen synthesis by cultured skin fibroblasts from siblings with hydroxylysine-deficient collagen.
Topics: Ascorbic Acid; Collagen; Ehlers-Danlos Syndrome; Fibroblasts; Humans; Hydroxylation; Hydroxylysine; Hydroxyproline; Lysine; Proline; Skin | 1979 |
Vitamin C deficiency in guinea pigs: changes in urinary excretion of proline, hydroxyproline and total amino nitrogen.
Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Creatinine; Guinea Pigs; Hydroxyproline; Male; Nitrogen; Proline | 1979 |
Long-term vitamin status and dietary intake of healthy elderly subjects. 2. Vitamin C.
Topics: Aged; Ascorbic Acid; Creatinine; Dehydroascorbic Acid; Diet; Female; Food, Fortified; Humans; Hydroxyproline; Leukocytes; Male; Nutritional Physiological Phenomena; Proline | 1979 |
Ascorbic acid therapy for the relief of bone pain in Paget's disease.
Topics: Aged; Alkaline Phosphatase; Ascorbic Acid; Female; Humans; Hydroxyproline; Male; Osteitis Deformans; Pain | 1978 |
Specific vitamin deficiencies and their significance in patients with cancer and receiving chemotherapy.
Topics: Ascorbic Acid; Ascorbic Acid Deficiency; Breast Neoplasms; Female; Humans; Hydroxyproline; Lipid Metabolism; Neoplasm Metastasis; Neoplasms; Thiamine Deficiency; Vitamin A; Vitamin A Deficiency | 1977 |
[Collagen- and total-vitamin c-content of humanplacentae (author's transl)].
Topics: Ascorbic Acid; Collagen; Female; Gestational Age; Humans; Hydroxyproline; Placenta; Pregnancy | 1978 |
Effect of ascorbate on collagen synthesis by lung embryonic fibroblasts.
Topics: Amino Acids; Ascorbic Acid; Cell Line; Collagen; Fibroblasts; Humans; Hydroxyproline; Lung; Pancreatic Elastase; Solubility | 1978 |
Nutritional status of Chippewa Head Start children in Wisconsin.
Topics: Ascorbic Acid; Body Height; Body Weight; Child; Child Nutritional Physiological Phenomena; Child Welfare; Child, Preschool; Creatinine; Dietary Proteins; Female; Growth; Hematocrit; Hemoglobins; Humans; Hydroxyproline; Indians, North American; Iron; Male; Nutrition Surveys; Wisconsin | 1977 |
Effect of ascorbic acid on urinary hydroxyproline of children receiving corticosteroids.
Topics: Adolescent; Arthritis, Juvenile; Ascorbic Acid; Child; Female; Humans; Hydroxyproline; Male; Prednisone | 1977 |
Proline and hydroxyproline excretion and vitamin C status in elderly human subjects.
Topics: Aged; Ascorbic Acid; Ascorbic Acid Deficiency; Creatinine; Female; Humans; Hydroxyproline; Male; Proline | 1977 |
Collagen synthesis by monkey arterial smooth muscle cells during proliferation and quiescence in culture.
Topics: Ascorbic Acid; Blood; Cell Division; Cells, Cultured; Collagen; Culture Media; Hydroxyproline; Muscle Proteins; Muscle, Smooth; Proline | 1977 |
Ascorbic acid requirement for biosynthesis of hydroxyproline-containing proteins in plants.
Topics: Aerobiosis; Ascorbic Acid; Hydroxyproline; Phenanthridines; Plant Proteins; Plants | 1977 |
Effect of ascorbic acid on urinary hydroxyproline in children receiving corticosteroids.
Topics: Adrenal Cortex Hormones; Animals; Arthritis, Juvenile; Ascorbic Acid; Child; Guinea Pigs; Humans; Hydroxyproline | 1977 |
[Ageing-changes in collagen -- biosynthesis of collagen (part II) (author's transl)].
Topics: Aging; Aorta; Ascorbic Acid; Bone and Bones; Collagen; Connective Tissue; Heart Valves; Hormones; Humans; Hydroxyproline; Lung; Methods; Myocardium; Nutritional Physiological Phenomena; Temperature; Tendons; Wound Healing | 1976 |
Effects of ascorbic acid on health parameters in guinea pigs.
Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Body Weight; Cholesterol; Dose-Response Relationship, Drug; Glycine; Guinea Pigs; Hematocrit; Hemoglobins; Hydroxyproline; Iron; Male; Organ Size; Organ Specificity; Phospholipids; Proline; Tooth; Wound Healing | 1975 |
Induction of human fibroblast proliferation by epidermal growth factor (EGF): enhancement by an EGF-binding arginine esterase and by ascorbate.
Topics: Ascorbic Acid; Blood; Cell Division; Cells, Cultured; DNA Replication; Drug Synergism; Esterases; Fibroblasts; Growth Substances; Hydroxyproline | 1976 |
Age-dependent changes in water soluble components (after 10 min incubation at 65 degrees C) of the garden lizard skin.
Topics: Age Factors; Amino Acids; Animals; Ascorbic Acid; Hot Temperature; Hydroxyproline; Lizards; Male; Proteins; Skin; Time Factors | 1975 |
The stimulation of collagen secretion by ascorbate as a result of increased proline hydroxylation in chick embryo fibroblasts.
Topics: Animals; Ascorbic Acid; Cells, Cultured; Chick Embryo; Collagen; Fibroblasts; Hydroxylation; Hydroxyproline; Kinetics; Proline | 1975 |
Chronic ethanol and cocaine-induced hepatotoxicity: effects of vitamin E supplementation.
Topics: Animals; Ascorbic Acid; Chemical and Drug Induced Liver Injury; Cocaine; Dose-Response Relationship, Drug; Drug Synergism; Glutathione; Hepatitis, Alcoholic; Hydroxyproline; Lipid Peroxidation; Liver; Male; Mice; Mice, Inbred C57BL; Vitamin E | 1992 |
Regulation of angiogenesis in vitro by collagen metabolism.
Topics: Animals; Aorta; Ascorbic Acid; Blood Vessels; Cell Division; Cells, Cultured; Collagen; Extracellular Matrix; Hydroxyproline; Male; Microscopy, Electron; Neovascularization, Pathologic; Rats; Rats, Inbred F344 | 1991 |
Role of ascorbic acid in the regulation of proliferation in osteoblast-like MC3T3-E1 cells.
Topics: Analysis of Variance; Animals; Ascorbic Acid; Azetidinecarboxylic Acid; Cell Division; Cell Line; Collagen; DNA; Fibronectins; Hydroxyproline; Mice; Oligopeptides; Osteoblasts; Proline; Protein Biosynthesis | 1991 |
Requirement of vitamin C for cartilage calcification in a differentiating chick limb-bud mesenchymal cell culture.
Topics: Alkaline Phosphatase; Animals; Ascorbic Acid; Calcification, Physiologic; Calcium; Cartilage; Cell Differentiation; Cells, Cultured; Chick Embryo; Extremities; Hydroxyproline; Mesoderm; Microscopy, Electron; Phosphorus; X-Ray Diffraction | 1991 |
Complement component C1q activity and ascorbic acid nutriture in guinea pigs.
Topics: Analysis of Variance; Animal Nutritional Physiological Phenomena; Animals; Ascorbic Acid; Complement C1q; Guinea Pigs; Hydroxyproline; Immunodiffusion; Male | 1991 |
Interaction of ascorbic acid and glucose on production of collagen and proteoglycan by fibroblasts.
Topics: Amino Acids; Ascorbic Acid; Biological Transport; Cells, Cultured; Collagen; Fibroblasts; Glucose; Heparin; Humans; Hydroxyproline; Infant, Newborn; Kinetics; Male; Proteoglycans; Skin; Trypsin | 1991 |
[Improvement in the healing of colonic anastomoses by vitamin B5 and C supplements. Experimental study in the rabbit].
Topics: Anastomosis, Surgical; Animals; Ascorbic Acid; Colonic Diseases; Fibroblasts; Hydroxyproline; Pantothenic Acid; Placebos; Pressure; Rabbits; Trace Elements; Wound Healing | 1990 |
Laser photobioactivation mechanisms: in vitro studies using ascorbic acid uptake and hydroxyproline formation as biochemical markers of irradiation response.
Topics: Ascorbic Acid; Cells, Cultured; Fibroblasts; Humans; Hydroxyproline; In Vitro Techniques; Lasers; Skin | 1990 |
Nonisotopic evaluation of collagen in fibroblasts cultures.
Topics: 4-Chloro-7-nitrobenzofurazan; Ascorbic Acid; Chromatography, High Pressure Liquid; Collagen; Fibroblasts; Fluorenes; Humans; Hydroxyproline; o-Phthalaldehyde; Proline; Skin | 1989 |
Expression of the chondrogenic phenotype by mineralizing cultures of embryonic chick calvarial bone cells.
Topics: Animals; Ascorbic Acid; Cartilage; Cells, Cultured; Chick Embryo; Collagen; Culture Techniques; Glycerophosphates; Hydroxyproline; Molecular Weight; Osteogenesis; Peptide Mapping; Phenotype; Proline; Protein Biosynthesis; Proteins | 1989 |
Cultures of fibroblasts in fibrin lattices: models for the study of metabolic activities of the cells in physiological conditions.
Topics: Ascorbic Acid; Cell Division; Cells, Cultured; Collagen; Dose-Response Relationship, Drug; Extracellular Matrix; Fibrin; Fibroblasts; Humans; Hydroxyproline; In Vitro Techniques; Proline; Time Factors | 1989 |
The effect of vitamin C nutriture on complement component C1q concentrations in guinea pig plasma.
Topics: Animals; Ascorbic Acid; Complement Activating Enzymes; Complement C1; Complement C1q; Guinea Pigs; Hydroxyproline; Immunodiffusion; Male; Nutritional Status | 1987 |
[Ascorbic acid and hydroxyproline levels in the serum and granulation tissue of rats with aseptic and infected wounds].
Topics: Animals; Ascorbic Acid; Asepsis; Granulation Tissue; Hydroxyproline; Male; Rats; Rats, Inbred Strains; Wound Infection; Wounds and Injuries | 1988 |
Ascorbic acid stimulates collagen production without altering intracellular degradation in cultured human skin fibroblasts.
Topics: Ascorbic Acid; Cells, Cultured; Collagen; Fibroblasts; Humans; Hydroxylysine; Hydroxyproline; Infant, Newborn; Male; Skin | 1986 |
Proline, hydroxyproline, and ascorbic acid in thalassemia major.
Topics: Ascorbic Acid; Child; Child, Preschool; Humans; Hydroxyproline; Proline; Thalassemia | 1986 |
Increase of gingival hydroxyproline and proline by improvement of ascorbic acid status in man.
Topics: Adult; Ascorbic Acid; Female; Gingiva; Humans; Hydroxyproline; Male; Nutritional Requirements; Proline | 1986 |
Effect of ascorbic acid nutriture on protein-bound hydroxyproline in guinea pig plasma.
Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Blood Proteins; Complement Activating Enzymes; Complement C1q; Diet; Guinea Pigs; Hydroxyproline; Liver; Male | 1985 |
Ascorbic acid requirements for collagen synthesis (proline hydroxylation) during long-term culture of embryonic chick femurs.
Topics: Animals; Ascorbic Acid; Bone and Bones; Chick Embryo; Collagen; Femur; Hydroxyproline; Kinetics; Organ Culture Techniques; Proline; Tritium | 1985 |
Requirement for ascorbic acid in a rat mutant unable to synthesize ascorbic acid.
Topics: Adrenal Glands; Animals; Ascorbic Acid; Body Weight; Corticosterone; Cytochrome P-450 Enzyme System; Diet; Hydroxyproline; Liver; Nutritional Requirements; Organ Size; Rats; Rats, Mutant Strains; Spleen | 1985 |
[Studies on collagen fibers. V. On changes due to aging in connective tissue. (Comparative chemical and morphological studies].
Topics: Achilles Tendon; Adolescent; Adult; Aged; Aging; Aorta; Ascorbic Acid; Cartilage; Chemical Phenomena; Chemistry; Child; Child, Preschool; Collagen; Connective Tissue; Glycosaminoglycans; Hexosamines; Hexoses; Humans; Hydroxyproline; In Vitro Techniques; Infant; Infant, Newborn; Middle Aged; Skin; Tendons | 1965 |
Human dermal fibroblasts in monolayer tissue culture. Effect of ascorbic acid analogues.
Topics: Adult; Aged; Ascorbic Acid; Child; Collagen; Culture Techniques; Cysteine; Female; Fibroblasts; Glycosaminoglycans; Humans; Hydroquinones; Hydroxyproline; Male; Middle Aged; Proline; Skin; Uronic Acids | 1965 |
Growth and macromolecular synthesis in the 3T6 mouse fibroblast. I. General description and the role of ascorbic acid.
Topics: Animals; Ascorbic Acid; Carbon Isotopes; Cell Line; Collagen; Culture Techniques; Fibroblasts; Glucosamine; Glycosaminoglycans; Hydroxyproline; Macromolecular Substances; Mice; Proline; Protein Biosynthesis; Time Factors; Tryptophan; Uronic Acids | 1970 |
Kinetics of matrix synthesis in cartilage cell cultures.
Topics: Animals; Ascorbic Acid; Cartilage; Cells, Cultured; Chick Embryo; Chondroitin; Collagen; Culture Media; Culture Techniques; Glycosaminoglycans; Hydroxyproline; Kinetics; Proline; Sulfur Isotopes; Time Factors; Tritium | 1971 |
The effect of ascorbic acid on the turnover of collagen in bone in tissue culture.
Topics: Animals; Ascorbic Acid; Bone and Bones; Collagen; Culture Techniques; Hydroxyproline; Mice; Tritium | 1973 |
Relationship between the dose of ascorbic acid and its structural analogs and proline hydroxylation in various biological systems.
Topics: Animals; Ascorbic Acid; Carbon Radioisotopes; Carrageenan; Chick Embryo; Chromatography, Paper; Collagen; Granulation Tissue; Granuloma; Guinea Pigs; Hydroxyproline; Liver; Lung; Muscles; Proline; Proteins; Scurvy; Skin; Ultrafiltration | 1974 |
Skeletal response to exogenous ascorbic acid by vitamins D3 deficient chicks.
Topics: Animals; Ascorbic Acid; Bone and Bones; Bone Resorption; Calcium; Cholecalciferol; Glucose; Hydroxyproline; In Vitro Techniques; Lactates; Phosphates; Poultry; Vitamin D Deficiency | 1966 |
Failure to induce scurvy by ascorbic acid depletion in a patient with Hurler's syndrome.
Topics: Adrenocorticotropic Hormone; Amino Acids; Ascorbic Acid; Biopsy; Bone Development; Dentition; Diet Therapy; Female; Glycosaminoglycans; Hernia, Umbilical; Humans; Hydroxyproline; Infant; Mucopolysaccharidosis I; Phenylalanine; Scurvy; Skin; Tyrosine; Wound Healing | 1968 |
Conflicting hypotheses on experimental silicotic fibrogenesis: new experimental data.
Topics: Animals; Ascorbic Acid; Carbon Isotopes; Collagen; Dust; Granuloma; Guinea Pigs; Hydroxyproline; Liver; Lung; Muscles; Organ Size; Proline; Silicon Dioxide; Silicosis | 1967 |
A chick serum fraction that stimulates alkaline phosphatase activity in embryonic chick femora in culture.
Topics: Alkaline Phosphatase; Amino Acids; Animals; Ascorbic Acid; Cattle; Charcoal; Chick Embryo; Chromatography, Gel; Culture Techniques; Cysteine; Dialysis; Diphosphates; DNA; Drug Stability; Enzyme Induction; Femur; Hexosamines; Hot Temperature; Humans; Hydrogen-Ion Concentration; Hydroxyproline; L-Lactate Dehydrogenase; Peptide Hydrolases; Phosphoric Monoester Hydrolases; Proline; Serum Albumin; Time Factors | 1969 |
Collagen synthesis in human skin fibroblasts: effects of ascorbate, -ketoglutarate and ferrous ion on proline hydroxylation.
Topics: Ascorbic Acid; Cell Division; Collagen; Culture Media; Culture Techniques; Diploidy; DNA; Fibroblasts; Humans; Hydroxylation; Hydroxyproline; Iron; Ketoglutaric Acids; Male; Osmolar Concentration; Procollagen-Proline Dioxygenase; Proline; Skin; Sodium | 1972 |
The synthesis of underhydroxylated collagen by 3 T6 mouse fibroblasts in culture.
Topics: Animals; Ascorbic Acid; Carbon Isotopes; Cell Line; Chick Embryo; Chromatography, Paper; Collagen; Fibroblasts; Hydroxylation; Hydroxyproline; Kinetics; Mice; Microbial Collagenase; Proline; Proteins; Tritium; Tryptophan | 1972 |
The effect of ascorbic acid on collagen polypeptide synthesis and proline hydroxylation during the growth of cultured fibroblasts.
Topics: Animals; Ascorbic Acid; Carbon Isotopes; Cell Line; Collagen; Drug Stability; Fibroblasts; Hydroxylation; Hydroxyproline; Kinetics; L Cells; Mice; Microbial Collagenase; Proline; Protein Biosynthesis | 1972 |
Ascorbate-dependent differences in the hydroxylation of proline and lysine in collagen synthesized by 3T6 fibroblasts in culture.
Topics: Ascorbic Acid; Carbon Isotopes; Cells, Cultured; Collagen; Culture Media; Fibroblasts; Hydroxylation; Hydroxylysine; Hydroxyproline; Lysine; Microbial Collagenase; Proline; Protein Biosynthesis; Tritium | 1972 |
Elevation of peptidylproline hydroxylase activity and collagen synthesis in spontaneous primary mammary cancers of inbred mice.
Topics: Animals; Ascorbic Acid; Carbon Isotopes; Collagen; Hydroxyproline; Iron; Ketoglutaric Acids; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred A; Mice, Inbred C3H; Mice, Inbred CBA; Mice, Inbred DBA; Mice, Inbred Strains; Mixed Function Oxygenases; Procollagen-Proline Dioxygenase; Proline; Rodent Diseases | 1972 |
Proceedings: Urinary hydroxyproline and leucocyte ascorbic acid levels in patients bearing breast tumour with skeletal metastases.
Topics: Age Determination by Skeleton; Ascorbic Acid; Breast Neoplasms; Collagen; Female; Humans; Hydroxyproline; Leukocytes; Male; Neoplasm Metastasis | 1974 |
Collagen metabolism in folic acid deficiency.
Topics: Animals; Ascorbic Acid; Collagen; Colorimetry; Diet; Elastin; Erythrocyte Count; FIGLU Test; Folic Acid Deficiency; Growth Disorders; Hematocrit; Hemoglobins; Hydroxylation; Hydroxyproline; Leukocyte Count; Male; Proline; Protein Biosynthesis; Rats; Skin; Trichloroacetic Acid; Tritium | 1974 |
[Regulatory influence of peroral dehydroascorbic acid and bioflavonoids on the biochemical function of vitamin C].
Topics: Animals; Ascorbic Acid; Benzopyrans; Catechols; Ceruloplasmin; Cholesterol; Flavonoids; Guinea Pigs; Hydroxyproline; Male; Proline; Rutin; Time Factors | 1974 |
Leucocyte ascorbic acid and urinary hydroxyproline levels in patients bearing breast cancer with skeletal metastases.
Topics: Ascorbic Acid; Bone Neoplasms; Breast Neoplasms; Female; Humans; Hydroxyproline; Leukocytes; Male; Neoplasm Metastasis; Time Factors | 1974 |
Regulation of collagen secretion by ascorbic acid in 3T3 and chick embryo fibroblasts.
Topics: Animals; Ascorbic Acid; Carbon Isotopes; Cell Line; Chick Embryo; Collagen; DNA; Fibroblasts; Hydroxylation; Hydroxyproline; Mice; Mice, Inbred Strains; Proline; Protein Biosynthesis; Time Factors | 1972 |
Impaired collagen formation in the scorbutic channel catfish.
Topics: Alkaline Phosphatase; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Ascorbic Acid; Collagen; Fishes; Fractures, Bone; Hydroxyproline; Pigmentation Disorders; Radiography; Scurvy; Spinal Diseases; Spine | 1973 |
Conformation of underhydroxylated collagen synthesized by 3T6 fibroblasts in culture.
Topics: Anaerobiosis; Animals; Ascorbic Acid; Carbon Isotopes; Cell Line; Collagen; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Hydroxyproline; Mice; Proline; Protein Conformation; Sodium Dodecyl Sulfate | 1973 |
Possible problems of large intakes of ascorbic acid.
Topics: Animals; Ascorbic Acid; Bone and Bones; Calcium; Chickens; Humans; Hydroxyproline; Oxygen Consumption; Phosphates; Stimulation, Chemical; Swine | 1973 |
Effects of ascorbic acid on collagen synthesis in nonmitotic human diploid fibroblasts.
Topics: Ascorbic Acid; Cell Line; Cells, Cultured; Diploidy; Fibroblasts; Humans; Hydroxyproline; Male; Mitosis; Penis; Time Factors | 1973 |
Alkaline phosphatase activation and collagen synthesis in human skin fibroblasts in culture.
Topics: Alkaline Phosphatase; Ascorbic Acid; Carbon Radioisotopes; Cells, Cultured; Collagen; Enzyme Activation; Fibroblasts; Humans; Hydroxyproline; Kinetics; Prednisolone; Proline; Skin | 1973 |
Effect of ascorbic acid on urinary hydroxyproline of children receiving corticosteroids.
Topics: Adolescent; Ascorbic Acid; Bone and Bones; Child; Collagen; Female; Humans; Hydroxyproline; Male; Prednisolone; Rheumatic Fever | 1974 |
Formation of epithelial basement membrane is restricted by scurvy in vitro and is stimulated by vitamin C.
Topics: Ascorbic Acid; Basement Membrane; Culture Media; Culture Techniques; Epithelium; Fluorescent Antibody Technique; Hydroxyproline; Neoplasms, Experimental; Proline; Scurvy; Tritium | 1970 |
Formation of enzyme-substrate complexes with protocollagen proline hydroxylase and large polypeptide substrates.
Topics: Animals; Ascorbic Acid; Carbon Isotopes; Cartilage; Chemical Phenomena; Chemistry; Chick Embryo; Chromatography, Gel; Collagen; Drug Stability; Edetic Acid; Hydroxyproline; Iron; Ketoglutaric Acids; Kinetics; Methods; Mixed Function Oxygenases; Molecular Weight; Peptide Biosynthesis; Peptides; Proline; Puromycin; Tibia | 1969 |
A study of the relationship between Hess tests and leucocyte ascorbic acid in a clinical trial.
Topics: Aged; Ascorbic Acid; Ascorbic Acid Deficiency; Capillary Fragility; Collagen; Humans; Hydroxyproline; Leukocytes; Proline; Pulse | 1972 |
The effect of ascorbic acid on the cross-linking of collagen during its synthesis by cultured 3 T6 fibroblasts.
Topics: Acetates; Animals; Ascorbic Acid; Cell Line; Collagen; Electrophoresis, Disc; Fibroblasts; Hydrogen-Ion Concentration; Hydroxylation; Hydroxyproline; Mice; Proline; Sodium Chloride; Solubility; Tritium | 1972 |
Nutritional status of Negro preschool children in Mississippi. Evaluation of HOP index.
Topics: Ascorbic Acid; Black People; Body Height; Body Weight; Calcium, Dietary; Cephalometry; Child Nutritional Physiological Phenomena; Child, Preschool; Computers; Creatinine; Diet; Dietary Proteins; Ethnicity; Evaluation Studies as Topic; Female; Hemoglobins; Humans; Hydroxyproline; Iron; Male; Mass Screening; Mathematics; Methods; Mississippi; Nutrition Disorders; Nutrition Surveys; Riboflavin; Serum Albumin; Sex Factors; Socioeconomic Factors; Statistics as Topic; Thiamine; Vitamin A | 1971 |
Nutritional status of Negro preschool children in Mississippi. Impact of education and income.
Topics: Ascorbic Acid; Black People; Blood Proteins; Calcium; Calcium, Dietary; Child Nutritional Physiological Phenomena; Child, Preschool; Creatinine; Diet; Dietary Proteins; Educational Status; Ethnicity; Female; Hemoglobins; Humans; Hydroxyproline; Iron; Male; Mississippi; Nutrition Surveys; Riboflavin; Serum Albumin; Socioeconomic Factors; Thiamine; Vitamin A | 1971 |
Microscopic and biochemical observations of aortae of turkeys fed copper-deficient diets with and without ascorbic acid.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Aorta; Aortic Rupture; Arginine; Ascorbic Acid; Collagen; Copper; Deficiency Diseases; Depression, Chemical; Elastin; Hot Temperature; Hydroxyproline; Male; Metabolism; Microscopy, Electron; Proteins; Solubility; Stimulation, Chemical; Turkeys | 1971 |
Hydroxyproline biosynthesis in plant cells. Peptidyl proline hydroxylase from carrot disks.
Topics: Animals; Ascorbic Acid; Calcium Phosphates; Chick Embryo; Collagen; Cytoplasm; Gels; Hydroxyproline; Iron; Keto Acids; Methods; Mixed Function Oxygenases; Oxygen; Peptides; Plant Cells; Plants; Proline; Quaternary Ammonium Compounds; Sulfates; Tritium | 1971 |
Zinc sulfate-failure as an accelerator of collagen biosynthesis and fibroblast proliferation.
Topics: Ascorbic Acid; Carbon Isotopes; Cells, Cultured; Collagen; Culture Media; Culture Techniques; Fibroblasts; Humans; Hydroxyproline; Muscles; Proline; Proteins; Skin; Sodium; Sulfates; Tritium; Zinc | 1971 |
Factors controlling exclusively the synthesis of collage proteins in fibrotic lesion.
Topics: Animals; Ascorbic Acid; Carbon Isotopes; Collagen; Fibroblasts; Granulation Tissue; Guinea Pigs; Hydroxyproline; Iron; Models, Biological; Oxygen; Partial Pressure; Proline; Rats; Sclerosis; Skin; Tritium | 1969 |
The intracellular biosynthesis of collagen. Some possible implications for diseases of bone and other connective tissues.
Topics: Animals; Ascorbic Acid; Bone Diseases; Carbon Isotopes; Cartilage; Chemical Phenomena; Chemistry; Chick Embryo; Collagen; Collagen Diseases; Connective Tissue; Connective Tissue Cells; Galactose; Glycine; Hydroxyproline; In Vitro Techniques; Ketoglutaric Acids; Proline; RNA, Messenger; RNA, Transfer | 1969 |
Development of protocollagen proline hydroxylase activity in the chick embryo.
Topics: Animals; Ascorbic Acid; Bone and Bones; Carbon Isotopes; Chick Embryo; Collagen; Gluconates; Heart; Hydroxyproline; Iron; Kidney; Lung; Mixed Function Oxygenases; Myocardium; Proline; Skin; Stimulation, Chemical; Time Factors | 1969 |
Efficacy of the ascorbic acid stereoisomers in proline hydroxylation in vitro.
Topics: Animals; Ascorbic Acid; Chick Embryo; Hydroxyproline; Methods; Mixed Function Oxygenases; Proline; Stereoisomerism; Tritium; Water | 1969 |
Biochemical and histological study of guinea pig fetal and uterine tissue in ascorbic acid deficiency.
Topics: Adrenal Glands; Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Bone and Bones; Collagen; Connective Tissue; Diet; Female; Fetus; Guinea Pigs; Hydroxyproline; Organ Size; Pregnancy; Proline; Tendons; Tibia; Umbilical Cord; Uterus | 1970 |
A method for studying collagen biosynthesis in human skin biopsies in vitro.
Topics: Adolescent; Adult; Aged; Aging; Ampicillin; Ascorbic Acid; Biopsy; Buffers; Carbon Isotopes; Child; Child, Preschool; Collagen; Glucose; Humans; Hydrogen-Ion Concentration; Hydroxyproline; In Vitro Techniques; Iron; Kinetics; Methods; Middle Aged; Mixed Function Oxygenases; Nitrogen; Oxygen; Phosphates; Proline; Skin; Time Factors | 1970 |
Urinary hydroxyproline in the elderly with low leucocyte ascorbic acid levels.
Topics: Aged; Ascorbic Acid; Ascorbic Acid Deficiency; Collagen; Creatinine; Female; Humans; Hydroxyproline; Leukocytes; Male; Middle Aged | 1970 |
Protocollagen proline hydroxylase activity in experimental pulmonary fibrosis of rats.
Topics: Animals; Ascorbic Acid; Collagen; Disease Models, Animal; Hydroxyproline; Iron; Ketoglutaric Acids; Mixed Function Oxygenases; Proline; Pulmonary Fibrosis; Rats; Silicosis | 1970 |
Hydroxylation of Proline in vitro I. Hydroxyproline formation in the system containing hydrogen peroxide.
Topics: Ascorbic Acid; Catalysis; Chemical Phenomena; Chemistry; Copper; Free Radicals; Hydrogen Peroxide; Hydroxyproline; Iron; Proline | 1967 |
Effects of ascorbic acid on the skeletal response of chicks to vitamin D deficiency.
Topics: Animals; Animals, Newborn; Ascorbic Acid; Bone and Bones; Chickens; Citrates; Hydroxyproline; Male; Tibia; Vitamin D Deficiency | 1968 |
Kinetic patterns of protocollagen hydroxylase and further studies on the polypeptide substrate.
Topics: Animals; Ascorbic Acid; Carbon Isotopes; Chick Embryo; Collagen; Hydroxyproline; In Vitro Techniques; Ketoglutaric Acids; Kinetics; Mixed Function Oxygenases; Oxygen Consumption; Peptides | 1968 |
Hydroxyprolinemia. 3. The origin of free hydroxyproline in hydroxyprolinemia. Collagen turnover. Evidence for biosynthetic pathway in man.
Topics: Amino Acid Metabolism, Inborn Errors; Ascorbic Acid; Carbon Isotopes; Collagen; Diet Therapy; Glutarates; Glyoxylates; Humans; Hydroxyproline; Oxidoreductases | 1968 |
Connective tissue. XVII. Protocollagen hydroxylase of pig uterus.
Topics: Air; Animals; Ascorbic Acid; Carbon Dioxide; Carbon Isotopes; Chick Embryo; Collagen; Connective Tissue; Female; Hydroxyproline; In Vitro Techniques; Ketoglutaric Acids; Lysine; Mixed Function Oxygenases; Nitrogen; Oxygen; Proline; Swine; Temperature; Uterus | 1968 |
Model of chronic hypovitaminosis C in guinea-pigs.
Topics: Adipose Tissue; Adrenal Glands; Animals; Aorta; Ascorbic Acid; Ascorbic Acid Deficiency; Blood Proteins; Body Weight; Brain Chemistry; Duodenum; Erythrocyte Count; Guinea Pigs; Hemoglobins; Hydroxyproline; Kidney; Leukocyte Count; Liver; Male; Models, Biological; Spleen | 1968 |
Elevation of proline hydroxylase activity in diseased rabbit aorta.
Topics: Animals; Aorta; Aortic Diseases; Arteriosclerosis; Ascorbic Acid; Collagen; Epinephrine; Hydroxyproline; Iron; Ketoglutaric Acids; Kinetics; Liver; Male; Mixed Function Oxygenases; Organ Specificity; Proline; Rabbits; Rats; Species Specificity; Stimulation, Chemical; Thyroxine; Tritium; Water | 1969 |
Effect of tetracycline on collagen biosynthesis in cultured embryonic bones.
Topics: Animals; Ascorbic Acid; Bone and Bones; Collagen; Culture Media; Female; Hydroxyproline; Iron; Ketoglutaric Acids; Mice; Mixed Function Oxygenases; Pregnancy; Pregnancy, Animal; Proline; Tetracycline; Ulna | 1969 |
Elastolysis. 3. The release of carbohydrate moieties during the incubation of acid- and alkali-treated elastin with the enzymes of the elastase complex.
Topics: Acetates; Animals; Ascorbic Acid; Borates; Cattle; Chemical Phenomena; Chemistry; Chromatography; Elastin; Hexosamines; Hexoses; Hydroxyproline; In Vitro Techniques; Ligaments; Neuraminic Acids; Pancreatic Elastase; Polysaccharides; Sodium Hydroxide | 1965 |
The effect of ascorbic acid on the growth of chick bone rudiments in chemically defined medium.
Topics: Animals; Ascorbic Acid; Bone and Bones; Bone Development; Chick Embryo; Collagen; DNA; Hexosamines; Hydroxyproline; In Vitro Techniques; Organ Size | 1966 |
[The effect of various doses of ascorbic acid on proline hydroxylation in various biological systems].
Topics: Animals; Ascorbic Acid; Carbon Isotopes; Chick Embryo; Hydroxyproline; In Vitro Techniques | 1966 |
The role of ascorbic acid in the biosynthesis of collagen. I. Ascorbic acid requirement by embryonic chick tibia in tissue culture.
Topics: Animals; Ascorbic Acid; Bone and Bones; Chick Embryo; Collagen; Culture Techniques; DNA; Hydroxyproline; Proline; Protein Biosynthesis; RNA; Tibia | 1966 |
The role of ascorbic acid in the biosynthesis of collagen. II. Site and nature of ascorbic acid participation.
Topics: Animals; Ascorbic Acid; Bone and Bones; Chick Embryo; Collagen; Culture Techniques; Dactinomycin; DNA; Hydroxyproline; RNA; Tibia; Uridine | 1966 |
Ascorbic acid deficiency in cultured human fibroblasts.
Topics: Amino Sugars; Ascorbic Acid; Ascorbic Acid Deficiency; Collagen; Connective Tissue; Connective Tissue Cells; Culture Techniques; Endoplasmic Reticulum; Fibroblasts; Histocytochemistry; Humans; Hydroxyproline; Microscopy, Electron; Mitochondria | 1967 |
The synthesis of collagen by chick bone rudiments in vitro.
Topics: Animals; Ascorbic Acid; Bone and Bones; Chick Embryo; Collagen; Glutathione; Hydroxyproline; In Vitro Techniques | 1967 |
Collagen synthesis by isolated bone cells: stimulation by ascorbic acid in vitro.
Topics: Animals; Ascorbic Acid; Bone Development; Carbon Isotopes; Collagen; DNA; Hydroxyproline; Peptide Biosynthesis; Proline; Rats; Solubility; Stimulation, Chemical | 1967 |
The influence of ascorbic acid and tetrahydropteridine on the synthesis of hydroxyproline by cultured cells.
Topics: Animals; Ascorbic Acid; Carbon Isotopes; Culture Media; Culture Techniques; Dactinomycin; Folic Acid; Hydroxyproline; Mercaptoethanol; Mice; Mitosis; Pteridines; RNA; RNA, Messenger | 1967 |
Dimethyl sulfoxide and related compounds. Some effects on human fibroblasts in vitro.
Topics: Acetone; Ascorbic Acid; Culture Techniques; Dimethyl Sulfoxide; Fibroblasts; Humans; Hydroxyproline; Methanol; Mitosis | 1967 |
Monitoring N-nitrosamino acids excreted in the urine and feces of rats as an index for endogenous nitrosation.
Topics: Amino Acids; Animals; Ascorbic Acid; Feces; Hydroxyproline; Male; Nitrosamines; Nitroso Compounds; Proline; Rats; Rats, Inbred Strains; Sarcosine; Sodium Nitrite; Vitamin E | 1982 |
Interactions of ascorbic acid supplementation and bleomycin instillation on murine lung connective tissue metabolism.
Topics: Animals; Ascorbic Acid; Bleomycin; Body Weight; Collagen; Connective Tissue; Desmosine; Diet; Drug Interactions; Elastin; Hydroxyproline; Lung; Mice; Organ Size; Procollagen-Proline Dioxygenase | 1983 |
Collagen biosynthesis by human skin fibroblasts. III. The effects of ascorbic acid on procollagen production and prolyl hydroxylase activity.
Topics: Adult; Ascorbic Acid; Cells, Cultured; Collagen; Fibroblasts; Humans; Hydroxylation; Hydroxyproline; Procollagen; Procollagen-Proline Dioxygenase; Skin | 1981 |
The search for the specific factor in scurvy.
Topics: Ascorbic Acid; Collagen; History, 18th Century; History, Ancient; Humans; Hydroxyproline; Procollagen-Proline Dioxygenase; Scurvy | 1981 |
The nature of the microfibrillar glycoproteins of elastic fibres. A biosynthetic study.
Topics: Animals; Ascorbic Acid; Cattle; Cells, Cultured; Chromatography, Gel; Cytoskeleton; Elastic Tissue; Electrophoresis, Polyacrylamide Gel; Fibronectins; Glycoproteins; Hydroxylysine; Hydroxyproline; Microbial Collagenase | 1981 |
Archenteron formation induced by ascorbate and alpha-ketoglutarate in sea urchin embryos kept in SO2- 4 -free artificial seawater.
Topics: 2,2'-Dipyridyl; Animals; Ascorbic Acid; Gastrula; Hydroxyproline; Ketoglutaric Acids; Procollagen; Procollagen-Proline Dioxygenase; Proline; Sea Urchins; Seawater; Sulfates | 1982 |
The relationship between collagen and C1q biosynthesis in cultured human fibroblasts.
Topics: 2,2'-Dipyridyl; Ascorbic Acid; Cell Division; Cells, Cultured; Collagen; Complement Activating Enzymes; Complement C1q; Complement Pathway, Classical; Fibroblasts; Humans; Hydroxyproline; Procollagen-Proline Dioxygenase; Proteins | 1982 |
Specifically decreased collagen biosynthesis in scurvy dissociated from an effect on proline hydroxylation and correlated with body weight loss. In vitro studies in guinea pig calvarial bones.
Topics: Animals; Ascorbic Acid; Body Weight; Bone and Bones; Collagen; Female; Guinea Pigs; Hydroxyproline; Liver; Procollagen-Proline Dioxygenase; Protein Biosynthesis; Scurvy | 1983 |
Ascorbic acid supplementation and five year survival rates in women with early breast cancer.
Topics: Adult; Aged; Ascorbic Acid; Breast Diseases; Breast Neoplasms; Creatinine; Female; Humans; Hydroxyproline; Longitudinal Studies; Middle Aged; Neoplasm Recurrence, Local; Prognosis | 1984 |
Ascorbate deficiency results in decreased collagen production: under-hydroxylation of proline leads to increased intracellular degradation.
Topics: Ascorbic Acid; Ascorbic Acid Deficiency; Cells, Cultured; Collagen; Fibroblasts; Humans; Hydroxyproline; Kinetics; Lung; Proline | 1983 |
Decrease in bone density in young male guinea pigs fed high levels of ascorbic acid.
Topics: Aging; Ammonium Chloride; Animals; Ascorbic Acid; Bone and Bones; Dose-Response Relationship, Drug; Eating; Guinea Pigs; Hydroxyproline; Male | 1984 |
Prolidase deficiency with iminodipeptiduria: biochemical investigations and first results of attempted therapy.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Ascorbic Acid; Dipeptidases; Dipeptides; Erythrocytes; Female; Humans; Hydroxyproline; Manganese; Phenytoin; Proline | 1981 |
Effects of ascorbate on insoluble elastin accumulation and cross-link formation in rabbit pulmonary artery smooth muscle cultures.
Topics: Animals; Ascorbic Acid; Cells, Cultured; Chemical Phenomena; Chemistry; Collagen; Elastin; Hydroxylation; Hydroxyproline; Lysine; Muscle, Smooth; Pulmonary Artery; Rabbits | 1982 |
Role of endogenous collagen synthesis in the adhesion of human skin fibroblasts.
Topics: Animals; Ascorbic Acid; Cell Adhesion; Cells, Cultured; Collagen; Cycloheximide; Fibroblasts; Humans; Hydroxyproline; Kinetics; Rats; Skin; Skin Physiological Phenomena | 1982 |
Intracellular degradation of newly synthesized collagen is conformation-dependent.
Topics: Ascorbic Acid; Cells, Cultured; Collagen; Drug Stability; Fibroblasts; Hot Temperature; Humans; Hydroxylation; Hydroxyproline; Proline; Protein Conformation | 1981 |
Antiscorbutic activity of 6-bromo-6-deoxy-L-ascorbic acid in the guinea pig.
Topics: Alkaline Phosphatase; Animals; Ascorbic Acid; Body Weight; Brain Chemistry; Guinea Pigs; Hydroxyproline; Kidney; Liver; Male; Scurvy; Spleen; Tibia | 1995 |
Ozone-induced pulmonary functional, pathological, and biochemical changes in normal and vitamin C-deficient guinea pigs.
Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Body Weight; Collagen; Desmosine; Elastin; Female; Guinea Pigs; Hydroxyproline; Lung Diseases; Lung Volume Measurements; Organ Size; Ozone; Procollagen-Proline Dioxygenase; Respiratory Function Tests; Tissue Fixation | 1995 |
Ascorbate modulation of chondrocyte gene expression is independent of its role in collagen secretion.
Topics: Alkaline Phosphatase; Animals; Ascorbic Acid; Azetidinecarboxylic Acid; Blotting, Northern; Bone Development; Cartilage; Cells, Cultured; Chick Embryo; Collagen; Enzyme Induction; Extracellular Matrix; Gene Expression Regulation; Hydroxyproline; Kinetics; Procollagen; Procollagen-Proline Dioxygenase; Proline; RNA, Messenger; Transcription, Genetic | 1994 |
Osteolathyrogenic effects of malathion in Xenopus embryos.
Topics: Abnormalities, Drug-Induced; Animals; Ascorbic Acid; Bone and Bones; Collagen; Connective Tissue; Embryo, Nonmammalian; Hydroxyproline; Malathion; Microscopy, Electron; Procollagen-Proline Dioxygenase; Protein-Lysine 6-Oxidase; Proteins; Xenopus | 1993 |
Identification and measurement of collagen in the bovine corpus luteum and its relationship with ascorbic acid and tissue development.
Topics: Animals; Ascorbic Acid; Cattle; Collagen; Corpus Luteum; Electrophoresis, Polyacrylamide Gel; Extracellular Matrix; Female; Hydroxyproline; Luteal Phase | 1993 |
Synthesis and antiscorbutic activity of vitamin C analogue: L-threo-hex-2-enaro-1,4-lactone ethyl ester in the guinea pig.
Topics: Alkaline Phosphatase; Animals; Ascorbic Acid; Body Weight; Brain Chemistry; Guinea Pigs; Hydroxyproline; Kidney; Liver; Male; Scurvy | 1993 |
Coulometric electrochemical detection of hydroxyproline using 7-chloro-4-nitrobenzo-2-oxa-1,3-diazole.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Ascorbic Acid; Cattle; Cells, Cultured; Collagen; Electrochemistry; Evaluation Studies as Topic; Fibroblasts; Hydroxyproline; Sensitivity and Specificity | 1993 |
Prolyl hydroxylation regulates intracellular procollagen degradation in cultured rat cardiac fibroblasts.
Topics: 2,2'-Dipyridyl; Animals; Ascorbic Acid; Cells, Cultured; Chloroquine; Collagen; Enzyme Inhibitors; Fibroblasts; Gene Expression; Heart Ventricles; Homeostasis; Hydroxylation; Hydroxyproline; Myocardium; Procollagen; Procollagen-Proline Dioxygenase; Proline; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1995 |
Discordant expression of osteoblast markers in MC3T3-E1 cells that synthesize a high turnover matrix.
Topics: 3T3 Cells; Animals; Ascorbic Acid; Biomarkers; Collagen; Extracellular Matrix; Gelatinases; Gene Expression; Genes, Dominant; Hydroxyproline; Mice; Osteoblasts; Osteocalcin; Procollagen; Recombinant Proteins; RNA, Messenger | 1996 |
Synthesis of novel vitamin C phosphodiesters: stability and antioxidant activity.
Topics: Antioxidants; Arbutin; Ascorbic Acid; Bepridil; Biphenyl Compounds; Esters; Free Radicals; Glycolates; Hydroxyproline; Inositol; Magnetic Resonance Spectroscopy; Molecular Structure; Oxidation-Reduction; Phosphorylation; Picrates; Temperature | 1996 |
Intracellular pH regulation of newborn rat skin basal cells.
Topics: Animals; Animals, Newborn; Ascorbic Acid; Blotting, Western; Cells, Cultured; Fluoresceins; Fluorescent Dyes; Fluorometry; Hydrogen-Ion Concentration; Hydroxyproline; Keratins; Kinetics; Rats; Rats, Wistar; Skin; Sodium | 1996 |
Morphological and biochemical analyses on fibroblasts and self-produced collagens in a novel three-dimensional culture.
Topics: Adolescent; Ascorbic Acid; Cell Culture Techniques; Collagen; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Humans; Hydroxyproline; Male; Skin | 1997 |
Hepatic ascorbic acid saturation is the most stringent response criterion for determining the vitamin C requirement of juvenile European sea bass (Dicentrarchus labrax).
Topics: Analysis of Variance; Animals; Ascorbic Acid; Bass; Biological Availability; Diet; Hydroxyproline; Liver; Nutritional Requirements; Tissue Distribution | 2000 |
Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation.
Topics: Amino Acid Sequence; Ascorbic Acid; Cell Hypoxia; Deferoxamine; DNA-Binding Proteins; Ferrous Compounds; Humans; Hydroxylation; Hydroxyproline; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Ligases; Molecular Sequence Data; Nuclear Proteins; Oxygen; Point Mutation; Procollagen-Proline Dioxygenase; Protein Structure, Tertiary; Proteins; Recombinant Fusion Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Transcription Factors; Tumor Cells, Cultured; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases; Ubiquitins; Von Hippel-Lindau Tumor Suppressor Protein | 2001 |
Vitamin C-sulfate inhibits mineralization in chondrocyte cultures: a caveat.
Topics: Alkaline Phosphatase; Animals; Ascorbic Acid; Calcification, Physiologic; Cells, Cultured; Chick Embryo; Chondrocytes; Hydroxyproline; Proteoglycans | 2001 |
Secretion of non-helical collagenous polypeptides of alpha1(IV) and alpha2(IV) chains upon depletion of ascorbate by cultured human cells.
Topics: Antibodies, Monoclonal; Aorta; Ascorbic Acid; Cells, Cultured; Chromatography, Affinity; Collagen; Endothelium, Vascular; Glomerular Mesangium; Humans; Hydroxylation; Hydroxyproline; Immunoblotting; Muscle, Smooth, Vascular; Oxidation-Reduction; Peptide Fragments; Proline; Protein Structure, Quaternary; Protein Structure, Secondary; Umbilical Cord | 2001 |
Collagen IV promotes repair of renal cell physiological functions after toxicant injury.
Topics: Animals; Ascorbic Acid; Basement Membrane; Cell Division; Cells, Cultured; Collagen; Cysteine; Female; Hydroxyproline; Kidney Tubules, Proximal; Kinetics; Oxygen Consumption; Procollagen-Proline Dioxygenase; Rabbits; Sodium-Potassium-Exchanging ATPase | 2001 |
Effect of temperature on dietary vitamin C requirement and lipid in common carp.
Topics: Animal Nutritional Physiological Phenomena; Animals; Ascorbic Acid; Bone and Bones; Carps; Collagen; Dietary Supplements; Digestive System; Glutathione; Hydroxyproline; Lipid Metabolism; Lipid Peroxidation; Muscles; Nutritional Requirements; Proline; Skin; Temperature; Thiobarbituric Acid Reactive Substances; Weight Gain | 2002 |
Biosynthesis of collagen; the influence of ascorbic acid on the proline, hydroxyproline, glycine, and collagen content of regenerating guinea pig skin.
Topics: Ascorbic Acid; Collagen; Glycine; Hydroxyproline; Proline; Scurvy; Skin Physiological Phenomena | 1957 |
Biosynthesis of collagen. III. The direct action of ascorbic acid on hydroxyproline and collagen formation in subcutaneous polyvinyl sponge implants in guinea pigs.
Topics: Animals; Ascorbic Acid; Collagen; Guinea Pigs; Hydroxyproline; Polyvinyls; Proline; Prostheses and Implants | 1958 |
The relation of ascorbic acid to the conversion of proline to hydroxyproline in the synthesis of collagen in the carrageenan granuloma.
Topics: Ascorbic Acid; Carrageenan; Collagen; Encephalomyelitis; Granuloma; Hydroxyproline; Neoplasms; Proline; Vitamins | 1959 |
Function of ascorbic acid in the conversion of proline to collagen hydroxyproline.
Topics: Ascorbic Acid; Biochemical Phenomena; Carbohydrate Metabolism; Collagen; Hydroxyproline; Proline | 1962 |
Effect of ascorbic acid on formation of granulation tissue in open wounds.
Topics: Ascorbic Acid; Collagen; Granulation Tissue; Hexosamines; Hydroxyproline; Scurvy | 1962 |
[BIOCHEMICAL CHANGES DURING THE COURSE OF THE DEVELOPMENT OF CARRAGEENIN GRANULOMA WITH DEFICIENCY OF, OR INCREASED SATURATION WITH ASCORBIC ACID].
Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Carrageenan; Collagen; DNA; Eukaryota; Granulation Tissue; Granuloma; Guinea Pigs; Hydroxyproline; Polysaccharides; Research; Scurvy | 1963 |
PROBLEMS CONCERNING THE DEFINITION AND GRADING OF THE AORTIC ATHEROSCLEROSIS.
Topics: Aging; Aortic Diseases; Arteriosclerosis; Ascorbic Acid; Atherosclerosis; Calcium; Hexosamines; Histocytochemistry; Hydroxyproline; Lipidoses; Lipids; Pathology; Research | 1964 |
INFLUENCE OF THYROXINE ON THE RIBOSOMAL SYNTHESIS OF COLLAGEN.
Topics: Animals; Ascorbic Acid; Collagen; Guinea Pigs; Hydroxyproline; Hyperthyroidism; Hypothyroidism; Metabolism; Pharmacology; Research; Ribosomes; RNA; RNA, Messenger; Scurvy; Thyroxine; Wound Healing | 1964 |
EFFECT OF MAGNESIUM, FLUORIDE, AND ASCORBIC ACID ON METABOLISM OF CONNECTIVE TISSUE.
Topics: Animals; Ascorbic Acid; Blood; Connective Tissue; Fluorides; Guinea Pigs; Hexosamines; Hydroxyproline; Magnesium; Metabolism; Osteochondrodysplasias; Pharmacology; Phosphates; Research; Uronic Acids | 1964 |
SOME STUDIES OF WOUND HEALING: EXPERIMENTAL METHODS, EFFECT OF ASCORBIC ACID AND EFFECT OF DEUTERIUM OXIDE.
Topics: Animals; Ascorbic Acid; Biochemical Phenomena; Biochemistry; Biomedical Technology; Biophysical Phenomena; Biophysics; Chromatography; Collagen; Deuterium; Deuterium Oxide; Equipment and Supplies; Guinea Pigs; Histology; Hydroxyproline; Medical Laboratory Science; Pathology; Pharmacology; Polyvinyls; Proteins; Rats; Research; Scurvy; Skin; Tendons; Wound Healing | 1964 |
EFFECTS OF ASCORBIC ACID ON ELECTROLYTE COMPOSITION OF THE SKIN OF MICE.
Topics: Anions; Ascorbic Acid; Blood; Chlorides; Electrolytes; Estradiol; Hexosamines; Hydrogen-Ion Concentration; Hydroxyproline; Ions; Mice; Pharmacology; Potassium; Research; Skin; Sodium; Sodium, Dietary | 1964 |
HISTOTOPOCHEMISTRY OF ASCORBIC ACID IN TENDON FIBRES.
Topics: Ascorbic Acid; Collagen; Coloring Agents; Cytoplasm; Hydroxyproline; Proline; Proteins; Rats; Research; Silver; Silver Nitrate; Staining and Labeling; Tendons | 1964 |
VITAMIN C DEFICIENCY AND CONNECTIVE TISSUE: HEXOSAMINE, HEXURONIC ACID AND HYDROXYPROLINE IN COSTAL CARTILAGE AND INTACT SKIN OF THE GUINEA PIG.
Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Cartilage; Collagen; Connective Tissue; Costal Cartilage; Glycosaminoglycans; Guinea Pigs; Hexosamines; Hexuronic Acids; Histocytochemistry; Hydroxyproline; Research; Skin; Uronic Acids | 1965 |
[Study on the effect of micronutrients supplementation on health status of children].
Topics: Ascorbic Acid; Bone Density; Calcifediol; Child; Creatinine; Dietary Supplements; Humans; Hydroxyproline; Learning; Micronutrients; Nutritional Status; Riboflavin; Students | 2003 |
Stimulation of differentiation in sodium-dependent vitamin C transporter 2 overexpressing MC3T3-E1 osteoblasts.
Topics: 3T3 Cells; Alkaline Phosphatase; Animals; Ascorbic Acid; Biological Transport; Calcification, Physiologic; Cell Differentiation; Collagen; Gene Expression Regulation, Developmental; Hydroxyproline; Kinetics; Mice; Organic Anion Transporters, Sodium-Dependent; Osteoblasts; Osteopontin; Promoter Regions, Genetic; Recombinant Proteins; RNA, Messenger; Sialoglycoproteins; Sodium-Coupled Vitamin C Transporters; Symporters | 2004 |
Relationships between tensile strength, ascorbic acid, hydroxyproline, and zinc levels of rabbit full-thickness incision wound healing.
Topics: Animals; Ascorbic Acid; Dietary Supplements; Hydroxyproline; Rabbits; Skin; Tensile Strength; Wound Healing; Zinc | 2004 |
Reduced collagen and ascorbic acid concentrations and increased proteolytic susceptibility with prelabor fetal membrane rupture in women.
Topics: Adult; Amino Acids; Ascorbic Acid; Case-Control Studies; Collagen; Disease Susceptibility; Extraembryonic Membranes; Female; Fetal Membranes, Premature Rupture; Humans; Hydroxyproline; Infant, Newborn; Malondialdehyde; Oxidative Stress; Pregnancy; Proteins; Reference Values | 2005 |
Ascorbic acid-independent synthesis of collagen in mice.
Topics: Animals; Ascorbic Acid; Collagen; Female; Hydroxylation; Hydroxyproline; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Knockout; Neovascularization, Pathologic; Neovascularization, Physiologic; Proline; Skin; Weight Loss | 2006 |
Ascorbic acid increases healing of excision wounds of mice whole body exposed to different doses of gamma-radiation.
Topics: Animals; Antioxidants; Ascorbic Acid; Dose-Response Relationship, Radiation; Female; Gamma Rays; Hydroxyproline; Male; Mice; Radiation Injuries; Skin; Wound Healing | 2007 |
Inhibitory effect of Hemidesmus indicus and its active principle 2-hydroxy 4-methoxy benzoic acid on ethanol-induced liver injury.
Topics: Animals; Ascorbic Acid; Benzoates; Central Nervous System Depressants; Collagen; Disease Models, Animal; Ethanol; Fluorescence; Hemidesmus; Hydroxyproline; Lipid Peroxidation; Liver; Liver Diseases, Alcoholic; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Plant Roots; Rats; Rats, Wistar | 2007 |
Supplementation with high-dose ascorbic acid improves intestinal anastomotic healing.
Topics: Anastomosis, Surgical; Animals; Ascorbic Acid; Dose-Response Relationship, Drug; Hydroxyproline; Intestines; Male; Models, Animal; Pressure; Rats; Rats, Wistar; Vitamins; Wound Healing | 2008 |
Effect of different ascorbate supplementations on in vitro cartilage formation in porcine high-density pellet cultures.
Topics: Animals; Ascorbic Acid; Cartilage, Articular; Cell Dedifferentiation; Cells, Cultured; Chondrocytes; Chondrogenesis; Gene Expression Profiling; Hydroxyproline; Swine; Tissue Engineering | 2009 |
Tunable, post-translational hydroxylation of collagen Domains in Escherichia coli.
Topics: Ascorbic Acid; Chromatography, Liquid; Collagen; Escherichia coli; Gene Expression; Genetic Engineering; Humans; Hydroxylation; Hydroxyproline; Mass Spectrometry; Plasmids; Procollagen-Proline Dioxygenase; Proline; Protein Processing, Post-Translational; Transformation, Bacterial | 2011 |
Antioxidant sol-gel improves cutaneous wound healing in streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Apoptosis; Ascorbic Acid; Diabetes Mellitus, Experimental; Drug Delivery Systems; Female; Hydroxyproline; Immunohistochemistry; Phase Transition; Poloxamer; Rats; Rats, Wistar; Reactive Oxygen Species; Skin; Streptozocin; Time Factors; Wound Healing | 2012 |
Green tea extract supplementation ameliorates CCl4-induced hepatic oxidative stress, fibrosis, and acute-phase protein expression in rat.
Topics: Alanine Transaminase; Animals; Antioxidants; Ascorbic Acid; Aspartate Aminotransferases; beta Carotene; Bile; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury, Chronic; Female; Hydroxyproline; Lipid Metabolism; Liver Cirrhosis; Oxidative Stress; Phytotherapy; Plant Extracts; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Reactive Oxygen Species; Tea; Vitamin E | 2012 |
Novel bioactivity of phosvitin in connective tissue and bone organogenesis revealed by live calvarial bone organ culture models.
Topics: Acid Phosphatase; Animals; Antioxidants; Ascorbic Acid; Bone and Bones; Bone Remodeling; Bone Resorption; Calcium; Cell Differentiation; Egg Yolk; Gene Expression Regulation, Developmental; Hydroxyproline; Isoenzymes; Mice; Organ Culture Techniques; Osteoblasts; Osteoclasts; Peptides; Phosvitin; Tartrate-Resistant Acid Phosphatase | 2013 |
Ascorbate deficiency influences the leaf cell wall glycoproteome in Arabidopsis thaliana.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Ascorbic Acid; Cell Wall; Glycoproteins; Hydroxyproline; Light; Molecular Sequence Data; Mutation; Peptides; Peroxidases; Plant Leaves; Protein Transport; Proteome; Sequence Alignment; Subcellular Fractions | 2015 |
Impact of vitamin C on the cardiometabolic and inflammatory profiles of mice lacking a functional Werner syndrome protein helicase.
Topics: Animals; Ascorbic Acid; Chemokines; Endoplasmic Reticulum; Fatty Acids, Unsaturated; Glutathione; Hydroxyproline; Liver; Lysophosphatidylcholines; Male; Metabolome; Mice; Mice, Inbred C57BL; Mutation; Oxidative Stress; Plasminogen Activator Inhibitor 1; Reactive Oxygen Species; RecQ Helicases; Spleen; Transcriptome; Werner Syndrome; Werner Syndrome Helicase | 2015 |
Preoperative vitamin C supplementation improves colorectal anastomotic healing and biochemical parameters in malnourished rats.
Topics: Anastomosis, Surgical; Animals; Ascorbic Acid; Body Weight; Collagen; Colon; Dietary Supplements; Hydroxyproline; Male; Malnutrition; Nitrates; Nitrites; Oxidative Stress; Peroxidase; Preoperative Care; Rats, Wistar; Rectum; Tissue Adhesions; Tumor Necrosis Factor-alpha; Wound Healing | 2016 |
Ascorbate lacks significant influence in rats with bile duct ligation-induced liver injury.
Topics: Animals; Ascorbic Acid; Bile Ducts; Body Weight; Hydroxyproline; Ligation; Liver Cirrhosis, Experimental; Lung Injury; Male; Mesentery; Oxidative Stress; Portasystemic Shunt, Surgical; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A | 2017 |
Cell sheet technology: Influence of culture conditions on in vitro-cultivated corneal stromal tissue for regenerative therapies of the ocular surface.
Topics: Ascorbic Acid; Biocompatible Materials; Cell Culture Techniques; Cell Proliferation; Corneal Stroma; Culture Media; Extracellular Matrix; Fibroblasts; Glutamine; Glycine; Humans; Hydroxyproline; Proline; Regeneration; Serum Albumin, Bovine; Surface Properties; Tensile Strength; Tissue Engineering; Tissue Scaffolds; Transforming Growth Factor beta1 | 2021 |
Effects of L-ascorbic acid (C
Topics: Amino Acids; Ascorbic Acid; Collagen; Glycine; Humans; Hydroxyproline; Mixed Function Oxygenases; Proline; Protein Structure, Secondary | 2023 |